LOCUS       XP_026128284             364 aa            linear   VRT 18-JUN-2025
DEFINITION  epithelial-stromal interaction protein 1-like [Carassius auratus].
ACCESSION   XP_026128284
VERSION     XP_026128284.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272499.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..364
                     /product="epithelial-stromal interaction protein 1-like"
                     /calculated_mol_wt=42812
     Region          <70..>261
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     CDS             1..364
                     /gene="LOC113109024"
                     /coded_by="XM_026272499.1:130..1224"
                     /db_xref="GeneID:113109024"
ORIGIN      
        1 mnrsthlqrn prgsrayrgn einqnsnmtn neqrnenyce nnspnvsnvt snpqnqptha
       61 dgytkippne srrselqrta qegeeklrrl keekrpgpiq lapeklsgae slaevrqrqq
      121 edlrrsklrk klqkeemdqn krqaeeqkne rmkalqreka rklemskkqg deqrqklyqd
      181 dkqmkteefl qrierssssv smaasksmpa sswtknheyr earreeenad llkkkeeqrr
      241 kaevleekqk qqeedrkrrt eadhqrvnma fldhleasss gmvpestnvw lddddddelq
      301 dtalstvpnp sqvhtdceee ddcghmwtlm klqnrfpyye rvmledivkq cngnyqqaye
      361 lldv
//
LOCUS       XP_026128285             149 aa            linear   VRT 18-JUN-2025
DEFINITION  dnaJ homolog subfamily C member 15 isoform X1 [Carassius auratus].
ACCESSION   XP_026128285
VERSION     XP_026128285.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272500.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..149
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..149
                     /product="dnaJ homolog subfamily C member 15 isoform X1"
                     /calculated_mol_wt=15974
     Region          <86..143
                     /region_name="DnaJ"
                     /note="DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock
                     protein 40) proteins are highly conserved and play crucial
                     roles in protein translation, folding, unfolding,
                     translocation, and degradation. They act primarily by
                     stimulating the ATPase activity of Hsp70s; cl02542"
                     /db_xref="CDD:413365"
     Site            order(123..125,130,133..134,137..138)
                     /site_type="other"
                     /note="HSP70 interaction site [polypeptide binding]"
                     /db_xref="CDD:99751"
     CDS             1..149
                     /gene="LOC113109025"
                     /coded_by="XM_026272500.1:145..594"
                     /db_xref="GeneID:113109025"
ORIGIN      
        1 masssgvvme gdfmrnaeyt prstgqsetd idkrlggclm avglgvaaag fagryafhlw
       61 rplsqvitea akkvpstsfs ayykggfeqk mtrreaslvl gisptsskak vreahrrimv
      121 lnhpdkggsp ylaakineak dlldsgprh
//
LOCUS       XP_026128286             127 aa            linear   VRT 18-JUN-2025
DEFINITION  dnaJ homolog subfamily C member 15 isoform X2 [Carassius auratus].
ACCESSION   XP_026128286
VERSION     XP_026128286.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272501.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..127
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..127
                     /product="dnaJ homolog subfamily C member 15 isoform X2"
                     /calculated_mol_wt=13640
     Region          <86..127
                     /region_name="DnaJ"
                     /note="DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock
                     protein 40) proteins are highly conserved and play crucial
                     roles in protein translation, folding, unfolding,
                     translocation, and degradation. They act primarily by
                     stimulating the ATPase activity of Hsp70s; cl02542"
                     /db_xref="CDD:413365"
     CDS             1..127
                     /gene="LOC113109025"
                     /coded_by="XM_026272501.1:145..528"
                     /db_xref="GeneID:113109025"
ORIGIN      
        1 masssgvvme gdfmrnaeyt prstgqsetd idkrlggclm avglgvaaag fagryafhlw
       61 rplsqvitea akkvpstsfs ayykggfeqk mtrreaslvl gisptsskak vreahrrimv
      121 lnhpdkg
//
LOCUS       XP_026128287             259 aa            linear   VRT 18-JUN-2025
DEFINITION  tumor necrosis factor ligand superfamily member 11-like [Carassius
            auratus].
ACCESSION   XP_026128287
VERSION     XP_026128287.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272502.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..259
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..259
                     /product="tumor necrosis factor ligand superfamily member
                     11-like"
                     /calculated_mol_wt=29052
     Region          105..255
                     /region_name="TNF"
                     /note="Tumor Necrosis Factor; TNF superfamily members
                     include the cytokines: TNF (TNF-alpha), LT
                     (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL),
                     Fas ligand, and osteoprotegerin (OPG) ligand. These
                     proteins generally have an intracellular N-terminal...;
                     cd00184"
                     /db_xref="CDD:238108"
     Site            order(108,156,158,220,225,251,255)
                     /site_type="other"
                     /note="trimer interface [polypeptide binding]"
                     /db_xref="CDD:238108"
     Site            order(131..132,137,182,191,196)
                     /site_type="active"
                     /note="receptor binding sites [active]"
                     /db_xref="CDD:238108"
     CDS             1..259
                     /gene="LOC113109026"
                     /coded_by="XM_026272502.1:283..1062"
                     /db_xref="GeneID:113109026"
ORIGIN      
        1 maandyrayl rnhidmeeap graahtgsth ralifgtlav mgllqvassv aillhltgyl
       61 revdlasaqq spneemhset liadtlksik erkdkcrlkk dtrmpaahlp iktptnfsak
      121 nrnsittitw ddnqgmnfkm ryhdgriqve eagyyyvyak tcfryaedhd sskedvsnvq
      181 lfqyifqekf tqsagpaill tksggtvqwn iakynmycve qgrgiqlnng dgiyvnvsna
      241 wlldptadgt yfgtfkisn
//
LOCUS       XP_026128288            1800 aa            linear   VRT 18-JUN-2025
DEFINITION  A-kinase anchor protein 11-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128288
VERSION     XP_026128288.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272503.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1800
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1800
                     /product="A-kinase anchor protein 11-like isoform X1"
                     /calculated_mol_wt=196830
     Region          <1714..1797
                     /region_name="AKAP_110"
                     /note="A-kinase anchor protein 110 kDa (AKAP 110);
                     cl14906"
                     /db_xref="CDD:449376"
     CDS             1..1800
                     /gene="LOC113109027"
                     /coded_by="XM_026272503.1:250..5652"
                     /db_xref="GeneID:113109027"
ORIGIN      
        1 meacsrirgv plksratmkk etiregsnpg lksllkhkke lcnvvvelhn kepqslsevh
       61 yiclpshteg edftlqalts lstemmellr slhvyalkde eilllkdpkr pferkdsvsq
      121 vcsralcilr hsptpqisvc silgllarya agiryalelq vlqrgaseac qaedddtnqs
      181 vssieedfvt afehleeent gghsqrsqrd vasqtvpshl relsgsriii ssiprksvrk
      241 ekaaakvset vlksttwpas sgssyalssl pkghtastyl tesdesdcss pspiifldev
      301 gyqkslkakl dipkipilkd gvedsdsevs effdsfdqfd eldqsfdsni kvlkeqplpg
      361 rtkklvdnsg ckfisrgcst tamnphkfdh rtlpanvkkp tplkpgslyg ihsdspdsqw
      421 pvrtpceesg plfspvcssa fsplgeggsl eyfwktdgdg selhkpqdlc slyktysdfa
      481 nnlskeilgs vcgysspvdf ninknlscvc hkefkntngh lmklsdiqet vtitksqsqs
      541 lkdgiqkfat dlvemslgsa lrdlqkgvss ctttlchlaa rltssvfqma fheigmrhay
      601 vlkeraingl asflvgeais galkeflfvk kqifnntvtr faadlaeelv fegimevcqf
      661 shpstpltps dwsfeqeeev vssyasdlse svlqeafiel sqadvtfttq aaisvsvdni
      721 cyvsaedssl itktcsahss yigsqavaea anqeqdgctv kkalycvsgm ascvpvpmag
      781 kvishvhhpc etsqykssig hvcqtspkrt iccqvevgss tsdsseatqt esspgpariq
      841 dasgeealgn psvekdstkp sigktfqnfs gsmvdtivge afdlmhsstk vkkkvedcad
      901 flsktisari stpshgivks ndastpsqvp fhlvskgscd pssgsicpvs kltpevrsvv
      961 kmdtlevptf evascggrkv sagdfsssns gkksteipst ppsspqqpsd eynekqvrqf
     1021 skklkgtlak effpatpppt pyyppaadtk eeglvsdkad fivklirsls eeagsnedee
     1081 edqedgphsg ncqaelspni rnrmierral hyaerlachi vsmatemdtl sfgdvkklvd
     1141 deskgsvalh saqfseqtln slwtyageva gevisdvkkm mssnhchhkm lkrgsvnsad
     1201 khqsgesllg sltcqwpgdv qvsgsssgms seypscesvt deyagylikv lkkeggnrel
     1261 ildqyatrla yrsiksglah aarkikqrsp lrlhssrrlh sdrspdvsqf ttsksshasl
     1321 idgkdgssce slpcacqdgq dmssneyvel vnfaeslayn itcdvtrklr mssvrlpksl
     1381 tdsclyrkst vedmpenlik ntfscsllpy tesnrlyhst sslndgksdn gviqviehya
     1441 rkivndtlem tlgptcvqaa gdrraldrns fteklaeaye acrycqgrdc mfcsrdgrhg
     1501 fqgvkirrqq esdavtglei prihidlekr aafaeemvss aiekakkels ctslnadsgi
     1561 ghdgasfaes ltteimtsal snvcqtvnlg tsrregvnvt estvsqqlsl svgddslgsw
     1621 snlsfeedhp desssfhhls dssngnsssw sslglegevy eehlsfspsd sdgteekeae
     1681 akedsggavr verehgpter allvvstdiq graedpqlta vlqwiaasia dlslmqlsqf
     1741 saqelqqlpa vaqrlreref rvgdllqall ryfeerrsee evgdtrnshk slfqwlleqa
//
LOCUS       XP_026128289            1799 aa            linear   VRT 18-JUN-2025
DEFINITION  A-kinase anchor protein 11-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128289
VERSION     XP_026128289.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272504.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1799
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1799
                     /product="A-kinase anchor protein 11-like isoform X2"
                     /calculated_mol_wt=196743
     Region          <1713..1796
                     /region_name="AKAP_110"
                     /note="A-kinase anchor protein 110 kDa (AKAP 110);
                     cl14906"
                     /db_xref="CDD:449376"
     CDS             1..1799
                     /gene="LOC113109027"
                     /coded_by="XM_026272504.1:250..5649"
                     /db_xref="GeneID:113109027"
ORIGIN      
        1 meacsrirgv plksratmkk etiregsnpg lksllkhkke lcnvvvelhn kepqslsevh
       61 yiclpshteg edftlqalts lstemmellr slhvyalkde eilllkdpkr pferkdsvsq
      121 vcsralcilr hsptpqisvc silgllarya agiryalelq vlqrgaseac qaedddtnqs
      181 vssieedfvt afehleeent gghsqrsqrd vasqtvpshl relsgsriii ssiprksvrk
      241 ekaaakvset vlksttwpas sgssyalssl pkghtastyl tesdesdcss pspiifldev
      301 gyqkslkakl dipkipilkd gvedsdsevs effdsfdqfd eldqsfdsni kvlkeqplpg
      361 rtkklvdnsg ckfisrgcst tamnphkfdh rtlpanvkkp tplkpgslyg ihsdspdsqw
      421 pvrtpceesg plfspvcssa fsplgeggsl eyfwktdgdg selhkpqdlc slyktysdfa
      481 nnlskeilgs vcgysspvdf ninknlscvc hkefkntngh lmklsdiqet vtitksqsqs
      541 lkdgiqkfat dlvemslgsa lrdlqkgvss ctttlchlaa rltssvfqma fheigmrhay
      601 vlkeraingl asflvgeais galkeflfvk kqifnntvtr faadlaeelv fegimevcqf
      661 shpstpltps dwsfeqeeev vssyasdlse svlqeafiel sqadvtfttq aaisvsvdni
      721 cyvsaedssl itktcsahss yigsqavaea anqeqdgctv kkalycvsgm ascvpvpmag
      781 kvishvhhpc etsqykssig hvcqtspkrt iccqvevgss tsdsseatqt esspgpariq
      841 dasgeealgn psvekdstkp sigktfqnfs gsmvdtivge afdlmhsstk vkkkvedcad
      901 flsktisari stpshgivks ndastpsqvp fhlvskgscd pssgsicpvs kltpevrsvv
      961 kmdtlevptf evascggrkv sagdfsssns gkksteipst ppsspqqpsd eynekqvrqf
     1021 skklkgtlak effpatpppt pyyppaadtk eeglvsdkad fivklirsls eeagsnedee
     1081 edqedgphsg ncqaelspni rnrmierral hyaerlachi vsmatemdtl sfgdvkklvd
     1141 deskgsvalh saqfseqtln slwtyageva gevisdvkkm mssnhchhkm lkrgsvnsad
     1201 khqsgesllg sltcqwpgdv qvsgsssgms seypscesvt deyagylikv lkkeggnrel
     1261 ildqyatrla yrsiksglah aarkikqrsp lrlhssrrlh sdrspdvsqf ttsksshasl
     1321 idgkdgssce slpcacqdgq dmssneyvel vnfaeslayn itcdvtrklr mssvrlpksl
     1381 tdsclyrkst vedmpenlik ntfscsllpy tesnrlyhst sslndgksdn gviqviehya
     1441 rkivndtlem tlgptcvqaa gdrraldrns fteklaeaye acrycqgrdc mfcsrdgrhg
     1501 fqgvkirrqq esdavtglei prihidlekr aafaeemvss aiekakkels ctslnadsgi
     1561 ghdgasfaes ltteimtsal snvcqtvnlg tsrregvnvt estvsqqlsl svgddslgsw
     1621 snlsfeedhp desssfhhls dsngnsssws slglegevye ehlsfspsds dgteekeaea
     1681 kedsggavrv erehgptera llvvstdiqg raedpqltav lqwiaasiad lslmqlsqfs
     1741 aqelqqlpav aqrlrerefr vgdllqallr yfeerrseee vgdtrnshks lfqwlleqa
//
LOCUS       XP_026128290            1771 aa            linear   VRT 18-JUN-2025
DEFINITION  A-kinase anchor protein 11-like isoform X3 [Carassius auratus].
ACCESSION   XP_026128290
VERSION     XP_026128290.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272505.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1771
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1771
                     /product="A-kinase anchor protein 11-like isoform X3"
                     /calculated_mol_wt=193759
     Region          <1685..1768
                     /region_name="AKAP_110"
                     /note="A-kinase anchor protein 110 kDa (AKAP 110);
                     cl14906"
                     /db_xref="CDD:449376"
     CDS             1..1771
                     /gene="LOC113109027"
                     /coded_by="XM_026272505.1:250..5565"
                     /db_xref="GeneID:113109027"
ORIGIN      
        1 meacsrirgv plksratmkk etiregsnpg lksllkhkke lcnvvvelhn kepqslsevh
       61 yiclpshteg edftlqalts lstemmellr slhvyalkde eilllkdpkr pferkdsvsq
      121 vcsralcilr hsptpqisvc silgllarya agiryalelq vlqrgaseac qaedddtnqs
      181 vssieedfvt afehleeent gghsqrsqrd vasqtvpshl relsgsriii ssiprksvrk
      241 ekaaakvset vlksttwpas sgssyalssl pkghtastyl tesdesdcss pspiifldev
      301 gyqkslkakl dipkipilkd gvedsdsevs effdsfdqfd eldqsfdsni kvlkeqplpg
      361 rtkklvdnsg ckfisrgcst tamnphkfdh rtlpanvkkp tplkpgslyg ihsdspdsqw
      421 pvrtpceesg plfspvcssa fsplgeggsl eyfwktdgdg selhkpqdlc slyktysdfa
      481 nnlskeilgs vcgysspvdf ninknlscvc hkefkntngh lmklsdiqet vtitksqsqs
      541 lkdgiqkfat dlvemslgsa lrdlqkgvss ctttlchlaa rltssvfqma fheigmrhay
      601 vlkeraingl asflvgeais galkeflfvk kqifnntvtr faadlaeelv fegimevcqf
      661 shpstpltps dwsfeqeeev vssyasdlse svlqeafiel sqadvtfttq aaisvsvdni
      721 cyvsaedssl itktcsahss yigsqavaea anqeqdgctv kkalycvsgm ascvpvpmag
      781 kvishvhhpc etsqykssig hvcqtspkrt iccqvevgss tsdsseatqt esspgpariq
      841 dasgeealgn psvekdstkp sigktfqnfs gsmvdtivge afdlmhsstk vkkkvedcad
      901 flsktisari stpshgivks ndastpsqvp fhlvskgscd pssgsicpvs kltpevrsvv
      961 kmdtlevptf evascggrkv sagdfsssns gkksteipst ppsspqqpsd eynekqvrqf
     1021 skklkgtlak effpatpppt pyyppaadtk eeglvsdkad fivklirsls eeagsnedee
     1081 edqedgphsg ncqaelspni rnrmierral hyaerlachi vsmatemdtl sfgdvkklvd
     1141 deskgsvalh saqfseqtln slwtyageva gevisdvkkm mssnhchhkm lkrgsvnsad
     1201 khqsgesllg sltcqwpgdv qvsgsssgms seypscesvt deyagylikv lkkeggnrel
     1261 ildqyatrla yrsiksglah aarkikqrsp lrlhssrrlh sdrspdvsqf ttsksshasl
     1321 idgkdgssce slpcacqdgq dmssneyvel vnfaeslayn itcdvtrklr mssvrlpksl
     1381 tdsclyrkst vedmpenlik ntfscsllpy tesnrlyhst sslndgksdn gviqviehya
     1441 rkivndtlem tlgptcvqaa gdrraldrns fteklaeaye acrycqgrdc mfcsrdgrhg
     1501 fqgvkirrqq esdavtglei prihidlekr aafaeemvss aiekakkels ctslnadsgi
     1561 ghdgasfaes ltteimtsal snvcqtvnlg tsrregvnvt estvsqqlsl svgddslgsw
     1621 snlsfeedhp desssfhhls dsdgteekea eakedsggav rverehgpte rallvvstdi
     1681 qgraedpqlt avlqwiaasi adlslmqlsq fsaqelqqlp avaqrlrere frvgdllqal
     1741 lryfeerrse eevgdtrnsh kslfqwlleq a
//
LOCUS       XP_026128291            1305 aa            linear   VRT 18-JUN-2025
DEFINITION  diacylglycerol kinase eta isoform X1 [Carassius auratus].
ACCESSION   XP_026128291
VERSION     XP_026128291.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272506.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1305
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1305
                     /product="diacylglycerol kinase eta isoform X1"
                     /calculated_mol_wt=145522
     Region          95..240
                     /region_name="PH_DGK_type2"
                     /note="Type 2 Diacylglycerol kinase Pleckstrin homology
                     (PH) domain; cd13274"
                     /db_xref="CDD:270093"
     Region          224..309
                     /region_name="C1_DGKeta_rpt1"
                     /note="first protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20848"
                     /db_xref="CDD:410398"
     Region          320..381
                     /region_name="C1_DGKeta_rpt2"
                     /note="second protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20894"
                     /db_xref="CDD:410444"
     Region          412..534
                     /region_name="DAGKc"
                     /note="Diacylglycerol kinase catalytic domain (presumed);
                     smart00046"
                     /db_xref="CDD:214487"
     Region          <680..764
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          858..1015
                     /region_name="DAGKa"
                     /note="Diacylglycerol kinase accessory domain (presumed);
                     smart00045"
                     /db_xref="CDD:214486"
     Region          1234..1297
                     /region_name="SAM_DGK-delta-eta"
                     /note="SAM domain of diacylglycerol kinase delta and eta
                     subunits; cd09507"
                     /db_xref="CDD:188906"
     Site            order(1260..1264,1270..1272,1274..1275,1278)
                     /site_type="other"
                     /note="homooligomer interface ML [polypeptide binding]"
                     /db_xref="CDD:188906"
     Site            order(1273,1277,1282..1286,1288..1289,1292)
                     /site_type="other"
                     /note="homooligomer interface EH [polypeptide binding]"
                     /db_xref="CDD:188906"
     CDS             1..1305
                     /gene="LOC113109029"
                     /coded_by="XM_026272506.1:354..4271"
                     /db_xref="GeneID:113109029"
ORIGIN      
        1 mtakrtafqp lsssripaer kgaagrlhnp epcasspqep ekpaasasgl pasgavgvsg
       61 pvldessdse geqegpqkli rkvstsgqir sktsvkegll lkqtssfqrw kkryfklrgr
      121 tlyyakdaka ggvltrwqyr vsrsrvcwrv lsvcwsgarr qppalgasgs eeglvairsl
      181 ifdevdlsda svaesstknv nnsftvitpf rrlilcaenr kemedwissl ksvqsrehye
      241 taqfnvehfs gmhnwyacsh arptfcnvcr dslsgvtshg lscevckfka hkrcavratn
      301 nckwttlasi gkdiiededg iamphqwleg nlpvsakcav cdktcgsvlr lqdwrclwck
      361 amvhtacmdl yprkcplgqc kvsiipptal nsidsdgfwk atcppscasp llvfvnsksg
      421 dnqgvkflrr fkqllnpaqv fdlvnggphl glrlfqkfdn frilvcggdg svgwvlseid
      481 klnlhkqcql gvlplgtgnd larvlgwgps cdddtqlpqi leklerastk mldrwsimty
      541 eikippkhsc patpedtedg qlqisvyeds vaahltkiln sdqhsvviss skvlcetvke
      601 fvakvgkcye rssdsteead alalkcailn ekldsllqtl nleaqaltps alttppivee
      661 eveeeeleee edlseesite lkenetekgs ahklfrpreq lvlranslkk alrkiieqae
      721 rvvdeqnaht deqelqsptd frkdseeenr dnekdedtke lealplaksp cspperrvsr
      781 stqscgsfsi tpfttskenl pvlntriicp glraglaasi agssiiskml lanidpfgat
      841 pfidpdldfl egylekcvmn nyfgigldak islefnnkre ehpekcrsrt knmmwygvlg
      901 tkellqrtyk nleqkvqlec dgqyiplpsl qgiavlnips yaggtnfwgg tkeddifcap
      961 sfddkilevv avfgsmqmav srviklqhhr iaqcrtvkit ilgdegvpvq vdgeawiqpp
     1021 gvikiqhknr aqmltrdraf entlkswedk lkydkpplrp hlypqhsvdl ateeeatliq
     1081 mcaraaedli triceaaeny qlleqelaha vnasshaink thpkfpeslt rntaievast
     1141 vkalhnetel llvgrvplql dppheellss alqsvelelg klaeipwlyh ilqpndeedn
     1201 sleygkrnsr ggmfrivpkf kkekaqkkss pqsvqrwgte evavwleqls lgeyketfir
     1261 hdirgsellh lerrdlkdlg iskvghmkri lqgtkdlaks smvdl
//
LOCUS       XP_026128292            1283 aa            linear   VRT 18-JUN-2025
DEFINITION  diacylglycerol kinase eta isoform X2 [Carassius auratus].
ACCESSION   XP_026128292
VERSION     XP_026128292.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272507.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1283
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1283
                     /product="diacylglycerol kinase eta isoform X2"
                     /calculated_mol_wt=143446
     Region          73..218
                     /region_name="PH_DGK_type2"
                     /note="Type 2 Diacylglycerol kinase Pleckstrin homology
                     (PH) domain; cd13274"
                     /db_xref="CDD:270093"
     Region          202..287
                     /region_name="C1_DGKeta_rpt1"
                     /note="first protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20848"
                     /db_xref="CDD:410398"
     Region          298..359
                     /region_name="C1_DGKeta_rpt2"
                     /note="second protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20894"
                     /db_xref="CDD:410444"
     Region          390..512
                     /region_name="DAGKc"
                     /note="Diacylglycerol kinase catalytic domain (presumed);
                     smart00046"
                     /db_xref="CDD:214487"
     Region          <658..742
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          836..993
                     /region_name="DAGKa"
                     /note="Diacylglycerol kinase accessory domain (presumed);
                     smart00045"
                     /db_xref="CDD:214486"
     Region          1212..1275
                     /region_name="SAM_DGK-delta-eta"
                     /note="SAM domain of diacylglycerol kinase delta and eta
                     subunits; cd09507"
                     /db_xref="CDD:188906"
     Site            order(1238..1242,1248..1250,1252..1253,1256)
                     /site_type="other"
                     /note="homooligomer interface ML [polypeptide binding]"
                     /db_xref="CDD:188906"
     Site            order(1251,1255,1260..1264,1266..1267,1270)
                     /site_type="other"
                     /note="homooligomer interface EH [polypeptide binding]"
                     /db_xref="CDD:188906"
     CDS             1..1283
                     /gene="LOC113109029"
                     /coded_by="XM_026272507.1:161..4012"
                     /db_xref="GeneID:113109029"
ORIGIN      
        1 meddcqytrs paweelepek paasasglpa sgavgvsgpv ldessdsege qegpqklirk
       61 vstsgqirsk tsvkeglllk qtssfqrwkk ryfklrgrtl yyakdakagg vltrwqyrvs
      121 rsrvcwrvls vcwsgarrqp palgasgsee glvairslif devdlsdasv aesstknvnn
      181 sftvitpfrr lilcaenrke medwisslks vqsrehyeta qfnvehfsgm hnwyacshar
      241 ptfcnvcrds lsgvtshgls cevckfkahk rcavratnnc kwttlasigk diiededgia
      301 mphqwlegnl pvsakcavcd ktcgsvlrlq dwrclwckam vhtacmdlyp rkcplgqckv
      361 siipptalns idsdgfwkat cppscaspll vfvnsksgdn qgvkflrrfk qllnpaqvfd
      421 lvnggphlgl rlfqkfdnfr ilvcggdgsv gwvlseidkl nlhkqcqlgv lplgtgndla
      481 rvlgwgpscd ddtqlpqile klerastkml drwsimtyei kippkhscpa tpedtedgql
      541 qisvyedsva ahltkilnsd qhsvvisssk vlcetvkefv akvgkcyers sdsteeadal
      601 alkcailnek ldsllqtlnl eaqaltpsal ttppiveeev eeeeleeeed lseesitelk
      661 enetekgsah klfrpreqlv lranslkkal rkiieqaerv vdeqnahtde qelqsptdfr
      721 kdseeenrdn ekdedtkele alplakspcs pperrvsrst qscgsfsitp fttskenlpv
      781 lntriicpgl raglaasiag ssiiskmlla nidpfgatpf idpdldfleg ylekcvmnny
      841 fgigldakis lefnnkreeh pekcrsrtkn mmwygvlgtk ellqrtyknl eqkvqlecdg
      901 qyiplpslqg iavlnipsya ggtnfwggtk eddifcapsf ddkilevvav fgsmqmavsr
      961 viklqhhria qcrtvkitil gdegvpvqvd geawiqppgv ikiqhknraq mltrdrafen
     1021 tlkswedklk ydkpplrphl ypqhsvdlat eeeatliqmc araaedlitr iceaaenyql
     1081 leqelahavn asshainkth pkfpesltrn taievastvk alhnetelll vgrvplqldp
     1141 pheellssal qsvelelgkl aeipwlyhil qpndeednsl eygkrnsrgg mfrivpkfkk
     1201 ekaqkksspq svqrwgteev avwleqlslg eyketfirhd irgsellhle rrdlkdlgis
     1261 kvghmkrilq gtkdlakssm vdl
//
LOCUS       XP_026128293            1250 aa            linear   VRT 18-JUN-2025
DEFINITION  diacylglycerol kinase eta isoform X3 [Carassius auratus].
ACCESSION   XP_026128293
VERSION     XP_026128293.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272508.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1250
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1250
                     /product="diacylglycerol kinase eta isoform X3"
                     /calculated_mol_wt=138830
     Region          95..240
                     /region_name="PH_DGK_type2"
                     /note="Type 2 Diacylglycerol kinase Pleckstrin homology
                     (PH) domain; cd13274"
                     /db_xref="CDD:270093"
     Region          224..309
                     /region_name="C1_DGKeta_rpt1"
                     /note="first protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20848"
                     /db_xref="CDD:410398"
     Region          320..381
                     /region_name="C1_DGKeta_rpt2"
                     /note="second protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20894"
                     /db_xref="CDD:410444"
     Region          412..534
                     /region_name="DAGKc"
                     /note="Diacylglycerol kinase catalytic domain (presumed);
                     smart00046"
                     /db_xref="CDD:214487"
     Region          <680..764
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          858..1015
                     /region_name="DAGKa"
                     /note="Diacylglycerol kinase accessory domain (presumed);
                     smart00045"
                     /db_xref="CDD:214486"
     CDS             1..1250
                     /gene="LOC113109029"
                     /coded_by="XM_026272508.1:354..4106"
                     /db_xref="GeneID:113109029"
ORIGIN      
        1 mtakrtafqp lsssripaer kgaagrlhnp epcasspqep ekpaasasgl pasgavgvsg
       61 pvldessdse geqegpqkli rkvstsgqir sktsvkegll lkqtssfqrw kkryfklrgr
      121 tlyyakdaka ggvltrwqyr vsrsrvcwrv lsvcwsgarr qppalgasgs eeglvairsl
      181 ifdevdlsda svaesstknv nnsftvitpf rrlilcaenr kemedwissl ksvqsrehye
      241 taqfnvehfs gmhnwyacsh arptfcnvcr dslsgvtshg lscevckfka hkrcavratn
      301 nckwttlasi gkdiiededg iamphqwleg nlpvsakcav cdktcgsvlr lqdwrclwck
      361 amvhtacmdl yprkcplgqc kvsiipptal nsidsdgfwk atcppscasp llvfvnsksg
      421 dnqgvkflrr fkqllnpaqv fdlvnggphl glrlfqkfdn frilvcggdg svgwvlseid
      481 klnlhkqcql gvlplgtgnd larvlgwgps cdddtqlpqi leklerastk mldrwsimty
      541 eikippkhsc patpedtedg qlqisvyeds vaahltkiln sdqhsvviss skvlcetvke
      601 fvakvgkcye rssdsteead alalkcailn ekldsllqtl nleaqaltps alttppivee
      661 eveeeeleee edlseesite lkenetekgs ahklfrpreq lvlranslkk alrkiieqae
      721 rvvdeqnaht deqelqsptd frkdseeenr dnekdedtke lealplaksp cspperrvsr
      781 stqscgsfsi tpfttskenl pvlntriicp glraglaasi agssiiskml lanidpfgat
      841 pfidpdldfl egylekcvmn nyfgigldak islefnnkre ehpekcrsrt knmmwygvlg
      901 tkellqrtyk nleqkvqlec dgqyiplpsl qgiavlnips yaggtnfwgg tkeddifcap
      961 sfddkilevv avfgsmqmav srviklqhhr iaqcrtvkit ilgdegvpvq vdgeawiqpp
     1021 gvikiqhknr aqmltrdraf entlkswedk lkydkpplrp hlypqhsvdl ateeeatliq
     1081 mcaraaedli triceaaeny qlleqelaha vnasshaink thpkfpeslt rntaievast
     1141 vkalhnetel llvgrvplql dppheellss alqsvelelg klaeipwlyh ilqpndeedn
     1201 sleygkrnsr ggmfrivpkf kkekaqkkss pqsgsgdleg gsyeenspgn
//
LOCUS       XP_026128294            1234 aa            linear   VRT 18-JUN-2025
DEFINITION  diacylglycerol kinase eta isoform X4 [Carassius auratus].
ACCESSION   XP_026128294
VERSION     XP_026128294.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272509.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1234
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1234
                     /product="diacylglycerol kinase eta isoform X4"
                     /calculated_mol_wt=138078
     Region          73..169
                     /region_name="PH_DGK_type2"
                     /note="Type 2 Diacylglycerol kinase Pleckstrin homology
                     (PH) domain; cd13274"
                     /db_xref="CDD:270093"
     Region          153..238
                     /region_name="C1_DGKeta_rpt1"
                     /note="first protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20848"
                     /db_xref="CDD:410398"
     Region          249..310
                     /region_name="C1_DGKeta_rpt2"
                     /note="second protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20894"
                     /db_xref="CDD:410444"
     Region          341..463
                     /region_name="DAGKc"
                     /note="Diacylglycerol kinase catalytic domain (presumed);
                     smart00046"
                     /db_xref="CDD:214487"
     Region          <609..693
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          787..944
                     /region_name="DAGKa"
                     /note="Diacylglycerol kinase accessory domain (presumed);
                     smart00045"
                     /db_xref="CDD:214486"
     Region          1163..1226
                     /region_name="SAM_DGK-delta-eta"
                     /note="SAM domain of diacylglycerol kinase delta and eta
                     subunits; cd09507"
                     /db_xref="CDD:188906"
     Site            order(1189..1193,1199..1201,1203..1204,1207)
                     /site_type="other"
                     /note="homooligomer interface ML [polypeptide binding]"
                     /db_xref="CDD:188906"
     Site            order(1202,1206,1211..1215,1217..1218,1221)
                     /site_type="other"
                     /note="homooligomer interface EH [polypeptide binding]"
                     /db_xref="CDD:188906"
     CDS             1..1234
                     /gene="LOC113109029"
                     /coded_by="XM_026272509.1:159..3863"
                     /db_xref="GeneID:113109029"
ORIGIN      
        1 meddcqytrs paweelepek paasasglpa sgavgvsgpv ldessdsege qegpqklirk
       61 vstsgqirsk tsvkeglllk qtssfqrwkk ryfklrgrtl yyakdaksli fdevdlsdas
      121 vaesstknvn nsftvitpfr rlilcaenrk emedwisslk svqsrehyet aqfnvehfsg
      181 mhnwyacsha rptfcnvcrd slsgvtshgl scevckfkah krcavratnn ckwttlasig
      241 kdiiededgi amphqwlegn lpvsakcavc dktcgsvlrl qdwrclwcka mvhtacmdly
      301 prkcplgqck vsiipptaln sidsdgfwka tcppscaspl lvfvnsksgd nqgvkflrrf
      361 kqllnpaqvf dlvnggphlg lrlfqkfdnf rilvcggdgs vgwvlseidk lnlhkqcqlg
      421 vlplgtgndl arvlgwgpsc dddtqlpqil eklerastkm ldrwsimtye ikippkhscp
      481 atpedtedgq lqisvyedsv aahltkilns dqhsvvisss kvlcetvkef vakvgkcyer
      541 ssdsteeada lalkcailne kldsllqtln leaqaltpsa lttppiveee veeeeleeee
      601 dlseesitel kenetekgsa hklfrpreql vlranslkka lrkiieqaer vvdeqnahtd
      661 eqelqsptdf rkdseeenrd nekdedtkel ealplakspc spperrvsrs tqscgsfsit
      721 pfttskenlp vlntriicpg lraglaasia gssiiskmll anidpfgatp fidpdldfle
      781 gylekcvmnn yfgigldaki slefnnkree hpekcrsrtk nmmwygvlgt kellqrtykn
      841 leqkvqlecd gqyiplpslq giavlnipsy aggtnfwggt keddifcaps fddkilevva
      901 vfgsmqmavs rviklqhhri aqcrtvkiti lgdegvpvqv dgeawiqppg vikiqhknra
      961 qmltrdrafe ntlkswedkl kydkpplrph lypqhsvdla teeeatliqm caraaedlit
     1021 riceaaenyq lleqelahav nasshainkt hpkfpesltr ntaievastv kalhnetell
     1081 lvgrvplqld ppheellssa lqsvelelgk laeipwlyhi lqpndeedns leygkrnsrg
     1141 gmfrivpkfk kekaqkkssp qsvqrwgtee vavwleqlsl geyketfirh dirgsellhl
     1201 errdlkdlgi skvghmkril qgtkdlakss mvdl
//
LOCUS       XP_026128295            1083 aa            linear   VRT 18-JUN-2025
DEFINITION  diacylglycerol kinase eta isoform X5 [Carassius auratus].
ACCESSION   XP_026128295
VERSION     XP_026128295.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272510.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1083
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1083
                     /product="diacylglycerol kinase eta isoform X5"
                     /calculated_mol_wt=121343
     Region          2..87
                     /region_name="C1_DGKeta_rpt1"
                     /note="first protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20848"
                     /db_xref="CDD:410398"
     Region          98..159
                     /region_name="C1_DGKeta_rpt2"
                     /note="second protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20894"
                     /db_xref="CDD:410444"
     Region          190..312
                     /region_name="DAGKc"
                     /note="Diacylglycerol kinase catalytic domain (presumed);
                     smart00046"
                     /db_xref="CDD:214487"
     Region          <458..542
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          636..793
                     /region_name="DAGKa"
                     /note="Diacylglycerol kinase accessory domain (presumed);
                     smart00045"
                     /db_xref="CDD:214486"
     Region          1012..1075
                     /region_name="SAM_DGK-delta-eta"
                     /note="SAM domain of diacylglycerol kinase delta and eta
                     subunits; cd09507"
                     /db_xref="CDD:188906"
     Site            order(1038..1042,1048..1050,1052..1053,1056)
                     /site_type="other"
                     /note="homooligomer interface ML [polypeptide binding]"
                     /db_xref="CDD:188906"
     Site            order(1051,1055,1060..1064,1066..1067,1070)
                     /site_type="other"
                     /note="homooligomer interface EH [polypeptide binding]"
                     /db_xref="CDD:188906"
     CDS             1..1083
                     /gene="LOC113109029"
                     /coded_by="XM_026272510.1:597..3848"
                     /db_xref="GeneID:113109029"
ORIGIN      
        1 medwisslks vqsrehyeta qfnvehfsgm hnwyacshar ptfcnvcrds lsgvtshgls
       61 cevckfkahk rcavratnnc kwttlasigk diiededgia mphqwlegnl pvsakcavcd
      121 ktcgsvlrlq dwrclwckam vhtacmdlyp rkcplgqckv siipptalns idsdgfwkat
      181 cppscaspll vfvnsksgdn qgvkflrrfk qllnpaqvfd lvnggphlgl rlfqkfdnfr
      241 ilvcggdgsv gwvlseidkl nlhkqcqlgv lplgtgndla rvlgwgpscd ddtqlpqile
      301 klerastkml drwsimtyei kippkhscpa tpedtedgql qisvyedsva ahltkilnsd
      361 qhsvvisssk vlcetvkefv akvgkcyers sdsteeadal alkcailnek ldsllqtlnl
      421 eaqaltpsal ttppiveeev eeeeleeeed lseesitelk enetekgsah klfrpreqlv
      481 lranslkkal rkiieqaerv vdeqnahtde qelqsptdfr kdseeenrdn ekdedtkele
      541 alplakspcs pperrvsrst qscgsfsitp fttskenlpv lntriicpgl raglaasiag
      601 ssiiskmlla nidpfgatpf idpdldfleg ylekcvmnny fgigldakis lefnnkreeh
      661 pekcrsrtkn mmwygvlgtk ellqrtyknl eqkvqlecdg qyiplpslqg iavlnipsya
      721 ggtnfwggtk eddifcapsf ddkilevvav fgsmqmavsr viklqhhria qcrtvkitil
      781 gdegvpvqvd geawiqppgv ikiqhknraq mltrdrafen tlkswedklk ydkpplrphl
      841 ypqhsvdlat eeeatliqmc araaedlitr iceaaenyql leqelahavn asshainkth
      901 pkfpesltrn taievastvk alhnetelll vgrvplqldp pheellssal qsvelelgkl
      961 aeipwlyhil qpndeednsl eygkrnsrgg mfrivpkfkk ekaqkksspq svqrwgteev
     1021 avwleqlslg eyketfirhd irgsellhle rrdlkdlgis kvghmkrilq gtkdlakssm
     1081 vdl
//
LOCUS       XP_026128297            1054 aa            linear   VRT 18-JUN-2025
DEFINITION  diacylglycerol kinase eta isoform X6 [Carassius auratus].
ACCESSION   XP_026128297
VERSION     XP_026128297.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272512.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1054
                     /product="diacylglycerol kinase eta isoform X6"
                     /calculated_mol_wt=117918
     Region          <1..62
                     /region_name="C1"
                     /note="protein kinase C conserved region 1 (C1 domain)
                     superfamily; cl00040"
                     /db_xref="CDD:412127"
     Region          69..130
                     /region_name="C1_DGKeta_rpt2"
                     /note="second protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20894"
                     /db_xref="CDD:410444"
     Region          161..283
                     /region_name="DAGKc"
                     /note="Diacylglycerol kinase catalytic domain (presumed);
                     smart00046"
                     /db_xref="CDD:214487"
     Region          <429..513
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          607..764
                     /region_name="DAGKa"
                     /note="Diacylglycerol kinase accessory domain (presumed);
                     smart00045"
                     /db_xref="CDD:214486"
     Region          983..1046
                     /region_name="SAM_DGK-delta-eta"
                     /note="SAM domain of diacylglycerol kinase delta and eta
                     subunits; cd09507"
                     /db_xref="CDD:188906"
     Site            order(1009..1013,1019..1021,1023..1024,1027)
                     /site_type="other"
                     /note="homooligomer interface ML [polypeptide binding]"
                     /db_xref="CDD:188906"
     Site            order(1022,1026,1031..1035,1037..1038,1041)
                     /site_type="other"
                     /note="homooligomer interface EH [polypeptide binding]"
                     /db_xref="CDD:188906"
     CDS             1..1054
                     /gene="LOC113109029"
                     /coded_by="XM_026272512.1:108..3272"
                     /db_xref="GeneID:113109029"
ORIGIN      
        1 mhnwyacsha rptfcnvcrd slsgvtshgl scevckfkah krcavratnn ckwttlasig
       61 kdiiededgi amphqwlegn lpvsakcavc dktcgsvlrl qdwrclwcka mvhtacmdly
      121 prkcplgqck vsiipptaln sidsdgfwka tcppscaspl lvfvnsksgd nqgvkflrrf
      181 kqllnpaqvf dlvnggphlg lrlfqkfdnf rilvcggdgs vgwvlseidk lnlhkqcqlg
      241 vlplgtgndl arvlgwgpsc dddtqlpqil eklerastkm ldrwsimtye ikippkhscp
      301 atpedtedgq lqisvyedsv aahltkilns dqhsvvisss kvlcetvkef vakvgkcyer
      361 ssdsteeada lalkcailne kldsllqtln leaqaltpsa lttppiveee veeeeleeee
      421 dlseesitel kenetekgsa hklfrpreql vlranslkka lrkiieqaer vvdeqnahtd
      481 eqelqsptdf rkdseeenrd nekdedtkel ealplakspc spperrvsrs tqscgsfsit
      541 pfttskenlp vlntriicpg lraglaasia gssiiskmll anidpfgatp fidpdldfle
      601 gylekcvmnn yfgigldaki slefnnkree hpekcrsrtk nmmwygvlgt kellqrtykn
      661 leqkvqlecd gqyiplpslq giavlnipsy aggtnfwggt keddifcaps fddkilevva
      721 vfgsmqmavs rviklqhhri aqcrtvkiti lgdegvpvqv dgeawiqppg vikiqhknra
      781 qmltrdrafe ntlkswedkl kydkpplrph lypqhsvdla teeeatliqm caraaedlit
      841 riceaaenyq lleqelahav nasshainkt hpkfpesltr ntaievastv kalhnetell
      901 lvgrvplqld ppheellssa lqsvelelgk laeipwlyhi lqpndeedns leygkrnsrg
      961 gmfrivpkfk kekaqkkssp qsvqrwgtee vavwleqlsl geyketfirh dirgsellhl
     1021 errdlkdlgi skvghmkril qgtkdlakss mvdl
//
LOCUS       XP_026128298            1179 aa            linear   VRT 18-JUN-2025
DEFINITION  diacylglycerol kinase eta isoform X7 [Carassius auratus].
ACCESSION   XP_026128298
VERSION     XP_026128298.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272513.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1179
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1179
                     /product="diacylglycerol kinase eta isoform X7"
                     /calculated_mol_wt=131386
     Region          73..169
                     /region_name="PH_DGK_type2"
                     /note="Type 2 Diacylglycerol kinase Pleckstrin homology
                     (PH) domain; cd13274"
                     /db_xref="CDD:270093"
     Region          153..238
                     /region_name="C1_DGKeta_rpt1"
                     /note="first protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20848"
                     /db_xref="CDD:410398"
     Region          249..310
                     /region_name="C1_DGKeta_rpt2"
                     /note="second protein kinase C conserved region 1 (C1
                     domain) found in diacylglycerol kinase eta (DAG kinase
                     eta) and similar proteins; cd20894"
                     /db_xref="CDD:410444"
     Region          341..463
                     /region_name="DAGKc"
                     /note="Diacylglycerol kinase catalytic domain (presumed);
                     smart00046"
                     /db_xref="CDD:214487"
     Region          <609..693
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          787..944
                     /region_name="DAGKa"
                     /note="Diacylglycerol kinase accessory domain (presumed);
                     smart00045"
                     /db_xref="CDD:214486"
     CDS             1..1179
                     /gene="LOC113109029"
                     /coded_by="XM_026272513.1:159..3698"
                     /db_xref="GeneID:113109029"
ORIGIN      
        1 meddcqytrs paweelepek paasasglpa sgavgvsgpv ldessdsege qegpqklirk
       61 vstsgqirsk tsvkeglllk qtssfqrwkk ryfklrgrtl yyakdaksli fdevdlsdas
      121 vaesstknvn nsftvitpfr rlilcaenrk emedwisslk svqsrehyet aqfnvehfsg
      181 mhnwyacsha rptfcnvcrd slsgvtshgl scevckfkah krcavratnn ckwttlasig
      241 kdiiededgi amphqwlegn lpvsakcavc dktcgsvlrl qdwrclwcka mvhtacmdly
      301 prkcplgqck vsiipptaln sidsdgfwka tcppscaspl lvfvnsksgd nqgvkflrrf
      361 kqllnpaqvf dlvnggphlg lrlfqkfdnf rilvcggdgs vgwvlseidk lnlhkqcqlg
      421 vlplgtgndl arvlgwgpsc dddtqlpqil eklerastkm ldrwsimtye ikippkhscp
      481 atpedtedgq lqisvyedsv aahltkilns dqhsvvisss kvlcetvkef vakvgkcyer
      541 ssdsteeada lalkcailne kldsllqtln leaqaltpsa lttppiveee veeeeleeee
      601 dlseesitel kenetekgsa hklfrpreql vlranslkka lrkiieqaer vvdeqnahtd
      661 eqelqsptdf rkdseeenrd nekdedtkel ealplakspc spperrvsrs tqscgsfsit
      721 pfttskenlp vlntriicpg lraglaasia gssiiskmll anidpfgatp fidpdldfle
      781 gylekcvmnn yfgigldaki slefnnkree hpekcrsrtk nmmwygvlgt kellqrtykn
      841 leqkvqlecd gqyiplpslq giavlnipsy aggtnfwggt keddifcaps fddkilevva
      901 vfgsmqmavs rviklqhhri aqcrtvkiti lgdegvpvqv dgeawiqppg vikiqhknra
      961 qmltrdrafe ntlkswedkl kydkpplrph lypqhsvdla teeeatliqm caraaedlit
     1021 riceaaenyq lleqelahav nasshainkt hpkfpesltr ntaievastv kalhnetell
     1081 lvgrvplqld ppheellssa lqsvelelgk laeipwlyhi lqpndeedns leygkrnsrg
     1141 gmfrivpkfk kekaqkkssp qsgsgdlegg syeenspgn
//
LOCUS       XP_026128299             127 aa            linear   VRT 18-JUN-2025
DEFINITION  regulator of cell cycle RGCC isoform X1 [Carassius auratus].
ACCESSION   XP_026128299
VERSION     XP_026128299.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272514.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..127
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..127
                     /product="regulator of cell cycle RGCC isoform X1"
                     /calculated_mol_wt=14012
     Region          1..125
                     /region_name="RGCC"
                     /note="Response gene to complement 32 protein family;
                     pfam15151"
                     /db_xref="CDD:464535"
     CDS             1..127
                     /gene="rgcc"
                     /coded_by="XM_026272514.1:129..512"
                     /db_xref="GeneID:113109030"
ORIGIN      
        1 mkspkiksqs ksfleedddl savlcefdav iedfsspvek rhfrydehlk tvkrrssasv
       61 sdsgisdses aeslnrnsfs fsdeklnsps vfstnsplvt spkpklgdtk eledfiadld
      121 rtlaskc
//
LOCUS       XP_026128300             126 aa            linear   VRT 18-JUN-2025
DEFINITION  regulator of cell cycle RGCC isoform X2 [Carassius auratus].
ACCESSION   XP_026128300
VERSION     XP_026128300.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272515.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..126
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..126
                     /product="regulator of cell cycle RGCC isoform X2"
                     /calculated_mol_wt=13912
     Region          1..126
                     /region_name="RGCC"
                     /note="Response gene to complement 32 protein family;
                     pfam15151"
                     /db_xref="CDD:464535"
     CDS             1..126
                     /gene="rgcc"
                     /coded_by="XM_026272515.1:129..509"
                     /db_xref="GeneID:113109030"
ORIGIN      
        1 mkspkiksqs ksfleedddl savlcefdav iedfsspvek rhfrydehlk tvkrrssasv
       61 sdsgisdses aeslnrnsfs fsdeklnsps vfstnsplvt spkpklgdtk eledfiadld
      121 rtlasm
//
LOCUS       XP_026128301             233 aa            linear   VRT 18-JUN-2025
DEFINITION  ras-related protein Rab-33B [Carassius auratus].
ACCESSION   XP_026128301
VERSION     XP_026128301.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272516.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..233
                     /product="ras-related protein Rab-33B"
                     /calculated_mol_wt=26407
     Region          35..204
                     /region_name="Rab33B_Rab33A"
                     /note="Rab GTPase family 33 includes Rab33A and Rab33B;
                     cd04115"
                     /db_xref="CDD:133315"
     Site            37..38
                     /site_type="other"
                     /note="Rab subfamily motif 1 (RabSF1)"
                     /db_xref="CDD:133315"
     Site            43..50
                     /site_type="other"
                     /note="G1 box"
                     /db_xref="CDD:133315"
     Site            order(45..51,61,65,68,94,151..152,154..155,181..183)
                     /site_type="other"
                     /note="GTP/Mg2+ binding site [chemical binding]"
                     /db_xref="CDD:133315"
     Site            order(51..62,66..67)
                     /site_type="other"
                     /note="Rab subfamily motif 2 (RabSF2)"
                     /db_xref="CDD:133315"
     Site            order(61,66..74)
                     /site_type="other"
                     /note="Switch I region"
                     /db_xref="CDD:133315"
     Site            order(66,70..77,84,86)
                     /site_type="other"
                     /note="putative GEF interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:133315"
     Site            68
                     /site_type="other"
                     /note="G2 box"
                     /db_xref="CDD:133315"
     Site            order(69,71..73,88,90,97..98,102,106,108..111,202)
                     /site_type="active"
                     /note="putative effector interaction site [active]"
                     /db_xref="CDD:133315"
     Site            order(69..70,72,90..91,98,101,103..105)
                     /site_type="other"
                     /note="putative GDI interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:133315"
     Site            69..73
                     /site_type="other"
                     /note="Rab family motif 1 (RabF1)"
                     /db_xref="CDD:133315"
     Site            86..90
                     /site_type="other"
                     /note="Rab family motif 2 (RabF2)"
                     /db_xref="CDD:133315"
     Site            91..94
                     /site_type="other"
                     /note="G3 box"
                     /db_xref="CDD:133315"
     Site            order(94,96..106)
                     /site_type="other"
                     /note="Switch II region"
                     /db_xref="CDD:133315"
     Site            97..102
                     /site_type="other"
                     /note="Rab family motif 3 (RabF3)"
                     /db_xref="CDD:133315"
     Site            106..110
                     /site_type="other"
                     /note="Rab family motif 4 (RabF4)"
                     /db_xref="CDD:133315"
     Site            115..120
                     /site_type="other"
                     /note="Rab family motif 5 (RabF5)"
                     /db_xref="CDD:133315"
     Site            144..148
                     /site_type="other"
                     /note="Rab subfamily motif 3 (RabSF3)"
                     /db_xref="CDD:133315"
     Site            151..154
                     /site_type="other"
                     /note="G4 box"
                     /db_xref="CDD:133315"
     Site            181..183
                     /site_type="other"
                     /note="G5 box"
                     /db_xref="CDD:133315"
     Site            200..204
                     /site_type="other"
                     /note="Rab subfamily motif 4 (RabSF4)"
                     /db_xref="CDD:133315"
     CDS             1..233
                     /gene="LOC113109031"
                     /coded_by="XM_026272516.1:12..713"
                     /db_xref="GeneID:113109031"
ORIGIN      
        1 maienttgnn dfstiytrdg landscpdhd sprervfkii vigdsnvgkt cltyrfcggk
       61 flqnpeatig vdfrertlhl dgeniklqiw dtagqerfrk smvehyyrnv haiifvydvt
      121 slasfeslpe wieecsrhsv ppmvprilvg nkcdlrgare vstflaqrla dsynfplfet
      181 sardpaekeh vdaifltlay rlknhkplrl kqpsesnflq laggqeekts clc
//
LOCUS       XP_026128302             590 aa            linear   VRT 18-JUN-2025
DEFINITION  SLAIN motif-containing protein 1a isoform X1 [Carassius auratus].
ACCESSION   XP_026128302
VERSION     XP_026128302.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272517.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..590
                     /product="SLAIN motif-containing protein 1a isoform X1"
                     /calculated_mol_wt=64594
     Region          132..590
                     /region_name="SLAIN"
                     /note="SLAIN motif-containing family; pfam15301"
                     /db_xref="CDD:464627"
     CDS             1..590
                     /gene="slain1a"
                     /coded_by="XM_026272517.1:81..1853"
                     /db_xref="GeneID:113109032"
ORIGIN      
        1 mkrasrlkal rvwahrtmad vngnskimna elevkklqel vrklerqneq lrtranaann
       61 ctsggrlgpd tgsyclsssc spsfgspeeh ypyfhpqsvt gadeedatvl deveildlrv
      121 vlpidgesdy iwlyvspkak lfphlllspl qwcrhvldnp rpevelakrs lcykldqakr
      181 wrgvlssstl yspvdelsal sscskpytkp alteqtadpp spnhqktltg rncsslners
      241 ptflyhtatq gnshhqrpls pqssidsdls vseleddsis msyklqdmtd vevmarlqee
      301 slrqeyastt atatrrsasf svhtgarrsm rseaeleeee eydqlsapqp rlfrtssmqr
      361 stshsqslss mrecrrspst pqylsspsyq qlhmpnlsss tapetqsyra htdklrrsmp
      421 nllrapsips visvpgvpap aahvatssss lsllrnsqsf dshsglakiq taipcpgqlq
      481 qrvqsvgnfs trpplkatay vsptiqsatt mpssvslgsi psssssiplp skpsapsstr
      541 salprpasfv gtsgvsrski gqpmrslltp pksvsalsal rdgswrdgcy
//
LOCUS       XP_026128303             589 aa            linear   VRT 18-JUN-2025
DEFINITION  SLAIN motif-containing protein 1a isoform X2 [Carassius auratus].
ACCESSION   XP_026128303
VERSION     XP_026128303.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272518.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..589
                     /product="SLAIN motif-containing protein 1a isoform X2"
                     /calculated_mol_wt=64523
     Region          132..589
                     /region_name="SLAIN"
                     /note="SLAIN motif-containing family; pfam15301"
                     /db_xref="CDD:464627"
     CDS             1..589
                     /gene="slain1a"
                     /coded_by="XM_026272518.1:81..1850"
                     /db_xref="GeneID:113109032"
ORIGIN      
        1 mkrasrlkal rvwahrtmad vngnskimna elevkklqel vrklerqneq lrtranaann
       61 ctsggrlgpd tgsyclsssc spsfgspeeh ypyfhpqsvt gadeedatvl deveildlrv
      121 vlpidgesdy iwlyvspkak lfphlllspl qwcrhvldnp rpevelakrs lcykldqakr
      181 wrgvlssstl yspvdelsal sscskpytkp alteqtdpps pnhqktltgr ncsslnersp
      241 tflyhtatqg nshhqrplsp qssidsdlsv seleddsism syklqdmtdv evmarlqees
      301 lrqeyastta tatrrsasfs vhtgarrsmr seaeleeeee ydqlsapqpr lfrtssmqrs
      361 tshsqslssm recrrspstp qylsspsyqq lhmpnlssst apetqsyrah tdklrrsmpn
      421 llrapsipsv isvpgvpapa ahvatssssl sllrnsqsfd shsglakiqt aipcpgqlqq
      481 rvqsvgnfst rpplkatayv sptiqsattm pssvslgsip sssssiplps kpsapsstrs
      541 alprpasfvg tsgvsrskig qpmrslltpp ksvsalsalr dgswrdgcy
//
LOCUS       XP_026128304             588 aa            linear   VRT 18-JUN-2025
DEFINITION  SLAIN motif-containing protein 1a isoform X3 [Carassius auratus].
ACCESSION   XP_026128304
VERSION     XP_026128304.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272519.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..588
                     /product="SLAIN motif-containing protein 1a isoform X3"
                     /calculated_mol_wt=64214
     Region          130..588
                     /region_name="SLAIN"
                     /note="SLAIN motif-containing family; pfam15301"
                     /db_xref="CDD:464627"
     CDS             1..588
                     /gene="slain1a"
                     /coded_by="XM_026272519.1:128..1894"
                     /db_xref="GeneID:113109032"
ORIGIN      
        1 mlfssmdgll fnpqtmadvn gnskimnael evkklqelvr klerqneqlr tranaannct
       61 sggrlgpdtg syclssscsp sfgspeehyp yfhpqsvtga deedatvlde veildlrvvl
      121 pidgesdyiw lyvspkaklf phlllsplqw crhvldnprp evelakrslc ykldqakrwr
      181 gvlssstlys pvdelsalss cskpytkpal teqtadppsp nhqktltgrn csslnerspt
      241 flyhtatqgn shhqrplspq ssidsdlsvs eleddsisms yklqdmtdve vmarlqeesl
      301 rqeyasttat atrrsasfsv htgarrsmrs eaeleeeeey dqlsapqprl frtssmqrst
      361 shsqslssmr ecrrspstpq ylsspsyqql hmpnlsssta petqsyraht dklrrsmpnl
      421 lrapsipsvi svpgvpapaa hvatssssls llrnsqsfds hsglakiqta ipcpgqlqqr
      481 vqsvgnfstr pplkatayvs ptiqsattmp ssvslgsips ssssiplpsk psapsstrsa
      541 lprpasfvgt sgvsrskigq pmrslltppk svsalsalrd gswrdgcy
//
LOCUS       XP_026128305             573 aa            linear   VRT 18-JUN-2025
DEFINITION  SLAIN motif-containing protein 1a isoform X4 [Carassius auratus].
ACCESSION   XP_026128305
VERSION     XP_026128305.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272520.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..573
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..573
                     /product="SLAIN motif-containing protein 1a isoform X4"
                     /calculated_mol_wt=62531
     Region          115..573
                     /region_name="SLAIN"
                     /note="SLAIN motif-containing family; pfam15301"
                     /db_xref="CDD:464627"
     CDS             1..573
                     /gene="slain1a"
                     /coded_by="XM_026272520.1:113..1834"
                     /db_xref="GeneID:113109032"
ORIGIN      
        1 madvngnski mnaelevkkl qelvrklerq neqlrtrana annctsggrl gpdtgsycls
       61 sscspsfgsp eehypyfhpq svtgadeeda tvldeveild lrvvlpidge sdyiwlyvsp
      121 kaklfphlll splqwcrhvl dnprpevela krslcykldq akrwrgvlss stlyspvdel
      181 salsscskpy tkpalteqta dppspnhqkt ltgrncssln ersptflyht atqgnshhqr
      241 plspqssids dlsvseledd sismsyklqd mtdvevmarl qeeslrqeya sttatatrrs
      301 asfsvhtgar rsmrseaele eeeeydqlsa pqprlfrtss mqrstshsqs lssmrecrrs
      361 pstpqylssp syqqlhmpnl ssstapetqs yrahtdklrr smpnllraps ipsvisvpgv
      421 papaahvats ssslsllrns qsfdshsgla kiqtaipcpg qlqqrvqsvg nfstrpplka
      481 tayvsptiqs attmpssvsl gsipsssssi plpskpsaps strsalprpa sfvgtsgvsr
      541 skigqpmrsl ltppksvsal salrdgswrd gcy
//
LOCUS       XP_026128306             551 aa            linear   VRT 18-JUN-2025
DEFINITION  SLAIN motif-containing protein 1a isoform X5 [Carassius auratus].
ACCESSION   XP_026128306
VERSION     XP_026128306.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272521.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..551
                     /product="SLAIN motif-containing protein 1a isoform X5"
                     /calculated_mol_wt=60353
     Region          132..551
                     /region_name="SLAIN"
                     /note="SLAIN motif-containing family; pfam15301"
                     /db_xref="CDD:464627"
     CDS             1..551
                     /gene="slain1a"
                     /coded_by="XM_026272521.1:81..1736"
                     /db_xref="GeneID:113109032"
ORIGIN      
        1 mkrasrlkal rvwahrtmad vngnskimna elevkklqel vrklerqneq lrtranaann
       61 ctsggrlgpd tgsyclsssc spsfgspeeh ypyfhpqsvt gadeedatvl deveildlrv
      121 vlpidgesdy iwlyvspkak lfphlllspl qwcrhvldnp rpevelakrs lcykldqadp
      181 pspnhqktlt grncsslner sptflyhtat qgnshhqrpl spqssidsdl svseleddsi
      241 smsyklqdmt dvevmarlqe eslrqeyast tatatrrsas fsvhtgarrs mrseaeleee
      301 eeydqlsapq prlfrtssmq rstshsqsls smrecrrsps tpqylsspsy qqlhmpnlss
      361 stapetqsyr ahtdklrrsm pnllrapsip svisvpgvpa paahvatsss slsllrnsqs
      421 fdshsglaki qtaipcpgql qqrvqsvgnf strpplkata yvsptiqsat tmpssvslgs
      481 ipsssssipl pskpsapsst rsalprpasf vgtsgvsrsk igqpmrsllt ppksvsalsa
      541 lrdgswrdgc y
//
LOCUS       XP_026128307             550 aa            linear   VRT 18-JUN-2025
DEFINITION  SLAIN motif-containing protein 1a isoform X6 [Carassius auratus].
ACCESSION   XP_026128307
VERSION     XP_026128307.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272522.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..550
                     /product="SLAIN motif-containing protein 1a isoform X6"
                     /calculated_mol_wt=60282
     Region          132..550
                     /region_name="SLAIN"
                     /note="SLAIN motif-containing family; pfam15301"
                     /db_xref="CDD:464627"
     CDS             1..550
                     /gene="slain1a"
                     /coded_by="XM_026272522.1:81..1733"
                     /db_xref="GeneID:113109032"
ORIGIN      
        1 mkrasrlkal rvwahrtmad vngnskimna elevkklqel vrklerqneq lrtranaann
       61 ctsggrlgpd tgsyclsssc spsfgspeeh ypyfhpqsvt gadeedatvl deveildlrv
      121 vlpidgesdy iwlyvspkak lfphlllspl qwcrhvldnp rpevelakrs lcykldqdpp
      181 spnhqktltg rncsslners ptflyhtatq gnshhqrpls pqssidsdls vseleddsis
      241 msyklqdmtd vevmarlqee slrqeyastt atatrrsasf svhtgarrsm rseaeleeee
      301 eydqlsapqp rlfrtssmqr stshsqslss mrecrrspst pqylsspsyq qlhmpnlsss
      361 tapetqsyra htdklrrsmp nllrapsips visvpgvpap aahvatssss lsllrnsqsf
      421 dshsglakiq taipcpgqlq qrvqsvgnfs trpplkatay vsptiqsatt mpssvslgsi
      481 psssssiplp skpsapsstr salprpasfv gtsgvsrski gqpmrslltp pksvsalsal
      541 rdgswrdgcy
//
LOCUS       XP_026128308             565 aa            linear   VRT 18-JUN-2025
DEFINITION  mucin-5AC-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128308
VERSION     XP_026128308.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272523.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..565
                     /product="mucin-5AC-like isoform X1"
                     /calculated_mol_wt=62154
     Region          498..556
                     /region_name="LIM"
                     /note="LIM is a small protein-protein interaction domain,
                     containing two zinc fingers; cd08368"
                     /db_xref="CDD:259829"
     Site            order(498,501,521,524,527,530,552,555)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:259829"
     CDS             1..565
                     /gene="LOC113109034"
                     /coded_by="XM_026272523.1:198..1895"
                     /db_xref="GeneID:113109034"
ORIGIN      
        1 msftpksysk pqtvttsstr siktvddgkk ksllkdnswi ktnvneneqv eresnfgrsv
       61 lsryksnenl vspqdktskt esktstvtts sgtsvqalsk rfggsqdkln etrttgtktt
      121 vkteprrsst ssttttikdg tkitettvtt tsqdvvksst ksetlsdkdl adlntrssgk
      181 yktevitvks skdtvdgpts pvktstsikt ytkedvspak rtsysvrstk stedhlfdtl
      241 iptsvktant kpdhsdykte vvtvktskdi sdvptspvkt ttsiktytke dvsptkttsy
      301 stksdyktev vtvksskdii dlptspvktt tsiktytned vsptkttsys tksdyktevv
      361 tvksskdisd vptspvkttt siktytedvs ptkttsysvr stkstedqlf dtlipssiks
      421 antkydssre dvsvsksirt vystnerdew stvtspsytr tsytesrpvd ylsdtlsskt
      481 tttvytsper vvsgkdictv chknmytdek ivlddmninc hascfkcgvc hlslghlkag
      541 dslwvyrrai hcescfgvtk gkwlr
//
LOCUS       XP_026128309             565 aa            linear   VRT 18-JUN-2025
DEFINITION  mucin-5AC-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128309
VERSION     XP_026128309.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272524.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..565
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..565
                     /product="mucin-5AC-like isoform X1"
                     /calculated_mol_wt=62154
     Region          498..556
                     /region_name="LIM"
                     /note="LIM is a small protein-protein interaction domain,
                     containing two zinc fingers; cd08368"
                     /db_xref="CDD:259829"
     Site            order(498,501,521,524,527,530,552,555)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:259829"
     CDS             1..565
                     /gene="LOC113109034"
                     /coded_by="XM_026272524.1:111..1808"
                     /db_xref="GeneID:113109034"
ORIGIN      
        1 msftpksysk pqtvttsstr siktvddgkk ksllkdnswi ktnvneneqv eresnfgrsv
       61 lsryksnenl vspqdktskt esktstvtts sgtsvqalsk rfggsqdkln etrttgtktt
      121 vkteprrsst ssttttikdg tkitettvtt tsqdvvksst ksetlsdkdl adlntrssgk
      181 yktevitvks skdtvdgpts pvktstsikt ytkedvspak rtsysvrstk stedhlfdtl
      241 iptsvktant kpdhsdykte vvtvktskdi sdvptspvkt ttsiktytke dvsptkttsy
      301 stksdyktev vtvksskdii dlptspvktt tsiktytned vsptkttsys tksdyktevv
      361 tvksskdisd vptspvkttt siktytedvs ptkttsysvr stkstedqlf dtlipssiks
      421 antkydssre dvsvsksirt vystnerdew stvtspsytr tsytesrpvd ylsdtlsskt
      481 tttvytsper vvsgkdictv chknmytdek ivlddmninc hascfkcgvc hlslghlkag
      541 dslwvyrrai hcescfgvtk gkwlr
//
LOCUS       XP_026128312             516 aa            linear   VRT 18-JUN-2025
DEFINITION  sciellin-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128312
VERSION     XP_026128312.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272527.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..516
                     /product="sciellin-like isoform X2"
                     /calculated_mol_wt=56785
     Region          449..507
                     /region_name="LIM"
                     /note="LIM is a small protein-protein interaction domain,
                     containing two zinc fingers; cd08368"
                     /db_xref="CDD:259829"
     Site            order(449,452,472,475,478,481,503,506)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:259829"
     CDS             1..516
                     /gene="LOC113109034"
                     /coded_by="XM_026272527.1:197..1747"
                     /db_xref="GeneID:113109034"
ORIGIN      
        1 msftpksysk pqtvttsstr siktvddgkk ksllkdnswi ktnvneneqv eresnfgrsv
       61 lsryksnenl vspqdktskt esktstvtts sgtsvqalsk rfggsqdkln etrttgtktt
      121 vkteprrsst ssttttikdg tkitettvtt tsqdvvksst ksetlsdkdl adlntrssgk
      181 yktevitvks skdtvdgpts pvktstsikt ytkedvspak rtsysvrstk stedhlfdtl
      241 iptsvktant kpdhsdykte vvtvktskdi sdvptspvkt ttsiktytke dvsptkttsy
      301 stksdyktev vtvksskdis dvptspvktt tsiktytedv sptkttsysv rstkstedql
      361 fdtlipssik santkydssr edvsvsksir tvystnerde wstvtspsyt rtsytesrpv
      421 dylsdtlssk ttttvytspe rvvsgkdict vchknmytde kivlddmnin chascfkcgv
      481 chlslghlka gdslwvyrra ihcescfgvt kgkwlr
//
LOCUS       XP_026128313             467 aa            linear   VRT 18-JUN-2025
DEFINITION  sciellin-like isoform X3 [Carassius auratus].
ACCESSION   XP_026128313
VERSION     XP_026128313.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272528.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..467
                     /product="sciellin-like isoform X3"
                     /calculated_mol_wt=51442
     Region          400..458
                     /region_name="LIM"
                     /note="LIM is a small protein-protein interaction domain,
                     containing two zinc fingers; cd08368"
                     /db_xref="CDD:259829"
     Site            order(400,403,423,426,429,432,454,457)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:259829"
     CDS             1..467
                     /gene="LOC113109034"
                     /coded_by="XM_026272528.1:197..1600"
                     /db_xref="GeneID:113109034"
ORIGIN      
        1 msftpksysk pqtvttsstr siktvddgkk ksllkdnswi ktnvneneqv eresnfgrsv
       61 lsryksnenl vspqdktskt esktstvtts sgtsvqalsk rfggsqdkln etrttgtktt
      121 vkteprrsst ssttttikdg tkitettvtt tsqdvvksst ksetlsdkdl adlntrssgk
      181 yktevitvks skdtvdgpts pvktstsikt ytkedvspak rtsysvrstk stedhlfdtl
      241 iptsvktant kpdhsdykte vvtvktskdi sdvptspvkt ttsiktyted vsptkttsys
      301 vrstkstedq lfdtlipssi ksantkydss redvsvsksi rtvystnerd ewstvtspsy
      361 trtsytesrp vdylsdtlss kttttvytsp ervvsgkdic tvchknmytd ekivlddmni
      421 nchascfkcg vchlslghlk agdslwvyrr aihcescfgv tkgkwlr
//
LOCUS       XP_026128314            4769 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X1 [Carassius auratus].
ACCESSION   XP_026128314
VERSION     XP_026128314.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272529.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4769
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4769
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X1"
                     /calculated_mol_wt=522333
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4350..4398
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4516..4570
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4769
                     /gene="LOC113109035"
                     /coded_by="XM_026272529.1:449..14758"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdnifsts qgvrdidfls wttltcfpqe grsnlddygk
     2581 etsghpsqda nvgdlgtgqg ggpglykvvk tgpsghnirs cpnlrgipig mlvlgnkvka
     2641 vgevinpegt wvqldknsvv efcesddgea wslardrggn qylrheeeqv ilehgaqtpp
     2701 pspfsvqafn rgmdssgaqg fdyginnkgd rlsailnsiq sgpflptpsi feqaakppss
     2761 lvhspfvfgq slsqqpqphp qlpnassrsl asrervhksn atgpgttlss lvlrqkgdrd
     2821 nlasrsmspg skhrqesrss ktdshssrsv dqvksknnds lsasealclk sdtgklrsds
     2881 hsrshspnhn tlqalkadgr nsglraespn pgsrssspkq kttssgrssp stnssprsss
     2941 phdknlpakv spskahldpp rersksdsyt ldpdtlrkkk vpfmeplrgr stspkpkmsp
     3001 keskggssns enrapsphvv qenlhsevve vcrsstllsn deandenael hnaeegsskv
     3061 hfsigkapvk eelesrsspk vsrktssrhv rpkkdksgpl fkgenvrpte pakqamspsv
     3121 aecaravfaa flwhegivhd amacssflkf npeltkehap irnslscqqg leekesklkn
     3181 rhsleissal nmfnisphgp diskmgsink nkvlsmlkep plpekcedgk seavsyemts
     3241 hssmrsksil pltlqhlvaf wedismatik aatqnmifps pgssailkkk enekdskktk
     3301 kekkkkekae vrprgnlfge maqlamggpe kdticelcge shpypvtyhm rqahpgcgry
     3361 aggqgynsig hfcggwagnc gdggiggstw ylvcdrcrek ylrekqtaar ekvkqsrkkp
     3421 lqvktpralp tmeahqvira nalyllslss aaepsllchh ppkpfhahlp slkegvseel
     3481 pnkmgclylq tlarqhtenf gayqddnlfq demrylrsts vpapyisvtp dacpnvfeep
     3541 gsnmksmpps letspitdsd takrtvfqrs ysvvaseydk qhsssparvk avprrrvhsg
     3601 daevgssllr hpspelsrli sahgslskge rnfqwpvlaf viqhhdlegl evamkhalrk
     3661 sacrvfamea fnwllcnvtq ttslhdilwh fvasltpspf eteeeeeeen kgnkenleqe
     3721 kdlgvcehpl sdiliageaa hplphtfhrl lqtisdlmms lpsgsslqqm alrcwslkfk
     3781 qsdhqflhqs nvfhhinnil sksddgdsee sfnisvqsgy eaisqelcvv tclkdltsvv
     3841 diktssrpam igsltdgste tfwesgdedk nktksitisc vkginasyvs vhvdnsrdig
     3901 nkvtsliflc gkavedicri kqidldsrhm gwvtselpgg dhhvikielk gpentlrvrq
     3961 vkvlgwkege sikiagqisa svtqqkncea etlrvfrlit sqvfgklicg daeptpeqee
     4021 knllsspege dkapsdadlk ehmvgiifsr skltnlqkqv cahivqairm eatrvreewe
     4081 haisskenan sqpsdddass daycfellsm vlalsgsnvg rqylaqqltl lqdlfsllht
     4141 asprvqrqvt sllrrvlpev tpmrlasvig vkalppadis diihsteksd wsklgildmf
     4201 lgciskaltv qlkakgttiv gtagtaagkg vttvtlpmif nssyirrgis hwwmkgstpp
     4261 qiaeiiiklv kdmaaghlsd awsrvtknai aetiialtkm eeehrcpvrc iattrlwlal
     4321 aslcvldqdh vdrlssgrwm gkdgqqkqmp mcdnhddget aaiilcnacg nlctdcdrfl
     4381 hlhrrtrthq rqvfkeeeea ikvdlhegcg rtklfwlmal adsktmkamv efrehtgkpa
     4441 ssssdvcrfc gtrngtelsa vgsvcsdqdc qeyaklacsk thpcghpcgg vkneelclpc
     4501 lhgcdksatc lkqdaddmcm icftealsaa paiqmdcshv fhlqctrrvl enrwlgprit
     4561 fgfmscpick nkinhsvlkd lldpikelye dvrrkalmrl eyeglhksea itmsgarfyn
     4621 npagfamnry ayyvcfkckk ayfggearcd aeagqgddyd prelicgacs dvsraqmcsk
     4681 hgtdfleykc ryccsvavff cfgtthfcna chddfqrmts vpkeelphcp agpkgkqleg
     4741 secplhvvhp ptgeefalgc gvcrnahtf
//
LOCUS       XP_026128315            4768 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X2 [Carassius auratus].
ACCESSION   XP_026128315
VERSION     XP_026128315.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272530.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4768
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4768
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X2"
                     /calculated_mol_wt=522204
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4349..4397
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4515..4569
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4768
                     /gene="LOC113109035"
                     /coded_by="XM_026272530.1:450..14756"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdnifsts qgvrdidfls wttltcfpqe grsnlddygk
     2581 etsghpsqda nvgdlgtgqg ggpglykvvk tgpsghnirs cpnlrgipig mlvlgnkvka
     2641 vgevinpegt wvqldknsvv efcesddgea wslardrggn qylrheeeqv ilehgaqtpp
     2701 pspfsvqafn rgmdssgaqg fdyginnkgd rlsailnsiq sgpflptpsi feqaakppss
     2761 lvhspfvfgq slsqqpqphp qlpnassrsl asrervhksn atgpgttlss lvlrqkgdrd
     2821 nlasrsmspg skhrqesrss ktdshssrsv dqvksknnds lsasealclk sdtgklrsds
     2881 hsrshspnhn tlqalkadgr nsglraespn pgsrssspkq kttssgrssp stnssprsss
     2941 phdknlpakv spskahldpp rersksdsyt ldpdtlrkkk vpfmeplrgr stspkpkmsp
     3001 keskggssns enrapsphvv qenlhsevve vcrsstllsn deandenael hnaeegsskv
     3061 hfsigkapvk eelesrsspk vsrktssrhv rpkkdksgpl fkgenvrpte pakqamspsv
     3121 aecaravfaa flwhegivhd amacssflkf npeltkehap irnslscqqg leekesklkn
     3181 rhsleissal nmfnisphgp diskmgsink nkvlsmlkep plpekcedgk seavsyemts
     3241 hssmrsksil pltlqhlvaf wedismatik aatqnmifps pgssailkkk enekdskktk
     3301 kekkkkekae vrprgnlfge maqlamggpe kdticelcge shpypvtyhm rqahpgcgry
     3361 aggqgynsig hfcggwagnc gdggiggstw ylvcdrcrek ylrekqtaar ekvkqsrkkp
     3421 lqvktpralp tmeahqvira nalyllslss aaepsllchh ppkpfhahlp slkegvseel
     3481 pnkmgclylq tlarqhtenf gayqddnlfq demrylrsts vpapyisvtp dacpnvfeep
     3541 gsnmksmpps letspitdsd takrtvfqrs ysvvaseydk qhsssparvk avprrrvhsg
     3601 davgssllrh pspelsrlis ahgslskger nfqwpvlafv iqhhdlegle vamkhalrks
     3661 acrvfameaf nwllcnvtqt tslhdilwhf vasltpspfe teeeeeeenk gnkenleqek
     3721 dlgvcehpls diliageaah plphtfhrll qtisdlmmsl psgsslqqma lrcwslkfkq
     3781 sdhqflhqsn vfhhinnils ksddgdsees fnisvqsgye aisqelcvvt clkdltsvvd
     3841 iktssrpami gsltdgstet fwesgdedkn ktksitiscv kginasyvsv hvdnsrdign
     3901 kvtsliflcg kavedicrik qidldsrhmg wvtselpggd hhvikielkg pentlrvrqv
     3961 kvlgwkeges ikiagqisas vtqqknceae tlrvfrlits qvfgklicgd aeptpeqeek
     4021 nllsspeged kapsdadlke hmvgiifsrs kltnlqkqvc ahivqairme atrvreeweh
     4081 aisskenans qpsdddassd aycfellsmv lalsgsnvgr qylaqqltll qdlfsllhta
     4141 sprvqrqvts llrrvlpevt pmrlasvigv kalppadisd iihsteksdw sklgildmfl
     4201 gciskaltvq lkakgttivg tagtaagkgv ttvtlpmifn ssyirrgish wwmkgstppq
     4261 iaeiiiklvk dmaaghlsda wsrvtknaia etiialtkme eehrcpvrci attrlwlala
     4321 slcvldqdhv drlssgrwmg kdgqqkqmpm cdnhddgeta aiilcnacgn lctdcdrflh
     4381 lhrrtrthqr qvfkeeeeai kvdlhegcgr tklfwlmala dsktmkamve frehtgkpas
     4441 sssdvcrfcg trngtelsav gsvcsdqdcq eyaklacskt hpcghpcggv kneelclpcl
     4501 hgcdksatcl kqdaddmcmi cftealsaap aiqmdcshvf hlqctrrvle nrwlgpritf
     4561 gfmscpickn kinhsvlkdl ldpikelyed vrrkalmrle yeglhkseai tmsgarfynn
     4621 pagfamnrya yyvcfkckka yfggearcda eagqgddydp relicgacsd vsraqmcskh
     4681 gtdfleykcr yccsvavffc fgtthfcnac hddfqrmtsv pkeelphcpa gpkgkqlegs
     4741 ecplhvvhpp tgeefalgcg vcrnahtf
//
LOCUS       XP_026128316            4761 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X3 [Carassius auratus].
ACCESSION   XP_026128316
VERSION     XP_026128316.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272531.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4761
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4761
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X3"
                     /calculated_mol_wt=521578
     Region          574..1010
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1220..1370
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1711..1870
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2377..2428
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2460..2522
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4342..4390
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4508..4562
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4761
                     /gene="LOC113109035"
                     /coded_by="XM_026272531.1:449..14734"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllgvnieeh
      841 tqirqeekrq rinrrhrlee grgplvfpgp llmnqreqvl arlrplqafk lmreklkdgs
      901 sergdkdask ittyppgavr fdcelravqv scgfhhsvvl mengdvytfg ygqhgqlghg
      961 dvnsrgspsl vqalpgpstq vtagsnhtav lltdgqvftf gsfskgqlgr pildmpywna
     1021 kpspmpniga kygrkatwig asgdqtffri dealinshil atseifaskh iiglvptsvs
     1081 epppfkclli nkldgscrtf ndseqedlqg fglcldpvyd viwrflpatr emccynavia
     1141 darvptasdi qalcsilspe lalpsgshas ttrshgalhi lgcldtlaam qelkmcvasa
     1201 eeetqavmkv yskedysvvn rfeshgggwg ysahsveair fcadadillg glglfggrge
     1261 ytakiklfel gpdggdhetd gdllaetdvl aydcaareky ammfdepvll qlgwwyvawa
     1321 rvsgpssdcg shgqatittd dgvvfqfkss kksnngtdvn agqipqllyr lpsndgnask
     1381 gkqqtsepvh ilkrsfartv svdcfeslls vlhwswttlv lgveelrglk gfqftatlld
     1441 lerlrfvgtc clrllrvyic eifpisastk avveesskla ecvgktrsll kkilsegmdn
     1501 cltkldndpq gylsqpltll eavlqechnt ftacfhsfyp tpalqwaclc dllncldqdi
     1561 qeanfrtsss rllaavmsal cntsvkltsv lpiaydgevl lrslvkqvsi endsalahrf
     1621 pllvahmekl shteenlmgm ttfrevlekm lvivvlpvrk slrkevelfs phlvsntcgl
     1681 lasivselta salgsevdgl nslhsvkstp nrftktsqgr swntgngspd aicftvdkpg
     1741 vvlvgfcvyg gggiheyele vladdaqteh pgdsahshrw tslelvkgty stddspsdia
     1801 eirldkavpl kenvkyavrl rnygsrtang dggittvqcs dgvsftfstc slssngtnqt
     1861 rgqvpqilyy rseydgdlqs qllskaneed kncsralsvv svvvraakdl lhrafavdve
     1921 dipellssss lfsmllplil ayigpvaasv pkaavevfgl vqellpavsa lnqkyappaf
     1981 npnqstdstt gnqpeqglsa cttsnhyavi esdhpykqaa vtqykvsfpd cvrwvtiefd
     2041 pqcgtaqped vlrllipsrs mhfsglgsks lahetinswt elkkfsgstg wptsvlvlpg
     2101 neahfsleta sdyvkdekac fygfkcvavg yefnpgldeg iiqlekelsy lgsvcaaalm
     2161 kkdlalpign eleedleile easlqvckah sgllgkglal thsptileal egnlplhlqt
     2221 nehsfledfi tcvqnssggr larwlqpdsy adpqktslil nkddircgwp ttvvvqtkdq
     2281 ygdvvhvpnm kvevkavpvs qkksiqqenm kklqrlpgss snstsgtdlt ygghpppkle
     2341 atyepmiike aryiaitmmk ayenysfeel rfasptpkrp senmlirant dgtysanwtp
     2401 gavglytihv tidgieidag levevkdppk gmippgtqmv kpkaepqpck vrkfvakdsa
     2461 glrvrshpsl qseqigivqv ngtitfidei hnddgvwlrl ndetvkkyvp nmngyieawc
     2521 lsfnqhlgrs llvpvdnifs tsqgvrdidf lswttltcfp qegrsnlddy gketsghpsq
     2581 danvgdlgtg qgggpglykv vktgpsghni rscpnlrgip igmlvlgnkv kavgevinpe
     2641 gtwvqldkns vvefcesddg eawslardrg gnqylrheee qvilehgaqt pppspfsvqa
     2701 fnrgmdssga qgfdyginnk gdrlsailns iqsgpflptp sifeqaakpp sslvhspfvf
     2761 gqslsqqpqp hpqlpnassr slasrervhk snatgpgttl sslvlrqkgd rdnlasrsms
     2821 pgskhrqesr ssktdshssr svdqvksknn dslsasealc lksdtgklrs dshsrshspn
     2881 hntlqalkad grnsglraes pnpgsrsssp kqkttssgrs spstnssprs ssphdknlpa
     2941 kvspskahld pprersksds ytldpdtlrk kkvpfmeplr grstspkpkm spkeskggss
     3001 nsenrapsph vvqenlhsev vevcrsstll sndeandena elhnaeegss kvhfsigkap
     3061 vkeelesrss pkvsrktssr hvrpkkdksg plfkgenvrp tepakqamsp svaecaravf
     3121 aaflwhegiv hdamacssfl kfnpeltkeh apirnslscq qgleekeskl knrhsleiss
     3181 alnmfnisph gpdiskmgsi nknkvlsmlk epplpekced gkseavsyem tshssmrsks
     3241 ilpltlqhlv afwedismat ikaatqnmif pspgssailk kkenekdskk tkkekkkkek
     3301 aevrprgnlf gemaqlamgg pekdticelc geshpypvty hmrqahpgcg ryaggqgyns
     3361 ighfcggwag ncgdggiggs twylvcdrcr ekylrekqta arekvkqsrk kplqvktpra
     3421 lptmeahqvi ranalyllsl ssaaepsllc hhppkpfhah lpslkegvse elpnkmgcly
     3481 lqtlarqhte nfgayqddnl fqdemrylrs tsvpapyisv tpdacpnvfe epgsnmksmp
     3541 psletspitd sdtakrtvfq rsysvvasey dkqhssspar vkavprrrvh sgdaevgssl
     3601 lrhpspelsr lisahgslsk gernfqwpvl afviqhhdle glevamkhal rksacrvfam
     3661 eafnwllcnv tqttslhdil whfvasltps pfeteeeeee enkgnkenle qekdlgvceh
     3721 plsdiliage aahplphtfh rllqtisdlm mslpsgsslq qmalrcwslk fkqsdhqflh
     3781 qsnvfhhinn ilsksddgds eesfnisvqs gyeaisqelc vvtclkdlts vvdiktssrp
     3841 amigsltdgs tetfwesgde dknktksiti scvkginasy vsvhvdnsrd ignkvtslif
     3901 lcgkavedic rikqidldsr hmgwvtselp ggdhhvikie lkgpentlrv rqvkvlgwke
     3961 gesikiagqi sasvtqqknc eaetlrvfrl itsqvfgkli cgdaeptpeq eeknllsspe
     4021 gedkapsdad lkehmvgiif srskltnlqk qvcahivqai rmeatrvree wehaissken
     4081 ansqpsddda ssdaycfell smvlalsgsn vgrqylaqql tllqdlfsll htasprvqrq
     4141 vtsllrrvlp evtpmrlasv igvkalppad isdiihstek sdwsklgild mflgciskal
     4201 tvqlkakgtt ivgtagtaag kgvttvtlpm ifnssyirrg ishwwmkgst ppqiaeiiik
     4261 lvkdmaaghl sdawsrvtkn aiaetiialt kmeeehrcpv rciattrlwl alaslcvldq
     4321 dhvdrlssgr wmgkdgqqkq mpmcdnhddg etaaiilcna cgnlctdcdr flhlhrrtrt
     4381 hqrqvfkeee eaikvdlheg cgrtklfwlm aladsktmka mvefrehtgk passssdvcr
     4441 fcgtrngtel savgsvcsdq dcqeyaklac skthpcghpc ggvkneelcl pclhgcdksa
     4501 tclkqdaddm cmicfteals aapaiqmdcs hvfhlqctrr vlenrwlgpr itfgfmscpi
     4561 cknkinhsvl kdlldpikel yedvrrkalm rleyeglhks eaitmsgarf ynnpagfamn
     4621 ryayyvcfkc kkayfggear cdaeagqgdd ydprelicga csdvsraqmc skhgtdfley
     4681 kcryccsvav ffcfgtthfc nachddfqrm tsvpkeelph cpagpkgkql egsecplhvv
     4741 hpptgeefal gcgvcrnaht f
//
LOCUS       XP_026128317            4744 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X4 [Carassius auratus].
ACCESSION   XP_026128317
VERSION     XP_026128317.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272532.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4744
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4744
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X4"
                     /calculated_mol_wt=519474
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4325..4373
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4491..4545
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4744
                     /gene="LOC113109035"
                     /coded_by="XM_026272532.1:448..14682"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdegrsnl ddygketsgh psqdanvgdl gtgqgggpgl
     2581 ykvvktgpsg hnirscpnlr gipigmlvlg nkvkavgevi npegtwvqld knsvvefces
     2641 ddgeawslar drggnqylrh eeeqvilehg aqtpppspfs vqafnrgmds sgaqgfdygi
     2701 nnkgdrlsai lnsiqsgpfl ptpsifeqaa kppsslvhsp fvfgqslsqq pqphpqlpna
     2761 ssrslasrer vhksnatgpg ttlsslvlrq kgdrdnlasr smspgskhrq esrssktdsh
     2821 ssrsvdqvks knndslsase alclksdtgk lrsdshsrsh spnhntlqal kadgrnsglr
     2881 aespnpgsrs sspkqkttss grsspstnss prsssphdkn lpakvspska hldpprersk
     2941 sdsytldpdt lrkkkvpfme plrgrstspk pkmspkeskg gssnsenrap sphvvqenlh
     3001 sevvevcrss tllsndeand enaelhnaee gsskvhfsig kapvkeeles rsspkvsrkt
     3061 ssrhvrpkkd ksgplfkgen vrptepakqa mspsvaecar avfaaflwhe givhdamacs
     3121 sflkfnpelt kehapirnsl scqqgleeke sklknrhsle issalnmfni sphgpdiskm
     3181 gsinknkvls mlkepplpek cedgkseavs yemtshssmr sksilpltlq hlvafwedis
     3241 matikaatqn mifpspgssa ilkkkenekd skktkkekkk kekaevrprg nlfgemaqla
     3301 mggpekdtic elcgeshpyp vtyhmrqahp gcgryaggqg ynsighfcgg wagncgdggi
     3361 ggstwylvcd rcrekylrek qtaarekvkq srkkplqvkt pralptmeah qviranalyl
     3421 lslssaaeps llchhppkpf hahlpslkeg vseelpnkmg clylqtlarq htenfgayqd
     3481 dnlfqdemry lrstsvpapy isvtpdacpn vfeepgsnmk smppsletsp itdsdtakrt
     3541 vfqrsysvva seydkqhsss parvkavprr rvhsgdaevg ssllrhpspe lsrlisahgs
     3601 lskgernfqw pvlafviqhh dleglevamk halrksacrv fameafnwll cnvtqttslh
     3661 dilwhfvasl tpspfeteee eeeenkgnke nleqekdlgv cehplsdili ageaahplph
     3721 tfhrllqtis dlmmslpsgs slqqmalrcw slkfkqsdhq flhqsnvfhh innilsksdd
     3781 gdseesfnis vqsgyeaisq elcvvtclkd ltsvvdikts srpamigslt dgstetfwes
     3841 gdedknktks itiscvkgin asyvsvhvdn srdignkvts liflcgkave dicrikqidl
     3901 dsrhmgwvts elpggdhhvi kielkgpent lrvrqvkvlg wkegesikia gqisasvtqq
     3961 knceaetlrv frlitsqvfg klicgdaept peqeeknlls spegedkaps dadlkehmvg
     4021 iifsrskltn lqkqvcahiv qairmeatrv reewehaiss kenansqpsd ddassdaycf
     4081 ellsmvlals gsnvgrqyla qqltllqdlf sllhtasprv qrqvtsllrr vlpevtpmrl
     4141 asvigvkalp padisdiihs teksdwsklg ildmflgcis kaltvqlkak gttivgtagt
     4201 aagkgvttvt lpmifnssyi rrgishwwmk gstppqiaei iiklvkdmaa ghlsdawsrv
     4261 tknaiaetii altkmeeehr cpvrciattr lwlalaslcv ldqdhvdrls sgrwmgkdgq
     4321 qkqmpmcdnh ddgetaaiil cnacgnlctd cdrflhlhrr trthqrqvfk eeeeaikvdl
     4381 hegcgrtklf wlmaladskt mkamvefreh tgkpassssd vcrfcgtrng telsavgsvc
     4441 sdqdcqeyak lacskthpcg hpcggvknee lclpclhgcd ksatclkqda ddmcmicfte
     4501 alsaapaiqm dcshvfhlqc trrvlenrwl gpritfgfms cpicknkinh svlkdlldpi
     4561 kelyedvrrk almrleyegl hkseaitmsg arfynnpagf amnryayyvc fkckkayfgg
     4621 earcdaeagq gddydpreli cgacsdvsra qmcskhgtdf leykcryccs vavffcfgtt
     4681 hfcnachddf qrmtsvpkee lphcpagpkg kqlegsecpl hvvhpptgee falgcgvcrn
     4741 ahtf
//
LOCUS       XP_026128318            4736 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X5 [Carassius auratus].
ACCESSION   XP_026128318
VERSION     XP_026128318.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272533.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4736
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4736
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X5"
                     /calculated_mol_wt=518871
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4317..4365
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4483..4537
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4736
                     /gene="LOC113109035"
                     /coded_by="XM_026272533.1:1..14211"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdnifsts qgvrdidfls wttltcfpqe grsnlddygk
     2581 etsghpsqda nvgdlgtgqg ggpglykvvk tgpsghnirs cpnlrgipig mlvlgnkvka
     2641 vgevinpegt wvqldknsvv efcesddgea wslardrggn qylrheeeqv ilehgaqtpp
     2701 pspfsvqafn rgmdssgaqg fdyginnkgd rlsailnsiq sgpflptpsi feqaakppss
     2761 lvhspfvfgq slsqqpqphp qlpsdrdnla srsmspgskh rqesrssktd shssrsvdqv
     2821 ksknndslsa sealclksdt gklrsdshsr shspnhntlq alkadgrnsg lraespnpgs
     2881 rssspkqktt ssgrsspstn ssprsssphd knlpakvsps kahldpprer sksdsytldp
     2941 dtlrkkkvpf meplrgrsts pkpkmspkes kggssnsenr apsphvvqen lhsevvevcr
     3001 sstllsndea ndenaelhna eegsskvhfs igkapvkeel esrsspkvsr ktssrhvrpk
     3061 kdksgplfkg envrptepak qamspsvaec aravfaaflw hegivhdama cssflkfnpe
     3121 ltkehapirn slscqqglee kesklknrhs leissalnmf nisphgpdis kmgsinknkv
     3181 lsmlkepplp ekcedgksea vsyemtshss mrsksilplt lqhlvafwed ismatikaat
     3241 qnmifpspgs sailkkkene kdskktkkek kkkekaevrp rgnlfgemaq lamggpekdt
     3301 icelcgeshp ypvtyhmrqa hpgcgryagg qgynsighfc ggwagncgdg giggstwylv
     3361 cdrcrekylr ekqtaarekv kqsrkkplqv ktpralptme ahqviranal yllslssaae
     3421 psllchhppk pfhahlpslk egvseelpnk mgclylqtla rqhtenfgay qddnlfqdem
     3481 rylrstsvpa pyisvtpdac pnvfeepgsn mksmppslet spitdsdtak rtvfqrsysv
     3541 vaseydkqhs ssparvkavp rrrvhsgdae vgssllrhps pelsrlisah gslskgernf
     3601 qwpvlafviq hhdlegleva mkhalrksac rvfameafnw llcnvtqtts lhdilwhfva
     3661 sltpspfete eeeeeenkgn kenleqekdl gvcehplsdi liageaahpl phtfhrllqt
     3721 isdlmmslps gsslqqmalr cwslkfkqsd hqflhqsnvf hhinnilsks ddgdseesfn
     3781 isvqsgyeai sqelcvvtcl kdltsvvdik tssrpamigs ltdgstetfw esgdedknkt
     3841 ksitiscvkg inasyvsvhv dnsrdignkv tsliflcgka vedicrikqi dldsrhmgwv
     3901 tselpggdhh vikielkgpe ntlrvrqvkv lgwkegesik iagqisasvt qqknceaetl
     3961 rvfrlitsqv fgklicgdae ptpeqeeknl lsspegedka psdadlkehm vgiifsrskl
     4021 tnlqkqvcah ivqairmeat rvreewehai sskenansqp sdddassday cfellsmvla
     4081 lsgsnvgrqy laqqltllqd lfsllhtasp rvqrqvtsll rrvlpevtpm rlasvigvka
     4141 lppadisdii hsteksdwsk lgildmflgc iskaltvqlk akgttivgta gtaagkgvtt
     4201 vtlpmifnss yirrgishww mkgstppqia eiiiklvkdm aaghlsdaws rvtknaiaet
     4261 iialtkmeee hrcpvrciat trlwlalasl cvldqdhvdr lssgrwmgkd gqqkqmpmcd
     4321 nhddgetaai ilcnacgnlc tdcdrflhlh rrtrthqrqv fkeeeeaikv dlhegcgrtk
     4381 lfwlmalads ktmkamvefr ehtgkpasss sdvcrfcgtr ngtelsavgs vcsdqdcqey
     4441 aklacskthp cghpcggvkn eelclpclhg cdksatclkq daddmcmicf tealsaapai
     4501 qmdcshvfhl qctrrvlenr wlgpritfgf mscpicknki nhsvlkdlld pikelyedvr
     4561 rkalmrleye glhkseaitm sgarfynnpa gfamnryayy vcfkckkayf ggearcdaea
     4621 gqgddydpre licgacsdvs raqmcskhgt dfleykcryc csvavffcfg tthfcnachd
     4681 dfqrmtsvpk eelphcpagp kgkqlegsec plhvvhpptg eefalgcgvc rnahtf
//
LOCUS       XP_026128319            4735 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X6 [Carassius auratus].
ACCESSION   XP_026128319
VERSION     XP_026128319.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272534.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4735
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4735
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X6"
                     /calculated_mol_wt=518742
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4316..4364
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4482..4536
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4735
                     /gene="LOC113109035"
                     /coded_by="XM_026272534.1:449..14656"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdnifsts qgvrdidfls wttltcfpqe grsnlddygk
     2581 etsghpsqda nvgdlgtgqg ggpglykvvk tgpsghnirs cpnlrgipig mlvlgnkvka
     2641 vgevinpegt wvqldknsvv efcesddgea wslardrggn qylrheeeqv ilehgaqtpp
     2701 pspfsvqafn rgmdssgaqg fdyginnkgd rlsailnsiq sgpflptpsi feqaakppss
     2761 lvhspfvfgq slsqqpqphp qlpsdrdnla srsmspgskh rqesrssktd shssrsvdqv
     2821 ksknndslsa sealclksdt gklrsdshsr shspnhntlq alkadgrnsg lraespnpgs
     2881 rssspkqktt ssgrsspstn ssprsssphd knlpakvsps kahldpprer sksdsytldp
     2941 dtlrkkkvpf meplrgrsts pkpkmspkes kggssnsenr apsphvvqen lhsevvevcr
     3001 sstllsndea ndenaelhna eegsskvhfs igkapvkeel esrsspkvsr ktssrhvrpk
     3061 kdksgplfkg envrptepak qamspsvaec aravfaaflw hegivhdama cssflkfnpe
     3121 ltkehapirn slscqqglee kesklknrhs leissalnmf nisphgpdis kmgsinknkv
     3181 lsmlkepplp ekcedgksea vsyemtshss mrsksilplt lqhlvafwed ismatikaat
     3241 qnmifpspgs sailkkkene kdskktkkek kkkekaevrp rgnlfgemaq lamggpekdt
     3301 icelcgeshp ypvtyhmrqa hpgcgryagg qgynsighfc ggwagncgdg giggstwylv
     3361 cdrcrekylr ekqtaarekv kqsrkkplqv ktpralptme ahqviranal yllslssaae
     3421 psllchhppk pfhahlpslk egvseelpnk mgclylqtla rqhtenfgay qddnlfqdem
     3481 rylrstsvpa pyisvtpdac pnvfeepgsn mksmppslet spitdsdtak rtvfqrsysv
     3541 vaseydkqhs ssparvkavp rrrvhsgdav gssllrhpsp elsrlisahg slskgernfq
     3601 wpvlafviqh hdleglevam khalrksacr vfameafnwl lcnvtqttsl hdilwhfvas
     3661 ltpspfetee eeeeenkgnk enleqekdlg vcehplsdil iageaahplp htfhrllqti
     3721 sdlmmslpsg sslqqmalrc wslkfkqsdh qflhqsnvfh hinnilsksd dgdseesfni
     3781 svqsgyeais qelcvvtclk dltsvvdikt ssrpamigsl tdgstetfwe sgdedknktk
     3841 sitiscvkgi nasyvsvhvd nsrdignkvt sliflcgkav edicrikqid ldsrhmgwvt
     3901 selpggdhhv ikielkgpen tlrvrqvkvl gwkegesiki agqisasvtq qknceaetlr
     3961 vfrlitsqvf gklicgdaep tpeqeeknll sspegedkap sdadlkehmv giifsrsklt
     4021 nlqkqvcahi vqairmeatr vreewehais skenansqps dddassdayc fellsmvlal
     4081 sgsnvgrqyl aqqltllqdl fsllhtaspr vqrqvtsllr rvlpevtpmr lasvigvkal
     4141 ppadisdiih steksdwskl gildmflgci skaltvqlka kgttivgtag taagkgvttv
     4201 tlpmifnssy irrgishwwm kgstppqiae iiiklvkdma aghlsdawsr vtknaiaeti
     4261 ialtkmeeeh rcpvrciatt rlwlalaslc vldqdhvdrl ssgrwmgkdg qqkqmpmcdn
     4321 hddgetaaii lcnacgnlct dcdrflhlhr rtrthqrqvf keeeeaikvd lhegcgrtkl
     4381 fwlmaladsk tmkamvefre htgkpassss dvcrfcgtrn gtelsavgsv csdqdcqeya
     4441 klacskthpc ghpcggvkne elclpclhgc dksatclkqd addmcmicft ealsaapaiq
     4501 mdcshvfhlq ctrrvlenrw lgpritfgfm scpicknkin hsvlkdlldp ikelyedvrr
     4561 kalmrleyeg lhkseaitms garfynnpag famnryayyv cfkckkayfg gearcdaeag
     4621 qgddydprel icgacsdvsr aqmcskhgtd fleykcrycc svavffcfgt thfcnachdd
     4681 fqrmtsvpke elphcpagpk gkqlegsecp lhvvhpptge efalgcgvcr nahtf
//
LOCUS       XP_026128320            4734 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X7 [Carassius auratus].
ACCESSION   XP_026128320
VERSION     XP_026128320.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272535.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4734
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4734
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X7"
                     /calculated_mol_wt=518262
     Region          574..983
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1193..1343
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1684..1843
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2350..2401
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2433..2495
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4315..4363
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4481..4535
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4734
                     /gene="LOC113109035"
                     /coded_by="XM_026272535.1:449..14653"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr dgssergdkd askittyppg avrfdcelra
      901 vqvscgfhhs vvlmengdvy tfgygqhgql ghgdvnsrgs pslvqalpgp stqvtagsnh
      961 tavlltdgqv ftfgsfskgq lgrpildmpy wnakpspmpn igakygrkat wigasgdqtf
     1021 fridealins hilatseifa skhiiglvpt svsepppfkc llinkldgsc rtfndseqed
     1081 lqgfglcldp vydviwrflp atremccyna viadarvpta sdiqalcsil spelalpsgs
     1141 hasttrshga lhilgcldtl aamqelkmcv asaeeetqav mkvyskedys vvnrfeshgg
     1201 gwgysahsve airfcadadi llgglglfgg rgeytakikl felgpdggdh etdgdllaet
     1261 dvlaydcaar ekyammfdep vllqlgwwyv awarvsgpss dcgshgqati ttddgvvfqf
     1321 ksskksnngt dvnagqipql lyrlpsndgn askgkqqtse pvhilkrsfa rtvsvdcfes
     1381 llsvlhwswt tlvlgveelr glkgfqftat lldlerlrfv gtcclrllrv yiceifpisa
     1441 stkavveess klaecvgktr sllkkilseg mdncltkldn dpqgylsqpl tlleavlqec
     1501 hntftacfhs fyptpalqwa clcdllncld qdiqeanfrt sssrllaavm salcntsvkl
     1561 tsvlpiaydg evllrslvkq vsiendsala hrfpllvahm eklshteenl mgmttfrevl
     1621 ekmlvivvlp vrkslrkeve lfsphlvsnt cgllasivse ltasalgsev dglnslhsvk
     1681 stpnrftkts qgrswntgng spdaicftvd kpgvvlvgfc vyggggihey elevladdaq
     1741 tehpgdsahs hrwtslelvk gtystddsps diaeirldka vplkenvkya vrlrnygsrt
     1801 angdggittv qcsdgvsftf stcslssngt nqtrgqvpqi lyyrseydgd lqsqllskan
     1861 eedkncsral svvsvvvraa kdllhrafav dvedipells ssslfsmllp lilayigpva
     1921 asvpkaavev fglvqellpa vsalnqkyap pafnpnqstd sttgnqpeqg lsacttsnhy
     1981 aviesdhpyk qaavtqykvs fpdcvrwvti efdpqcgtaq pedvlrllip srsmhfsglg
     2041 skslahetin swtelkkfsg stgwptsvlv lpgneahfsl etasdyvkde kacfygfkcv
     2101 avgyefnpgl degiiqleke lsylgsvcaa almkkdlalp igneleedle ileeaslqvc
     2161 kahsgllgkg lalthsptil ealegnlplh lqtnehsfle dfitcvqnss ggrlarwlqp
     2221 dsyadpqkts lilnkddirc gwpttvvvqt kdqygdvvhv pnmkvevkav pvsqkksiqq
     2281 enmkklqrlp gsssnstsgt dltygghppp kleatyepmi ikearyiait mmkayenysf
     2341 eelrfasptp krpsenmlir antdgtysan wtpgavglyt ihvtidgiei daglevevkd
     2401 ppkgmippgt qmvkpkaepq pckvrkfvak dsaglrvrsh pslqseqigi vqvngtitfi
     2461 deihnddgvw lrlndetvkk yvpnmngyie awclsfnqhl grsllvpvdn ifstsqgvrd
     2521 idflswttlt cfpqegrsnl ddygketsgh psqdanvgdl gtgqgggpgl ykvvktgpsg
     2581 hnirscpnlr gipigmlvlg nkvkavgevi npegtwvqld knsvvefces ddgeawslar
     2641 drggnqylrh eeeqvilehg aqtpppspfs vqafnrgmds sgaqgfdygi nnkgdrlsai
     2701 lnsiqsgpfl ptpsifeqaa kppsslvhsp fvfgqslsqq pqphpqlpna ssrslasrer
     2761 vhksnatgpg ttlsslvlrq kgdrdnlasr smspgskhrq esrssktdsh ssrsvdqvks
     2821 knndslsase alclksdtgk lrsdshsrsh spnhntlqal kadgrnsglr aespnpgsrs
     2881 sspkqkttss grsspstnss prsssphdkn lpakvspska hldpprersk sdsytldpdt
     2941 lrkkkvpfme plrgrstspk pkmspkeskg gssnsenrap sphvvqenlh sevvevcrss
     3001 tllsndeand enaelhnaee gsskvhfsig kapvkeeles rsspkvsrkt ssrhvrpkkd
     3061 ksgplfkgen vrptepakqa mspsvaecar avfaaflwhe givhdamacs sflkfnpelt
     3121 kehapirnsl scqqgleeke sklknrhsle issalnmfni sphgpdiskm gsinknkvls
     3181 mlkepplpek cedgkseavs yemtshssmr sksilpltlq hlvafwedis matikaatqn
     3241 mifpspgssa ilkkkenekd skktkkekkk kekaevrprg nlfgemaqla mggpekdtic
     3301 elcgeshpyp vtyhmrqahp gcgryaggqg ynsighfcgg wagncgdggi ggstwylvcd
     3361 rcrekylrek qtaarekvkq srkkplqvkt pralptmeah qviranalyl lslssaaeps
     3421 llchhppkpf hahlpslkeg vseelpnkmg clylqtlarq htenfgayqd dnlfqdemry
     3481 lrstsvpapy isvtpdacpn vfeepgsnmk smppsletsp itdsdtakrt vfqrsysvva
     3541 seydkqhsss parvkavprr rvhsgdaevg ssllrhpspe lsrlisahgs lskgernfqw
     3601 pvlafviqhh dleglevamk halrksacrv fameafnwll cnvtqttslh dilwhfvasl
     3661 tpspfeteee eeeenkgnke nleqekdlgv cehplsdili ageaahplph tfhrllqtis
     3721 dlmmslpsgs slqqmalrcw slkfkqsdhq flhqsnvfhh innilsksdd gdseesfnis
     3781 vqsgyeaisq elcvvtclkd ltsvvdikts srpamigslt dgstetfwes gdedknktks
     3841 itiscvkgin asyvsvhvdn srdignkvts liflcgkave dicrikqidl dsrhmgwvts
     3901 elpggdhhvi kielkgpent lrvrqvkvlg wkegesikia gqisasvtqq knceaetlrv
     3961 frlitsqvfg klicgdaept peqeeknlls spegedkaps dadlkehmvg iifsrskltn
     4021 lqkqvcahiv qairmeatrv reewehaiss kenansqpsd ddassdaycf ellsmvlals
     4081 gsnvgrqyla qqltllqdlf sllhtasprv qrqvtsllrr vlpevtpmrl asvigvkalp
     4141 padisdiihs teksdwsklg ildmflgcis kaltvqlkak gttivgtagt aagkgvttvt
     4201 lpmifnssyi rrgishwwmk gstppqiaei iiklvkdmaa ghlsdawsrv tknaiaetii
     4261 altkmeeehr cpvrciattr lwlalaslcv ldqdhvdrls sgrwmgkdgq qkqmpmcdnh
     4321 ddgetaaiil cnacgnlctd cdrflhlhrr trthqrqvfk eeeeaikvdl hegcgrtklf
     4381 wlmaladskt mkamvefreh tgkpassssd vcrfcgtrng telsavgsvc sdqdcqeyak
     4441 lacskthpcg hpcggvknee lclpclhgcd ksatclkqda ddmcmicfte alsaapaiqm
     4501 dcshvfhlqc trrvlenrwl gpritfgfms cpicknkinh svlkdlldpi kelyedvrrk
     4561 almrleyegl hkseaitmsg arfynnpagf amnryayyvc fkckkayfgg earcdaeagq
     4621 gddydpreli cgacsdvsra qmcskhgtdf leykcryccs vavffcfgtt hfcnachddf
     4681 qrmtsvpkee lphcpagpkg kqlegsecpl hvvhpptgee falgcgvcrn ahtf
//
LOCUS       XP_026128321            4733 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X8 [Carassius auratus].
ACCESSION   XP_026128321
VERSION     XP_026128321.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272536.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4733
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4733
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X8"
                     /calculated_mol_wt=518639
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4314..4362
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4480..4534
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4733
                     /gene="LOC113109035"
                     /coded_by="XM_026272536.1:449..14650"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdnifsts qgvrdidfls wttltcfpqe grsnlddygk
     2581 etsghpsqda nvgdlgtgqg ggpglykvin pegtwvqldk nsvvefcesd dgeawslard
     2641 rggnqylrhe eeqvilehga qtpppspfsv qafnrgmdss gaqgfdygin nkgdrlsail
     2701 nsiqsgpflp tpsifeqaak ppsslvhspf vfgqslsqqp qphpqlpnas srslasrerv
     2761 hksnatgpgt tlsslvlrqk gdrdnlasrs mspgskhrqe srssktdshs srsvdqvksk
     2821 nndslsasea lclksdtgkl rsdshsrshs pnhntlqalk adgrnsglra espnpgsrss
     2881 spkqkttssg rsspstnssp rsssphdknl pakvspskah ldpprersks dsytldpdtl
     2941 rkkkvpfmep lrgrstspkp kmspkeskgg ssnsenraps phvvqenlhs evvevcrsst
     3001 llsndeande naelhnaeeg sskvhfsigk apvkeelesr sspkvsrkts srhvrpkkdk
     3061 sgplfkgenv rptepakqam spsvaecara vfaaflwheg ivhdamacss flkfnpeltk
     3121 ehapirnsls cqqgleekes klknrhslei ssalnmfnis phgpdiskmg sinknkvlsm
     3181 lkepplpekc edgkseavsy emtshssmrs ksilpltlqh lvafwedism atikaatqnm
     3241 ifpspgssai lkkkenekds kktkkekkkk ekaevrprgn lfgemaqlam ggpekdtice
     3301 lcgeshpypv tyhmrqahpg cgryaggqgy nsighfcggw agncgdggig gstwylvcdr
     3361 crekylrekq taarekvkqs rkkplqvktp ralptmeahq viranalyll slssaaepsl
     3421 lchhppkpfh ahlpslkegv seelpnkmgc lylqtlarqh tenfgayqdd nlfqdemryl
     3481 rstsvpapyi svtpdacpnv feepgsnmks mppsletspi tdsdtakrtv fqrsysvvas
     3541 eydkqhsssp arvkavprrr vhsgdaevgs sllrhpspel srlisahgsl skgernfqwp
     3601 vlafviqhhd leglevamkh alrksacrvf ameafnwllc nvtqttslhd ilwhfvaslt
     3661 pspfeteeee eeenkgnken leqekdlgvc ehplsdilia geaahplpht fhrllqtisd
     3721 lmmslpsgss lqqmalrcws lkfkqsdhqf lhqsnvfhhi nnilsksddg dseesfnisv
     3781 qsgyeaisqe lcvvtclkdl tsvvdiktss rpamigsltd gstetfwesg dedknktksi
     3841 tiscvkgina syvsvhvdns rdignkvtsl iflcgkaved icrikqidld srhmgwvtse
     3901 lpggdhhvik ielkgpentl rvrqvkvlgw kegesikiag qisasvtqqk nceaetlrvf
     3961 rlitsqvfgk licgdaeptp eqeeknllss pegedkapsd adlkehmvgi ifsrskltnl
     4021 qkqvcahivq airmeatrvr eewehaissk enansqpsdd dassdaycfe llsmvlalsg
     4081 snvgrqylaq qltllqdlfs llhtasprvq rqvtsllrrv lpevtpmrla svigvkalpp
     4141 adisdiihst eksdwsklgi ldmflgcisk altvqlkakg ttivgtagta agkgvttvtl
     4201 pmifnssyir rgishwwmkg stppqiaeii iklvkdmaag hlsdawsrvt knaiaetiia
     4261 ltkmeeehrc pvrciattrl wlalaslcvl dqdhvdrlss grwmgkdgqq kqmpmcdnhd
     4321 dgetaaiilc nacgnlctdc drflhlhrrt rthqrqvfke eeeaikvdlh egcgrtklfw
     4381 lmaladsktm kamvefreht gkpassssdv crfcgtrngt elsavgsvcs dqdcqeyakl
     4441 acskthpcgh pcggvkneel clpclhgcdk satclkqdad dmcmicftea lsaapaiqmd
     4501 cshvfhlqct rrvlenrwlg pritfgfmsc picknkinhs vlkdlldpik elyedvrrka
     4561 lmrleyeglh kseaitmsga rfynnpagfa mnryayyvcf kckkayfgge arcdaeagqg
     4621 ddydprelic gacsdvsraq mcskhgtdfl eykcryccsv avffcfgtth fcnachddfq
     4681 rmtsvpkeel phcpagpkgk qlegsecplh vvhpptgeef algcgvcrna htf
//
LOCUS       XP_026128322            4726 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X9 [Carassius auratus].
ACCESSION   XP_026128322
VERSION     XP_026128322.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272537.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4726
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4726
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X9"
                     /calculated_mol_wt=517507
     Region          574..975
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1185..1335
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1676..1835
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2342..2393
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2425..2487
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4307..4355
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4473..4527
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4726
                     /gene="LOC113109035"
                     /coded_by="XM_026272537.1:449..14629"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllgvnieeh
      841 tqirqeekrq rinrrhrlee grdgssergd kdaskittyp pgavrfdcel ravqvscgfh
      901 hsvvlmengd vytfgygqhg qlghgdvnsr gspslvqalp gpstqvtags nhtavlltdg
      961 qvftfgsfsk gqlgrpildm pywnakpspm pnigakygrk atwigasgdq tffrideali
     1021 nshilatsei faskhiiglv ptsvsepppf kcllinkldg scrtfndseq edlqgfglcl
     1081 dpvydviwrf lpatremccy naviadarvp tasdiqalcs ilspelalps gshasttrsh
     1141 galhilgcld tlaamqelkm cvasaeeetq avmkvysked ysvvnrfesh gggwgysahs
     1201 veairfcada dillgglglf ggrgeytaki klfelgpdgg dhetdgdlla etdvlaydca
     1261 arekyammfd epvllqlgww yvawarvsgp ssdcgshgqa tittddgvvf qfksskksnn
     1321 gtdvnagqip qllyrlpsnd gnaskgkqqt sepvhilkrs fartvsvdcf esllsvlhws
     1381 wttlvlgvee lrglkgfqft atlldlerlr fvgtcclrll rvyiceifpi sastkavvee
     1441 ssklaecvgk trsllkkils egmdncltkl dndpqgylsq pltlleavlq echntftacf
     1501 hsfyptpalq waclcdllnc ldqdiqeanf rtsssrllaa vmsalcntsv kltsvlpiay
     1561 dgevllrslv kqvsiendsa lahrfpllva hmeklshtee nlmgmttfre vlekmlvivv
     1621 lpvrkslrke velfsphlvs ntcgllasiv seltasalgs evdglnslhs vkstpnrftk
     1681 tsqgrswntg ngspdaicft vdkpgvvlvg fcvyggggih eyelevladd aqtehpgdsa
     1741 hshrwtslel vkgtystdds psdiaeirld kavplkenvk yavrlrnygs rtangdggit
     1801 tvqcsdgvsf tfstcslssn gtnqtrgqvp qilyyrseyd gdlqsqllsk aneedkncsr
     1861 alsvvsvvvr aakdllhraf avdvedipel lsssslfsml lplilayigp vaasvpkaav
     1921 evfglvqell pavsalnqky appafnpnqs tdsttgnqpe qglsacttsn hyaviesdhp
     1981 ykqaavtqyk vsfpdcvrwv tiefdpqcgt aqpedvlrll ipsrsmhfsg lgskslahet
     2041 inswtelkkf sgstgwptsv lvlpgneahf sletasdyvk dekacfygfk cvavgyefnp
     2101 gldegiiqle kelsylgsvc aaalmkkdla lpigneleed leileeaslq vckahsgllg
     2161 kglalthspt ilealegnlp lhlqtnehsf ledfitcvqn ssggrlarwl qpdsyadpqk
     2221 tslilnkddi rcgwpttvvv qtkdqygdvv hvpnmkvevk avpvsqkksi qqenmkklqr
     2281 lpgsssnsts gtdltygghp ppkleatyep miikearyia itmmkayeny sfeelrfasp
     2341 tpkrpsenml irantdgtys anwtpgavgl ytihvtidgi eidaglevev kdppkgmipp
     2401 gtqmvkpkae pqpckvrkfv akdsaglrvr shpslqseqi givqvngtit fideihnddg
     2461 vwlrlndetv kkyvpnmngy ieawclsfnq hlgrsllvpv dnifstsqgv rdidflswtt
     2521 ltcfpqegrs nlddygkets ghpsqdanvg dlgtgqgggp glykvvktgp sghnirscpn
     2581 lrgipigmlv lgnkvkavge vinpegtwvq ldknsvvefc esddgeawsl ardrggnqyl
     2641 rheeeqvile hgaqtpppsp fsvqafnrgm dssgaqgfdy ginnkgdrls ailnsiqsgp
     2701 flptpsifeq aakppsslvh spfvfgqsls qqpqphpqlp nassrslasr ervhksnatg
     2761 pgttlsslvl rqkgdrdnla srsmspgskh rqesrssktd shssrsvdqv ksknndslsa
     2821 sealclksdt gklrsdshsr shspnhntlq alkadgrnsg lraespnpgs rssspkqktt
     2881 ssgrsspstn ssprsssphd knlpakvsps kahldpprer sksdsytldp dtlrkkkvpf
     2941 meplrgrsts pkpkmspkes kggssnsenr apsphvvqen lhsevvevcr sstllsndea
     3001 ndenaelhna eegsskvhfs igkapvkeel esrsspkvsr ktssrhvrpk kdksgplfkg
     3061 envrptepak qamspsvaec aravfaaflw hegivhdama cssflkfnpe ltkehapirn
     3121 slscqqglee kesklknrhs leissalnmf nisphgpdis kmgsinknkv lsmlkepplp
     3181 ekcedgksea vsyemtshss mrsksilplt lqhlvafwed ismatikaat qnmifpspgs
     3241 sailkkkene kdskktkkek kkkekaevrp rgnlfgemaq lamggpekdt icelcgeshp
     3301 ypvtyhmrqa hpgcgryagg qgynsighfc ggwagncgdg giggstwylv cdrcrekylr
     3361 ekqtaarekv kqsrkkplqv ktpralptme ahqviranal yllslssaae psllchhppk
     3421 pfhahlpslk egvseelpnk mgclylqtla rqhtenfgay qddnlfqdem rylrstsvpa
     3481 pyisvtpdac pnvfeepgsn mksmppslet spitdsdtak rtvfqrsysv vaseydkqhs
     3541 ssparvkavp rrrvhsgdae vgssllrhps pelsrlisah gslskgernf qwpvlafviq
     3601 hhdlegleva mkhalrksac rvfameafnw llcnvtqtts lhdilwhfva sltpspfete
     3661 eeeeeenkgn kenleqekdl gvcehplsdi liageaahpl phtfhrllqt isdlmmslps
     3721 gsslqqmalr cwslkfkqsd hqflhqsnvf hhinnilsks ddgdseesfn isvqsgyeai
     3781 sqelcvvtcl kdltsvvdik tssrpamigs ltdgstetfw esgdedknkt ksitiscvkg
     3841 inasyvsvhv dnsrdignkv tsliflcgka vedicrikqi dldsrhmgwv tselpggdhh
     3901 vikielkgpe ntlrvrqvkv lgwkegesik iagqisasvt qqknceaetl rvfrlitsqv
     3961 fgklicgdae ptpeqeeknl lsspegedka psdadlkehm vgiifsrskl tnlqkqvcah
     4021 ivqairmeat rvreewehai sskenansqp sdddassday cfellsmvla lsgsnvgrqy
     4081 laqqltllqd lfsllhtasp rvqrqvtsll rrvlpevtpm rlasvigvka lppadisdii
     4141 hsteksdwsk lgildmflgc iskaltvqlk akgttivgta gtaagkgvtt vtlpmifnss
     4201 yirrgishww mkgstppqia eiiiklvkdm aaghlsdaws rvtknaiaet iialtkmeee
     4261 hrcpvrciat trlwlalasl cvldqdhvdr lssgrwmgkd gqqkqmpmcd nhddgetaai
     4321 ilcnacgnlc tdcdrflhlh rrtrthqrqv fkeeeeaikv dlhegcgrtk lfwlmalads
     4381 ktmkamvefr ehtgkpasss sdvcrfcgtr ngtelsavgs vcsdqdcqey aklacskthp
     4441 cghpcggvkn eelclpclhg cdksatclkq daddmcmicf tealsaapai qmdcshvfhl
     4501 qctrrvlenr wlgpritfgf mscpicknki nhsvlkdlld pikelyedvr rkalmrleye
     4561 glhkseaitm sgarfynnpa gfamnryayy vcfkckkayf ggearcdaea gqgddydpre
     4621 licgacsdvs raqmcskhgt dfleykcryc csvavffcfg tthfcnachd dfqrmtsvpk
     4681 eelphcpagp kgkqlegsec plhvvhpptg eefalgcgvc rnahtf
//
LOCUS       XP_026128323            4714 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X10 [Carassius auratus].
ACCESSION   XP_026128323
VERSION     XP_026128323.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272538.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4714
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4714
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X10"
                     /calculated_mol_wt=516474
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4295..4343
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4461..4515
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4714
                     /gene="LOC113109035"
                     /coded_by="XM_026272538.1:448..14592"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdnifsts qgvrdidfls wttltcfpqe grsnlddygk
     2581 etsghpsqda nvgdlgtgqg ggpglykvvk tgpsghnirs cpnlrgipig mlvlgnkvka
     2641 vgevinpegt wvqldknsvv efcesddgea wslardrggn qylrheeeqv ilehgaqtpp
     2701 pspfsvqafn rgmdssgaqg fdyginnkda ssrslasrer vhksnatgpg ttlsslvlrq
     2761 kgdrdnlasr smspgskhrq esrssktdsh ssrsvdqvks knndslsase alclksdtgk
     2821 lrsdshsrsh spnhntlqal kadgrnsglr aespnpgsrs sspkqkttss grsspstnss
     2881 prsssphdkn lpakvspska hldpprersk sdsytldpdt lrkkkvpfme plrgrstspk
     2941 pkmspkeskg gssnsenrap sphvvqenlh sevvevcrss tllsndeand enaelhnaee
     3001 gsskvhfsig kapvkeeles rsspkvsrkt ssrhvrpkkd ksgplfkgen vrptepakqa
     3061 mspsvaecar avfaaflwhe givhdamacs sflkfnpelt kehapirnsl scqqgleeke
     3121 sklknrhsle issalnmfni sphgpdiskm gsinknkvls mlkepplpek cedgkseavs
     3181 yemtshssmr sksilpltlq hlvafwedis matikaatqn mifpspgssa ilkkkenekd
     3241 skktkkekkk kekaevrprg nlfgemaqla mggpekdtic elcgeshpyp vtyhmrqahp
     3301 gcgryaggqg ynsighfcgg wagncgdggi ggstwylvcd rcrekylrek qtaarekvkq
     3361 srkkplqvkt pralptmeah qviranalyl lslssaaeps llchhppkpf hahlpslkeg
     3421 vseelpnkmg clylqtlarq htenfgayqd dnlfqdemry lrstsvpapy isvtpdacpn
     3481 vfeepgsnmk smppsletsp itdsdtakrt vfqrsysvva seydkqhsss parvkavprr
     3541 rvhsgdaevg ssllrhpspe lsrlisahgs lskgernfqw pvlafviqhh dleglevamk
     3601 halrksacrv fameafnwll cnvtqttslh dilwhfvasl tpspfeteee eeeenkgnke
     3661 nleqekdlgv cehplsdili ageaahplph tfhrllqtis dlmmslpsgs slqqmalrcw
     3721 slkfkqsdhq flhqsnvfhh innilsksdd gdseesfnis vqsgyeaisq elcvvtclkd
     3781 ltsvvdikts srpamigslt dgstetfwes gdedknktks itiscvkgin asyvsvhvdn
     3841 srdignkvts liflcgkave dicrikqidl dsrhmgwvts elpggdhhvi kielkgpent
     3901 lrvrqvkvlg wkegesikia gqisasvtqq knceaetlrv frlitsqvfg klicgdaept
     3961 peqeeknlls spegedkaps dadlkehmvg iifsrskltn lqkqvcahiv qairmeatrv
     4021 reewehaiss kenansqpsd ddassdaycf ellsmvlals gsnvgrqyla qqltllqdlf
     4081 sllhtasprv qrqvtsllrr vlpevtpmrl asvigvkalp padisdiihs teksdwsklg
     4141 ildmflgcis kaltvqlkak gttivgtagt aagkgvttvt lpmifnssyi rrgishwwmk
     4201 gstppqiaei iiklvkdmaa ghlsdawsrv tknaiaetii altkmeeehr cpvrciattr
     4261 lwlalaslcv ldqdhvdrls sgrwmgkdgq qkqmpmcdnh ddgetaaiil cnacgnlctd
     4321 cdrflhlhrr trthqrqvfk eeeeaikvdl hegcgrtklf wlmaladskt mkamvefreh
     4381 tgkpassssd vcrfcgtrng telsavgsvc sdqdcqeyak lacskthpcg hpcggvknee
     4441 lclpclhgcd ksatclkqda ddmcmicfte alsaapaiqm dcshvfhlqc trrvlenrwl
     4501 gpritfgfms cpicknkinh svlkdlldpi kelyedvrrk almrleyegl hkseaitmsg
     4561 arfynnpagf amnryayyvc fkckkayfgg earcdaeagq gddydpreli cgacsdvsra
     4621 qmcskhgtdf leykcryccs vavffcfgtt hfcnachddf qrmtsvpkee lphcpagpkg
     4681 kqlegsecpl hvvhpptgee falgcgvcrn ahtf
//
LOCUS       XP_026128324            4708 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X11 [Carassius auratus].
ACCESSION   XP_026128324
VERSION     XP_026128324.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272539.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4708
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4708
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X11"
                     /calculated_mol_wt=515779
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4289..4337
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4455..4509
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4708
                     /gene="LOC113109035"
                     /coded_by="XM_026272539.1:448..14574"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdegrsnl ddygketsgh psqdanvgdl gtgqgggpgl
     2581 ykvinpegtw vqldknsvve fcesddgeaw slardrggnq ylrheeeqvi lehgaqtppp
     2641 spfsvqafnr gmdssgaqgf dyginnkgdr lsailnsiqs gpflptpsif eqaakppssl
     2701 vhspfvfgqs lsqqpqphpq lpnassrsla srervhksna tgpgttlssl vlrqkgdrdn
     2761 lasrsmspgs khrqesrssk tdshssrsvd qvksknndsl sasealclks dtgklrsdsh
     2821 srshspnhnt lqalkadgrn sglraespnp gsrssspkqk ttssgrssps tnssprsssp
     2881 hdknlpakvs pskahldppr ersksdsytl dpdtlrkkkv pfmeplrgrs tspkpkmspk
     2941 eskggssnse nrapsphvvq enlhsevvev crsstllsnd eandenaelh naeegsskvh
     3001 fsigkapvke elesrsspkv srktssrhvr pkkdksgplf kgenvrptep akqamspsva
     3061 ecaravfaaf lwhegivhda macssflkfn peltkehapi rnslscqqgl eekesklknr
     3121 hsleissaln mfnisphgpd iskmgsinkn kvlsmlkepp lpekcedgks eavsyemtsh
     3181 ssmrsksilp ltlqhlvafw edismatika atqnmifpsp gssailkkke nekdskktkk
     3241 ekkkkekaev rprgnlfgem aqlamggpek dticelcges hpypvtyhmr qahpgcgrya
     3301 ggqgynsigh fcggwagncg dggiggstwy lvcdrcreky lrekqtaare kvkqsrkkpl
     3361 qvktpralpt meahqviran alyllslssa aepsllchhp pkpfhahlps lkegvseelp
     3421 nkmgclylqt larqhtenfg ayqddnlfqd emrylrstsv papyisvtpd acpnvfeepg
     3481 snmksmppsl etspitdsdt akrtvfqrsy svvaseydkq hsssparvka vprrrvhsgd
     3541 aevgssllrh pspelsrlis ahgslskger nfqwpvlafv iqhhdlegle vamkhalrks
     3601 acrvfameaf nwllcnvtqt tslhdilwhf vasltpspfe teeeeeeenk gnkenleqek
     3661 dlgvcehpls diliageaah plphtfhrll qtisdlmmsl psgsslqqma lrcwslkfkq
     3721 sdhqflhqsn vfhhinnils ksddgdsees fnisvqsgye aisqelcvvt clkdltsvvd
     3781 iktssrpami gsltdgstet fwesgdedkn ktksitiscv kginasyvsv hvdnsrdign
     3841 kvtsliflcg kavedicrik qidldsrhmg wvtselpggd hhvikielkg pentlrvrqv
     3901 kvlgwkeges ikiagqisas vtqqknceae tlrvfrlits qvfgklicgd aeptpeqeek
     3961 nllsspeged kapsdadlke hmvgiifsrs kltnlqkqvc ahivqairme atrvreeweh
     4021 aisskenans qpsdddassd aycfellsmv lalsgsnvgr qylaqqltll qdlfsllhta
     4081 sprvqrqvts llrrvlpevt pmrlasvigv kalppadisd iihsteksdw sklgildmfl
     4141 gciskaltvq lkakgttivg tagtaagkgv ttvtlpmifn ssyirrgish wwmkgstppq
     4201 iaeiiiklvk dmaaghlsda wsrvtknaia etiialtkme eehrcpvrci attrlwlala
     4261 slcvldqdhv drlssgrwmg kdgqqkqmpm cdnhddgeta aiilcnacgn lctdcdrflh
     4321 lhrrtrthqr qvfkeeeeai kvdlhegcgr tklfwlmala dsktmkamve frehtgkpas
     4381 sssdvcrfcg trngtelsav gsvcsdqdcq eyaklacskt hpcghpcggv kneelclpcl
     4441 hgcdksatcl kqdaddmcmi cftealsaap aiqmdcshvf hlqctrrvle nrwlgpritf
     4501 gfmscpickn kinhsvlkdl ldpikelyed vrrkalmrle yeglhkseai tmsgarfynn
     4561 pagfamnrya yyvcfkckka yfggearcda eagqgddydp relicgacsd vsraqmcskh
     4621 gtdfleykcr yccsvavffc fgtthfcnac hddfqrmtsv pkeelphcpa gpkgkqlegs
     4681 ecplhvvhpp tgeefalgcg vcrnahtf
//
LOCUS       XP_026128325            4697 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X12 [Carassius auratus].
ACCESSION   XP_026128325
VERSION     XP_026128325.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272540.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4697
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4697
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X12"
                     /calculated_mol_wt=514021
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          4278..4326
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4444..4498
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4697
                     /gene="LOC113109035"
                     /coded_by="XM_026272540.1:448..14541"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideegr snlddygket sghpsqdanv
     2521 gdlgtgqggg pglykvvktg psghnirscp nlrgipigml vlgnkvkavg evinpegtwv
     2581 qldknsvvef cesddgeaws lardrggnqy lrheeeqvil ehgaqtppps pfsvqafnrg
     2641 mdssgaqgfd yginnkgdrl sailnsiqsg pflptpsife qaakppsslv hspfvfgqsl
     2701 sqqpqphpql pnassrslas rervhksnat gpgttlsslv lrqkgdrdnl asrsmspgsk
     2761 hrqesrsskt dshssrsvdq vksknndsls asealclksd tgklrsdshs rshspnhntl
     2821 qalkadgrns glraespnpg srssspkqkt tssgrsspst nssprsssph dknlpakvsp
     2881 skahldppre rsksdsytld pdtlrkkkvp fmeplrgrst spkpkmspke skggssnsen
     2941 rapsphvvqe nlhsevvevc rsstllsnde andenaelhn aeegsskvhf sigkapvkee
     3001 lesrsspkvs rktssrhvrp kkdksgplfk genvrptepa kqamspsvae caravfaafl
     3061 whegivhdam acssflkfnp eltkehapir nslscqqgle ekesklknrh sleissalnm
     3121 fnisphgpdi skmgsinknk vlsmlkeppl pekcedgkse avsyemtshs smrsksilpl
     3181 tlqhlvafwe dismatikaa tqnmifpspg ssailkkken ekdskktkke kkkkekaevr
     3241 prgnlfgema qlamggpekd ticelcgesh pypvtyhmrq ahpgcgryag gqgynsighf
     3301 cggwagncgd ggiggstwyl vcdrcrekyl rekqtaarek vkqsrkkplq vktpralptm
     3361 eahqvirana lyllslssaa epsllchhpp kpfhahlpsl kegvseelpn kmgclylqtl
     3421 arqhtenfga yqddnlfqde mrylrstsvp apyisvtpda cpnvfeepgs nmksmppsle
     3481 tspitdsdta krtvfqrsys vvaseydkqh sssparvkav prrrvhsgda evgssllrhp
     3541 spelsrlisa hgslskgern fqwpvlafvi qhhdleglev amkhalrksa crvfameafn
     3601 wllcnvtqtt slhdilwhfv asltpspfet eeeeeeenkg nkenleqekd lgvcehplsd
     3661 iliageaahp lphtfhrllq tisdlmmslp sgsslqqmal rcwslkfkqs dhqflhqsnv
     3721 fhhinnilsk sddgdseesf nisvqsgyea isqelcvvtc lkdltsvvdi ktssrpamig
     3781 sltdgstetf wesgdedknk tksitiscvk ginasyvsvh vdnsrdignk vtsliflcgk
     3841 avedicrikq idldsrhmgw vtselpggdh hvikielkgp entlrvrqvk vlgwkegesi
     3901 kiagqisasv tqqknceaet lrvfrlitsq vfgklicgda eptpeqeekn llsspegedk
     3961 apsdadlkeh mvgiifsrsk ltnlqkqvca hivqairmea trvreeweha isskenansq
     4021 psdddassda ycfellsmvl alsgsnvgrq ylaqqltllq dlfsllhtas prvqrqvtsl
     4081 lrrvlpevtp mrlasvigvk alppadisdi ihsteksdws klgildmflg ciskaltvql
     4141 kakgttivgt agtaagkgvt tvtlpmifns syirrgishw wmkgstppqi aeiiiklvkd
     4201 maaghlsdaw srvtknaiae tiialtkmee ehrcpvrcia ttrlwlalas lcvldqdhvd
     4261 rlssgrwmgk dgqqkqmpmc dnhddgetaa iilcnacgnl ctdcdrflhl hrrtrthqrq
     4321 vfkeeeeaik vdlhegcgrt klfwlmalad sktmkamvef rehtgkpass ssdvcrfcgt
     4381 rngtelsavg svcsdqdcqe yaklacskth pcghpcggvk neelclpclh gcdksatclk
     4441 qdaddmcmic ftealsaapa iqmdcshvfh lqctrrvlen rwlgpritfg fmscpicknk
     4501 inhsvlkdll dpikelyedv rrkalmrley eglhkseait msgarfynnp agfamnryay
     4561 yvcfkckkay fggearcdae agqgddydpr elicgacsdv sraqmcskhg tdfleykcry
     4621 ccsvavffcf gtthfcnach ddfqrmtsvp keelphcpag pkgkqlegse cplhvvhppt
     4681 geefalgcgv crnahtf
//
LOCUS       XP_026128327            4681 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X13 [Carassius auratus].
ACCESSION   XP_026128327
VERSION     XP_026128327.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272542.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4681
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4681
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X13"
                     /calculated_mol_wt=512981
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4262..4310
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4428..4482
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4681
                     /gene="LOC113109035"
                     /coded_by="XM_026272542.1:446..14491"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdnifsts qgvrdidfls wttltcfpqe grsnlddygk
     2581 etsghpsqda nvgdlgtgqg ggpglykvvk tgpsghnirs cpnlrgipig mlvlgnkvka
     2641 vgevinpegt wvqldknsvv efcesddgea wslardrggn qylrheeeqv ilehgaqtpp
     2701 pspfsvqafn rgmdssgaqg fdyginnkgd rdnlasrsms pgskhrqesr ssktdshssr
     2761 svdqvksknn dslsasealc lksdtgklrs dshsrshspn hntlqalkad grnsglraes
     2821 pnpgsrsssp kqkttssgrs spstnssprs ssphdknlpa kvspskahld pprersksds
     2881 ytldpdtlrk kkvpfmeplr grstspkpkm spkeskggss nsenrapsph vvqenlhsev
     2941 vevcrsstll sndeandena elhnaeegss kvhfsigkap vkeelesrss pkvsrktssr
     3001 hvrpkkdksg plfkgenvrp tepakqamsp svaecaravf aaflwhegiv hdamacssfl
     3061 kfnpeltkeh apirnslscq qgleekeskl knrhsleiss alnmfnisph gpdiskmgsi
     3121 nknkvlsmlk epplpekced gkseavsyem tshssmrsks ilpltlqhlv afwedismat
     3181 ikaatqnmif pspgssailk kkenekdskk tkkekkkkek aevrprgnlf gemaqlamgg
     3241 pekdticelc geshpypvty hmrqahpgcg ryaggqgyns ighfcggwag ncgdggiggs
     3301 twylvcdrcr ekylrekqta arekvkqsrk kplqvktpra lptmeahqvi ranalyllsl
     3361 ssaaepsllc hhppkpfhah lpslkegvse elpnkmgcly lqtlarqhte nfgayqddnl
     3421 fqdemrylrs tsvpapyisv tpdacpnvfe epgsnmksmp psletspitd sdtakrtvfq
     3481 rsysvvasey dkqhssspar vkavprrrvh sgdaevgssl lrhpspelsr lisahgslsk
     3541 gernfqwpvl afviqhhdle glevamkhal rksacrvfam eafnwllcnv tqttslhdil
     3601 whfvasltps pfeteeeeee enkgnkenle qekdlgvceh plsdiliage aahplphtfh
     3661 rllqtisdlm mslpsgsslq qmalrcwslk fkqsdhqflh qsnvfhhinn ilsksddgds
     3721 eesfnisvqs gyeaisqelc vvtclkdlts vvdiktssrp amigsltdgs tetfwesgde
     3781 dknktksiti scvkginasy vsvhvdnsrd ignkvtslif lcgkavedic rikqidldsr
     3841 hmgwvtselp ggdhhvikie lkgpentlrv rqvkvlgwke gesikiagqi sasvtqqknc
     3901 eaetlrvfrl itsqvfgkli cgdaeptpeq eeknllsspe gedkapsdad lkehmvgiif
     3961 srskltnlqk qvcahivqai rmeatrvree wehaissken ansqpsddda ssdaycfell
     4021 smvlalsgsn vgrqylaqql tllqdlfsll htasprvqrq vtsllrrvlp evtpmrlasv
     4081 igvkalppad isdiihstek sdwsklgild mflgciskal tvqlkakgtt ivgtagtaag
     4141 kgvttvtlpm ifnssyirrg ishwwmkgst ppqiaeiiik lvkdmaaghl sdawsrvtkn
     4201 aiaetiialt kmeeehrcpv rciattrlwl alaslcvldq dhvdrlssgr wmgkdgqqkq
     4261 mpmcdnhddg etaaiilcna cgnlctdcdr flhlhrrtrt hqrqvfkeee eaikvdlheg
     4321 cgrtklfwlm aladsktmka mvefrehtgk passssdvcr fcgtrngtel savgsvcsdq
     4381 dcqeyaklac skthpcghpc ggvkneelcl pclhgcdksa tclkqdaddm cmicfteals
     4441 aapaiqmdcs hvfhlqctrr vlenrwlgpr itfgfmscpi cknkinhsvl kdlldpikel
     4501 yedvrrkalm rleyeglhks eaitmsgarf ynnpagfamn ryayyvcfkc kkayfggear
     4561 cdaeagqgdd ydprelicga csdvsraqmc skhgtdfley kcryccsvav ffcfgtthfc
     4621 nachddfqrm tsvpkeelph cpagpkgkql egsecplhvv hpptgeefal gcgvcrnaht
     4681 f
//
LOCUS       XP_026128328            4670 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X14 [Carassius auratus].
ACCESSION   XP_026128328
VERSION     XP_026128328.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272543.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4670
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4670
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X14"
                     /calculated_mol_wt=511962
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4251..4299
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4417..4471
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4670
                     /gene="LOC113109035"
                     /coded_by="XM_026272543.1:447..14459"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdvinpeg twvqldknsv vefcesddge awslardrgg
     2581 nqylrheeeq vilehgaqtp ppspfsvqaf nrgmdssgaq gfdyginnkg drlsailnsi
     2641 qsgpflptps ifeqaakpps slvhspfvfg qslsqqpqph pqlpnassrs lasrervhks
     2701 natgpgttls slvlrqkgdr dnlasrsmsp gskhrqesrs sktdshssrs vdqvksknnd
     2761 slsasealcl ksdtgklrsd shsrshspnh ntlqalkadg rnsglraesp npgsrssspk
     2821 qkttssgrss pstnssprss sphdknlpak vspskahldp prersksdsy tldpdtlrkk
     2881 kvpfmeplrg rstspkpkms pkeskggssn senrapsphv vqenlhsevv evcrsstlls
     2941 ndeandenae lhnaeegssk vhfsigkapv keelesrssp kvsrktssrh vrpkkdksgp
     3001 lfkgenvrpt epakqamsps vaecaravfa aflwhegivh damacssflk fnpeltkeha
     3061 pirnslscqq gleekesklk nrhsleissa lnmfnisphg pdiskmgsin knkvlsmlke
     3121 pplpekcedg kseavsyemt shssmrsksi lpltlqhlva fwedismati kaatqnmifp
     3181 spgssailkk kenekdskkt kkekkkkeka evrprgnlfg emaqlamggp ekdticelcg
     3241 eshpypvtyh mrqahpgcgr yaggqgynsi ghfcggwagn cgdggiggst wylvcdrcre
     3301 kylrekqtaa rekvkqsrkk plqvktpral ptmeahqvir analyllsls saaepsllch
     3361 hppkpfhahl pslkegvsee lpnkmgclyl qtlarqhten fgayqddnlf qdemrylrst
     3421 svpapyisvt pdacpnvfee pgsnmksmpp sletspitds dtakrtvfqr sysvvaseyd
     3481 kqhsssparv kavprrrvhs gdaevgssll rhpspelsrl isahgslskg ernfqwpvla
     3541 fviqhhdleg levamkhalr ksacrvfame afnwllcnvt qttslhdilw hfvasltpsp
     3601 feteeeeeee nkgnkenleq ekdlgvcehp lsdiliagea ahplphtfhr llqtisdlmm
     3661 slpsgsslqq malrcwslkf kqsdhqflhq snvfhhinni lsksddgdse esfnisvqsg
     3721 yeaisqelcv vtclkdltsv vdiktssrpa migsltdgst etfwesgded knktksitis
     3781 cvkginasyv svhvdnsrdi gnkvtslifl cgkavedicr ikqidldsrh mgwvtselpg
     3841 gdhhvikiel kgpentlrvr qvkvlgwkeg esikiagqis asvtqqknce aetlrvfrli
     3901 tsqvfgklic gdaeptpeqe eknllsspeg edkapsdadl kehmvgiifs rskltnlqkq
     3961 vcahivqair meatrvreew ehaisskena nsqpsdddas sdaycfells mvlalsgsnv
     4021 grqylaqqlt llqdlfsllh tasprvqrqv tsllrrvlpe vtpmrlasvi gvkalppadi
     4081 sdiihsteks dwsklgildm flgciskalt vqlkakgtti vgtagtaagk gvttvtlpmi
     4141 fnssyirrgi shwwmkgstp pqiaeiiikl vkdmaaghls dawsrvtkna iaetiialtk
     4201 meeehrcpvr ciattrlwla laslcvldqd hvdrlssgrw mgkdgqqkqm pmcdnhddge
     4261 taaiilcnac gnlctdcdrf lhlhrrtrth qrqvfkeeee aikvdlhegc grtklfwlma
     4321 ladsktmkam vefrehtgkp assssdvcrf cgtrngtels avgsvcsdqd cqeyaklacs
     4381 kthpcghpcg gvkneelclp clhgcdksat clkqdaddmc micftealsa apaiqmdcsh
     4441 vfhlqctrrv lenrwlgpri tfgfmscpic knkinhsvlk dlldpikely edvrrkalmr
     4501 leyeglhkse aitmsgarfy nnpagfamnr yayyvcfkck kayfggearc daeagqgddy
     4561 dprelicgac sdvsraqmcs khgtdfleyk cryccsvavf fcfgtthfcn achddfqrmt
     4621 svpkeelphc pagpkgkqle gsecplhvvh pptgeefalg cgvcrnahtf
//
LOCUS       XP_026128329            4658 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X15 [Carassius auratus].
ACCESSION   XP_026128329
VERSION     XP_026128329.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272544.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4658
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4658
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X15"
                     /calculated_mol_wt=509742
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          4239..4287
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4405..4459
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4658
                     /gene="LOC113109035"
                     /coded_by="XM_026272544.1:447..14423"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckeg
     2461 rsnlddygke tsghpsqdan vgdlgtgqgg gpglykvvkt gpsghnirsc pnlrgipigm
     2521 lvlgnkvkav gevinpegtw vqldknsvve fcesddgeaw slardrggnq ylrheeeqvi
     2581 lehgaqtppp spfsvqafnr gmdssgaqgf dyginnkgdr lsailnsiqs gpflptpsif
     2641 eqaakppssl vhspfvfgqs lsqqpqphpq lpnassrsla srervhksna tgpgttlssl
     2701 vlrqkgdrdn lasrsmspgs khrqesrssk tdshssrsvd qvksknndsl sasealclks
     2761 dtgklrsdsh srshspnhnt lqalkadgrn sglraespnp gsrssspkqk ttssgrssps
     2821 tnssprsssp hdknlpakvs pskahldppr ersksdsytl dpdtlrkkkv pfmeplrgrs
     2881 tspkpkmspk eskggssnse nrapsphvvq enlhsevvev crsstllsnd eandenaelh
     2941 naeegsskvh fsigkapvke elesrsspkv srktssrhvr pkkdksgplf kgenvrptep
     3001 akqamspsva ecaravfaaf lwhegivhda macssflkfn peltkehapi rnslscqqgl
     3061 eekesklknr hsleissaln mfnisphgpd iskmgsinkn kvlsmlkepp lpekcedgks
     3121 eavsyemtsh ssmrsksilp ltlqhlvafw edismatika atqnmifpsp gssailkkke
     3181 nekdskktkk ekkkkekaev rprgnlfgem aqlamggpek dticelcges hpypvtyhmr
     3241 qahpgcgrya ggqgynsigh fcggwagncg dggiggstwy lvcdrcreky lrekqtaare
     3301 kvkqsrkkpl qvktpralpt meahqviran alyllslssa aepsllchhp pkpfhahlps
     3361 lkegvseelp nkmgclylqt larqhtenfg ayqddnlfqd emrylrstsv papyisvtpd
     3421 acpnvfeepg snmksmppsl etspitdsdt akrtvfqrsy svvaseydkq hsssparvka
     3481 vprrrvhsgd aevgssllrh pspelsrlis ahgslskger nfqwpvlafv iqhhdlegle
     3541 vamkhalrks acrvfameaf nwllcnvtqt tslhdilwhf vasltpspfe teeeeeeenk
     3601 gnkenleqek dlgvcehpls diliageaah plphtfhrll qtisdlmmsl psgsslqqma
     3661 lrcwslkfkq sdhqflhqsn vfhhinnils ksddgdsees fnisvqsgye aisqelcvvt
     3721 clkdltsvvd iktssrpami gsltdgstet fwesgdedkn ktksitiscv kginasyvsv
     3781 hvdnsrdign kvtsliflcg kavedicrik qidldsrhmg wvtselpggd hhvikielkg
     3841 pentlrvrqv kvlgwkeges ikiagqisas vtqqknceae tlrvfrlits qvfgklicgd
     3901 aeptpeqeek nllsspeged kapsdadlke hmvgiifsrs kltnlqkqvc ahivqairme
     3961 atrvreeweh aisskenans qpsdddassd aycfellsmv lalsgsnvgr qylaqqltll
     4021 qdlfsllhta sprvqrqvts llrrvlpevt pmrlasvigv kalppadisd iihsteksdw
     4081 sklgildmfl gciskaltvq lkakgttivg tagtaagkgv ttvtlpmifn ssyirrgish
     4141 wwmkgstppq iaeiiiklvk dmaaghlsda wsrvtknaia etiialtkme eehrcpvrci
     4201 attrlwlala slcvldqdhv drlssgrwmg kdgqqkqmpm cdnhddgeta aiilcnacgn
     4261 lctdcdrflh lhrrtrthqr qvfkeeeeai kvdlhegcgr tklfwlmala dsktmkamve
     4321 frehtgkpas sssdvcrfcg trngtelsav gsvcsdqdcq eyaklacskt hpcghpcggv
     4381 kneelclpcl hgcdksatcl kqdaddmcmi cftealsaap aiqmdcshvf hlqctrrvle
     4441 nrwlgpritf gfmscpickn kinhsvlkdl ldpikelyed vrrkalmrle yeglhkseai
     4501 tmsgarfynn pagfamnrya yyvcfkckka yfggearcda eagqgddydp relicgacsd
     4561 vsraqmcskh gtdfleykcr yccsvavffc fgtthfcnac hddfqrmtsv pkeelphcpa
     4621 gpkgkqlegs ecplhvvhpp tgeefalgcg vcrnahtf
//
LOCUS       XP_026128330            4656 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X16 [Carassius auratus].
ACCESSION   XP_026128330
VERSION     XP_026128330.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272545.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4656
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4656
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X16"
                     /calculated_mol_wt=510122
     Region          574..1018
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1228..1378
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1719..1878
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2385..2436
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2468..2530
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4237..4285
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4403..4457
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4656
                     /gene="LOC113109035"
                     /coded_by="XM_026272545.1:445..14415"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllavpvppp
      841 pgvnieehtq irqeekrqri nrrhrleegr gplvfpgpll mnqreqvlar lrplqafklm
      901 reklkdgsse rgdkdaskit typpgavrfd celravqvsc gfhhsvvlme ngdvytfgyg
      961 qhgqlghgdv nsrgspslvq alpgpstqvt agsnhtavll tdgqvftfgs fskgqlgrpi
     1021 ldmpywnakp spmpnigaky grkatwigas gdqtffride alinshilat seifaskhii
     1081 glvptsvsep ppfkcllink ldgscrtfnd seqedlqgfg lcldpvydvi wrflpatrem
     1141 ccynaviada rvptasdiqa lcsilspela lpsgshastt rshgalhilg cldtlaamqe
     1201 lkmcvasaee etqavmkvys kedysvvnrf eshgggwgys ahsveairfc adadillggl
     1261 glfggrgeyt akiklfelgp dggdhetdgd llaetdvlay dcaarekyam mfdepvllql
     1321 gwwyvawarv sgpssdcgsh gqatittddg vvfqfksskk snngtdvnag qipqllyrlp
     1381 sndgnaskgk qqtsepvhil krsfartvsv dcfesllsvl hwswttlvlg veelrglkgf
     1441 qftatlldle rlrfvgtccl rllrvyicei fpisastkav veessklaec vgktrsllkk
     1501 ilsegmdncl tkldndpqgy lsqpltllea vlqechntft acfhsfyptp alqwaclcdl
     1561 lncldqdiqe anfrtsssrl laavmsalcn tsvkltsvlp iaydgevllr slvkqvsien
     1621 dsalahrfpl lvahmeklsh teenlmgmtt frevlekmlv ivvlpvrksl rkevelfsph
     1681 lvsntcglla sivseltasa lgsevdglns lhsvkstpnr ftktsqgrsw ntgngspdai
     1741 cftvdkpgvv lvgfcvyggg giheyelevl addaqtehpg dsahshrwts lelvkgtyst
     1801 ddspsdiaei rldkavplke nvkyavrlrn ygsrtangdg gittvqcsdg vsftfstcsl
     1861 ssngtnqtrg qvpqilyyrs eydgdlqsql lskaneedkn csralsvvsv vvraakdllh
     1921 rafavdvedi pellsssslf smllplilay igpvaasvpk aavevfglvq ellpavsaln
     1981 qkyappafnp nqstdsttgn qpeqglsact tsnhyavies dhpykqaavt qykvsfpdcv
     2041 rwvtiefdpq cgtaqpedvl rllipsrsmh fsglgsksla hetinswtel kkfsgstgwp
     2101 tsvlvlpgne ahfsletasd yvkdekacfy gfkcvavgye fnpgldegii qlekelsylg
     2161 svcaaalmkk dlalpignel eedleileea slqvckahsg llgkglalth sptilealeg
     2221 nlplhlqtne hsfledfitc vqnssggrla rwlqpdsyad pqktslilnk ddircgwptt
     2281 vvvqtkdqyg dvvhvpnmkv evkavpvsqk ksiqqenmkk lqrlpgsssn stsgtdltyg
     2341 ghpppkleat yepmiikear yiaitmmkay enysfeelrf asptpkrpse nmlirantdg
     2401 tysanwtpga vglytihvti dgieidagle vevkdppkgm ippgtqmvkp kaepqpckvr
     2461 kfvakdsagl rvrshpslqs eqigivqvng titfideihn ddgvwlrlnd etvkkyvpnm
     2521 ngyieawcls fnqhlgrsll vpvdegrsnl ddygketsgh psqdanvgdl gtgqgggpgl
     2581 ykvvktgpsg hnirscpnlr gipigmlvlg nkvkavgevi npegtwvqld knsvvefces
     2641 ddgeawslar drggnqylrh eeeqvilehg aqtpppspfs vqafnrgmds sgaqgfdygi
     2701 nnkgdrdnla srsmspgskh rqesrssktd shssrsvdqv ksknndslsa sealclksdt
     2761 gklrsdshsr shspnhntlq alkadgrnsg lraespnpgs rssspkqktt ssgrsspstn
     2821 ssprsssphd knlpakvsps kahldpprer sksdsytldp dtlrkkkvpf meplrgrsts
     2881 pkpkmspkes kggssnsenr apsphvvqen lhsevvevcr sstllsndea ndenaelhna
     2941 eegsskvhfs igkapvkeel esrsspkvsr ktssrhvrpk kdksgplfkg envrptepak
     3001 qamspsvaec aravfaaflw hegivhdama cssflkfnpe ltkehapirn slscqqglee
     3061 kesklknrhs leissalnmf nisphgpdis kmgsinknkv lsmlkepplp ekcedgksea
     3121 vsyemtshss mrsksilplt lqhlvafwed ismatikaat qnmifpspgs sailkkkene
     3181 kdskktkkek kkkekaevrp rgnlfgemaq lamggpekdt icelcgeshp ypvtyhmrqa
     3241 hpgcgryagg qgynsighfc ggwagncgdg giggstwylv cdrcrekylr ekqtaarekv
     3301 kqsrkkplqv ktpralptme ahqviranal yllslssaae psllchhppk pfhahlpslk
     3361 egvseelpnk mgclylqtla rqhtenfgay qddnlfqdem rylrstsvpa pyisvtpdac
     3421 pnvfeepgsn mksmppslet spitdsdtak rtvfqrsysv vaseydkqhs ssparvkavp
     3481 rrrvhsgdae vgssllrhps pelsrlisah gslskgernf qwpvlafviq hhdlegleva
     3541 mkhalrksac rvfameafnw llcnvtqtts lhdilwhfva sltpspfete eeeeeenkgn
     3601 kenleqekdl gvcehplsdi liageaahpl phtfhrllqt isdlmmslps gsslqqmalr
     3661 cwslkfkqsd hqflhqsnvf hhinnilsks ddgdseesfn isvqsgyeai sqelcvvtcl
     3721 kdltsvvdik tssrpamigs ltdgstetfw esgdedknkt ksitiscvkg inasyvsvhv
     3781 dnsrdignkv tsliflcgka vedicrikqi dldsrhmgwv tselpggdhh vikielkgpe
     3841 ntlrvrqvkv lgwkegesik iagqisasvt qqknceaetl rvfrlitsqv fgklicgdae
     3901 ptpeqeeknl lsspegedka psdadlkehm vgiifsrskl tnlqkqvcah ivqairmeat
     3961 rvreewehai sskenansqp sdddassday cfellsmvla lsgsnvgrqy laqqltllqd
     4021 lfsllhtasp rvqrqvtsll rrvlpevtpm rlasvigvka lppadisdii hsteksdwsk
     4081 lgildmflgc iskaltvqlk akgttivgta gtaagkgvtt vtlpmifnss yirrgishww
     4141 mkgstppqia eiiiklvkdm aaghlsdaws rvtknaiaet iialtkmeee hrcpvrciat
     4201 trlwlalasl cvldqdhvdr lssgrwmgkd gqqkqmpmcd nhddgetaai ilcnacgnlc
     4261 tdcdrflhlh rrtrthqrqv fkeeeeaikv dlhegcgrtk lfwlmalads ktmkamvefr
     4321 ehtgkpasss sdvcrfcgtr ngtelsavgs vcsdqdcqey aklacskthp cghpcggvkn
     4381 eelclpclhg cdksatclkq daddmcmicf tealsaapai qmdcshvfhl qctrrvlenr
     4441 wlgpritfgf mscpicknki nhsvlkdlld pikelyedvr rkalmrleye glhkseaitm
     4501 sgarfynnpa gfamnryayy vcfkckkayf ggearcdaea gqgddydpre licgacsdvs
     4561 raqmcskhgt dfleykcryc csvavffcfg tthfcnachd dfqrmtsvpk eelphcpagp
     4621 kgkqlegsec plhvvhpptg eefalgcgvc rnahtf
//
LOCUS       XP_026128331            4574 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase MYCBP2 isoform X17 [Carassius auratus].
ACCESSION   XP_026128331
VERSION     XP_026128331.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272546.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4574
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..4574
                     /product="E3 ubiquitin-protein ligase MYCBP2 isoform X17"
                     /calculated_mol_wt=501856
     Region          574..1010
                     /region_name="ATS1"
                     /note="Alpha-tubulin suppressor ATS1 and related RCC1
                     domain-containing proteins [Cell cycle control, cell
                     division, chromosome partitioning, Cytoskeleton]; COG5184"
                     /db_xref="CDD:444065"
     Region          1220..1370
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          1711..1870
                     /region_name="PHR"
                     /note="PHR domain; pfam08005"
                     /db_xref="CDD:462339"
     Region          <2377..2428
                     /region_name="IG_FLMN"
                     /note="Filamin-type immunoglobulin domains; smart00557"
                     /db_xref="CDD:214720"
     Region          2460..2522
                     /region_name="SH3_3"
                     /note="Bacterial SH3 domain; pfam08239"
                     /db_xref="CDD:462405"
     Region          4155..4203
                     /region_name="Bbox2_MYCBP2"
                     /note="B-box-type 2 zinc finger found in Myc-binding
                     protein 2 (MYCBP2) and similar proteins; cd19799"
                     /db_xref="CDD:380857"
     Region          4321..4375
                     /region_name="RING-H2_PHR"
                     /note="RING finger, H2 subclass, found in the PHR
                     (Pam/Highwire/RPM-1) protein family; cd16463"
                     /db_xref="CDD:438126"
     CDS             1..4574
                     /gene="LOC113109035"
                     /coded_by="XM_026272546.1:1..13725"
                     /db_xref="GeneID:113109035"
ORIGIN      
        1 mmcaaaaaga ggsgipssss hstgmgvrvi pgagnefasi gsgmgscpva gtrsdcrsry
       61 qlllsgrala eryrriytta itdkeqglhl grgkkvlskk klkrrqkvks kvktrtkset
      121 ldgafpvpdi klhsnpsafn vycnvrhcvl dwqqkeaala lasrnsvqsg dsdseeeeey
      181 repaiklpki igiglcgvfe liketrfshp slclrslqal ldmlqgqqpe sfqteppdvl
      241 eslfhlllet tvrstgmndp tgqtltalsc aclfslvvaw gdtgkilqav sailtnngsh
      301 acqtiqvpti lnalqrsvqa vlvgkiqiqd wfgngikraa lmnkwvlkev nidedercll
      361 qtdgsflyll ckdglykvgs gysgtvrghv ynstsrirnr kekrswlgfa qgcllyrdmn
      421 shsmaaikin petleqegti tmpglqadgq niiftdgeyi nqiaackddg fvvriyatss
      481 dpalqqelql klarkclhac gislfdlekd lhiistgfde eaaligagre falmktasgk
      541 iyytgkyqsl gikqggpsag kwvelpvtks pkivqfsvgh dgshallvae dgsvfftgsa
      601 skgedgestk srrqpkpykp kkmikletkt aiytacnngs ssivtkdgel ymfgkdavys
      661 dstsqvsdlk ghfvtqvamg kahtcvltks gevwtfgvnn kgqcgrdtga msqagkafgv
      721 enmatamded ledeldekee ksmmcqpgmh kwkldqcmvc tvcgdctgyg ascvssgrpd
      781 rapggicgcg sgesgcsscg cckacareld gqearqrgif davkemipld lllgvnieeh
      841 tqirqeekrq rinrrhrlee grgplvfpgp llmnqreqvl arlrplqafk lmreklkdgs
      901 sergdkdask ittyppgavr fdcelravqv scgfhhsvvl mengdvytfg ygqhgqlghg
      961 dvnsrgspsl vqalpgpstq vtagsnhtav lltdgqvftf gsfskgqlgr pildmpywna
     1021 kpspmpniga kygrkatwig asgdqtffri dealinshil atseifaskh iiglvptsvs
     1081 epppfkclli nkldgscrtf ndseqedlqg fglcldpvyd viwrflpatr emccynavia
     1141 darvptasdi qalcsilspe lalpsgshas ttrshgalhi lgcldtlaam qelkmcvasa
     1201 eeetqavmkv yskedysvvn rfeshgggwg ysahsveair fcadadillg glglfggrge
     1261 ytakiklfel gpdggdhetd gdllaetdvl aydcaareky ammfdepvll qlgwwyvawa
     1321 rvsgpssdcg shgqatittd dgvvfqfkss kksnngtdvn agqipqllyr lpsndgnask
     1381 gkqqtsepvh ilkrsfartv svdcfeslls vlhwswttlv lgveelrglk gfqftatlld
     1441 lerlrfvgtc clrllrvyic eifpisastk avveesskla ecvgktrsll kkilsegmdn
     1501 cltkldndpq gylsqpltll eavlqechnt ftacfhsfyp tpalqwaclc dllncldqdi
     1561 qeanfrtsss rllaavmsal cntsvkltsv lpiaydgevl lrslvkqvsi endsalahrf
     1621 pllvahmekl shteenlmgm ttfrevlekm lvivvlpvrk slrkevelfs phlvsntcgl
     1681 lasivselta salgsevdgl nslhsvkstp nrftktsqgr swntgngspd aicftvdkpg
     1741 vvlvgfcvyg gggiheyele vladdaqteh pgdsahshrw tslelvkgty stddspsdia
     1801 eirldkavpl kenvkyavrl rnygsrtang dggittvqcs dgvsftfstc slssngtnqt
     1861 rgqvpqilyy rseydgdlqs qllskaneed kncsralsvv svvvraakdl lhrafavdve
     1921 dipellssss lfsmllplil ayigpvaasv pkaavevfgl vqellpavsa lnqkyappaf
     1981 npnqstdstt gnqpeqglsa cttsnhyavi esdhpykqaa vtqykvsfpd cvrwvtiefd
     2041 pqcgtaqped vlrllipsrs mhfsglgsks lahetinswt elkkfsgstg wptsvlvlpg
     2101 neahfsleta sdyvkdekac fygfkcvavg yefnpgldeg iiqlekelsy lgsvcaaalm
     2161 kkdlalpign eleedleile easlqvckah sgllgkglal thsptileal egnlplhlqt
     2221 nehsfledfi tcvqnssggr larwlqpdsy adpqktslil nkddircgwp ttvvvqtkdq
     2281 ygdvvhvpnm kvevkavpvs qkksiqqenm kklqrlpgss snstsgtdlt ygghpppkle
     2341 atyepmiike aryiaitmmk ayenysfeel rfasptpkrp senmlirant dgtysanwtp
     2401 gavglytihv tidgieidag levevkdppk gmippgtqmv kpkaepqpck vrkfvakdsa
     2461 glrvrshpsl qseqigivqv ngtitfidei hnddgvwlrl ndetvkkyvp nmngyieawc
     2521 lsfnqhlgrs llvpvdvinp egtwvqldkn svvefcesdd geawslardr ggnqylrhee
     2581 eqvilehgaq tpppspfsvq afnrgmdssg aqgfdyginn kgdrdnlasr smspgskhrq
     2641 esrssktdsh ssrsvdqvks knndslsase alclksdtgk lrsdshsrsh spnhntlqal
     2701 kadgrnsglr aespnpgsrs sspkqkttss grsspstnss prsssphdkn lpakvspska
     2761 hldpprersk sdsytldpdt lrkkkvpfme plrgrstspk pkmspkeskg gssnsenrap
     2821 sphvvqenlh sevvevcrss tllsndeand enaelhnaee gsskvhfsig kapvkeeles
     2881 rsspkvsrkt ssrhvrpkkd ksgplfkgen vrptepakqa mspsvaecar avfaaflwhe
     2941 givhdamacs sflkfnpelt kehapirnsl scqqgleeke sklknrhsle issalnmfni
     3001 sphgpdiskm gsinknkvls mlkepplpek cedgkseavs yemtshssmr sksilpltlq
     3061 hlvafwedis matikaatqn mifpspgssa ilkkkenekd skktkkekkk kekaevrprg
     3121 nlfgemaqla mggpekdtic elcgeshpyp vtyhmrqahp gcgryaggqg ynsighfcgg
     3181 wagncgdggi ggstwylvcd rcrekylrek qtaarekvkq srkkplqvkt pralptmeah
     3241 qviranalyl lslssaaeps llchhppkpf hahlpslkeg vseelpnkmg clylqtlarq
     3301 htenfgayqd dnlfqdemry lrstsvpapy isvtpdacpn vfeepgsnmk smppsletsp
     3361 itdsdtakrt vfqrsysvva seydkqhsss parvkavprr rvhsgdaevg ssllrhpspe
     3421 lsrlisahgs lskgernfqw pvlafviqhh dleglevamk halrksacrv fameafnwll
     3481 cnvtqttslh dilwhfvasl tpspfeteee eeeenkgnke nleqekdlgv cehplsdili
     3541 ageaahplph tfhrllqtis dlmmslpsgs slqqmalrcw slkfkqsdhq flhqsnvfhh
     3601 innilsksdd gdseesfnis vqsgyeaisq elcvvtclkd ltsvvdikts srpamigslt
     3661 dgstetfwes gdedknktks itiscvkgin asyvsvhvdn srdignkvts liflcgkave
     3721 dicrikqidl dsrhmgwvts elpggdhhvi kielkgpent lrvrqvkvlg wkegesikia
     3781 gqisasvtqq knceaetlrv frlitsqvfg klicgdaept peqeeknlls spegedkaps
     3841 dadlkehmvg iifsrskltn lqkqvcahiv qairmeatrv reewehaiss kenansqpsd
     3901 ddassdaycf ellsmvlals gsnvgrqyla qqltllqdlf sllhtasprv qrqvtsllrr
     3961 vlpevtpmrl asvigvkalp padisdiihs teksdwsklg ildmflgcis kaltvqlkak
     4021 gttivgtagt aagkgvttvt lpmifnssyi rrgishwwmk gstppqiaei iiklvkdmaa
     4081 ghlsdawsrv tknaiaetii altkmeeehr cpvrciattr lwlalaslcv ldqdhvdrls
     4141 sgrwmgkdgq qkqmpmcdnh ddgetaaiil cnacgnlctd cdrflhlhrr trthqrqvfk
     4201 eeeeaikvdl hegcgrtklf wlmaladskt mkamvefreh tgkpassssd vcrfcgtrng
     4261 telsavgsvc sdqdcqeyak lacskthpcg hpcggvknee lclpclhgcd ksatclkqda
     4321 ddmcmicfte alsaapaiqm dcshvfhlqc trrvlenrwl gpritfgfms cpicknkinh
     4381 svlkdlldpi kelyedvrrk almrleyegl hkseaitmsg arfynnpagf amnryayyvc
     4441 fkckkayfgg earcdaeagq gddydpreli cgacsdvsra qmcskhgtdf leykcryccs
     4501 vavffcfgtt hfcnachddf qrmtsvpkee lphcpagpkg kqlegsecpl hvvhpptgee
     4561 falgcgvcrn ahtf
//
LOCUS       XP_026128332             431 aa            linear   VRT 18-JUN-2025
DEFINITION  F-box/LRR-repeat protein 3-like [Carassius auratus].
ACCESSION   XP_026128332
VERSION     XP_026128332.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272547.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..431
                     /product="F-box/LRR-repeat protein 3-like"
                     /calculated_mol_wt=48957
     Region          38..80
                     /region_name="F-box_SF"
                     /note="F-box domain superfamily; cl45894"
                     /db_xref="CDD:459239"
     Site            order(43..44,46..48,51..52,55,66..68,70,73)
                     /site_type="other"
                     /note="F-box motif"
                     /db_xref="CDD:438852"
     Site            order(43,47,50..51,54..55,59,61..62,66..68,70)
                     /site_type="other"
                     /note="Skp1 binding site [polypeptide binding]"
                     /db_xref="CDD:438852"
     Region          83..431
                     /region_name="FBXL3_LRR-like"
                     /note="Leucine-rich repeat domain of FBXL3 and related
                     proteins; cl45928"
                     /db_xref="CDD:480268"
     Site            order(86,96..97,99,101..102,105)
                     /site_type="other"
                     /note="SKP1 interface [polypeptide binding]"
                     /db_xref="CDD:467830"
     Site            order(123,149..152,185,211,258,260,262,264..265,291,295,
                     297,315,317,319..320,339,341..343,346,367..371,392,394,
                     396,409,426..429)
                     /site_type="other"
                     /note="CRY2 interface [polypeptide binding]"
                     /db_xref="CDD:467830"
     Region          178..203
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          204..229
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          230..255
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          256..291
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          292..336
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          337..363
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          364..389
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..431
                     /gene="LOC113109037"
                     /coded_by="XM_026272547.1:344..1639"
                     /db_xref="GeneID:113109037"
ORIGIN      
        1 mkrrlsrere dspsscegpt dsckrvrqpt edsgdlppdw arlpqeillh ifqflplldr
       61 afasqvcrgw neafhmpelw rcfefelnqp assylkathp dlikqiikrh snhlqyvsfk
      121 vdsstesaea acdilsqlvn cslktlglis tarpsfmelp kshfisaltv vfvnskslss
      181 lkiddtpvdd pslkvlvann sdtlkllkms scphvspagi lcvadqchgl relalnyhll
      241 sdelllalss ekhvhlehlr idvvsenpgq qfhtikkssw damvrhspkf nlvmyfflye
      301 defgpffrde ipvthlyfgr svskevlgrv gmncprlvel vvcanglrpl deeliriaer
      361 cqhlsaiglg ecevscsafv efvkmcgrrl sqlsimeevl ipdhkyslde ihwevskhlg
      421 rvwfpdmmpt w
//
LOCUS       XP_026128333             431 aa            linear   VRT 18-JUN-2025
DEFINITION  F-box/LRR-repeat protein 3-like [Carassius auratus].
ACCESSION   XP_026128333
VERSION     XP_026128333.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272548.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..431
                     /product="F-box/LRR-repeat protein 3-like"
                     /calculated_mol_wt=48957
     Region          38..80
                     /region_name="F-box_SF"
                     /note="F-box domain superfamily; cl45894"
                     /db_xref="CDD:459239"
     Site            order(43..44,46..48,51..52,55,66..68,70,73)
                     /site_type="other"
                     /note="F-box motif"
                     /db_xref="CDD:438852"
     Site            order(43,47,50..51,54..55,59,61..62,66..68,70)
                     /site_type="other"
                     /note="Skp1 binding site [polypeptide binding]"
                     /db_xref="CDD:438852"
     Region          83..431
                     /region_name="FBXL3_LRR-like"
                     /note="Leucine-rich repeat domain of FBXL3 and related
                     proteins; cl45928"
                     /db_xref="CDD:480268"
     Site            order(86,96..97,99,101..102,105)
                     /site_type="other"
                     /note="SKP1 interface [polypeptide binding]"
                     /db_xref="CDD:467830"
     Site            order(123,149..152,185,211,258,260,262,264..265,291,295,
                     297,315,317,319..320,339,341..343,346,367..371,392,394,
                     396,409,426..429)
                     /site_type="other"
                     /note="CRY2 interface [polypeptide binding]"
                     /db_xref="CDD:467830"
     Region          178..203
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          204..229
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          230..255
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          256..291
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          292..336
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          337..363
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          364..389
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..431
                     /gene="LOC113109037"
                     /coded_by="XM_026272548.1:319..1614"
                     /db_xref="GeneID:113109037"
ORIGIN      
        1 mkrrlsrere dspsscegpt dsckrvrqpt edsgdlppdw arlpqeillh ifqflplldr
       61 afasqvcrgw neafhmpelw rcfefelnqp assylkathp dlikqiikrh snhlqyvsfk
      121 vdsstesaea acdilsqlvn cslktlglis tarpsfmelp kshfisaltv vfvnskslss
      181 lkiddtpvdd pslkvlvann sdtlkllkms scphvspagi lcvadqchgl relalnyhll
      241 sdelllalss ekhvhlehlr idvvsenpgq qfhtikkssw damvrhspkf nlvmyfflye
      301 defgpffrde ipvthlyfgr svskevlgrv gmncprlvel vvcanglrpl deeliriaer
      361 cqhlsaiglg ecevscsafv efvkmcgrrl sqlsimeevl ipdhkyslde ihwevskhlg
      421 rvwfpdmmpt w
//
LOCUS       XP_026128334             431 aa            linear   VRT 18-JUN-2025
DEFINITION  F-box/LRR-repeat protein 3-like [Carassius auratus].
ACCESSION   XP_026128334
VERSION     XP_026128334.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272549.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..431
                     /product="F-box/LRR-repeat protein 3-like"
                     /calculated_mol_wt=48957
     Region          38..80
                     /region_name="F-box_SF"
                     /note="F-box domain superfamily; cl45894"
                     /db_xref="CDD:459239"
     Site            order(43..44,46..48,51..52,55,66..68,70,73)
                     /site_type="other"
                     /note="F-box motif"
                     /db_xref="CDD:438852"
     Site            order(43,47,50..51,54..55,59,61..62,66..68,70)
                     /site_type="other"
                     /note="Skp1 binding site [polypeptide binding]"
                     /db_xref="CDD:438852"
     Region          83..431
                     /region_name="FBXL3_LRR-like"
                     /note="Leucine-rich repeat domain of FBXL3 and related
                     proteins; cl45928"
                     /db_xref="CDD:480268"
     Site            order(86,96..97,99,101..102,105)
                     /site_type="other"
                     /note="SKP1 interface [polypeptide binding]"
                     /db_xref="CDD:467830"
     Site            order(123,149..152,185,211,258,260,262,264..265,291,295,
                     297,315,317,319..320,339,341..343,346,367..371,392,394,
                     396,409,426..429)
                     /site_type="other"
                     /note="CRY2 interface [polypeptide binding]"
                     /db_xref="CDD:467830"
     Region          178..203
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          204..229
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          230..255
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          256..291
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          292..336
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          337..363
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          364..389
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..431
                     /gene="LOC113109037"
                     /coded_by="XM_026272549.1:112..1407"
                     /db_xref="GeneID:113109037"
ORIGIN      
        1 mkrrlsrere dspsscegpt dsckrvrqpt edsgdlppdw arlpqeillh ifqflplldr
       61 afasqvcrgw neafhmpelw rcfefelnqp assylkathp dlikqiikrh snhlqyvsfk
      121 vdsstesaea acdilsqlvn cslktlglis tarpsfmelp kshfisaltv vfvnskslss
      181 lkiddtpvdd pslkvlvann sdtlkllkms scphvspagi lcvadqchgl relalnyhll
      241 sdelllalss ekhvhlehlr idvvsenpgq qfhtikkssw damvrhspkf nlvmyfflye
      301 defgpffrde ipvthlyfgr svskevlgrv gmncprlvel vvcanglrpl deeliriaer
      361 cqhlsaiglg ecevscsafv efvkmcgrrl sqlsimeevl ipdhkyslde ihwevskhlg
      421 rvwfpdmmpt w
//
LOCUS       XP_026128335             319 aa            linear   VRT 18-JUN-2025
DEFINITION  ceroid-lipofuscinosis neuronal protein 5 [Carassius auratus].
ACCESSION   XP_026128335
VERSION     XP_026128335.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272550.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..319
                     /product="ceroid-lipofuscinosis neuronal protein 5"
                     /calculated_mol_wt=37011
     Region          26..319
                     /region_name="CLN5"
                     /note="Ceroid-lipofuscinosis neuronal protein 5;
                     pfam15014"
                     /db_xref="CDD:464446"
     CDS             1..319
                     /gene="cln5"
                     /coded_by="XM_026272550.1:129..1088"
                     /db_xref="GeneID:113109038"
ORIGIN      
        1 mkslvffcwi vgslsgqqlw pvpyerldrr pdvdpycqal ypfcpsgdpd gripvmtdsd
       61 iisvfrlqtp vwefkygdml gkfhimhdav gfgsartgrn ftmewyelfq lgnctfpher
      121 asvsapfwcn qgaacfyegi ddihwkqngt lekigeisge vfnemarwvq ednktgvyye
      181 twtvksdasa nattwfesyd csqfvhrtyk kllglgaels sqtptyytki ylfsgepvhl
      241 gndsifqqss tkdlatdikk ffhsfrshqs fvemieslle afekvvlekt fyfyynseyw
      301 klpmkypyik itfeeiplp
//
LOCUS       XP_026128336             223 aa            linear   VRT 18-JUN-2025
DEFINITION  radial spoke head 1 homolog isoform X1 [Carassius auratus].
ACCESSION   XP_026128336
VERSION     XP_026128336.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272551.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..223
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..223
                     /product="radial spoke head 1 homolog isoform X1"
                     /calculated_mol_wt=25526
     Region          <3..175
                     /region_name="COG4642"
                     /note="Uncharacterized conserved protein [Function
                     unknown]"
                     /db_xref="CDD:443680"
     CDS             1..223
                     /gene="LOC113109040"
                     /coded_by="XM_026272551.1:101..772"
                     /db_xref="GeneID:113109040"
ORIGIN      
        1 msdagseefd eeqgslgeye gdrneagerh gkgravlpkg dtyqgayetg krcgqgtykf
       61 kkgaryigew ymnlkhgegv fyypdgskye gswvddqrqg hgvytypngd tydgewlhhq
      121 rhgqgtythh etgsqymgtw vmgkmastgq lihlnhryqg nfvnnnpsgp gkyvfdigce
      181 qhgeyfqlep ikrwwksekd iqtvrntehq kmikkrgppv hyi
//
LOCUS       XP_026128337             217 aa            linear   VRT 18-JUN-2025
DEFINITION  radial spoke head 1 homolog isoform X2 [Carassius auratus].
ACCESSION   XP_026128337
VERSION     XP_026128337.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272552.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..217
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..217
                     /product="radial spoke head 1 homolog isoform X2"
                     /calculated_mol_wt=24472
     Region          <3..175
                     /region_name="COG4642"
                     /note="Uncharacterized conserved protein [Function
                     unknown]"
                     /db_xref="CDD:443680"
     CDS             1..217
                     /gene="LOC113109040"
                     /coded_by="XM_026272552.1:101..754"
                     /db_xref="GeneID:113109040"
ORIGIN      
        1 msdagseefd eeqgslgeye gdrneagerh gkgravlpkg dtyqgayetg krcgqgtykf
       61 kkgaryigew ymnlkhgegv fyypdgskye gswvddqrqg hgvytypngd tydgewlhhq
      121 rhgqgtythh etgsqymgtw vmgkmastgq lihlnhryqg nfvnnnpsgp gkyvfdigce
      181 qhgeyfqlep dreaeedetl ittflkwkpk avtglsv
//
LOCUS       XP_026128338             297 aa            linear   VRT 18-JUN-2025
DEFINITION  syntaxin-19 [Carassius auratus].
ACCESSION   XP_026128338
VERSION     XP_026128338.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272553.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..297
                     /product="syntaxin-19"
                     /calculated_mol_wt=34787
     Region          55..249
                     /region_name="Syntaxin"
                     /note="pfam00804"
                     /db_xref="CDD:459942"
     Region          217..283
                     /region_name="SNARE"
                     /note="SNARE motif; cl22856"
                     /db_xref="CDD:473982"
     Site            order(245,252,255)
                     /site_type="other"
                     /note="flanking leucine-zipper layers"
                     /db_xref="CDD:277192"
     Site            248
                     /site_type="active"
                     /note="zero layer [active]"
                     /db_xref="CDD:277192"
     CDS             1..297
                     /gene="stx19"
                     /coded_by="XM_026272553.1:366..1259"
                     /db_xref="GeneID:113109041"
ORIGIN      
        1 mkdrmeelrq rmkasdkpvd nnpfneeeee edmdpsslig lqavifetep vleiflkeaq
       61 sirdsieeln sevskfsqqq snfvatirrl simkkessmt rdikllaesl hkrldmlskq
      121 akqtedelgp dvatsriqka qhaalfrqfq qvmrqhndsi lskqnkckqf iirqlevsgr
      181 evsedevdnm ieqgkweifn eniivdakit rtqlseieqr hkellnlesn mkdlrdlfle
      241 vfmlveeqgh qieniqanve ktqdyvavtk ekfkmaaryk kknplrrlcc cccpwfr
//
LOCUS       XP_026128339             981 aa            linear   VRT 18-JUN-2025
DEFINITION  ephrin type-A receptor 3 isoform X1 [Carassius auratus].
ACCESSION   XP_026128339
VERSION     XP_026128339.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272554.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..981
                     /product="ephrin type-A receptor 3 isoform X1"
                     /calculated_mol_wt=109574
     Region          28..199
                     /region_name="EphR_LBD_A3"
                     /note="Ligand Binding Domain of Ephrin type-A Receptor 3;
                     cd10481"
                     /db_xref="CDD:198449"
     Site            order(52,54..58,65..66,68,70,101,103,108..109,150,
                     154..155,158..160,187..189,191)
                     /site_type="other"
                     /note="ephrin binding site [polypeptide binding]"
                     /db_xref="CDD:198449"
     Region          <323..>551
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain [General function
                     prediction only]; COG3401"
                     /db_xref="CDD:442628"
     Region          435..526
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(435,499,514)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(515..516,518..519)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          543..616
                     /region_name="EphA2_TM"
                     /note="Ephrin type-A receptor 2 transmembrane domain;
                     pfam14575"
                     /db_xref="CDD:464211"
     Region          614..880
                     /region_name="PTKc_EphR_A"
                     /note="Catalytic domain of the Protein Tyrosine Kinases,
                     Class EphA Ephrin Receptors; cd05066"
                     /db_xref="CDD:270651"
     Site            order(625,627..629,633,649,651,697..698,700,744,748..749,
                     751,762,781..785,794,828)
                     /site_type="active"
                     /db_xref="CDD:270651"
     Site            order(625..629,633,649,651,697..700,703..704,748..749,751,
                     762)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270651"
     Site            order(744,748,781..785,794,828)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270651"
     Site            761..787
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270651"
     Region          910..972
                     /region_name="SAM_superfamily"
                     /note="SAM (Sterile alpha motif); cl15755"
                     /db_xref="CDD:472832"
     CDS             1..981
                     /gene="epha3"
                     /coded_by="XM_026272554.1:119..3064"
                     /db_xref="GeneID:113109042"
ORIGIN      
        1 mdsktlilfl flftyissae fiihpsnevn llnskasqge lgwisspshg weeisgvdeh
       61 ytpirtfqvc nvmeysqnnw lrtnwiprns aqkiyvelkf tlrdcnsipm vltcketfnl
      121 hyletdedqg skfrehqfsk idtiaadesf tqmdlgdril klntevrevg pmtkkgfyla
      181 fqdvgacval vsvrvyfkkc pftvrnlamf pdtvptdsqs lvevrgscvn hsreedppkm
      241 ycstegewlv pigkclcnig yeewgvacqa crpgfykass gnvkcskcpp hsythqegat
      301 hcdceknyfr agedpvsmac srppsaprnv isainetsvi ldwtlpadsg grkdvifnvv
      361 ckrcwpgprq cepcrgavrf lpratgltnt tvtvvdllah tnytfeieaq ngvsslaptv
      421 rqyaaviitt nqaapsavtv irkdrtsrns islswmeper pngiildyev kyyekqeqet
      481 sytilrskgt nvtlnglkpd tiyllqirar taagyggssr kfefetspds fsissensqv
      541 vliavssava iilltvvlyi visrfcrysk skhpdekrlp fgnghlrlpg iktyvdphty
      601 edpsqavhef akeleascia idkvvgagef gevcsgrlkl pskkeicvai ktlkagytek
      661 qrrgflseas imgqfdhpni irlegvvtrs kpvmivteym engsldgflr khdaqftviq
      721 lvgmlrgias gmkylsdmgy vhrdlaarni lvnsnlvckv sdfglsrvle ddpeaayttr
      781 ggkipirwta peaiayrkft sasdvwsygi vlwevmsyge rpywemsnqd vikavdegyr
      841 lpppmecpat lyqlmldcwq kdrnnrpkfe qivsildkli rnpsslkita sttsrpvnll
      901 ldrtstdits fntmgdwles artlpckdaf sgvsysscdt laktsaedfk kvgvtivgpq
      961 kkivsslttl ethskngpvp v
//
LOCUS       XP_026128341             971 aa            linear   VRT 18-JUN-2025
DEFINITION  ephrin type-A receptor 3 isoform X2 [Carassius auratus].
ACCESSION   XP_026128341
VERSION     XP_026128341.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272556.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..971
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..971
                     /product="ephrin type-A receptor 3 isoform X2"
                     /calculated_mol_wt=108588
     Region          28..199
                     /region_name="EphR_LBD_A3"
                     /note="Ligand Binding Domain of Ephrin type-A Receptor 3;
                     cd10481"
                     /db_xref="CDD:198449"
     Site            order(52,54..58,65..66,68,70,101,103,108..109,150,
                     154..155,158..160,187..189,191)
                     /site_type="other"
                     /note="ephrin binding site [polypeptide binding]"
                     /db_xref="CDD:198449"
     Region          <323..>551
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain [General function
                     prediction only]; COG3401"
                     /db_xref="CDD:442628"
     Region          435..526
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(435,499,514)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(515..516,518..519)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          543..616
                     /region_name="EphA2_TM"
                     /note="Ephrin type-A receptor 2 transmembrane domain;
                     pfam14575"
                     /db_xref="CDD:464211"
     Region          614..880
                     /region_name="PTKc_EphR_A"
                     /note="Catalytic domain of the Protein Tyrosine Kinases,
                     Class EphA Ephrin Receptors; cd05066"
                     /db_xref="CDD:270651"
     Site            order(625,627..629,633,649,651,697..698,700,744,748..749,
                     751,762,781..785,794,828)
                     /site_type="active"
                     /db_xref="CDD:270651"
     Site            order(625..629,633,649,651,697..700,703..704,748..749,751,
                     762)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270651"
     Site            order(744,748,781..785,794,828)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270651"
     Site            761..787
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270651"
     Region          910..>947
                     /region_name="SAM_superfamily"
                     /note="SAM (Sterile alpha motif); cl15755"
                     /db_xref="CDD:472832"
     CDS             1..971
                     /gene="epha3"
                     /coded_by="XM_026272556.1:118..3033"
                     /db_xref="GeneID:113109042"
ORIGIN      
        1 mdsktlilfl flftyissae fiihpsnevn llnskasqge lgwisspshg weeisgvdeh
       61 ytpirtfqvc nvmeysqnnw lrtnwiprns aqkiyvelkf tlrdcnsipm vltcketfnl
      121 hyletdedqg skfrehqfsk idtiaadesf tqmdlgdril klntevrevg pmtkkgfyla
      181 fqdvgacval vsvrvyfkkc pftvrnlamf pdtvptdsqs lvevrgscvn hsreedppkm
      241 ycstegewlv pigkclcnig yeewgvacqa crpgfykass gnvkcskcpp hsythqegat
      301 hcdceknyfr agedpvsmac srppsaprnv isainetsvi ldwtlpadsg grkdvifnvv
      361 ckrcwpgprq cepcrgavrf lpratgltnt tvtvvdllah tnytfeieaq ngvsslaptv
      421 rqyaaviitt nqaapsavtv irkdrtsrns islswmeper pngiildyev kyyekqeqet
      481 sytilrskgt nvtlnglkpd tiyllqirar taagyggssr kfefetspds fsissensqv
      541 vliavssava iilltvvlyi visrfcrysk skhpdekrlp fgnghlrlpg iktyvdphty
      601 edpsqavhef akeleascia idkvvgagef gevcsgrlkl pskkeicvai ktlkagytek
      661 qrrgflseas imgqfdhpni irlegvvtrs kpvmivteym engsldgflr khdaqftviq
      721 lvgmlrgias gmkylsdmgy vhrdlaarni lvnsnlvckv sdfglsrvle ddpeaayttr
      781 ggkipirwta peaiayrkft sasdvwsygi vlwevmsyge rpywemsnqd vikavdegyr
      841 lpppmecpat lyqlmldcwq kdrnnrpkfe qivsildkli rnpsslkita sttsrpvnll
      901 ldrtstdits fntmgdwles artlpckdaf sgvsysscdt laktsaeicl tevrpaatcp
      961 ewepsmgitt l
//
LOCUS       XP_026128342             285 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein C3orf38 homolog [Carassius auratus].
ACCESSION   XP_026128342
VERSION     XP_026128342.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272557.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..285
                     /product="uncharacterized protein C3orf38 homolog"
                     /calculated_mol_wt=31825
     Region          4..262
                     /region_name="DUF4518"
                     /note="Domain of unknown function (DUF4518); pfam15008"
                     /db_xref="CDD:464440"
     CDS             1..285
                     /gene="c9h3orf38"
                     /coded_by="XM_026272557.1:102..959"
                     /db_xref="GeneID:113109043"
ORIGIN      
        1 maklsmkeqs gcrkllrllp lddlfalket vtnrliaves tqeaieaiit ysqdaeellk
       61 rkkvhrdvif kylasegvam ppnsdkqqli rrtteywssg eiserekntv vsedvgdgla
      121 dlpalgkqfc qwfftllnsq nptqgqpaqd wgpqhfwpdv rlrllsssge rcvdefngae
      181 lvsqrlhafa gqegllfcpn legqglkcvs sahglvlvav agtvhrdnac lgifekvfgl
      241 irspmdnnrw kikfvnmkve aqsaitdrql pvitydskel lslcd
//
LOCUS       XP_026128343            1167 aa            linear   VRT 18-JUN-2025
DEFINITION  unconventional myosin-Ib isoform X1 [Carassius auratus].
ACCESSION   XP_026128343
VERSION     XP_026128343.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272558.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1167
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1167
                     /product="unconventional myosin-Ib isoform X1"
                     /calculated_mol_wt=134728
     Region          26..687
                     /region_name="MYSc_Myo1"
                     /note="class I myosin, motor domain; cd01378"
                     /db_xref="CDD:276829"
     Site            order(53..56,61,105..112,152..162,384..389)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276829"
     Site            order(53..56,61)
                     /site_type="other"
                     /note="purine-binding loop"
                     /db_xref="CDD:276829"
     Site            105..112
                     /site_type="other"
                     /note="P-loop"
                     /db_xref="CDD:276829"
     Site            152..162
                     /site_type="other"
                     /note="switch I region"
                     /db_xref="CDD:276829"
     Site            384..389
                     /site_type="other"
                     /note="switch II region"
                     /db_xref="CDD:276829"
     Site            order(415..426,429..436,438)
                     /site_type="other"
                     /note="relay loop"
                     /db_xref="CDD:276829"
     Site            619..629
                     /site_type="other"
                     /note="SH1 helix"
                     /db_xref="CDD:276829"
     Site            order(631..657,674..687)
                     /site_type="other"
                     /note="converter subdomain"
                     /db_xref="CDD:276829"
     Region          969..1164
                     /region_name="Myosin_TH1"
                     /note="Unconventional myosin tail, actin- and
                     lipid-binding; pfam06017"
                     /db_xref="CDD:461801"
     CDS             1..1167
                     /gene="myo1b"
                     /coded_by="XM_026272558.1:233..3736"
                     /db_xref="GeneID:113109044"
ORIGIN      
        1 mevktslldn migvgdmvli eplsedtfie nlrkrfdhne iytyigsvvi smnpykslpi
       61 ytaekveeyr nrnfyelsph iyaladeayr slrdqdkdqc ilitgesgag kteaskfvms
      121 yvaavcgkgq evnkvkeqll qsnpvleafg naktvrndns srfgkymdie fdfkgdplgg
      181 visnylleks rvvkqprger nfhifyqlls gasddtlqkl kldrdfskyn ylsldsatvn
      241 glddaasfrt vrnamqivgf medevqsvle lvaavlklgn lefkpesrcn gfdesrikdk
      301 ndlkemcell gieqsvlera fsyrtveakm ekvsttlnva qayyardala knlysrlfsw
      361 lvnrinesik aqtksrkkvm gvldiygfei fengdnsfeq fiinycnekl qqifieltlh
      421 eeqeeyireg iewtnieyfn naiicdlien nkngilamld eeclrpgtvt detfldklnt
      481 vcaehqhfes rqsknskflt dhslphncfr iqhyagkvly rvegfvdknn dllyrdlsqa
      541 mykanqslik ilfpegnpak vnlkrpptag fqfrasvgtl mknlltknpn yircikpndk
      601 kaahiftdsl vchqvrylgl menvrvrrag yafrqayepc lerykmlckq twphwkgpar
      661 egvevllknl qvpaeefayg rskifirnpr tlffleekrr qcledlatli qkiyrgwksr
      721 thflllkksq vvvaawyrrf aqqkkyqnir ssalvvqsfi rgwkarkllr elkhkkrcee
      781 avttisaywh gtqarwelrr lkeearnkha vsviwaawlg tkarrelrrl khearskqav
      841 sviwacwqgt karrelkrlk eearrkhava viwaywlglk vrrdyrkffr anagkkiydf
      901 tiqrimqkyf mglkktmpsm spvdkswpar pygfldgthq elrrvfhlwr ckkyrsqfte
      961 ekkatyeekl aaselfkdkk alypssvgqp fkgdyveitk npkyqklnsl vedkvlladv
     1021 vskinrangk gapriflltk kslvladqkt gqvkasvpll dlssvsvstq sdgffalklk
     1081 egstsaakgd fllssdrlie iitklhriga tsadrnqini disdeflvqf kqdkvcvkfi
     1141 qgtpkngngv ackrknnrll evsvpsp
//
LOCUS       XP_026128344            1165 aa            linear   VRT 18-JUN-2025
DEFINITION  unconventional myosin-Ib isoform X2 [Carassius auratus].
ACCESSION   XP_026128344
VERSION     XP_026128344.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272559.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1165
                     /product="unconventional myosin-Ib isoform X2"
                     /calculated_mol_wt=134557
     Region          26..685
                     /region_name="MYSc_Myo1"
                     /note="class I myosin, motor domain; cd01378"
                     /db_xref="CDD:276829"
     Site            order(53..56,61,105..112,152..162,384..389)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276829"
     Site            order(53..56,61)
                     /site_type="other"
                     /note="purine-binding loop"
                     /db_xref="CDD:276829"
     Site            105..112
                     /site_type="other"
                     /note="P-loop"
                     /db_xref="CDD:276829"
     Site            152..162
                     /site_type="other"
                     /note="switch I region"
                     /db_xref="CDD:276829"
     Site            384..389
                     /site_type="other"
                     /note="switch II region"
                     /db_xref="CDD:276829"
     Site            order(413..424,427..434,436)
                     /site_type="other"
                     /note="relay loop"
                     /db_xref="CDD:276829"
     Site            617..627
                     /site_type="other"
                     /note="SH1 helix"
                     /db_xref="CDD:276829"
     Site            order(629..655,672..685)
                     /site_type="other"
                     /note="converter subdomain"
                     /db_xref="CDD:276829"
     Region          967..1162
                     /region_name="Myosin_TH1"
                     /note="Unconventional myosin tail, actin- and
                     lipid-binding; pfam06017"
                     /db_xref="CDD:461801"
     CDS             1..1165
                     /gene="myo1b"
                     /coded_by="XM_026272559.1:233..3730"
                     /db_xref="GeneID:113109044"
ORIGIN      
        1 mevktslldn migvgdmvli eplsedtfie nlrkrfdhne iytyigsvvi smnpykslpi
       61 ytaekveeyr nrnfyelsph iyaladeayr slrdqdkdqc ilitgesgag kteaskfvms
      121 yvaavcgkgq evnkvkeqll qsnpvleafg naktvrndns srfgkymdie fdfkgdplgg
      181 visnylleks rvvkqprger nfhifyqlls gasddtlqkl kldrdfskyn ylsldsatvn
      241 glddaasfrt vrnamqivgf medevqsvle lvaavlklgn lefkpesrcn gfdesrikdk
      301 ndlkemcell gieqsvlera fsyrtveakm ekvsttlnva qayyardala knlysrlfsw
      361 lvnrinesik aqtksrkkvm gvldiygfei fednsfeqfi inycneklqq ifieltlhee
      421 qeeyiregie wtnieyfnna iicdliennk ngilamldee clrpgtvtde tfldklntvc
      481 aehqhfesrq sknskfltdh slphncfriq hyagkvlyrv egfvdknndl lyrdlsqamy
      541 kanqslikil fpegnpakvn lkrpptagfq frasvgtlmk nlltknpnyi rcikpndkka
      601 ahiftdslvc hqvrylglme nvrvrragya frqayepcle rykmlckqtw phwkgpareg
      661 vevllknlqv paeefaygrs kifirnprtl ffleekrrqc ledlatliqk iyrgwksrth
      721 flllkksqvv vaawyrrfaq qkkyqnirss alvvqsfirg wkarkllrel khkkrceeav
      781 ttisaywhgt qarwelrrlk eearnkhavs viwaawlgtk arrelrrlkh earskqavsv
      841 iwacwqgtka rrelkrlkee arrkhavavi waywlglkvr rdyrkffran agkkiydfti
      901 qrimqkyfmg lkktmpsmsp vdkswparpy gfldgthqel rrvfhlwrck kyrsqfteek
      961 katyeeklaa selfkdkkal ypssvgqpfk gdyveitknp kyqklnslve dkvlladvvs
     1021 kinrangkga priflltkks lvladqktgq vkasvplldl ssvsvstqsd gffalklkeg
     1081 stsaakgdfl lssdrlieii tklhrigats adrnqinidi sdeflvqfkq dkvcvkfiqg
     1141 tpkngngvac krknnrllev svpsp
//
LOCUS       XP_026128345            1138 aa            linear   VRT 18-JUN-2025
DEFINITION  unconventional myosin-Ib isoform X3 [Carassius auratus].
ACCESSION   XP_026128345
VERSION     XP_026128345.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272560.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1138
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1138
                     /product="unconventional myosin-Ib isoform X3"
                     /calculated_mol_wt=131281
     Region          26..687
                     /region_name="MYSc_Myo1"
                     /note="class I myosin, motor domain; cd01378"
                     /db_xref="CDD:276829"
     Site            order(53..56,61,105..112,152..162,384..389)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276829"
     Site            order(53..56,61)
                     /site_type="other"
                     /note="purine-binding loop"
                     /db_xref="CDD:276829"
     Site            105..112
                     /site_type="other"
                     /note="P-loop"
                     /db_xref="CDD:276829"
     Site            152..162
                     /site_type="other"
                     /note="switch I region"
                     /db_xref="CDD:276829"
     Site            384..389
                     /site_type="other"
                     /note="switch II region"
                     /db_xref="CDD:276829"
     Site            order(415..426,429..436,438)
                     /site_type="other"
                     /note="relay loop"
                     /db_xref="CDD:276829"
     Site            619..629
                     /site_type="other"
                     /note="SH1 helix"
                     /db_xref="CDD:276829"
     Site            order(631..657,674..687)
                     /site_type="other"
                     /note="converter subdomain"
                     /db_xref="CDD:276829"
     Region          940..1135
                     /region_name="Myosin_TH1"
                     /note="Unconventional myosin tail, actin- and
                     lipid-binding; pfam06017"
                     /db_xref="CDD:461801"
     CDS             1..1138
                     /gene="myo1b"
                     /coded_by="XM_026272560.1:232..3648"
                     /db_xref="GeneID:113109044"
ORIGIN      
        1 mevktslldn migvgdmvli eplsedtfie nlrkrfdhne iytyigsvvi smnpykslpi
       61 ytaekveeyr nrnfyelsph iyaladeayr slrdqdkdqc ilitgesgag kteaskfvms
      121 yvaavcgkgq evnkvkeqll qsnpvleafg naktvrndns srfgkymdie fdfkgdplgg
      181 visnylleks rvvkqprger nfhifyqlls gasddtlqkl kldrdfskyn ylsldsatvn
      241 glddaasfrt vrnamqivgf medevqsvle lvaavlklgn lefkpesrcn gfdesrikdk
      301 ndlkemcell gieqsvlera fsyrtveakm ekvsttlnva qayyardala knlysrlfsw
      361 lvnrinesik aqtksrkkvm gvldiygfei fengdnsfeq fiinycnekl qqifieltlh
      421 eeqeeyireg iewtnieyfn naiicdlien nkngilamld eeclrpgtvt detfldklnt
      481 vcaehqhfes rqsknskflt dhslphncfr iqhyagkvly rvegfvdknn dllyrdlsqa
      541 mykanqslik ilfpegnpak vnlkrpptag fqfrasvgtl mknlltknpn yircikpndk
      601 kaahiftdsl vchqvrylgl menvrvrrag yafrqayepc lerykmlckq twphwkgpar
      661 egvevllknl qvpaeefayg rskifirnpr tlffleekrr qcledlatli qkiyrgwksr
      721 thflllkksq vvvaawyrrf aqqkkyqnir ssalvvqsfi rgwkarkllr elkhkkrcee
      781 avttisaywh gtqarwelrr lkeearnkha vsviwaawlg tkarrelkrl keearrkhav
      841 aviwaywlgl kvrrdyrkff ranagkkiyd ftiqrimqky fmglkktmps mspvdkswpa
      901 rpygfldgth qelrrvfhlw rckkyrsqft eekkatyeek laaselfkdk kalypssvgq
      961 pfkgdyveit knpkyqklns lvedkvllad vvskinrang kgaprifllt kkslvladqk
     1021 tgqvkasvpl ldlssvsvst qsdgffalkl kegstsaakg dfllssdrli eiitklhrig
     1081 atsadrnqin idisdeflvq fkqdkvcvkf iqgtpkngng vackrknnrl levsvpsp
//
LOCUS       XP_026128346            1109 aa            linear   VRT 18-JUN-2025
DEFINITION  unconventional myosin-Ib isoform X4 [Carassius auratus].
ACCESSION   XP_026128346
VERSION     XP_026128346.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272561.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1109
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1109
                     /product="unconventional myosin-Ib isoform X4"
                     /calculated_mol_wt=127823
     Region          26..687
                     /region_name="MYSc_Myo1"
                     /note="class I myosin, motor domain; cd01378"
                     /db_xref="CDD:276829"
     Site            order(53..56,61,105..112,152..162,384..389)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276829"
     Site            order(53..56,61)
                     /site_type="other"
                     /note="purine-binding loop"
                     /db_xref="CDD:276829"
     Site            105..112
                     /site_type="other"
                     /note="P-loop"
                     /db_xref="CDD:276829"
     Site            152..162
                     /site_type="other"
                     /note="switch I region"
                     /db_xref="CDD:276829"
     Site            384..389
                     /site_type="other"
                     /note="switch II region"
                     /db_xref="CDD:276829"
     Site            order(415..426,429..436,438)
                     /site_type="other"
                     /note="relay loop"
                     /db_xref="CDD:276829"
     Site            619..629
                     /site_type="other"
                     /note="SH1 helix"
                     /db_xref="CDD:276829"
     Site            order(631..657,674..687)
                     /site_type="other"
                     /note="converter subdomain"
                     /db_xref="CDD:276829"
     Region          911..1106
                     /region_name="Myosin_TH1"
                     /note="Unconventional myosin tail, actin- and
                     lipid-binding; pfam06017"
                     /db_xref="CDD:461801"
     CDS             1..1109
                     /gene="myo1b"
                     /coded_by="XM_026272561.1:232..3561"
                     /db_xref="GeneID:113109044"
ORIGIN      
        1 mevktslldn migvgdmvli eplsedtfie nlrkrfdhne iytyigsvvi smnpykslpi
       61 ytaekveeyr nrnfyelsph iyaladeayr slrdqdkdqc ilitgesgag kteaskfvms
      121 yvaavcgkgq evnkvkeqll qsnpvleafg naktvrndns srfgkymdie fdfkgdplgg
      181 visnylleks rvvkqprger nfhifyqlls gasddtlqkl kldrdfskyn ylsldsatvn
      241 glddaasfrt vrnamqivgf medevqsvle lvaavlklgn lefkpesrcn gfdesrikdk
      301 ndlkemcell gieqsvlera fsyrtveakm ekvsttlnva qayyardala knlysrlfsw
      361 lvnrinesik aqtksrkkvm gvldiygfei fengdnsfeq fiinycnekl qqifieltlh
      421 eeqeeyireg iewtnieyfn naiicdlien nkngilamld eeclrpgtvt detfldklnt
      481 vcaehqhfes rqsknskflt dhslphncfr iqhyagkvly rvegfvdknn dllyrdlsqa
      541 mykanqslik ilfpegnpak vnlkrpptag fqfrasvgtl mknlltknpn yircikpndk
      601 kaahiftdsl vchqvrylgl menvrvrrag yafrqayepc lerykmlckq twphwkgpar
      661 egvevllknl qvpaeefayg rskifirnpr tlffleekrr qcledlatli qkiyrgwksr
      721 thflllkksq vvvaawyrrf aqqkkyqnir ssalvvqsfi rgwkarkllr elkhkkrcee
      781 avttisaywh gtqarrelkr lkeearrkha vaviwaywlg lkvrrdyrkf franagkkiy
      841 dftiqrimqk yfmglkktmp smspvdkswp arpygfldgt hqelrrvfhl wrckkyrsqf
      901 teekkatyee klaaselfkd kkalypssvg qpfkgdyvei tknpkyqkln slvedkvlla
      961 dvvskinran gkgaprifll tkkslvladq ktgqvkasvp lldlssvsvs tqsdgffalk
     1021 lkegstsaak gdfllssdrl ieiitklhri gatsadrnqi nidisdeflv qfkqdkvcvk
     1081 fiqgtpkngn gvackrknnr llevsvpsp
//
LOCUS       XP_026128347            1107 aa            linear   VRT 18-JUN-2025
DEFINITION  unconventional myosin-Ib isoform X5 [Carassius auratus].
ACCESSION   XP_026128347
VERSION     XP_026128347.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272562.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1107
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1107
                     /product="unconventional myosin-Ib isoform X5"
                     /calculated_mol_wt=127652
     Region          26..685
                     /region_name="MYSc_Myo1"
                     /note="class I myosin, motor domain; cd01378"
                     /db_xref="CDD:276829"
     Site            order(53..56,61,105..112,152..162,384..389)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276829"
     Site            order(53..56,61)
                     /site_type="other"
                     /note="purine-binding loop"
                     /db_xref="CDD:276829"
     Site            105..112
                     /site_type="other"
                     /note="P-loop"
                     /db_xref="CDD:276829"
     Site            152..162
                     /site_type="other"
                     /note="switch I region"
                     /db_xref="CDD:276829"
     Site            384..389
                     /site_type="other"
                     /note="switch II region"
                     /db_xref="CDD:276829"
     Site            order(413..424,427..434,436)
                     /site_type="other"
                     /note="relay loop"
                     /db_xref="CDD:276829"
     Site            617..627
                     /site_type="other"
                     /note="SH1 helix"
                     /db_xref="CDD:276829"
     Site            order(629..655,672..685)
                     /site_type="other"
                     /note="converter subdomain"
                     /db_xref="CDD:276829"
     Region          909..1104
                     /region_name="Myosin_TH1"
                     /note="Unconventional myosin tail, actin- and
                     lipid-binding; pfam06017"
                     /db_xref="CDD:461801"
     CDS             1..1107
                     /gene="myo1b"
                     /coded_by="XM_026272562.1:232..3555"
                     /db_xref="GeneID:113109044"
ORIGIN      
        1 mevktslldn migvgdmvli eplsedtfie nlrkrfdhne iytyigsvvi smnpykslpi
       61 ytaekveeyr nrnfyelsph iyaladeayr slrdqdkdqc ilitgesgag kteaskfvms
      121 yvaavcgkgq evnkvkeqll qsnpvleafg naktvrndns srfgkymdie fdfkgdplgg
      181 visnylleks rvvkqprger nfhifyqlls gasddtlqkl kldrdfskyn ylsldsatvn
      241 glddaasfrt vrnamqivgf medevqsvle lvaavlklgn lefkpesrcn gfdesrikdk
      301 ndlkemcell gieqsvlera fsyrtveakm ekvsttlnva qayyardala knlysrlfsw
      361 lvnrinesik aqtksrkkvm gvldiygfei fednsfeqfi inycneklqq ifieltlhee
      421 qeeyiregie wtnieyfnna iicdliennk ngilamldee clrpgtvtde tfldklntvc
      481 aehqhfesrq sknskfltdh slphncfriq hyagkvlyrv egfvdknndl lyrdlsqamy
      541 kanqslikil fpegnpakvn lkrpptagfq frasvgtlmk nlltknpnyi rcikpndkka
      601 ahiftdslvc hqvrylglme nvrvrragya frqayepcle rykmlckqtw phwkgpareg
      661 vevllknlqv paeefaygrs kifirnprtl ffleekrrqc ledlatliqk iyrgwksrth
      721 flllkksqvv vaawyrrfaq qkkyqnirss alvvqsfirg wkarkllrel khkkrceeav
      781 ttisaywhgt qarrelkrlk eearrkhava viwaywlglk vrrdyrkffr anagkkiydf
      841 tiqrimqkyf mglkktmpsm spvdkswpar pygfldgthq elrrvfhlwr ckkyrsqfte
      901 ekkatyeekl aaselfkdkk alypssvgqp fkgdyveitk npkyqklnsl vedkvlladv
      961 vskinrangk gapriflltk kslvladqkt gqvkasvpll dlssvsvstq sdgffalklk
     1021 egstsaakgd fllssdrlie iitklhriga tsadrnqini disdeflvqf kqdkvcvkfi
     1081 qgtpkngngv ackrknnrll evsvpsp
//
LOCUS       XP_026128348            1080 aa            linear   VRT 18-JUN-2025
DEFINITION  unconventional myosin-Ib isoform X6 [Carassius auratus].
ACCESSION   XP_026128348
VERSION     XP_026128348.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272563.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1080
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1080
                     /product="unconventional myosin-Ib isoform X6"
                     /calculated_mol_wt=124292
     Region          26..687
                     /region_name="MYSc_Myo1"
                     /note="class I myosin, motor domain; cd01378"
                     /db_xref="CDD:276829"
     Site            order(53..56,61,105..112,152..162,384..389)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276829"
     Site            order(53..56,61)
                     /site_type="other"
                     /note="purine-binding loop"
                     /db_xref="CDD:276829"
     Site            105..112
                     /site_type="other"
                     /note="P-loop"
                     /db_xref="CDD:276829"
     Site            152..162
                     /site_type="other"
                     /note="switch I region"
                     /db_xref="CDD:276829"
     Site            384..389
                     /site_type="other"
                     /note="switch II region"
                     /db_xref="CDD:276829"
     Site            order(415..426,429..436,438)
                     /site_type="other"
                     /note="relay loop"
                     /db_xref="CDD:276829"
     Site            619..629
                     /site_type="other"
                     /note="SH1 helix"
                     /db_xref="CDD:276829"
     Site            order(631..657,674..687)
                     /site_type="other"
                     /note="converter subdomain"
                     /db_xref="CDD:276829"
     Region          882..1077
                     /region_name="Myosin_TH1"
                     /note="Unconventional myosin tail, actin- and
                     lipid-binding; pfam06017"
                     /db_xref="CDD:461801"
     CDS             1..1080
                     /gene="myo1b"
                     /coded_by="XM_026272563.1:232..3474"
                     /db_xref="GeneID:113109044"
ORIGIN      
        1 mevktslldn migvgdmvli eplsedtfie nlrkrfdhne iytyigsvvi smnpykslpi
       61 ytaekveeyr nrnfyelsph iyaladeayr slrdqdkdqc ilitgesgag kteaskfvms
      121 yvaavcgkgq evnkvkeqll qsnpvleafg naktvrndns srfgkymdie fdfkgdplgg
      181 visnylleks rvvkqprger nfhifyqlls gasddtlqkl kldrdfskyn ylsldsatvn
      241 glddaasfrt vrnamqivgf medevqsvle lvaavlklgn lefkpesrcn gfdesrikdk
      301 ndlkemcell gieqsvlera fsyrtveakm ekvsttlnva qayyardala knlysrlfsw
      361 lvnrinesik aqtksrkkvm gvldiygfei fengdnsfeq fiinycnekl qqifieltlh
      421 eeqeeyireg iewtnieyfn naiicdlien nkngilamld eeclrpgtvt detfldklnt
      481 vcaehqhfes rqsknskflt dhslphncfr iqhyagkvly rvegfvdknn dllyrdlsqa
      541 mykanqslik ilfpegnpak vnlkrpptag fqfrasvgtl mknlltknpn yircikpndk
      601 kaahiftdsl vchqvrylgl menvrvrrag yafrqayepc lerykmlckq twphwkgpar
      661 egvevllknl qvpaeefayg rskifirnpr tlffleekrr qcledlatli qkiyrgwksr
      721 thflllkksq vvvaawyrrf aqqkkyqnir ssalvvqsfi rgwkarkllr elkhkkrcee
      781 avttisaywh gtqvrrdyrk ffranagkki ydftiqrimq kyfmglkktm psmspvdksw
      841 parpygfldg thqelrrvfh lwrckkyrsq fteekkatye eklaaselfk dkkalypssv
      901 gqpfkgdyve itknpkyqkl nslvedkvll advvskinra ngkgaprifl ltkkslvlad
      961 qktgqvkasv plldlssvsv stqsdgffal klkegstsaa kgdfllssdr lieiitklhr
     1021 igatsadrnq inidisdefl vqfkqdkvcv kfiqgtpkng ngvackrknn rllevsvpsp
//
LOCUS       XP_026128349            1136 aa            linear   VRT 18-JUN-2025
DEFINITION  unconventional myosin-Ib isoform X7 [Carassius auratus].
ACCESSION   XP_026128349
VERSION     XP_026128349.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272564.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1136
                     /product="unconventional myosin-Ib isoform X7"
                     /calculated_mol_wt=131110
     Region          26..685
                     /region_name="MYSc_Myo1"
                     /note="class I myosin, motor domain; cd01378"
                     /db_xref="CDD:276829"
     Site            order(53..56,61,105..112,152..162,384..389)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276829"
     Site            order(53..56,61)
                     /site_type="other"
                     /note="purine-binding loop"
                     /db_xref="CDD:276829"
     Site            105..112
                     /site_type="other"
                     /note="P-loop"
                     /db_xref="CDD:276829"
     Site            152..162
                     /site_type="other"
                     /note="switch I region"
                     /db_xref="CDD:276829"
     Site            384..389
                     /site_type="other"
                     /note="switch II region"
                     /db_xref="CDD:276829"
     Site            order(413..424,427..434,436)
                     /site_type="other"
                     /note="relay loop"
                     /db_xref="CDD:276829"
     Site            617..627
                     /site_type="other"
                     /note="SH1 helix"
                     /db_xref="CDD:276829"
     Site            order(629..655,672..685)
                     /site_type="other"
                     /note="converter subdomain"
                     /db_xref="CDD:276829"
     Region          938..1133
                     /region_name="Myosin_TH1"
                     /note="Unconventional myosin tail, actin- and
                     lipid-binding; pfam06017"
                     /db_xref="CDD:461801"
     CDS             1..1136
                     /gene="myo1b"
                     /coded_by="XM_026272564.1:10..3420"
                     /db_xref="GeneID:113109044"
ORIGIN      
        1 mevktslldn migvgdmvli eplsedtfie nlrkrfdhne iytyigsvvi smnpykslpi
       61 ytaekveeyr nrnfyelsph iyaladeayr slrdqdkdqc ilitgesgag kteaskfvms
      121 yvaavcgkgq evnkvkeqll qsnpvleafg naktvrndns srfgkymdie fdfkgdplgg
      181 visnylleks rvvkqprger nfhifyqlls gasddtlqkl kldrdfskyn ylsldsatvn
      241 glddaasfrt vrnamqivgf medevqsvle lvaavlklgn lefkpesrcn gfdesrikdk
      301 ndlkemcell gieqsvlera fsyrtveakm ekvsttlnva qayyardala knlysrlfsw
      361 lvnrinesik aqtksrkkvm gvldiygfei fednsfeqfi inycneklqq ifieltlhee
      421 qeeyiregie wtnieyfnna iicdliennk ngilamldee clrpgtvtde tfldklntvc
      481 aehqhfesrq sknskfltdh slphncfriq hyagkvlyrv egfvdknndl lyrdlsqamy
      541 kanqslikil fpegnpakvn lkrpptagfq frasvgtlmk nlltknpnyi rcikpndkka
      601 ahiftdslvc hqvrylglme nvrvrragya frqayepcle rykmlckqtw phwkgpareg
      661 vevllknlqv paeefaygrs kifirnprtl ffleekrrqc ledlatliqk iyrgwksrth
      721 flllkksqvv vaawyrrfaq qkkyqnirss alvvqsfirg wkarkllrel khkkrceeav
      781 ttisaywhgt qarwelrrlk eearnkhavs viwaawlgtk arrelkrlke earrkhavav
      841 iwaywlglkv rrdyrkffra nagkkiydft iqrimqkyfm glkktmpsms pvdkswparp
      901 ygfldgthqe lrrvfhlwrc kkyrsqftee kkatyeekla aselfkdkka lypssvgqpf
      961 kgdyveitkn pkyqklnslv edkvlladvv skinrangkg apriflltkk slvladqktg
     1021 qvkasvplld lssvsvstqs dgffalklke gstsaakgdf llssdrliei itklhrigat
     1081 sadrnqinid isdeflvqfk qdkvcvkfiq gtpkngngva ckrknnrlle vsvpsp
//
LOCUS       XP_026128350            1078 aa            linear   VRT 18-JUN-2025
DEFINITION  unconventional myosin-Ib isoform X8 [Carassius auratus].
ACCESSION   XP_026128350
VERSION     XP_026128350.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272565.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1078
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1078
                     /product="unconventional myosin-Ib isoform X8"
                     /calculated_mol_wt=124121
     Region          26..685
                     /region_name="MYSc_Myo1"
                     /note="class I myosin, motor domain; cd01378"
                     /db_xref="CDD:276829"
     Site            order(53..56,61,105..112,152..162,384..389)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276829"
     Site            order(53..56,61)
                     /site_type="other"
                     /note="purine-binding loop"
                     /db_xref="CDD:276829"
     Site            105..112
                     /site_type="other"
                     /note="P-loop"
                     /db_xref="CDD:276829"
     Site            152..162
                     /site_type="other"
                     /note="switch I region"
                     /db_xref="CDD:276829"
     Site            384..389
                     /site_type="other"
                     /note="switch II region"
                     /db_xref="CDD:276829"
     Site            order(413..424,427..434,436)
                     /site_type="other"
                     /note="relay loop"
                     /db_xref="CDD:276829"
     Site            617..627
                     /site_type="other"
                     /note="SH1 helix"
                     /db_xref="CDD:276829"
     Site            order(629..655,672..685)
                     /site_type="other"
                     /note="converter subdomain"
                     /db_xref="CDD:276829"
     Region          880..1075
                     /region_name="Myosin_TH1"
                     /note="Unconventional myosin tail, actin- and
                     lipid-binding; pfam06017"
                     /db_xref="CDD:461801"
     CDS             1..1078
                     /gene="myo1b"
                     /coded_by="XM_026272565.1:10..3246"
                     /db_xref="GeneID:113109044"
ORIGIN      
        1 mevktslldn migvgdmvli eplsedtfie nlrkrfdhne iytyigsvvi smnpykslpi
       61 ytaekveeyr nrnfyelsph iyaladeayr slrdqdkdqc ilitgesgag kteaskfvms
      121 yvaavcgkgq evnkvkeqll qsnpvleafg naktvrndns srfgkymdie fdfkgdplgg
      181 visnylleks rvvkqprger nfhifyqlls gasddtlqkl kldrdfskyn ylsldsatvn
      241 glddaasfrt vrnamqivgf medevqsvle lvaavlklgn lefkpesrcn gfdesrikdk
      301 ndlkemcell gieqsvlera fsyrtveakm ekvsttlnva qayyardala knlysrlfsw
      361 lvnrinesik aqtksrkkvm gvldiygfei fednsfeqfi inycneklqq ifieltlhee
      421 qeeyiregie wtnieyfnna iicdliennk ngilamldee clrpgtvtde tfldklntvc
      481 aehqhfesrq sknskfltdh slphncfriq hyagkvlyrv egfvdknndl lyrdlsqamy
      541 kanqslikil fpegnpakvn lkrpptagfq frasvgtlmk nlltknpnyi rcikpndkka
      601 ahiftdslvc hqvrylglme nvrvrragya frqayepcle rykmlckqtw phwkgpareg
      661 vevllknlqv paeefaygrs kifirnprtl ffleekrrqc ledlatliqk iyrgwksrth
      721 flllkksqvv vaawyrrfaq qkkyqnirss alvvqsfirg wkarkllrel khkkrceeav
      781 ttisaywhgt qvrrdyrkff ranagkkiyd ftiqrimqky fmglkktmps mspvdkswpa
      841 rpygfldgth qelrrvfhlw rckkyrsqft eekkatyeek laaselfkdk kalypssvgq
      901 pfkgdyveit knpkyqklns lvedkvllad vvskinrang kgaprifllt kkslvladqk
      961 tgqvkasvpl ldlssvsvst qsdgffalkl kegstsaakg dfllssdrli eiitklhrig
     1021 atsadrnqin idisdeflvq fkqdkvcvkf iqgtpkngng vackrknnrl levsvpsp
//
LOCUS       XP_026128351             585 aa            linear   VRT 18-JUN-2025
DEFINITION  NXPE family member 3-like [Carassius auratus].
ACCESSION   XP_026128351
VERSION     XP_026128351.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272566.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..585
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..585
                     /product="NXPE family member 3-like"
                     /calculated_mol_wt=67164
     Region          <152..302
                     /region_name="Neurexophilin"
                     /note="pfam06312"
                     /db_xref="CDD:428882"
     CDS             1..585
                     /gene="LOC113109046"
                     /coded_by="XM_026272566.1:107..1864"
                     /db_xref="GeneID:113109046"
ORIGIN      
        1 mpsknvmeie trkqhfhrer sclrrfftgl cllvimcflv vwsymgngrk khpqpnflsq
       61 hfaglsnspn stspsalssd esivssfyse fgislddyss lqqtvywaep drsitnlsms
      121 tspahttfii enlkesyqig eelfvvvhak dfdnkskhyg gdffqaklfw sktkasvfge
      181 vvdllngsys vrfllpwvge aqvavrlihs seavqvlkhh rdtdsdrvyf ngyyegpgpn
      241 ktrlseivkc nvkwdkngle rmgtrdccce yndprtretw rcqrpkslpc safvyhsmgg
      301 yrnrltnkek ilmtqtnkgi ngdksiikiv yfhgnktidv tekcrpglht pvpagfylnd
      361 vwtsfvcstr hfttqkttec lkskhiymmg dstmrqwfef fvkaiptlnq mnlhvqyqsg
      421 pliavdvknn idlhwrahnv plrtlktava nlhyisneid dlaggphtvi ifnlgphftt
      481 ypldfythrv lrirkavlal lkrapdttvv iktvntgykd ifgsdwyslq ldrilrwvfq
      541 dvgvyildvw qmtachykke nihpapviik neidillsft cpkli
//
LOCUS       XP_026128352             418 aa            linear   VRT 18-JUN-2025
DEFINITION  basic leucine zipper and W2 domain-containing protein 1-B
            [Carassius auratus].
ACCESSION   XP_026128352
VERSION     XP_026128352.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272567.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..418
                     /product="basic leucine zipper and W2 domain-containing
                     protein 1-B"
                     /calculated_mol_wt=47758
     Region          217..407
                     /region_name="W2_eIF5C_like"
                     /note="C-terminal W2 domain of the eukaryotic translation
                     initiation factor 5C and similar proteins; cd11560"
                     /db_xref="CDD:211398"
     CDS             1..418
                     /gene="LOC113109047"
                     /coded_by="XM_026272567.1:151..1407"
                     /db_xref="GeneID:113109047"
ORIGIN      
        1 msnqkqqkpt ltgqrfktrk rdekerfdpt qfqesivqgl nqtgadleav akfldssgak
       61 ldyrryaetl fdilvaggml apggalsddm trtnfclfta pedvktmkay aqvfnklirr
      121 ykylekgfee eikklllflk gfsesernkl amltgillan gspsasilgs lfndnlvkeg
      181 vspafavklf kawinekdin svaaslrkvg mdnrlmelfp vnkrsydhfs kyftdaglke
      241 lsdfarnqrs lgarkelqke lqeqmsqgvs fkeiivyvke emkksgiseq mvigimwtsv
      301 mssvewnkke elvteqaikh lkqyspllka fatqgqselt lllrvqeycy dnihfmkafq
      361 kivlllykvd vlseeavlkw yseahlakgk svfleqmkkf vewlknaeee seseeetd
//
LOCUS       XP_026128354            1465 aa            linear   VRT 18-JUN-2025
DEFINITION  LOW QUALITY PROTEIN: immunoglobulin superfamily member 3-like
            [Carassius auratus].
ACCESSION   XP_026128354
VERSION     XP_026128354.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272569.1
KEYWORDS    RefSeq; corrected model.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            frameshifts :: corrected 1 indel
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1465
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1465
                     /product="LOW QUALITY PROTEIN: immunoglobulin superfamily
                     member 3-like"
                     /calculated_mol_wt=165567
     Region          46..137
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          47..51
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          109..113
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          123..128
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          159..259
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          170..174
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..191
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          237..241
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          251..256
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          299..386
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          557..638
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          680..770
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          686..690
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          704..709
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          751..755
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          765..770
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          822..906
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          822..825
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          835..842
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          881..885
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          895..900
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..1465
                     /gene="LOC113109048"
                     /coded_by="XM_026272569.1:32..4429"
                     /note="The sequence of the model RefSeq protein was
                     modified relative to its source genomic sequence to
                     represent the inferred CDS: inserted 1 base in 1 codon"
                     /db_xref="GeneID:113109048"
ORIGIN      
        1 mvdfwcqkwk lplllcltgl lqwdlcsgqi qvqiqkgply rmkgypisis cnvtgftgps
       61 kqdfefilkk qnmelnmist sdpnfaygmf sdrirkkeiy ierlsgssvi lwikdlqend
      121 agdllcatlh tggeyfgdyg aesklnviad tleasysgsp sqslsegdpl qlecqvssqt
      181 cqhshlsvtw flhgeddenp wpiitldkdl tvkpgagfed ryraglismd kvedttyrlk
      241 mpqvqqsdqg kffckaiewi qdpdrswtqi ahkttkacdv eikriesnla vvmlmndavt
      301 egdalhvscs vsgfkgplsv swqhkkalga ffsdvvslth egvmkdvgar yqsrnvqtfh
      361 spagsftlql gassisdnge ykcivsewtv qsngemkait qsqqkaitvk sveslmavsl
      421 tsrttnlsid ssvqllcrvr gpkvslalrw mfqphnsaaq inilsishtg emewradqrn
      481 yqlniqaqpg dtcftlmvpr askqqegqyq cqvdayqkdv qkafknsnll avivhkpdsk
      541 msllsptsrl ettvdtdakl ecsvmkttti tsrftvtwmf gsqvlltmdl davvkfgpaa
      601 glemdqrirl eirqkqnfql tiqqvrtsds gqyhceveew lqdplgdwys lkkmsvstel
      661 vvkekasyfk mnkadtqlkv eegkqvklkc svegigsdpt lrysltwmfn qyqstssall
      721 tyshdgllky ksfdselvgr lhfstpevgv fhltihrsiq edrgryycev qqyqldckgq
      781 wsrkardksg ftnvtvqlie nklqvnkeex sltitnlqag ftidcviksr ssdkslfevt
      841 wsrglinerp viifnasrdg tlhsaiddke lvfgrpsamr fkltvpnvnp tdtglyhcqv
      901 vewiqtaank wrsigqdisg kisvhvdted qqknfsftmd kkdnnldike geqfdlecsl
      961 niekddpthh yslrwvfnrp gstsgialls yshdgrlqyh tenqdrlrfs rpnsdtfcla
     1021 vlnsdigdsg gyqcrveqyq hdcngqwkpm alaqsgtttv tvrsierklr vqkdnqmlni
     1081 tnhqtsftid cvidsqssdt svfevtwfkv qeegpltmfs arhdgtlhsa ipdknllfgr
     1141 plathykltv lqisptdigq yycqveewll tantwkklas dksgelsiyv hteesklsvq
     1201 knnrminitn dqtsftidcv idsqssdtsg fevtwfkvqe egpltmfsar hdgtlhsaip
     1261 dknllfgrpl akhykltvlq isptdigqyy cqveewllta ntwkklasdk sgelsiyvht
     1321 eesklhvqkn nrminitndq tsftidcvid sqssdtsgfe vtwfkvqeeg pltmfsarhd
     1381 gtlhsaipdk nllfgrplak hykltvlqis ptdigqyycq veewlltant wkklasdksg
     1441 elsiyvhteg nypecsmflk npcck
//
LOCUS       XP_026128355            1011 aa            linear   VRT 18-JUN-2025
DEFINITION  immunoglobulin superfamily member 2-like isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128355
VERSION     XP_026128355.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272570.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1011
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1011
                     /product="immunoglobulin superfamily member 2-like isoform
                     X1"
                     /calculated_mol_wt=114131
     Region          49..159
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          171..271
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          182..186
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          199..203
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          249..253
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          263..268
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          317..414
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          339..343
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          397..402
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          445..534
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          451..455
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          465..470
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          512..516
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          526..531
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          703..784
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     CDS             1..1011
                     /gene="LOC113109049"
                     /coded_by="XM_026272570.1:224..3259"
                     /db_xref="GeneID:113109049"
ORIGIN      
        1 mrekaegsis lrmmdlwcrl whlplmlyis gllqfdlcsg qiqvqiqegp lyrvkgypis
       61 iscnvtgftg pserdfdfil rkqnmeinii stskedfsyg mfsgrirkke iyivrlsgss
      121 vvlwikdlqe ndagdllcvt khtggpyygd yddeaklnvi adtleasysg spsqslsegd
      181 plqlecqvss qtfqhthlsv twflhgeede nprpiitldk dltvkpgagf edryraglis
      241 mdkvedttyr lkmpqvqqsd qgkffckaie wiqdpdrswt qiahktttac dveikrivvp
      301 dadsfsvnlk askgplqegd aldircsvna qnlpghffsv twlkdqqrva qigssgvltv
      361 fdsykdrena aemravktsh mdylltvrsa rtedhgqyqc evwqenmned gtfkkiqkqm
      421 sspetvsita kesnlavvml mkdavtegda lhvscsvsgf kgplsvswqh kkdpgasfsd
      481 vvslthegvm kdvgaryqsr nvqtfhspag nftlqlgasa vsdsgeykci vsewtvqsng
      541 emkaitqsqq kaitvksies lmvvsltsrt snvpidspvq llcrvrgprv slalrwmfqp
      601 hnstvqtnil sishtgemtw radqrnyqln iqarpedtrf tlmvpraskq qkgqyqcqvd
      661 ayqkdvqkaf knsnllaviv hkpdskmsll sptsrlettv dtdaklecsv mktttntsrf
      721 tvawmfgsqv lltmdldavv kfgpaaglem dqrirleirq kqnfqmtiqq vrtsdsgqyh
      781 ceveewlqdp lvdwyslkkm svstelvvke kesklhvqkd nrmlnvtnhq agftidcvid
      841 sqssdksvfe vtwfkvqkeg qvaiftarrd gilhsaiadr nlvfgrplat hykltvlqis
      901 ptdigqyycq veewlltsnt wkkfasdksg elsihvhteg ekqidpllit laiaiplicf
      961 lvlviifllr kshkkkyeis mkyelkkmkk kkkkkdclwa etnvlngpst n
//
LOCUS       XP_026128356             999 aa            linear   VRT 18-JUN-2025
DEFINITION  immunoglobulin superfamily member 2-like isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128356
VERSION     XP_026128356.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272571.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..999
                     /product="immunoglobulin superfamily member 2-like isoform
                     X2"
                     /calculated_mol_wt=112772
     Region          37..147
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          159..259
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          170..174
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..191
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          237..241
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          251..256
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          305..402
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          327..331
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          385..390
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          433..522
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          439..443
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          453..458
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          500..504
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          514..519
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          691..772
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     CDS             1..999
                     /gene="LOC113109049"
                     /coded_by="XM_026272571.1:43..3042"
                     /db_xref="GeneID:113109049"
ORIGIN      
        1 mmdlwcrlwh lplmlyisgl lqfdlcsgqi qvqiqegply rvkgypisis cnvtgftgps
       61 erdfdfilrk qnmeiniist skedfsygmf sgrirkkeiy ivrlsgssvv lwikdlqend
      121 agdllcvtkh tggpyygdyd deaklnviad tleasysgsp sqslsegdpl qlecqvssqt
      181 fqhthlsvtw flhgeedenp rpiitldkdl tvkpgagfed ryraglismd kvedttyrlk
      241 mpqvqqsdqg kffckaiewi qdpdrswtqi ahktttacdv eikrivvpda dsfsvnlkas
      301 kgplqegdal dircsvnaqn lpghffsvtw lkdqqrvaqi gssgvltvfd sykdrenaae
      361 mravktshmd ylltvrsart edhgqyqcev wqenmnedgt fkkiqkqmss petvsitake
      421 snlavvmlmk davtegdalh vscsvsgfkg plsvswqhkk dpgasfsdvv slthegvmkd
      481 vgaryqsrnv qtfhspagnf tlqlgasavs dsgeykcivs ewtvqsngem kaitqsqqka
      541 itvksieslm vvsltsrtsn vpidspvqll crvrgprvsl alrwmfqphn stvqtnilsi
      601 shtgemtwra dqrnyqlniq arpedtrftl mvpraskqqk gqyqcqvday qkdvqkafkn
      661 snllavivhk pdskmsllsp tsrlettvdt daklecsvmk tttntsrftv awmfgsqvll
      721 tmdldavvkf gpaaglemdq rirleirqkq nfqmtiqqvr tsdsgqyhce veewlqdplv
      781 dwyslkkmsv stelvvkeke sklhvqkdnr mlnvtnhqag ftidcvidsq ssdksvfevt
      841 wfkvqkegqv aiftarrdgi lhsaiadrnl vfgrplathy kltvlqispt digqyycqve
      901 ewlltsntwk kfasdksgel sihvhtegek qidpllitla iaiplicflv lviifllrks
      961 hkkkyeismk yelkkmkkkk kkkdclwaet nvlngpstn
//
LOCUS       XP_026128357            1004 aa            linear   VRT 18-JUN-2025
DEFINITION  immunoglobulin superfamily member 2-like [Carassius auratus].
ACCESSION   XP_026128357
VERSION     XP_026128357.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272572.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1004
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1004
                     /product="immunoglobulin superfamily member 2-like"
                     /calculated_mol_wt=112767
     Region          <71..135
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          109..113
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          123..128
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          159..259
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          170..174
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..191
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          237..241
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          251..256
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          306..403
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          328..332
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          386..391
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          434..523
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          440..444
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          454..459
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          501..505
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          515..520
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          692..773
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          815..905
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          821..825
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          839..844
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          886..890
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          900..905
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..1004
                     /gene="LOC113109050"
                     /coded_by="XM_026272572.1:136..3150"
                     /db_xref="GeneID:113109050"
ORIGIN      
        1 mvdfwcqkwk lplllcltgl lqwdlcsgqi qvqiqkgply rvkgypisif cnttgftgps
       61 erdfefilkk qnmelnmist sdpnfayglf sgrirkkeiy verlsgssvv lwikdlqesd
      121 agdllcatlh tgggylgdyd deaklnviad tleasysgsp sqslsegdpl qlecqvssqt
      181 fqhthlsvtw flhgeedenp rpiitldkdl tvkpgagfed ryraglismd kvedttyrlk
      241 mpqvaqsdqg kffckaiewi qdpdrswtqi ahktttpcdv eikrievape agsfsvnlka
      301 skgplqegda ldircsvnaq nlpghffsvt wlkdqqrvaq igssgvltvf dsykdrenaa
      361 emravktshm dylltvrsar tedhgqyqce vwqenmnedg tfkkiqkqms spetvsitak
      421 esnlavvmlm kdavtegdal hvscsvsgfk gplsvswqhk kdpgasfsdv vslthegvmk
      481 dvgaryqsrn vqtfhspagn ftlqlgasai sdsgeykciv sewtvqsnge mkaitqsqqk
      541 aitvksiesl mvvsltsrts nvpidspvql lcrvrgprvs lalrwmfqph nstvqtnils
      601 ishtgemewr adqrnyqlni qaqpedtrft lmvpraskqq kgqyqcqvda yqkdvqkafk
      661 nsnllavivn kpdskmslfs ptsrlettvd tdaklecsvm ktttntsrft vtwmfgsqvl
      721 ltmdldavvk fgpaaglemd qrirleirqk qnfqmtiqqv rtsdsgqyhc eveewlqdpl
      781 gdwyslkkms vstelvvkek asdlkmnkad tqlkveegkq vklkcsvegi gsdptlrysl
      841 twmfnqyqss ssalltyshd grlkyksfds elegrlhfst pevgvfhlti hrsiqedrgr
      901 yycevqqyql dckgqwshka sdtsgftnvt vqligdsekq tdplgtalgv tiplicflvl
      961 viilllikdh krdselkkkk eclwaennpl tplpektcaa edys
//
LOCUS       XP_026128358             991 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128358
VERSION     XP_026128358.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272573.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..991
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X1"
                     /calculated_mol_wt=111403
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <336..611
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <509..769
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <705..965
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..991
                     /gene="LOC113109051"
                     /coded_by="XM_026272573.1:266..3241"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqlharevrk
      241 pgldtvecgk gehicllede ltetmpassq atlpcrnrlt apnkkwdqds elengdethe
      301 gqkllkespq saitgknkdd tgntngeldk nkensgtade aeennnskae ktnteveiqk
      361 fletqedkek sqilknksed eektpgetpe tlrdpdtkda dkneedwape ekkekeeenk
      421 eidnlksaeg elekhrknsk nadeesansk adktdteiei qkclqtqeem ekkcqilknn
      481 sedeekkpek ptedlgdqey knadknnsed eekehvdpsq nlgdqenkkn sdnegkehvd
      541 psqnlgdqen enaekknsdn egkehvdpsq nlgdqenena ekknsdnegk ehvdpsqnlg
      601 dqenkknsdn egkehvdpsq nlgdqenknn sdnegkehvd psqnlgdqen kknsdnegke
      661 hvdpsqnlgd qeneknsdne gkehvdpsqn lgdqenenns dnegkehvdp sqnlgdqenk
      721 knsdnegkeh vdpsqnlgdq eneknsdneg kehvdpsqnl gdqenenaek knsdnegkeh
      781 vdpsqnlgdq enkknsdneg kehvdpsqnl gdqenkknsd negkehvdps qnlgdqenkn
      841 adksksedee kghedptqkl geqatedthk needralkvk kekeeenkei antnkeilsp
      901 qsavtgritv dtgnveeqlh knekssqnen geqsteqqnk slsineddqr peredeekte
      961 kenhevtgil hadspskldt sdpslnlnme l
//
LOCUS       XP_026128359             986 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128359
VERSION     XP_026128359.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272574.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..986
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X2"
                     /calculated_mol_wt=110811
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <331..606
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <504..764
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <700..960
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..986
                     /gene="LOC113109051"
                     /coded_by="XM_026272574.1:265..3225"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqlrkpgldt
      241 vecgkgehic lledeltetm passqatlpc rnrltapnkk wdqdseleng dethegqkll
      301 kespqsaitg knkddtgntn geldknkens gtadeaeenn nskaektnte veiqkfletq
      361 edkeksqilk nksedeektp getpetlrdp dtkdadknee dwapeekkek eeenkeidnl
      421 ksaegelekh rknsknadee sanskadktd teieiqkclq tqeemekkcq ilknnsedee
      481 kkpekptedl gdqeyknadk nnsedeekeh vdpsqnlgdq enkknsdneg kehvdpsqnl
      541 gdqenenaek knsdnegkeh vdpsqnlgdq enenaekkns dnegkehvdp sqnlgdqenk
      601 knsdnegkeh vdpsqnlgdq enknnsdneg kehvdpsqnl gdqenkknsd negkehvdps
      661 qnlgdqenek nsdnegkehv dpsqnlgdqe nennsdnegk ehvdpsqnlg dqenkknsdn
      721 egkehvdpsq nlgdqenekn sdnegkehvd psqnlgdqen enaekknsdn egkehvdpsq
      781 nlgdqenkkn sdnegkehvd psqnlgdqen kknsdnegke hvdpsqnlgd qenknadksk
      841 sedeekghed ptqklgeqat edthkneedr alkvkkekee enkeiantnk eilspqsavt
      901 gritvdtgnv eeqlhkneks sqnengeqst eqqnkslsin eddqrpered eektekenhe
      961 vtgilhadsp skldtsdpsl nlnmel
//
LOCUS       XP_026128360             975 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128360
VERSION     XP_026128360.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272575.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..975
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..975
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X3"
                     /calculated_mol_wt=109591
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <320..595
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <493..753
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <689..949
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..975
                     /gene="LOC113109051"
                     /coded_by="XM_026272575.1:266..3193"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqlharevrk
      241 pgldtvecgk assqatlpcr nrltapnkkw dqdselengd ethegqkllk espqsaitgk
      301 nkddtgntng eldknkensg tadeaeennn skaektntev eiqkfletqe dkeksqilkn
      361 ksedeektpg etpetlrdpd tkdadkneed wapeekkeke eenkeidnlk saegelekhr
      421 knsknadees anskadktdt eieiqkclqt qeemekkcqi lknnsedeek kpekptedlg
      481 dqeyknadkn nsedeekehv dpsqnlgdqe nkknsdnegk ehvdpsqnlg dqenenaekk
      541 nsdnegkehv dpsqnlgdqe nenaekknsd negkehvdps qnlgdqenkk nsdnegkehv
      601 dpsqnlgdqe nknnsdnegk ehvdpsqnlg dqenkknsdn egkehvdpsq nlgdqenekn
      661 sdnegkehvd psqnlgdqen ennsdnegke hvdpsqnlgd qenkknsdne gkehvdpsqn
      721 lgdqenekns dnegkehvdp sqnlgdqene naekknsdne gkehvdpsqn lgdqenkkns
      781 dnegkehvdp sqnlgdqenk knsdnegkeh vdpsqnlgdq enknadksks edeekghedp
      841 tqklgeqate dthkneedra lkvkkekeee nkeiantnke ilspqsavtg ritvdtgnve
      901 eqlhknekss qnengeqste qqnkslsine ddqrperede ektekenhev tgilhadsps
      961 kldtsdpsln lnmel
//
LOCUS       XP_026128361             973 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X4 [Carassius
            auratus].
ACCESSION   XP_026128361
VERSION     XP_026128361.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272576.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..973
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X4"
                     /calculated_mol_wt=109459
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <318..593
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <491..751
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <687..947
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..973
                     /gene="LOC113109051"
                     /coded_by="XM_026272576.1:265..3186"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqcehiclle
      241 deltetmpas sqatlpcrnr ltapnkkwdq dselengdet hegqkllkes pqsaitgknk
      301 ddtgntngel dknkensgta deaeennnsk aektntevei qkfletqedk eksqilknks
      361 edeektpget petlrdpdtk dadkneedwa peekkekeee nkeidnlksa egelekhrkn
      421 sknadeesan skadktdtei eiqkclqtqe emekkcqilk nnsedeekkp ekptedlgdq
      481 eyknadknns edeekehvdp sqnlgdqenk knsdnegkeh vdpsqnlgdq enenaekkns
      541 dnegkehvdp sqnlgdqene naekknsdne gkehvdpsqn lgdqenkkns dnegkehvdp
      601 sqnlgdqenk nnsdnegkeh vdpsqnlgdq enkknsdneg kehvdpsqnl gdqeneknsd
      661 negkehvdps qnlgdqenen nsdnegkehv dpsqnlgdqe nkknsdnegk ehvdpsqnlg
      721 dqeneknsdn egkehvdpsq nlgdqenena ekknsdnegk ehvdpsqnlg dqenkknsdn
      781 egkehvdpsq nlgdqenkkn sdnegkehvd psqnlgdqen knadksksed eekghedptq
      841 klgeqatedt hkneedralk vkkekeeenk eiantnkeil spqsavtgri tvdtgnveeq
      901 lhknekssqn engeqsteqq nkslsinedd qrperedeek tekenhevtg ilhadspskl
      961 dtsdpslnln mel
//
LOCUS       XP_026128362             970 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X5 [Carassius
            auratus].
ACCESSION   XP_026128362
VERSION     XP_026128362.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272577.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..970
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..970
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X5"
                     /calculated_mol_wt=108999
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <315..590
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <488..748
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <684..944
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..970
                     /gene="LOC113109051"
                     /coded_by="XM_026272577.1:266..3178"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqlrkpgldt
      241 vecgkassqa tlpcrnrlta pnkkwdqdse lengdetheg qkllkespqs aitgknkddt
      301 gntngeldkn kensgtadea eennnskaek tnteveiqkf letqedkeks qilknksede
      361 ektpgetpet lrdpdtkdad kneedwapee kkekeeenke idnlksaege lekhrknskn
      421 adeesanska dktdteieiq kclqtqeeme kkcqilknns edeekkpekp tedlgdqeyk
      481 nadknnsede ekehvdpsqn lgdqenkkns dnegkehvdp sqnlgdqene naekknsdne
      541 gkehvdpsqn lgdqenenae kknsdnegke hvdpsqnlgd qenkknsdne gkehvdpsqn
      601 lgdqenknns dnegkehvdp sqnlgdqenk knsdnegkeh vdpsqnlgdq eneknsdneg
      661 kehvdpsqnl gdqenennsd negkehvdps qnlgdqenkk nsdnegkehv dpsqnlgdqe
      721 neknsdnegk ehvdpsqnlg dqenenaekk nsdnegkehv dpsqnlgdqe nkknsdnegk
      781 ehvdpsqnlg dqenkknsdn egkehvdpsq nlgdqenkna dksksedeek ghedptqklg
      841 eqatedthkn eedralkvkk ekeeenkeia ntnkeilspq savtgritvd tgnveeqlhk
      901 nekssqneng eqsteqqnks lsineddqrp eredeektek enhevtgilh adspskldts
      961 dpslnlnmel
//
LOCUS       XP_026128363             968 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X6 [Carassius
            auratus].
ACCESSION   XP_026128363
VERSION     XP_026128363.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272578.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..968
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..968
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X6"
                     /calculated_mol_wt=108839
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <288..532
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <473..753
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <682..942
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..968
                     /gene="LOC113109051"
                     /coded_by="XM_026272578.1:272..3178"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqlharevrk
      241 pgldtvecgk gehicllede ltetmpassq atlpcrnrlt apnkkwdqds elengdethe
      301 gqkllkespq saitgknkdd tgntngeldk nkensgtade aeennnskae ktnteveiqk
      361 fletqedkek sqilknksed eektpgetpe tlrdpdtkda dkneedwape ekkekeeenk
      421 eidnlksaeg elekhrknsk nadeesansk adktdteiei qkclqtqeem ekkcqilknn
      481 sedeekkpek ptedlgdqey knadknnsed eekehvdpsq nlgdqenkkn sdnegkehvd
      541 psqnlgdqen enaekknsdn egkehvdpsq nlgdqenena ekknsdnegk ehvdpsqnlg
      601 dqenknnsdn egkehvdpsq nlgdqenkkn sdnegkehvd psqnlgdqen eknsdnegke
      661 hvdpsqnlgd qenennsdne gkehvdpsqn lgdqenkkns dnegkehvdp sqnlgdqene
      721 knsdnegkeh vdpsqnlgdq enenaekkns dnegkehvdp sqnlgdqenk knsdnegkeh
      781 vdpsqnlgdq enkknsdneg kehvdpsqnl gdqenknadk sksedeekgh edptqklgeq
      841 atedthknee dralkvkkek eeenkeiant nkeilspqsa vtgritvdtg nveeqlhkne
      901 kssqnengeq steqqnksls ineddqrper edeekteken hevtgilhad spskldtsdp
      961 slnlnmel
//
LOCUS       XP_026128364             957 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X7 [Carassius
            auratus].
ACCESSION   XP_026128364
VERSION     XP_026128364.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272579.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..957
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..957
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X7"
                     /calculated_mol_wt=107617
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <302..577
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <475..735
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <671..931
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..957
                     /gene="LOC113109051"
                     /coded_by="XM_026272579.1:265..3138"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqsssqatlp
      241 crnrltapnk kwdqdselen gdethegqkl lkespqsait gknkddtgnt ngeldknken
      301 sgtadeaeen nnskaektnt eveiqkflet qedkeksqil knksedeekt pgetpetlrd
      361 pdtkdadkne edwapeekke keeenkeidn lksaegelek hrknsknade esanskadkt
      421 dteieiqkcl qtqeemekkc qilknnsede ekkpekpted lgdqeyknad knnsedeeke
      481 hvdpsqnlgd qenkknsdne gkehvdpsqn lgdqenenae kknsdnegke hvdpsqnlgd
      541 qenenaekkn sdnegkehvd psqnlgdqen kknsdnegke hvdpsqnlgd qenknnsdne
      601 gkehvdpsqn lgdqenkkns dnegkehvdp sqnlgdqene knsdnegkeh vdpsqnlgdq
      661 enennsdneg kehvdpsqnl gdqenkknsd negkehvdps qnlgdqenek nsdnegkehv
      721 dpsqnlgdqe nenaekknsd negkehvdps qnlgdqenkk nsdnegkehv dpsqnlgdqe
      781 nkknsdnegk ehvdpsqnlg dqenknadks ksedeekghe dptqklgeqa tedthkneed
      841 ralkvkkeke eenkeiantn keilspqsav tgritvdtgn veeqlhknek ssqnengeqs
      901 teqqnkslsi neddqrpere deektekenh evtgilhads pskldtsdps lnlnmel
//
LOCUS       XP_026128365             954 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X8 [Carassius
            auratus].
ACCESSION   XP_026128365
VERSION     XP_026128365.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272580.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..954
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X8"
                     /calculated_mol_wt=107301
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <303..574
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <472..732
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <668..928
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..954
                     /gene="LOC113109051"
                     /coded_by="XM_026272580.1:231..3095"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvmflvyf tcfclyqdlv fcdeygesgn kitlnpvirg tpeeimwthn gnkvleydgk
       61 qmdtygsfkd rveldfetgq ltiiklnnqd sgtykseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafylyrrkr pqlrkpeldt
      241 vergkesiad kkfdqesele nedethegqk llkkspqsai tgknkdntan tngeldknme
      301 nsgnadeaee sanseaektd sevesqkfle tqeekeksqv lenksedekk tpetlgeqdn
      361 edadkneenq ipeekkekke enketdnlks aegelekhrk nsknadeesa nskadktdte
      421 ieiqkclqtq eemekkcqil knnsedeekk pekptedlgd qeyknadknn sedeekehvd
      481 psqnlgdqen kknsdnegke hvdpsqnlgd qenenaekkn sdnegkehvd psqnlgdqen
      541 enaekknsdn egkehvdpsq nlgdqenkkn sdnegkehvd psqnlgdqen knnsdnegke
      601 hvdpsqnlgd qenkknsdne gkehvdpsqn lgdqenekns dnegkehvdp sqnlgdqene
      661 nnsdnegkeh vdpsqnlgdq enkknsdneg kehvdpsqnl gdqeneknsd negkehvdps
      721 qnlgdqenen aekknsdneg kehvdpsqnl gdqenkknsd negkehvdps qnlgdqenkk
      781 nsdnegkehv dpsqnlgdqe nknadkskse deekghedpt qklgeqated thkneedral
      841 kvkkekeeen keiantnkei lspqsavtgr itvdtgnvee qlhknekssq nengeqsteq
      901 qnkslsined dqrperedee ktekenhevt gilhadspsk ldtsdpslnl nmel
//
LOCUS       XP_026128366             907 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein DDB_G0290685-like isoform X9 [Carassius
            auratus].
ACCESSION   XP_026128366
VERSION     XP_026128366.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272581.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..907
                     /product="uncharacterized protein DDB_G0290685-like
                     isoform X9"
                     /calculated_mol_wt=101881
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <326..611
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <509..769
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     Region          <705..>902
                     /region_name="2A1904"
                     /note="K+-dependent Na+/Ca+ exchanger; TIGR00927"
                     /db_xref="CDD:273344"
     CDS             1..907
                     /gene="LOC113109051"
                     /coded_by="XM_026272581.1:267..2990"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqlharevrk
      241 pgldtvecgk gehicllede ltetmpassq atlpcrnrlt apnkkwdqds elengdethe
      301 gqkllkespq saitgknkdd tgntngeldk nkensgtade aeennnskae ktnteveiqk
      361 fletqedkek sqilknksed eektpgetpe tlrdpdtkda dkneedwape ekkekeeenk
      421 eidnlksaeg elekhrknsk nadeesansk adktdteiei qkclqtqeem ekkcqilknn
      481 sedeekkpek ptedlgdqey knadknnsed eekehvdpsq nlgdqenkkn sdnegkehvd
      541 psqnlgdqen enaekknsdn egkehvdpsq nlgdqenena ekknsdnegk ehvdpsqnlg
      601 dqenkknsdn egkehvdpsq nlgdqenknn sdnegkehvd psqnlgdqen kknsdnegke
      661 hvdpsqnlgd qeneknsdne gkehvdpsqn lgdqenenns dnegkehvdp sqnlgdqenk
      721 knsdnegkeh vdpsqnlgdq eneknsdneg kehvdpsqnl gdqenenaek knsdnegkeh
      781 vdpsqnlgdq enkknsdneg kehvdpsqnl gdqenkknsd negkehvdps qnlgdqenkn
      841 adksksedee kghedptqkl geqatedthk needralkvk kekeeenkei antnkdspsk
      901 mdtsvps
//
LOCUS       XP_026128367             689 aa            linear   VRT 18-JUN-2025
DEFINITION  myb-like protein X isoform X10 [Carassius auratus].
ACCESSION   XP_026128367
VERSION     XP_026128367.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272582.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..689
                     /product="myb-like protein X isoform X10"
                     /calculated_mol_wt=78307
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <293..509
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     CDS             1..689
                     /gene="LOC113109051"
                     /coded_by="XM_026272582.1:277..2346"
                     /db_xref="GeneID:113109051"
ORIGIN      
        1 madvkflvyf tcfclyqdlv fcdeygesgn kitlnpvihg kpeeimwthn gnkvleydgk
       61 qmdtygsfkd rvdldfetgq ltiiklnnqd sgkylseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtqpsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafyfyrrkr eqlharevrk
      241 pgldtvecgk gehicllede ltetmpassq atlpcrnrlt apnkkwdqds elengdethe
      301 gqkllkespq saitgknkdd tgntngeldk nkensgtade aeennnskae ktnteveiqk
      361 fletqedkek sqilknksed eektpgetpe tlrdpdtkda dkneedwape ekkekeeenk
      421 eidnlksaeg elekqqknsk nadeenansk adktnkeiei qkslqtqeei eksqipknns
      481 edeekkpekq tetlgeqenr nadkneedrv pkvkkekeee nkeidnmnke ivspqsavtg
      541 ritvdtgnve erhkneksrq nengeqsteq qnkslsined dqrpegerge eektekenln
      601 vtgilhtdsp skldtsvpss tmkmelennq aasfpqeedd dgeqtdksse seqgrkekkv
      661 fqklkrqknn fyiyqkhkql hiwckrtrk
//
LOCUS       XP_026128369             746 aa            linear   VRT 18-JUN-2025
DEFINITION  prostaglandin F2 receptor negative regulator-like [Carassius
            auratus].
ACCESSION   XP_026128369
VERSION     XP_026128369.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272584.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..746
                     /product="prostaglandin F2 receptor negative
                     regulator-like"
                     /calculated_mol_wt=82785
     Region          35..141
                     /region_name="V-set"
                     /note="Immunoglobulin V-set domain; pfam07686"
                     /db_xref="CDD:462230"
     Region          157..258
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          163..167
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          177..186
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          219..233
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          243..248
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          570..663
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     CDS             1..746
                     /gene="LOC113109053"
                     /coded_by="XM_026272584.1:1..2241"
                     /db_xref="GeneID:113109053"
ORIGIN      
        1 mdkgtglrpv iliialvsfc egrvvkvpvg plvhvegqav sihcdvsdyq gprdqefews
       61 lvlpgnnflh listfdgnfa dssvrdrvns gdisykrlgd aavelkfkki ratdsgmyrc
      121 stpstdsvis gnyhddvelk vigdslkvap aipksavseg esvelqcnat rgftehtfls
      181 vtwsirkgss pleeiltfgp ddkikvgrny frrytdggll ldlrgggfyg lvlkrarpsd
      241 qgeyvcvaqe wvrqgeegrn wrmileksee mgnvtvtpte lqfkvtltas lnpqstsept
      301 elrcevvdll hlqdgrlgvt wsystntsgd vsqkkltias lneqgaliad sqyqqrldtg
      361 diavtrresn ifilrmlqtr dadmgsysca vtawkptqqs gwekamevqs tpvtvqwtpk
      421 ipdlqvvahr vreastagst femscrvtgq nlknpgysvl irfeetlggk srkvlslsqd
      481 svlqleewse psridsvvle ktgqleyrfr lygaqvtdrg lyycdvtawt rhqsqdwika
      541 isaesnkiei afvhtgpvfn isihseannv lpgntvqmkc iisilqaspn tgdmafevrw
      601 fqktdravdn gvqplismdr wgvvkktdsn dtsleridrn tfvlslhkik drdvgeyycs
      661 atpwllspat gawnkekdlt sassslsvkt efweslmmpv gyglaaavia gllsvllgla
      721 vahccfsrnp ihtprprnkl mdldmd
//
LOCUS       XP_026128370             362 aa            linear   VRT 18-JUN-2025
DEFINITION  immunoglobulin superfamily member 3-like [Carassius auratus].
ACCESSION   XP_026128370
VERSION     XP_026128370.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272585.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..362
                     /product="immunoglobulin superfamily member 3-like"
                     /calculated_mol_wt=40777
     CDS             1..362
                     /gene="LOC113109054"
                     /coded_by="XM_026272585.1:102..1190"
                     /db_xref="GeneID:113109054"
ORIGIN      
        1 mgqyycqvee wlltantwkk lasdksgels iyvhteeskl svqknnrmin itndqtsfti
       61 dcvidsqssd tsgfevtwfk vqeegpltmf sarhdgtlhs aipdknllfg rplathyklt
      121 vlqisptdig qyycqveewl ltantwkkla sdksgelsiy vhteesklhv qknnrminit
      181 ndqtsftidc vidsqssdas vfevtwfkvq edgplimfsa rhdgtlhsai pdknllfgrp
      241 lathykltvl qisptdigqy ycqveewllt antwkklasd ksgelsiyvh tegdskkqtd
      301 plgtalgvti plicflvlvi illlikdhkr nselkkkkds lwaennpltp lpegtcvaed
      361 hs
//
LOCUS       XP_026128371             323 aa            linear   VRT 18-JUN-2025
DEFINITION  T-cell surface antigen CD2 [Carassius auratus].
ACCESSION   XP_026128371
VERSION     XP_026128371.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272586.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..323
                     /product="T-cell surface antigen CD2"
                     /calculated_mol_wt=36157
     Region          27..103
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          35..41
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          49..53
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          78..82
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          92..97
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          132..191
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cd00096"
                     /db_xref="CDD:409353"
     Region          132..136
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          145..149
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          160..164
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          174..179
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          188..191
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..323
                     /gene="LOC113109055"
                     /coded_by="XM_026272586.1:260..1231"
                     /db_xref="GeneID:113109055"
ORIGIN      
        1 mmpnliitll inlifmfstg kcvssciyka agdkvvisfn daklqkdnel rwthdkqkvy
       61 irkgsqikvn klnvnedgsl ilenvqkdqs geykviiydt dgkliketvq qlcvlepvpe
      121 ptvifecvek gvylncsavn ndevvvswmk ngiktnatra ilhvtsselk pgdtfsctvs
      181 nqiskkstev vkpgcsftdl htttanedkt reinnqseni nikgdyentf lglelwlmlv
      241 iligggsfli lfiiclvcvc rwygrnkrka keeeeyrlta lmpdhtnppd eqymqttsqr
      301 ssksqrplpp lpspqspscv gpp
//
LOCUS       XP_026128372             313 aa            linear   VRT 18-JUN-2025
DEFINITION  immunoglobulin superfamily member 2-like [Carassius auratus].
ACCESSION   XP_026128372
VERSION     XP_026128372.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272587.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..313
                     /product="immunoglobulin superfamily member 2-like"
                     /calculated_mol_wt=35214
     Region          <71..137
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          109..113
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          123..128
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          159..259
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          170..174
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..191
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          237..241
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          251..256
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..313
                     /gene="LOC113109056"
                     /coded_by="XM_026272587.1:65..1006"
                     /db_xref="GeneID:113109056"
ORIGIN      
        1 mvdfwcqkwk lplllcltgl lqwdlcsgqi qvqiqkgply rvkgypisif cnvtgftgps
       61 erdfefilkk qnmtlniist sdpnfayglf sgrirkkeiy verlsgssvv lwikdlqesd
      121 agdllcatkh tggayfgdyd deaklnviad tleasysgsp sqslsegdpl qlecqvssqt
      181 fqhthlsvtw flhdeddknp rpiitldkdl tvkpgagfed cyraglismd kvedttyrlk
      241 mpqvqqsdqg kffckaieri qdpdrswtqi ahkttkacdv eikflactlt tasstpivrm
      301 cqytnrlnet gqi
//
LOCUS       XP_026128373             313 aa            linear   VRT 18-JUN-2025
DEFINITION  immunoglobulin superfamily member 2-like [Carassius auratus].
ACCESSION   XP_026128373
VERSION     XP_026128373.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272588.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..313
                     /product="immunoglobulin superfamily member 2-like"
                     /calculated_mol_wt=35498
     Region          159..259
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          170..174
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..191
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          237..241
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          251..256
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..313
                     /gene="LOC113109057"
                     /coded_by="XM_026272588.1:51..992"
                     /db_xref="GeneID:113109057"
ORIGIN      
        1 mvdfwcqkwk lplllcltgl lqwdlcsgqi qvqiqkgply rvkgypisif ckvtgftgps
       61 erdfefilkk qnmplniist sdpnfayglf sgrirkkeiy verlsgssvv lwikdlqekd
      121 agdqlcvtkh tggeyfgdye deaklnviad tleasysgsp sqslsegdpl qlecqvssqt
      181 fqhthlsvtw flhdeddknp rpiitldkdl tvkpgagfed ryraglismd kvedttyrlk
      241 mpqvqqsdqg kffckaiewi qdpdrswtqi ahkttkacdv eikffactlt tasstpivrm
      301 cqytnrlnet gqi
//
LOCUS       XP_026128374             313 aa            linear   VRT 18-JUN-2025
DEFINITION  immunoglobulin superfamily member 2-like [Carassius auratus].
ACCESSION   XP_026128374
VERSION     XP_026128374.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272589.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..313
                     /product="immunoglobulin superfamily member 2-like"
                     /calculated_mol_wt=35371
     Region          159..259
                     /region_name="IgV"
                     /note="Immunoglobulin variable domain (IgV); cd00099"
                     /db_xref="CDD:409355"
     Region          162..164
                     /region_name="Ig strand A'"
                     /note="Ig strand A' [structural motif]"
                     /db_xref="CDD:409355"
     Region          168..176
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409355"
     Region          176..186
                     /region_name="CDR1"
                     /note="CDR1 [structural motif]"
                     /db_xref="CDD:409355"
     Site            order(186..187,189,257)
                     /site_type="other"
                     /note="antigen binding site [polypeptide binding]"
                     /db_xref="CDD:409355"
     Region          187..202
                     /region_name="FR2"
                     /note="FR2 [structural motif]"
                     /db_xref="CDD:409355"
     Region          187..193
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409355"
     Region          200..203
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409355"
     Region          203..222
                     /region_name="CDR2"
                     /note="CDR2 [structural motif]"
                     /db_xref="CDD:409355"
     Region          222..232
                     /region_name="Ig strand D"
                     /note="Ig strand D [structural motif]"
                     /db_xref="CDD:409355"
     Region          228..256
                     /region_name="FR3"
                     /note="FR3 [structural motif]"
                     /db_xref="CDD:409355"
     Region          236..242
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409355"
     Region          250..257
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409355"
     CDS             1..313
                     /gene="LOC113109058"
                     /coded_by="XM_026272589.1:13..954"
                     /db_xref="GeneID:113109058"
ORIGIN      
        1 mvdfwcqkwk lplllcltgl lqwdlcsgqi qvqiqegply rvkgypisif cnvtgftgps
       61 erdfefilkk qnmelniist kdpsfaygmf sgrirkkeiy verlsgssvv lwikdlqekd
      121 agdllcvtkh tggayygdyd deaklnviad tleasysgsp sqslsegdpl qlecqvssqt
      181 fqhthlsvtw flhdeddknp rpiitldkdl tvkpgagfed ryraglismd kvedttyrlk
      241 mpqvqqsdqg kffckaiewi qdpdrswtqi ahkttkacdv eikflactlt tasstpivrm
      301 cqytnrlngt gqi
//
LOCUS       XP_026128375             276 aa            linear   VRT 18-JUN-2025
DEFINITION  hepatocyte cell adhesion molecule-like [Carassius auratus].
ACCESSION   XP_026128375
VERSION     XP_026128375.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272590.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..276
                     /product="hepatocyte cell adhesion molecule-like"
                     /calculated_mol_wt=30797
     Region          26..102
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          34..40
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          49..52
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          77..81
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          91..96
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          131..190
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cd00096"
                     /db_xref="CDD:409353"
     Region          131..135
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          144..148
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          159..163
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          173..178
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..190
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..276
                     /gene="LOC113109059"
                     /coded_by="XM_026272590.1:65..895"
                     /db_xref="GeneID:113109059"
ORIGIN      
        1 mllnltsvlf ilifmfppgk fvssciykaa gdkvvisfdd aksqedndlr wthnkqkvyi
       61 rkgsqiklnk lnvsedgsli leniqkdqsg eykgviydad gklitetvqe lcvlepvaep
      121 ivlvecveng vnlnctavnv tevvvswmkn gkkanmthav lhissselkp gdtfsctlrn
      181 qiskksaknv epecsetdks ekkylfgldl wwtlviltgg ggfllilfii clvcvscccr
      241 pnkrkakree qhqlvplmpy ylnqpddqqk pvtsfg
//
LOCUS       XP_026128376             250 aa            linear   VRT 18-JUN-2025
DEFINITION  CD48 antigen-like [Carassius auratus].
ACCESSION   XP_026128376
VERSION     XP_026128376.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272591.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..250
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..250
                     /product="CD48 antigen-like"
                     /calculated_mol_wt=28051
     Region          20..114
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          32..36
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          44..48
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          79..83
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          93..98
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..250
                     /gene="LOC113109061"
                     /coded_by="XM_026272591.1:96..848"
                     /db_xref="GeneID:113109061"
ORIGIN      
        1 madvmflvyf tcfclyqdlv fcdeygesgn qiklnpfihg kpeeilwthn gnkvleydgk
       61 qmdtygsfkd rveldfetgq ltiiklnnqd sgtykseivi skkvhtssht ltvldalpep
      121 lvtcevdets nvkklscsve sqtepsyews gsdvkqpgpt lvvneqeenl nsvytctvks
      181 kagsrttdfn lqdcatgran pavlvpvliv illliillaa lafylyrrkr pqckchenif
      241 nispskrifs
//
LOCUS       XP_026128378            1391 aa            linear   VRT 18-JUN-2025
DEFINITION  immunoglobulin superfamily member 3-like [Carassius auratus].
ACCESSION   XP_026128378
VERSION     XP_026128378.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272593.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1391
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1391
                     /product="immunoglobulin superfamily member 3-like"
                     /calculated_mol_wt=157222
     Region          46..137
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          47..51
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          109..113
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          123..128
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          159..259
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          170..174
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..191
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          237..241
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          251..256
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          298..386
                     /region_name="Ig_3"
                     /note="Immunoglobulin domain; pfam13927"
                     /db_xref="CDD:464046"
     Region          557..638
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          558..562
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          575..579
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          618..622
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          632..637
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          680..770
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          686..690
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          704..709
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          751..755
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          765..770
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          822..906
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          822..825
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          835..842
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          881..885
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          895..900
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          946..1034
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          954..958
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          972..976
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          1017..1021
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..1391
                     /gene="LOC113109063"
                     /coded_by="XM_026272593.1:46..4221"
                     /db_xref="GeneID:113109063"
ORIGIN      
        1 mvdfwcqkwk lplllcltgl lqwdlcsgqi qvqiqkgply rmkgypisis cnvtgftgps
       61 kqdfefilkk qnmelnmist sdpnfaygmf sdrirkkeiy ierlsgssvi lwikalqend
      121 agdllcatlh tggeyfgdyg aesklnviad tleasysasp sqslsegdpl qlecqvssqt
      181 cqhshlsvtw flhgeddenp rpiitldkdl tvkpgagfed ryraglismd kvedttyrlk
      241 mpqvqqsdqg kffckaiewi qdpdrswtqi ahkttkacdv eikriesnla vvmlmndavt
      301 egdalhvscs vsgfkgplsv swqhkkalra ffsdvvslth egvmkdvgar yqsrnvqtfh
      361 spagsftlql gvssisdsge ykcivsewtv qsngemkait qsqqkaitvk sveslmavsl
      421 tsrttivpid spvqllcrvr gpkvslalrw mfqphnsaaq inivsishtg emewradqrn
      481 yqlniqaqpg dtrftlmvpr askqqegqyq cqvdayqkdv qkafknsnll avivnkpdsk
      541 msllsptsrl ettvdtdakl ecsvmktttn tsrftvtwmf gsqvlltmdl davvkfgpaa
      601 glemdqrirl eirqkqnfql tiqqvrtsds gqyhceveew lqdplgdwys lkkmsvstel
      661 vvkekasyfk mnkadtqlkv eegkqvklkc svegigsdpt lrysltwmfn qyqsttsall
      721 tyshdgllky ksfdselvgr lhfstpevgv fnltihrsiq edrghyycev qqyqldckgq
      781 wsrkardksg ftnvtvqlie nklqvnkeek sltitnlqag ftidcviksr ssdkslfevt
      841 wsrglinerp viifnasrdg tlhsaiddke lvfgrpsamr ykltvpnvnp tdtglyhcqv
      901 vewiqtaank wrsigqdmsg kisvhvdtee qqknfsftmd kkdnnldike geqfdlecsl
      961 niekddpthh yslrwvfnrp gstsgiplls yshdgrlqyh sgnqdrlrfs rpnsdtfhla
     1021 vlnsdkadsg syqcrveqyq hdcngqwkpm araqsgtttv tvrsierklr vqkdnqmlni
     1081 tnhqtsftid cvidsqssdt svfevtwfkv qeegpltmfs arhdgtlhsa ipdknllfgr
     1141 plathykltv lqisptdmgq yycqveewll tsntwkklas dksgelsiyv hteesklhvq
     1201 knnrminitn dqtsftidcv idsqssdasv fevtwfkvqe dgpltmfsar hdgtlhsaip
     1261 dknllfgrpl athykltvlq isptdigqyy cqveewllta ntwkklasdk sgelsiyvht
     1321 egdsekqtdp lgtalgvtip licflvlvii lllikdhkrn selkkkkecl waennpltpl
     1381 pegtcvaedh s
//
LOCUS       XP_026128379             319 aa            linear   VRT 18-JUN-2025
DEFINITION  gastrula zinc finger protein XlCGF8.2DB [Carassius auratus].
ACCESSION   XP_026128379
VERSION     XP_026128379.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272594.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..319
                     /product="gastrula zinc finger protein XlCGF8.2DB"
                     /calculated_mol_wt=36071
     Region          12..32
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          <42..220
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          51..71
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          79..99
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(84,86,88,90..91,94..95,98,112,114,118..119,122..123,
                     126,140,142,144,146..147,150..151,154)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          92..114
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          107..127
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          119..144
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          131..>179
                     /region_name="SUF4-like"
                     /note="N-terminal domain of Oryza sativa transcription
                     factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana
                     SUF4 (AtSUF4), and similar proteins; cd20908"
                     /db_xref="CDD:411020"
     Region          135..156
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:411020"
     Region          135..155
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(140,146,153,155,162,169)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411020"
     Region          163..180
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          191..211
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          247..267
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275370"
     CDS             1..319
                     /gene="LOC113109064"
                     /coded_by="XM_026272594.1:337..1296"
                     /db_xref="GeneID:113109064"
ORIGIN      
        1 mshsskprsh pcglcdksfa qismltrhqq lhtsrlvlhk rshaaekpht crlcsktfis
       61 sahlalhlrs hsgerkykcs vcskmfmqss qlmrhktiht gekpfkcpdc nkcfgrashl
      121 kthrrlhtge kpfkctqcer aftqkaglii hlrlhtgerp fkcekcgkaf rtsahllnhq
      181 alelgegryt catcnkgfrs vsmlkqheks hqgsgmlccs vcsgafahss ylqlklhlqn
      241 geqlfhckvc nkifvkmstf ekhcrkhqte mdgcedrevk eeddppfelh tavsptpsts
      301 evntrsktra kikstaess
//
LOCUS       XP_026128380            1591 aa            linear   VRT 18-JUN-2025
DEFINITION  disco-interacting protein 2 homolog A isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128380
VERSION     XP_026128380.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272595.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1591
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1591
                     /product="disco-interacting protein 2 homolog A isoform
                     X1"
                     /calculated_mol_wt=173993
     Region          20..134
                     /region_name="DMAP_binding"
                     /note="DMAP1-binding Domain; pfam06464"
                     /db_xref="CDD:368923"
     Region          372..948
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(533,536..541,543..544)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(536,656..657,715..720,813,825,828,839,928)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(536,577..578,628,630..631,634,656..657,675..680,813,
                     825,828,836..839,909)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(577,630..631,634,656,836..838,896,909)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Region          1023..1587
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(1172,1175..1180,1182..1183)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(1175,1301..1302,1356..1361,1452,1474,1477,1488,1567)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(1175,1216..1217,1267,1269..1270,1273,1301..1302,
                     1319..1324,1452,1474,1477,1485..1488,1548)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(1216,1269..1270,1273,1301,1485..1487,1535,1548)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     CDS             1..1591
                     /gene="dip2a"
                     /coded_by="XM_026272595.1:371..5146"
                     /db_xref="GeneID:113109065"
ORIGIN      
        1 maersstgll mmmldpspai amtlpaevre klaelelels egditqkgye kkrgkllapy
       61 ipqiqgvdps lqiehriqts sqvappgskq nkprvansrd ecfrsdlhte avqaalakyk
      121 erkmpmpskr rsvlvqssve actppdtssa sedegslrrq griassspyq ahpsvehwfn
      181 rviqgsstss sasstsshpg grphhatntt sasaatvlad lmahtqldnh sappdvtgls
      241 ersvhaerpq vasmrglprg ythtsvmeta dgtdkgdgea ldgvpvnsrv sskiqqllnt
      301 lkrpkrpplr effvddfeel ldvqhpdpnq pkpeggemrp lngdplgvvt nwppsllasl
      361 qrwgttqpks pcltaldnag kpiytltygk lwtqsqklay tllnklstrn epllrpgdrv
      421 alvfpnndpv mfmvafyacl laelvpvpie vpltrkdags qqvgfllgsc gvtlalttda
      481 cqkglpkaqt gevvtfkgwp rllwfvtdgk hvakppkdwh ppirdacnei ayieyktske
      541 gstmgitvsh samlahchal tqacgytege iitnvldfkr daglwhgvlt svmnrmhvis
      601 ipyslmkvnp lswiqkvhty karvavvksr dmhwsllaqr dqrdislssl rmlivadgan
      661 pwsisscdaf lnvfqarglr pevicpcass seamtvairr ppemgvpppg kavlsmsgls
      721 ygvirvdtee klsvltvqdv gqvmpgalvc virlegtpyl crtdevgeic vsssstgisy
      781 yglpgmtknv fetipvtssg apisdrpftr tsllgfigpd nlvfvvgkmd glmvvsgrrh
      841 naddvvatal avepmkfvyr griavfslsv lhderivvva eqrpdaseed sfqwmsrvlq
      901 aidsihqvgv yclalvpant lpkaplggih isetkqrfle galhpcnvlm cphtcvtnlp
      961 kprqkqpgte vgpasmivgn lvagkriaqa cgrdvsqled ndqflymqdv lqwraqatpd
     1021 hplflllnak gtvantascv qlhkraerva valmergrln tgdhvalvyp pgvdliatfy
     1081 gclyagcvpv tvrpphpqnl tttlptvkmi vevsksvcil ttqaimkllk skeaaaavdi
     1141 ktwplildtd dlprkripqi ykpptpemla yldfsvsttg ilagvkmsha atsalcrsvk
     1201 lqcelypsrq iaicldpycg lgfalwclcs vysghqsilv ppleletnps lwlsavsqfk
     1261 vrvtfcsysv memctkalgs qtealrlrsv nlscvrtcmv vaeerpritl tqsfskifkd
     1321 lglssravst tfgcrvnvai clqgtsgpdp ttvyldmral rhdrvrlver gsphslplte
     1381 sgkilpgvkv iiantetkgp lgdshlgeiw vssphnatgy ytvygeealh adhfstrlsf
     1441 gdtqtvwart gylgflrrte ltdasgerhd alyvvgslde tlelrgmryh pidietsvir
     1501 shksiaecav ftwtnllvvv velegseqea ldlvalvtnv vleehylivg vvvvvdpgvi
     1561 pinsrgekqr mhlrdgflad qldpiyvayn m
//
LOCUS       XP_026128381            1580 aa            linear   VRT 18-JUN-2025
DEFINITION  disco-interacting protein 2 homolog A isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128381
VERSION     XP_026128381.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272596.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1580
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1580
                     /product="disco-interacting protein 2 homolog A isoform
                     X2"
                     /calculated_mol_wt=172934
     Region          20..134
                     /region_name="DMAP_binding"
                     /note="DMAP1-binding Domain; pfam06464"
                     /db_xref="CDD:368923"
     Region          361..937
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(522,525..530,532..533)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(525,645..646,704..709,802,814,817,828,917)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(525,566..567,617,619..620,623,645..646,664..669,802,
                     814,817,825..828,898)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(566,619..620,623,645,825..827,885,898)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Region          1012..1576
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(1161,1164..1169,1171..1172)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(1164,1290..1291,1345..1350,1441,1463,1466,1477,1556)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(1164,1205..1206,1256,1258..1259,1262,1290..1291,
                     1308..1313,1441,1463,1466,1474..1477,1537)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(1205,1258..1259,1262,1290,1474..1476,1524,1537)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     CDS             1..1580
                     /gene="dip2a"
                     /coded_by="XM_026272596.1:371..5113"
                     /db_xref="GeneID:113109065"
ORIGIN      
        1 maersstgll mmmldpspai amtlpaevre klaelelels egditqkgye kkrgkllapy
       61 ipqiqgvdps lqiehriqts sqvappgskq nkprvansrd ecfrsdlhte avqaalakyk
      121 erkmpmpskr rsvlvqssve actppdtssa sedegslrrq griassspyq ahpsvehwfn
      181 rviqgsstss sasstsshpg grphhatntt sasaatvlad lmahtqldnh sappdvtgls
      241 ersvhaerpq vasmrglprg ythtsvmeta dgvpvnsrvs skiqqllntl krpkrpplre
      301 ffvddfeell dvqhpdpnqp kpeggemrpl ngdplgvvtn wppsllaslq rwgttqpksp
      361 cltaldnagk piytltygkl wtqsqklayt llnklstrne pllrpgdrva lvfpnndpvm
      421 fmvafyacll aelvpvpiev pltrkdagsq qvgfllgscg vtlalttdac qkglpkaqtg
      481 evvtfkgwpr llwfvtdgkh vakppkdwhp pirdacneia yieyktskeg stmgitvshs
      541 amlahchalt qacgytegei itnvldfkrd aglwhgvlts vmnrmhvisi pyslmkvnpl
      601 swiqkvhtyk arvavvksrd mhwsllaqrd qrdislsslr mlivadganp wsisscdafl
      661 nvfqarglrp evicpcasss eamtvairrp pemgvpppgk avlsmsglsy gvirvdteek
      721 lsvltvqdvg qvmpgalvcv irlegtpylc rtdevgeicv sssstgisyy glpgmtknvf
      781 etipvtssga pisdrpftrt sllgfigpdn lvfvvgkmdg lmvvsgrrhn addvvatala
      841 vepmkfvyrg riavfslsvl hderivvvae qrpdaseeds fqwmsrvlqa idsihqvgvy
      901 clalvpantl pkaplggihi setkqrfleg alhpcnvlmc phtcvtnlpk prqkqpgtev
      961 gpasmivgnl vagkriaqac grdvsqledn dqflymqdvl qwraqatpdh plflllnakg
     1021 tvantascvq lhkraervav almergrlnt gdhvalvypp gvdliatfyg clyagcvpvt
     1081 vrpphpqnlt ttlptvkmiv evsksvcilt tqaimkllks keaaaavdik twplildtdd
     1141 lprkripqiy kpptpemlay ldfsvsttgi lagvkmshaa tsalcrsvkl qcelypsrqi
     1201 aicldpycgl gfalwclcsv ysghqsilvp pleletnpsl wlsavsqfkv rvtfcsysvm
     1261 emctkalgsq tealrlrsvn lscvrtcmvv aeerpritlt qsfskifkdl glssravstt
     1321 fgcrvnvaic lqgtsgpdpt tvyldmralr hdrvrlverg sphslpltes gkilpgvkvi
     1381 iantetkgpl gdshlgeiwv ssphnatgyy tvygeealha dhfstrlsfg dtqtvwartg
     1441 ylgflrrtel tdasgerhda lyvvgsldet lelrgmryhp idietsvirs hksiaecavf
     1501 twtnllvvvv elegseqeal dlvalvtnvv leehylivgv vvvvdpgvip insrgekqrm
     1561 hlrdgfladq ldpiyvaynm
//
LOCUS       XP_026128382            1551 aa            linear   VRT 18-JUN-2025
DEFINITION  disco-interacting protein 2 homolog A isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128382
VERSION     XP_026128382.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272597.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1551
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1551
                     /product="disco-interacting protein 2 homolog A isoform
                     X3"
                     /calculated_mol_wt=169590
     Region          20..94
                     /region_name="DMAP_binding"
                     /note="DMAP1-binding Domain; pfam06464"
                     /db_xref="CDD:368923"
     Region          332..908
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(493,496..501,503..504)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(496,616..617,675..680,773,785,788,799,888)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(496,537..538,588,590..591,594,616..617,635..640,773,
                     785,788,796..799,869)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(537,590..591,594,616,796..798,856,869)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Region          983..1547
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(1132,1135..1140,1142..1143)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(1135,1261..1262,1316..1321,1412,1434,1437,1448,1527)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(1135,1176..1177,1227,1229..1230,1233,1261..1262,
                     1279..1284,1412,1434,1437,1445..1448,1508)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(1176,1229..1230,1233,1261,1445..1447,1495,1508)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     CDS             1..1551
                     /gene="dip2a"
                     /coded_by="XM_026272597.1:371..5026"
                     /db_xref="GeneID:113109065"
ORIGIN      
        1 maersstgll mmmldpspai amtlpaevre klaelelels egditqkgye kkrgkllapy
       61 ipqiqdlhte avqaalakyk erkmpmpskr rsvlvqssve actppdtssa sedegslrrq
      121 griassspyq ahpsvehwfn rviqgsstss sasstsshpg grphhatntt sasaatvlad
      181 lmahtqldnh sappdvtgls ersvhaerpq vasmrglprg ythtsvmeta dgtdkgdgea
      241 ldgvpvnsrv sskiqqllnt lkrpkrpplr effvddfeel ldvqhpdpnq pkpeggemrp
      301 lngdplgvvt nwppsllasl qrwgttqpks pcltaldnag kpiytltygk lwtqsqklay
      361 tllnklstrn epllrpgdrv alvfpnndpv mfmvafyacl laelvpvpie vpltrkdags
      421 qqvgfllgsc gvtlalttda cqkglpkaqt gevvtfkgwp rllwfvtdgk hvakppkdwh
      481 ppirdacnei ayieyktske gstmgitvsh samlahchal tqacgytege iitnvldfkr
      541 daglwhgvlt svmnrmhvis ipyslmkvnp lswiqkvhty karvavvksr dmhwsllaqr
      601 dqrdislssl rmlivadgan pwsisscdaf lnvfqarglr pevicpcass seamtvairr
      661 ppemgvpppg kavlsmsgls ygvirvdtee klsvltvqdv gqvmpgalvc virlegtpyl
      721 crtdevgeic vsssstgisy yglpgmtknv fetipvtssg apisdrpftr tsllgfigpd
      781 nlvfvvgkmd glmvvsgrrh naddvvatal avepmkfvyr griavfslsv lhderivvva
      841 eqrpdaseed sfqwmsrvlq aidsihqvgv yclalvpant lpkaplggih isetkqrfle
      901 galhpcnvlm cphtcvtnlp kprqkqpgte vgpasmivgn lvagkriaqa cgrdvsqled
      961 ndqflymqdv lqwraqatpd hplflllnak gtvantascv qlhkraerva valmergrln
     1021 tgdhvalvyp pgvdliatfy gclyagcvpv tvrpphpqnl tttlptvkmi vevsksvcil
     1081 ttqaimkllk skeaaaavdi ktwplildtd dlprkripqi ykpptpemla yldfsvsttg
     1141 ilagvkmsha atsalcrsvk lqcelypsrq iaicldpycg lgfalwclcs vysghqsilv
     1201 ppleletnps lwlsavsqfk vrvtfcsysv memctkalgs qtealrlrsv nlscvrtcmv
     1261 vaeerpritl tqsfskifkd lglssravst tfgcrvnvai clqgtsgpdp ttvyldmral
     1321 rhdrvrlver gsphslplte sgkilpgvkv iiantetkgp lgdshlgeiw vssphnatgy
     1381 ytvygeealh adhfstrlsf gdtqtvwart gylgflrrte ltdasgerhd alyvvgslde
     1441 tlelrgmryh pidietsvir shksiaecav ftwtnllvvv velegseqea ldlvalvtnv
     1501 vleehylivg vvvvvdpgvi pinsrgekqr mhlrdgflad qldpiyvayn m
//
LOCUS       XP_026128383            1536 aa            linear   VRT 18-JUN-2025
DEFINITION  disco-interacting protein 2 homolog A isoform X4 [Carassius
            auratus].
ACCESSION   XP_026128383
VERSION     XP_026128383.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272598.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1536
                     /product="disco-interacting protein 2 homolog A isoform
                     X4"
                     /calculated_mol_wt=168191
     Region          20..134
                     /region_name="DMAP_binding"
                     /note="DMAP1-binding Domain; pfam06464"
                     /db_xref="CDD:368923"
     Region          317..893
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(478,481..486,488..489)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(481,601..602,660..665,758,770,773,784,873)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(481,522..523,573,575..576,579,601..602,620..625,758,
                     770,773,781..784,854)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(522,575..576,579,601,781..783,841,854)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Region          968..1532
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(1117,1120..1125,1127..1128)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(1120,1246..1247,1301..1306,1397,1419,1422,1433,1512)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(1120,1161..1162,1212,1214..1215,1218,1246..1247,
                     1264..1269,1397,1419,1422,1430..1433,1493)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(1161,1214..1215,1218,1246,1430..1432,1480,1493)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     CDS             1..1536
                     /gene="dip2a"
                     /coded_by="XM_026272598.1:371..4981"
                     /db_xref="GeneID:113109065"
ORIGIN      
        1 maersstgll mmmldpspai amtlpaevre klaelelels egditqkgye kkrgkllapy
       61 ipqiqgvdps lqiehriqts sqvappgskq nkprvansrd ecfrsdlhte avqaalakyk
      121 erkmpmpskr rsvlvqssve actppdtssa sedegslrrq griassspyq ahpsvehwfn
      181 rviqgsstss sasstsshpg grphhatntt sasaatvlad lmahtqlgvp vnsrvsskiq
      241 qllntlkrpk rpplreffvd dfeelldvqh pdpnqpkpeg gemrplngdp lgvvtnwpps
      301 llaslqrwgt tqpkspclta ldnagkpiyt ltygklwtqs qklaytllnk lstrnepllr
      361 pgdrvalvfp nndpvmfmva fyacllaelv pvpievpltr kdagsqqvgf llgscgvtla
      421 lttdacqkgl pkaqtgevvt fkgwprllwf vtdgkhvakp pkdwhppird acneiayiey
      481 ktskegstmg itvshsamla hchaltqacg ytegeiitnv ldfkrdaglw hgvltsvmnr
      541 mhvisipysl mkvnplswiq kvhtykarva vvksrdmhws llaqrdqrdi slsslrmliv
      601 adganpwsis scdaflnvfq arglrpevic pcassseamt vairrppemg vpppgkavls
      661 msglsygvir vdteeklsvl tvqdvgqvmp galvcvirle gtpylcrtde vgeicvssss
      721 tgisyyglpg mtknvfetip vtssgapisd rpftrtsllg figpdnlvfv vgkmdglmvv
      781 sgrrhnaddv vatalavepm kfvyrgriav fslsvlhder ivvvaeqrpd aseedsfqwm
      841 srvlqaidsi hqvgvyclal vpantlpkap lggihisetk qrflegalhp cnvlmcphtc
      901 vtnlpkprqk qpgtevgpas mivgnlvagk riaqacgrdv sqledndqfl ymqdvlqwra
      961 qatpdhplfl llnakgtvan tascvqlhkr aervavalme rgrlntgdhv alvyppgvdl
     1021 iatfygclya gcvpvtvrpp hpqnltttlp tvkmivevsk svcilttqai mkllkskeaa
     1081 aavdiktwpl ildtddlprk ripqiykppt pemlayldfs vsttgilagv kmshaatsal
     1141 crsvklqcel ypsrqiaicl dpycglgfal wclcsvysgh qsilvpplel etnpslwlsa
     1201 vsqfkvrvtf csysvmemct kalgsqteal rlrsvnlscv rtcmvvaeer pritltqsfs
     1261 kifkdlglss ravsttfgcr vnvaiclqgt sgpdpttvyl dmralrhdrv rlvergsphs
     1321 lpltesgkil pgvkviiant etkgplgdsh lgeiwvssph natgyytvyg eealhadhfs
     1381 trlsfgdtqt vwartgylgf lrrteltdas gerhdalyvv gsldetlelr gmryhpidie
     1441 tsvirshksi aecavftwtn llvvvveleg seqealdlva lvtnvvleeh ylivgvvvvv
     1501 dpgvipinsr gekqrmhlrd gfladqldpi yvaynm
//
LOCUS       XP_026128384            1468 aa            linear   VRT 18-JUN-2025
DEFINITION  disco-interacting protein 2 homolog A isoform X5 [Carassius
            auratus].
ACCESSION   XP_026128384
VERSION     XP_026128384.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272599.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1468
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1468
                     /product="disco-interacting protein 2 homolog A isoform
                     X5"
                     /calculated_mol_wt=160322
     Region          249..825
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(410,413..418,420..421)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(413,533..534,592..597,690,702,705,716,805)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(413,454..455,505,507..508,511,533..534,552..557,690,
                     702,705,713..716,786)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(454,507..508,511,533,713..715,773,786)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Region          900..1464
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(1049,1052..1057,1059..1060)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(1052,1178..1179,1233..1238,1329,1351,1354,1365,1444)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(1052,1093..1094,1144,1146..1147,1150,1178..1179,
                     1196..1201,1329,1351,1354,1362..1365,1425)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(1093,1146..1147,1150,1178,1362..1364,1412,1425)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     CDS             1..1468
                     /gene="dip2a"
                     /coded_by="XM_026272599.1:683..5089"
                     /db_xref="GeneID:113109065"
ORIGIN      
        1 mpmpskrrsv lvqssveact ppdtssased egslrrqgri assspyqahp svehwfnrvi
       61 qgsstsssas stsshpggrp hhatnttsas aatvladlma htqldnhsap pdvtglsers
      121 vhaerpqvas mrglprgyth tsvmetadgt dkgdgealdg vpvnsrvssk iqqllntlkr
      181 pkrpplreff vddfeelldv qhpdpnqpkp eggemrplng dplgvvtnwp psllaslqrw
      241 gttqpkspcl taldnagkpi ytltygklwt qsqklaytll nklstrnepl lrpgdrvalv
      301 fpnndpvmfm vafyacllae lvpvpievpl trkdagsqqv gfllgscgvt lalttdacqk
      361 glpkaqtgev vtfkgwprll wfvtdgkhva kppkdwhppi rdacneiayi eyktskegst
      421 mgitvshsam lahchaltqa cgytegeiit nvldfkrdag lwhgvltsvm nrmhvisipy
      481 slmkvnplsw iqkvhtykar vavvksrdmh wsllaqrdqr dislsslrml ivadganpws
      541 isscdaflnv fqarglrpev icpcasssea mtvairrppe mgvpppgkav lsmsglsygv
      601 irvdteekls vltvqdvgqv mpgalvcvir legtpylcrt devgeicvss sstgisyygl
      661 pgmtknvfet ipvtssgapi sdrpftrtsl lgfigpdnlv fvvgkmdglm vvsgrrhnad
      721 dvvatalave pmkfvyrgri avfslsvlhd erivvvaeqr pdaseedsfq wmsrvlqaid
      781 sihqvgvycl alvpantlpk aplggihise tkqrflegal hpcnvlmcph tcvtnlpkpr
      841 qkqpgtevgp asmivgnlva gkriaqacgr dvsqledndq flymqdvlqw raqatpdhpl
      901 flllnakgtv antascvqlh kraervaval mergrlntgd hvalvyppgv dliatfygcl
      961 yagcvpvtvr pphpqnlttt lptvkmivev sksvcilttq aimkllkske aaaavdiktw
     1021 plildtddlp rkripqiykp ptpemlayld fsvsttgila gvkmshaats alcrsvklqc
     1081 elypsrqiai cldpycglgf alwclcsvys ghqsilvppl eletnpslwl savsqfkvrv
     1141 tfcsysvmem ctkalgsqte alrlrsvnls cvrtcmvvae erpritltqs fskifkdlgl
     1201 ssravsttfg crvnvaiclq gtsgpdpttv yldmralrhd rvrlvergsp hslpltesgk
     1261 ilpgvkviia ntetkgplgd shlgeiwvss phnatgyytv ygeealhadh fstrlsfgdt
     1321 qtvwartgyl gflrrteltd asgerhdaly vvgsldetle lrgmryhpid ietsvirshk
     1381 siaecavftw tnllvvvvel egseqealdl valvtnvvle ehylivgvvv vvdpgvipin
     1441 srgekqrmhl rdgfladqld piyvaynm
//
LOCUS       XP_026128385            1468 aa            linear   VRT 18-JUN-2025
DEFINITION  disco-interacting protein 2 homolog A isoform X5 [Carassius
            auratus].
ACCESSION   XP_026128385
VERSION     XP_026128385.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272600.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1468
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1468
                     /product="disco-interacting protein 2 homolog A isoform
                     X5"
                     /calculated_mol_wt=160322
     Region          249..825
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(410,413..418,420..421)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(413,533..534,592..597,690,702,705,716,805)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(413,454..455,505,507..508,511,533..534,552..557,690,
                     702,705,713..716,786)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(454,507..508,511,533,713..715,773,786)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Region          900..1464
                     /region_name="Dip2"
                     /note="Disco-interacting protein 2 (Dip2); cd05905"
                     /db_xref="CDD:341231"
     Site            order(1049,1052..1057,1059..1060)
                     /site_type="other"
                     /note="putative acyl-activating enzyme (AAE) consensus
                     motif"
                     /db_xref="CDD:341231"
     Site            order(1052,1178..1179,1233..1238,1329,1351,1354,1365,1444)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341231"
     Site            order(1052,1093..1094,1144,1146..1147,1150,1178..1179,
                     1196..1201,1329,1351,1354,1362..1365,1425)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341231"
     Site            order(1093,1146..1147,1150,1178,1362..1364,1412,1425)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341231"
     CDS             1..1468
                     /gene="dip2a"
                     /coded_by="XM_026272600.1:563..4969"
                     /db_xref="GeneID:113109065"
ORIGIN      
        1 mpmpskrrsv lvqssveact ppdtssased egslrrqgri assspyqahp svehwfnrvi
       61 qgsstsssas stsshpggrp hhatnttsas aatvladlma htqldnhsap pdvtglsers
      121 vhaerpqvas mrglprgyth tsvmetadgt dkgdgealdg vpvnsrvssk iqqllntlkr
      181 pkrpplreff vddfeelldv qhpdpnqpkp eggemrplng dplgvvtnwp psllaslqrw
      241 gttqpkspcl taldnagkpi ytltygklwt qsqklaytll nklstrnepl lrpgdrvalv
      301 fpnndpvmfm vafyacllae lvpvpievpl trkdagsqqv gfllgscgvt lalttdacqk
      361 glpkaqtgev vtfkgwprll wfvtdgkhva kppkdwhppi rdacneiayi eyktskegst
      421 mgitvshsam lahchaltqa cgytegeiit nvldfkrdag lwhgvltsvm nrmhvisipy
      481 slmkvnplsw iqkvhtykar vavvksrdmh wsllaqrdqr dislsslrml ivadganpws
      541 isscdaflnv fqarglrpev icpcasssea mtvairrppe mgvpppgkav lsmsglsygv
      601 irvdteekls vltvqdvgqv mpgalvcvir legtpylcrt devgeicvss sstgisyygl
      661 pgmtknvfet ipvtssgapi sdrpftrtsl lgfigpdnlv fvvgkmdglm vvsgrrhnad
      721 dvvatalave pmkfvyrgri avfslsvlhd erivvvaeqr pdaseedsfq wmsrvlqaid
      781 sihqvgvycl alvpantlpk aplggihise tkqrflegal hpcnvlmcph tcvtnlpkpr
      841 qkqpgtevgp asmivgnlva gkriaqacgr dvsqledndq flymqdvlqw raqatpdhpl
      901 flllnakgtv antascvqlh kraervaval mergrlntgd hvalvyppgv dliatfygcl
      961 yagcvpvtvr pphpqnlttt lptvkmivev sksvcilttq aimkllkske aaaavdiktw
     1021 plildtddlp rkripqiykp ptpemlayld fsvsttgila gvkmshaats alcrsvklqc
     1081 elypsrqiai cldpycglgf alwclcsvys ghqsilvppl eletnpslwl savsqfkvrv
     1141 tfcsysvmem ctkalgsqte alrlrsvnls cvrtcmvvae erpritltqs fskifkdlgl
     1201 ssravsttfg crvnvaiclq gtsgpdpttv yldmralrhd rvrlvergsp hslpltesgk
     1261 ilpgvkviia ntetkgplgd shlgeiwvss phnatgyytv ygeealhadh fstrlsfgdt
     1321 qtvwartgyl gflrrteltd asgerhdaly vvgsldetle lrgmryhpid ietsvirshk
     1381 siaecavftw tnllvvvvel egseqealdl valvtnvvle ehylivgvvv vvdpgvipin
     1441 srgekqrmhl rdgfladqld piyvaynm
//
LOCUS       XP_026128386             476 aa            linear   VRT 18-JUN-2025
DEFINITION  CASP8 and FADD-like apoptosis regulator isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128386
VERSION     XP_026128386.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272601.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..476
                     /product="CASP8 and FADD-like apoptosis regulator isoform
                     X1"
                     /calculated_mol_wt=53529
     Region          5..82
                     /region_name="DD"
                     /note="Death Domain Superfamily of protein-protein
                     interaction domains; cl14633"
                     /db_xref="CDD:472698"
     Region          94..174
                     /region_name="DED"
                     /note="Death effector domain; pfam01335"
                     /db_xref="CDD:460163"
     Region          241..476
                     /region_name="CASc"
                     /note="Caspase, interleukin-1 beta converting enzyme (ICE)
                     homologues; Cysteine-dependent aspartate-directed
                     proteases that mediate programmed cell death (apoptosis).
                     Caspases are synthesized as inactive zymogens and
                     activated by proteolysis of the peptide...; cl00042"
                     /db_xref="CDD:444667"
     Site            order(312,357)
                     /site_type="active"
                     /db_xref="CDD:237997"
     Site            order(363,395..396,403,406,409,431,440,446,460,465..466,
                     468,471..472)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:237997"
     Site            order(364,394)
                     /site_type="active"
                     /note="proteolytic cleavage site [active]"
                     /db_xref="CDD:237997"
     CDS             1..476
                     /gene="cflarb"
                     /coded_by="XM_026272601.1:57..1487"
                     /db_xref="GeneID:113109066"
ORIGIN      
        1 msslyhtisq itdelstdec krisylcgal dtdkfsadpr gmlqsvlcqm rmdyvflmel
       61 ilkikrydll revlstnkst vegllknshs vseyrvlmad vsedmdtenl kslafllrgt
      121 lpkhklenvq sfldivvele kldqlssekm dliehclrsi hradlakkis hyqqtalmtk
      181 qgssppdrlt fctapspsss fsvssasrni wpvsklcekp tavkkkllgt ssycqqleev
      241 ysmqrdrrgv cliidcvgte adeleqifka lhfcvvthkl lsvrdvqsal revahqqghy
      301 rasafvccvi srsrssdlla tdshgpglnl dtvrrlftsd scpglagkpk lffiqsyees
      361 eaqscagcmg cgdeeagele tdapgllcck rtvpvdadif wshcwtkgqq levpnhrsvy
      421 lralrasltq gqkrrthlvd lhmavnravy ehnhkspess yflnlrhtlr ktvyls
//
LOCUS       XP_026128387             476 aa            linear   VRT 18-JUN-2025
DEFINITION  CASP8 and FADD-like apoptosis regulator isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128387
VERSION     XP_026128387.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272602.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..476
                     /product="CASP8 and FADD-like apoptosis regulator isoform
                     X1"
                     /calculated_mol_wt=53529
     Region          5..82
                     /region_name="DD"
                     /note="Death Domain Superfamily of protein-protein
                     interaction domains; cl14633"
                     /db_xref="CDD:472698"
     Region          94..174
                     /region_name="DED"
                     /note="Death effector domain; pfam01335"
                     /db_xref="CDD:460163"
     Region          241..476
                     /region_name="CASc"
                     /note="Caspase, interleukin-1 beta converting enzyme (ICE)
                     homologues; Cysteine-dependent aspartate-directed
                     proteases that mediate programmed cell death (apoptosis).
                     Caspases are synthesized as inactive zymogens and
                     activated by proteolysis of the peptide...; cl00042"
                     /db_xref="CDD:444667"
     Site            order(312,357)
                     /site_type="active"
                     /db_xref="CDD:237997"
     Site            order(363,395..396,403,406,409,431,440,446,460,465..466,
                     468,471..472)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:237997"
     Site            order(364,394)
                     /site_type="active"
                     /note="proteolytic cleavage site [active]"
                     /db_xref="CDD:237997"
     CDS             1..476
                     /gene="cflarb"
                     /coded_by="XM_026272602.1:57..1487"
                     /db_xref="GeneID:113109066"
ORIGIN      
        1 msslyhtisq itdelstdec krisylcgal dtdkfsadpr gmlqsvlcqm rmdyvflmel
       61 ilkikrydll revlstnkst vegllknshs vseyrvlmad vsedmdtenl kslafllrgt
      121 lpkhklenvq sfldivvele kldqlssekm dliehclrsi hradlakkis hyqqtalmtk
      181 qgssppdrlt fctapspsss fsvssasrni wpvsklcekp tavkkkllgt ssycqqleev
      241 ysmqrdrrgv cliidcvgte adeleqifka lhfcvvthkl lsvrdvqsal revahqqghy
      301 rasafvccvi srsrssdlla tdshgpglnl dtvrrlftsd scpglagkpk lffiqsyees
      361 eaqscagcmg cgdeeagele tdapgllcck rtvpvdadif wshcwtkgqq levpnhrsvy
      421 lralrasltq gqkrrthlvd lhmavnravy ehnhkspess yflnlrhtlr ktvyls
//
LOCUS       XP_026128388             475 aa            linear   VRT 18-JUN-2025
DEFINITION  CASP8 and FADD-like apoptosis regulator isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128388
VERSION     XP_026128388.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272603.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..475
                     /product="CASP8 and FADD-like apoptosis regulator isoform
                     X2"
                     /calculated_mol_wt=53400
     Region          5..82
                     /region_name="DD"
                     /note="Death Domain Superfamily of protein-protein
                     interaction domains; cl14633"
                     /db_xref="CDD:472698"
     Region          94..174
                     /region_name="DED"
                     /note="Death effector domain; pfam01335"
                     /db_xref="CDD:460163"
     Region          240..475
                     /region_name="CASc"
                     /note="Caspase, interleukin-1 beta converting enzyme (ICE)
                     homologues; Cysteine-dependent aspartate-directed
                     proteases that mediate programmed cell death (apoptosis).
                     Caspases are synthesized as inactive zymogens and
                     activated by proteolysis of the peptide...; cl00042"
                     /db_xref="CDD:444667"
     Site            order(311,356)
                     /site_type="active"
                     /db_xref="CDD:237997"
     Site            order(362,394..395,402,405,408,430,439,445,459,464..465,
                     467,470..471)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:237997"
     Site            order(363,393)
                     /site_type="active"
                     /note="proteolytic cleavage site [active]"
                     /db_xref="CDD:237997"
     CDS             1..475
                     /gene="cflarb"
                     /coded_by="XM_026272603.1:57..1484"
                     /db_xref="GeneID:113109066"
ORIGIN      
        1 msslyhtisq itdelstdec krisylcgal dtdkfsadpr gmlqsvlcqm rmdyvflmel
       61 ilkikrydll revlstnkst vegllknshs vseyrvlmad vsedmdtenl kslafllrgt
      121 lpkhklenvq sfldivvele kldqlssekm dliehclrsi hradlakkis hyqqtalmtk
      181 qgssppdrlt fctapspsss fsvssasrni wpvsklcekp tavkkkllgt ssycqleevy
      241 smqrdrrgvc liidcvgtea deleqifkal hfcvvthkll svrdvqsalr evahqqghyr
      301 asafvccvis rsrssdllat dshgpglnld tvrrlftsds cpglagkpkl ffiqsyeese
      361 aqscagcmgc gdeeagelet dapgllcckr tvpvdadifw shcwtkgqql evpnhrsvyl
      421 ralrasltqg qkrrthlvdl hmavnravye hnhkspessy flnlrhtlrk tvyls
//
LOCUS       XP_026128389             933 aa            linear   VRT 18-JUN-2025
DEFINITION  ubiquitin carboxyl-terminal hydrolase 37-like [Carassius auratus].
ACCESSION   XP_026128389
VERSION     XP_026128389.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272604.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..933
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..933
                     /product="ubiquitin carboxyl-terminal hydrolase 37-like"
                     /calculated_mol_wt=104529
     Region          8..110
                     /region_name="UCH_N"
                     /note="N-terminal of ubiquitin carboxyl-terminal hydrolase
                     37; pfam16674"
                     /db_xref="CDD:465227"
     Region          323..593
                     /region_name="UCH"
                     /note="Ubiquitin carboxyl-terminal hydrolase; pfam00443"
                     /db_xref="CDD:425685"
     CDS             1..933
                     /gene="LOC113109068"
                     /coded_by="XM_026272604.1:217..3018"
                     /db_xref="GeneID:113109068"
ORIGIN      
        1 msvavprmts ggavririrc gelgttkwke gvfeiherdn kinllvkfns ggtprmfqln
       61 hnvkqvswyq trgpnrmtlt lkdssvvmmd klsllvakkm kdylemvrlg kpavlktnqg
      121 sasfglvlgn rtaqidsgls psekqstprr psldsredst prkplgspsr atstpgrngl
      181 sdnrsekrkr lmnsdgdmte dypkendsss nnkaitdssr kfllsckekl kqseenrana
      241 phtpaplqpt sfygsrtgtk dysqihsvld rssstgqcps akrslmlpnh stpfkkvrpv
      301 ldyggwnkpr psalaqpqpp lqgfsnlgnt cymnailqsl fslpsfsndl lkqgipwkrv
      361 pinallrrfa hllakkdisp pevkkdllrr vknaisstae rfsgymqnda heflsqcldq
      421 lkedvekink swknepsage eppsprlaee vdtsriytcp vtvnmefevq htitckscge
      481 vvtkreqfnd lsidlprrrk tlplrsiqds ldlffrmeei eyscekcsgk aatvshkfsr
      541 lprvlilhlk rysynsqlsl nsklgqqvli pkyltllshc tdatrpplsl gwsaqtavsr
      601 tlkisqsvns stlrkasqkp essgsmlcds dseeelvrkv grkhseddrt eevqhnaqve
      661 hselnavndd emlaavless prntslsgcp ddvptsspdt gfgdadgqdl tphlelldae
      721 kqpadalesl dltmdenken qtpegvqgel dwvqqysldq ereeqelqqa laqslqehea
      781 remredddlk ratelslqef nnslpellcs dddsgnedgl dmeyseaete elkknaetge
      841 lpnsfrlisv vshigsssss ghyisdvydm rkqswltynd ldvsrtqest vqrdrdrsgy
      901 iffymhkdvf eelselekag gnsdagrtvl qpl
//
LOCUS       XP_026128391             226 aa            linear   VRT 18-JUN-2025
DEFINITION  insulin-induced gene 2 protein-like [Carassius auratus].
ACCESSION   XP_026128391
VERSION     XP_026128391.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272606.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..226
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..226
                     /product="insulin-induced gene 2 protein-like"
                     /calculated_mol_wt=24841
     Region          31..212
                     /region_name="INSIG"
                     /note="Insulin-induced protein (INSIG); pfam07281"
                     /db_xref="CDD:462131"
     CDS             1..226
                     /gene="LOC113109069"
                     /coded_by="XM_026272606.1:320..1000"
                     /db_xref="GeneID:113109069"
ORIGIN      
        1 maevsslsgg almhrgpyis vitnrtmnll iraamlfmvg vflalvlnll qvqrnvtlfp
       61 pdvissvfss awwvppccgt aaaligllyp cmdrrlgeph qlkrewsnvm rcvavfvgin
      121 hasakvdfan nvqlsltlga lsvglwwtfd rsrsgfglgv iiallatlat qllvyngvfq
      181 ytspdflyir swlpciffag vitvgnigrq lalyeykvsq ekphqd
//
LOCUS       XP_026128392             226 aa            linear   VRT 18-JUN-2025
DEFINITION  insulin-induced gene 2 protein-like [Carassius auratus].
ACCESSION   XP_026128392
VERSION     XP_026128392.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272607.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..226
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..226
                     /product="insulin-induced gene 2 protein-like"
                     /calculated_mol_wt=24841
     Region          31..212
                     /region_name="INSIG"
                     /note="Insulin-induced protein (INSIG); pfam07281"
                     /db_xref="CDD:462131"
     CDS             1..226
                     /gene="LOC113109069"
                     /coded_by="XM_026272607.1:186..866"
                     /db_xref="GeneID:113109069"
ORIGIN      
        1 maevsslsgg almhrgpyis vitnrtmnll iraamlfmvg vflalvlnll qvqrnvtlfp
       61 pdvissvfss awwvppccgt aaaligllyp cmdrrlgeph qlkrewsnvm rcvavfvgin
      121 hasakvdfan nvqlsltlga lsvglwwtfd rsrsgfglgv iiallatlat qllvyngvfq
      181 ytspdflyir swlpciffag vitvgnigrq lalyeykvsq ekphqd
//
LOCUS       XP_026128393             165 aa            linear   VRT 18-JUN-2025
DEFINITION  endoribonuclease YbeY isoform X1 [Carassius auratus].
ACCESSION   XP_026128393
VERSION     XP_026128393.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272608.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..165
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..165
                     /product="endoribonuclease YbeY isoform X1"
                     /calculated_mol_wt=19296
     Region          35..150
                     /region_name="TIGR00043"
                     /note="rRNA maturation RNase YbeY"
                     /db_xref="CDD:272871"
     CDS             1..165
                     /gene="ybey"
                     /coded_by="XM_026272608.1:219..716"
                     /db_xref="GeneID:113109070"
ORIGIN      
        1 mgvvlrnlqs vvplrrarlr rdvevlrhif gvqrfdlgii cvdnrriqhi nnlyrknnqp
       61 tdvlsfpfye dlrpgkipca lqrdeynlgd iflgveyvkh rcketsqdlh ealtvvtahg
      121 ichllgyrhe teeewiemqq kesyilsefn rltgshlepl tkrct
//
LOCUS       XP_026128394             121 aa            linear   VRT 18-JUN-2025
DEFINITION  endoribonuclease YbeY isoform X2 [Carassius auratus].
ACCESSION   XP_026128394
VERSION     XP_026128394.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272609.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..121
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..121
                     /product="endoribonuclease YbeY isoform X2"
                     /calculated_mol_wt=14241
     Region          35..106
                     /region_name="PRK13963"
                     /note="rRNA maturation RNase YbeY; cl46897"
                     /db_xref="CDD:481237"
     CDS             1..121
                     /gene="ybey"
                     /coded_by="XM_026272609.1:227..592"
                     /db_xref="GeneID:113109070"
ORIGIN      
        1 mgvvlrnlqs vvplrrarlr rdvevlrhif gvqrfdlgii cvdnrriqhi nnlyrknnqp
       61 tdvlsfpfye vvtahgichl lgyrheteee wiemqqkesy ilsefnrltg shlepltkrc
      121 t
//
LOCUS       XP_026128395             139 aa            linear   VRT 18-JUN-2025
DEFINITION  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like
            isoform X1 [Carassius auratus].
ACCESSION   XP_026128395
VERSION     XP_026128395.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272610.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..139
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..139
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 3-like isoform X1"
                     /calculated_mol_wt=15663
     Region          85..139
                     /region_name="NDUF_B12"
                     /note="NADH-ubiquinone oxidoreductase B12 subunit family;
                     pfam08122"
                     /db_xref="CDD:462364"
     CDS             1..139
                     /gene="LOC113109071"
                     /coded_by="XM_026272610.1:30..449"
                     /db_xref="GeneID:113109071"
ORIGIN      
        1 mtidtlhked ktlkiiakke avsltelpgl iarscwrslc ynrkavvmgg dhghgklsmp
       61 dykvwkwegt pleatqqrla rrglrdpwar neawrytgsf gvpvtfrnvl lrgfktgfaa
      121 favalaveya ffppkkseh
//
LOCUS       XP_026128396             138 aa            linear   VRT 18-JUN-2025
DEFINITION  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like
            isoform X2 [Carassius auratus].
ACCESSION   XP_026128396
VERSION     XP_026128396.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272611.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..138
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..138
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 3-like isoform X2"
                     /calculated_mol_wt=15592
     Region          84..138
                     /region_name="NDUF_B12"
                     /note="NADH-ubiquinone oxidoreductase B12 subunit family;
                     pfam08122"
                     /db_xref="CDD:462364"
     CDS             1..138
                     /gene="LOC113109071"
                     /coded_by="XM_026272611.1:30..446"
                     /db_xref="GeneID:113109071"
ORIGIN      
        1 mtidtlhked ktlkiiakke avsltelpgl iarscwrslc ynrkvvmggd hghgklsmpd
       61 ykvwkwegtp leatqqrlar rglrdpwarn eawrytgsfg vpvtfrnvll rgfktgfaaf
      121 avalaveyaf fppkkseh
//
LOCUS       XP_026128397              92 aa            linear   VRT 18-JUN-2025
DEFINITION  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like
            isoform X3 [Carassius auratus].
ACCESSION   XP_026128397
VERSION     XP_026128397.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272612.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..92
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..92
                     /product="NADH dehydrogenase [ubiquinone] 1 beta
                     subcomplex subunit 3-like isoform X3"
                     /calculated_mol_wt=10337
     Region          38..92
                     /region_name="NDUF_B12"
                     /note="NADH-ubiquinone oxidoreductase B12 subunit family;
                     pfam08122"
                     /db_xref="CDD:462364"
     CDS             1..92
                     /gene="LOC113109071"
                     /coded_by="XM_026272612.1:98..376"
                     /db_xref="GeneID:113109071"
ORIGIN      
        1 mggdhghgkl smpdykvwkw egtpleatqq rlarrglrdp warneawryt gsfgvpvtfr
       61 nvllrgfktg faafavalav eyaffppkks eh
//
LOCUS       XP_026128398             821 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109072 [Carassius auratus].
ACCESSION   XP_026128398
VERSION     XP_026128398.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272613.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..821
                     /product="uncharacterized protein LOC113109072"
                     /calculated_mol_wt=91170
     Region          470..819
                     /region_name="HECTc"
                     /note="HECT domain; C-terminal catalytic domain of a
                     subclass of Ubiquitin-protein ligase (E3). It binds
                     specific ubiquitin-conjugating enzymes (E2), accepts
                     ubiquitin from E2, transfers ubiquitin to substrate lysine
                     side chains, and transfers additional...; cl27008"
                     /db_xref="CDD:474882"
     Site            order(476,510,521,575,753,783..784,787..791,811,818)
                     /site_type="active"
                     /note="catalytic cleft [active]"
                     /db_xref="CDD:238033"
     CDS             1..821
                     /gene="LOC113109072"
                     /coded_by="XM_026272613.1:709..3174"
                     /db_xref="GeneID:113109072"
ORIGIN      
        1 mdrdrtteai nilrnvlasp tiirsiansv essvspsaqm qseteselrt lfrpstsgiq
       61 sinnrqtmpt ssggevqgpr yqtrqqygnw qsrcrkrpkt qyhrtfnkdv illtspddna
      121 vvkqknkqhl heighilnaf efdkswdsmt vlrkikeafk ekvppdvsle ilmgcgnkli
      181 tpmlskgqel ngslilkvfr lkalyvkpsr plllaetdss ddscfevdmp gervyqsega
      241 vpeenvttdl ndqsstqnmi svhsitfqss trdqsptraq fspsfirdqs sassigvqss
      301 trvqsptraq fstssigaqs sassigvqss trvqsptraq fstssigaqs sassigvqss
      361 trvqsptraq fstssigaqs sasgqpytrq nspahcwhnd qsfrsaswdg dyntylslir
      421 aasedeeede dlscaimasi edqiippdve ipikqileel atkinwnqtc kfninrasvl
      481 dgavrgftrl synpnnrmvi kfsddkgkye eaidlggprr eflrlllval mqssmfegke
      541 dslnlaldsq airedryfia gravavslvh ggpapgclsk tlfdslvqgp dmcipvlddv
      601 adfelynkik kvseattlee lqhstvpimd yianagclrp lrsiadrdrl vedllmfqvv
      661 nrvrgpferf rdglktlgvl akvqkhpeaf rsvlchqpnq ltadimddlf eiqwsengsn
      721 kranenrvia fwrdylqdme eegsqrlgav lafatgsdqv ppigfhppps iafhhdtetp
      781 qrfpvantci nclrlplyst ygafksnmef ainntqgfgk e
//
LOCUS       XP_026128400             507 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109073 [Carassius auratus].
ACCESSION   XP_026128400
VERSION     XP_026128400.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272615.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..507
                     /product="uncharacterized protein LOC113109073"
                     /calculated_mol_wt=58953
     Region          159..344
                     /region_name="Tra5"
                     /note="Transposase InsO and inactivated derivatives
                     [Mobilome: prophages, transposons]; COG2801"
                     /db_xref="CDD:442053"
     CDS             1..507
                     /gene="LOC113109073"
                     /coded_by="XM_026272615.1:14..1537"
                     /db_xref="GeneID:113109073"
ORIGIN      
        1 mffrvtliav tfvsalfaga scneddivdf fnsvlqcltr iqqepretly rdldnharti
       61 nsllsvvryd qnaetreciv iletlyrtlh qithpldigr pagaglgpvp pptyitghrg
      121 rprydisyeq lchclrlgfn wqgiasllgi drrtlfqhrq rleirplefa elsnyelntl
      181 vrqilqrtpn agetyilgsl rsrsiriqrw rvrqclheld pigrslrrrr avrrriysvq
      241 tpnqlwhidg nhklvrwrlv fhgcvdgfsr tiiyldclnn nrassvlslf qegvqnfglp
      301 srvrcdhgme nievarymln rrglnrgsvi tgrsvhnqri erlwaelnrv vsyyysdlft
      361 fmeeqcilds lcelhvfclh fiylpriqra vrefrdmwnn hglstergqt plqlwhrgiv
      421 shiginntai sgvlnneehv dinenrpepe lqtrnnvivp eniycpndst laniletfnp
      481 lqndgnhgid lflalvqlle rqqdrtq
//
LOCUS       XP_026128401             246 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein engrailed-1a isoform X1 [Carassius auratus].
ACCESSION   XP_026128401
VERSION     XP_026128401.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272616.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..246
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..246
                     /product="homeobox protein engrailed-1a isoform X1"
                     /calculated_mol_wt=27269
     Region          159..215
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     Region          216..245
                     /region_name="Engrail_1_C_sig"
                     /note="Engrailed homeobox C-terminal signature domain;
                     pfam10525"
                     /db_xref="CDD:431338"
     CDS             1..246
                     /gene="en1a"
                     /coded_by="XM_026272616.1:3272..4012"
                     /db_xref="GeneID:113109075"
ORIGIN      
        1 meeqrgqsed dslpsppllp lqaahhahtt tnffidnilr pdfgcrrehc ptvpgtlcpd
       61 sscsadsvss sasstvsspa srrhsktdrg eaaksglvsa spvalnssge tsspskdthq
      121 llwpawvyct rysdrpssvs tqgprtrklk kkknesedkr prtaftaeql qrlkaefqas
      181 ryiteqrrqa lardlklnes qikiwfqnkr akikkatgfk nglamqlmah glynhstttv
      241 qeeden
//
LOCUS       XP_026128402             242 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein engrailed-1a isoform X2 [Carassius auratus].
ACCESSION   XP_026128402
VERSION     XP_026128402.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272617.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..242
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..242
                     /product="homeobox protein engrailed-1a isoform X2"
                     /calculated_mol_wt=26854
     Region          155..211
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     Region          212..241
                     /region_name="Engrail_1_C_sig"
                     /note="Engrailed homeobox C-terminal signature domain;
                     pfam10525"
                     /db_xref="CDD:431338"
     CDS             1..242
                     /gene="en1a"
                     /coded_by="XM_026272617.1:3272..4000"
                     /db_xref="GeneID:113109075"
ORIGIN      
        1 meeqrgqsed dslpsppllp lqaahhahtt tnffidnilr pdfgcrrehc ptvpgtlcpd
       61 sscsadsvss sasstvsspa srrhsktdrg eaaksglvsa spvalnssge tsspskdthq
      121 llwpawvyct rysdrpssgp rtrklkkkkn esedkrprta ftaeqlqrlk aefqasryit
      181 eqrrqalard lklnesqiki wfqnkrakik katgfkngla mqlmahglyn hstttvqeed
      241 en
//
LOCUS       XP_026128404             456 aa            linear   VRT 18-JUN-2025
DEFINITION  macrophage receptor MARCO [Carassius auratus].
ACCESSION   XP_026128404
VERSION     XP_026128404.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272619.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..456
                     /product="macrophage receptor MARCO"
                     /calculated_mol_wt=46583
     Region          <186..>357
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          361..455
                     /region_name="SR"
                     /note="Scavenger receptor Cys-rich; smart00202"
                     /db_xref="CDD:214555"
     CDS             1..456
                     /gene="LOC113109077"
                     /coded_by="XM_026272619.1:59..1429"
                     /db_xref="GeneID:113109077"
ORIGIN      
        1 metnvdaleg kasvfshanp lydntmklye aerydfqhse pktkkpakkr ycfpvlvlff
       61 lmligmnsfl tykvftleaw vhlhcksada kteelmsaeg fklgssssdq eclsdlcgnd
      121 gtleelrtql nqlnistqra mvcppgpsgp pgrpglqgpp gipgipgqkg dtgskgpvge
      181 agapglkgqr gdqglagerg pagmtgppgi pglkgdtgar giiglpgtdg rrgadgnpgi
      241 qgtpglrgpp glkgdpgakg ergdkgssgs sgsrgltgpt glqgppgekg spgpkgdtgv
      301 glpgrpgqqg qkgsqglsgv pgprgptgek gskgdsglrg pqglkgekgd vgprgappav
      361 vrlvgtssrg rievfhenvw gtvcddsfdt adglvvckml gfqratqvft agagtgriwl
      421 devrctgner sifdcphagm gvnncnhged vgvsca
//
LOCUS       XP_026128405             249 aa            linear   VRT 18-JUN-2025
DEFINITION  complement C1q-like protein 2 [Carassius auratus].
ACCESSION   XP_026128405
VERSION     XP_026128405.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272620.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..249
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..249
                     /product="complement C1q-like protein 2"
                     /calculated_mol_wt=26345
     Region          122..246
                     /region_name="C1q"
                     /note="C1q domain; pfam00386"
                     /db_xref="CDD:395310"
     CDS             1..249
                     /gene="LOC113109078"
                     /coded_by="XM_026272620.1:277..1026"
                     /db_xref="GeneID:113109078"
ORIGIN      
        1 mivalviavp llvqtsvvsa hyemmgtcrm icdpynpkps atalevmqdl sviqpsfaqg
       61 trgepgrpgk pgprgppgep gppgprgppg dsgkpgftgi tsgtartetg divpalgnik
      121 iafyvglknp hegyevlrfd dvvtnvgnhy dpttgkftcq vsgiyyftyh vlmrggdgts
      181 mwadlckngq vrasaiaqda dqnydyasns avlhldsgde iyvkldggka hggnnnkyst
      241 fsgfilypd
//
LOCUS       XP_026128406             385 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128406
VERSION     XP_026128406.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272621.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..385
                     /product="serine/threonine-protein kinase pim-3-like
                     isoform X1"
                     /calculated_mol_wt=43017
     Region          107..384
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..385
                     /gene="LOC113109079"
                     /coded_by="XM_026272621.1:60..1217"
                     /db_xref="GeneID:113109079"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lqllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleesl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag tlqyappewf rhhryhagpa tvwsvgvtly
      301 hvlcscfpfr galrvtsksr llfprelstg krqksgpdpg eacgfvflnt vlcvtecrql
      361 irwclsaaas drpslddier hpwlh
//
LOCUS       XP_026128407             359 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128407
VERSION     XP_026128407.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272622.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..359
                     /product="serine/threonine-protein kinase pim-3-like
                     isoform X2"
                     /calculated_mol_wt=40311
     Region          107..358
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..359
                     /gene="LOC113109079"
                     /coded_by="XM_026272622.1:60..1139"
                     /db_xref="GeneID:113109079"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lqllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleesl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag tlqyappewf rhhryhagpa tvwsvgvtly
      301 hvlcscfpfr galrvtsksr llfprelste crqlirwcls aaasdrpsld dierhpwlh
//
LOCUS       XP_026128408             359 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like [Carassius auratus].
ACCESSION   XP_026128408
VERSION     XP_026128408.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272623.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..359
                     /product="serine/threonine-protein kinase pim-3-like"
                     /calculated_mol_wt=40371
     Region          107..358
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..359
                     /gene="LOC113109080"
                     /coded_by="XM_026272623.1:68..1147"
                     /db_xref="GeneID:113109080"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lkllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleerl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag tlqyappewf rhhryhagpa tvwsvgvtly
      301 nilcscfpfr galrvtsksr llfprelste crqlirwcls aaasdrpsld dierhpwlh
//
LOCUS       XP_026128409             359 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like, partial [Carassius
            auratus].
ACCESSION   XP_026128409
VERSION     XP_026128409.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272624.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on the amino end.
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         <1..359
                     /product="serine/threonine-protein kinase pim-3-like"
     Region          107..358
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..359
                     /gene="LOC113109081"
                     /coded_by="XM_026272624.1:<1..1080"
                     /db_xref="GeneID:113109081"
ORIGIN      
        1 vfdvcniags grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lkllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleerl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag tlqyappewf rhhryhagpa tvwsvgvtly
      301 nilcscfpfr galrvtsksr llfprelste crqlirwcls aaasdrpsld dierhpwlh
//
LOCUS       XP_026128410             344 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like [Carassius auratus].
ACCESSION   XP_026128410
VERSION     XP_026128410.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272625.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..344
                     /product="serine/threonine-protein kinase pim-3-like"
                     /calculated_mol_wt=38658
     Region          92..343
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(95..98,101,103,116,118,156,172..175,219,223..224,
                     226,237..238)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..344
                     /gene="LOC113109082"
                     /coded_by="XM_026272625.1:60..1094"
                     /db_xref="GeneID:113109082"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdglpgy iaplpselav svstdqphrk
       61 rkwqsgsqed ehpspsyrra akrsrreayv kgpllgrggf gsvyagtrrs dglpvaikyv
      121 skrgtqrlrv egqgrlplev almtlvnsap acpnvlklle wfdrprrytm ilerplpcqd
      181 lesfceengr leeslakkvl lqlitalkhc esrgvlhrdv kpenllistd shdiklldfg
      241 cgdllkdsay khfagtlqya ppewfrhhry hagpatvwsv gvtlynilcs cfpfrgalrv
      301 tsksrllfpr elstecrqli rwclsaaasd rpslddierh pwlh
//
LOCUS       XP_026128411             228 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like [Carassius auratus].
ACCESSION   XP_026128411
VERSION     XP_026128411.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272626.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..228
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..228
                     /product="serine/threonine-protein kinase pim-3-like"
                     /calculated_mol_wt=25873
     Region          <1..227
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     CDS             1..228
                     /gene="LOC113109083"
                     /coded_by="XM_026272626.1:82..768"
                     /db_xref="GeneID:113109083"
ORIGIN      
        1 mtlvnsapac pnvlkllewf drprrytmil erplpcqdle sfceengrle erlakkvllq
       61 litalkhces rgvlhrdvkp enllistdsh diklldfgcg dllkdsaykh fagtlqyapp
      121 ewfrhhryha gpatvwsvgv tlynilcscf pfrgalrvts ksrllfarel stgkrqksgp
      181 dpgeacgfvf lntvlcvtec rqlirwclsa aasdrpsldd ierhpwlh
//
LOCUS       XP_026128412             228 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like [Carassius auratus].
ACCESSION   XP_026128412
VERSION     XP_026128412.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272627.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..228
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..228
                     /product="serine/threonine-protein kinase pim-3-like"
                     /calculated_mol_wt=25873
     Region          <1..227
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     CDS             1..228
                     /gene="LOC113109083"
                     /coded_by="XM_026272627.1:82..768"
                     /db_xref="GeneID:113109083"
ORIGIN      
        1 mtlvnsapac pnvlkllewf drprrytmil erplpcqdle sfceengrle erlakkvllq
       61 litalkhces rgvlhrdvkp enllistdsh diklldfgcg dllkdsaykh fagtlqyapp
      121 ewfrhhryha gpatvwsvgv tlynilcscf pfrgalrvts ksrllfarel stgkrqksgp
      181 dpgeacgfvf lntvlcvtec rqlirwclsa aasdrpsldd ierhpwlh
//
LOCUS       XP_026128413             383 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like [Carassius auratus].
ACCESSION   XP_026128413
VERSION     XP_026128413.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272628.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..383
                     /product="serine/threonine-protein kinase pim-3-like"
                     /calculated_mol_wt=42744
     Region          92..314
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(95..98,101,103,116,118,156,172..175,219,223..224,
                     226,237..238)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..383
                     /gene="LOC113109085"
                     /coded_by="XM_026272628.1:84..1235"
                     /db_xref="GeneID:113109085"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdglpgy iaplpselav svstdqphrk
       61 rkwqsgsqed ehpspsyrra akrsrreayv kgpllgrggf gsvyagtrrs dglpvaikyv
      121 skrgtqrlrv egqgrlplev almtlvnsap acpnvlklle wfdrprrytm ilerplpcqd
      181 lesfceengr leeslakkvl lqlitalkhc esrgvlhrdv kpenllistd shdiklldfg
      241 cgdllkdsay khfagtlqya ppewfrhhry hagpatvwsv gvtlynilcs cfpfrgalrv
      301 tsksrllfpr elstgkrqks gpdpgivdwk svgpdvrceg crciyknttg ycghetkgvf
      361 tafcseeela gfcsidcyfr ine
//
LOCUS       XP_026128414             398 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128414
VERSION     XP_026128414.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272629.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..398
                     /product="serine/threonine-protein kinase pim-3-like
                     isoform X1"
                     /calculated_mol_wt=44260
     Region          107..329
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..398
                     /gene="LOC113109086"
                     /coded_by="XM_026272629.1:84..1280"
                     /db_xref="GeneID:113109086"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lkllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleesl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag tlqyappewf rhhryhagpa tvwsvgvtly
      301 nilcscfpfr galrvtsksr llfprelstg krqksgpdpg ivdwksvgpd vrcdgcrciy
      361 knttgycghe tkgvftafcs deelagfcsi dcyfgine
//
LOCUS       XP_026128415             359 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128415
VERSION     XP_026128415.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272630.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..359
                     /product="serine/threonine-protein kinase pim-3-like
                     isoform X2"
                     /calculated_mol_wt=40302
     Region          107..358
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..359
                     /gene="LOC113109086"
                     /coded_by="XM_026272630.1:84..1163"
                     /db_xref="GeneID:113109086"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lkllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleesl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag tlqyappewf rhhryhagpa tvwsvgvtly
      301 nilcscfpfr galrvtsksr llfprelste crqlirwcls aaasdrpsld dierhpwlh
//
LOCUS       XP_026128416             398 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128416
VERSION     XP_026128416.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272631.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..398
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..398
                     /product="serine/threonine-protein kinase pim-3-like
                     isoform X1"
                     /calculated_mol_wt=44360
     Region          107..329
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..398
                     /gene="LOC113109087"
                     /coded_by="XM_026272631.1:41..1237"
                     /db_xref="GeneID:113109087"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lkllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleesl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag tlqyappewf rhhryhagpa tvwsvgvtly
      301 nilcscfpfr galrvtsksr llfprelstg krqksgpdpg ivdwksvgpd vrcdgcrciy
      361 knttgycghe tkgvftafcs deelagfcsi dcyfrine
//
LOCUS       XP_026128417             359 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128417
VERSION     XP_026128417.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272632.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..359
                     /product="serine/threonine-protein kinase pim-3-like
                     isoform X2"
                     /calculated_mol_wt=40302
     Region          107..358
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..359
                     /gene="LOC113109087"
                     /coded_by="XM_026272632.1:41..1120"
                     /db_xref="GeneID:113109087"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lkllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleesl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag tlqyappewf rhhryhagpa tvwsvgvtly
      301 nilcscfpfr galrvtsksr llfprelste crqlirwcls aaasdrpsld dierhpwlh
//
LOCUS       XP_026128418             328 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase pim-3-like isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128418
VERSION     XP_026128418.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272633.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..328
                     /product="serine/threonine-protein kinase pim-3-like
                     isoform X3"
                     /calculated_mol_wt=36433
     Region          107..>270
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(110..113,116,118,131,133,171,187..190,234,238..239,
                     241,252..253)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..328
                     /gene="LOC113109087"
                     /coded_by="XM_026272633.1:41..1027"
                     /db_xref="GeneID:113109087"
ORIGIN      
        1 mahlgerrgs grsrsrsaav sqtddqeler rgsgdgaqep lpnpnqplsq elpgyiaplp
       61 selavsvstd qphrkrkwqs gsqedehpsp syrraakrsr reayvkgpll grggfgsvya
      121 gtrrsdglpv aikyvskrgt qrlrvegqgr lplevalmtl vnsapacpnv lkllewfdrp
      181 rrytmilerp lpcqdlesfc eengrleesl akkvllqlit alkhcesrgv lhrdvkpenl
      241 listdshdik lldfgcgdll kdsaykhfag ivdwksvgpd vrcdgcrciy knttgycghe
      301 tkgvftafcs deelagfcsi dcyfrine
//
LOCUS       XP_026128419             894 aa            linear   VRT 18-JUN-2025
DEFINITION  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [Carassius
            auratus].
ACCESSION   XP_026128419
VERSION     XP_026128419.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272634.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..894
                     /product="dual 3',5'-cyclic-AMP and -GMP phosphodiesterase
                     11A"
                     /calculated_mol_wt=101205
     Region          182..342
                     /region_name="GAF"
                     /note="Domain present in phytochromes and cGMP-specific
                     phosphodiesterases; smart00065"
                     /db_xref="CDD:214500"
     Region          364..530
                     /region_name="GAF"
                     /note="Domain present in phytochromes and cGMP-specific
                     phosphodiesterases; smart00065"
                     /db_xref="CDD:214500"
     Region          625..860
                     /region_name="PDEase_I"
                     /note="3'5'-cyclic nucleotide phosphodiesterase;
                     pfam00233"
                     /db_xref="CDD:459723"
     CDS             1..894
                     /gene="pde11a"
                     /coded_by="XM_026272634.1:199..2883"
                     /db_xref="GeneID:113109089"
ORIGIN      
        1 mtamagsnmv fsdvesflda hpqlledyln rkgkasvvek wmknhhatkt panssaeaek
       61 aanacskdsw asrsdglqrr asqkelrktf arskainanr tydehvnsra qepltsmrrr
      121 allrkasslp pttahilsal lesrvnipqy pstavdykyy lkehnereff lelvkdisnd
      181 ldltslsyki lvfvcimvda drcslflveg psnkktlvsk ffdvhagttv lpslsnsdev
      241 qvpwgkgiig yvaehgetvn ipdayqdhrf sdeidkltgy ktksllcmpi hnsdgevigv
      301 tqainkspng vlfteddekv lqmylpfcgi aisnaqlfaa srkeydrsra llevvndlfe
      361 eqtdlekivr kimhraqtll kcercsvqll ediespvvkf tksfellspk csadmensfk
      421 dsmekssysd wlinnsiael vastglpvni sdayqdprfd aeadqfsgfh irsvlcvpiw
      481 nsnhqiigva qvlnrldgkp fddadqrlfe afvifcglgi nntimydqvk kswakqsval
      541 dvlsyhatcs ktevdkfkaa niplvcelgi dklsfddfsl dvdamvtaal rmfmelgmvq
      601 kfkidyetlc rwlltvrkny rmvlyhnwrh afnvcqcmfs mlttagfqet ltemeilali
      661 vgcichdldh rgtnnafqak tgsalsllyg tsatlehhhf nhavmilqse ghnifsnlss
      721 heygelmqll kqsilatdlt lyfqnrnsff elvnkgeynw nvkehrdmcr smlmtacdlg
      781 avtkpweisr kvaelvtsef feqgdrerse lkltpsaifd rnrkdelpgl qlewidgica
      841 plyetfakln pklqpmvdli kanrakweel hhrhqrsqes sspriadtta sscs
//
LOCUS       XP_026128420             894 aa            linear   VRT 18-JUN-2025
DEFINITION  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [Carassius
            auratus].
ACCESSION   XP_026128420
VERSION     XP_026128420.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272635.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..894
                     /product="dual 3',5'-cyclic-AMP and -GMP phosphodiesterase
                     11A"
                     /calculated_mol_wt=101205
     Region          182..342
                     /region_name="GAF"
                     /note="Domain present in phytochromes and cGMP-specific
                     phosphodiesterases; smart00065"
                     /db_xref="CDD:214500"
     Region          364..530
                     /region_name="GAF"
                     /note="Domain present in phytochromes and cGMP-specific
                     phosphodiesterases; smart00065"
                     /db_xref="CDD:214500"
     Region          625..860
                     /region_name="PDEase_I"
                     /note="3'5'-cyclic nucleotide phosphodiesterase;
                     pfam00233"
                     /db_xref="CDD:459723"
     CDS             1..894
                     /gene="pde11a"
                     /coded_by="XM_026272635.1:199..2883"
                     /db_xref="GeneID:113109089"
ORIGIN      
        1 mtamagsnmv fsdvesflda hpqlledyln rkgkasvvek wmknhhatkt panssaeaek
       61 aanacskdsw asrsdglqrr asqkelrktf arskainanr tydehvnsra qepltsmrrr
      121 allrkasslp pttahilsal lesrvnipqy pstavdykyy lkehnereff lelvkdisnd
      181 ldltslsyki lvfvcimvda drcslflveg psnkktlvsk ffdvhagttv lpslsnsdev
      241 qvpwgkgiig yvaehgetvn ipdayqdhrf sdeidkltgy ktksllcmpi hnsdgevigv
      301 tqainkspng vlfteddekv lqmylpfcgi aisnaqlfaa srkeydrsra llevvndlfe
      361 eqtdlekivr kimhraqtll kcercsvqll ediespvvkf tksfellspk csadmensfk
      421 dsmekssysd wlinnsiael vastglpvni sdayqdprfd aeadqfsgfh irsvlcvpiw
      481 nsnhqiigva qvlnrldgkp fddadqrlfe afvifcglgi nntimydqvk kswakqsval
      541 dvlsyhatcs ktevdkfkaa niplvcelgi dklsfddfsl dvdamvtaal rmfmelgmvq
      601 kfkidyetlc rwlltvrkny rmvlyhnwrh afnvcqcmfs mlttagfqet ltemeilali
      661 vgcichdldh rgtnnafqak tgsalsllyg tsatlehhhf nhavmilqse ghnifsnlss
      721 heygelmqll kqsilatdlt lyfqnrnsff elvnkgeynw nvkehrdmcr smlmtacdlg
      781 avtkpweisr kvaelvtsef feqgdrerse lkltpsaifd rnrkdelpgl qlewidgica
      841 plyetfakln pklqpmvdli kanrakweel hhrhqrsqes sspriadtta sscs
//
LOCUS       XP_026128421             626 aa            linear   VRT 18-JUN-2025
DEFINITION  alkyldihydroxyacetonephosphate synthase, peroxisomal [Carassius
            auratus].
ACCESSION   XP_026128421
VERSION     XP_026128421.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272636.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..626
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..626
                     /product="alkyldihydroxyacetonephosphate synthase,
                     peroxisomal"
                     /calculated_mol_wt=69934
     Region          128..620
                     /region_name="GlcD"
                     /note="FAD/FMN-containing lactate dehydrogenase/glycolate
                     oxidase [Energy production and conversion]; COG0277"
                     /db_xref="CDD:440046"
     CDS             1..626
                     /gene="agps"
                     /coded_by="XM_026272636.1:91..1971"
                     /db_xref="GeneID:113109091"
ORIGIN      
        1 masnssssaq qrlriiaghl qkrpedenag vapqeckaea prsepssttp vprrrqeimk
       61 wngwgysdsr flfnkkgqae ftgkryrlsg lilpslkdwf egtfganlkh rspatpslnl
      121 savappnlnq pfmedlkaag lsvshdpedr vfrahghclh evfalregri grvpdmviwp
      181 schndvekiv elackhnvcl ipygggtsvs salecpreet rsivsldtsq mnrilwidek
      241 nltahveagi igqdlerqln ergyctghep dsmefsslgg wvatrasgmk kniygniedl
      301 vvhikmvtpr gvieksclgp rmstgpdihh filgsegtlg vvtevtlkir pvpeyqkygs
      361 vvfpnfqqgv aclrevarqr capasirlmd neqfqfghal kpqvssmfts fldglkkfyi
      421 tkfkgfdphh lcvatllfeg drgkvlqhek qvydiaakfg glaagedngq rgymltfvia
      481 ylrdlgmdyy vigesfetsv pwdrildlcr nvkerivrec kergvqfppl stcrvtqtyd
      541 agacvyfyfa fnyrglsdpv hiyeqvehaa reeilanggs lshhhgvgkl rkewmkesvs
      601 gvglgvlksv keyvdpqnif gnrnll
//
LOCUS       XP_026128422             589 aa            linear   VRT 18-JUN-2025
DEFINITION  nuclear factor erythroid 2-related factor 2-like isoform X1
            [Carassius auratus].
ACCESSION   XP_026128422
VERSION     XP_026128422.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272637.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..589
                     /product="nuclear factor erythroid 2-related factor 2-like
                     isoform X1"
                     /calculated_mol_wt=66271
     Region          478..545
                     /region_name="bZIP_NFE2-like"
                     /note="Basic leucine zipper (bZIP) domain of Nuclear
                     Factor, Erythroid-derived 2 (NFE2) and similar proteins: a
                     DNA-binding and dimerization domain; cd14720"
                     /db_xref="CDD:269868"
     Region          479..541
                     /region_name="coiled coil"
                     /note="coiled coil [structural motif]"
                     /db_xref="CDD:269868"
     Site            order(487..488,490..492,494..499,501..503)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:269868"
     Site            order(502,505..506,509..510,512..513,516..517,519..520,
                     523..524,526..527,530..531,533..534)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:269868"
     CDS             1..589
                     /gene="LOC113109092"
                     /coded_by="XM_026272637.1:1..1770"
                     /db_xref="GeneID:113109092"
ORIGIN      
        1 mmdielpkmh psqqdmdlid ilwrqdvdlg agrevfdfsy rqkevelrlq rekeeekqqq
       61 rqreqekall aqlqldeetg efvprsaplt qdtvtsaqit qngpfaeldg damsfdecmq
      121 llaetfplde paesappcld tsvppstdlm mppdiptcth npllpgsldq awmellalpe
      181 lqqclnmqmq esldmdgfmk psaeaqdpny sqylpgmdhl slvqtevcpp eyintydgsf
      241 ntmvspnlsq mslnvpdvka efrpeefnem fypemevkvn sgplvpdggn mvsqlaeiss
      301 nppvnpmdlq sfspgsfssg kpepkaefqd sdsglsldss pqvsspgksl ngdgsfgfsd
      361 sdseemddsp ggmesdytei fplvylndaa qgslsskpls dqqemkvknq kiepaeangh
      421 skppftkdkq kkrsetrlsr deqrakalqi pftvdkiinl pvddfnemms khelseaqla
      481 lvrdirrrgk nkvaaqncrk rkmenivgle yeldslkedk erlmkekser ssslremkqq
      541 lstlyhevfs mlrdehgkpf spneyslqht adgtvflvpr lkkilvknn
//
LOCUS       XP_026128423             588 aa            linear   VRT 18-JUN-2025
DEFINITION  nuclear factor erythroid 2-related factor 2-like isoform X2
            [Carassius auratus].
ACCESSION   XP_026128423
VERSION     XP_026128423.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272638.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..588
                     /product="nuclear factor erythroid 2-related factor 2-like
                     isoform X2"
                     /calculated_mol_wt=66143
     Region          477..544
                     /region_name="bZIP_NFE2-like"
                     /note="Basic leucine zipper (bZIP) domain of Nuclear
                     Factor, Erythroid-derived 2 (NFE2) and similar proteins: a
                     DNA-binding and dimerization domain; cd14720"
                     /db_xref="CDD:269868"
     Region          478..540
                     /region_name="coiled coil"
                     /note="coiled coil [structural motif]"
                     /db_xref="CDD:269868"
     Site            order(486..487,489..491,493..498,500..502)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:269868"
     Site            order(501,504..505,508..509,511..512,515..516,518..519,
                     522..523,525..526,529..530,532..533)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:269868"
     CDS             1..588
                     /gene="LOC113109092"
                     /coded_by="XM_026272638.1:167..1933"
                     /db_xref="GeneID:113109092"
ORIGIN      
        1 mmdielpkmh psqqdmdlid ilwrqdvdlg agrevfdfsy rqkevelrlq rekeeekqqq
       61 rqreqekall aqlqldeetg efvprsaplt qdtvtsaqit qngpfaeldg damsfdecmq
      121 llaetfplde paesappcld tsvppstdlm mppdiptcth npllpgsldq awmellalpe
      181 lqclnmqmqe sldmdgfmkp saeaqdpnys qylpgmdhls lvqtevcppe yintydgsfn
      241 tmvspnlsqm slnvpdvkae frpeefnemf ypemevkvns gplvpdggnm vsqlaeissn
      301 ppvnpmdlqs fspgsfssgk pepkaefqds dsglsldssp qvsspgksln gdgsfgfsds
      361 dseemddspg gmesdyteif plvylndaaq gslsskplsd qqemkvknqk iepaeanghs
      421 kppftkdkqk krsetrlsrd eqrakalqip ftvdkiinlp vddfnemmsk helseaqlal
      481 vrdirrrgkn kvaaqncrkr kmenivgley eldslkedke rlmkeksers sslremkqql
      541 stlyhevfsm lrdehgkpfs pneyslqhta dgtvflvprl kkilvknn
//
LOCUS       XP_026128424             341 aa            linear   VRT 18-JUN-2025
DEFINITION  heterogeneous nuclear ribonucleoprotein A3 [Carassius auratus].
ACCESSION   XP_026128424
VERSION     XP_026128424.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272639.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..341
                     /product="heterogeneous nuclear ribonucleoprotein A3"
                     /calculated_mol_wt=35709
     Region          14..91
                     /region_name="RRM1_hnRNPA_like"
                     /note="RNA recognition motif 1 (RRM1) found in
                     heterogeneous nuclear ribonucleoprotein A subfamily;
                     cd12578"
                     /db_xref="CDD:409992"
     Site            order(14,16,18..19,41,43,45,54..56,58,81,84,86..91)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:409992"
     Region          104..183
                     /region_name="RRM2_hnRNPA3"
                     /note="RNA recognition motif 2 (RRM2) found in
                     heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3) and
                     similar proteins; cd12582"
                     /db_xref="CDD:409996"
     Region          295..>318
                     /region_name="HnRNPA1"
                     /note="Nuclear factor hnRNPA1; pfam11627"
                     /db_xref="CDD:463312"
     CDS             1..341
                     /gene="hnrnpa3"
                     /coded_by="XM_026272639.1:97..1122"
                     /db_xref="GeneID:113109093"
ORIGIN      
        1 meggerkepe qlrklfiggl sfettedslr ahfeqwgklt dcvvmrdpan krsrgfgfvt
       61 yscvaevdaa maarphkvdg rvvepkravs redsnkpgah ltvkkifvgg ikedteeyhi
      121 reyfecygki etidimeers tgkkrgfcfv tfddhdtvdk ivaqkyhtin shncevrkal
      181 pkqdmqavsn qryrgggggn lmgrgggggn fgggdfdrgg yggggrggsg ggdryngfgg
      241 nygggpgygg grggpgygnq gggrfggydn yndggnfggn fggggggggg gnyndfgnya
      301 gqqsnygpmk gnnfggrnsg pygggygsgg gggggygsrr y
//
LOCUS       XP_026128425             341 aa            linear   VRT 18-JUN-2025
DEFINITION  heterogeneous nuclear ribonucleoprotein A3 [Carassius auratus].
ACCESSION   XP_026128425
VERSION     XP_026128425.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272640.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..341
                     /product="heterogeneous nuclear ribonucleoprotein A3"
                     /calculated_mol_wt=35709
     Region          14..91
                     /region_name="RRM1_hnRNPA_like"
                     /note="RNA recognition motif 1 (RRM1) found in
                     heterogeneous nuclear ribonucleoprotein A subfamily;
                     cd12578"
                     /db_xref="CDD:409992"
     Site            order(14,16,18..19,41,43,45,54..56,58,81,84,86..91)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:409992"
     Region          104..183
                     /region_name="RRM2_hnRNPA3"
                     /note="RNA recognition motif 2 (RRM2) found in
                     heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3) and
                     similar proteins; cd12582"
                     /db_xref="CDD:409996"
     Region          295..>318
                     /region_name="HnRNPA1"
                     /note="Nuclear factor hnRNPA1; pfam11627"
                     /db_xref="CDD:463312"
     CDS             1..341
                     /gene="hnrnpa3"
                     /coded_by="XM_026272640.1:97..1122"
                     /db_xref="GeneID:113109093"
ORIGIN      
        1 meggerkepe qlrklfiggl sfettedslr ahfeqwgklt dcvvmrdpan krsrgfgfvt
       61 yscvaevdaa maarphkvdg rvvepkravs redsnkpgah ltvkkifvgg ikedteeyhi
      121 reyfecygki etidimeers tgkkrgfcfv tfddhdtvdk ivaqkyhtin shncevrkal
      181 pkqdmqavsn qryrgggggn lmgrgggggn fgggdfdrgg yggggrggsg ggdryngfgg
      241 nygggpgygg grggpgygnq gggrfggydn yndggnfggn fggggggggg gnyndfgnya
      301 gqqsnygpmk gnnfggrnsg pygggygsgg gggggygsrr y
//
LOCUS       XP_026128426             396 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D3a [Carassius auratus].
ACCESSION   XP_026128426
VERSION     XP_026128426.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272641.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..396
                     /product="homeobox protein Hox-D3a"
                     /calculated_mol_wt=42912
     Region          116..237
                     /region_name="COG5576"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]"
                     /db_xref="CDD:227863"
     Region          162..218
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     Region          333..394
                     /region_name="DUF4074"
                     /note="Domain of unknown function (DUF4074); pfam13293"
                     /db_xref="CDD:463833"
     CDS             1..396
                     /gene="hoxd3a"
                     /coded_by="XM_026272641.1:2021..3211"
                     /db_xref="GeneID:113109095"
ORIGIN      
        1 mqkatyydna glfggysypk sdsytygpth qgfssssmen dfqnpicpiq ttsirppahk
       61 ngdisgscmr psasqgnsqt esiseqqqaa plaasspspn ssstqkkksp sttgsstatp
      121 viakqifpwm kesrqnakqk ntncpaaget cddksppgpa skrvrtayts aqlvelekef
      181 hfnrylcrpr rvemanllnl terqikiwfq nrrmkykkdq kskgimhspl ghspdrsppl
      241 sgsnhigysg qlpnvnglsy dapsppsfak pqqnmyglaa ytaplggcip qqkrypgaey
      301 ehhsmqgngs fananlqssp vyvggnfvds mpasgpmfnl ghlphpssas vdyscaaqip
      361 gnhhhgpcdp hptytdlssh hasqgrlqda pklthl
//
LOCUS       XP_026128427             396 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D3a [Carassius auratus].
ACCESSION   XP_026128427
VERSION     XP_026128427.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272642.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..396
                     /product="homeobox protein Hox-D3a"
                     /calculated_mol_wt=42912
     Region          116..237
                     /region_name="COG5576"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]"
                     /db_xref="CDD:227863"
     Region          162..218
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     Region          333..394
                     /region_name="DUF4074"
                     /note="Domain of unknown function (DUF4074); pfam13293"
                     /db_xref="CDD:463833"
     CDS             1..396
                     /gene="hoxd3a"
                     /coded_by="XM_026272642.1:1445..2635"
                     /db_xref="GeneID:113109095"
ORIGIN      
        1 mqkatyydna glfggysypk sdsytygpth qgfssssmen dfqnpicpiq ttsirppahk
       61 ngdisgscmr psasqgnsqt esiseqqqaa plaasspspn ssstqkkksp sttgsstatp
      121 viakqifpwm kesrqnakqk ntncpaaget cddksppgpa skrvrtayts aqlvelekef
      181 hfnrylcrpr rvemanllnl terqikiwfq nrrmkykkdq kskgimhspl ghspdrsppl
      241 sgsnhigysg qlpnvnglsy dapsppsfak pqqnmyglaa ytaplggcip qqkrypgaey
      301 ehhsmqgngs fananlqssp vyvggnfvds mpasgpmfnl ghlphpssas vdyscaaqip
      361 gnhhhgpcdp hptytdlssh hasqgrlqda pklthl
//
LOCUS       XP_026128428             396 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D3a [Carassius auratus].
ACCESSION   XP_026128428
VERSION     XP_026128428.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272643.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..396
                     /product="homeobox protein Hox-D3a"
                     /calculated_mol_wt=42912
     Region          116..237
                     /region_name="COG5576"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]"
                     /db_xref="CDD:227863"
     Region          162..218
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     Region          333..394
                     /region_name="DUF4074"
                     /note="Domain of unknown function (DUF4074); pfam13293"
                     /db_xref="CDD:463833"
     CDS             1..396
                     /gene="hoxd3a"
                     /coded_by="XM_026272643.1:812..2002"
                     /db_xref="GeneID:113109095"
ORIGIN      
        1 mqkatyydna glfggysypk sdsytygpth qgfssssmen dfqnpicpiq ttsirppahk
       61 ngdisgscmr psasqgnsqt esiseqqqaa plaasspspn ssstqkkksp sttgsstatp
      121 viakqifpwm kesrqnakqk ntncpaaget cddksppgpa skrvrtayts aqlvelekef
      181 hfnrylcrpr rvemanllnl terqikiwfq nrrmkykkdq kskgimhspl ghspdrsppl
      241 sgsnhigysg qlpnvnglsy dapsppsfak pqqnmyglaa ytaplggcip qqkrypgaey
      301 ehhsmqgngs fananlqssp vyvggnfvds mpasgpmfnl ghlphpssas vdyscaaqip
      361 gnhhhgpcdp hptytdlssh hasqgrlqda pklthl
//
LOCUS       XP_026128429             396 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D3a [Carassius auratus].
ACCESSION   XP_026128429
VERSION     XP_026128429.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272644.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..396
                     /product="homeobox protein Hox-D3a"
                     /calculated_mol_wt=42912
     Region          116..237
                     /region_name="COG5576"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]"
                     /db_xref="CDD:227863"
     Region          162..218
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     Region          333..394
                     /region_name="DUF4074"
                     /note="Domain of unknown function (DUF4074); pfam13293"
                     /db_xref="CDD:463833"
     CDS             1..396
                     /gene="hoxd3a"
                     /coded_by="XM_026272644.1:298..1488"
                     /db_xref="GeneID:113109095"
ORIGIN      
        1 mqkatyydna glfggysypk sdsytygpth qgfssssmen dfqnpicpiq ttsirppahk
       61 ngdisgscmr psasqgnsqt esiseqqqaa plaasspspn ssstqkkksp sttgsstatp
      121 viakqifpwm kesrqnakqk ntncpaaget cddksppgpa skrvrtayts aqlvelekef
      181 hfnrylcrpr rvemanllnl terqikiwfq nrrmkykkdq kskgimhspl ghspdrsppl
      241 sgsnhigysg qlpnvnglsy dapsppsfak pqqnmyglaa ytaplggcip qqkrypgaey
      301 ehhsmqgngs fananlqssp vyvggnfvds mpasgpmfnl ghlphpssas vdyscaaqip
      361 gnhhhgpcdp hptytdlssh hasqgrlqda pklthl
//
LOCUS       XP_026128430             396 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D3a [Carassius auratus].
ACCESSION   XP_026128430
VERSION     XP_026128430.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272645.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..396
                     /product="homeobox protein Hox-D3a"
                     /calculated_mol_wt=42912
     Region          116..237
                     /region_name="COG5576"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]"
                     /db_xref="CDD:227863"
     Region          162..218
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     Region          333..394
                     /region_name="DUF4074"
                     /note="Domain of unknown function (DUF4074); pfam13293"
                     /db_xref="CDD:463833"
     CDS             1..396
                     /gene="hoxd3a"
                     /coded_by="XM_026272645.1:2405..3595"
                     /db_xref="GeneID:113109095"
ORIGIN      
        1 mqkatyydna glfggysypk sdsytygpth qgfssssmen dfqnpicpiq ttsirppahk
       61 ngdisgscmr psasqgnsqt esiseqqqaa plaasspspn ssstqkkksp sttgsstatp
      121 viakqifpwm kesrqnakqk ntncpaaget cddksppgpa skrvrtayts aqlvelekef
      181 hfnrylcrpr rvemanllnl terqikiwfq nrrmkykkdq kskgimhspl ghspdrsppl
      241 sgsnhigysg qlpnvnglsy dapsppsfak pqqnmyglaa ytaplggcip qqkrypgaey
      301 ehhsmqgngs fananlqssp vyvggnfvds mpasgpmfnl ghlphpssas vdyscaaqip
      361 gnhhhgpcdp hptytdlssh hasqgrlqda pklthl
//
LOCUS       XP_026128431             331 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D10a [Carassius auratus].
ACCESSION   XP_026128431
VERSION     XP_026128431.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272646.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..331
                     /product="homeobox protein Hox-D10a"
                     /calculated_mol_wt=37397
     Region          203..>320
                     /region_name="COG5576"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]"
                     /db_xref="CDD:227863"
     Region          258..314
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..331
                     /gene="hoxd10a"
                     /coded_by="XM_026272646.1:901..1896"
                     /db_xref="GeneID:113109096"
ORIGIN      
        1 msfpnsspaa ntflvdslig acrtdfysss nmympataem gtygmqtcgl lpslgkrgev
       61 nhqnmgmnvh syipqtdnwa dpsrscrldq plnqmstctf sqsikeetnc cmysdkrakv
      121 ssseipaysn lisetcsvds peipvpgyfr lsqtyatakn ldydsetmsp sttlmqlnrv
      181 tpkaqstpfv evekklpldr dtrssspaqt pepkvstlee kncsteasvs spelphregk
      241 eskndtptsn wltaksgrkk rcpytkhqtl elekeflfnm yltrerrlei sksvnltdrq
      301 vkiwfqnrrm klkkmsrenr ireltsnltf s
//
LOCUS       XP_026128432             258 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D9a [Carassius auratus].
ACCESSION   XP_026128432
VERSION     XP_026128432.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272647.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..258
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..258
                     /product="homeobox protein Hox-D9a"
                     /calculated_mol_wt=29046
     Region          1..178
                     /region_name="Hox9_act"
                     /note="Hox9 activation region; pfam04617"
                     /db_xref="CDD:461369"
     Region          192..248
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..258
                     /gene="hoxd9a"
                     /coded_by="XM_026272647.1:732..1508"
                     /db_xref="GeneID:113109098"
ORIGIN      
        1 msgssalssy yvdsimghdt edvygaryvq gshtvrpsgv aenadfsscs fapksavfpa
       61 swtsvhqpst aavsglyhpy vhqshlsdnr yvrswiepvs shislsglhs ssrhsgtktq
      121 slpskrteca afeaetpvvp efscsavses vdqateetvt ndisshgepk dekqqldpsn
      181 paanwihars trkkrcpytk yqtlelekef lynmyltrdr ryevarilnl terqvkiwfq
      241 nrrmkmkkmn rersskdp
//
LOCUS       XP_026128433             256 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D4a [Carassius auratus].
ACCESSION   XP_026128433
VERSION     XP_026128433.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272648.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..256
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..256
                     /product="homeobox protein Hox-D4a"
                     /calculated_mol_wt=29193
     Region          167..223
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..256
                     /gene="hoxd4a"
                     /coded_by="XM_026272648.1:1101..1871"
                     /db_xref="GeneID:113109099"
ORIGIN      
        1 meggkkdnsr kisisylqkl mamssymvns kyvdptfppc eeysqnsyip eqspgyysps
       61 qdtdfqhpgi ysrsnyseqp yscntvqgss vqprghvqdp aghpspypaq teqcpavqis
      121 gprtcgpqqn tksqngipak qpavvypwmk kvhvttvnpd ytgpepkrsr taytrqqvle
      181 lekefhfnry ltrrrrieia htlclserqi kiwfqnrrmk wkkdhklpnt kgrsasagnq
      241 haqhaqkdsq teittl
//
LOCUS       XP_026128434             276 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D11a [Carassius auratus].
ACCESSION   XP_026128434
VERSION     XP_026128434.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272649.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..276
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..276
                     /product="homeobox protein Hox-D11a"
                     /calculated_mol_wt=31989
     Region          23..138
                     /region_name="DUF3528"
                     /note="Protein of unknown function (DUF3528); pfam12045"
                     /db_xref="CDD:432284"
     Region          205..261
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..276
                     /gene="hoxd11a"
                     /coded_by="XM_026272649.1:181..1011"
                     /db_xref="GeneID:113109100"
ORIGIN      
        1 mtdyedrsnc asnmylpyyv sapdfssvss flpqttacqv nfpyssnlaq vqpvrevtfr
       61 dygldhpskw hyrgnyasyy steeimhrdl lqssnraemi fkndsmyshh ggtnsscnff
      121 tnvgqngvlp qgfdqffesv nsekpnpeqs kqkpdtsvpg daacnvstds aeqtkrnpte
      181 tmeeessist cdeeknsdss atksrkkrcp yskyqirele refffnvyin kekrlqlsrm
      241 lsltdrqvki wfqnrrmkek klnrdrlqyf tgnplf
//
LOCUS       XP_026128435             266 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-D12a [Carassius auratus].
ACCESSION   XP_026128435
VERSION     XP_026128435.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272650.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..266
                     /product="homeobox protein Hox-D12a"
                     /calculated_mol_wt=30339
     Region          199..255
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..266
                     /gene="hoxd12a"
                     /coded_by="XM_026272650.1:219..1019"
                     /db_xref="GeneID:113109101"
ORIGIN      
        1 mcehnllssg yvapllnfhs sdslylqnlr gngvhlsgls qmsygrrelc slpwtspssc
       61 ttptqsrays gysqpffsss aavsaslnth kkgsleesgr yyfqdvshks eepgrpnasy
      121 aseqrltsds asnevsnler rqqnrlaqne lnfidqpvtd askqsvssia qmqpsldtpt
      181 irsafsdglp wcpsqvrsrk krkpytktql aelenefmmn efinrqkrke lserlelsdq
      241 qvkiwfqnrr mkkkrlmmre htfivy
//
LOCUS       XP_026128436             251 aa            linear   VRT 18-JUN-2025
DEFINITION  LOW QUALITY PROTEIN: homeobox protein Hox-D13a [Carassius auratus].
ACCESSION   XP_026128436
VERSION     XP_026128436.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272651.1
KEYWORDS    RefSeq; corrected model.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            frameshifts :: corrected 1 indel
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..251
                     /product="LOW QUALITY PROTEIN: homeobox protein Hox-D13a"
                     /calculated_mol_wt=28290
     Region          189..245
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..251
                     /gene="hoxd13a"
                     /coded_by="XM_026272651.1:117..872"
                     /note="The sequence of the model RefSeq protein was
                     modified relative to its source genomic sequence to
                     represent the inferred CDS: deleted 1 base in 1 codon"
                     /db_xref="GeneID:113109102"
ORIGIN      
        1 mearglneel rnvypsafra hssrsaaetp vfstaerpts tsaesltpyv sfpanigtss
       61 svtfgcrlvs cygckvsqna vfpssvvkqn angqsaskpv dygwlkevaf yqsytgsypv
      121 yfdlpvvhkt magdsrhetc ltmedhppwk wsnncssqly cskdqtqsqh fwkpsltegt
      181 ggsfcprgrk krvpytklql kelereyttt tfitkekrrl iafytnlser qviigfqnrr
      241 indkkrpnic i
//
LOCUS       XP_026128437             416 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox even-skipped homolog protein 2 [Carassius auratus].
ACCESSION   XP_026128437
VERSION     XP_026128437.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272652.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..416
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..416
                     /product="homeobox even-skipped homolog protein 2"
                     /calculated_mol_wt=44413
     Region          170..226
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..416
                     /gene="evx2"
                     /coded_by="XM_026272652.1:880..2130"
                     /db_xref="GeneID:113109103"
ORIGIN      
        1 mmerirkemi lmerglhspv agkrlsdsag navlealens qhagrlspri tsaslhgnlg
       61 diptkgkfei dslfgnhhsd ntsstevsss enrkkinlyp evspdsdmns dvevgcpshr
      121 spsslsqqke nnskgfsdsn sgasntssss lsnmngsisn sssssadqvr ryrtaftreq
      181 igrlekefyr enyvsrprrc elaaalnlpe ttikvwfqnr rmkdkrqrla mswphpadps
      241 fytymmthaa atgslpypfh shmplhyyph vgvtaaaaaa aasgaasspf atsirpldtf
      301 ralshpysrp ellcsfrhpg lyqspaglns saaaaaaaaa aaaavsapsa tgpcsclsch
      361 ssqaasalgs rstssdftct asgqrsesgf lpysaavlsk tavpspdqre esalnr
//
LOCUS       XP_026128438             392 aa            linear   VRT 18-JUN-2025
DEFINITION  endoplasmic reticulum junction formation protein lunapark-A-like
            [Carassius auratus].
ACCESSION   XP_026128438
VERSION     XP_026128438.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272653.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..392
                     /product="endoplasmic reticulum junction formation protein
                     lunapark-A-like"
                     /calculated_mol_wt=43444
     Region          246..296
                     /region_name="zinc_ribbon_10"
                     /note="Predicted integral membrane zinc-ribbon
                     metal-binding protein; pfam10058"
                     /db_xref="CDD:401882"
     CDS             1..392
                     /gene="LOC113109104"
                     /coded_by="XM_026272653.1:187..1365"
                     /db_xref="GeneID:113109104"
ORIGIN      
        1 mgavvsrwra kpttvevleg ldkdiqslee nreknqkqlk lwvyrlllys allyliactv
       61 vyvwyiperm igkvivaspf llfpllvwll rkllivlynk rternnekle elraekkkil
      121 eqvmetetyk naklilerfd pdskkkleie aqpigppatp rqgqelrqrl vtprptgrpp
      181 pvpgpsappt plsapggppe kglststphg lirrpgtpag tpgavmgmhp pgpplarpil
      241 prergamdrv veylvgdgpq nryalicqqc sshngmalke efeyiafrca ycyflnpark
      301 trpqaprlpe ftadtktspe sdppavamet dlsssppape gkaaspglvk aeageqqapd
      361 slleekhped pdltsvpdkp edehnvsame vd
//
LOCUS       XP_026128439             499 aa            linear   VRT 18-JUN-2025
DEFINITION  cyclic AMP-dependent transcription factor ATF-2 isoform X1
            [Carassius auratus].
ACCESSION   XP_026128439
VERSION     XP_026128439.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272654.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..499
                     /product="cyclic AMP-dependent transcription factor ATF-2
                     isoform X1"
                     /calculated_mol_wt=53865
     Region          39..61
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275370"
     Region          77..114
                     /region_name="GCN4_cent"
                     /note="GCN4 central activation domain-like acidic
                     activation domain; cd12192"
                     /db_xref="CDD:213399"
     Site            order(88..89,91..92,100..101,103..105,107..108,112..114)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:213399"
     Region          363..423
                     /region_name="bZIP_ATF2"
                     /note="Basic leucine zipper (bZIP) domain of Activating
                     Transcription Factor-2 (ATF-2) and similar proteins: a
                     DNA-binding and dimerization domain; cd14687"
                     /db_xref="CDD:269835"
     Region          363..423
                     /region_name="coiled coil"
                     /note="coiled coil [structural motif]"
                     /db_xref="CDD:269835"
     Site            order(364,368,370..372,375,377..379,381..383)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:269835"
     Site            order(382,389..390,392..393,396..397,400,403..404,407,
                     410..411,413..414,417..418,421..422)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:269835"
     CDS             1..499
                     /gene="LOC113109105"
                     /coded_by="XM_026272654.1:110..1609"
                     /db_xref="GeneID:113109105"
ORIGIN      
        1 mrdedvnnlf sddtvllsle ilgwqteavn msddkpflct apgcgqrftn edhlavhkhk
       61 hemtlrfgpa rndsviiadq tptptrflkn ceevglfnel tspfehdfkk ateddikklp
      121 ldlsplatpv vrnkieehtp ieshrdsplp hpestttddk evclqptslp pstivrpasl
      181 qvpsvllasn viqqalpspt sssvitqlps ssrpivpvsg tfpvllqlsn gqtmpvaipa
      241 tisssvhipt aiplvrpvtv vpsvpgipgp sspqpvqsea kmklkaalsq qlpqvssgdt
      301 gdiqsssasq tpppapppae eprpqslqqp atsttetpvs psqhtsstgg rrrrttsedp
      361 dekrrkfler nraaasrcrq krkvwvqnle kkaedlssvn gqlqnevtll rsevsqlkql
      421 llahrdcpvt llqkksgnhq lekedsggem svpsspqnea iqhssistsn glrslasgpa
      481 adhsteeedd sshaqssgs
//
LOCUS       XP_026128440             472 aa            linear   VRT 18-JUN-2025
DEFINITION  cyclic AMP-dependent transcription factor ATF-2 isoform X2
            [Carassius auratus].
ACCESSION   XP_026128440
VERSION     XP_026128440.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272655.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..472
                     /product="cyclic AMP-dependent transcription factor ATF-2
                     isoform X2"
                     /calculated_mol_wt=51274
     Region          39..61
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275370"
     Region          77..114
                     /region_name="GCN4_cent"
                     /note="GCN4 central activation domain-like acidic
                     activation domain; cd12192"
                     /db_xref="CDD:213399"
     Site            order(88..89,91..92,100..101,103..105,107..108,112..114)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:213399"
     Region          363..>405
                     /region_name="bZIP_ATF2"
                     /note="Basic leucine zipper (bZIP) domain of Activating
                     Transcription Factor-2 (ATF-2) and similar proteins: a
                     DNA-binding and dimerization domain; cd14687"
                     /db_xref="CDD:269835"
     Site            order(364,368,370..372,375,377..379,381..383)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:269835"
     CDS             1..472
                     /gene="LOC113109105"
                     /coded_by="XM_026272655.1:431..1849"
                     /db_xref="GeneID:113109105"
ORIGIN      
        1 mrdedvnnlf sddtvllsle ilgwqteavn msddkpflct apgcgqrftn edhlavhkhk
       61 hemtlrfgpa rndsviiadq tptptrflkn ceevglfnel tspfehdfkk ateddikklp
      121 ldlsplatpv vrnkieehtp ieshrdsplp hpestttddk evclqptslp pstivrpasl
      181 qvpsvllasn viqqalpspt sssvitqlps ssrpivpvsg tfpvllqlsn gqtmpvaipa
      241 tisssvhipt aiplvrpvtv vpsvpgipgp sspqpvqsea kmklkaalsq qlpqvssgdt
      301 gdiqsssasq tpppapppae eprpqslqqp atsttetpvs psqhtsstgg rrrrttsedp
      361 dekrrkfler nraaasrcrq krkvwvqnle kkaedlssvn gqlqswrrrt aagrclfpaa
      421 hrtrpsstap sahptasars prappqttaq rrkttprths lqeadpasdw sr
//
LOCUS       XP_026128441             469 aa            linear   VRT 18-JUN-2025
DEFINITION  cyclic AMP-dependent transcription factor ATF-2 isoform X3
            [Carassius auratus].
ACCESSION   XP_026128441
VERSION     XP_026128441.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272656.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..469
                     /product="cyclic AMP-dependent transcription factor ATF-2
                     isoform X3"
                     /calculated_mol_wt=50446
     Region          9..31
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275370"
     Region          47..84
                     /region_name="GCN4_cent"
                     /note="GCN4 central activation domain-like acidic
                     activation domain; cd12192"
                     /db_xref="CDD:213399"
     Site            order(58..59,61..62,70..71,73..75,77..78,82..84)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:213399"
     Region          333..393
                     /region_name="bZIP_ATF2"
                     /note="Basic leucine zipper (bZIP) domain of Activating
                     Transcription Factor-2 (ATF-2) and similar proteins: a
                     DNA-binding and dimerization domain; cd14687"
                     /db_xref="CDD:269835"
     Region          333..393
                     /region_name="coiled coil"
                     /note="coiled coil [structural motif]"
                     /db_xref="CDD:269835"
     Site            order(334,338,340..342,345,347..349,351..353)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:269835"
     Site            order(352,359..360,362..363,366..367,370,373..374,377,
                     380..381,383..384,387..388,391..392)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:269835"
     CDS             1..469
                     /gene="LOC113109105"
                     /coded_by="XM_026272656.1:92..1501"
                     /db_xref="GeneID:113109105"
ORIGIN      
        1 msddkpflct apgcgqrftn edhlavhkhk hemtlrfgpa rndsviiadq tptptrflkn
       61 ceevglfnel tspfehdfkk ateddikklp ldlsplatpv vrnkieehtp ieshrdsplp
      121 hpestttddk evclqptslp pstivrpasl qvpsvllasn viqqalpspt sssvitqlps
      181 ssrpivpvsg tfpvllqlsn gqtmpvaipa tisssvhipt aiplvrpvtv vpsvpgipgp
      241 sspqpvqsea kmklkaalsq qlpqvssgdt gdiqsssasq tpppapppae eprpqslqqp
      301 atsttetpvs psqhtsstgg rrrrttsedp dekrrkfler nraaasrcrq krkvwvqnle
      361 kkaedlssvn gqlqnevtll rsevsqlkql llahrdcpvt llqkksgnhq lekedsggem
      421 svpsspqnea iqhssistsn glrslasgpa adhsteeedd sshaqssgs
//
LOCUS       XP_026128442             154 aa            linear   VRT 18-JUN-2025
DEFINITION  ATP synthase F(0) complex subunit C1, mitochondrial isoform X1
            [Carassius auratus].
ACCESSION   XP_026128442
VERSION     XP_026128442.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272657.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..154
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..154
                     /product="ATP synthase F(0) complex subunit C1,
                     mitochondrial isoform X1"
                     /calculated_mol_wt=15854
     Region          80..154
                     /region_name="ATP9"
                     /note="ATP synthase F0 subunit 9; Provisional; MTH00222"
                     /db_xref="CDD:164765"
     CDS             1..154
                     /gene="atp5mc3a"
                     /coded_by="XM_026272657.1:55..519"
                     /db_xref="GeneID:113109106"
ORIGIN      
        1 mrssagvfdl clskseaahn hspvnmftca kistaalvrv gsrslfrpvs aavlsrpevk
       61 pevppqsalr slqtsavsrd idtaakfiga gaatvgvags gagigtvfgs liigyarnps
      121 lkqqlfsyai lgfalseamg lfclmvafli lfam
//
LOCUS       XP_026128443             129 aa            linear   VRT 18-JUN-2025
DEFINITION  ATP synthase F(0) complex subunit C3, mitochondrial isoform X2
            [Carassius auratus].
ACCESSION   XP_026128443
VERSION     XP_026128443.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272658.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..129
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..129
                     /product="ATP synthase F(0) complex subunit C3,
                     mitochondrial isoform X2"
                     /calculated_mol_wt=13214
     Region          55..129
                     /region_name="ATP9"
                     /note="ATP synthase F0 subunit 9; Provisional; MTH00222"
                     /db_xref="CDD:164765"
     CDS             1..129
                     /gene="atp5mc3a"
                     /coded_by="XM_026272658.1:118..507"
                     /db_xref="GeneID:113109106"
ORIGIN      
        1 mftcakista alvrvgsrsl frpvsaavls rpevkpevpp qsalrslqts avsrdidtaa
       61 kfigagaatv gvagsgagig tvfgsliigy arnpslkqql fsyailgfal seamglfclm
      121 vaflilfam
//
LOCUS       XP_026128444             459 aa            linear   VRT 18-JUN-2025
DEFINITION  N-chimaerin [Carassius auratus].
ACCESSION   XP_026128444
VERSION     XP_026128444.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272659.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..459
                     /product="N-chimaerin"
                     /calculated_mol_wt=52752
     Region          42..128
                     /region_name="SH2_a2chimerin_b2chimerin"
                     /note="Src homology 2 (SH2) domain found in
                     alpha2-chimerin and beta2-chimerin proteins; cd10352"
                     /db_xref="CDD:198215"
     Site            order(56,73,94,96)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198215"
     Site            order(95,116)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198215"
     Region          201..257
                     /region_name="C1_alphaCHN"
                     /note="protein kinase C conserved region 1 (C1 domain)
                     found in alpha-chimaerin and similar proteins; cd20856"
                     /db_xref="CDD:410406"
     Site            order(211..217,225..229,232)
                     /site_type="other"
                     /note="putative DAG/PE binding site [chemical binding]"
                     /db_xref="CDD:410406"
     Region          266..459
                     /region_name="RhoGAP_chimaerin"
                     /note="RhoGAP (GTPase-activator protein [GAP] for Rho-like
                     small GTPases) domain of chimaerins. Chimaerins are a
                     family of phorbolester- and diacylglycerol-responsive GAPs
                     specific for the Rho-like GTPase Rac. Chimaerins exist in
                     two alternative splice forms...; cd04372"
                     /db_xref="CDD:239837"
     Site            order(304,344,348,417,420..421,445)
                     /site_type="other"
                     /note="putative GTPase interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:239837"
     Site            304
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:239837"
     CDS             1..459
                     /gene="LOC113109107"
                     /coded_by="XM_026272659.1:278..1657"
                     /db_xref="GeneID:113109107"
ORIGIN      
        1 mallvfdnde yrppvwksyl yqlqqeaphp rrvtcvseve nrpkhygrey hgmisreead
       61 qllsvsegsy liresqrqpg tytlalrfgn qtrnfrlfyd gkhfvgekrf esihdlvtdg
      121 litlyietka aeyiskmtin piyehvgytt lnrepalkka lpvcrdlpdg kdaagedtgl
      181 eerltslvrr atlkesewap kydkvhnfkv htfrgphwce ycanfmwgli aqgvkcadcg
      241 lnvhkqcskm vpndckpdlk hvkkvyscdl ttlvkahntt rpmvvdmcir eiearglkse
      301 glyrvsgfsd liedvklsfd rdgekadisv nvyedinvit galklyfrdl pipvityday
      361 prfietaklt dpderlealh ealkqmppah cetlrylmah lkrvtqnekh nlmnaenlgi
      421 vfgptlmrap dldamtalnd iryqrqvvel liknedilf
//
LOCUS       XP_026128445             437 aa            linear   VRT 18-JUN-2025
DEFINITION  WAS/WASL-interacting protein family member 1-like isoform X1
            [Carassius auratus].
ACCESSION   XP_026128445
VERSION     XP_026128445.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272660.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..437
                     /product="WAS/WASL-interacting protein family member
                     1-like isoform X1"
                     /calculated_mol_wt=43498
     Region          30..61
                     /region_name="WH2_WAS_WASL-1"
                     /note="Wiskott Aldrich syndrome homology region 2 (WH2
                     motif) in WAS/WASL-interacting protein family member 1;
                     cd22076"
                     /db_xref="CDD:409219"
     Site            order(30..34,36..38,40..42,45,47..61)
                     /site_type="other"
                     /note="actin-binding motif [polypeptide binding]"
                     /db_xref="CDD:409219"
     Region          47..50
                     /region_name="actin-binding sequence"
                     /note="actin-binding sequence [structural motif]"
                     /db_xref="CDD:409219"
     CDS             1..437
                     /gene="LOC113109108"
                     /coded_by="XM_026272660.1:263..1576"
                     /db_xref="GeneID:113109108"
ORIGIN      
        1 msgppppppp gppptfsqan iekpalnkse kqgrnallsd iskgarlkka vtndrsapvl
       61 dkpkgggggg gggggggggg gggapgglgg lfqggmprlr ssggntaarp pmpptagrfp
      121 apsspagnrp plptagrpsp gragplppsv rspsspsgpp plpggrpsss spsvpapsqp
      181 grrpslpppr dpqpsfpppp mptsarpppa tipsrpsddf pppppptggs rasfsrdgpl
      241 pppppstesk plssqrpmgn pppslppgrg gvppippspr depstrgspr nslppppppg
      301 rssplppppn erppppgrgp strsgplppp pagggggrgv spplpppnrp ggsgrpplpp
      361 dpprvpsfpp pppdtingyq sppapatdew gmrfsfhpps efpppepfvs fpktypsksg
      421 gkgtrdrgap plpplpr
//
LOCUS       XP_026128446             436 aa            linear   VRT 18-JUN-2025
DEFINITION  WAS/WASL-interacting protein family member 1-like isoform X2
            [Carassius auratus].
ACCESSION   XP_026128446
VERSION     XP_026128446.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272661.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..436
                     /product="WAS/WASL-interacting protein family member
                     1-like isoform X2"
                     /calculated_mol_wt=43427
     Region          30..61
                     /region_name="WH2_WAS_WASL-1"
                     /note="Wiskott Aldrich syndrome homology region 2 (WH2
                     motif) in WAS/WASL-interacting protein family member 1;
                     cd22076"
                     /db_xref="CDD:409219"
     Site            order(30..34,36..38,40..42,45,47..61)
                     /site_type="other"
                     /note="actin-binding motif [polypeptide binding]"
                     /db_xref="CDD:409219"
     Region          47..50
                     /region_name="actin-binding sequence"
                     /note="actin-binding sequence [structural motif]"
                     /db_xref="CDD:409219"
     Region          <101..282
                     /region_name="PRK07764"
                     /note="DNA polymerase III subunits gamma and tau;
                     Validated"
                     /db_xref="CDD:236090"
     CDS             1..436
                     /gene="LOC113109108"
                     /coded_by="XM_026272661.1:268..1578"
                     /db_xref="GeneID:113109108"
ORIGIN      
        1 msgppppppp gppptfsqan iekpalnkse kqgrnallsd iskgarlkka vtndrsapvl
       61 dkpkgggggg gggggggggg gggapgglgg lfqggmprlr ssggntarpp mpptagrfpa
      121 psspagnrpp lptagrpspg ragplppsvr spsspsgppp lpggrpssss psvpapsqpg
      181 rrpslppprd pqpsfppppm ptsarpppat ipsrpsddfp ppppptggsr asfsrdgplp
      241 ppppsteskp lssqrpmgnp ppslppgrgg vppippsprd epstrgsprn slppppppgr
      301 ssplppppne rppppgrgps trsgplpppp agggggrgvs pplpppnrpg gsgrpplppd
      361 pprvpsfppp ppdtingyqs ppapatdewg mrfsfhppse fpppepfvsf pktypsksgg
      421 kgtrdrgapp lpplpr
//
LOCUS       XP_026128447             802 aa            linear   VRT 18-JUN-2025
DEFINITION  integral membrane protein GPR155-like isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128447
VERSION     XP_026128447.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272662.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..802
                     /product="integral membrane protein GPR155-like isoform
                     X1"
                     /calculated_mol_wt=88807
     Region          31..357
                     /region_name="YfdV"
                     /note="Predicted permease, AEC (auxin efflux carrier)
                     family [General function prediction only]; COG0679"
                     /db_xref="CDD:440443"
     Region          366..>492
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          369..393
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410627"
     Region          402..423
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410627"
     Region          435..457
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410627"
     Region          475..490
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410627"
     Region          719..801
                     /region_name="DEP"
                     /note="DEP domain, named after Dishevelled, Egl-10, and
                     Pleckstrin, where this domain was first discovered. The
                     function of this domain is still not clear, but it is
                     believed to be important for the membrane association of
                     the signaling proteins in which it is...; cl02442"
                     /db_xref="CDD:470580"
     CDS             1..802
                     /gene="LOC113109109"
                     /coded_by="XM_026272662.1:213..2621"
                     /db_xref="GeneID:113109109"
ORIGIN      
        1 mghlslnisi fssrngsdpp svppcmsidk llpallecfg iilcgyiagr tniipatqak
       61 glgsfvskfa lpallfknmv lldfgdviwp fffsilvakv svfffvcvlt llvadresrf
      121 skaglfsifa tqsndfalgf pivealyrnt hpeylqyiyl vapvslmvln plgfalcevq
      181 rrrtgepqpq rklevlgsvl lqvvknpivf mvviglvshf llgqkipafm qefvdglans
      241 fggaalfylg ltmvgqlkkl trstvvalil litakllvmp licrgmvevl drgsrsllnh
      301 tslsnyafly gvfptapsva iyashynmel evvtsgmvig tflsapimfv sawlltipwm
      361 dsdplasalq hvsfnisiis lfalvwsvav mllsrkfhri phiftinlfv aqllacvgmi
      421 awkfmaeqdn flgqvltftl lygslystyi wpglialsll fvrrreevnf rpgltvitgw
      481 gvpvlavsvl lltgerlpnt idsaffygkt qvtctsvvlf gsivlcgvsl tllsrrtqdy
      541 hslergslsd seedthtdig sintdcqmce cvcgplqsvp dttstreetp iqtgqcsqqc
      601 astscllvee eqreadrqnt diqstrhvlv cllltvslla nlssclwwlf nkdpgrlyle
      661 lqffcvvanf gqglisfaff gldkhliisp frkrlaslwq gwgqevtgsa aseeirltct
      721 qfltyhkeqc vrdivhkkrc gessstetfl gsdlvrwlqs vglsrapdea laygcrlleg
      781 gviqhislqh gfqdqalhyr ft
//
LOCUS       XP_026128448             773 aa            linear   VRT 18-JUN-2025
DEFINITION  integral membrane protein GPR155-like isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128448
VERSION     XP_026128448.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272663.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..773
                     /product="integral membrane protein GPR155-like isoform
                     X2"
                     /calculated_mol_wt=85653
     Region          31..357
                     /region_name="YfdV"
                     /note="Predicted permease, AEC (auxin efflux carrier)
                     family [General function prediction only]; COG0679"
                     /db_xref="CDD:440443"
     Region          366..>492
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          369..393
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410627"
     Region          402..423
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410627"
     Region          435..457
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410627"
     Region          475..490
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410627"
     Region          690..772
                     /region_name="DEP"
                     /note="DEP domain, named after Dishevelled, Egl-10, and
                     Pleckstrin, where this domain was first discovered. The
                     function of this domain is still not clear, but it is
                     believed to be important for the membrane association of
                     the signaling proteins in which it is...; cl02442"
                     /db_xref="CDD:470580"
     CDS             1..773
                     /gene="LOC113109109"
                     /coded_by="XM_026272663.1:213..2534"
                     /db_xref="GeneID:113109109"
ORIGIN      
        1 mghlslnisi fssrngsdpp svppcmsidk llpallecfg iilcgyiagr tniipatqak
       61 glgsfvskfa lpallfknmv lldfgdviwp fffsilvakv svfffvcvlt llvadresrf
      121 skaglfsifa tqsndfalgf pivealyrnt hpeylqyiyl vapvslmvln plgfalcevq
      181 rrrtgepqpq rklevlgsvl lqvvknpivf mvviglvshf llgqkipafm qefvdglans
      241 fggaalfylg ltmvgqlkkl trstvvalil litakllvmp licrgmvevl drgsrsllnh
      301 tslsnyafly gvfptapsva iyashynmel evvtsgmvig tflsapimfv sawlltipwm
      361 dsdplasalq hvsfnisiis lfalvwsvav mllsrkfhri phiftinlfv aqllacvgmi
      421 awkfmaeqdn flgqvltftl lygslystyi wpglialsll fvrrreevnf rpgltvitgw
      481 gvpvlavsvl lltgerlpnt idsaffygkt qvtctsvvlf gsivlcgvsl tllsrrtqdy
      541 hslergslsd seedthtdig sintgqcsqq castscllve eeqreadrqn tdiqstrhvl
      601 vcllltvsll anlssclwwl fnkdpgrlyl elqffcvvan fgqglisfaf fgldkhliis
      661 pfrkrlaslw qgwgqevtgs aaseeirltc tqfltyhkeq cvrdivhkkr cgessstetf
      721 lgsdlvrwlq svglsrapde alaygcrlle ggviqhislq hgfqdqalhy rft
//
LOCUS       XP_026128449             706 aa            linear   VRT 18-JUN-2025
DEFINITION  integral membrane protein GPR155-like isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128449
VERSION     XP_026128449.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272664.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..706
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..706
                     /product="integral membrane protein GPR155-like isoform
                     X3"
                     /calculated_mol_wt=77674
     Region          31..357
                     /region_name="YfdV"
                     /note="Predicted permease, AEC (auxin efflux carrier)
                     family [General function prediction only]; COG0679"
                     /db_xref="CDD:440443"
     Region          366..>492
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          369..393
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410627"
     Region          402..423
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410627"
     Region          435..457
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410627"
     Region          475..490
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410627"
     CDS             1..706
                     /gene="LOC113109109"
                     /coded_by="XM_026272664.1:213..2333"
                     /db_xref="GeneID:113109109"
ORIGIN      
        1 mghlslnisi fssrngsdpp svppcmsidk llpallecfg iilcgyiagr tniipatqak
       61 glgsfvskfa lpallfknmv lldfgdviwp fffsilvakv svfffvcvlt llvadresrf
      121 skaglfsifa tqsndfalgf pivealyrnt hpeylqyiyl vapvslmvln plgfalcevq
      181 rrrtgepqpq rklevlgsvl lqvvknpivf mvviglvshf llgqkipafm qefvdglans
      241 fggaalfylg ltmvgqlkkl trstvvalil litakllvmp licrgmvevl drgsrsllnh
      301 tslsnyafly gvfptapsva iyashynmel evvtsgmvig tflsapimfv sawlltipwm
      361 dsdplasalq hvsfnisiis lfalvwsvav mllsrkfhri phiftinlfv aqllacvgmi
      421 awkfmaeqdn flgqvltftl lygslystyi wpglialsll fvrrreevnf rpgltvitgw
      481 gvpvlavsvl lltgerlpnt idsaffygkt qvtctsvvlf gsivlcgvsl tllsrrtqdy
      541 hslergslsd seedthtdig sintdcqmce cvcgplqsvp dttstreetp iqtgqcsqqc
      601 astscllvee eqreadrqnt diqstrhvlv cllltvslla nlssclwwlf nkdpgrlyle
      661 lqffcvvanf gqkevsepva glgsgghrlc svrgdqtdly svphis
//
LOCUS       XP_026128450             704 aa            linear   VRT 18-JUN-2025
DEFINITION  integral membrane protein GPR155-like isoform X4 [Carassius
            auratus].
ACCESSION   XP_026128450
VERSION     XP_026128450.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272665.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..704
                     /product="integral membrane protein GPR155-like isoform
                     X4"
                     /calculated_mol_wt=77417
     Region          31..357
                     /region_name="YfdV"
                     /note="Predicted permease, AEC (auxin efflux carrier)
                     family [General function prediction only]; COG0679"
                     /db_xref="CDD:440443"
     Region          366..>492
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          369..393
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410627"
     Region          402..423
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410627"
     Region          435..457
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410627"
     Region          475..490
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410627"
     CDS             1..704
                     /gene="LOC113109109"
                     /coded_by="XM_026272665.1:213..2327"
                     /db_xref="GeneID:113109109"
ORIGIN      
        1 mghlslnisi fssrngsdpp svppcmsidk llpallecfg iilcgyiagr tniipatqak
       61 glgsfvskfa lpallfknmv lldfgdviwp fffsilvakv svfffvcvlt llvadresrf
      121 skaglfsifa tqsndfalgf pivealyrnt hpeylqyiyl vapvslmvln plgfalcevq
      181 rrrtgepqpq rklevlgsvl lqvvknpivf mvviglvshf llgqkipafm qefvdglans
      241 fggaalfylg ltmvgqlkkl trstvvalil litakllvmp licrgmvevl drgsrsllnh
      301 tslsnyafly gvfptapsva iyashynmel evvtsgmvig tflsapimfv sawlltipwm
      361 dsdplasalq hvsfnisiis lfalvwsvav mllsrkfhri phiftinlfv aqllacvgmi
      421 awkfmaeqdn flgqvltftl lygslystyi wpglialsll fvrrreevnf rpgltvitgw
      481 gvpvlavsvl lltgerlpnt idsaffygkt qvtctsvvlf gsivlcgvsl tllsrrtqdy
      541 hslergslsd seedthtdig sintdcqmce cvcgplqsvp dttstreetp iqtgqcsqqc
      601 astscllvee eqreadrqnt diqstrhvlv cllltvslla nlssclwwlf nkdpgrlyle
      661 lqffcvvanf gqvsepvagl gsgghrlcsv rgdqtdlysv phis
//
LOCUS       XP_026128451             418 aa            linear   VRT 18-JUN-2025
DEFINITION  secernin-3 [Carassius auratus].
ACCESSION   XP_026128451
VERSION     XP_026128451.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272666.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..418
                     /product="secernin-3"
                     /calculated_mol_wt=47189
     Region          35..>264
                     /region_name="PepD"
                     /note="Dipeptidase [Amino acid transport and metabolism];
                     cl41909"
                     /db_xref="CDD:477862"
     CDS             1..418
                     /gene="scrn3"
                     /coded_by="XM_026272666.1:177..1433"
                     /db_xref="GeneID:113109110"
ORIGIN      
        1 myptscdtfv alppstegqr ivfgknsdrp cdevqevvyf pakdhepgek lectyieieq
       61 vaqthavvls rpawlwgaem ganehqvcig neavwgkesv dgqeallgmd lvrlalerad
      121 taeravdvit dllekhgqgg ncmedecglt yhnsflisdr seawvletag kywaaervea
      181 gyrnisneys ittkidrehp elrtyaekqr wwngktefsf akvysysnta rieaaegryc
      241 egrkllqksq ghitaetmme ilrdkesgin meglfmttgs mvsvvpkdqn lpgvhfftat
      301 pdpersvfkp fvfvvdikql khtcspcfge edpvkkkprf qskpnrkhpl flkhegaaii
      361 idsggerger meeemralek qklaemekyl tkgiedatll vhlftdtvde elsiysna
//
LOCUS       XP_026128452             439 aa            linear   VRT 18-JUN-2025
DEFINITION  transcription factor Sp9-like [Carassius auratus].
ACCESSION   XP_026128452
VERSION     XP_026128452.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272667.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..439
                     /product="transcription factor Sp9-like"
                     /calculated_mol_wt=46613
     Region          19..309
                     /region_name="SP9_N"
                     /note="N-terminal domain of transcription factor
                     Specificity Protein (SP) 9 and similar proteins; cd22549"
                     /db_xref="CDD:411695"
     Region          313..332
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(317,319,321,323..324,327..328,331,347,349,353..354,
                     357..358,361,375,377,379,381..382,385..386,389)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          324..351
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          340..362
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          354..377
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          368..390
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          370..390
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..439
                     /gene="LOC113109111"
                     /coded_by="XM_026272667.1:99..1418"
                     /db_xref="GeneID:113109111"
ORIGIN      
        1 matsilgeep rfgttplaml aatcnkignt splttlpdss tfskggfhpw krsssscnlg
       61 sslpgftvat srstsglsss tgsgnsafcl astsptssaf saeysslfsn tasvssqesg
      121 qsafiskvhs saetlyprvg mahpyeswyk sgfhstisge vangastwwd vhtnpgswle
      181 vqnpagslqs slhsgtpqai hsqlsgynpd fsslthsafs stgisptash llstgqhllt
      241 qegfktvipt ytdasatnam isgassgigt ssrssrrysg ratcdcpncq eaerlgpaga
      301 slrrkglhsc hipgcgkvyg ktshlkahlr whtgerpfvc nwlfcgkrft rsdelqrhlr
      361 thtgekrfac pvcnkrfmrs dhlskhikth taggggkkgs dsdtdtsnle tprsespeli
      421 legvnprvtv kdqsphhes
//
LOCUS       XP_026128453             436 aa            linear   VRT 18-JUN-2025
DEFINITION  corepressor interacting with RBPJ 1 [Carassius auratus].
ACCESSION   XP_026128453
VERSION     XP_026128453.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272668.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..436
                     /product="corepressor interacting with RBPJ 1"
                     /calculated_mol_wt=50840
     Region          13..49
                     /region_name="Cir_N"
                     /note="N-terminal domain of CBF1 interacting co-repressor
                     CIR; smart01083"
                     /db_xref="CDD:198151"
     CDS             1..436
                     /gene="cirsr"
                     /coded_by="XM_026272668.1:212..1522"
                     /db_xref="GeneID:113109112"
ORIGIN      
        1 mgksfanfmc kkdfhpasks nikkvwiaeq kltfdkkkqe elmqayvkeq dtynnrllmg
       61 ddrvknglnf myeappgask eetkedgese ykfewqkgap rekyakddmn irdqpfgiqv
      121 rnvrcikchk wghvntdrec plfglsgina ssmasdeagp smhpselmae mrnsgfalkk
      181 cvlgrdstms dpaqdlvase eeddpevqfl kslttkqkqk llrkldrlek kkekkkkskk
      241 ekkkskkkpk kkqaksesss ssssdsssds edekhsgkka kkkskrrrds sgdssserdr
      301 ekdskhthsq hsehrvqrsp dnkhsgergr erhgsrerrt eqsrspqrpr eerergrerh
      361 gsreerergk eryrsasrer erergdrdkg ererernsdr nvrrrsvsre rgrggekhsr
      421 sdsrdaerrt ehsrrk
//
LOCUS       XP_026128454             689 aa            linear   VRT 18-JUN-2025
DEFINITION  transcription factor Sp3 isoform X1 [Carassius auratus].
ACCESSION   XP_026128454
VERSION     XP_026128454.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272669.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..689
                     /product="transcription factor Sp3 isoform X1"
                     /calculated_mol_wt=71646
     Region          22..529
                     /region_name="SP1-4_N"
                     /note="N-terminal domain of transcription factor
                     Specificity Proteins (SP) 1-4; cl41773"
                     /db_xref="CDD:425404"
     Region          528..552
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          530..552
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(537,539,541,543..544,547..548,551,567,569,573..574,
                     577..578,581,595,597,599,601..602,605..606,609)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          558..582
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          560..582
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          574..597
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          588..610
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          590..610
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..689
                     /gene="sp3a"
                     /coded_by="XM_026272669.1:174..2243"
                     /db_xref="GeneID:113109114"
ORIGIN      
        1 mtapegpvka gvmadsssaq dggaeqdgqp sslallaatc tglgspapgp enrtnsdnaa
       61 aggnadlsvq ltgsserwea vkddsgvlhl pgtgivtsng qyvlplqslq glqnqpillt
      121 sgtdasggav pniqyqvipq vqtadgqlgy savdgasmaq daagqiqilp dgtqtisvsg
      181 advlsstqnl mtqagqvhqi pqvslgsstf stqgqvvtnv plglpgnitf vpinsldlds
      241 lglsgaqpia tsvtadgqli mtnqsvense gsakageqqq tlnssaaadm fvpttsssss
      301 qqhtgtidsm geqgdgsgyl sqvsggqqvi qlqqlpfqta dgqvsaqaqq slqnvqlinp
      361 gtfliqaqtv sasgqiqwqt fqvqgvqnlq nlqlqtapaq qitlapvqtl slgqggtpvs
      421 ltsgqmpnlq svsvnavgqa giqfqqsedt dstgdiqike epdseewpld ssstlnandl
      481 shlrvrlvee emegmnqegk rlrrvactcp nckegggrgs nmgkkkqhvc hiagcgkvyg
      541 ktshlrahlr whsgerpfvc twmfcgkrft rsdelqrhrr thtgekkfac secpkrfmrs
      601 dhlakhikth qnkkvvggam vasvggavss dsiittggtt liltniqpgt mqglatvsat
      661 vntsssqdql saaeiplqlv svsagdaae
//
LOCUS       XP_026128455             656 aa            linear   VRT 18-JUN-2025
DEFINITION  transcription factor Sp3 isoform X2 [Carassius auratus].
ACCESSION   XP_026128455
VERSION     XP_026128455.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272670.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..656
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..656
                     /product="transcription factor Sp3 isoform X2"
                     /calculated_mol_wt=67856
     Region          22..496
                     /region_name="SP1-4_N"
                     /note="N-terminal domain of transcription factor
                     Specificity Proteins (SP) 1-4; cl41773"
                     /db_xref="CDD:425404"
     Region          495..519
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          497..519
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(504,506,508,510..511,514..515,518,534,536,540..541,
                     544..545,548,562,564,566,568..569,572..573,576)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          525..549
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          527..549
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          541..564
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          555..577
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          557..577
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..656
                     /gene="sp3a"
                     /coded_by="XM_026272670.1:173..2143"
                     /db_xref="GeneID:113109114"
ORIGIN      
        1 mtapegpvka gvmadsssaq dggaeqdgqp sslallaatc tglgspapgp enrtnsdnaa
       61 aggnadlsvq ltgsserwea vkddsgvlhl pgtgivtsng qyvlplqslq glqnqpillt
      121 sgtdasggav pniqyqvipq vqtadgqlgy savdgasmaq daagqiqilp dgtqtisvsg
      181 advlsstqnl mtqagqvhqi pqvslgsstf stqgqvvtnv plglpgnitf vpinsldlds
      241 lglsgaqpia tsvtadgqli mtnqsvense gsakageqqq tlnssaaadm fvpttsssss
      301 qqhtgtidsm geqgdgsgyl sqvsggqqvi qlqqlpfqta dgqvsaqaqq slqnvqlinp
      361 gtfliqaqtv sasgqiqwqt fqvqgvqnlq nlqlqtapaq qitlapvqtl slgqggtpvs
      421 ltsgqmpnlq svsvnavgqa giqfqqsedt dstgveeeme gmnqegkrlr rvactcpnck
      481 egggrgsnmg kkkqhvchia gcgkvygkts hlrahlrwhs gerpfvctwm fcgkrftrsd
      541 elqrhrrtht gekkfacsec pkrfmrsdhl akhikthqnk kvvggamvas vggavssdsi
      601 ittggttlil tniqpgtmqg latvsatvnt sssqdqlsaa eiplqlvsvs agdaae
//
LOCUS       XP_026128456             791 aa            linear   VRT 18-JUN-2025
DEFINITION  mitogen-activated protein kinase kinase kinase 20-like [Carassius
            auratus].
ACCESSION   XP_026128456
VERSION     XP_026128456.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272671.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..791
                     /product="mitogen-activated protein kinase kinase kinase
                     20-like"
                     /calculated_mol_wt=90090
     Region          22..263
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(22..25,28,30,43,45,66,82..85,133,137..138,140,
                     150..151)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     Region          338..405
                     /region_name="SAM_MLTK"
                     /note="SAM domain of MLTK subfamily; cd09529"
                     /db_xref="CDD:188928"
     CDS             1..791
                     /gene="LOC113109115"
                     /coded_by="XM_026272671.1:148..2523"
                     /db_xref="GeneID:113109115"
ORIGIN      
        1 maslgasfvq irfddilfye ncgggsfgsv yrarwlsqdk evavkkllki ekeaeilsvl
       61 shrniiqfyg aileapnygi vteyasggsl fdylssaese dismkqimtw amdiakgmhy
      121 lhaeapftvi hrdlksrnvv ltadsvlkic dfgaskfhsh tthmslvgtf pwmapeviqs
      181 lpasetcdty sygvvlweml treipfkgle glqvawlvve kserltipss cpdsfaclmr
      241 scwltepkdr plfkhilstl esmwsdshlp eecdtflhsk aewrceieat lerlkrlerd
      301 lstkeqelke rerrlkmwer klieqsntpl lpnlaihswt eehvhfwmeq ifqgdgelqq
      361 yaeifrqnhi tgqrllllse tdmrdlgvts kghiihlkte ieklthdymn lfhfpplikd
      421 glsteeaeee wrktvnlelv fgyhwkagtg qsdckwkmym eldgdevaia yikdvtfnan
      481 rpdadvlkmt kppfvmdkwi lgisgtqtvd civnyegnvr spkctrhehr vqwspdsgrd
      541 virpvellie ttpntreghn rsrsnsgvdp rwiyslrmkq wreqaaqest gkrtlpqfls
      601 vignqssyaa avrrspnrsp ltpwtdsrss sptlsvklsn ilpgskgssp ssttsestse
      661 rerppsggaq hhyhrkayyd ntfkmngger gevearrtnq msqrgsrgfq hagrprnnns
      721 yitpsnhqpr tipgmsvvse gvkqkeagsg dgdwikverk ksikqehkhq evrqgrgrpr
      781 rggrgggrgr s
//
LOCUS       XP_026128457             412 aa            linear   VRT 18-JUN-2025
DEFINITION  cell division cycle-associated protein 7 [Carassius auratus].
ACCESSION   XP_026128457
VERSION     XP_026128457.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272672.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..412
                     /product="cell division cycle-associated protein 7"
                     /calculated_mol_wt=46423
     Region          <103..>240
                     /region_name="PTZ00449"
                     /note="104 kDa microneme/rhoptry antigen; Provisional"
                     /db_xref="CDD:185628"
     Region          308..401
                     /region_name="zf-4CXXC_R1"
                     /note="Zinc-finger domain of monoamine-oxidase A repressor
                     R1; pfam10497"
                     /db_xref="CDD:463117"
     CDS             1..412
                     /gene="LOC113109116"
                     /coded_by="XM_026272672.1:142..1380"
                     /db_xref="GeneID:113109116"
ORIGIN      
        1 mrskreqarc spstrmnlrs yrstallpme tssssddscd sfgsdgfgts krplrqtrss
       61 apsekvfnil pvteeedacs gfendlnedm temkmdsdse acspprktrk sftlrvamkf
      121 pnkraspskp vspeskpesk pkpepkdpes dsegdnfmlk ralnirenka mlaklmseld
      181 kvpgliprka alsqgntprr vprrsldasg arrrnperts rphtrsrslv dgppspaped
      241 dpedkyslvr rnrsddddye eereprrrsy nsaltiphvv rpveeiteae ldnicvnare
      301 ktynratgst chqcrqkttd tktncrnpec vgvrgqfcgp clknrygedv rdallnpewl
      361 cppcrgicnc sfcraregrc atgvlvylak yhgydnvhsy lkslkkeleq se
//
LOCUS       XP_026128458            1029 aa            linear   VRT 18-JUN-2025
DEFINITION  rap guanine nucleotide exchange factor 4 isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128458
VERSION     XP_026128458.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272673.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1029
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1029
                     /product="rap guanine nucleotide exchange factor 4 isoform
                     X1"
                     /calculated_mol_wt=117668
     Region          53..162
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(124..125,133..135)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(155..157,161..162)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     Region          230..358
                     /region_name="DEP_Epac"
                     /note="DEP (Dishevelled, Egl-10, and Pleckstrin) domain
                     found in Epac-like proteins. Epac (exchange proteins
                     directly activated by cAMP) proteins are GEFs
                     (guanine-nucleotide-exchange factors) for the small
                     GTPases, Rap1 and Rap2. They are directly regulated by...;
                     cd04437"
                     /db_xref="CDD:239884"
     Region          380..491
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(446..447,456..458)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(479..481,485..487)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     Region          522..646
                     /region_name="REM"
                     /note="Guanine nucleotide exchange factor for Ras-like
                     GTPases; N-terminal domain (RasGef_N), also called REM
                     domain (Ras exchanger motif). This domain is common in
                     nucleotide exchange factors for Ras-like small GTPases and
                     is typically found immediately...; cd06224"
                     /db_xref="CDD:100121"
     Site            order(533,588,592..593,596,599..600,635..636,639,646)
                     /site_type="other"
                     /note="GTPase interaction site [polypeptide binding]"
                     /db_xref="CDD:100121"
     Region          785..1027
                     /region_name="RasGEF"
                     /note="Guanine nucleotide exchange factor for Ras-like
                     small GTPases; smart00147"
                     /db_xref="CDD:214539"
     Site            order(818..820,830..831,833..835,837..838,841..842,845,
                     878,881..882,884..886,888..891,893..894,914,917,922..924,
                     927,940..942,945..947,949..951,953..956,970,974,1015,
                     1018..1019)
                     /site_type="other"
                     /note="Ras interaction site [polypeptide binding]"
                     /db_xref="CDD:238087"
     CDS             1..1029
                     /gene="LOC113109117"
                     /coded_by="XM_026272673.1:72..3161"
                     /db_xref="GeneID:113109117"
ORIGIN      
        1 mircmisqkm vaahtsshps asaewiicld krpeersged vdiilarlkr vkafekfhps
       61 llqqiclrgf ceclekgitl yrqgdigtnw ytvlsgsldv kvsetanhqd avtictlgig
      121 tafgesildn tprhativtr efsellrieq rdfrslwesy rqcmagllvp pygvmesiph
      181 tdrmpdkenl dhgspgsssk hlnkksfiqs ptklhpksia qvpsgkilra gkvlritils
      241 raphmirdrk yhlktyrqcc igtelvdwlm qhtscvhsrv qavgmwqvll eegvlnhvdq
      301 elsfqdkylf yrfledeted aplpneeekk esdeelqdtl lllsqigpda hlrmilrkqp
      361 gqrtvddlei iyeellhika lshlsttvkr elaavlifes hakagtvlfn qgeegtswyi
      421 ilkgsvnvvi ygkgvvctlh egddfgklal vndapraasi vlrednchfl rvdkedfnrv
      481 lrdveantvr lkeheedvlv lektnnrast ssplkytvms gtpekilehl lettkldsqf
      541 tesdpalddf llmhcvfvpn sqlcpllmah yhsqssqgse qermdyslnn krrvirlvlq
      601 waaintdhlq eedssfhflq efyetvfeds rlipalkeql pelekiikqn cddgrpsqkk
      661 hkvllrqfst gndrlqkkqp ikstdeilfk vycsdhtyst irvpvaasvr evitavtdkl
      721 gsgddlllih lnsagdkell kpsdvsifss lsingrlfvs prdqidsltp lpeqegpsag
      781 smstfelmss kdlahqmtly dwelfgcvhe heliyhtfgr qhfkkttanl dlflrrfnev
      841 qlwvvtevcl cptlskrvql lkkfikiaah ckefknlnsf faiimglgnp avcrlsqtwe
      901 klpskfkkfy gefenlmdps rnhrayrltv akleppiipf mpllikdmtf thegnktftd
      961 rlvnfekmrm iantvrimry crsqpfsqea pqatgkshqd vrsyvrhisv idnqrtlsql
     1021 shrleprrt
//
LOCUS       XP_026128459            1012 aa            linear   VRT 18-JUN-2025
DEFINITION  rap guanine nucleotide exchange factor 4 isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128459
VERSION     XP_026128459.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272674.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1012
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1012
                     /product="rap guanine nucleotide exchange factor 4 isoform
                     X2"
                     /calculated_mol_wt=115775
     Region          53..162
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(124..125,133..135)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(155..157,161..162)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     Region          213..341
                     /region_name="DEP_Epac"
                     /note="DEP (Dishevelled, Egl-10, and Pleckstrin) domain
                     found in Epac-like proteins. Epac (exchange proteins
                     directly activated by cAMP) proteins are GEFs
                     (guanine-nucleotide-exchange factors) for the small
                     GTPases, Rap1 and Rap2. They are directly regulated by...;
                     cd04437"
                     /db_xref="CDD:239884"
     Region          363..474
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(429..430,439..441)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(462..464,468..470)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     Region          505..629
                     /region_name="REM"
                     /note="Guanine nucleotide exchange factor for Ras-like
                     GTPases; N-terminal domain (RasGef_N), also called REM
                     domain (Ras exchanger motif). This domain is common in
                     nucleotide exchange factors for Ras-like small GTPases and
                     is typically found immediately...; cd06224"
                     /db_xref="CDD:100121"
     Site            order(516,571,575..576,579,582..583,618..619,622,629)
                     /site_type="other"
                     /note="GTPase interaction site [polypeptide binding]"
                     /db_xref="CDD:100121"
     Region          768..1010
                     /region_name="RasGEF"
                     /note="Guanine nucleotide exchange factor for Ras-like
                     small GTPases; smart00147"
                     /db_xref="CDD:214539"
     Site            order(801..803,813..814,816..818,820..821,824..825,828,
                     861,864..865,867..869,871..874,876..877,897,900,905..907,
                     910,923..925,928..930,932..934,936..939,953,957,998,
                     1001..1002)
                     /site_type="other"
                     /note="Ras interaction site [polypeptide binding]"
                     /db_xref="CDD:238087"
     CDS             1..1012
                     /gene="LOC113109117"
                     /coded_by="XM_026272674.1:73..3111"
                     /db_xref="GeneID:113109117"
ORIGIN      
        1 mircmisqkm vaahtsshps asaewiicld krpeersged vdiilarlkr vkafekfhps
       61 llqqiclrgf ceclekgitl yrqgdigtnw ytvlsgsldv kvsetanhqd avtictlgig
      121 tafgesildn tprhativtr efsellrieq rdfrslwesy rqcmagllvp pygvmesiph
      181 tdrmpdkenl dhgspgsssk hlnkvpsgki lragkvlrit ilsraphmir drkyhlktyr
      241 qccigtelvd wlmqhtscvh srvqavgmwq vlleegvlnh vdqelsfqdk ylfyrflede
      301 tedaplpnee ekkesdeelq dtllllsqig pdahlrmilr kqpgqrtvdd leiiyeellh
      361 ikalshlstt vkrelaavli feshakagtv lfnqgeegts wyiilkgsvn vviygkgvvc
      421 tlhegddfgk lalvndapra asivlrednc hflrvdkedf nrvlrdvean tvrlkeheed
      481 vlvlektnnr astssplkyt vmsgtpekil ehllettkld sqftesdpal ddfllmhcvf
      541 vpnsqlcpll mahyhsqssq gseqermdys lnnkrrvirl vlqwaaintd hlqeedssfh
      601 flqefyetvf edsrlipalk eqlpelekii kqncddgrps qkkhkvllrq fstgndrlqk
      661 kqpikstdei lfkvycsdht ystirvpvaa svrevitavt dklgsgddll lihlnsagdk
      721 ellkpsdvsi fsslsingrl fvsprdqids ltplpeqegp sagsmstfel msskdlahqm
      781 tlydwelfgc vheheliyht fgrqhfkktt anldlflrrf nevqlwvvte vclcptlskr
      841 vqllkkfiki aahckefknl nsffaiimgl gnpavcrlsq tweklpskfk kfygefenlm
      901 dpsrnhrayr ltvakleppi ipfmpllikd mtfthegnkt ftdrlvnfek mrmiantvri
      961 mrycrsqpfs qeapqatgks hqdvrsyvrh isvidnqrtl sqlshrlepr rt
//
LOCUS       XP_026128460             866 aa            linear   VRT 18-JUN-2025
DEFINITION  rap guanine nucleotide exchange factor 4 isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128460
VERSION     XP_026128460.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272675.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..866
                     /product="rap guanine nucleotide exchange factor 4 isoform
                     X3"
                     /calculated_mol_wt=99150
     Region          67..195
                     /region_name="DEP_Epac"
                     /note="DEP (Dishevelled, Egl-10, and Pleckstrin) domain
                     found in Epac-like proteins. Epac (exchange proteins
                     directly activated by cAMP) proteins are GEFs
                     (guanine-nucleotide-exchange factors) for the small
                     GTPases, Rap1 and Rap2. They are directly regulated by...;
                     cd04437"
                     /db_xref="CDD:239884"
     Region          217..328
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(283..284,293..295)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(316..318,322..324)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     Region          359..483
                     /region_name="REM"
                     /note="Guanine nucleotide exchange factor for Ras-like
                     GTPases; N-terminal domain (RasGef_N), also called REM
                     domain (Ras exchanger motif). This domain is common in
                     nucleotide exchange factors for Ras-like small GTPases and
                     is typically found immediately...; cd06224"
                     /db_xref="CDD:100121"
     Site            order(370,425,429..430,433,436..437,472..473,476,483)
                     /site_type="other"
                     /note="GTPase interaction site [polypeptide binding]"
                     /db_xref="CDD:100121"
     Region          622..864
                     /region_name="RasGEF"
                     /note="Guanine nucleotide exchange factor for Ras-like
                     small GTPases; smart00147"
                     /db_xref="CDD:214539"
     Site            order(655..657,667..668,670..672,674..675,678..679,682,
                     715,718..719,721..723,725..728,730..731,751,754,759..761,
                     764,777..779,782..784,786..788,790..793,807,811,852,
                     855..856)
                     /site_type="other"
                     /note="Ras interaction site [polypeptide binding]"
                     /db_xref="CDD:238087"
     CDS             1..866
                     /gene="LOC113109117"
                     /coded_by="XM_026272675.1:185..2785"
                     /db_xref="GeneID:113109117"
ORIGIN      
        1 magllvppyg vmesiphtdr mpdkenldhg spgssskhln kksfiqsptk lhpksiaqvp
       61 sgkilragkv lritilsrap hmirdrkyhl ktyrqccigt elvdwlmqht scvhsrvqav
      121 gmwqvlleeg vlnhvdqels fqdkylfyrf ledetedapl pneeekkesd eelqdtllll
      181 sqigpdahlr milrkqpgqr tvddleiiye ellhikalsh lsttvkrela avlifeshak
      241 agtvlfnqge egtswyiilk gsvnvviygk gvvctlhegd dfgklalvnd apraasivlr
      301 ednchflrvd kedfnrvlrd veantvrlke heedvlvlek tnnrastssp lkytvmsgtp
      361 ekilehllet tkldsqftes dpalddfllm hcvfvpnsql cpllmahyhs qssqgseqer
      421 mdyslnnkrr virlvlqwaa intdhlqeed ssfhflqefy etvfedsrli palkeqlpel
      481 ekiikqncdd grpsqkkhkv llrqfstgnd rlqkkqpiks tdeilfkvyc sdhtystirv
      541 pvaasvrevi tavtdklgsg ddlllihlns agdkellkps dvsifsslsi ngrlfvsprd
      601 qidsltplpe qegpsagsms tfelmsskdl ahqmtlydwe lfgcvhehel iyhtfgrqhf
      661 kkttanldlf lrrfnevqlw vvtevclcpt lskrvqllkk fikiaahcke fknlnsffai
      721 imglgnpavc rlsqtweklp skfkkfygef enlmdpsrnh rayrltvakl eppiipfmpl
      781 likdmtfthe gnktftdrlv nfekmrmian tvrimrycrs qpfsqeapqa tgkshqdvrs
      841 yvrhisvidn qrtlsqlshr leprrt
//
LOCUS       XP_026128461             866 aa            linear   VRT 18-JUN-2025
DEFINITION  rap guanine nucleotide exchange factor 4 isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128461
VERSION     XP_026128461.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272676.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..866
                     /product="rap guanine nucleotide exchange factor 4 isoform
                     X3"
                     /calculated_mol_wt=99150
     Region          67..195
                     /region_name="DEP_Epac"
                     /note="DEP (Dishevelled, Egl-10, and Pleckstrin) domain
                     found in Epac-like proteins. Epac (exchange proteins
                     directly activated by cAMP) proteins are GEFs
                     (guanine-nucleotide-exchange factors) for the small
                     GTPases, Rap1 and Rap2. They are directly regulated by...;
                     cd04437"
                     /db_xref="CDD:239884"
     Region          217..328
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(283..284,293..295)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(316..318,322..324)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     Region          359..483
                     /region_name="REM"
                     /note="Guanine nucleotide exchange factor for Ras-like
                     GTPases; N-terminal domain (RasGef_N), also called REM
                     domain (Ras exchanger motif). This domain is common in
                     nucleotide exchange factors for Ras-like small GTPases and
                     is typically found immediately...; cd06224"
                     /db_xref="CDD:100121"
     Site            order(370,425,429..430,433,436..437,472..473,476,483)
                     /site_type="other"
                     /note="GTPase interaction site [polypeptide binding]"
                     /db_xref="CDD:100121"
     Region          622..864
                     /region_name="RasGEF"
                     /note="Guanine nucleotide exchange factor for Ras-like
                     small GTPases; smart00147"
                     /db_xref="CDD:214539"
     Site            order(655..657,667..668,670..672,674..675,678..679,682,
                     715,718..719,721..723,725..728,730..731,751,754,759..761,
                     764,777..779,782..784,786..788,790..793,807,811,852,
                     855..856)
                     /site_type="other"
                     /note="Ras interaction site [polypeptide binding]"
                     /db_xref="CDD:238087"
     CDS             1..866
                     /gene="LOC113109117"
                     /coded_by="XM_026272676.1:185..2785"
                     /db_xref="GeneID:113109117"
ORIGIN      
        1 magllvppyg vmesiphtdr mpdkenldhg spgssskhln kksfiqsptk lhpksiaqvp
       61 sgkilragkv lritilsrap hmirdrkyhl ktyrqccigt elvdwlmqht scvhsrvqav
      121 gmwqvlleeg vlnhvdqels fqdkylfyrf ledetedapl pneeekkesd eelqdtllll
      181 sqigpdahlr milrkqpgqr tvddleiiye ellhikalsh lsttvkrela avlifeshak
      241 agtvlfnqge egtswyiilk gsvnvviygk gvvctlhegd dfgklalvnd apraasivlr
      301 ednchflrvd kedfnrvlrd veantvrlke heedvlvlek tnnrastssp lkytvmsgtp
      361 ekilehllet tkldsqftes dpalddfllm hcvfvpnsql cpllmahyhs qssqgseqer
      421 mdyslnnkrr virlvlqwaa intdhlqeed ssfhflqefy etvfedsrli palkeqlpel
      481 ekiikqncdd grpsqkkhkv llrqfstgnd rlqkkqpiks tdeilfkvyc sdhtystirv
      541 pvaasvrevi tavtdklgsg ddlllihlns agdkellkps dvsifsslsi ngrlfvsprd
      601 qidsltplpe qegpsagsms tfelmsskdl ahqmtlydwe lfgcvhehel iyhtfgrqhf
      661 kkttanldlf lrrfnevqlw vvtevclcpt lskrvqllkk fikiaahcke fknlnsffai
      721 imglgnpavc rlsqtweklp skfkkfygef enlmdpsrnh rayrltvakl eppiipfmpl
      781 likdmtfthe gnktftdrlv nfekmrmian tvrimrycrs qpfsqeapqa tgkshqdvrs
      841 yvrhisvidn qrtlsqlshr leprrt
//
LOCUS       XP_026128462            1354 aa            linear   VRT 18-JUN-2025
DEFINITION  neurabin-1-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128462
VERSION     XP_026128462.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272677.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1354
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1354
                     /product="neurabin-1-like isoform X1"
                     /calculated_mol_wt=150922
     Region          92..>399
                     /region_name="DUF5585"
                     /note="Family of unknown function (DUF5585); pfam17823"
                     /db_xref="CDD:465521"
     Region          559..613
                     /region_name="PDZ_5"
                     /note="PDZ domain; pfam17817"
                     /db_xref="CDD:465518"
     Region          617..706
                     /region_name="PDZ_neurabin-like"
                     /note="PDZ domain of neurabin-1 and neurabin-2, and
                     related domains; cd06790"
                     /db_xref="CDD:467252"
     Site            order(629..635,653,656,686,690,693..694)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467252"
     Region          <762..>1132
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          790..>926
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     Region          1256..1315
                     /region_name="SAM_Neurabin-like"
                     /note="SAM domain of SAM_Neurabin-like subfamily; cd09512"
                     /db_xref="CDD:188911"
     CDS             1..1354
                     /gene="LOC113109118"
                     /coded_by="XM_026272677.1:251..4315"
                     /db_xref="GeneID:113109118"
ORIGIN      
        1 mikaeskger tlrsasphrn ayksdfhaik csfdgtksds edksyangas dlredtrgrp
       61 fgnrvskikn iflqmdgqqp pesqepaykt dasspvspvs kfpvsthktc lssannqepq
      121 ntdrtpkgee veidkaalae kfsvtrklfe rgikeqpaad kpgpgrvstr lsqgkvpeeg
      181 rgarrsfgss ennnssviqs ptsptrsape erretedskq vsrlslnsgp vskrlenftv
      241 dgnkedsmqs peklsspter slpsprgsfq kpsspaadpe hkptspnsdk llpktnsssp
      301 pfksispisy kptsptsrtp geplspnaqs pssgnhsvkd stineapqhs stpakdlkas
      361 psasgtykrp wspeepkspn hiirspsrdi ykeqvaqsld pagagvvrae lvvvqnesse
      421 seendeelle evklqrelkl eaqrkdvtas lqvsspqnht edkqlekdac vstelkkeep
      481 nqeeeeeeee eeiiqkrnsc hedddeeese qedpdecgkt spvfysfena afvddkepgq
      541 dqqdeedede vyeeydeapg lcedeegppr rkirfstepi rvystfsnee ydrrnddvdp
      601 vaasaeyele krvekmdvfp veiekgdkgl gisiigmgvg adqgleklgi fvktitqdga
      661 aerdgriqvn dqivevdgis lvgvtqlfaa tvlkntkgtv rfligrekpg vqsevarlis
      721 etleqerqqq qvddtyevst eedehyedee eegilgssfg rrnvevydlp eseemflpsd
      781 mdaaqltfrf kelqikhtia eaevdelker lreaseeraa weareaqler svqenserma
      841 qmeknwleaq alcksideql ndtqsqyeal dkkyskakkl lkdyqqkeae yeqreedlrr
      901 sleereaeyk thiedlqrrl aqlesespls gsksadsvll gadwsevvpe terldtsvhr
      961 akaqlaqrsk rqppsrsklk etlsspvrsp qdddesqsvs pesppprrrs vqeslslpva
     1021 isspanhqkd egsvtsssqs vqrdpqspal sspkdsspss flrnvkkres kgkgkevkde
     1081 sndaagktrr rfpdfgglrk sggkgkklsk eatrasldsr gsaelleesg arvspsesmt
     1141 siptcmpfsw fgekdkerdr dpsssssslp htaadehshs sknktnlsws slfsrsldls
     1201 lsvlddsnps spasdfsglv lepnlsgrsh tltfssseml ddeepcsggk eyhwqnrpvs
     1261 dwtsqqvchw lmgmnmdqyt pefstqaidg qqllnldsdr lkalgvssqn dratikkklk
     1321 emkkaqekme kqrekrekea rrsgrlpast dsvc
//
LOCUS       XP_026128463            1353 aa            linear   VRT 18-JUN-2025
DEFINITION  neurabin-1-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128463
VERSION     XP_026128463.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272678.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1353
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1353
                     /product="neurabin-1-like isoform X2"
                     /calculated_mol_wt=150865
     Region          92..>399
                     /region_name="DUF5585"
                     /note="Family of unknown function (DUF5585); pfam17823"
                     /db_xref="CDD:465521"
     Region          559..613
                     /region_name="PDZ_5"
                     /note="PDZ domain; pfam17817"
                     /db_xref="CDD:465518"
     Region          617..706
                     /region_name="PDZ_neurabin-like"
                     /note="PDZ domain of neurabin-1 and neurabin-2, and
                     related domains; cd06790"
                     /db_xref="CDD:467252"
     Site            order(629..635,653,656,686,690,693..694)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467252"
     Region          <765..>1131
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          790..>926
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     Region          1255..1314
                     /region_name="SAM_Neurabin-like"
                     /note="SAM domain of SAM_Neurabin-like subfamily; cd09512"
                     /db_xref="CDD:188911"
     CDS             1..1353
                     /gene="LOC113109118"
                     /coded_by="XM_026272678.1:251..4312"
                     /db_xref="GeneID:113109118"
ORIGIN      
        1 mikaeskger tlrsasphrn ayksdfhaik csfdgtksds edksyangas dlredtrgrp
       61 fgnrvskikn iflqmdgqqp pesqepaykt dasspvspvs kfpvsthktc lssannqepq
      121 ntdrtpkgee veidkaalae kfsvtrklfe rgikeqpaad kpgpgrvstr lsqgkvpeeg
      181 rgarrsfgss ennnssviqs ptsptrsape erretedskq vsrlslnsgp vskrlenftv
      241 dgnkedsmqs peklsspter slpsprgsfq kpsspaadpe hkptspnsdk llpktnsssp
      301 pfksispisy kptsptsrtp geplspnaqs pssgnhsvkd stineapqhs stpakdlkas
      361 psasgtykrp wspeepkspn hiirspsrdi ykeqvaqsld pagagvvrae lvvvqnesse
      421 seendeelle evklqrelkl eaqrkdvtas lqvsspqnht edkqlekdac vstelkkeep
      481 nqeeeeeeee eeiiqkrnsc hedddeeese qedpdecgkt spvfysfena afvddkepgq
      541 dqqdeedede vyeeydeapg lcedeegppr rkirfstepi rvystfsnee ydrrnddvdp
      601 vaasaeyele krvekmdvfp veiekgdkgl gisiigmgvg adqgleklgi fvktitqdga
      661 aerdgriqvn dqivevdgis lvgvtqlfaa tvlkntkgtv rfligrekpg vqsevarlis
      721 etleqerqqq qvddtyevst eedehyedee eegilgssfg rrnvevydlp eseemflpsd
      781 mdaaqltfrf kelqikhtia eaevdelker lreaseeraa weareaqler svqenserma
      841 qmeknwleaq alcksideql ndtqsqyeal dkkyskakkl lkdyqqkeae yeqreedlrr
      901 sleereaeyk thiedlqrrl aqlesespls gsksadsvll gadwsevvpe terldtsvhr
      961 akaqlaqrsk rqppsrsklk etlsspvrsp qdddesqsvs pesppprrrs vqeslslpva
     1021 isspanhqkd egsvtsssqs vqrdpqspal sspkdsspss flrnvkkres kgkgkevkde
     1081 sndaagktrr rfpdfglrks ggkgkklske atrasldsrg saelleesga rvspsesmts
     1141 iptcmpfswf gekdkerdrd psssssslph taadehshss knktnlswss lfsrsldlsl
     1201 svlddsnpss pasdfsglvl epnlsgrsht ltfsssemld deepcsggke yhwqnrpvsd
     1261 wtsqqvchwl mgmnmdqytp efstqaidgq qllnldsdrl kalgvssqnd ratikkklke
     1321 mkkaqekmek qrekrekear rsgrlpastd svc
//
LOCUS       XP_026128464            1351 aa            linear   VRT 18-JUN-2025
DEFINITION  neurabin-1-like isoform X3 [Carassius auratus].
ACCESSION   XP_026128464
VERSION     XP_026128464.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272679.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1351
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1351
                     /product="neurabin-1-like isoform X3"
                     /calculated_mol_wt=150596
     Region          92..>399
                     /region_name="DUF5585"
                     /note="Family of unknown function (DUF5585); pfam17823"
                     /db_xref="CDD:465521"
     Region          559..613
                     /region_name="PDZ_5"
                     /note="PDZ domain; pfam17817"
                     /db_xref="CDD:465518"
     Region          617..706
                     /region_name="PDZ_neurabin-like"
                     /note="PDZ domain of neurabin-1 and neurabin-2, and
                     related domains; cd06790"
                     /db_xref="CDD:467252"
     Site            order(629..635,653,656,686,690,693..694)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467252"
     Region          790..>926
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     Region          1253..1312
                     /region_name="SAM_Neurabin-like"
                     /note="SAM domain of SAM_Neurabin-like subfamily; cd09512"
                     /db_xref="CDD:188911"
     CDS             1..1351
                     /gene="LOC113109118"
                     /coded_by="XM_026272679.1:251..4306"
                     /db_xref="GeneID:113109118"
ORIGIN      
        1 mikaeskger tlrsasphrn ayksdfhaik csfdgtksds edksyangas dlredtrgrp
       61 fgnrvskikn iflqmdgqqp pesqepaykt dasspvspvs kfpvsthktc lssannqepq
      121 ntdrtpkgee veidkaalae kfsvtrklfe rgikeqpaad kpgpgrvstr lsqgkvpeeg
      181 rgarrsfgss ennnssviqs ptsptrsape erretedskq vsrlslnsgp vskrlenftv
      241 dgnkedsmqs peklsspter slpsprgsfq kpsspaadpe hkptspnsdk llpktnsssp
      301 pfksispisy kptsptsrtp geplspnaqs pssgnhsvkd stineapqhs stpakdlkas
      361 psasgtykrp wspeepkspn hiirspsrdi ykeqvaqsld pagagvvrae lvvvqnesse
      421 seendeelle evklqrelkl eaqrkdvtas lqvsspqnht edkqlekdac vstelkkeep
      481 nqeeeeeeee eeiiqkrnsc hedddeeese qedpdecgkt spvfysfena afvddkepgq
      541 dqqdeedede vyeeydeapg lcedeegppr rkirfstepi rvystfsnee ydrrnddvdp
      601 vaasaeyele krvekmdvfp veiekgdkgl gisiigmgvg adqgleklgi fvktitqdga
      661 aerdgriqvn dqivevdgis lvgvtqlfaa tvlkntkgtv rfligrekpg vqsevarlis
      721 etleqerqqq qvddtyevst eedehyedee eegilgssfg rrnvevydlp eseemflpsd
      781 mdaaqltfrf kelqikhtia eaevdelker lreaseeraa weareaqler svqenserma
      841 qmeknwleaq alcksideql ndtqsqyeal dkkyskakkl lkdyqqkeae yeqreedlrr
      901 sleereaeyk thiedlqrrl aqlesespls gsksadsvll gadwsevvpe terldtsvhr
      961 akaqlaqrsk rqppsrsklk etlsspvrsp qdddesqsvs pesppprrrs vqeslslpva
     1021 isspanhqkd egsvtsssqs vqrdpqspal sspkdsspss flrnvkkres kgkgkevkde
     1081 sndaagktrr rfpdfgksgg kgkklskeat rasldsrgsa elleesgarv spsesmtsip
     1141 tcmpfswfge kdkerdrdps ssssslphta adehshsskn ktnlswsslf srsldlslsv
     1201 lddsnpsspa sdfsglvlep nlsgrshtlt fsssemldde epcsggkeyh wqnrpvsdwt
     1261 sqqvchwlmg mnmdqytpef stqaidgqql lnldsdrlka lgvssqndra tikkklkemk
     1321 kaqekmekqr ekrekearrs grlpastdsv c
//
LOCUS       XP_026128465            1349 aa            linear   VRT 18-JUN-2025
DEFINITION  neurabin-1-like isoform X4 [Carassius auratus].
ACCESSION   XP_026128465
VERSION     XP_026128465.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272680.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1349
                     /product="neurabin-1-like isoform X4"
                     /calculated_mol_wt=150354
     Region          92..>399
                     /region_name="DUF5585"
                     /note="Family of unknown function (DUF5585); pfam17823"
                     /db_xref="CDD:465521"
     Region          559..613
                     /region_name="PDZ_5"
                     /note="PDZ domain; pfam17817"
                     /db_xref="CDD:465518"
     Region          617..706
                     /region_name="PDZ_neurabin-like"
                     /note="PDZ domain of neurabin-1 and neurabin-2, and
                     related domains; cd06790"
                     /db_xref="CDD:467252"
     Site            order(629..635,653,656,686,690,693..694)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467252"
     Region          <765..>1127
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          790..>926
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     Region          1251..1310
                     /region_name="SAM_Neurabin-like"
                     /note="SAM domain of SAM_Neurabin-like subfamily; cd09512"
                     /db_xref="CDD:188911"
     CDS             1..1349
                     /gene="LOC113109118"
                     /coded_by="XM_026272680.1:251..4300"
                     /db_xref="GeneID:113109118"
ORIGIN      
        1 mikaeskger tlrsasphrn ayksdfhaik csfdgtksds edksyangas dlredtrgrp
       61 fgnrvskikn iflqmdgqqp pesqepaykt dasspvspvs kfpvsthktc lssannqepq
      121 ntdrtpkgee veidkaalae kfsvtrklfe rgikeqpaad kpgpgrvstr lsqgkvpeeg
      181 rgarrsfgss ennnssviqs ptsptrsape erretedskq vsrlslnsgp vskrlenftv
      241 dgnkedsmqs peklsspter slpsprgsfq kpsspaadpe hkptspnsdk llpktnsssp
      301 pfksispisy kptsptsrtp geplspnaqs pssgnhsvkd stineapqhs stpakdlkas
      361 psasgtykrp wspeepkspn hiirspsrdi ykeqvaqsld pagagvvrae lvvvqnesse
      421 seendeelle evklqrelkl eaqrkdvtas lqvsspqnht edkqlekdac vstelkkeep
      481 nqeeeeeeee eeiiqkrnsc hedddeeese qedpdecgkt spvfysfena afvddkepgq
      541 dqqdeedede vyeeydeapg lcedeegppr rkirfstepi rvystfsnee ydrrnddvdp
      601 vaasaeyele krvekmdvfp veiekgdkgl gisiigmgvg adqgleklgi fvktitqdga
      661 aerdgriqvn dqivevdgis lvgvtqlfaa tvlkntkgtv rfligrekpg vqsevarlis
      721 etleqerqqq qvddtyevst eedehyedee eegilgssfg rrnvevydlp eseemflpsd
      781 mdaaqltfrf kelqikhtia eaevdelker lreaseeraa weareaqler svqenserma
      841 qmeknwleaq alcksideql ndtqsqyeal dkkyskakkl lkdyqqkeae yeqreedlrr
      901 sleereaeyk thiedlqrrl aqlesespls gsksadsvll gadwsevvpe terldtsvhr
      961 akaqlaqrsk rqppsrsklk etlsspddde sqsvspespp prrrsvqesl slpvaisspa
     1021 nhqkdegsvt sssqsvqrdp qspalsspkd sspssflrnv kkreskgkgk evkdesndaa
     1081 gktrrrfpdf gglrksggkg kklskeatra sldsrgsael leesgarvsp sesmtsiptc
     1141 mpfswfgekd kerdrdpsss ssslphtaad ehshssknkt nlswsslfsr sldlslsvld
     1201 dsnpsspasd fsglvlepnl sgrshtltfs ssemlddeep csggkeyhwq nrpvsdwtsq
     1261 qvchwlmgmn mdqytpefst qaidgqqlln ldsdrlkalg vssqndrati kkklkemkka
     1321 qekmekqrek rekearrsgr lpastdsvc
//
LOCUS       XP_026128466            1339 aa            linear   VRT 18-JUN-2025
DEFINITION  neurabin-1-like isoform X5 [Carassius auratus].
ACCESSION   XP_026128466
VERSION     XP_026128466.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272681.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1339
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1339
                     /product="neurabin-1-like isoform X5"
                     /calculated_mol_wt=149214
     Region          92..>399
                     /region_name="DUF5585"
                     /note="Family of unknown function (DUF5585); pfam17823"
                     /db_xref="CDD:465521"
     Region          559..613
                     /region_name="PDZ_5"
                     /note="PDZ domain; pfam17817"
                     /db_xref="CDD:465518"
     Region          617..706
                     /region_name="PDZ_neurabin-like"
                     /note="PDZ domain of neurabin-1 and neurabin-2, and
                     related domains; cd06790"
                     /db_xref="CDD:467252"
     Site            order(629..635,653,656,686,690,693..694)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467252"
     Region          <765..>1132
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          790..>926
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     Region          1241..1300
                     /region_name="SAM_Neurabin-like"
                     /note="SAM domain of SAM_Neurabin-like subfamily; cd09512"
                     /db_xref="CDD:188911"
     CDS             1..1339
                     /gene="LOC113109118"
                     /coded_by="XM_026272681.1:251..4270"
                     /db_xref="GeneID:113109118"
ORIGIN      
        1 mikaeskger tlrsasphrn ayksdfhaik csfdgtksds edksyangas dlredtrgrp
       61 fgnrvskikn iflqmdgqqp pesqepaykt dasspvspvs kfpvsthktc lssannqepq
      121 ntdrtpkgee veidkaalae kfsvtrklfe rgikeqpaad kpgpgrvstr lsqgkvpeeg
      181 rgarrsfgss ennnssviqs ptsptrsape erretedskq vsrlslnsgp vskrlenftv
      241 dgnkedsmqs peklsspter slpsprgsfq kpsspaadpe hkptspnsdk llpktnsssp
      301 pfksispisy kptsptsrtp geplspnaqs pssgnhsvkd stineapqhs stpakdlkas
      361 psasgtykrp wspeepkspn hiirspsrdi ykeqvaqsld pagagvvrae lvvvqnesse
      421 seendeelle evklqrelkl eaqrkdvtas lqvsspqnht edkqlekdac vstelkkeep
      481 nqeeeeeeee eeiiqkrnsc hedddeeese qedpdecgkt spvfysfena afvddkepgq
      541 dqqdeedede vyeeydeapg lcedeegppr rkirfstepi rvystfsnee ydrrnddvdp
      601 vaasaeyele krvekmdvfp veiekgdkgl gisiigmgvg adqgleklgi fvktitqdga
      661 aerdgriqvn dqivevdgis lvgvtqlfaa tvlkntkgtv rfligrekpg vqsevarlis
      721 etleqerqqq qvddtyevst eedehyedee eegilgssfg rrnvevydlp eseemflpsd
      781 mdaaqltfrf kelqikhtia eaevdelker lreaseeraa weareaqler svqenserma
      841 qmeknwleaq alcksideql ndtqsqyeal dkkyskakkl lkdyqqkeae yeqreedlrr
      901 sleereaeyk thiedlqrrl aqlesespls gsksadsvll gadwsevvpe terldtsvhr
      961 akaqlaqrsk rqppsrsklk etlsspvrsp qdddesqsvs pesppprrrs vqeslslpva
     1021 isspanhqkd egsvtsssqs vqrdpqspal sspkdsspss flrnvkkres kgkgkevkde
     1081 sndaagktrr rfpdfgglrk sggkgkklsk eatrasldsr gsaelleesg arvspsesmt
     1141 siptcmpfsw fgekdkerdr dpsssssslp htaadehshs sknkslsvld dsnpsspasd
     1201 fsglvlepnl sgrshtltfs ssemlddeep csggkeyhwq nrpvsdwtsq qvchwlmgmn
     1261 mdqytpefst qaidgqqlln ldsdrlkalg vssqndrati kkklkemkka qekmekqrek
     1321 rekearrsgr lpastdsvc
//
LOCUS       XP_026128467            1300 aa            linear   VRT 18-JUN-2025
DEFINITION  neurabin-1-like isoform X6 [Carassius auratus].
ACCESSION   XP_026128467
VERSION     XP_026128467.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272682.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1300
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1300
                     /product="neurabin-1-like isoform X6"
                     /calculated_mol_wt=145194
     Region          92..>399
                     /region_name="DUF5585"
                     /note="Family of unknown function (DUF5585); pfam17823"
                     /db_xref="CDD:465521"
     Region          559..613
                     /region_name="PDZ_5"
                     /note="PDZ domain; pfam17817"
                     /db_xref="CDD:465518"
     Region          617..706
                     /region_name="PDZ_neurabin-like"
                     /note="PDZ domain of neurabin-1 and neurabin-2, and
                     related domains; cd06790"
                     /db_xref="CDD:467252"
     Site            order(629..635,653,656,686,690,693..694)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467252"
     Region          <765..>1132
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          790..>926
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     Region          1202..1261
                     /region_name="SAM_Neurabin-like"
                     /note="SAM domain of SAM_Neurabin-like subfamily; cd09512"
                     /db_xref="CDD:188911"
     CDS             1..1300
                     /gene="LOC113109118"
                     /coded_by="XM_026272682.1:251..4153"
                     /db_xref="GeneID:113109118"
ORIGIN      
        1 mikaeskger tlrsasphrn ayksdfhaik csfdgtksds edksyangas dlredtrgrp
       61 fgnrvskikn iflqmdgqqp pesqepaykt dasspvspvs kfpvsthktc lssannqepq
      121 ntdrtpkgee veidkaalae kfsvtrklfe rgikeqpaad kpgpgrvstr lsqgkvpeeg
      181 rgarrsfgss ennnssviqs ptsptrsape erretedskq vsrlslnsgp vskrlenftv
      241 dgnkedsmqs peklsspter slpsprgsfq kpsspaadpe hkptspnsdk llpktnsssp
      301 pfksispisy kptsptsrtp geplspnaqs pssgnhsvkd stineapqhs stpakdlkas
      361 psasgtykrp wspeepkspn hiirspsrdi ykeqvaqsld pagagvvrae lvvvqnesse
      421 seendeelle evklqrelkl eaqrkdvtas lqvsspqnht edkqlekdac vstelkkeep
      481 nqeeeeeeee eeiiqkrnsc hedddeeese qedpdecgkt spvfysfena afvddkepgq
      541 dqqdeedede vyeeydeapg lcedeegppr rkirfstepi rvystfsnee ydrrnddvdp
      601 vaasaeyele krvekmdvfp veiekgdkgl gisiigmgvg adqgleklgi fvktitqdga
      661 aerdgriqvn dqivevdgis lvgvtqlfaa tvlkntkgtv rfligrekpg vqsevarlis
      721 etleqerqqq qvddtyevst eedehyedee eegilgssfg rrnvevydlp eseemflpsd
      781 mdaaqltfrf kelqikhtia eaevdelker lreaseeraa weareaqler svqenserma
      841 qmeknwleaq alcksideql ndtqsqyeal dkkyskakkl lkdyqqkeae yeqreedlrr
      901 sleereaeyk thiedlqrrl aqlesespls gsksadsvll gadwsevvpe terldtsvhr
      961 akaqlaqrsk rqppsrsklk etlsspvrsp qdddesqsvs pesppprrrs vqeslslpva
     1021 isspanhqkd egsvtsssqs vqrdpqspal sspkdsspss flrnvkkres kgkgkevkde
     1081 sndaagktrr rfpdfgglrk sggkgkklsk eatrasldsr gsaelleesg arvspsesmt
     1141 siptcmpfsw fgekdkerdr dpsssssslp htaadehshs sknkmlddee pcsggkeyhw
     1201 qnrpvsdwts qqvchwlmgm nmdqytpefs tqaidgqqll nldsdrlkal gvssqndrat
     1261 ikkklkemkk aqekmekqre krekearrsg rlpastdsvc
//
LOCUS       XP_026128468             608 aa            linear   VRT 18-JUN-2025
DEFINITION  cytoplasmic dynein 1 intermediate chain 2-like isoform X1
            [Carassius auratus].
ACCESSION   XP_026128468
VERSION     XP_026128468.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272683.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..608
                     /product="cytoplasmic dynein 1 intermediate chain 2-like
                     isoform X1"
                     /calculated_mol_wt=67995
     Region          <55..182
                     /region_name="LGT"
                     /note="Prolipoprotein diacylglyceryl transferase; cl00478"
                     /db_xref="CDD:469786"
     Region          106..136
                     /region_name="Dynein_IC2"
                     /note="Cytoplasmic dynein 1 intermediate chain 2;
                     pfam11540"
                     /db_xref="CDD:463291"
     Region          251..568
                     /region_name="WD40"
                     /note="WD40 domain, found in a number of eukaryotic
                     proteins that cover a wide variety of functions including
                     adaptor/regulatory modules in signal transduction,
                     pre-mRNA processing and cytoskeleton assembly; typically
                     contains a GH dipeptide 11-24 residues from...; cl29593"
                     /db_xref="CDD:475233"
     Region          252..301
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Site            order(266,280,286..287,299..300,319,324,330..331,349..350,
                     369,374,380..381,400,419,423,444..445,469,473,479..480,
                     492..493,511,516,522..523,538..539,557,561,567..568)
                     /site_type="active"
                     /note="structural tetrad [active]"
                     /db_xref="CDD:238121"
     Region          306..345
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          354..397
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          405..453
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          460..491
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          497..534
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          541..567
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     CDS             1..608
                     /gene="LOC113109119"
                     /coded_by="XM_026272683.1:85..1911"
                     /db_xref="GeneID:113109119"
ORIGIN      
        1 msdkselkae lerkkqrlaq ireekkrkee erkkkeselk keavppqdds dlekkrread
       61 allqsmgitp dtpagptpms ptaksagsps eagsqdsgds apgprrgplk lamvkvtqvd
      121 fpprevvsyt ketqtptvte qkeeedeeee tappqpevet ekekpaekqd eeapphelte
      181 eeklqilhse efmeffdhst riveralseh vdvlfdysgr dveekegemq agtklslnrk
      241 fvddrwskqr vvtcldwspq ypellvasyn nneeaphepd gvalvwnmky kkttpeyvfh
      301 cqsavmsatf akfhpnlvvg gtysgqivlw dnrsnrrtpv qrtplsaaah thpvycvnvv
      361 gtqnahnlis istdgkmcsw sldmlsqpqd smelvfkqsk saavtsmsfp lgdvnnfvvg
      421 sedgsvytac rhgsragise mfeghhgpit gidchtaagp vdfshlflta sfdwtvklws
      481 tksnkplysf ednsdyvydv mwspvhptlf acvdglgrvd lwnlnndtev ptasvsveds
      541 palnrlrwsq sgreiavgds egqihiydvg eqiavprgde wtrfvrtlad ihenrddaee
      601 laaqrlaa
//
LOCUS       XP_026128469             612 aa            linear   VRT 18-JUN-2025
DEFINITION  cytoplasmic dynein 1 intermediate chain 2-like isoform X2
            [Carassius auratus].
ACCESSION   XP_026128469
VERSION     XP_026128469.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272684.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..612
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..612
                     /product="cytoplasmic dynein 1 intermediate chain 2-like
                     isoform X2"
                     /calculated_mol_wt=68452
     Region          <59..186
                     /region_name="LGT"
                     /note="Prolipoprotein diacylglyceryl transferase; cl00478"
                     /db_xref="CDD:469786"
     Region          110..140
                     /region_name="Dynein_IC2"
                     /note="Cytoplasmic dynein 1 intermediate chain 2;
                     pfam11540"
                     /db_xref="CDD:463291"
     Region          255..572
                     /region_name="WD40"
                     /note="WD40 domain, found in a number of eukaryotic
                     proteins that cover a wide variety of functions including
                     adaptor/regulatory modules in signal transduction,
                     pre-mRNA processing and cytoskeleton assembly; typically
                     contains a GH dipeptide 11-24 residues from...; cl29593"
                     /db_xref="CDD:475233"
     Region          256..305
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Site            order(270,284,290..291,303..304,323,328,334..335,353..354,
                     373,378,384..385,404,423,427,448..449,473,477,483..484,
                     496..497,515,520,526..527,542..543,561,565,571..572)
                     /site_type="active"
                     /note="structural tetrad [active]"
                     /db_xref="CDD:238121"
     Region          310..349
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          358..401
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          409..457
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          464..495
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          501..538
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          545..571
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     CDS             1..612
                     /gene="LOC113109119"
                     /coded_by="XM_026272684.1:373..2211"
                     /db_xref="GeneID:113109119"
ORIGIN      
        1 mviimsdkse lkaelerkkq rlaqireekk rkeeerkkke selkkeavpp qddsdlekkr
       61 readallqsm gitpdtpagp tpmsptaksa gspseagsqd sgdsapgprr gplklamvkv
      121 tqvdfpprev vsytketqtp tvteqkeeed eeeetappqp evetekekpa ekqdeeapph
      181 elteeeklqi lhseefmeff dhstrivera lsehvdvlfd ysgrdveeke gemqagtkls
      241 lnrkfvddrw skqrvvtcld wspqypellv asynnneeap hepdgvalvw nmkykkttpe
      301 yvfhcqsavm satfakfhpn lvvggtysgq ivlwdnrsnr rtpvqrtpls aaahthpvyc
      361 vnvvgtqnah nlisistdgk mcswsldmls qpqdsmelvf kqsksaavts msfplgdvnn
      421 fvvgsedgsv ytacrhgsra gisemfeghh gpitgidcht aagpvdfshl fltasfdwtv
      481 klwstksnkp lysfednsdy vydvmwspvh ptlfacvdgl grvdlwnlnn dtevptasvs
      541 vedspalnrl rwsqsgreia vgdsegqihi ydvgeqiavp rgdewtrfvr tladihenrd
      601 daeelaaqrl aa
//
LOCUS       XP_026128470             408 aa            linear   VRT 18-JUN-2025
DEFINITION  histone acetyltransferase type B catalytic subunit-like [Carassius
            auratus].
ACCESSION   XP_026128470
VERSION     XP_026128470.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272685.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..408
                     /product="histone acetyltransferase type B catalytic
                     subunit-like"
                     /calculated_mol_wt=47610
     Region          14..176
                     /region_name="Hat1_N"
                     /note="Histone acetyl transferase HAT1 N-terminus;
                     pfam10394"
                     /db_xref="CDD:463071"
     CDS             1..408
                     /gene="LOC113109120"
                     /coded_by="XM_026272685.1:90..1316"
                     /db_xref="GeneID:113109120"
ORIGIN      
        1 maavndmekk laeykcdtne avclklvrfp ediddesttf hpeythqlyg ddevafgykg
       61 lqiqlyysag nlstlfkvky tarvtdtfdc vepddvegkv reiipagfcc ntddfislle
      121 keanfkpfgs llhtykvhsv eagedltyqi hkvdvscpgf reyherlqtf lmwfietasf
      181 idvdddrwdf flvfekynkd getlyatvgy mtvynyyvyp dktrprvsqt lilppfqgeg
      241 hgaqlletvh ryyctsakvq ditaedpsen yvklrdfvlv klcltlpsfs seklsqgfse
      301 emvsearekl kinkkharrv yeilrlrntd msdeekaref rlevkkrlyg pyrknqrelt
      361 kmrkclrpee lashisqmdt slqheeleks fqdvlaeyrr vlerlaqa
//
LOCUS       XP_026128471             252 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Dlx1a [Carassius auratus].
ACCESSION   XP_026128471
VERSION     XP_026128471.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272686.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..252
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..252
                     /product="homeobox protein Dlx1a"
                     /calculated_mol_wt=27517
     Region          129..185
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..252
                     /gene="LOC113109121"
                     /coded_by="XM_026272686.1:1269..2027"
                     /db_xref="GeneID:113109121"
ORIGIN      
        1 mtmstipesl nspvsgksvf mefgppsqqm spssmshghy smhclhssgh pqhesayspa
       61 psfprslpyp yvnsvgshss spylstvqty pnnsalaqtr ledpapesek ntvveggevr
      121 fngkgkkirk prtiysslql qalnrrfqqt qylalperae laaslgltqt qvkiwfqnkr
      181 skfkklmkqg ggtidtnala ngrglstgsp svasvwnsta svktstptsy ipsytswypt
      241 ahqdtmqqpq lm
//
LOCUS       XP_026128472             262 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Dlx2a-like [Carassius auratus].
ACCESSION   XP_026128472
VERSION     XP_026128472.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272687.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..262
                     /product="homeobox protein Dlx2a-like"
                     /calculated_mol_wt=28646
     Region          29..106
                     /region_name="DLL_N"
                     /note="Homeobox protein distal-less-like N terminal;
                     pfam12413"
                     /db_xref="CDD:463567"
     Region          127..183
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..262
                     /gene="LOC113109123"
                     /coded_by="XM_026272687.1:160..948"
                     /db_xref="GeneID:113109123"
ORIGIN      
        1 mtgvfdslst dmhanqitss syhslhksqe sptlpvstat dssyynnnqq agqcagspyg
       61 qissyqyqnn smnsvqyntk syelgfsnaf gsystfgscs saapadaeke esepeirmvn
      121 gkpkkvrkpr tiyssfqlaa llrrfqktqy lalperaela aslgltqtqv kiwfqnrrsk
      181 fkklwksgei paeqhvassg spaqasppls aswdfhtgls qsssppsttt asfltnypwy
      241 sstshlqppl hhntpvsagt if
//
LOCUS       XP_026128474            1091 aa            linear   VRT 18-JUN-2025
DEFINITION  integrin alpha-6-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128474
VERSION     XP_026128474.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272689.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1091
                     /product="integrin alpha-6-like isoform X1"
                     /calculated_mol_wt=120749
     Region          40..101
                     /region_name="Int_alpha"
                     /note="Integrin alpha (beta-propellor repeats);
                     smart00191"
                     /db_xref="CDD:214549"
     Region          257..>293
                     /region_name="Int_alpha"
                     /note="Integrin alpha (beta-propellor repeats);
                     smart00191"
                     /db_xref="CDD:214549"
     Region          320..358
                     /region_name="FG-GAP"
                     /note="FG-GAP repeat; pfam01839"
                     /db_xref="CDD:460357"
     Region          378..431
                     /region_name="Int_alpha"
                     /note="Integrin alpha (beta-propellor repeats);
                     smart00191"
                     /db_xref="CDD:214549"
     Region          440..>463
                     /region_name="Int_alpha"
                     /note="Integrin alpha (beta-propellor repeats);
                     smart00191"
                     /db_xref="CDD:214549"
     Region          476..938
                     /region_name="Integrin_alpha2"
                     /note="Integrin alpha; pfam08441"
                     /db_xref="CDD:462478"
     CDS             1..1091
                     /gene="LOC113109124"
                     /coded_by="XM_026272689.1:113..3388"
                     /db_xref="GeneID:113109124"
ORIGIN      
        1 mglfeegfsl nlciislllw tstsafnlda qnvlrkngqp gslfgfslal hrqlqpydkr
       61 illigapkar alsnqganvt gglyscditt hpddctrvdf dndvdarven kenqwmgvtv
      121 qsqgpggkiv tcahryqrll fpntpqeard itgrcymlsq dlsidsqsde dggnwkfcdg
      181 rtrgherfga cqqglaatft kdyhyvifga pgaynwkgiv rveqknntll emglfddgpy
      241 evgdenrldp nlvpvpansy lgfsldsghs itekgrlviv sgapranhsg avvflrtege
      301 vsttltpehi legpglassf gydvsvvdln gdgwqdvvvg apqffqrdee vggavfvyin
      361 kagrwkdvap trlngtkdsm fglavenigd inldsfqdia vgapytdsgs gsvyiyhgsa
      421 dginttpaqi legkqhnikm fgyslagnmd ldqnsypdla vgslsdtvfi yrsknvisik
      481 kdikvtpkei dlaektcgns vcltveacfs ykakpstynp kltisctlea ewyrrklglp
      541 srvvfleksa mdqdfqstgs lelrgqnkka cyktklrlqe girdklraip ievsvaiqsa
      601 trgkrhsslp qltpildstv pnktitevnf lkegcgtdni cqsnlqlqyr fcyreskqev
      661 fpplplengv pvislsdqkd ialevtvrnr ngddahearl vghfdeslsy sgfrstdkhv
      721 icaanqngsq adcelgnpfk rdsevtfyii lstgkisldt keveidlqle ttssqqglgk
      781 vkakakvvie lllsvqgaak psqvyfggev rgmsamktee evgslveyef rvinlgrplk
      841 sfgtaslsiq wpkessvgkw llylmkintr dlqsvtcspe teinplrlqs qestssrrkr
      901 eleerkpaeg sktslipdkr khkilscsgd arcveikcpl qsldstalim lksrlwnstf
      961 ledyvsysyl diivkasisl dasaknivlk nsetqvrltv fpetagtpfg gvpwwiilva
     1021 vlagvlmlal lvlllwkcgf fkrskyedsv pkyhavrirk etrlvkdgkd mldplekkqw
     1081 mttwdenesy s
//
LOCUS       XP_026128475            1070 aa            linear   VRT 18-JUN-2025
DEFINITION  integrin alpha-6-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128475
VERSION     XP_026128475.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272690.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1070
                     /product="integrin alpha-6-like isoform X2"
                     /calculated_mol_wt=117932
     Region          40..101
                     /region_name="Int_alpha"
                     /note="Integrin alpha (beta-propellor repeats);
                     smart00191"
                     /db_xref="CDD:214549"
     Region          257..>293
                     /region_name="Int_alpha"
                     /note="Integrin alpha (beta-propellor repeats);
                     smart00191"
                     /db_xref="CDD:214549"
     Region          320..358
                     /region_name="FG-GAP"
                     /note="FG-GAP repeat; pfam01839"
                     /db_xref="CDD:460357"
     Region          378..431
                     /region_name="Int_alpha"
                     /note="Integrin alpha (beta-propellor repeats);
                     smart00191"
                     /db_xref="CDD:214549"
     Region          440..>463
                     /region_name="Int_alpha"
                     /note="Integrin alpha (beta-propellor repeats);
                     smart00191"
                     /db_xref="CDD:214549"
     Region          476..938
                     /region_name="Integrin_alpha2"
                     /note="Integrin alpha; pfam08441"
                     /db_xref="CDD:462478"
     CDS             1..1070
                     /gene="LOC113109124"
                     /coded_by="XM_026272690.1:113..3325"
                     /db_xref="GeneID:113109124"
ORIGIN      
        1 mglfeegfsl nlciislllw tstsafnlda qnvlrkngqp gslfgfslal hrqlqpydkr
       61 illigapkar alsnqganvt gglyscditt hpddctrvdf dndvdarven kenqwmgvtv
      121 qsqgpggkiv tcahryqrll fpntpqeard itgrcymlsq dlsidsqsde dggnwkfcdg
      181 rtrgherfga cqqglaatft kdyhyvifga pgaynwkgiv rveqknntll emglfddgpy
      241 evgdenrldp nlvpvpansy lgfsldsghs itekgrlviv sgapranhsg avvflrtege
      301 vsttltpehi legpglassf gydvsvvdln gdgwqdvvvg apqffqrdee vggavfvyin
      361 kagrwkdvap trlngtkdsm fglavenigd inldsfqdia vgapytdsgs gsvyiyhgsa
      421 dginttpaqi legkqhnikm fgyslagnmd ldqnsypdla vgslsdtvfi yrsknvisik
      481 kdikvtpkei dlaektcgns vcltveacfs ykakpstynp kltisctlea ewyrrklglp
      541 srvvfleksa mdqdfqstgs lelrgqnkka cyktklrlqe girdklraip ievsvaiqsa
      601 trgkrhsslp qltpildstv pnktitevnf lkegcgtdni cqsnlqlqyr fcyreskqev
      661 fpplplengv pvislsdqkd ialevtvrnr ngddahearl vghfdeslsy sgfrstdkhv
      721 icaanqngsq adcelgnpfk rdsevtfyii lstgkisldt keveidlqle ttssqqglgk
      781 vkakakvvie lllsvqgaak psqvyfggev rgmsamktee evgslveyef rvinlgrplk
      841 sfgtaslsiq wpkessvgkw llylmkintr dlqsvtcspe teinplrlqs qestssrrkr
      901 eleerkpaeg sktslipdkr khkilscsgd arcveikcpl qsldstalim lksrlwnstf
      961 ledyvsysyl diivkasisl dasaknivlk nsetqvrltv fpetagtpfg gvpwwiilva
     1021 vlagvlmlal lvlllwkcgf fkraqkdeyd aafhkaeiha qpsdkqstea
//
LOCUS       XP_026128476             718 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase tousled-like 1-B isoform X1
            [Carassius auratus].
ACCESSION   XP_026128476
VERSION     XP_026128476.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272691.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..718
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..718
                     /product="serine/threonine-protein kinase tousled-like 1-B
                     isoform X1"
                     /calculated_mol_wt=81401
     Region          413..711
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(426..429,432,434,447,449,485,502..505,550,554..555,
                     557,570..571)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..718
                     /gene="LOC113109126"
                     /coded_by="XM_026272691.1:167..2323"
                     /db_xref="GeneID:113109126"
ORIGIN      
        1 meelhsldpr rqellearfl ggvsgntags tgsasggtkt ltnnecsnhs fgslgsssdk
       61 esegsdgkrg sspafstpek khsessrgrk rkadiqsess qgksvirgpk isdyfdfqag
      121 ngsspvrglp pvirspqnsh shsapgsstr qssssptslc fvdsmistrp mavksvqtdl
      181 tvvklaties nknldlekke griddllran cdlrrqideq qkllekyker lnkcitmskk
      241 lliekstqek qacreksmqd rlrlghftsv rhgasfteqw tdgyafqnlv kqqewiiqqr
      301 eeierqrkll akrkpssass sqspstisep kprktkavng aendpflkps lpqlltlaey
      361 heqeeilklr lgnlkkeeae iqaelerler vrnlhirelk rinnedssqf kdhptlnery
      421 lllhllgrgg fsevykafdl ieqrytavki hqlnknwree kkenyhkhac reyrihkqld
      481 hprivklydy fsldtdtfct vleycegndl dfylkqhklm sekearsivm qivnalryln
      541 eikppiihyd lkpgnillvd gnacgeikit dfglskimdd dsygvdgmdl tsqgagtywy
      601 lppecfvvgk eppkisnkvd vwsvgviffq clygrkpfgh nqsqqdilqe ntilkatevq
      661 fpskpvasne akafirrcla yrkedrfdvh qlgrdsyllp hirrpsssga lapnsssy
//
LOCUS       XP_026128477             705 aa            linear   VRT 18-JUN-2025
DEFINITION  serine/threonine-protein kinase tousled-like 1-B isoform X2
            [Carassius auratus].
ACCESSION   XP_026128477
VERSION     XP_026128477.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272692.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..705
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..705
                     /product="serine/threonine-protein kinase tousled-like 1-B
                     isoform X2"
                     /calculated_mol_wt=80167
     Region          400..698
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(413..416,419,421,434,436,472,489..492,537,541..542,
                     544,557..558)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..705
                     /gene="LOC113109126"
                     /coded_by="XM_026272692.1:191..2308"
                     /db_xref="GeneID:113109126"
ORIGIN      
        1 meelhsldpr rqellearfl ggvsgntags tgsasggtkt ltnnecsnhs fgslgsssdk
       61 esetpekkhs essrgrkrka diqsessqgk svirgpkisd yfdfqagngs spvrglppvi
      121 rspqnshshs apgsstrqss ssptslcfvd smistrpmav ksvqtdltvv klatiesnkn
      181 ldlekkegri ddllrancdl rrqideqqkl lekykerlnk citmskklli ekstqekqac
      241 reksmqdrlr lghftsvrhg asfteqwtdg yafqnlvkqq ewiiqqreei erqrkllakr
      301 kpssasssqs pstisepkpr ktkavngaen dpflkpslpq lltlaeyheq eeilklrlgn
      361 lkkeeaeiqa elerlervrn lhirelkrin nedssqfkdh ptlnerylll hllgrggfse
      421 vykafdlieq rytavkihql nknwreekke nyhkhacrey rihkqldhpr ivklydyfsl
      481 dtdtfctvle ycegndldfy lkqhklmsek earsivmqiv nalrylneik ppiihydlkp
      541 gnillvdgna cgeikitdfg lskimdddsy gvdgmdltsq gagtywylpp ecfvvgkepp
      601 kisnkvdvws vgviffqcly grkpfghnqs qqdilqenti lkatevqfps kpvasneaka
      661 firrclayrk edrfdvhqlg rdsyllphir rpsssgalap nsssy
//
LOCUS       XP_026128478             591 aa            linear   VRT 18-JUN-2025
DEFINITION  glutamate decarboxylase 1-like [Carassius auratus].
ACCESSION   XP_026128478
VERSION     XP_026128478.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272693.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..591
                     /product="glutamate decarboxylase 1-like"
                     /calculated_mol_wt=66600
     Region          141..515
                     /region_name="Pyridoxal_deC"
                     /note="Pyridoxal-dependent decarboxylase conserved domain;
                     pfam00282"
                     /db_xref="CDD:395219"
     Site            order(249..250,253,341,370,373,399,402)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99743"
     Site            402
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99743"
     CDS             1..591
                     /gene="LOC113109128"
                     /coded_by="XM_026272693.1:1..1776"
                     /db_xref="GeneID:113109128"
ORIGIN      
        1 maasssssss sggdpdpnst nlrppssnyd wsgvahgctr klgmkicgfl qknnnvddks
       61 rivgfineqq pksiltrdna rdarfrraet dfsnlyardl lpakngeeyt mqfllevvdi
      121 ltnyvrktfd rstkvldfhh phqllegmeg fnldlcdepe sleqilvdcr dtlkygirtg
      181 hprffnqlss gldiiglage wltstantnm ftyeiapvfv lmeqltlkkm reiigwpnge
      241 gdgifspgga isnmyslmva rykhypevki kgmaaaprlv lftsehshys ikkasavlgf
      301 gtenlillkt dergrvipad leakvidakq kgfvpvfvna tagstvygaf dpineiadic
      361 ekyniwlhvd gawgggllms rkhrhklngv eransvtwnp hkmmgvplqc sailvrekgl
      421 lqgcnsmcag ylfqpdkqyd vtydtgdkai qcgrhvdifk fwlmwkskgt igfekhidrc
      481 lelseylyhk iknregyemv fqgepqhtnv cfwyippslr llpdgeekrq rlhkvapkik
      541 ammmecgttm vgyqpqgnkv nffrmvvsnp avtrsdidfl ideierlgqd l
//
LOCUS       XP_026128479             365 aa            linear   VRT 18-JUN-2025
DEFINITION  transcription factor Sp5-like [Carassius auratus].
ACCESSION   XP_026128479
VERSION     XP_026128479.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272694.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..365
                     /product="transcription factor Sp5-like"
                     /calculated_mol_wt=40691
     Region          23..>44
                     /region_name="SP1-4_N"
                     /note="N-terminal domain of transcription factor
                     Specificity Proteins (SP) 1-4; cl41773"
                     /db_xref="CDD:425404"
     Region          103..261
                     /region_name="SP5_N"
                     /note="N-terminal domain of transcription factor
                     Specificity Protein (SP) 5; cd22541"
                     /db_xref="CDD:412096"
     Region          265..284
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(269,271,273,275..276,279..280,283,299,301,305..306,
                     309..310,313,327,329,331,333..334,337..338,341)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          290..314
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          292..314
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          306..329
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          322..342
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..365
                     /gene="LOC113109129"
                     /coded_by="XM_026272694.1:625..1722"
                     /db_xref="GeneID:113109129"
ORIGIN      
        1 maavavlrnd tlqaflqdrt pnsspenskh splallaatc nrighhhgst ptdfiqvpyd
       61 ttlgspsrif hpwsneanpq pslsnnssfg lsskshlqgs ytthhelplt ppadptypyd
      121 fspvkmlpcs mqslqsscpp tyvpavtyaa pppiphgfvp ghsglvhqqq rqlspnpgee
      181 ipwwslqqgn hvshpaslgr fpiqrglvlg htdfaqyqtq iaallhtksp latarrcrrc
      241 rcpncqssss sdepgkkkqh ichipgcgkv ygktshlkah lrwhsgerpf vcnwlfcgks
      301 ftrsdelqrh lrthtgekrf vcpdcckrfm rsdhlakhvk thqnkksksh ektsdyvkre
      361 dlrpv
//
LOCUS       XP_026128481            1089 aa            linear   VRT 18-JUN-2025
DEFINITION  mitogen-activated protein kinase kinase kinase kinase 4-like
            [Carassius auratus].
ACCESSION   XP_026128481
VERSION     XP_026128481.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272696.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1089
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1089
                     /product="mitogen-activated protein kinase kinase kinase
                     kinase 4-like"
                     /calculated_mol_wt=124190
     Region          8..289
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(31..34,37,39,52,54,83,105..108,153,157..158,160,
                     170..171)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     Region          771..1069
                     /region_name="CNH"
                     /note="Domain found in NIK1-like kinases, mouse citron and
                     yeast ROM1, ROM2; smart00036"
                     /db_xref="CDD:214481"
     CDS             1..1089
                     /gene="LOC113109130"
                     /coded_by="XM_026272696.1:220..3489"
                     /db_xref="GeneID:113109130"
ORIGIN      
        1 mandspaksl vdidlaslrd pagifelvev vgngtygqvy kgrhvktgql aaikvmdvte
       61 deeeeiklei nmlkkyshhr niatyygafi kksppghddq lwlvmefcga gsitdlvknt
      121 kgntlkedwi ayisreilrg lahlhahhvi hrdikgqnvl ltenaevklv dfgvsaqldr
      181 tvgrrntfig tpywmapevi acdenpdaty dyrsdlwscg itaiemaega pplcdmhpmr
      241 alfliprnpp prlkskkwsk kffsfiegcl vknytqrppt dqllkhpfir dqpnerqvri
      301 qlkdhldrcr kkrgerdete yeysgseeee eeaqeqegep ssivnvpges tlrrdfirlq
      361 qenkerseal rrqqllqeqq lreqeeykrq llaerqkrie qqkeqrrrle eqqrreremr
      421 rqqereqrrr eqeekrrlee lerrrkeeee rrraeeekrr adreqeyirr qleeeqrhle
      481 ilqqqllheq amllvderhr rsvqgspqta avlqkqppav plratepfsn gssssdpqdl
      541 talakelrav edvrpqhkat dyssssedsg ttddeddeev dqeagedsts gpedsrasss
      601 rlsngetvaa ktmvvqdsea sstpckdstl vmrqfqragp vlvlgsgwsp savetgprsc
      661 irglpdllqq sssapcspal splspsdrvp slaetptvpk hkssssftpf idprllqvsp
      721 stgsalnnag ysnearlqea lrqdasrkgs vvnvnpvntr pqndtpeirk ykkrfnseil
      781 caalwgvnll vgtesglmll drsgqgkvyp lisrrrfqqm dvleglnvlv tisgkknklr
      841 vyylswlrnk ilhndpevek kqgwttvgdl egcvhynvvk yerikflvla lknsvevyaw
      901 apkpyhkfma fksfgdlvhk pllvdltvee gqrlkviygs csgfhavdvd sgavydiylp
      961 thiqssiqsh aiiilpntdg iellvcyede gvyvntygri tkdvvlqwge mptsvayirs
     1021 nqimgwgeka ieirsvetgh ldgvfmhkra qrlkflcern dkvffasvrs ggssqvyfmt
     1081 lgrtsllsw
//
LOCUS       XP_026128482             464 aa            linear   VRT 18-JUN-2025
DEFINITION  protein FAM126B-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128482
VERSION     XP_026128482.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272697.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..464
                     /product="protein FAM126B-like isoform X1"
                     /calculated_mol_wt=51840
     Region          21..361
                     /region_name="Hyccin"
                     /note="pfam09790"
                     /db_xref="CDD:462903"
     CDS             1..464
                     /gene="LOC113109131"
                     /coded_by="XM_026272697.1:154..1548"
                     /db_xref="GeneID:113109131"
ORIGIN      
        1 matdrgvved wlsefkalse tqlcgyagvl dqkhtlvpal ysiiqdpdse vrserrsein
       61 ssesahlclc sqllepvchq lfelyrssed rlrrftlqfl pellwvylrr drhssgciea
      121 lllgiynlei vdkdgngkll sflipslskp siyhechcvc vcvcvcvcvq psslgsmalt
      181 egalcqhdli rviysglhpq reaftaqnrf evlcflmlcy nslvvymprs shravcrmss
      241 rlcvsgfprq qlkawtsscv rvllepqfmv qmlaavyhai yngewdagre alddilyraq
      301 lelyseplll gnamksslpg sapdgsqgrk vlqvevtpsi rrvsrctita asirrlrwkr
      361 evdaeqlsre edssglndad egfssgasss sqpsgvrgrk srpsarrtss tsldcrpgqr
      421 sgaearrysi lslqeqhlpe etellspgkq srspsfsmqi isqv
//
LOCUS       XP_026128483             463 aa            linear   VRT 18-JUN-2025
DEFINITION  protein FAM126B-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128483
VERSION     XP_026128483.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272698.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..463
                     /product="protein FAM126B-like isoform X2"
                     /calculated_mol_wt=51741
     Region          21..361
                     /region_name="Hyccin"
                     /note="pfam09790"
                     /db_xref="CDD:462903"
     CDS             1..463
                     /gene="LOC113109131"
                     /coded_by="XM_026272698.1:154..1545"
                     /db_xref="GeneID:113109131"
ORIGIN      
        1 matdrgvved wlsefkalse tqlcgyagvl dqkhtlvpal ysiiqdpdse vrserrsein
       61 ssesahlclc sqllepvchq lfelyrssed rlrrftlqfl pellwvylrr drhssgciea
      121 lllgiynlei vdkdgngkll sflipslskp siyhechcvc vcvcvcvcvq psslgsmalt
      181 egalcqhdli rviysglhpq reaftaqnrf evlcflmlcy nslvvymprs shravcrmss
      241 rlcvsgfprq qlkawtsscv rvllepqfmv qmlaavyhai yngewdagre alddilyraq
      301 lelyseplll gnamksslpg sapdgsqgrk vlqvevtpsi rrvsrctita asirrlrwkr
      361 edaeqlsree dssglndade gfssgassss qpsgvrgrks rpsarrtsst sldcrpgqrs
      421 gaearrysil slqeqhlpee tellspgkqs rspsfsmqii sqv
//
LOCUS       XP_026128484             449 aa            linear   VRT 18-JUN-2025
DEFINITION  protein FAM126B-like isoform X3 [Carassius auratus].
ACCESSION   XP_026128484
VERSION     XP_026128484.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272699.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..449
                     /product="protein FAM126B-like isoform X3"
                     /calculated_mol_wt=50258
     Region          21..346
                     /region_name="Hyccin"
                     /note="pfam09790"
                     /db_xref="CDD:462903"
     CDS             1..449
                     /gene="LOC113109131"
                     /coded_by="XM_026272699.1:154..1503"
                     /db_xref="GeneID:113109131"
ORIGIN      
        1 matdrgvved wlsefkalse tqlcgyagvl dqkhtlvpal ysiiqdpdse vrserrsein
       61 ssesahlclc sqllepvchq lfelyrssed rlrrftlqfl pellwvylrr drhssgciea
      121 lllgiynlei vdkdgngkll sflipslskp siyhepsslg smaltegalc qhdlirviys
      181 glhpqreaft aqnrfevlcf lmlcynslvv ymprsshrav crmssrlcvs gfprqqlkaw
      241 tsscvrvlle pqfmvqmlaa vyhaiyngew dagrealddi lyraqlelys eplllgnamk
      301 sslpgsapdg sqgrkvlqve vtpsirrvsr ctitaasirr lrwkrevdae qlsreedssg
      361 lndadegfss gassssqpsg vrgrksrpsa rrtsstsldc rpgqrsgaea rrysilslqe
      421 qhlpeetell spgkqsrsps fsmqiisqv
//
LOCUS       XP_026128485             442 aa            linear   VRT 18-JUN-2025
DEFINITION  protein FAM126B-like isoform X4 [Carassius auratus].
ACCESSION   XP_026128485
VERSION     XP_026128485.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272700.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..442
                     /product="protein FAM126B-like isoform X4"
                     /calculated_mol_wt=49367
     Region          21..339
                     /region_name="Hyccin"
                     /note="pfam09790"
                     /db_xref="CDD:462903"
     CDS             1..442
                     /gene="LOC113109131"
                     /coded_by="XM_026272700.1:154..1482"
                     /db_xref="GeneID:113109131"
ORIGIN      
        1 matdrgvved wlsefkalse tqlcgyagvl dqkhtlvpal ysiiqdpdse llepvchqlf
       61 elyrssedrl rrftlqflpe llwvylrrdr hssgcieall lgiynleivd kdgngkllsf
      121 lipslskpsi yhechcvcvc vcvcvcvqps slgsmalteg alcqhdlirv iysglhpqre
      181 aftaqnrfev lcflmlcyns lvvymprssh ravcrmssrl cvsgfprqql kawtsscvrv
      241 llepqfmvqm laavyhaiyn gewdagreal ddilyraqle lyseplllgn amksslpgsa
      301 pdgsqgrkvl qvevtpsirr vsrctitaas irrlrwkrev daeqlsreed ssglndadeg
      361 fssgassssq psgvrgrksr psarrtssts ldcrpgqrsg aearrysils lqeqhlpeet
      421 ellspgkqsr spsfsmqiis qv
//
LOCUS       XP_026128486             427 aa            linear   VRT 18-JUN-2025
DEFINITION  protein FAM126B-like isoform X5 [Carassius auratus].
ACCESSION   XP_026128486
VERSION     XP_026128486.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272701.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..427
                     /product="protein FAM126B-like isoform X5"
                     /calculated_mol_wt=47785
     Region          21..324
                     /region_name="Hyccin"
                     /note="pfam09790"
                     /db_xref="CDD:462903"
     CDS             1..427
                     /gene="LOC113109131"
                     /coded_by="XM_026272701.1:154..1437"
                     /db_xref="GeneID:113109131"
ORIGIN      
        1 matdrgvved wlsefkalse tqlcgyagvl dqkhtlvpal ysiiqdpdse llepvchqlf
       61 elyrssedrl rrftlqflpe llwvylrrdr hssgcieall lgiynleivd kdgngkllsf
      121 lipslskpsi yhepsslgsm altegalcqh dlirviysgl hpqreaftaq nrfevlcflm
      181 lcynslvvym prsshravcr mssrlcvsgf prqqlkawts scvrvllepq fmvqmlaavy
      241 haiyngewda grealddily raqlelysep lllgnamkss lpgsapdgsq grkvlqvevt
      301 psirrvsrct itaasirrlr wkrevdaeql sreedssgln dadegfssga ssssqpsgvr
      361 grksrpsarr tsstsldcrp gqrsgaearr ysilslqeqh lpeetellsp gkqsrspsfs
      421 mqiisqv
//
LOCUS       XP_026128487             426 aa            linear   VRT 18-JUN-2025
DEFINITION  protein FAM126B-like isoform X6 [Carassius auratus].
ACCESSION   XP_026128487
VERSION     XP_026128487.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272702.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..426
                     /product="protein FAM126B-like isoform X6"
                     /calculated_mol_wt=47685
     Region          21..324
                     /region_name="Hyccin"
                     /note="pfam09790"
                     /db_xref="CDD:462903"
     CDS             1..426
                     /gene="LOC113109131"
                     /coded_by="XM_026272702.1:154..1434"
                     /db_xref="GeneID:113109131"
ORIGIN      
        1 matdrgvved wlsefkalse tqlcgyagvl dqkhtlvpal ysiiqdpdse llepvchqlf
       61 elyrssedrl rrftlqflpe llwvylrrdr hssgcieall lgiynleivd kdgngkllsf
      121 lipslskpsi yhepsslgsm altegalcqh dlirviysgl hpqreaftaq nrfevlcflm
      181 lcynslvvym prsshravcr mssrlcvsgf prqqlkawts scvrvllepq fmvqmlaavy
      241 haiyngewda grealddily raqlelysep lllgnamkss lpgsapdgsq grkvlqvevt
      301 psirrvsrct itaasirrlr wkredaeqls reedssglnd adegfssgas sssqpsgvrg
      361 rksrpsarrt sstsldcrpg qrsgaearry silslqeqhl peetellspg kqsrspsfsm
      421 qiisqv
//
LOCUS       XP_026128488             378 aa            linear   VRT 18-JUN-2025
DEFINITION  interferon alpha/beta receptor 1a-like [Carassius auratus].
ACCESSION   XP_026128488
VERSION     XP_026128488.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272703.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..378
                     /product="interferon alpha/beta receptor 1a-like"
                     /calculated_mol_wt=43381
     Region          6..116
                     /region_name="Tissue_fac"
                     /note="Tissue factor; pfam01108"
                     /db_xref="CDD:460067"
     Region          127..230
                     /region_name="Interfer-bind"
                     /note="Interferon-alpha/beta receptor, fibronectin type
                     III; pfam09294"
                     /db_xref="CDD:462746"
     CDS             1..378
                     /gene="LOC113109134"
                     /coded_by="XM_026272703.1:105..1241"
                     /db_xref="GeneID:113109134"
ORIGIN      
        1 mkslrcfcvc sllllkvstg fgdlrrpenv smdslntryv lrwdwpheta inqtvtftaq
       61 yileyqsrka nyeqywtsvc vnvrehycdf sgaelhyngl fllrvqants qqssswvqir
      121 fcpdeqaalg ppssvklspv kgdleiiitd plsstnqsmk tllndnmgyl iqywrrseep
      181 qkakvletkn nlvmlteldr qtwycvrvqs rdvfnnkssv fsdtqcthte gqmpywetfl
      241 yvliglllff lllyfcfykm ftllkntfyp aiqlpdhiqe llfsesekpq llspeypvsv
      301 cvplvlvrte ldavavnees nageqdssth sqhssgdsgi ysteedsshr stthtdlqms
      361 sqkhreklhd gtllelca
//
LOCUS       XP_026128490             378 aa            linear   VRT 18-JUN-2025
DEFINITION  interferon alpha/beta receptor 1a-like [Carassius auratus].
ACCESSION   XP_026128490
VERSION     XP_026128490.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272705.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..378
                     /product="interferon alpha/beta receptor 1a-like"
                     /calculated_mol_wt=43366
     Region          6..116
                     /region_name="Tissue_fac"
                     /note="Tissue factor; pfam01108"
                     /db_xref="CDD:460067"
     Region          127..230
                     /region_name="Interfer-bind"
                     /note="Interferon-alpha/beta receptor, fibronectin type
                     III; pfam09294"
                     /db_xref="CDD:462746"
     CDS             1..378
                     /gene="LOC113109136"
                     /coded_by="XM_026272705.1:115..1251"
                     /db_xref="GeneID:113109136"
ORIGIN      
        1 mkslrcfcvc sllllkvstg fgdlrrpenv smdslntryv lrwdwpheta inqtvtftaq
       61 yileyqsrka snekkwrlvc vnvlehhcdf tgailhykis fllrvrantk qqssswvqis
      121 fcpedhaalg ppssvklspv kgdleiiitd plsstnqsmk tlledklsyl iqywrrseep
      181 qkakvletkn nlvmltelyr qtwycvrvqs rdvlhnkssv fsdtqcthte gqmpywetfl
      241 yvliglllff lllyfcfykm ftllkntfyp aiqlpdhiqe llfsesekpq llspecpvsv
      301 cvplvlvrte ldavavnees nageqdssth srhssgdsgv ysteedsshr stthtdlqms
      361 sqkhreklhd gtllelca
//
LOCUS       XP_026128491            3017 aa            linear   VRT 18-JUN-2025
DEFINITION  RANBP2-like and GRIP domain-containing protein 5/6 isoform X1
            [Carassius auratus].
ACCESSION   XP_026128491
VERSION     XP_026128491.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272706.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..3017
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..3017
                     /product="RANBP2-like and GRIP domain-containing protein
                     5/6 isoform X1"
                     /calculated_mol_wt=333577
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1178..1294
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1331..1360
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1335..1354
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1387..1414
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1439..1468
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1500..1524
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1544..1570
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1548..1567
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1591..1620
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1595..1614
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1847..1963
                     /region_name="RanBD2_RanBP2-like"
                     /note="Ran-binding protein 2, Ran binding domain repeat 2;
                     cd13177"
                     /db_xref="CDD:269998"
     Site            order(1861,1863..1865,1870..1875,1892,1894,1896..1897,
                     1899,1901..1903,1906,1908,1912,1916,1926,1928,1941,1945)
                     /site_type="other"
                     /note="putative RAN binding site [polypeptide binding]"
                     /db_xref="CDD:269998"
     Region          2137..2253
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2423..2484
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2494..2549
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2717..2833
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2856..3014
                     /region_name="cyclophilin_ABH_like"
                     /note="Cyclophilin A, B and H-like cyclophilin-type
                     peptidylprolyl cis- trans isomerase (PPIase) domain. This
                     family represents the archetypal cystolic cyclophilin
                     similar to human cyclophilins A, B and H. PPIase is an
                     enzyme which accelerates protein folding...; cd01926"
                     /db_xref="CDD:238907"
     Site            order(2906..2907,2912,2963,2965,2973)
                     /site_type="active"
                     /db_xref="CDD:238907"
     CDS             1..3017
                     /gene="ranbp2"
                     /coded_by="XM_026272706.1:128..9181"
                     /db_xref="GeneID:113109137"
ORIGIN      
        1 mrrskadver yissvqnasp sqktktlkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrkdelaev ftemrahlyl yagtlllkra
      301 qdgpqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqiqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvvqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkyltqi
      721 yqasaedlek lpvsmeevmd llnevnqqlv gevdedqley pvtsspgqpt eghvkfstps
      781 ssksvtspsk rsvfspktpp hwvedqksll qmlcqqveal knevhdlrhn spdatassyr
      841 myrdnyaaeg lqetfpaaqt fhgvpltvat tgpsvyynqs paynsqyllr taanvtptkg
      901 pvygmnrlpp qqhmyayqqs thtpplqstp acmypqeqvf gppirfespa tsllspysee
      961 yyghnvpqpt vnptlpepgy ftkpcpvtst qstrsteska vdpkisfgpq ftgepakvpn
     1021 fggvaagptt tsstafkfns nfksndgdft fssaqvknse sllglltsdi ppkaevssep
     1081 khqtqdqlps qkevftfgsk saagfsftdg apnkmsifgn tdqrfsftsg tkttlgnsea
     1141 reeksgesdn dgthveeded gphfepivpl pdkvdvktge eeeeemfckr aklfrfdset
     1201 kewkergigs ikilkhkssg kvrllmrreq vlkicanhyi tadmvlkpna gsdkswvwya
     1261 mdyadempkt eqlairfkta deatlfkvkf eeaqkflses pqgqqtekks etpkpqvssk
     1321 evdlktlfsk kagewdcdvc cvrnaptsav cvacnsaaps taqvkpveep kgsgpvappa
     1381 klfsfglsgd saksatstdi cskgftfgsa sfkfgsndav etsagfgaqa ekntsqtdap
     1441 qrekvsaapa vpfgtgfgav dtstgfgaqa ekktsqadap qrekvstapa vpfgtgfgav
     1501 dtstgfgaqa ekktsqadap qrekvsaapa vpfgtgfgaq fakkdgqwdc dsclvrndas
     1561 atecvsckap cstvktnaas kgglaamfgk kagqwdcdtc lvrnegsssh cvscqtanpn
     1621 mknktsaaps sssftfsfgs sssqpaatgf kanfnpgpaf qfgtskekts leafkfesst
     1681 teaekssgss tfafsmptpv ggfkfgiaes eakpsdgqsq ngsasgllkn iaahhkeken
     1741 ekeaapssse qsvdsdsqdn nplftgkpnt fsfadlaktq gsfqfgqedp tfkgfagage
     1801 plftglypgp kadtsvdqdd emykteendn iqfepvvqmp ekvdlvtgee dekvlysqrv
     1861 klfrfdtetn qwkergvgnl kllknnqngr lrvlmrreqv lkvcanhwit ttmnlkplsg
     1921 sdrawmwlas dfsdgdakle qlaakfktpe laeefklkfe esqrllldip lqtphkltnt
     1981 grtahliqka eemksglkdl ksfltsqnkd desadtshst savvvkldse gtahtlewdn
     2041 ydlheevhkd ygsssvrdtp lqpdpvaknl frfgesssgf sfcfqpilsp skspsklnqs
     2101 qasigtddeq evsqeeerdg qyfepvvplp dlvevstgee neqvlfshra klyrydkdln
     2161 qwkergigdl kilqhyetkr vrlvmrrdqv lklcanhwiv snmklepmkg aekawiwsaf
     2221 dfaegqgkve qlavrfklqe tanafseife eaktaqekdt lltpfsaklp astqemlcgk
     2281 aavavleett kertgisees spkldqtpqs tknvvsppkf vfgsdsvqki fgspspskdk
     2341 slvvissled eeagasrlkt sgaavasqss vqtpfsiptr sldfrlfknn pmafwtctsa
     2401 nqsearvysp sekksaqdvs dddieivfec kptraqaela arlmlpptff cyknspgyis
     2461 dedsddedfe savrnlkgkl yvdgadgasd hdsevtlvwe krptadeeqr arrlllpptf
     2521 lcgvssdsea eaeklddfst evqkvqqaqv kpvrwesgpq eisvsssapq dtqvkpvrwe
     2581 sgpqeisgss sapqdtqvkp epsdggaeer qtdgsrpidl stkrssesds statalsfgf
     2641 tsaagfsfae laktsgefaf gkkdagfsws gagasvfgsa aaqtkeaeee dsddetphsd
     2701 eihfepivsl pevevrsgee deeilfkera klyrwdreln qwkergvgdi kilfhpekks
     2761 yrllmrreqv lkvcanhtis pgielkpmnt sanalvwtat dysegdgkve qlaakfktpe
     2821 laesfrraft dtqtrmsqtd aaqtsaaeal srdsnpvvff disideehag rvvmelfahi
     2881 vprtaenfra lctgekgfgy rrsvfhriip dfmcqggdft shdgtggrsi yggkfedesf
     2941 evrhtgpgll smanrgrdtn nsqffitlkk aehldfkhva fgfvkdgmdv vrrmgelgtk
     3001 dgkpthtisi secgqil
//
LOCUS       XP_026128492            2993 aa            linear   VRT 18-JUN-2025
DEFINITION  RANBP2-like and GRIP domain-containing protein 5/6 isoform X2
            [Carassius auratus].
ACCESSION   XP_026128492
VERSION     XP_026128492.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272707.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2993
                     /product="RANBP2-like and GRIP domain-containing protein
                     5/6 isoform X2"
                     /calculated_mol_wt=331024
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1178..1294
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1331..1360
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1335..1354
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1387..1414
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1439..1468
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1500..1524
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1544..1570
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1548..1567
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1591..1620
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1595..1614
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1847..1963
                     /region_name="RanBD2_RanBP2-like"
                     /note="Ran-binding protein 2, Ran binding domain repeat 2;
                     cd13177"
                     /db_xref="CDD:269998"
     Site            order(1861,1863..1865,1870..1875,1892,1894,1896..1897,
                     1899,1901..1903,1906,1908,1912,1916,1926,1928,1941,1945)
                     /site_type="other"
                     /note="putative RAN binding site [polypeptide binding]"
                     /db_xref="CDD:269998"
     Region          2137..2253
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2423..2484
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2494..2549
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2693..2809
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2832..2990
                     /region_name="cyclophilin_ABH_like"
                     /note="Cyclophilin A, B and H-like cyclophilin-type
                     peptidylprolyl cis- trans isomerase (PPIase) domain. This
                     family represents the archetypal cystolic cyclophilin
                     similar to human cyclophilins A, B and H. PPIase is an
                     enzyme which accelerates protein folding...; cd01926"
                     /db_xref="CDD:238907"
     Site            order(2882..2883,2888,2939,2941,2949)
                     /site_type="active"
                     /db_xref="CDD:238907"
     CDS             1..2993
                     /gene="ranbp2"
                     /coded_by="XM_026272707.1:128..9109"
                     /db_xref="GeneID:113109137"
ORIGIN      
        1 mrrskadver yissvqnasp sqktktlkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrkdelaev ftemrahlyl yagtlllkra
      301 qdgpqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqiqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvvqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkyltqi
      721 yqasaedlek lpvsmeevmd llnevnqqlv gevdedqley pvtsspgqpt eghvkfstps
      781 ssksvtspsk rsvfspktpp hwvedqksll qmlcqqveal knevhdlrhn spdatassyr
      841 myrdnyaaeg lqetfpaaqt fhgvpltvat tgpsvyynqs paynsqyllr taanvtptkg
      901 pvygmnrlpp qqhmyayqqs thtpplqstp acmypqeqvf gppirfespa tsllspysee
      961 yyghnvpqpt vnptlpepgy ftkpcpvtst qstrsteska vdpkisfgpq ftgepakvpn
     1021 fggvaagptt tsstafkfns nfksndgdft fssaqvknse sllglltsdi ppkaevssep
     1081 khqtqdqlps qkevftfgsk saagfsftdg apnkmsifgn tdqrfsftsg tkttlgnsea
     1141 reeksgesdn dgthveeded gphfepivpl pdkvdvktge eeeeemfckr aklfrfdset
     1201 kewkergigs ikilkhkssg kvrllmrreq vlkicanhyi tadmvlkpna gsdkswvwya
     1261 mdyadempkt eqlairfkta deatlfkvkf eeaqkflses pqgqqtekks etpkpqvssk
     1321 evdlktlfsk kagewdcdvc cvrnaptsav cvacnsaaps taqvkpveep kgsgpvappa
     1381 klfsfglsgd saksatstdi cskgftfgsa sfkfgsndav etsagfgaqa ekntsqtdap
     1441 qrekvsaapa vpfgtgfgav dtstgfgaqa ekktsqadap qrekvstapa vpfgtgfgav
     1501 dtstgfgaqa ekktsqadap qrekvsaapa vpfgtgfgaq fakkdgqwdc dsclvrndas
     1561 atecvsckap cstvktnaas kgglaamfgk kagqwdcdtc lvrnegsssh cvscqtanpn
     1621 mknktsaaps sssftfsfgs sssqpaatgf kanfnpgpaf qfgtskekts leafkfesst
     1681 teaekssgss tfafsmptpv ggfkfgiaes eakpsdgqsq ngsasgllkn iaahhkeken
     1741 ekeaapssse qsvdsdsqdn nplftgkpnt fsfadlaktq gsfqfgqedp tfkgfagage
     1801 plftglypgp kadtsvdqdd emykteendn iqfepvvqmp ekvdlvtgee dekvlysqrv
     1861 klfrfdtetn qwkergvgnl kllknnqngr lrvlmrreqv lkvcanhwit ttmnlkplsg
     1921 sdrawmwlas dfsdgdakle qlaakfktpe laeefklkfe esqrllldip lqtphkltnt
     1981 grtahliqka eemksglkdl ksfltsqnkd desadtshst savvvkldse gtahtlewdn
     2041 ydlheevhkd ygsssvrdtp lqpdpvaknl frfgesssgf sfcfqpilsp skspsklnqs
     2101 qasigtddeq evsqeeerdg qyfepvvplp dlvevstgee neqvlfshra klyrydkdln
     2161 qwkergigdl kilqhyetkr vrlvmrrdqv lklcanhwiv snmklepmkg aekawiwsaf
     2221 dfaegqgkve qlavrfklqe tanafseife eaktaqekdt lltpfsaklp astqemlcgk
     2281 aavavleett kertgisees spkldqtpqs tknvvsppkf vfgsdsvqki fgspspskdk
     2341 slvvissled eeagasrlkt sgaavasqss vqtpfsiptr sldfrlfknn pmafwtctsa
     2401 nqsearvysp sekksaqdvs dddieivfec kptraqaela arlmlpptff cyknspgyis
     2461 dedsddedfe savrnlkgkl yvdgadgasd hdsevtlvwe krptadeeqr arrlllpptf
     2521 lcgvssdsea eaeklddfst evqkvqqaqv kpvrwesgpq eisvsssapq dtqvkpepsd
     2581 ggaeerqtdg srpidlstkr ssesdsstat alsfgftsaa gfsfaelakt sgefafgkkd
     2641 agfswsgaga svfgsaaaqt keaeeedsdd etphsdeihf epivslpeve vrsgeedeei
     2701 lfkeraklyr wdrelnqwke rgvgdikilf hpekksyrll mrreqvlkvc anhtispgie
     2761 lkpmntsana lvwtatdyse gdgkveqlaa kfktpelaes frraftdtqt rmsqtdaaqt
     2821 saaealsrds npvvffdisi deehagrvvm elfahivprt aenfralctg ekgfgyrrsv
     2881 fhriipdfmc qggdftshdg tggrsiyggk fedesfevrh tgpgllsman rgrdtnnsqf
     2941 fitlkkaehl dfkhvafgfv kdgmdvvrrm gelgtkdgkp thtisisecg qil
//
LOCUS       XP_026128493            2993 aa            linear   VRT 18-JUN-2025
DEFINITION  RANBP2-like and GRIP domain-containing protein 5/6 isoform X3
            [Carassius auratus].
ACCESSION   XP_026128493
VERSION     XP_026128493.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272708.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2993
                     /product="RANBP2-like and GRIP domain-containing protein
                     5/6 isoform X3"
                     /calculated_mol_wt=330982
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1178..1294
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1331..1360
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1335..1354
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1387..1414
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1439..1468
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1500..1524
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1544..1570
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1548..1567
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1591..1620
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1595..1614
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1847..1963
                     /region_name="RanBD2_RanBP2-like"
                     /note="Ran-binding protein 2, Ran binding domain repeat 2;
                     cd13177"
                     /db_xref="CDD:269998"
     Site            order(1861,1863..1865,1870..1875,1892,1894,1896..1897,
                     1899,1901..1903,1906,1908,1912,1916,1926,1928,1941,1945)
                     /site_type="other"
                     /note="putative RAN binding site [polypeptide binding]"
                     /db_xref="CDD:269998"
     Region          2137..2253
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2423..2484
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2494..2549
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2693..2809
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2832..2990
                     /region_name="cyclophilin_ABH_like"
                     /note="Cyclophilin A, B and H-like cyclophilin-type
                     peptidylprolyl cis- trans isomerase (PPIase) domain. This
                     family represents the archetypal cystolic cyclophilin
                     similar to human cyclophilins A, B and H. PPIase is an
                     enzyme which accelerates protein folding...; cd01926"
                     /db_xref="CDD:238907"
     Site            order(2882..2883,2888,2939,2941,2949)
                     /site_type="active"
                     /db_xref="CDD:238907"
     CDS             1..2993
                     /gene="ranbp2"
                     /coded_by="XM_026272708.1:128..9109"
                     /db_xref="GeneID:113109137"
ORIGIN      
        1 mrrskadver yissvqnasp sqktktlkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrkdelaev ftemrahlyl yagtlllkra
      301 qdgpqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqiqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvvqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkyltqi
      721 yqasaedlek lpvsmeevmd llnevnqqlv gevdedqley pvtsspgqpt eghvkfstps
      781 ssksvtspsk rsvfspktpp hwvedqksll qmlcqqveal knevhdlrhn spdatassyr
      841 myrdnyaaeg lqetfpaaqt fhgvpltvat tgpsvyynqs paynsqyllr taanvtptkg
      901 pvygmnrlpp qqhmyayqqs thtpplqstp acmypqeqvf gppirfespa tsllspysee
      961 yyghnvpqpt vnptlpepgy ftkpcpvtst qstrsteska vdpkisfgpq ftgepakvpn
     1021 fggvaagptt tsstafkfns nfksndgdft fssaqvknse sllglltsdi ppkaevssep
     1081 khqtqdqlps qkevftfgsk saagfsftdg apnkmsifgn tdqrfsftsg tkttlgnsea
     1141 reeksgesdn dgthveeded gphfepivpl pdkvdvktge eeeeemfckr aklfrfdset
     1201 kewkergigs ikilkhkssg kvrllmrreq vlkicanhyi tadmvlkpna gsdkswvwya
     1261 mdyadempkt eqlairfkta deatlfkvkf eeaqkflses pqgqqtekks etpkpqvssk
     1321 evdlktlfsk kagewdcdvc cvrnaptsav cvacnsaaps taqvkpveep kgsgpvappa
     1381 klfsfglsgd saksatstdi cskgftfgsa sfkfgsndav etsagfgaqa ekntsqtdap
     1441 qrekvsaapa vpfgtgfgav dtstgfgaqa ekktsqadap qrekvstapa vpfgtgfgav
     1501 dtstgfgaqa ekktsqadap qrekvsaapa vpfgtgfgaq fakkdgqwdc dsclvrndas
     1561 atecvsckap cstvktnaas kgglaamfgk kagqwdcdtc lvrnegsssh cvscqtanpn
     1621 mknktsaaps sssftfsfgs sssqpaatgf kanfnpgpaf qfgtskekts leafkfesst
     1681 teaekssgss tfafsmptpv ggfkfgiaes eakpsdgqsq ngsasgllkn iaahhkeken
     1741 ekeaapssse qsvdsdsqdn nplftgkpnt fsfadlaktq gsfqfgqedp tfkgfagage
     1801 plftglypgp kadtsvdqdd emykteendn iqfepvvqmp ekvdlvtgee dekvlysqrv
     1861 klfrfdtetn qwkergvgnl kllknnqngr lrvlmrreqv lkvcanhwit ttmnlkplsg
     1921 sdrawmwlas dfsdgdakle qlaakfktpe laeefklkfe esqrllldip lqtphkltnt
     1981 grtahliqka eemksglkdl ksfltsqnkd desadtshst savvvkldse gtahtlewdn
     2041 ydlheevhkd ygsssvrdtp lqpdpvaknl frfgesssgf sfcfqpilsp skspsklnqs
     2101 qasigtddeq evsqeeerdg qyfepvvplp dlvevstgee neqvlfshra klyrydkdln
     2161 qwkergigdl kilqhyetkr vrlvmrrdqv lklcanhwiv snmklepmkg aekawiwsaf
     2221 dfaegqgkve qlavrfklqe tanafseife eaktaqekdt lltpfsaklp astqemlcgk
     2281 aavavleett kertgisees spkldqtpqs tknvvsppkf vfgsdsvqki fgspspskdk
     2341 slvvissled eeagasrlkt sgaavasqss vqtpfsiptr sldfrlfknn pmafwtctsa
     2401 nqsearvysp sekksaqdvs dddieivfec kptraqaela arlmlpptff cyknspgyis
     2461 dedsddedfe savrnlkgkl yvdgadgasd hdsevtlvwe krptadeeqr arrlllpptf
     2521 lcgvssdsea eaeklddfst evqkvqqaqv kpvrwesgpq eisgsssapq dtqvkpepsd
     2581 ggaeerqtdg srpidlstkr ssesdsstat alsfgftsaa gfsfaelakt sgefafgkkd
     2641 agfswsgaga svfgsaaaqt keaeeedsdd etphsdeihf epivslpeve vrsgeedeei
     2701 lfkeraklyr wdrelnqwke rgvgdikilf hpekksyrll mrreqvlkvc anhtispgie
     2761 lkpmntsana lvwtatdyse gdgkveqlaa kfktpelaes frraftdtqt rmsqtdaaqt
     2821 saaealsrds npvvffdisi deehagrvvm elfahivprt aenfralctg ekgfgyrrsv
     2881 fhriipdfmc qggdftshdg tggrsiyggk fedesfevrh tgpgllsman rgrdtnnsqf
     2941 fitlkkaehl dfkhvafgfv kdgmdvvrrm gelgtkdgkp thtisisecg qil
//
LOCUS       XP_026128494            2991 aa            linear   VRT 18-JUN-2025
DEFINITION  RANBP2-like and GRIP domain-containing protein 5/6 isoform X4
            [Carassius auratus].
ACCESSION   XP_026128494
VERSION     XP_026128494.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272709.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2991
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2991
                     /product="RANBP2-like and GRIP domain-containing protein
                     5/6 isoform X4"
                     /calculated_mol_wt=330573
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1178..1294
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1331..1360
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1335..1354
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1387..1414
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1439..1468
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1500..1524
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1544..1570
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1548..1567
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1591..1620
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1595..1614
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1847..1963
                     /region_name="RanBD2_RanBP2-like"
                     /note="Ran-binding protein 2, Ran binding domain repeat 2;
                     cd13177"
                     /db_xref="CDD:269998"
     Site            order(1861,1863..1865,1870..1875,1892,1894,1896..1897,
                     1899,1901..1903,1906,1908,1912,1916,1926,1928,1941,1945)
                     /site_type="other"
                     /note="putative RAN binding site [polypeptide binding]"
                     /db_xref="CDD:269998"
     Region          2137..2253
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2397..2458
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2468..2523
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2691..2807
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2830..2988
                     /region_name="cyclophilin_ABH_like"
                     /note="Cyclophilin A, B and H-like cyclophilin-type
                     peptidylprolyl cis- trans isomerase (PPIase) domain. This
                     family represents the archetypal cystolic cyclophilin
                     similar to human cyclophilins A, B and H. PPIase is an
                     enzyme which accelerates protein folding...; cd01926"
                     /db_xref="CDD:238907"
     Site            order(2880..2881,2886,2937,2939,2947)
                     /site_type="active"
                     /db_xref="CDD:238907"
     CDS             1..2991
                     /gene="ranbp2"
                     /coded_by="XM_026272709.1:128..9103"
                     /db_xref="GeneID:113109137"
ORIGIN      
        1 mrrskadver yissvqnasp sqktktlkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrkdelaev ftemrahlyl yagtlllkra
      301 qdgpqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqiqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvvqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkyltqi
      721 yqasaedlek lpvsmeevmd llnevnqqlv gevdedqley pvtsspgqpt eghvkfstps
      781 ssksvtspsk rsvfspktpp hwvedqksll qmlcqqveal knevhdlrhn spdatassyr
      841 myrdnyaaeg lqetfpaaqt fhgvpltvat tgpsvyynqs paynsqyllr taanvtptkg
      901 pvygmnrlpp qqhmyayqqs thtpplqstp acmypqeqvf gppirfespa tsllspysee
      961 yyghnvpqpt vnptlpepgy ftkpcpvtst qstrsteska vdpkisfgpq ftgepakvpn
     1021 fggvaagptt tsstafkfns nfksndgdft fssaqvknse sllglltsdi ppkaevssep
     1081 khqtqdqlps qkevftfgsk saagfsftdg apnkmsifgn tdqrfsftsg tkttlgnsea
     1141 reeksgesdn dgthveeded gphfepivpl pdkvdvktge eeeeemfckr aklfrfdset
     1201 kewkergigs ikilkhkssg kvrllmrreq vlkicanhyi tadmvlkpna gsdkswvwya
     1261 mdyadempkt eqlairfkta deatlfkvkf eeaqkflses pqgqqtekks etpkpqvssk
     1321 evdlktlfsk kagewdcdvc cvrnaptsav cvacnsaaps taqvkpveep kgsgpvappa
     1381 klfsfglsgd saksatstdi cskgftfgsa sfkfgsndav etsagfgaqa ekntsqtdap
     1441 qrekvsaapa vpfgtgfgav dtstgfgaqa ekktsqadap qrekvstapa vpfgtgfgav
     1501 dtstgfgaqa ekktsqadap qrekvsaapa vpfgtgfgaq fakkdgqwdc dsclvrndas
     1561 atecvsckap cstvktnaas kgglaamfgk kagqwdcdtc lvrnegsssh cvscqtanpn
     1621 mknktsaaps sssftfsfgs sssqpaatgf kanfnpgpaf qfgtskekts leafkfesst
     1681 teaekssgss tfafsmptpv ggfkfgiaes eakpsdgqsq ngsasgllkn iaahhkeken
     1741 ekeaapssse qsvdsdsqdn nplftgkpnt fsfadlaktq gsfqfgqedp tfkgfagage
     1801 plftglypgp kadtsvdqdd emykteendn iqfepvvqmp ekvdlvtgee dekvlysqrv
     1861 klfrfdtetn qwkergvgnl kllknnqngr lrvlmrreqv lkvcanhwit ttmnlkplsg
     1921 sdrawmwlas dfsdgdakle qlaakfktpe laeefklkfe esqrllldip lqtphkltnt
     1981 grtahliqka eemksglkdl ksfltsqnkd desadtshst savvvkldse gtahtlewdn
     2041 ydlheevhkd ygsssvrdtp lqpdpvaknl frfgesssgf sfcfqpilsp skspsklnqs
     2101 qasigtddeq evsqeeerdg qyfepvvplp dlvevstgee neqvlfshra klyrydkdln
     2161 qwkergigdl kilqhyetkr vrlvmrrdqv lklcanhwiv snmklepmkg aekawiwsaf
     2221 dfaegqgkve qlavrfklqe tanafseife eaktaqekdt lltpfsaklp astqemlcgk
     2281 aavavleett kertgisees spkldqtpqs tknvvsppkf vfgsdsvqki fgspspskdk
     2341 slvvissled eeagasrlkt sgaavasqss vqtpfsiptr iyspsekksa qdvsdddiei
     2401 vfeckptraq aelaarlmlp ptffcyknsp gyisdedsdd edfesavrnl kgklyvdgad
     2461 gasdhdsevt lvwekrptad eeqrarrlll pptflcgvss dseaeaekld dfstevqkvq
     2521 qaqvkpvrwe sgpqeisvss sapqdtqvkp vrwesgpqei sgsssapqdt qvkpepsdgg
     2581 aeerqtdgsr pidlstkrss esdsstatal sfgftsaagf sfaelaktsg efafgkkdag
     2641 fswsgagasv fgsaaaqtke aeeedsddet phsdeihfep ivslpevevr sgeedeeilf
     2701 keraklyrwd relnqwkerg vgdikilfhp ekksyrllmr reqvlkvcan htispgielk
     2761 pmntsanalv wtatdysegd gkveqlaakf ktpelaesfr raftdtqtrm sqtdaaqtsa
     2821 aealsrdsnp vvffdiside ehagrvvmel fahivprtae nfralctgek gfgyrrsvfh
     2881 riipdfmcqg gdftshdgtg grsiyggkfe desfevrhtg pgllsmanrg rdtnnsqffi
     2941 tlkkaehldf khvafgfvkd gmdvvrrmge lgtkdgkpth tisisecgqi l
//
LOCUS       XP_026128495            2989 aa            linear   VRT 18-JUN-2025
DEFINITION  RANBP2-like and GRIP domain-containing protein 5/6 isoform X5
            [Carassius auratus].
ACCESSION   XP_026128495
VERSION     XP_026128495.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272710.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2989
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2989
                     /product="RANBP2-like and GRIP domain-containing protein
                     5/6 isoform X5"
                     /calculated_mol_wt=330637
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1178..1294
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1331..1360
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1335..1354
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1387..1414
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1439..1468
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1500..1524
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1544..1570
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1548..1567
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1591..1620
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1595..1614
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1847..1963
                     /region_name="RanBD2_RanBP2-like"
                     /note="Ran-binding protein 2, Ran binding domain repeat 2;
                     cd13177"
                     /db_xref="CDD:269998"
     Site            order(1861,1863..1865,1870..1875,1892,1894,1896..1897,
                     1899,1901..1903,1906,1908,1912,1916,1926,1928,1941,1945)
                     /site_type="other"
                     /note="putative RAN binding site [polypeptide binding]"
                     /db_xref="CDD:269998"
     Region          2137..2253
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2395..2456
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2466..2521
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2689..2805
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2828..2986
                     /region_name="cyclophilin_ABH_like"
                     /note="Cyclophilin A, B and H-like cyclophilin-type
                     peptidylprolyl cis- trans isomerase (PPIase) domain. This
                     family represents the archetypal cystolic cyclophilin
                     similar to human cyclophilins A, B and H. PPIase is an
                     enzyme which accelerates protein folding...; cd01926"
                     /db_xref="CDD:238907"
     Site            order(2878..2879,2884,2935,2937,2945)
                     /site_type="active"
                     /db_xref="CDD:238907"
     CDS             1..2989
                     /gene="ranbp2"
                     /coded_by="XM_026272710.1:128..9097"
                     /db_xref="GeneID:113109137"
ORIGIN      
        1 mrrskadver yissvqnasp sqktktlkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrkdelaev ftemrahlyl yagtlllkra
      301 qdgpqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqiqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvvqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkyltqi
      721 yqasaedlek lpvsmeevmd llnevnqqlv gevdedqley pvtsspgqpt eghvkfstps
      781 ssksvtspsk rsvfspktpp hwvedqksll qmlcqqveal knevhdlrhn spdatassyr
      841 myrdnyaaeg lqetfpaaqt fhgvpltvat tgpsvyynqs paynsqyllr taanvtptkg
      901 pvygmnrlpp qqhmyayqqs thtpplqstp acmypqeqvf gppirfespa tsllspysee
      961 yyghnvpqpt vnptlpepgy ftkpcpvtst qstrsteska vdpkisfgpq ftgepakvpn
     1021 fggvaagptt tsstafkfns nfksndgdft fssaqvknse sllglltsdi ppkaevssep
     1081 khqtqdqlps qkevftfgsk saagfsftdg apnkmsifgn tdqrfsftsg tkttlgnsea
     1141 reeksgesdn dgthveeded gphfepivpl pdkvdvktge eeeeemfckr aklfrfdset
     1201 kewkergigs ikilkhkssg kvrllmrreq vlkicanhyi tadmvlkpna gsdkswvwya
     1261 mdyadempkt eqlairfkta deatlfkvkf eeaqkflses pqgqqtekks etpkpqvssk
     1321 evdlktlfsk kagewdcdvc cvrnaptsav cvacnsaaps taqvkpveep kgsgpvappa
     1381 klfsfglsgd saksatstdi cskgftfgsa sfkfgsndav etsagfgaqa ekntsqtdap
     1441 qrekvsaapa vpfgtgfgav dtstgfgaqa ekktsqadap qrekvstapa vpfgtgfgav
     1501 dtstgfgaqa ekktsqadap qrekvsaapa vpfgtgfgaq fakkdgqwdc dsclvrndas
     1561 atecvsckap cstvktnaas kgglaamfgk kagqwdcdtc lvrnegsssh cvscqtanpn
     1621 mknktsaaps sssftfsfgs sssqpaatgf kanfnpgpaf qfgtskekts leafkfesst
     1681 teaekssgss tfafsmptpv ggfkfgiaes eakpsdgqsq ngsasgllkn iaahhkeken
     1741 ekeaapssse qsvdsdsqdn nplftgkpnt fsfadlaktq gsfqfgqedp tfkgfagage
     1801 plftglypgp kadtsvdqdd emykteendn iqfepvvqmp ekvdlvtgee dekvlysqrv
     1861 klfrfdtetn qwkergvgnl kllknnqngr lrvlmrreqv lkvcanhwit ttmnlkplsg
     1921 sdrawmwlas dfsdgdakle qlaakfktpe laeefklkfe esqrllldip lqtphkltnt
     1981 grtahliqka eemksglkdl ksfltsqnkd desadtshst savvvkldse gtahtlewdn
     2041 ydlheevhkd ygsssvrdtp lqpdpvaknl frfgesssgf sfcfqpilsp skspsklnqs
     2101 qasigtddeq evsqeeerdg qyfepvvplp dlvevstgee neqvlfshra klyrydkdln
     2161 qwkergigdl kilqhyetkr vrlvmrrdqv lklcanhwiv snmklepmkg aekawiwsaf
     2221 dfaegqgkve qlavrfklqe tanafseife eaktaqekdt lltpfsaklp astqemlcgk
     2281 aavavleett kertgisees spkldqtpqs tknvvsppnl edeeagasrl ktsgaavasq
     2341 ssvqtpfsip trsldfrlfk nnpmafwtct sanqsearvy spsekksaqd vsdddieivf
     2401 eckptraqae laarlmlppt ffcyknspgy isdedsdded fesavrnlkg klyvdgadga
     2461 sdhdsevtlv wekrptadee qrarrlllpp tflcgvssds eaeaeklddf stevqkvqqa
     2521 qvkpvrwesg pqeisvsssa pqdtqvkpvr wesgpqeisg sssapqdtqv kpepsdggae
     2581 erqtdgsrpi dlstkrsses dsstatalsf gftsaagfsf aelaktsgef afgkkdagfs
     2641 wsgagasvfg saaaqtkeae eedsddetph sdeihfepiv slpevevrsg eedeeilfke
     2701 raklyrwdre lnqwkergvg dikilfhpek ksyrllmrre qvlkvcanht ispgielkpm
     2761 ntsanalvwt atdysegdgk veqlaakfkt pelaesfrra ftdtqtrmsq tdaaqtsaae
     2821 alsrdsnpvv ffdisideeh agrvvmelfa hivprtaenf ralctgekgf gyrrsvfhri
     2881 ipdfmcqggd ftshdgtggr siyggkfede sfevrhtgpg llsmanrgrd tnnsqffitl
     2941 kkaehldfkh vafgfvkdgm dvvrrmgelg tkdgkpthti sisecgqil
//
LOCUS       XP_026128496            2963 aa            linear   VRT 18-JUN-2025
DEFINITION  RANBP2-like and GRIP domain-containing protein 5/6 isoform X6
            [Carassius auratus].
ACCESSION   XP_026128496
VERSION     XP_026128496.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272711.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2963
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2963
                     /product="RANBP2-like and GRIP domain-containing protein
                     5/6 isoform X6"
                     /calculated_mol_wt=327634
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1178..1294
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1331..1360
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1335..1354
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1387..1414
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1439..1468
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1500..1524
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1544..1570
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1548..1567
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1591..1620
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1595..1614
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1847..1963
                     /region_name="RanBD2_RanBP2-like"
                     /note="Ran-binding protein 2, Ran binding domain repeat 2;
                     cd13177"
                     /db_xref="CDD:269998"
     Site            order(1861,1863..1865,1870..1875,1892,1894,1896..1897,
                     1899,1901..1903,1906,1908,1912,1916,1926,1928,1941,1945)
                     /site_type="other"
                     /note="putative RAN binding site [polypeptide binding]"
                     /db_xref="CDD:269998"
     Region          2137..2253
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2369..2430
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2440..2495
                     /region_name="IR1-M"
                     /note="Nup358/RanBP2 E3 ligase domain; pfam12185"
                     /db_xref="CDD:463488"
     Region          2663..2779
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          2802..2960
                     /region_name="cyclophilin_ABH_like"
                     /note="Cyclophilin A, B and H-like cyclophilin-type
                     peptidylprolyl cis- trans isomerase (PPIase) domain. This
                     family represents the archetypal cystolic cyclophilin
                     similar to human cyclophilins A, B and H. PPIase is an
                     enzyme which accelerates protein folding...; cd01926"
                     /db_xref="CDD:238907"
     Site            order(2852..2853,2858,2909,2911,2919)
                     /site_type="active"
                     /db_xref="CDD:238907"
     CDS             1..2963
                     /gene="ranbp2"
                     /coded_by="XM_026272711.1:128..9019"
                     /db_xref="GeneID:113109137"
ORIGIN      
        1 mrrskadver yissvqnasp sqktktlkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrkdelaev ftemrahlyl yagtlllkra
      301 qdgpqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqiqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvvqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkyltqi
      721 yqasaedlek lpvsmeevmd llnevnqqlv gevdedqley pvtsspgqpt eghvkfstps
      781 ssksvtspsk rsvfspktpp hwvedqksll qmlcqqveal knevhdlrhn spdatassyr
      841 myrdnyaaeg lqetfpaaqt fhgvpltvat tgpsvyynqs paynsqyllr taanvtptkg
      901 pvygmnrlpp qqhmyayqqs thtpplqstp acmypqeqvf gppirfespa tsllspysee
      961 yyghnvpqpt vnptlpepgy ftkpcpvtst qstrsteska vdpkisfgpq ftgepakvpn
     1021 fggvaagptt tsstafkfns nfksndgdft fssaqvknse sllglltsdi ppkaevssep
     1081 khqtqdqlps qkevftfgsk saagfsftdg apnkmsifgn tdqrfsftsg tkttlgnsea
     1141 reeksgesdn dgthveeded gphfepivpl pdkvdvktge eeeeemfckr aklfrfdset
     1201 kewkergigs ikilkhkssg kvrllmrreq vlkicanhyi tadmvlkpna gsdkswvwya
     1261 mdyadempkt eqlairfkta deatlfkvkf eeaqkflses pqgqqtekks etpkpqvssk
     1321 evdlktlfsk kagewdcdvc cvrnaptsav cvacnsaaps taqvkpveep kgsgpvappa
     1381 klfsfglsgd saksatstdi cskgftfgsa sfkfgsndav etsagfgaqa ekntsqtdap
     1441 qrekvsaapa vpfgtgfgav dtstgfgaqa ekktsqadap qrekvstapa vpfgtgfgav
     1501 dtstgfgaqa ekktsqadap qrekvsaapa vpfgtgfgaq fakkdgqwdc dsclvrndas
     1561 atecvsckap cstvktnaas kgglaamfgk kagqwdcdtc lvrnegsssh cvscqtanpn
     1621 mknktsaaps sssftfsfgs sssqpaatgf kanfnpgpaf qfgtskekts leafkfesst
     1681 teaekssgss tfafsmptpv ggfkfgiaes eakpsdgqsq ngsasgllkn iaahhkeken
     1741 ekeaapssse qsvdsdsqdn nplftgkpnt fsfadlaktq gsfqfgqedp tfkgfagage
     1801 plftglypgp kadtsvdqdd emykteendn iqfepvvqmp ekvdlvtgee dekvlysqrv
     1861 klfrfdtetn qwkergvgnl kllknnqngr lrvlmrreqv lkvcanhwit ttmnlkplsg
     1921 sdrawmwlas dfsdgdakle qlaakfktpe laeefklkfe esqrllldip lqtphkltnt
     1981 grtahliqka eemksglkdl ksfltsqnkd desadtshst savvvkldse gtahtlewdn
     2041 ydlheevhkd ygsssvrdtp lqpdpvaknl frfgesssgf sfcfqpilsp skspsklnqs
     2101 qasigtddeq evsqeeerdg qyfepvvplp dlvevstgee neqvlfshra klyrydkdln
     2161 qwkergigdl kilqhyetkr vrlvmrrdqv lklcanhwiv snmklepmkg aekawiwsaf
     2221 dfaegqgkve qlavrfklqe tanafseife eaktaqekdt lltpfsaklp astqemlcgk
     2281 aavavleett kertgisees spkldqtpqs tknvvsppnl edeeagasrl ktsgaavasq
     2341 ssvqtpfsip triyspsekk saqdvsdddi eivfeckptr aqaelaarlm lpptffcykn
     2401 spgyisdeds ddedfesavr nlkgklyvdg adgasdhdse vtlvwekrpt adeeqrarrl
     2461 llpptflcgv ssdseaeaek lddfstevqk vqqaqvkpvr wesgpqeisv sssapqdtqv
     2521 kpvrwesgpq eisgsssapq dtqvkpepsd ggaeerqtdg srpidlstkr ssesdsstat
     2581 alsfgftsaa gfsfaelakt sgefafgkkd agfswsgaga svfgsaaaqt keaeeedsdd
     2641 etphsdeihf epivslpeve vrsgeedeei lfkeraklyr wdrelnqwke rgvgdikilf
     2701 hpekksyrll mrreqvlkvc anhtispgie lkpmntsana lvwtatdyse gdgkveqlaa
     2761 kfktpelaes frraftdtqt rmsqtdaaqt saaealsrds npvvffdisi deehagrvvm
     2821 elfahivprt aenfralctg ekgfgyrrsv fhriipdfmc qggdftshdg tggrsiyggk
     2881 fedesfevrh tgpgllsman rgrdtnnsqf fitlkkaehl dfkhvafgfv kdgmdvvrrm
     2941 gelgtkdgkp thtisisecg qil
//
LOCUS       XP_026128497            2161 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 SUMO-protein ligase RanBP2-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128497
VERSION     XP_026128497.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272712.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2161
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2161
                     /product="E3 SUMO-protein ligase RanBP2-like isoform X1"
                     /calculated_mol_wt=236076
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1170..1286
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1323..1352
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1327..1346
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275376"
     Region          1656..1682
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1660..1679
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1703..1732
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1707..1726
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          <1948..1976
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     CDS             1..2161
                     /gene="LOC113109138"
                     /coded_by="XM_026272712.1:93..6578"
                     /db_xref="GeneID:113109138"
ORIGIN      
        1 mrrskadver yissvqsasp sqktrplkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrtdelaev ftemrahlyl yagtlllkra
      301 qdgaqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqtqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvmqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkylthi
      721 yrakedlekl pvsmeevmdl lnevnqqlvg evdedqlefp vtsspgqpte ghvkfstpss
      781 sksvtspskr svfspktpph wvedqksllq mlcqqvealk sevhghnssd atassyrmyr
      841 dnyaadglqe tfpavqtfhg vpfpvattgp svyynqspay nsqyllrtaa nvtptkgpvy
      901 gmnrlppqqh myayqqstht pplqstpacm ypqeqvfgpp irfespatsl lspyseeyyg
      961 hnvpqptdnp tlpepgyftk pcpvtstqpt rsteskavdp kisfgpqftg ehakvpnfgg
     1021 vaagptafkf nsnfksndgd ftfssaqvkn sesllgllts dippkaevss epkhqtqdql
     1081 psqkevftfg sksaagfsft dgapnkmsif gntdqrfsft sgtkttlgns eareeksges
     1141 dndgthvedd edgphfepiv plpdkvdvkt geeeeeemfc kraklfrfds etkewkergi
     1201 gsfkilkhks sgkvrllmrr eqvlkicanh yitadmvlkp nagsdkswvw yamdyademp
     1261 kteqlairfk tadeatlfkv kfeeaqkfls espqgqqtek ksetpkpqvs skemdlktlf
     1321 skkagewdcd vccvrnapts avcvacnsaa pstaqvkpve epkgsgpvap paklfsfglf
     1381 gdsaksatsi disskgftfe svsfkfgsnd avetsagfga qvekktsqad aaqqekvsaa
     1441 pavpfgtgfg avetsagfga qaekktsqvd apereivsaa pavpfgtgfg avetsagfga
     1501 qaekktsqad aaqrekvsta pavpfgtgfg avetsagfga qaekktsqfd aperdkvsaa
     1561 pavpfgtgfg avetsagfga qaekktsqgd aperdkvsaa pavpfgtgfg avetsagfga
     1621 qaekktsqtd apqrekvsaa pavpfgtgfg aqfakkdgqw dcdsclvrnd asatecvsck
     1681 apcstvktna askgglaamf gkkagqwdcd tclvrnegss shcvscqtan pnmknktsaa
     1741 pssssftfsf gsssnqpaat gfkanfnpgp afqfgtskek ssleafkfes stteaekssg
     1801 sstfafsmpt pvggfkfgia eseanpsdgq sqngsasdll kniaahhkek enekeaapss
     1861 seqfvdsdsq dnsplftgkp ntfifvdlak tqgsfqfgqe dptfkgfaga aeqpftgfyp
     1921 gpkadtsvdq ddeiykteen dniqfepegq gkveqledqf kqqetanafn eieeaktaqe
     1981 kdtlltpfsa rvpastqeml cgkaavavle ettkertgis eesspkldqt pqctknvvss
     2041 pklvfgfgsp lpsnekslvv issseeeevg asrlktfgpa vtsqssvets ssiptsmsfg
     2101 lasagelsfa elaklseefa fakrddnftw pdagapvfrs patqnegdea eeegsddknt
     2161 s
//
LOCUS       XP_026128498            2121 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 SUMO-protein ligase RanBP2-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128498
VERSION     XP_026128498.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272713.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2121
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2121
                     /product="E3 SUMO-protein ligase RanBP2-like isoform X2"
                     /calculated_mol_wt=232155
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1170..1286
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1323..1352
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1327..1346
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275376"
     Region          1616..1642
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1620..1639
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1663..1692
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1667..1686
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          <1908..1936
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     CDS             1..2121
                     /gene="LOC113109138"
                     /coded_by="XM_026272713.1:92..6457"
                     /db_xref="GeneID:113109138"
ORIGIN      
        1 mrrskadver yissvqsasp sqktrplkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrtdelaev ftemrahlyl yagtlllkra
      301 qdgaqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqtqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvmqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkylthi
      721 yrakedlekl pvsmeevmdl lnevnqqlvg evdedqlefp vtsspgqpte ghvkfstpss
      781 sksvtspskr svfspktpph wvedqksllq mlcqqvealk sevhghnssd atassyrmyr
      841 dnyaadglqe tfpavqtfhg vpfpvattgp svyynqspay nsqyllrtaa nvtptkgpvy
      901 gmnrlppqqh myayqqstht pplqstpacm ypqeqvfgpp irfespatsl lspyseeyyg
      961 hnvpqptdnp tlpepgyftk pcpvtstqpt rsteskavdp kisfgpqftg ehakvpnfgg
     1021 vaagptafkf nsnfksndgd ftfssaqvkn sesllgllts dippkaevss epkhqtqdql
     1081 psqkevftfg sksaagfsft dgapnkmsif gntdqrfsft sgtkttlgns eareeksges
     1141 dndgthvedd edgphfepiv plpdkvdvkt geeeeeemfc kraklfrfds etkewkergi
     1201 gsfkilkhks sgkvrllmrr eqvlkicanh yitadmvlkp nagsdkswvw yamdyademp
     1261 kteqlairfk tadeatlfkv kfeeaqkfls espqgqqtek ksetpkpqvs skemdlktlf
     1321 skkagewdcd vccvrnapts avcvacnsaa pstaqvkpve epkgsgpvap paklfsfglf
     1381 gdsaksatsi disskgftfe svsfkfgsnd avetsagfga qaekktsqvd apereivsaa
     1441 pavpfgtgfg avetsagfga qaekktsqad aaqrekvsta pavpfgtgfg avetsagfga
     1501 qaekktsqfd aperdkvsaa pavpfgtgfg avetsagfga qaekktsqgd aperdkvsaa
     1561 pavpfgtgfg avetsagfga qaekktsqtd apqrekvsaa pavpfgtgfg aqfakkdgqw
     1621 dcdsclvrnd asatecvsck apcstvktna askgglaamf gkkagqwdcd tclvrnegss
     1681 shcvscqtan pnmknktsaa pssssftfsf gsssnqpaat gfkanfnpgp afqfgtskek
     1741 ssleafkfes stteaekssg sstfafsmpt pvggfkfgia eseanpsdgq sqngsasdll
     1801 kniaahhkek enekeaapss seqfvdsdsq dnsplftgkp ntfifvdlak tqgsfqfgqe
     1861 dptfkgfaga aeqpftgfyp gpkadtsvdq ddeiykteen dniqfepegq gkveqledqf
     1921 kqqetanafn eieeaktaqe kdtlltpfsa rvpastqeml cgkaavavle ettkertgis
     1981 eesspkldqt pqctknvvss pklvfgfgsp lpsnekslvv issseeeevg asrlktfgpa
     2041 vtsqssvets ssiptsmsfg lasagelsfa elaklseefa fakrddnftw pdagapvfrs
     2101 patqnegdea eeegsddknt s
//
LOCUS       XP_026128499            2096 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 SUMO-protein ligase RanBP2-like isoform X3 [Carassius auratus].
ACCESSION   XP_026128499
VERSION     XP_026128499.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272714.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2096
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2096
                     /product="E3 SUMO-protein ligase RanBP2-like isoform X3"
                     /calculated_mol_wt=229104
     Region          3..185
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Site            order(34..35,37,61,64..65,68..69,71..72,95,98..99,
                     102..103,106)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          59..89
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          94..123
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          1170..1286
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     Region          1323..1352
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1327..1346
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275376"
     Region          1656..1682
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1660..1679
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          1703..1732
                     /region_name="zf-RanBP"
                     /note="Zn-finger in Ran binding protein and others;
                     pfam00641"
                     /db_xref="CDD:395516"
     Region          1707..1726
                     /region_name="RanBP2-type Zn finger"
                     /note="RanBP2-type Zn finger [structural motif]"
                     /db_xref="CDD:275375"
     Region          <1948..1976
                     /region_name="PH-like"
                     /note="Pleckstrin homology-like domain; cl17171"
                     /db_xref="CDD:473070"
     CDS             1..2096
                     /gene="LOC113109138"
                     /coded_by="XM_026272714.1:92..6382"
                     /db_xref="GeneID:113109138"
ORIGIN      
        1 mrrskadver yissvqsasp sqktrplkgf lfaklyfeak eyelakrhvs eyltvqpkdp
       61 kahkflgqlf erdgetdkav gcykrsvdln paqhdlvlkv aellcskpqh dsraefwvek
      121 aarllpghpa vfnlreklls aqsgsnqlye llqaelklrp tdtyinqklv qlysaegrle
      181 davkhclave ktgilrhcle wyqllvstlq eylcqpsvss neqasrkfhk elllaqcsrv
      241 rltltlkdce estaalwsfd camqdlknta tnrtdelaev ftemrahlyl yagtlllkra
      301 qdgaqqwrtv ldlaalcyli syqaprpkar slkseqvshe plellacdrq sqaghmllnl
      361 sqdveqllkd vvesfgnrsg pghlfdqlfg aqtqeqhsfi cnddihvlsv hapkaadlak
      421 wdsgavmlha gdlqqlvwlg lqwalmgqsv slqdwlkqlf prltletskl dtnapesicl
      481 ldlevfvsgv vfcsqtqlqe rvkmtscsqp leprclplhi mkllssdrqr ewwdavysli
      541 hkraqpgtsa klrlvmqhgl gtlragekhg lqpallihwa khltdmaerg nsyydqkeya
      601 grsvhywkvv lpllekvrhk rsipeplqpm fmhfqskdiq psqvrvyeed atisfatlld
      661 iegnteeais kleqlnslss nwhlakiyqr lseeagngle etqgrctdfl lkfrkylthi
      721 yrakedlekl pvsmeevmdl lnevnqqlvg evdedqlefp vtsspgqpte ghvkfstpss
      781 sksvtspskr svfspktpph wvedqksllq mlcqqvealk sevhghnssd atassyrmyr
      841 dnyaadglqe tfpavqtfhg vpfpvattgp svyynqspay nsqyllrtaa nvtptkgpvy
      901 gmnrlppqqh myayqqstht pplqstpacm ypqeqvfgpp irfespatsl lspyseeyyg
      961 hnvpqptdnp tlpepgyftk pcpvtstqpt rsteskavdp kisfgpqftg ehakvpnfgg
     1021 vaagptafkf nsnfksndgd ftfssaqvkn sesllgllts dippkaevss epkhqtqdql
     1081 psqkevftfg sksaagfsft dgapnkmsif gntdqrfsft sgtkttlgns eareeksges
     1141 dndgthvedd edgphfepiv plpdkvdvkt geeeeeemfc kraklfrfds etkewkergi
     1201 gsfkilkhks sgkvrllmrr eqvlkicanh yitadmvlkp nagsdkswvw yamdyademp
     1261 kteqlairfk tadeatlfkv kfeeaqkfls espqgqqtek ksetpkpqvs skemdlktlf
     1321 skkagewdcd vccvrnapts avcvacnsaa pstaqvkpve epkgsgpvap paklfsfglf
     1381 gdsaksatsi disskgftfe svsfkfgsnd avetsagfga qvekktsqad aaqqekvsaa
     1441 pavpfgtgfg avetsagfga qaekktsqvd apereivsaa pavpfgtgfg avetsagfga
     1501 qaekktsqad aaqrekvsta pavpfgtgfg avetsagfga qaekktsqfd aperdkvsaa
     1561 pavpfgtgfg avetsagfga qaekktsqgd aperdkvsaa pavpfgtgfg avetsagfga
     1621 qaekktsqtd apqrekvsaa pavpfgtgfg aqfakkdgqw dcdsclvrnd asatecvsck
     1681 apcstvktna askgglaamf gkkagqwdcd tclvrnegss shcvscqtan pnmknktsaa
     1741 pssssftfsf gsssnqpaat gfkanfnpgp afqfgtskek ssleafkfes stteaekssg
     1801 sstfafsmpt pvggfkfgia eseanpsdgq sqngsasdll kniaahhkek enekeaapss
     1861 seqfvdsdsq dnsplftgkp ntfifvdlak tqgsfqfgqe dptfkgfaga aeqpftgfyp
     1921 gpkadtsvdq ddeiykteen dniqfepegq gkveqledqf kqqetanafn eieeaktaqe
     1981 kdtlltpfsa rvpastqeml cgkaavavle ettkertgis eesspkldqt pqctknvvss
     2041 pklvfgfgsp lpsnekslvv issseeeevg asrlktfgpa vtsqssvets ssipts
//
LOCUS       XP_026128500             440 aa            linear   VRT 18-JUN-2025
DEFINITION  LIM and senescent cell antigen-like-containing domain protein 2
            [Carassius auratus].
ACCESSION   XP_026128500
VERSION     XP_026128500.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272715.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..440
                     /product="LIM and senescent cell antigen-like-containing
                     domain protein 2"
                     /calculated_mol_wt=50606
     Region          118..176
                     /region_name="LIM1_PINCH"
                     /note="The first LIM domain of protein PINCH; cd09331"
                     /db_xref="CDD:188717"
     Site            order(118,121,140,143,146,149,167,170)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:188717"
     Site            order(120..121,123,145,147..151,161..162,164,169..170,
                     172..176)
                     /site_type="other"
                     /note="ILK binding interface"
                     /db_xref="CDD:188717"
     Region          179..230
                     /region_name="LIM2_PINCH"
                     /note="The second LIM domain of protein PINCH; cd09332"
                     /db_xref="CDD:188718"
     Site            order(179,182,199,202,205,208,226,229)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:188718"
     Region          243..293
                     /region_name="LIM3_PINCH"
                     /note="The third LIM domain of protein PINCH; cd09333"
                     /db_xref="CDD:188719"
     Site            order(243,246,263,266,269,272,289,292)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:188719"
     Region          299..352
                     /region_name="LIM4_PINCH"
                     /note="The fourth LIM domain of protein PINCH; cd09334"
                     /db_xref="CDD:188720"
     Site            order(300,304..307)
                     /site_type="other"
                     /note="N(i)ck binding interface"
                     /db_xref="CDD:188720"
     Site            order(301,304,321,324,327,330,348,351)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:188720"
     Region          360..413
                     /region_name="LIM5_PINCH"
                     /note="The fifth LIM domain of protein PINCH; cd09335"
                     /db_xref="CDD:188721"
     Site            order(360,363,380,383,386,389,408,411)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:188721"
     CDS             1..440
                     /gene="lims2"
                     /coded_by="XM_026272715.1:2..1324"
                     /db_xref="GeneID:113109140"
ORIGIN      
        1 mhsallllgt qfnceserrt qanlsksavm nlghsqrmsk hqdsvthddr trsildseal
       61 qpqlthsrli meedspersi nglqdteipk rsdvkvykef cdfyvrynmt nalanaicer
      121 ckasftptek ivnsngelyh eqcfvcaqcf qqfleglfye fedrkycehd fqmlfapccr
      181 qcgefiigrv ikamnsswhp dcfccdlcqa vladigfvkn tgrhlcrpch erekahslgk
      241 yicqkcqaii ddiplifknd pyhpdhfscs ncgkeltsea relrgelycl pchdklgvpi
      301 cgacrrpieg rvvnamgkqw hvehfvcakc ekpflghrhy erkglaycet hynqlfgevc
      361 fhcnraiegd vvsalnkawc vkcfgcstcn skltlkdrfv eldlkpvckh cyervpdelk
      421 rrlskqdskd trkkkmpicl
//
LOCUS       XP_026128501             728 aa            linear   VRT 18-JUN-2025
DEFINITION  ribosomal RNA processing protein 1 homolog A isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128501
VERSION     XP_026128501.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272716.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..728
                     /product="ribosomal RNA processing protein 1 homolog A
                     isoform X1"
                     /calculated_mol_wt=82044
     Region          9..215
                     /region_name="Nop52"
                     /note="Nucleolar protein,Nop52; pfam05997"
                     /db_xref="CDD:461800"
     CDS             1..728
                     /gene="rrp1"
                     /coded_by="XM_026272716.1:92..2278"
                     /db_xref="GeneID:113109141"
ORIGIN      
        1 mastqeaeii faqklasnek pvrskalvkl rkyiiarser aegfseeell kiwkglfycm
       61 wmqdkpllqe elstkisrll hsfrtldsqf lylktflltm krewngidrl rmdkfyqlvr
      121 fvfrevfeml krqqwesrlv tqflqlfsaq llhsssvapa glvlhvldly mtelalvgsa
      181 eltaeqnqtf iepffktvak tkdrvllkai gsnifntivd qvpfaiqdlq remgqsaeld
      241 ssdeseeqqh tdetettals hkptdceeed alsedadded tcgpvlqfdy gaiadslfam
      301 ashsniqsfn rskiykfvki frdlsegvfp qdevekvsse eedvddngrk krkrrrqrnk
      361 gmkdeeslkk seadlsesta asdhtdtsqd ttpkkkskkk kkrsvegqqt apsetqdstg
      421 aaeeklessv cdsqqesscs epalqlkkkq rrkrtvsgkt cetaeetdhc sqmdisitsa
      481 eivtagpqkk kqklkkkakg aecevtgsvs dvpavdvsta sqtqthsaka spktpvkkrk
      541 qkdvvsdlpe tetngdaetv ptegplrtkk ikqkpssvrv raerkrrame devkpaqlng
      601 hteqtrvkrh ktitafcqqe aeedvkvkef vlrqkraptp ifckaaghth vaskkvlpas
      661 ksemkkvtfg lknnktmefr ktdqssllsp arqsavpfdp krtpksgvlk sptsspalrk
      721 ramaadff
//
LOCUS       XP_026128502             727 aa            linear   VRT 18-JUN-2025
DEFINITION  ribosomal RNA processing protein 1 homolog A isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128502
VERSION     XP_026128502.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272717.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..727
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..727
                     /product="ribosomal RNA processing protein 1 homolog A
                     isoform X2"
                     /calculated_mol_wt=81973
     Region          9..215
                     /region_name="Nop52"
                     /note="Nucleolar protein,Nop52; pfam05997"
                     /db_xref="CDD:461800"
     CDS             1..727
                     /gene="rrp1"
                     /coded_by="XM_026272717.1:91..2274"
                     /db_xref="GeneID:113109141"
ORIGIN      
        1 mastqeaeii faqklasnek pvrskalvkl rkyiiarser aegfseeell kiwkglfycm
       61 wmqdkpllqe elstkisrll hsfrtldsqf lylktflltm krewngidrl rmdkfyqlvr
      121 fvfrevfeml krqqwesrlv tqflqlfsaq llhsssvapa glvlhvldly mtelalvgsa
      181 eltaeqnqtf iepffktvak tkdrvllkai gsnifntivd qvpfaiqdlq remgqsaeld
      241 ssdeseeqqh tdetettals hkptdceeed alsedadded tcgpvlqfdy gaiadslfam
      301 ashsniqsfn rskiykfvki frdlsegvfp qdevekvsse eedvddngrk krkrrrqrnk
      361 gmkdeeslkk sedlsestaa sdhtdtsqdt tpkkkskkkk krsvegqqta psetqdstga
      421 aeeklessvc dsqqesscse palqlkkkqr rkrtvsgktc etaeetdhcs qmdisitsae
      481 ivtagpqkkk qklkkkakga ecevtgsvsd vpavdvstas qtqthsakas pktpvkkrkq
      541 kdvvsdlpet etngdaetvp tegplrtkki kqkpssvrvr aerkrramed evkpaqlngh
      601 teqtrvkrhk titafcqqea eedvkvkefv lrqkraptpi fckaaghthv askkvlpask
      661 semkkvtfgl knnktmefrk tdqssllspa rqsavpfdpk rtpksgvlks ptsspalrkr
      721 amaadff
//
LOCUS       XP_026128503             723 aa            linear   VRT 18-JUN-2025
DEFINITION  ribosomal RNA processing protein 1 homolog A isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128503
VERSION     XP_026128503.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272718.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..723
                     /product="ribosomal RNA processing protein 1 homolog A
                     isoform X3"
                     /calculated_mol_wt=81467
     Region          9..215
                     /region_name="Nop52"
                     /note="Nucleolar protein,Nop52; pfam05997"
                     /db_xref="CDD:461800"
     CDS             1..723
                     /gene="rrp1"
                     /coded_by="XM_026272718.1:90..2261"
                     /db_xref="GeneID:113109141"
ORIGIN      
        1 mastqeaeii faqklasnek pvrskalvkl rkyiiarser aegfseeell kiwkglfycm
       61 wmqdkpllqe elstkisrll hsfrtldsqf lylktflltm krewngidrl rmdkfyqlvr
      121 fvfrevfeml krqqwesrlv tqflqlfsaq llhsssvapa glvlhvldly mtelalvgsa
      181 eltaeqnqtf iepffktvak tkdrvllkai gsnifntivd qvpfaiqdlq remgqsaeld
      241 ssdeseeqqh tdetettals hkptdceeed alsedadded tcgpvlqfdy gaiadslfam
      301 ashsniqsfn rskiykfvki frdlsegvfp qdevekvsse eedvddngrk krkrrrqrnk
      361 gmkdeeslkk seadlsesta asdhtdtsqd ttpkkkskkk kkrsvegqqt apsetqdstg
      421 aaeeklessv cdsqqesscs epalqlkkkq rrkrtvsgkt cetaeetdhc sqmdisitsa
      481 eivtagpqkk kqklkkkakg aecevtgsvs dvpavdvsta sqtqthsaka spktpvkkrk
      541 qkdvvsdlpe tetngdaetv ptegplrtkk ikqkpssvrv raerkrrame devkpaqlng
      601 hteqtrvkrh ktiteaeedv kvkefvlrqk raptpifcka aghthvaskk vlpasksemk
      661 kvtfglknnk tmefrktdqs sllsparqsa vpfdpkrtpk sgvlksptss palrkramaa
      721 dff
//
LOCUS       XP_026128504             687 aa            linear   VRT 18-JUN-2025
DEFINITION  ribosomal RNA processing protein 1 homolog A isoform X4 [Carassius
            auratus].
ACCESSION   XP_026128504
VERSION     XP_026128504.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272719.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..687
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..687
                     /product="ribosomal RNA processing protein 1 homolog A
                     isoform X4"
                     /calculated_mol_wt=77435
     Region          9..215
                     /region_name="Nop52"
                     /note="Nucleolar protein,Nop52; pfam05997"
                     /db_xref="CDD:461800"
     CDS             1..687
                     /gene="rrp1"
                     /coded_by="XM_026272719.1:92..2155"
                     /db_xref="GeneID:113109141"
ORIGIN      
        1 mastqeaeii faqklasnek pvrskalvkl rkyiiarser aegfseeell kiwkglfycm
       61 wmqdkpllqe elstkisrll hsfrtldsqf lylktflltm krewngidrl rmdkfyqlvr
      121 fvfrevfeml krqqwesrlv tqflqlfsaq llhsssvapa glvlhvldly mtelalvgsa
      181 eltaeqnqtf iepffktvak tkdrvllkai gsnifntivd qvpfaiqdlq remgqsaeld
      241 ssdeseeqqh tdetettals hkptdceeed alsedadded tcgpvlqfdy gaiadslfam
      301 ashsniqsfn rskiykfvki frdlsegvfp qdevekvsse eedvddngrk krkrrrqrnk
      361 gmkdeeslkk seadlsesta asdhtdtsqd ttpkkkskkk kkrsvegqqt apsetqdstg
      421 aaeeklessv cdsqqesscs epalqlkkkq rrkrtvsgkt cetaeetdhc sqmdisitsa
      481 eivtagpqkk kqklkkkakg aecevtgsvs dvpavdvsta sqtqthsaka spktpvkkrk
      541 qkdvvsdlpe tetngdaetv ptegplrtkk ikqkpssvrv raerkrrame devkpaqlng
      601 hteqtrvkrh ktitvlpask semkkvtfgl knnktmefrk tdqssllspa rqsavpfdpk
      661 rtpksgvlks ptsspalrkr amaadff
//
LOCUS       XP_026128505             252 aa            linear   VRT 18-JUN-2025
DEFINITION  claudin-10-like [Carassius auratus].
ACCESSION   XP_026128505
VERSION     XP_026128505.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272720.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..252
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..252
                     /product="claudin-10-like"
                     /calculated_mol_wt=27518
     Region          4..185
                     /region_name="PMP22_Claudin"
                     /note="PMP-22/EMP/MP20/Claudin family; cl21598"
                     /db_xref="CDD:473919"
     CDS             1..252
                     /gene="LOC113109142"
                     /coded_by="XM_026272720.1:235..993"
                     /db_xref="GeneID:113109142"
ORIGIN      
        1 mrksliqvfg flistfgwlf vsctlamdyw rifyvggkgg nwmikgtwyw snlwkdcvvd
       61 tssvtncrdy dvlwavtpyv qgvrglllia mslgliaavl cfigmdctyi ggsekhkdri
      121 lffgaafhfv ggvsalaayc lytnrvvsta lspaadrsim ryglgtpiff gligsffiil
      181 gsvlyavtii ansgwtvfgr kadappsska qytsayyaps rpsvhlsqss gsrvsrksrv
      241 tggnisprdt fv
//
LOCUS       XP_026128506             241 aa            linear   VRT 18-JUN-2025
DEFINITION  claudin-10 isoform X1 [Carassius auratus].
ACCESSION   XP_026128506
VERSION     XP_026128506.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272721.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..241
                     /product="claudin-10 isoform X1"
                     /calculated_mol_wt=25901
     Region          4..179
                     /region_name="PMP22_Claudin"
                     /note="PMP-22/EMP/MP20/Claudin family; cl21598"
                     /db_xref="CDD:473919"
     CDS             1..241
                     /gene="cldn10b"
                     /coded_by="XM_026272721.1:90..815"
                     /db_xref="GeneID:113109143"
ORIGIN      
        1 msnmareila filttsgwvl vsstlptdyw kvssidgtvi ttatfwsnlw ktcvtdstgv
       61 snckdfpsml aldgyiqvcr glmiaavclg ffasifalig mkctkiggpd qtkarivcls
      121 gitfmctglc slsacslyah ritseffdpm fvaqkyelga alfigwagst lcilggalfc
      181 lslsdgmsnn sspypsdrra fvnsgaslms rampqsqssh trrpppeysg pskhfdknay
      241 v
//
LOCUS       XP_026128507             240 aa            linear   VRT 18-JUN-2025
DEFINITION  claudin-10 isoform X2 [Carassius auratus].
ACCESSION   XP_026128507
VERSION     XP_026128507.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272722.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..240
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..240
                     /product="claudin-10 isoform X2"
                     /calculated_mol_wt=25814
     Region          4..179
                     /region_name="PMP22_Claudin"
                     /note="PMP-22/EMP/MP20/Claudin family; cl21598"
                     /db_xref="CDD:473919"
     CDS             1..240
                     /gene="cldn10b"
                     /coded_by="XM_026272722.1:91..813"
                     /db_xref="GeneID:113109143"
ORIGIN      
        1 msnmareila filttsgwvl vsstlptdyw kvssidgtvi ttatfwsnlw ktcvtdstgv
       61 snckdfpsml aldgyiqvcr glmiaavclg ffasifalig mkctkiggpd qtkarivcls
      121 gitfmctglc slsacslyah ritseffdpm fvaqkyelga alfigwagst lcilggalfc
      181 lslsdgmsnn spypsdrraf vnsgaslmsr ampqsqssht rrpppeysgp skhfdknayv
//
LOCUS       XP_026128508             247 aa            linear   VRT 18-JUN-2025
DEFINITION  claudin-10 [Carassius auratus].
ACCESSION   XP_026128508
VERSION     XP_026128508.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272723.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..247
                     /product="claudin-10"
                     /calculated_mol_wt=26816
     Region          8..183
                     /region_name="PMP22_Claudin"
                     /note="PMP-22/EMP/MP20/Claudin family; cl21598"
                     /db_xref="CDD:473919"
     CDS             1..247
                     /gene="cldn10c"
                     /coded_by="XM_026272723.1:25..768"
                     /db_xref="GeneID:113109144"
ORIGIN      
        1 mhyrtlmmyt eigcfvacvc gwilvcstmp tnywtysevd slvltsghyf snlwkdclsd
       61 stgvsdckef ptllalqtyi hlcrslvits iilglfgail alvgmkctkl ggseimnakv
      121 tfaagmnyll sglcgmfays wyahkvisef mdpnyrakkf elgsalfvgw ggsallvvgg
      181 lvfsitagke acrsssktqe msnhtppsnl seanqkthsp plspipdran qktskppkas
      241 havdayv
//
LOCUS       XP_026128509             557 aa            linear   VRT 18-JUN-2025
DEFINITION  putative phospholipase B-like 2 [Carassius auratus].
ACCESSION   XP_026128509
VERSION     XP_026128509.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272724.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..557
                     /product="putative phospholipase B-like 2"
                     /calculated_mol_wt=62471
     Region          53..551
                     /region_name="Phospholip_B"
                     /note="Phospholipase B; pfam04916"
                     /db_xref="CDD:461479"
     CDS             1..557
                     /gene="plbd2"
                     /coded_by="XM_026272724.1:117..1790"
                     /db_xref="GeneID:113109145"
ORIGIN      
        1 mkrcvcrgsm acyllffflc avhlsraqiy salydektsr lflreglqpn svavanftdd
       61 inntgwafle vstsggyndt lqayaagvve aavssqliyk hwmntlmgyc gpfshdvsyc
      121 qrlkdyitsn lqwvtqqmdt hadapywhqv rlsllqlrgl edgyngqidf psgsfsinpf
      181 gfllfqmggd ledleealnk sspsrsvgsg scsalikflp glkdllvshd twnnyqsmlr
      241 ilkrysltyr tapaekeiip griqvfssyp gtifsgddfy llssglvtle ttignsnaal
      301 wglvqprgav mewlrnivan rlapsgrawt difskynsgt ynnqwmvvdy kafvpgqgyt
      361 qpglftvleq ipgtivtadr teelfqtgyw asynipyfee vfnasggpel vqkygswfsf
      421 rdnpraqifr rnqslvtdme smvrlmrynn fqedplsrcd gcdpaqngen sisarsdlnp
      481 gngsypfgal kqrphggtdm kvtsaglfsh lellavsgpt wdqvpvfqws sspyssllhm
      541 ghpdrwdfqp vhvrwss
//
LOCUS       XP_026128510             506 aa            linear   VRT 18-JUN-2025
DEFINITION  aladin [Carassius auratus].
ACCESSION   XP_026128510
VERSION     XP_026128510.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272725.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..506
                     /product="aladin"
                     /calculated_mol_wt=54323
     Region          146..400
                     /region_name="WD40"
                     /note="WD40 domain, found in a number of eukaryotic
                     proteins that cover a wide variety of functions including
                     adaptor/regulatory modules in signal transduction,
                     pre-mRNA processing and cytoskeleton assembly; typically
                     contains a GH dipeptide 11-24 residues from...; cl29593"
                     /db_xref="CDD:475233"
     Region          150..187
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          191..237
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          241..277
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          285..319
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          325..374
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     CDS             1..506
                     /gene="aaas"
                     /coded_by="XM_026272725.1:141..1661"
                     /db_xref="GeneID:113109147"
ORIGIN      
        1 mcslgvfpap vtaaqtlfer nnellsaldp gehsqvcdlp spqftrdtlk ghsrpesssr
       61 safldqrdtl wmrsagawrd aglyglldei tnsadevprf lavgsscvla llrwassfhg
      121 slfphltlss demvaefsqm ldwsdsalrs fawhphtdkf avallddsik iyksnssptp
      181 tlkhrcqrsv calqwkplcg salaaacqsc lliwhvdpas lstrpssgca qvlshpghsp
      241 itsiawsptg sllvsaspvd tsmmvwdvaa esavplqrvg gggvthlsws pdgsrllaat
      301 psalfrvwet rmwtcerwpc lkgscqsacw spdggcllls mqgerviyal tfsdltggpk
      361 aasvvadlse ttfpgpdgdl tvggevcsls wdprgerlav llkgdsqavn hpsviavfkt
      421 rsspvfellp cgfvmgesga eprfmqfhph fqhgalltvc wsdgrishvp fyfssagllg
      481 gdsplqafas stadpssnkl yseqts
//
LOCUS       XP_026128511             906 aa            linear   VRT 18-JUN-2025
DEFINITION  mitogen-activated protein kinase kinase kinase 12 isoform X1
            [Carassius auratus].
ACCESSION   XP_026128511
VERSION     XP_026128511.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272726.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..906
                     /product="mitogen-activated protein kinase kinase kinase
                     12 isoform X1"
                     /calculated_mol_wt=99307
     Region          162..398
                     /region_name="STKc_MAP3K12_13"
                     /note="Catalytic domain of the Serine/Threonine Kinases,
                     Mitogen-Activated Protein Kinase Kinase Kinases 12 and 13;
                     cd14059"
                     /db_xref="CDD:270961"
     Site            order(162..166,170,181,183,205,221..224,228,230,267,269,
                     271..272,274,285,288,303..306)
                     /site_type="active"
                     /db_xref="CDD:270961"
     Site            order(162..166,170,181,183,205,221..224,228,267,269,
                     271..272,274,285)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270961"
     Site            order(166,228,230,267,269,271,288,303..306)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270961"
     Site            284..306
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270961"
     CDS             1..906
                     /gene="map3k12"
                     /coded_by="XM_026272726.1:326..3046"
                     /db_xref="GeneID:113109148"
ORIGIN      
        1 macvheqhap spslsgfstp lseppfcrpd sevpastpdt eltptqcvlr nvlsidpvgg
       61 gsgthsnspt lsdeptnfsn svlklqegga eggamrnqad sfrlqagggg fleglfgclk
      121 pvwtmigkay stehkqsqev srmslpeswe vpfeeiselq wvgsgaqgav flgkfhgeev
      181 avkkvrdvke teikhlrklk hpniitfkgv ctqapcycii meycaqgqly evlragrkim
      241 psllvdwamg iaggmnylhl hkiihrdlks pnmlithddl vkisdfgtsk elrdkstkms
      301 fagtvawmap evirnepvse kvdiwsfgvv lwemltgeip ykdvdssaii wgvgnnslql
      361 plpescpdgf killrqcwnc kprnrpsfrq illhldiasa dvlstpqety frsqaewree
      421 vkqhfekiks egtclhrlde elinrrreel rhaldirehy erklerannl ymelnavmlq
      481 lelkekellr reqcldkkyp glfkhhpstt vdklikkrnv pqklpshgkr pdllrseiil
      541 pkmdtgvlqv tvppcanrgp tspsrarrvk trhrrsgkgs sgdlsgpkhp sapasrerep
      601 plpntptptp pltetasgav mregqleppp lklsssspdl lsstrraedg vsgaaptetl
      661 ggetsagaea gagldetppr sdtasedaas lpfssspdsp ccgrsgavgr thvgeereeg
      721 tgtvrlprgs sgshltpsai lyraaitrkq rrgvsseeee gevdsevdlp rrrrptsitk
      781 cqsvstfsse nlsvsegeeg httdhshsgt pdvvstntde rlddrsddli sqgseipvdi
      841 tdptlserea aaleqeranf dleqniletr alcedsdcds aeldqsgsge psrppsaggw
      901 gqgpqn
//
LOCUS       XP_026128512             899 aa            linear   VRT 18-JUN-2025
DEFINITION  mitogen-activated protein kinase kinase kinase 12 isoform X2
            [Carassius auratus].
ACCESSION   XP_026128512
VERSION     XP_026128512.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272727.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..899
                     /product="mitogen-activated protein kinase kinase kinase
                     12 isoform X2"
                     /calculated_mol_wt=98536
     Region          155..391
                     /region_name="STKc_MAP3K12_13"
                     /note="Catalytic domain of the Serine/Threonine Kinases,
                     Mitogen-Activated Protein Kinase Kinase Kinases 12 and 13;
                     cd14059"
                     /db_xref="CDD:270961"
     Site            order(155..159,163,174,176,198,214..217,221,223,260,262,
                     264..265,267,278,281,296..299)
                     /site_type="active"
                     /db_xref="CDD:270961"
     Site            order(155..159,163,174,176,198,214..217,221,260,262,
                     264..265,267,278)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270961"
     Site            order(159,221,223,260,262,264,281,296..299)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270961"
     Site            277..299
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270961"
     CDS             1..899
                     /gene="map3k12"
                     /coded_by="XM_026272727.1:326..3025"
                     /db_xref="GeneID:113109148"
ORIGIN      
        1 macvheqhap spslsgfstp lseppfcrpd sevpastpdt eltptqcvlr nvlsidpvgg
       61 gsgthsnspt lsdeptnfsn svlklqegga eggamrnqad sfrlqagggg fleglfgclk
      121 pvwtmigkay stehkqsqee swevpfeeis elqwvgsgaq gavflgkfhg eevavkkvrd
      181 vketeikhlr klkhpniitf kgvctqapcy ciimeycaqg qlyevlragr kimpsllvdw
      241 amgiaggmny lhlhkiihrd lkspnmlith ddlvkisdfg tskelrdkst kmsfagtvaw
      301 mapevirnep vsekvdiwsf gvvlwemltg eipykdvdss aiiwgvgnns lqlplpescp
      361 dgfkillrqc wnckprnrps frqillhldi asadvlstpq etyfrsqaew reevkqhfek
      421 iksegtclhr ldeelinrrr eelrhaldir ehyerklera nnlymelnav mlqlelkeke
      481 llrreqcldk kypglfkhhp sttvdklikk rnvpqklpsh gkrpdllrse iilpkmdtgv
      541 lqvtvppcan rgptspsrar rvktrhrrsg kgssgdlsgp khpsapasre repplpntpt
      601 ptppltetas gavmregqle ppplklssss pdllsstrra edgvsgaapt etlggetsag
      661 aeagagldet pprsdtased aaslpfsssp dspccgrsga vgrthvgeer eegtgtvrlp
      721 rgssgshltp sailyraait rkqrrgvsse eeegevdsev dlprrrrpts itkcqsvstf
      781 ssenlsvseg eeghttdhsh sgtpdvvstn tderlddrsd dlisqgseip vditdptlse
      841 reaaaleqer anfdleqnil etralcedsd cdsaeldqsg sgepsrppsa ggwgqgpqn
//
LOCUS       XP_026128513             891 aa            linear   VRT 18-JUN-2025
DEFINITION  mitogen-activated protein kinase kinase kinase 12 isoform X3
            [Carassius auratus].
ACCESSION   XP_026128513
VERSION     XP_026128513.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272728.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..891
                     /product="mitogen-activated protein kinase kinase kinase
                     12 isoform X3"
                     /calculated_mol_wt=97683
     Region          162..398
                     /region_name="STKc_MAP3K12_13"
                     /note="Catalytic domain of the Serine/Threonine Kinases,
                     Mitogen-Activated Protein Kinase Kinase Kinases 12 and 13;
                     cd14059"
                     /db_xref="CDD:270961"
     Site            order(162..166,170,181,183,205,221..224,228,230,267,269,
                     271..272,274,285,288,303..306)
                     /site_type="active"
                     /db_xref="CDD:270961"
     Site            order(162..166,170,181,183,205,221..224,228,267,269,
                     271..272,274,285)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270961"
     Site            order(166,228,230,267,269,271,288,303..306)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270961"
     Site            284..306
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270961"
     CDS             1..891
                     /gene="map3k12"
                     /coded_by="XM_026272728.1:326..3001"
                     /db_xref="GeneID:113109148"
ORIGIN      
        1 macvheqhap spslsgfstp lseppfcrpd sevpastpdt eltptqcvlr nvlsidpvgg
       61 gsgthsnspt lsdeptnfsn svlklqegga eggamrnqad sfrlqagggg fleglfgclk
      121 pvwtmigkay stehkqsqev srmslpeswe vpfeeiselq wvgsgaqgav flgkfhgeev
      181 avkkvrdvke teikhlrklk hpniitfkgv ctqapcycii meycaqgqly evlragrkim
      241 psllvdwamg iaggmnylhl hkiihrdlks pnmlithddl vkisdfgtsk elrdkstkms
      301 fagtvawmap evirnepvse kvdiwsfgvv lwemltgeip ykdvdssaii wgvgnnslql
      361 plpescpdgf killrqcwnc kprnrpsfrq illhldiasa dvlstpqety frsqaewree
      421 vkqhfekiks egtclhrlde elinrrreel rhaldirehy erklerannl ymelnavmlq
      481 lelkekellr reqcldkkyp glfkhhpstt vdklikkrnv pqklpshgkr pdllrseiil
      541 pkmdtgvlqv tvppcanrgp tspsrarrvk trhrrsgkgs sgdlsgpkhp sapasrerep
      601 plpntptptp pltetasgav mregqleppp lklsssspdl lsstrraedg vsgaaptetl
      661 ggetsagaea gagldetppr sdtasedaas lpfssspdsp ccgrsgavgr thvgeereeg
      721 tgtvrlprgs sgshltpsai lyraaitrkq rrgvsseeee gevdsevdlp rrrsenlsvs
      781 egeeghttdh shsgtpdvvs tntderlddr sddlisqgse ipvditdptl sereaaaleq
      841 eranfdleqn iletralced sdcdsaeldq sgsgepsrpp saggwgqgpq n
//
LOCUS       XP_026128514             773 aa            linear   VRT 18-JUN-2025
DEFINITION  mitogen-activated protein kinase kinase kinase 12 isoform X4
            [Carassius auratus].
ACCESSION   XP_026128514
VERSION     XP_026128514.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272729.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..773
                     /product="mitogen-activated protein kinase kinase kinase
                     12 isoform X4"
                     /calculated_mol_wt=85090
     Region          162..398
                     /region_name="STKc_MAP3K12_13"
                     /note="Catalytic domain of the Serine/Threonine Kinases,
                     Mitogen-Activated Protein Kinase Kinase Kinases 12 and 13;
                     cd14059"
                     /db_xref="CDD:270961"
     Site            order(162..166,170,181,183,205,221..224,228,230,267,269,
                     271..272,274,285,288,303..306)
                     /site_type="active"
                     /db_xref="CDD:270961"
     Site            order(162..166,170,181,183,205,221..224,228,267,269,
                     271..272,274,285)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270961"
     Site            order(166,228,230,267,269,271,288,303..306)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270961"
     Site            284..306
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270961"
     CDS             1..773
                     /gene="map3k12"
                     /coded_by="XM_026272729.1:326..2647"
                     /db_xref="GeneID:113109148"
ORIGIN      
        1 macvheqhap spslsgfstp lseppfcrpd sevpastpdt eltptqcvlr nvlsidpvgg
       61 gsgthsnspt lsdeptnfsn svlklqegga eggamrnqad sfrlqagggg fleglfgclk
      121 pvwtmigkay stehkqsqev srmslpeswe vpfeeiselq wvgsgaqgav flgkfhgeev
      181 avkkvrdvke teikhlrklk hpniitfkgv ctqapcycii meycaqgqly evlragrkim
      241 psllvdwamg iaggmnylhl hkiihrdlks pnmlithddl vkisdfgtsk elrdkstkms
      301 fagtvawmap evirnepvse kvdiwsfgvv lwemltgeip ykdvdssaii wgvgnnslql
      361 plpescpdgf killrqcwnc kprnrpsfrq illhldiasa dvlstpqety frsqaewree
      421 vkqhfekiks egtclhrlde elinrrreel rhaldirehy erklerannl ymelnavmlq
      481 lelkekellr reqcldkkyp glfkhhpstt vdklikkrnv pqklpshgkr pdllrseiil
      541 pkmdtgvlqv tvppcanrgp tspsrarrvk trhrrsgkgs sgdlsgpkhp sapasrerep
      601 plpntptptp pltetasgav mregqleppp lklsssspdl lsstrraedg vsgaaptetl
      661 ggetsagaea gagldetppr sdtasedaas lpfssspdsp ccgrsgavgr thvgeereeg
      721 tgtvrlprgs sgshltpsai lyraaitrkq rrgvsseeee gevdsevdlp rrr
//
LOCUS       XP_026128515             373 aa            linear   VRT 18-JUN-2025
DEFINITION  poly(rC)-binding protein 2 isoform X1 [Carassius auratus].
ACCESSION   XP_026128515
VERSION     XP_026128515.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272730.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..373
                     /product="poly(rC)-binding protein 2 isoform X1"
                     /calculated_mol_wt=38997
     Region          13..82
                     /region_name="KH-I_PCBP1_2_rpt1"
                     /note="first type I K homology (KH) RNA-binding domain
                     found in poly(rC)-binding protein 1 (PCBP1) and similar
                     proteins; cd22515"
                     /db_xref="CDD:411943"
     Site            order(22,26..27,29..33,36,40,48..51,53,57)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411943"
     Region          93..171
                     /region_name="KH-I"
                     /note="K homology (KH) RNA-binding domain, type I;
                     cl00098"
                     /db_xref="CDD:469614"
     Region          292..367
                     /region_name="KH-I_PCBP1_2_rpt3"
                     /note="third type I K homology (KH) RNA-binding domain
                     found in poly(rC)-binding protein 1 (PCBP1) and similar
                     proteins; cd22521"
                     /db_xref="CDD:411949"
     Site            order(305..309,311..315,317..319,322,330..331,333,341,366)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411949"
     CDS             1..373
                     /gene="LOC113109149"
                     /coded_by="XM_026272730.1:239..1360"
                     /db_xref="GeneID:113109149"
ORIGIN      
        1 mdsgvieggl nvtltirllm hgkevgsiig kkgesvkkmr eesgarinis egncperiit
       61 lagpttaifk afsmiiekle edisssmsns tatskppvtl rivvpasqcg sligkggcki
      121 keirestgaq vqvagdmlpn steraitiag tplsiiecvk qicvvmlesp pkgvtipyrp
      181 kpsgspvifa ggqvsvsvpp aavvcvcvce rkicvssqtc vlqayavqgq haipqpdltk
      241 lhqlamqqsp fplapssqgf tgrslsqtll lcvcschwli vflcsaagmd ataqtgshel
      301 tipndligci igrqgakine irqmsgaqik ianpvegstd rqvtitgspa sislaeylin
      361 arlsseatgm aan
//
LOCUS       XP_026128516             348 aa            linear   VRT 18-JUN-2025
DEFINITION  poly(rC)-binding protein 2 isoform X2 [Carassius auratus].
ACCESSION   XP_026128516
VERSION     XP_026128516.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272731.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..348
                     /product="poly(rC)-binding protein 2 isoform X2"
                     /calculated_mol_wt=36261
     Region          13..82
                     /region_name="KH-I_PCBP1_2_rpt1"
                     /note="first type I K homology (KH) RNA-binding domain
                     found in poly(rC)-binding protein 1 (PCBP1) and similar
                     proteins; cd22515"
                     /db_xref="CDD:411943"
     Site            order(22,26..27,29..33,36,40,48..51,53,57)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411943"
     Region          93..171
                     /region_name="KH-I"
                     /note="K homology (KH) RNA-binding domain, type I;
                     cl00098"
                     /db_xref="CDD:469614"
     Region          267..342
                     /region_name="KH-I_PCBP1_2_rpt3"
                     /note="third type I K homology (KH) RNA-binding domain
                     found in poly(rC)-binding protein 1 (PCBP1) and similar
                     proteins; cd22521"
                     /db_xref="CDD:411949"
     Site            order(280..284,286..290,292..294,297,305..306,308,316,341)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411949"
     CDS             1..348
                     /gene="LOC113109149"
                     /coded_by="XM_026272731.1:239..1285"
                     /db_xref="GeneID:113109149"
ORIGIN      
        1 mdsgvieggl nvtltirllm hgkevgsiig kkgesvkkmr eesgarinis egncperiit
       61 lagpttaifk afsmiiekle edisssmsns tatskppvtl rivvpasqcg sligkggcki
      121 keirestgaq vqvagdmlpn steraitiag tplsiiecvk qicvvmlesp pkgvtipyrp
      181 kpsgspvifa ggqvsvsvpp aavvcvcvce rkicvssqtc vlqayavqgq haipqpdltk
      241 lhqlamqqsp fplapssqgf tagmdataqt gsheltipnd ligciigrqg akineirqms
      301 gaqikianpv egstdrqvti tgspasisla eylinarlss eatgmaan
//
LOCUS       XP_026128517             343 aa            linear   VRT 18-JUN-2025
DEFINITION  poly(rC)-binding protein 2 isoform X3 [Carassius auratus].
ACCESSION   XP_026128517
VERSION     XP_026128517.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272732.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..343
                     /product="poly(rC)-binding protein 2 isoform X3"
                     /calculated_mol_wt=35907
     Region          13..82
                     /region_name="KH-I_PCBP1_2_rpt1"
                     /note="first type I K homology (KH) RNA-binding domain
                     found in poly(rC)-binding protein 1 (PCBP1) and similar
                     proteins; cd22515"
                     /db_xref="CDD:411943"
     Site            order(22,26..27,29..33,36,40,48..51,53,57)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411943"
     Region          93..171
                     /region_name="KH-I"
                     /note="K homology (KH) RNA-binding domain, type I;
                     cl00098"
                     /db_xref="CDD:469614"
     Region          262..337
                     /region_name="KH-I_PCBP1_2_rpt3"
                     /note="third type I K homology (KH) RNA-binding domain
                     found in poly(rC)-binding protein 1 (PCBP1) and similar
                     proteins; cd22521"
                     /db_xref="CDD:411949"
     Site            order(275..279,281..285,287..289,292,300..301,303,311,336)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411949"
     CDS             1..343
                     /gene="LOC113109149"
                     /coded_by="XM_026272732.1:239..1270"
                     /db_xref="GeneID:113109149"
ORIGIN      
        1 mdsgvieggl nvtltirllm hgkevgsiig kkgesvkkmr eesgarinis egncperiit
       61 lagpttaifk afsmiiekle edisssmsns tatskppvtl rivvpasqcg sligkggcki
      121 keirestgaq vqvagdmlpn steraitiag tplsiiecvk qicvvmlesp pkgvtipyrp
      181 kpsgspvifa ggqayavqgq haipqpdltk lhqlamqqsp fplapssqgf tgrslsqtll
      241 lcvcschwli vflcsaagmd ataqtgshel tipndligci igrqgakine irqmsgaqik
      301 ianpvegstd rqvtitgspa sislaeylin arlsseatgm aan
//
LOCUS       XP_026128518             318 aa            linear   VRT 18-JUN-2025
DEFINITION  poly(rC)-binding protein 2 isoform X4 [Carassius auratus].
ACCESSION   XP_026128518
VERSION     XP_026128518.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272733.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..318
                     /product="poly(rC)-binding protein 2 isoform X4"
                     /calculated_mol_wt=33171
     Region          13..82
                     /region_name="KH-I_PCBP1_2_rpt1"
                     /note="first type I K homology (KH) RNA-binding domain
                     found in poly(rC)-binding protein 1 (PCBP1) and similar
                     proteins; cd22515"
                     /db_xref="CDD:411943"
     Site            order(22,26..27,29..33,36,40,48..51,53,57)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411943"
     Region          93..171
                     /region_name="KH-I"
                     /note="K homology (KH) RNA-binding domain, type I;
                     cl00098"
                     /db_xref="CDD:469614"
     Region          237..312
                     /region_name="KH-I_PCBP1_2_rpt3"
                     /note="third type I K homology (KH) RNA-binding domain
                     found in poly(rC)-binding protein 1 (PCBP1) and similar
                     proteins; cd22521"
                     /db_xref="CDD:411949"
     Site            order(250..254,256..260,262..264,267,275..276,278,286,311)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:411949"
     CDS             1..318
                     /gene="LOC113109149"
                     /coded_by="XM_026272733.1:238..1194"
                     /db_xref="GeneID:113109149"
ORIGIN      
        1 mdsgvieggl nvtltirllm hgkevgsiig kkgesvkkmr eesgarinis egncperiit
       61 lagpttaifk afsmiiekle edisssmsns tatskppvtl rivvpasqcg sligkggcki
      121 keirestgaq vqvagdmlpn steraitiag tplsiiecvk qicvvmlesp pkgvtipyrp
      181 kpsgspvifa ggqayavqgq haipqpdltk lhqlamqqsp fplapssqgf tagmdataqt
      241 gsheltipnd ligciigrqg akineirqms gaqikianpv egstdrqvti tgspasisla
      301 eylinarlss eatgmaan
//
LOCUS       XP_026128519             599 aa            linear   VRT 18-JUN-2025
DEFINITION  activin receptor type-1 isoform X1 [Carassius auratus].
ACCESSION   XP_026128519
VERSION     XP_026128519.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272734.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..599
                     /product="activin receptor type-1 isoform X1"
                     /calculated_mol_wt=66445
     Region          40..109
                     /region_name="TFP_LU_ECD_ALK2"
                     /note="extracellular domain (ECD) found in activin
                     receptor-like kinase 2 (ALK-2) and similar proteins;
                     cd23535"
                     /db_xref="CDD:467065"
     Region          127..197
                     /region_name="TFP_LU_ECD_ALK2"
                     /note="extracellular domain (ECD) found in activin
                     receptor-like kinase 2 (ALK-2) and similar proteins;
                     cd23535"
                     /db_xref="CDD:467065"
     Region          271..298
                     /region_name="TGF_beta_GS"
                     /note="Transforming growth factor beta type I GS-motif;
                     pfam08515"
                     /db_xref="CDD:462503"
     Region          294..589
                     /region_name="STKc_ACVR1_ALK1"
                     /note="Catalytic domain of the Serine/Threonine Kinases,
                     Activin Type I Receptor and Activin receptor-Like Kinase
                     1; cd14142"
                     /db_xref="CDD:271044"
     Site            order(294..295,298..299,337..338,341..342,345..346,360,
                     362)
                     /site_type="other"
                     /note="FKBP12 binding site [polypeptide binding]"
                     /db_xref="CDD:271044"
     Site            order(306..310,314,325,327,355,375..378,382,384,428,430,
                     432..433,435,446,449,469..472)
                     /site_type="active"
                     /db_xref="CDD:271044"
     Site            order(306..312,314,325,327,375..376,378,382,432..433,435,
                     446)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271044"
     Site            order(310,382,384,428,430,432,449,469..472)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271044"
     Site            445..472
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271044"
     CDS             1..599
                     /gene="LOC113109150"
                     /coded_by="XM_026272734.1:248..2047"
                     /db_xref="GeneID:113109150"
ORIGIN      
        1 mmpiffrpvm lsskmflllt vmlvspagcm kdkgstgdve cvceglscdd vqhclglqcf
       61 sslssengta fqqkgcivgs eevamrckns qtvdmlmhcc ketlcnmnvt lempstdeel
      121 rvaptehecv cegrscaagd rckgqqcfss ltlsdgtpvs qkgcfkvyeq grmtcktpps
      181 pdqiveccqa hlcnmnltvr lpvrvvegpn ysvttltivi vapvfvlifl sgvailifrc
      241 ihhhqmehlt ahdaeygpid gliasnvges tladlldhsc tsgsgsglpf lvqrtvarqi
      301 tlsecvgkgr ygevwrgqwq gesvavkifs srdekswfre teiyntvllr hdnilgfias
      361 dmtsrnsstq lwlithfhem gslydylqls mldasaclrm alsiasglah lhveifgtqg
      421 kpaiahrdlk sknilvnkng qcciadlgla vmhfqdtnel dvgnnpkvgt krymapevld
      481 dsiqtdcfes ykrvdiwafg lvlweiarrt vsngivedyk ppfhdvvpsd psfedmkkvi
      541 cidqqrpnip nrwfsdptlt sivklmkecw yqnpsarlta lrikktltkn sldkikadi
//
LOCUS       XP_026128520             514 aa            linear   VRT 18-JUN-2025
DEFINITION  activin receptor type-1 isoform X2 [Carassius auratus].
ACCESSION   XP_026128520
VERSION     XP_026128520.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272735.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..514
                     /product="activin receptor type-1 isoform X2"
                     /calculated_mol_wt=57316
     Region          42..112
                     /region_name="TFP_LU_ECD_ALK2"
                     /note="extracellular domain (ECD) found in activin
                     receptor-like kinase 2 (ALK-2) and similar proteins;
                     cd23535"
                     /db_xref="CDD:467065"
     Region          186..213
                     /region_name="TGF_beta_GS"
                     /note="Transforming growth factor beta type I GS-motif;
                     pfam08515"
                     /db_xref="CDD:462503"
     Region          209..504
                     /region_name="STKc_ACVR1_ALK1"
                     /note="Catalytic domain of the Serine/Threonine Kinases,
                     Activin Type I Receptor and Activin receptor-Like Kinase
                     1; cd14142"
                     /db_xref="CDD:271044"
     Site            order(209..210,213..214,252..253,256..257,260..261,275,
                     277)
                     /site_type="other"
                     /note="FKBP12 binding site [polypeptide binding]"
                     /db_xref="CDD:271044"
     Site            order(221..225,229,240,242,270,290..293,297,299,343,345,
                     347..348,350,361,364,384..387)
                     /site_type="active"
                     /db_xref="CDD:271044"
     Site            order(221..227,229,240,242,290..291,293,297,347..348,350,
                     361)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271044"
     Site            order(225,297,299,343,345,347,364,384..387)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271044"
     Site            360..387
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271044"
     CDS             1..514
                     /gene="LOC113109150"
                     /coded_by="XM_026272735.1:248..1792"
                     /db_xref="GeneID:113109150"
ORIGIN      
        1 mmpiffrpvm lsskmflllt vmlvspagcm kdeelrvapt ehecvcegrs caagdrckgq
       61 qcfssltlsd gtpvsqkgcf kvyeqgrmtc ktppspdqiv eccqahlcnm nltvrlpvrv
      121 vegpnysvtt ltivivapvf vliflsgvai lifrcihhhq mehltahdae ygpidglias
      181 nvgestladl ldhsctsgsg sglpflvqrt varqitlsec vgkgrygevw rgqwqgesva
      241 vkifssrdek swfreteiyn tvllrhdnil gfiasdmtsr nsstqlwlit hfhemgslyd
      301 ylqlsmldas aclrmalsia sglahlhvei fgtqgkpaia hrdlksknil vnkngqccia
      361 dlglavmhfq dtneldvgnn pkvgtkryma pevlddsiqt dcfesykrvd iwafglvlwe
      421 iarrtvsngi vedykppfhd vvpsdpsfed mkkvicidqq rpnipnrwfs dptltsivkl
      481 mkecwyqnps arltalrikk tltknsldki kadi
//
LOCUS       XP_026128521             492 aa            linear   VRT 18-JUN-2025
DEFINITION  activin receptor type-1C isoform X1 [Carassius auratus].
ACCESSION   XP_026128521
VERSION     XP_026128521.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272736.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..492
                     /product="activin receptor type-1C isoform X1"
                     /calculated_mol_wt=55282
     Region          22..97
                     /region_name="TFP"
                     /note="three-fingered protein (TFP) fold found in Ly6/uPAR
                     (LU) and snake toxin superfamily; cl45932"
                     /db_xref="CDD:480272"
     Region          166..192
                     /region_name="TGF_beta_GS"
                     /note="Transforming growth factor beta type I GS-motif;
                     pfam08515"
                     /db_xref="CDD:462503"
     Region          198..484
                     /region_name="STKc_TGFbR1_ACVR1b_ACVR1c"
                     /note="Catalytic domain of the Serine/Threonine Kinases,
                     Transforming Growth Factor beta Type I Receptor and
                     Activin Type IB/IC Receptors; cd14143"
                     /db_xref="CDD:271045"
     Site            order(200..204,208,219,221,249,269..272,276,278,322,324,
                     326..327,329,340,343,363..366)
                     /site_type="active"
                     /db_xref="CDD:271045"
     Site            order(200..206,208,219,221,269..270,272,276,326..327,329,
                     340)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271045"
     Site            order(204,276,278,322,324,326,343,363..366)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271045"
     Site            order(231..232,235..236,239..240,254,256)
                     /site_type="other"
                     /note="FKBP12 binding site [polypeptide binding]"
                     /db_xref="CDD:271045"
     Site            339..366
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271045"
     CDS             1..492
                     /gene="acvr1c"
                     /coded_by="XM_026272736.1:18..1496"
                     /db_xref="GeneID:113109151"
ORIGIN      
        1 mflacnlfiy fcqisicssf fsalkcvcpl cvnhtcetea egacwnsvml ingkeevvks
       61 clspselkgq vfcyssryvs krnccftdfc nnetlhlnpe pppegsgwsq lelaavilvp
      121 sclvcvgvil gkcaiqnlrc nhikahkqdp eeplddqtlv spdkclkeli ydmssfgsgs
      181 glpllvqrti artivlqesi gkgrfgevwr gkwrgedvav kifstrders wfreaeiyqt
      241 imlrhenilg fiaadnkdng swtqlwlvse yhehgslfdy lnrytvsveg mivlalsias
      301 giahlhmeii gtqgkpaiah rdiksknilv kkngtaviad lglavkhdsn tntvdipinh
      361 rvgtkrymap eilddsints sfesfkradi yslglvfwel arrcsvqgiy edfqlpyydq
      421 vqsdpsvddm rkvvceqklr pnipnqwqsc ealrvmgkim recwyaspaa rltalrvkkt
      481 vpqvtvvkdi ke
//
LOCUS       XP_026128522             491 aa            linear   VRT 18-JUN-2025
DEFINITION  activin receptor type-1C isoform X2 [Carassius auratus].
ACCESSION   XP_026128522
VERSION     XP_026128522.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272737.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..491
                     /product="activin receptor type-1C isoform X2"
                     /calculated_mol_wt=55089
     Region          22..96
                     /region_name="TFP"
                     /note="three-fingered protein (TFP) fold found in Ly6/uPAR
                     (LU) and snake toxin superfamily; cl45932"
                     /db_xref="CDD:480272"
     Region          165..191
                     /region_name="TGF_beta_GS"
                     /note="Transforming growth factor beta type I GS-motif;
                     pfam08515"
                     /db_xref="CDD:462503"
     Region          197..483
                     /region_name="STKc_TGFbR1_ACVR1b_ACVR1c"
                     /note="Catalytic domain of the Serine/Threonine Kinases,
                     Transforming Growth Factor beta Type I Receptor and
                     Activin Type IB/IC Receptors; cd14143"
                     /db_xref="CDD:271045"
     Site            order(199..203,207,218,220,248,268..271,275,277,321,323,
                     325..326,328,339,342,362..365)
                     /site_type="active"
                     /db_xref="CDD:271045"
     Site            order(199..205,207,218,220,268..269,271,275,325..326,328,
                     339)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271045"
     Site            order(203,275,277,321,323,325,342,362..365)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271045"
     Site            order(230..231,234..235,238..239,253,255)
                     /site_type="other"
                     /note="FKBP12 binding site [polypeptide binding]"
                     /db_xref="CDD:271045"
     Site            338..365
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271045"
     CDS             1..491
                     /gene="acvr1c"
                     /coded_by="XM_026272737.1:95..1570"
                     /db_xref="GeneID:113109151"
ORIGIN      
        1 msylrcteaa lllftfvqlt aalkcvcplc vnhtceteae gacwnsvmli ngkeevvksc
       61 lspselkgqv fcyssryvsk rnccftdfcn netlhlnpep ppegsgwsql elaavilvps
      121 clvcvgvilg kcaiqnlrcn hikahkqdpe eplddqtlvs pdkclkeliy dmssfgsgsg
      181 lpllvqrtia rtivlqesig kgrfgevwrg kwrgedvavk ifstrdersw freaeiyqti
      241 mlrhenilgf iaadnkdngs wtqlwlvsey hehgslfdyl nrytvsvegm ivlalsiasg
      301 iahlhmeiig tqgkpaiahr diksknilvk kngtaviadl glavkhdsnt ntvdipinhr
      361 vgtkrymape ilddsintss fesfkradiy slglvfwela rrcsvqgiye dfqlpyydqv
      421 qsdpsvddmr kvvceqklrp nipnqwqsce alrvmgkimr ecwyaspaar ltalrvkktv
      481 pqvtvvkdik e
//
LOCUS       XP_026128523             342 aa            linear   VRT 18-JUN-2025
DEFINITION  cytohesin-interacting protein-like [Carassius auratus].
ACCESSION   XP_026128523
VERSION     XP_026128523.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272738.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..342
                     /product="cytohesin-interacting protein-like"
                     /calculated_mol_wt=38057
     Region          73..163
                     /region_name="PDZ_tamalin_CYTIP-like"
                     /note="PDZ domain of tamalin, cytohesin-1-interacting
                     protein (CYTIP), and related domains; cd06713"
                     /db_xref="CDD:467197"
     Site            order(87..93,112,115,144,148,151..152)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467197"
     CDS             1..342
                     /gene="LOC113109153"
                     /coded_by="XM_026272738.1:83..1111"
                     /db_xref="GeneID:113109153"
ORIGIN      
        1 mtsnknfkap lkqlssldsy iiensqkkkn ilwrrcsfns tknsnteeir dgtlsrrklh
       61 rtysaslvdy tdpqrtmvil ekqdneafgf evqtyglkvk nssivemctf vcsvqdgsaa
      121 etagltagdi ilsvngvsie gsthqhiiel irestnmlkl etvsgnvvkr ielekkmryl
      181 kqtlrekwve lqsltlqekr ltrgnlnesa qhlsvdslls lssptgrsgh rfssdsscrs
      241 imtddsedaa fmssvfdvss pisptepneg ffrleggalr pltrtrsisl tssnsslsps
      301 wenssssmfg tlprrgrkss vrkhilkfip glnhsveeee gs
//
LOCUS       XP_026128524             825 aa            linear   VRT 18-JUN-2025
DEFINITION  polypeptide N-acetylgalactosaminyltransferase 5 [Carassius
            auratus].
ACCESSION   XP_026128524
VERSION     XP_026128524.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272739.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..825
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..825
                     /product="polypeptide N-acetylgalactosaminyltransferase 5"
                     /calculated_mol_wt=94938
     Region          388..691
                     /region_name="pp-GalNAc-T"
                     /note="pp-GalNAc-T initiates the formation of mucin-type
                     O-linked glycans; cd02510"
                     /db_xref="CDD:133004"
     Site            order(392..394,396,425,454,457,461,477..479,561..562,
                     584..585,587,612,615,620)
                     /site_type="active"
                     /note="ligand binding site [active]"
                     /db_xref="CDD:133004"
     Site            order(477,479,612)
                     /site_type="active"
                     /note="Mn binding site [active]"
                     /db_xref="CDD:133004"
     Region          697..823
                     /region_name="beta-trefoil_Ricin-like"
                     /note="ricin B-type lectin domain, beta-trefoil fold;
                     cl49609"
                     /db_xref="CDD:483949"
     Site            order(715..717,722,724,732..733)
                     /site_type="other"
                     /note="sugar binding site [chemical binding]"
                     /db_xref="CDD:467293"
     Site            order(751..752,758,760,768..769)
                     /site_type="other"
                     /note="sugar binding site [chemical binding]"
                     /db_xref="CDD:467293"
     Site            order(795..797,804,806,814..815)
                     /site_type="other"
                     /note="sugar binding site [chemical binding]"
                     /db_xref="CDD:467293"
     CDS             1..825
                     /gene="galnt5"
                     /coded_by="XM_026272739.1:886..3363"
                     /db_xref="GeneID:113109154"
ORIGIN      
        1 mkfrkylrgs grvlafvfia sviwllfdia alrisfisdl npdlkqreie lkqgrrkdnv
       61 kdvlkqplqn vnidkkeflk nsnrferkvd kvyrkrpmar ptnqvelkqd krlnpmsmad
      121 ksfvkqnevi nqskvnlivn slakgtiisi pekinktktv invkvknitt kinkikaafn
      181 eqadanldik ahiltkalpt vqekmhppaf kedsvkkvhn ingtvvmpnn evhvdaglqr
      241 nlsnellkpa dgdkpkniie nsekhgntfn ktkpdiiqkp selkdqnpae eanrvphsts
      301 vqvrrsgghh kvmaldvtdr prdpravgqf gqparvprdk elesrrrwse gffnvflseq
      361 ipldraipdt rpqicseniv hddlpstsvi fcfvdevwst llrsvhsvln rspphllkei
      421 ilvddcsskd ylkeqldvym sqfpkvriir lkerqglira riagaasatg evltfldshv
      481 ecnvgwlepl lervyldrkk vvcpvievis dkdmsymlvd nfqrgifrwp lvfgwsalpe
      541 eyirknqikd sdpircpvma gglfsidksy fyelgaydpg ldvwggenme isfkiwmcgg
      601 eieiipcsrv ghifrgdnpy kfpkdrvktv ernlarvaev wlddykelfy ghgyhhlldk
      661 rvtdignlte qielrkklqc ksfkwylenv ypdldaplvk aeglifnvgt rkclvfekdi
      721 lffdkcdltn ksqhfsytwl rmvrqntscl apqekeiime pcdstkphlr wmhksgkglt
      781 ehvmmeghsq picleagvka dsiflkdcdt vntfqkwqft hyyae
//
LOCUS       XP_026128525             599 aa            linear   VRT 18-JUN-2025
DEFINITION  nuclear receptor subfamily 4 group A member 2a [Carassius auratus].
ACCESSION   XP_026128525
VERSION     XP_026128525.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272740.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..599
                     /product="nuclear receptor subfamily 4 group A member 2a"
                     /calculated_mol_wt=66684
     Region          262..336
                     /region_name="NR_DBD_NGFI-B"
                     /note="DNA-binding domain of the orphan nuclear receptor,
                     nerve growth factor-induced-B; cd06969"
                     /db_xref="CDD:143527"
     Site            order(264,267,281,284,300,306,316,319)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:143527"
     Site            order(273..276,282..283,285,287,289..290,313..314,317,320,
                     333..335)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143527"
     Region          368..599
                     /region_name="NR_LBD_Nurr1"
                     /note="The ligand binding domain of Nurr1, a member of
                     conserved family of nuclear receptors; cd07071"
                     /db_xref="CDD:132756"
     Site            order(371,374,377,500)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:132756"
     Site            order(416,419,423,428,433..434,436..437,440..441,588,591,
                     595)
                     /site_type="active"
                     /note="putative coactivator recognition site [active]"
                     /db_xref="CDD:132756"
     CDS             1..599
                     /gene="nr4a2a"
                     /coded_by="XM_026272740.1:215..2014"
                     /db_xref="GeneID:113109155"
ORIGIN      
        1 mpcvqaqygs spqgaspasq sysyhtsgey scdfltpefv kfsmdltnte itaattslps
       61 fstfmdnynt gydvkppcly qvphsgeqss ikveevqmht yhqqshlgpq seemmahsgp
      121 myfkpsspha pgaanfqvqp nhmwedpssl htfhqnymtt hmidqrknpv srlslfsfkq
      181 sppgtpvssc qmrfdgplhv smghdssgah raldsqsfam psairkqagi afthslqlsh
      241 ghqlmdsqmp sppsrgspss eglcavcgdn aacqhygvrt cegckgffkr tvqknakyvc
      301 lankncpvdk rrrnrcqycr fqkclvvgmv kevvrtanlk grrgrlpskp kspqesspps
      361 ppvslisalv rahvdsnpsm ssldytrfqa npdyqlsgdd tqhiqqfydl ltgsmeiirg
      421 waekipgftd lpkpdqdllf esaflelfvl rlayrsnpme gklifcngvv lhrlqcvrgf
      481 gewidsiaef ssnlqnmnld isafsciaal amvterhglk epkrvedlqn kivnclkdqv
      541 tfnggglnrp nylskllgkl pelrtlctqg lqrifylkle dlvpppaiid klfldtlpf
//
LOCUS       XP_026128527             490 aa            linear   VRT 18-JUN-2025
DEFINITION  G protein-activated inward rectifier potassium channel 1 [Carassius
            auratus].
ACCESSION   XP_026128527
VERSION     XP_026128527.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272742.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..490
                     /product="G protein-activated inward rectifier potassium
                     channel 1"
                     /calculated_mol_wt=55403
     Region          34..174
                     /region_name="IRK"
                     /note="Inward rectifier potassium channel transmembrane
                     domain; pfam01007"
                     /db_xref="CDD:460023"
     Region          181..350
                     /region_name="IRK_C"
                     /note="Inward rectifier potassium channel C-terminal
                     domain; pfam17655"
                     /db_xref="CDD:465439"
     CDS             1..490
                     /gene="kcnj3a"
                     /coded_by="XM_026272742.1:706..2178"
                     /db_xref="GeneID:113109156"
ORIGIN      
        1 msalhkkfgs dyqvvtttss shqkdkrrkr qrfvdkngrc nvqhgnlgge tsrylsdlft
       61 tlvdlkwrwn lfifiltytv awlfmasmww viayirgdly rthdekytpc vanvynfpsa
      121 flffieteat igyghryitd kcpegiilfl fqsilgsivd afligcmfik msqpkkraet
      181 lmfsenaais mrdgkltlmf rvgnlrnshm vsaqirckll ksrqtpegef lpldqleldv
      241 gfstgadqlf lvspltichv idtkspfyel sqrsmqteqf eivvilegiv ettgmtcqar
      301 tsytedevlw ghrffpvisl eegffkvdys qfhatfevpt ppysakeqde allmssplma
      361 pslcnsgekn ssldclelle dpesttklpa kvqkmtgrdg lprkllrmss ttsemtyslg
      421 elpmklqris svpgvseekq vskttkiate aisksvadlp pklqrlaggg grmdghlppk
      481 lrkmnsdrft
//
LOCUS       XP_026128528             556 aa            linear   VRT 18-JUN-2025
DEFINITION  polypeptide N-acetylgalactosaminyltransferase 13 [Carassius
            auratus].
ACCESSION   XP_026128528
VERSION     XP_026128528.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272743.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..556
                     /product="polypeptide N-acetylgalactosaminyltransferase
                     13"
                     /calculated_mol_wt=63815
     Region          118..418
                     /region_name="pp-GalNAc-T"
                     /note="pp-GalNAc-T initiates the formation of mucin-type
                     O-linked glycans; cd02510"
                     /db_xref="CDD:133004"
     Site            order(122..124,126,155,185,188,192,208..210,292..293,
                     315..316,318,343,346,351)
                     /site_type="active"
                     /note="ligand binding site [active]"
                     /db_xref="CDD:133004"
     Site            order(208,210,343)
                     /site_type="active"
                     /note="Mn binding site [active]"
                     /db_xref="CDD:133004"
     Region          425..551
                     /region_name="beta-trefoil_Ricin_GALNT13"
                     /note="ricin B-type lectin domain, beta-trefoil fold,
                     found in polypeptide N-acetylgalactosaminyltransferase 13
                     (GALNT13) and similar proteins; cd23467"
                     /db_xref="CDD:467345"
     Site            order(443..446,454,456,459,464..465)
                     /site_type="other"
                     /note="putative sugar binding site [chemical binding]"
                     /db_xref="CDD:467345"
     Site            order(483..486,492,494,497,502..503)
                     /site_type="other"
                     /note="putative sugar binding site [chemical binding]"
                     /db_xref="CDD:467345"
     Site            order(524..527,535,537,540,544..545)
                     /site_type="other"
                     /note="putative sugar binding site [chemical binding]"
                     /db_xref="CDD:467345"
     CDS             1..556
                     /gene="galnt13"
                     /coded_by="XM_026272743.1:540..2210"
                     /db_xref="GeneID:113109157"
ORIGIN      
        1 mrrfvyckvv lttslvwvlv dvflllyfse cnkcdnkkdh sllpalravm srtheapgem
       61 gkavvipkde qekmkelfki nqfnlmasdm ialnrslpdv rldgcktkty pddlpntsiv
      121 ivfhneawst llrtihsain rsprhlllei llvddaserd flqkklvdhv gtlevpvril
      181 rmeqrsglir arlrgaaatr gqvitfldah cectvgwlep llarikedrr avvcpiidvi
      241 sdetfeymag sdmtyggfnw klnfrwypvp qremdrrkgd rtlpvrtptm agglfsidrt
      301 yfeeigtyds gmdiwggenl emsfriwqcg gsleivtcsh vghvfrkatp ysfpggtgqv
      361 inknnrrlae vwmdefkdff yiispgvvrv dygdvssrka lreslkckpf swyleniypd
      421 sqiprryysl geirnvetnq cvdnmgrken ekvgffnchg mggnqvfsyt adkeirtddl
      481 cldasrlngp vvmlkchhmk gnqmfeydae rltllhvnsn qcldmpseed kmvptlrdcs
      541 grrsqqwilr nmtlsv
//
LOCUS       XP_026128529             878 aa            linear   VRT 18-JUN-2025
DEFINITION  pre-mRNA-processing factor 40 homolog A-like [Carassius auratus].
ACCESSION   XP_026128529
VERSION     XP_026128529.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272744.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..878
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..878
                     /product="pre-mRNA-processing factor 40 homolog A-like"
                     /calculated_mol_wt=100130
     Region          <3..>133
                     /region_name="GGN"
                     /note="Gametogenetin; pfam15685"
                     /db_xref="CDD:434857"
     Region          137..>602
                     /region_name="PRP40"
                     /note="Splicing factor [RNA processing and modification];
                     COG5104"
                     /db_xref="CDD:227435"
     Region          665..719
                     /region_name="FF"
                     /note="Contains two conserved F residues; smart00441"
                     /db_xref="CDD:128718"
     CDS             1..878
                     /gene="LOC113109158"
                     /coded_by="XM_026272744.1:87..2723"
                     /db_xref="GeneID:113109158"
ORIGIN      
        1 mswtdansgp sqappfagvt lppsgiplpf mgppgipphf ppmgmppmgq rppsmapmpp
       61 gilppmippm gappmaqmpa mlppmipgmm mpprlpaasi qptgppgvsp vesaapaapg
      121 tasttstesd eqpkkksvwt ehksldgkty yyntetkqst wekpdelksp aeqmlskclw
      181 keyksdngkp yyynsqtkes rwtkpkeled leamikaeen gtadvvapgt ipaltsqses
      241 svtvaavaet eatmatvate eqpshvpapv advssdvtvn stedtpsvet qpsndvskee
      301 rpelvkkvyk wntkeeakqa fkellkekgv ssnasweqam kliindprys alpklsekkq
      361 afnaykvqte keekeearik ykesketfqr flenhekmts ttrykkaeqm fgdqdvwscv
      421 perdrleiye dvlfylakke keqakqlrkr nwealknild nmanvtyrtt wseaqqylld
      481 nptfaedeel qnmdkedali cfeehirale keeeeekqkt llrerrrqrk nresfqkfld
      541 elhdhgqlhs msawmemypt vsadirfnnm lgqpgstpld lfkfyvedlk aryhdekrii
      601 kdilkdkgll veintgfeef gsvissdkra ttldagnikl afnsllekae arererekee
      661 arkmkrkeaa fksmlkqatp plepeatweg trerflkepa feditleser krifkdfmhv
      721 lehecqhhhs ktkkhskksk khhrkrsrsr sgseseedey qskkkkrsas kspsehsssg
      781 esersykksk khkkkgkkrr hksgspeseg ekerkgreke kdkendksrg ktrgeskqks
      841 pkrkstkeeg gwdtsgsels egelekrrrt lleqldap
//
LOCUS       XP_026128530            1075 aa            linear   VRT 18-JUN-2025
DEFINITION  formin-like protein 2 isoform X1 [Carassius auratus].
ACCESSION   XP_026128530
VERSION     XP_026128530.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272745.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1075
                     /product="formin-like protein 2 isoform X1"
                     /calculated_mol_wt=122586
     Region          22..275
                     /region_name="Drf_GBD"
                     /note="Diaphanous GTPase-binding Domain; pfam06371"
                     /db_xref="CDD:461886"
     Region          278..475
                     /region_name="Drf_FH3"
                     /note="Diaphanous FH3 Domain; pfam06367"
                     /db_xref="CDD:461885"
     Region          599..950
                     /region_name="FH2"
                     /note="Formin Homology 2 Domain; pfam02181"
                     /db_xref="CDD:396655"
     CDS             1..1075
                     /gene="LOC113109159"
                     /coded_by="XM_026272745.1:1..3228"
                     /db_xref="GeneID:113109159"
ORIGIN      
        1 mgnagslnqh tdprghhmpl klpmpepael edrfalvlns mnlppdkarl lrqydnekkw
       61 elicdqerfq vknpphtyih klqgyldpav trkkfrrrvq estqvlrele islrtnhigw
      121 vreflneenk gldvlveyls faqyavtydg dssesstens vdkskpwnrs iedlhggnhl
      181 ssavtgssis rasrhstirs ntlpsrrtlk nsrlvckkdd lhvcimclra imnyqygfnm
      241 vmshphavne ialslnnknp rtkalvlell aavclvrggh eiilsafdhf kevcledqrf
      301 eklmehfkne dnnidfmvac mqfinivvhs vedmnfrvhl qydftklgld eyldklkhte
      361 sdklhvqiqa yldnvfdvga lledaetkna alerveelee nmshlteklq dteneamaki
      421 velekqlmqk nkeldsvrev ykdassqvht lrrmvkekde aiqkqsnlek kihelekqgt
      481 ikiqkkadgd iailtpppqg nghlpgsqgv aggsregaaq gltvpdpppp pppppmpetl
      541 pngpsapppp pplpavdisa pmppppppma pplpgcgspt vimnsglaeg piklcsvkik
      601 kpiktkfrmp vfnwvalkpn qingtvfnei dderiledln vdefeemfkt kaqgpaidit
      661 sskqktsqkg pckvslldsn raknlaitlr kvgktseeic raiqmfdlrt lpvdfveclm
      721 rfvpteaelk vlrqyekerk plenltdedr fmihfskier lmqkmtimaf vgnftesvqm
      781 ltpqlhavia asvsikssqk lkkileiila lgnymnsskr gavygfklqs ldllldtkst
      841 drkmtllhyi anvvkdkyqq vslfynelny vekaaavsle nvlldvkelq rgmdlmrrey
      901 smhghntllr dfiqqnenkl kklqddakia qdafdevvkf fgenakttpp svffpvfvrf
      961 vkayrqaeed neqrkrqeqm mmeklieqea mmalvdqksp shkskrqqqe liaelrkkqv
     1021 kdsrhvyegk dgaiediitd lrnqpyrrad avrrsirrrf ddqnlrpmnn aemvm
//
LOCUS       XP_026128531            1070 aa            linear   VRT 18-JUN-2025
DEFINITION  formin-like protein 2 isoform X2 [Carassius auratus].
ACCESSION   XP_026128531
VERSION     XP_026128531.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272746.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1070
                     /product="formin-like protein 2 isoform X2"
                     /calculated_mol_wt=121523
     Region          22..275
                     /region_name="Drf_GBD"
                     /note="Diaphanous GTPase-binding Domain; pfam06371"
                     /db_xref="CDD:461886"
     Region          278..475
                     /region_name="Drf_FH3"
                     /note="Diaphanous FH3 Domain; pfam06367"
                     /db_xref="CDD:461885"
     Region          599..950
                     /region_name="FH2"
                     /note="Formin Homology 2 Domain; pfam02181"
                     /db_xref="CDD:396655"
     CDS             1..1070
                     /gene="LOC113109159"
                     /coded_by="XM_026272746.1:1..3213"
                     /db_xref="GeneID:113109159"
ORIGIN      
        1 mgnagslnqh tdprghhmpl klpmpepael edrfalvlns mnlppdkarl lrqydnekkw
       61 elicdqerfq vknpphtyih klqgyldpav trkkfrrrvq estqvlrele islrtnhigw
      121 vreflneenk gldvlveyls faqyavtydg dssesstens vdkskpwnrs iedlhggnhl
      181 ssavtgssis rasrhstirs ntlpsrrtlk nsrlvckkdd lhvcimclra imnyqygfnm
      241 vmshphavne ialslnnknp rtkalvlell aavclvrggh eiilsafdhf kevcledqrf
      301 eklmehfkne dnnidfmvac mqfinivvhs vedmnfrvhl qydftklgld eyldklkhte
      361 sdklhvqiqa yldnvfdvga lledaetkna alerveelee nmshlteklq dteneamaki
      421 velekqlmqk nkeldsvrev ykdassqvht lrrmvkekde aiqkqsnlek kihelekqgt
      481 ikiqkkadgd iailtpppqg nghlpgsqgv aggsregaaq gltvpdpppp pppppmpetl
      541 pngpsapppp pplpavdisa pmppppppma pplpgcgspt vimnsglaeg piklcsvkik
      601 kpiktkfrmp vfnwvalkpn qingtvfnei dderiledln vdefeemfkt kaqgpaidit
      661 sskqktsqkg pckvslldsn raknlaitlr kvgktseeic raiqmfdlrt lpvdfveclm
      721 rfvpteaelk vlrqyekerk plenltdedr fmihfskier lmqkmtimaf vgnftesvqm
      781 ltpqlhavia asvsikssqk lkkileiila lgnymnsskr gavygfklqs ldllldtkst
      841 drkmtllhyi anvvkdkyqq vslfynelny vekaaavsle nvlldvkelq rgmdlmrrey
      901 smhghntllr dfiqqnenkl kklqddakia qdafdevvkf fgenakttpp svffpvfvrf
      961 vkayrqaeed neqrkrqeqm mmeklieqea mmalvdqksp shkskrqqqe liaelrkkqv
     1021 kdsrhvyegk dgaiediita lkknnitkfp nvhsrvrnss sstpvdatqt
//
LOCUS       XP_026128532            1068 aa            linear   VRT 18-JUN-2025
DEFINITION  formin-like protein 2 isoform X3 [Carassius auratus].
ACCESSION   XP_026128532
VERSION     XP_026128532.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272747.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1068
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1068
                     /product="formin-like protein 2 isoform X3"
                     /calculated_mol_wt=121830
     Region          22..275
                     /region_name="Drf_GBD"
                     /note="Diaphanous GTPase-binding Domain; pfam06371"
                     /db_xref="CDD:461886"
     Region          278..475
                     /region_name="Drf_FH3"
                     /note="Diaphanous FH3 Domain; pfam06367"
                     /db_xref="CDD:461885"
     Region          592..943
                     /region_name="FH2"
                     /note="Formin Homology 2 Domain; pfam02181"
                     /db_xref="CDD:396655"
     CDS             1..1068
                     /gene="LOC113109159"
                     /coded_by="XM_026272747.1:283..3489"
                     /db_xref="GeneID:113109159"
ORIGIN      
        1 mgnagslnqh tdprghhmpl klpmpepael edrfalvlns mnlppdkarl lrqydnekkw
       61 elicdqerfq vknpphtyih klqgyldpav trkkfrrrvq estqvlrele islrtnhigw
      121 vreflneenk gldvlveyls faqyavtydg dssesstens vdkskpwnrs iedlhggnhl
      181 ssavtgssis rasrhstirs ntlpsrrtlk nsrlvckkdd lhvcimclra imnyqygfnm
      241 vmshphavne ialslnnknp rtkalvlell aavclvrggh eiilsafdhf kevcledqrf
      301 eklmehfkne dnnidfmvac mqfinivvhs vedmnfrvhl qydftklgld eyldklkhte
      361 sdklhvqiqa yldnvfdvga lledaetkna alerveelee nmshlteklq dteneamaki
      421 velekqlmqk nkeldsvrev ykdassqvht lrrmvkekde aiqkqsnlek kihelekqgt
      481 ikiqkkadgd iailtpppqg nghlpgsqgv aggsregaaq gltvpdpppp pppppmpetl
      541 pngpsapppp pplpavdisa pmppppppma pplpgcgspt vimnsglaav kikkpiktkf
      601 rmpvfnwval kpnqingtvf neidderile dlnvdefeem fktkaqgpai ditsskqkts
      661 qkgpckvsll dsnraknlai tlrkvgktse eicraiqmfd lrtlpvdfve clmrfvptea
      721 elkvlrqyek erkplenltd edrfmihfsk ierlmqkmti mafvgnftes vqmltpqlha
      781 viaasvsiks sqklkkilei ilalgnymns skrgavygfk lqsldllldt kstdrkmtll
      841 hyianvvkdk yqqvslfyne lnyvekaaav slenvlldvk elqrgmdlmr reysmhghnt
      901 llrdfiqqne nklkklqdda kiaqdafdev vkffgenakt tppsvffpvf vrfvkayrqa
      961 eedneqrkrq eqmmmeklie qeammalvdq kspshkskrq qqeliaelrk kqvkdsrhvy
     1021 egkdgaiedi itdlrnqpyr radavrrsir rrfddqnlrp mnnaemvm
//
LOCUS       XP_026128533            1064 aa            linear   VRT 18-JUN-2025
DEFINITION  formin-like protein 2 isoform X4 [Carassius auratus].
ACCESSION   XP_026128533
VERSION     XP_026128533.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272748.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1064
                     /product="formin-like protein 2 isoform X4"
                     /calculated_mol_wt=121095
     Region          22..275
                     /region_name="Drf_GBD"
                     /note="Diaphanous GTPase-binding Domain; pfam06371"
                     /db_xref="CDD:461886"
     Region          278..475
                     /region_name="Drf_FH3"
                     /note="Diaphanous FH3 Domain; pfam06367"
                     /db_xref="CDD:461885"
     Region          599..950
                     /region_name="FH2"
                     /note="Formin Homology 2 Domain; pfam02181"
                     /db_xref="CDD:396655"
     CDS             1..1064
                     /gene="LOC113109159"
                     /coded_by="XM_026272748.1:283..3477"
                     /db_xref="GeneID:113109159"
ORIGIN      
        1 mgnagslnqh tdprghhmpl klpmpepael edrfalvlns mnlppdkarl lrqydnekkw
       61 elicdqerfq vknpphtyih klqgyldpav trkkfrrrvq estqvlrele islrtnhigw
      121 vreflneenk gldvlveyls faqyavtydg dssesstens vdkskpwnrs iedlhggnhl
      181 ssavtgssis rasrhstirs ntlpsrrtlk nsrlvckkdd lhvcimclra imnyqygfnm
      241 vmshphavne ialslnnknp rtkalvlell aavclvrggh eiilsafdhf kevcledqrf
      301 eklmehfkne dnnidfmvac mqfinivvhs vedmnfrvhl qydftklgld eyldklkhte
      361 sdklhvqiqa yldnvfdvga lledaetkna alerveelee nmshlteklq dteneamaki
      421 velekqlmqk nkeldsvrev ykdassqvht lrrmvkekde aiqkqsnlek kihelekqgt
      481 ikiqkkadgd iailtpppqg nghlpgsqgv aggsregaaq gltvpdpppp pppppmpetl
      541 pngpsapppp pplpavdisa pmppppppma pplpgcgspt vimnsglaeg piklcsvkik
      601 kpiktkfrmp vfnwvalkpn qingtvfnei dderiledln vdefeemfkt kaqgpaidit
      661 sskqktsqkg pckvslldsn raknlaitlr kvgktseeic raiqmfdlrt lpvdfveclm
      721 rfvpteaelk vlrqyekerk plenltdedr fmihfskier lmqkmtimaf vgnftesvqm
      781 ltpqlhavia asvsikssqk lkkileiila lgnymnsskr gavygfklqs ldllldtkst
      841 drkmtllhyi anvvkdkyqq vslfynelny vekaaavsle nvlldvkelq rgmdlmrrey
      901 smhghntllr dfiqqnenkl kklqddakia qdafdevvkf fgenakttpp svffpvfvrf
      961 vkayrqaeed neqrkrqeqm mmeklieqea mmalvdqksp shkskrqqqe liaelrkkqv
     1021 kdsrhvyegk dgaiediitv lktapftart akrssryfne elhf
//
LOCUS       XP_026128534            1064 aa            linear   VRT 18-JUN-2025
DEFINITION  formin-like protein 2 isoform X4 [Carassius auratus].
ACCESSION   XP_026128534
VERSION     XP_026128534.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272749.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1064
                     /product="formin-like protein 2 isoform X4"
                     /calculated_mol_wt=121095
     Region          22..275
                     /region_name="Drf_GBD"
                     /note="Diaphanous GTPase-binding Domain; pfam06371"
                     /db_xref="CDD:461886"
     Region          278..475
                     /region_name="Drf_FH3"
                     /note="Diaphanous FH3 Domain; pfam06367"
                     /db_xref="CDD:461885"
     Region          599..950
                     /region_name="FH2"
                     /note="Formin Homology 2 Domain; pfam02181"
                     /db_xref="CDD:396655"
     CDS             1..1064
                     /gene="LOC113109159"
                     /coded_by="XM_026272749.1:283..3477"
                     /db_xref="GeneID:113109159"
ORIGIN      
        1 mgnagslnqh tdprghhmpl klpmpepael edrfalvlns mnlppdkarl lrqydnekkw
       61 elicdqerfq vknpphtyih klqgyldpav trkkfrrrvq estqvlrele islrtnhigw
      121 vreflneenk gldvlveyls faqyavtydg dssesstens vdkskpwnrs iedlhggnhl
      181 ssavtgssis rasrhstirs ntlpsrrtlk nsrlvckkdd lhvcimclra imnyqygfnm
      241 vmshphavne ialslnnknp rtkalvlell aavclvrggh eiilsafdhf kevcledqrf
      301 eklmehfkne dnnidfmvac mqfinivvhs vedmnfrvhl qydftklgld eyldklkhte
      361 sdklhvqiqa yldnvfdvga lledaetkna alerveelee nmshlteklq dteneamaki
      421 velekqlmqk nkeldsvrev ykdassqvht lrrmvkekde aiqkqsnlek kihelekqgt
      481 ikiqkkadgd iailtpppqg nghlpgsqgv aggsregaaq gltvpdpppp pppppmpetl
      541 pngpsapppp pplpavdisa pmppppppma pplpgcgspt vimnsglaeg piklcsvkik
      601 kpiktkfrmp vfnwvalkpn qingtvfnei dderiledln vdefeemfkt kaqgpaidit
      661 sskqktsqkg pckvslldsn raknlaitlr kvgktseeic raiqmfdlrt lpvdfveclm
      721 rfvpteaelk vlrqyekerk plenltdedr fmihfskier lmqkmtimaf vgnftesvqm
      781 ltpqlhavia asvsikssqk lkkileiila lgnymnsskr gavygfklqs ldllldtkst
      841 drkmtllhyi anvvkdkyqq vslfynelny vekaaavsle nvlldvkelq rgmdlmrrey
      901 smhghntllr dfiqqnenkl kklqddakia qdafdevvkf fgenakttpp svffpvfvrf
      961 vkayrqaeed neqrkrqeqm mmeklieqea mmalvdqksp shkskrqqqe liaelrkkqv
     1021 kdsrhvyegk dgaiediitv lktapftart akrssryfne elhf
//
LOCUS       XP_026128535            1063 aa            linear   VRT 18-JUN-2025
DEFINITION  formin-like protein 2 isoform X5 [Carassius auratus].
ACCESSION   XP_026128535
VERSION     XP_026128535.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272750.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1063
                     /product="formin-like protein 2 isoform X5"
                     /calculated_mol_wt=120766
     Region          22..275
                     /region_name="Drf_GBD"
                     /note="Diaphanous GTPase-binding Domain; pfam06371"
                     /db_xref="CDD:461886"
     Region          278..475
                     /region_name="Drf_FH3"
                     /note="Diaphanous FH3 Domain; pfam06367"
                     /db_xref="CDD:461885"
     Region          592..943
                     /region_name="FH2"
                     /note="Formin Homology 2 Domain; pfam02181"
                     /db_xref="CDD:396655"
     CDS             1..1063
                     /gene="LOC113109159"
                     /coded_by="XM_026272750.1:1..3192"
                     /db_xref="GeneID:113109159"
ORIGIN      
        1 mgnagslnqh tdprghhmpl klpmpepael edrfalvlns mnlppdkarl lrqydnekkw
       61 elicdqerfq vknpphtyih klqgyldpav trkkfrrrvq estqvlrele islrtnhigw
      121 vreflneenk gldvlveyls faqyavtydg dssesstens vdkskpwnrs iedlhggnhl
      181 ssavtgssis rasrhstirs ntlpsrrtlk nsrlvckkdd lhvcimclra imnyqygfnm
      241 vmshphavne ialslnnknp rtkalvlell aavclvrggh eiilsafdhf kevcledqrf
      301 eklmehfkne dnnidfmvac mqfinivvhs vedmnfrvhl qydftklgld eyldklkhte
      361 sdklhvqiqa yldnvfdvga lledaetkna alerveelee nmshlteklq dteneamaki
      421 velekqlmqk nkeldsvrev ykdassqvht lrrmvkekde aiqkqsnlek kihelekqgt
      481 ikiqkkadgd iailtpppqg nghlpgsqgv aggsregaaq gltvpdpppp pppppmpetl
      541 pngpsapppp pplpavdisa pmppppppma pplpgcgspt vimnsglaav kikkpiktkf
      601 rmpvfnwval kpnqingtvf neidderile dlnvdefeem fktkaqgpai ditsskqkts
      661 qkgpckvsll dsnraknlai tlrkvgktse eicraiqmfd lrtlpvdfve clmrfvptea
      721 elkvlrqyek erkplenltd edrfmihfsk ierlmqkmti mafvgnftes vqmltpqlha
      781 viaasvsiks sqklkkilei ilalgnymns skrgavygfk lqsldllldt kstdrkmtll
      841 hyianvvkdk yqqvslfyne lnyvekaaav slenvlldvk elqrgmdlmr reysmhghnt
      901 llrdfiqqne nklkklqdda kiaqdafdev vkffgenakt tppsvffpvf vrfvkayrqa
      961 eedneqrkrq eqmmmeklie qeammalvdq kspshkskrq qqeliaelrk kqvkdsrhvy
     1021 egkdgaiedi italkknnit kfpnvhsrvr nsssstpvda tqt
//
LOCUS       XP_026128536            1057 aa            linear   VRT 18-JUN-2025
DEFINITION  formin-like protein 2 isoform X6 [Carassius auratus].
ACCESSION   XP_026128536
VERSION     XP_026128536.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272751.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1057
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1057
                     /product="formin-like protein 2 isoform X6"
                     /calculated_mol_wt=120338
     Region          22..275
                     /region_name="Drf_GBD"
                     /note="Diaphanous GTPase-binding Domain; pfam06371"
                     /db_xref="CDD:461886"
     Region          278..475
                     /region_name="Drf_FH3"
                     /note="Diaphanous FH3 Domain; pfam06367"
                     /db_xref="CDD:461885"
     Region          592..943
                     /region_name="FH2"
                     /note="Formin Homology 2 Domain; pfam02181"
                     /db_xref="CDD:396655"
     CDS             1..1057
                     /gene="LOC113109159"
                     /coded_by="XM_026272751.1:1..3174"
                     /db_xref="GeneID:113109159"
ORIGIN      
        1 mgnagslnqh tdprghhmpl klpmpepael edrfalvlns mnlppdkarl lrqydnekkw
       61 elicdqerfq vknpphtyih klqgyldpav trkkfrrrvq estqvlrele islrtnhigw
      121 vreflneenk gldvlveyls faqyavtydg dssesstens vdkskpwnrs iedlhggnhl
      181 ssavtgssis rasrhstirs ntlpsrrtlk nsrlvckkdd lhvcimclra imnyqygfnm
      241 vmshphavne ialslnnknp rtkalvlell aavclvrggh eiilsafdhf kevcledqrf
      301 eklmehfkne dnnidfmvac mqfinivvhs vedmnfrvhl qydftklgld eyldklkhte
      361 sdklhvqiqa yldnvfdvga lledaetkna alerveelee nmshlteklq dteneamaki
      421 velekqlmqk nkeldsvrev ykdassqvht lrrmvkekde aiqkqsnlek kihelekqgt
      481 ikiqkkadgd iailtpppqg nghlpgsqgv aggsregaaq gltvpdpppp pppppmpetl
      541 pngpsapppp pplpavdisa pmppppppma pplpgcgspt vimnsglaav kikkpiktkf
      601 rmpvfnwval kpnqingtvf neidderile dlnvdefeem fktkaqgpai ditsskqkts
      661 qkgpckvsll dsnraknlai tlrkvgktse eicraiqmfd lrtlpvdfve clmrfvptea
      721 elkvlrqyek erkplenltd edrfmihfsk ierlmqkmti mafvgnftes vqmltpqlha
      781 viaasvsiks sqklkkilei ilalgnymns skrgavygfk lqsldllldt kstdrkmtll
      841 hyianvvkdk yqqvslfyne lnyvekaaav slenvlldvk elqrgmdlmr reysmhghnt
      901 llrdfiqqne nklkklqdda kiaqdafdev vkffgenakt tppsvffpvf vrfvkayrqa
      961 eedneqrkrq eqmmmeklie qeammalvdq kspshkskrq qqeliaelrk kqvkdsrhvy
     1021 egkdgaiedi itvlktapft artakrssry fneelhf
//
LOCUS       XP_026128537            1056 aa            linear   VRT 18-JUN-2025
DEFINITION  formin-like protein 2 isoform X7 [Carassius auratus].
ACCESSION   XP_026128537
VERSION     XP_026128537.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272752.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1056
                     /product="formin-like protein 2 isoform X7"
                     /calculated_mol_wt=120105
     Region          22..275
                     /region_name="Drf_GBD"
                     /note="Diaphanous GTPase-binding Domain; pfam06371"
                     /db_xref="CDD:461886"
     Region          278..475
                     /region_name="Drf_FH3"
                     /note="Diaphanous FH3 Domain; pfam06367"
                     /db_xref="CDD:461885"
     Region          599..950
                     /region_name="FH2"
                     /note="Formin Homology 2 Domain; pfam02181"
                     /db_xref="CDD:396655"
     CDS             1..1056
                     /gene="LOC113109159"
                     /coded_by="XM_026272752.1:1..3171"
                     /db_xref="GeneID:113109159"
ORIGIN      
        1 mgnagslnqh tdprghhmpl klpmpepael edrfalvlns mnlppdkarl lrqydnekkw
       61 elicdqerfq vknpphtyih klqgyldpav trkkfrrrvq estqvlrele islrtnhigw
      121 vreflneenk gldvlveyls faqyavtydg dssesstens vdkskpwnrs iedlhggnhl
      181 ssavtgssis rasrhstirs ntlpsrrtlk nsrlvckkdd lhvcimclra imnyqygfnm
      241 vmshphavne ialslnnknp rtkalvlell aavclvrggh eiilsafdhf kevcledqrf
      301 eklmehfkne dnnidfmvac mqfinivvhs vedmnfrvhl qydftklgld eyldklkhte
      361 sdklhvqiqa yldnvfdvga lledaetkna alerveelee nmshlteklq dteneamaki
      421 velekqlmqk nkeldsvrev ykdassqvht lrrmvkekde aiqkqsnlek kihelekqgt
      481 ikiqkkadgd iailtpppqg nghlpgsqgv aggsregaaq gltvpdpppp pppppmpetl
      541 pngpsapppp pplpavdisa pmppppppma pplpgcgspt vimnsglaeg piklcsvkik
      601 kpiktkfrmp vfnwvalkpn qingtvfnei dderiledln vdefeemfkt kaqgpaidit
      661 sskqktsqkg pckvslldsn raknlaitlr kvgktseeic raiqmfdlrt lpvdfveclm
      721 rfvpteaelk vlrqyekerk plenltdedr fmihfskier lmqkmtimaf vgnftesvqm
      781 ltpqlhavia asvsikssqk lkkileiila lgnymnsskr gavygfklqs ldllldtkst
      841 drkmtllhyi anvvkdkyqq vslfynelny vekaaavsle nvlldvkelq rgmdlmrrey
      901 smhghntllr dfiqqnenkl kklqddakia qdafdevvkf fgenakttpp svffpvfvrf
      961 vkayrqaeed neqrkrqeqm mmeklieqea mmalvdqksp shkskrqqqe liaelrkkqv
     1021 kdsrhvyegk dgaiediita lkknnitkfp nvhsri
//
LOCUS       XP_026128538            1819 aa            linear   VRT 18-JUN-2025
DEFINITION  myosin light chain kinase, smooth muscle isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128538
VERSION     XP_026128538.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272753.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1819
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1819
                     /product="myosin light chain kinase, smooth muscle isoform
                     X1"
                     /calculated_mol_wt=200895
     Region          44..134
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          61..65
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409565"
     Region          74..78
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409565"
     Region          100..104
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409565"
     Region          114..119
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409565"
     Region          127..130
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409565"
     Region          171..259
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          188..192
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          201..205
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          226..230
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          240..245
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          253..256
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          405..494
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          422..426
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409564"
     Region          435..439
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409564"
     Region          460..464
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409564"
     Region          474..479
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409564"
     Region          503..590
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          521..525
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409568"
     Region          534..538
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409568"
     Region          556..560
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409568"
     Region          570..575
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409568"
     Region          583..586
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409568"
     Region          613..702
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          630..634
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409570"
     Region          643..647
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409570"
     Region          668..672
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409570"
     Region          682..687
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409570"
     Region          695..698
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409570"
     Region          711..800
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          728..732
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          741..745
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          766..770
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          780..785
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          1026..1114
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          1042..1046
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          1055..1059
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          1080..1084
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          1094..1099
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          1155..1253
                     /region_name="IgI_8_hMLCK_like"
                     /note="Eighth immunoglobulin (Ig)-like domain of human
                     myosin light-chain kinase (MLCK) and similar protein;
                     member of the I-set of IgSF domains; cd05762"
                     /db_xref="CDD:409419"
     Region          1155..1159
                     /region_name="Ig strand A"
                     /note="Ig strand A [structural motif]"
                     /db_xref="CDD:409419"
     Region          1164..1168
                     /region_name="Ig strand A'"
                     /note="Ig strand A' [structural motif]"
                     /db_xref="CDD:409419"
     Region          1172..1181
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409419"
     Region          1185..1191
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409419"
     Region          1194..1196
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409419"
     Region          1202..1207
                     /region_name="Ig strand D"
                     /note="Ig strand D [structural motif]"
                     /db_xref="CDD:409419"
     Region          1211..1216
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409419"
     Region          1224..1232
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409419"
     Region          1235..1245
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409419"
     Region          1249..1342
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(1249,1314,1329)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(1330..1331,1333..1334)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          1379..1637
                     /region_name="STKc_MLCK1"
                     /note="Catalytic domain of the Serine/Threonine Kinase,
                     Myosin Light Chain Kinase 1; cd14191"
                     /db_xref="CDD:271093"
     Site            order(1388..1392,1394,1396,1409,1411,1440,1456..1457,1459,
                     1463,1465,1503,1505,1507..1508,1510,1522..1523,1526,
                     1541..1544)
                     /site_type="active"
                     /db_xref="CDD:271093"
     Site            order(1388..1392,1394,1396,1409,1411,1440,1456..1457,1459,
                     1463,1507..1508,1510,1522..1523)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271093"
     Site            order(1392,1463,1465,1503,1505,1507,1526,1541..1544)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271093"
     Site            1522..1544
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271093"
     Region          1717..1801
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          1728..1732
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409565"
     Region          1741..1745
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409565"
     Region          1767..1771
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409565"
     Region          1781..1786
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409565"
     Region          1794..1797
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409565"
     CDS             1..1819
                     /gene="LOC113109161"
                     /coded_by="XM_026272753.1:119..5578"
                     /db_xref="GeneID:113109161"
ORIGIN      
        1 mtdtnlsslt rlsgtmgdvq fvtgshvskt tltlgrgshs keppvftlpp rntricqggt
       61 arlegkvrgf pepqvcwfrn eklliagdhy smeqsargsf hlvvhdvqdd dggrytceav
      121 ndagrcqvtv eiivegnagk kyslpssnra ggslgipave nrpsiwgesp pkfvtkpsrl
      181 ylklgqsgkf sakitgrpqp lvqwykgeek iqqsdhfnif drsgmhflei rhmcsedagv
      241 ytclvansag kasaaaelia qdgvpetvtm pkpsqdlstq svvkhstngl dteqkassts
      301 frtastetra plstttvasv qsvtrteepk itptpssqpi sistdgrsaa gqktsmfvne
      361 rsrnvvkkes hvkrrapeei peasqqessg dstkesttdf letpptfesq pesqeavqgq
      421 kvtfrcqvsg spvptvswvk dgapvrqrsg istrlegslh vlclesahit dtgqysctaa
      481 nkrgkteahw sltvkrvrve vkppvfsspl kdcsvlegqd fmlqcsvegk plpeltwlhn
      541 dqpvpyphtv fensmalltv kaavlddagm yscvavnnqg tavctahvlv kakagvkrsa
      601 appvtdvrrp svpvflrglq dlrvmdgcqv tmtvevtgnp apeviwlhng keiqesedfh
      661 ferkgcqhtl fiqevfpedt gtytcevwne agvarteasl tvqepqdgvq pwfitktkst
      721 aaslgqhall scaiagdpfp eflwmkdgqv isgggdfeil qkedvvslli rkvetyhagn
      781 yeihlknkig ecrsvaalhi cedpmssvdd shkrsrgver taagrggqpe tpstavslse
      841 plwehnskdp eeeegcasrg llkrrvetke hredqirqqe aeqidfrtvl grkvttksvs
      901 eedlkeitae qmdfrgnlqr qikpktqtee erkvnspqqv dfravlgkkg sqgpkpglgs
      961 lvktqankte avdfrsvlgn kkkqpcldrn gesqgdkdtr gkkndvncvd ggikektkaa
     1021 gkkelvftqk lsdvrvldge rlhlqcqlss espakvtwtl dgklikpskf iiiadeggkc
     1081 slsidkalpe degqyvcrae tnegktecsc mvlvddpsvs tpadkrsrkp stpttenear
     1141 ikkptpktlp kqgappqilq fpddmkilag qevsllcrft gaqpisctwl kfrkpiqegq
     1201 gisivstdss sqltitegqq ehcgcytiel knscgvrqaa lnltivdkpd pparvpaasd
     1261 irkssltlsw ygptydggsa vqtynlemws svdmkwtdla scnstsynvq nllpdrqykf
     1321 rvravniygv gepsaesvpv qvgpeaeeen kdeaepsdde sekepdyrsv tirtdvkvkd
     1381 lydvedrlgt gkfgtvfkli ekstkkvwag kfikaysake kdnvrqeiai mndlrhpklv
     1441 qcvdafegkt divmvlemvs ggelferiid edfelterev ikymlqivdg vsfihkkgiv
     1501 hldlkpenim cvnktgskik lidfglarrl enagslkvlf gtpefvapev inyeaisyat
     1561 dmwsigvicy ilvsglspfm gdndnetlsn vtsatwdfed eafdeisdea kdfisnllkk
     1621 dmkarlscdq cfqhpwlkqd ttnmevkkls kermkkyilr rkwqktghav raigrlsnma
     1681 llagvhakkg spteedkqfs aelvekplmk ptfssvikdv evvegsaarf dckiegypdp
     1741 evvwykddqp iketrhfqid ydedgncslv isevsgddda kytckamnsv geatctaeli
     1801 vevmgageee eeeeeeeee
//
LOCUS       XP_026128539            1818 aa            linear   VRT 18-JUN-2025
DEFINITION  myosin light chain kinase, smooth muscle isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128539
VERSION     XP_026128539.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272754.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1818
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1818
                     /product="myosin light chain kinase, smooth muscle isoform
                     X2"
                     /calculated_mol_wt=200808
     Region          44..134
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          61..65
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409565"
     Region          74..78
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409565"
     Region          100..104
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409565"
     Region          114..119
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409565"
     Region          127..130
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409565"
     Region          171..259
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          188..192
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          201..205
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          226..230
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          240..245
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          253..256
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          405..494
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          422..426
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409564"
     Region          435..439
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409564"
     Region          460..464
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409564"
     Region          474..479
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409564"
     Region          503..590
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          521..525
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409568"
     Region          534..538
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409568"
     Region          556..560
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409568"
     Region          570..575
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409568"
     Region          583..586
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409568"
     Region          613..702
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          630..634
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409570"
     Region          643..647
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409570"
     Region          668..672
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409570"
     Region          682..687
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409570"
     Region          695..698
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409570"
     Region          711..800
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          728..732
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          741..745
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          766..770
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          780..785
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          1025..1113
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          1041..1045
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          1054..1058
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          1079..1083
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          1093..1098
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          1154..1252
                     /region_name="IgI_8_hMLCK_like"
                     /note="Eighth immunoglobulin (Ig)-like domain of human
                     myosin light-chain kinase (MLCK) and similar protein;
                     member of the I-set of IgSF domains; cd05762"
                     /db_xref="CDD:409419"
     Region          1154..1158
                     /region_name="Ig strand A"
                     /note="Ig strand A [structural motif]"
                     /db_xref="CDD:409419"
     Region          1163..1167
                     /region_name="Ig strand A'"
                     /note="Ig strand A' [structural motif]"
                     /db_xref="CDD:409419"
     Region          1171..1180
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409419"
     Region          1184..1190
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409419"
     Region          1193..1195
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409419"
     Region          1201..1206
                     /region_name="Ig strand D"
                     /note="Ig strand D [structural motif]"
                     /db_xref="CDD:409419"
     Region          1210..1215
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409419"
     Region          1223..1231
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409419"
     Region          1234..1244
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409419"
     Region          1248..1341
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(1248,1313,1328)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(1329..1330,1332..1333)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          1378..1636
                     /region_name="STKc_MLCK1"
                     /note="Catalytic domain of the Serine/Threonine Kinase,
                     Myosin Light Chain Kinase 1; cd14191"
                     /db_xref="CDD:271093"
     Site            order(1387..1391,1393,1395,1408,1410,1439,1455..1456,1458,
                     1462,1464,1502,1504,1506..1507,1509,1521..1522,1525,
                     1540..1543)
                     /site_type="active"
                     /db_xref="CDD:271093"
     Site            order(1387..1391,1393,1395,1408,1410,1439,1455..1456,1458,
                     1462,1506..1507,1509,1521..1522)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:271093"
     Site            order(1391,1462,1464,1502,1504,1506,1525,1540..1543)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:271093"
     Site            1521..1543
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:271093"
     Region          1716..1800
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          1727..1731
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409565"
     Region          1740..1744
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409565"
     Region          1766..1770
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409565"
     Region          1780..1785
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409565"
     Region          1793..1796
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409565"
     CDS             1..1818
                     /gene="LOC113109161"
                     /coded_by="XM_026272754.1:119..5575"
                     /db_xref="GeneID:113109161"
ORIGIN      
        1 mtdtnlsslt rlsgtmgdvq fvtgshvskt tltlgrgshs keppvftlpp rntricqggt
       61 arlegkvrgf pepqvcwfrn eklliagdhy smeqsargsf hlvvhdvqdd dggrytceav
      121 ndagrcqvtv eiivegnagk kyslpssnra ggslgipave nrpsiwgesp pkfvtkpsrl
      181 ylklgqsgkf sakitgrpqp lvqwykgeek iqqsdhfnif drsgmhflei rhmcsedagv
      241 ytclvansag kasaaaelia qdgvpetvtm pkpsqdlstq svvkhstngl dteqkassts
      301 frtastetra plstttvasv qsvtrteepk itptpssqpi sistdgrsaa gqktsmfvne
      361 rsrnvvkkes hvkrrapeei peasqqessg dstkesttdf letpptfesq pesqeavqgq
      421 kvtfrcqvsg spvptvswvk dgapvrqrsg istrlegslh vlclesahit dtgqysctaa
      481 nkrgkteahw sltvkrvrve vkppvfsspl kdcsvlegqd fmlqcsvegk plpeltwlhn
      541 dqpvpyphtv fensmalltv kaavlddagm yscvavnnqg tavctahvlv kakagvkrsa
      601 appvtdvrrp svpvflrglq dlrvmdgcqv tmtvevtgnp apeviwlhng keiqesedfh
      661 ferkgcqhtl fiqevfpedt gtytcevwne agvarteasl tvqepqdgvq pwfitktkst
      721 aaslgqhall scaiagdpfp eflwmkdgqv isgggdfeil qkedvvslli rkvetyhagn
      781 yeihlknkig ecrsvaalhi cedpmssvdd shkrrgvert aagrggqpet pstavslsep
      841 lwehnskdpe eeegcasrgl lkrrvetkeh redqirqqea eqidfrtvlg rkvttksvse
      901 edlkeitaeq mdfrgnlqrq ikpktqteee rkvnspqqvd fravlgkkgs qgpkpglgsl
      961 vktqanktea vdfrsvlgnk kkqpcldrng esqgdkdtrg kkndvncvdg gikektkaag
     1021 kkelvftqkl sdvrvldger lhlqcqlsse spakvtwtld gklikpskfi iiadeggkcs
     1081 lsidkalped egqyvcraet negktecscm vlvddpsvst padkrsrkps tptteneari
     1141 kkptpktlpk qgappqilqf pddmkilagq evsllcrftg aqpisctwlk frkpiqegqg
     1201 isivstdsss qltitegqqe hcgcytielk nscgvrqaal nltivdkpdp parvpaasdi
     1261 rkssltlswy gptydggsav qtynlemwss vdmkwtdlas cnstsynvqn llpdrqykfr
     1321 vravniygvg epsaesvpvq vgpeaeeenk deaepsddes ekepdyrsvt irtdvkvkdl
     1381 ydvedrlgtg kfgtvfklie kstkkvwagk fikaysakek dnvrqeiaim ndlrhpklvq
     1441 cvdafegktd ivmvlemvsg gelferiide dfelterevi kymlqivdgv sfihkkgivh
     1501 ldlkpenimc vnktgskikl idfglarrle nagslkvlfg tpefvapevi nyeaisyatd
     1561 mwsigvicyi lvsglspfmg dndnetlsnv tsatwdfede afdeisdeak dfisnllkkd
     1621 mkarlscdqc fqhpwlkqdt tnmevkklsk ermkkyilrr kwqktghavr aigrlsnmal
     1681 lagvhakkgs pteedkqfsa elvekplmkp tfssvikdve vvegsaarfd ckiegypdpe
     1741 vvwykddqpi ketrhfqidy dedgncslvi sevsgdddak ytckamnsvg eatctaeliv
     1801 evmgageeee eeeeeeee
//
LOCUS       XP_026128541            2974 aa            linear   VRT 18-JUN-2025
DEFINITION  kalirin-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128541
VERSION     XP_026128541.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272756.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2974
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2974
                     /product="kalirin-like isoform X1"
                     /calculated_mol_wt=335889
     Region          39..177
                     /region_name="SEC14"
                     /note="Domain in homologues of a S. cerevisiae
                     phosphatidylinositol transfer protein (Sec14p);
                     smart00516"
                     /db_xref="CDD:214706"
     Region          190..410
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Site            309..314
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          311..536
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Site            417..422
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          537..753
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Region          878..1116
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Site            992..997
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          1122..1222
                     /region_name="SPEC"
                     /note="Spectrin repeats; smart00150"
                     /db_xref="CDD:197544"
     Site            1224..1229
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          1271..1441
                     /region_name="RhoGEF"
                     /note="Guanine nucleotide exchange factor for
                     Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous
                     (DH) domain. It appears that PH domains invariably occur
                     C-terminal to RhoGEF/DH domains; cd00160"
                     /db_xref="CDD:238091"
     Site            order(1275,1279,1374,1395..1396,1399..1400,1402..1403,
                     1406..1407,1410..1411,1414,1437,1441)
                     /site_type="other"
                     /note="GTPase interaction site [polypeptide binding]"
                     /db_xref="CDD:238091"
     Region          1448..1570
                     /region_name="PH1_Kalirin_Trio_like"
                     /note="Triple functional domain pleckstrin homology
                     pleckstrin homology (PH) domain, repeat 1; cd13240"
                     /db_xref="CDD:270060"
     Site            order(1465,1505,1507)
                     /site_type="other"
                     /note="Rac1 binding site [polypeptide binding]"
                     /db_xref="CDD:270060"
     Region          1636..1695
                     /region_name="SH3_Kalirin_1"
                     /note="First Src homology 3 domain of the RhoGEF kinase,
                     Kalirin; cd11852"
                     /db_xref="CDD:212786"
     Site            order(1642,1644,1647,1651,1671..1672,1689,1691..1692)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212786"
     Region          1693..1921
                     /region_name="SH3-RhoG_link"
                     /note="SH3-RhoGEF linking unstructured region; pfam16609"
                     /db_xref="CDD:465196"
     Region          1922..2091
                     /region_name="RhoGEF"
                     /note="RhoGEF domain; pfam00621"
                     /db_xref="CDD:459876"
     Region          2096..2230
                     /region_name="PH2_Kalirin_Trio_p63RhoGEF"
                     /note="p63RhoGEF pleckstrin homology (PH) domain, repeat
                     2; cd13241"
                     /db_xref="CDD:270061"
     Site            order(2105,2140..2141,2165,2167,2217,2220..2222,
                     2224..2225,2227..2229)
                     /site_type="other"
                     /note="Galpha i/q binding site [polypeptide binding]"
                     /db_xref="CDD:270061"
     Region          2307..2365
                     /region_name="SH3_Kalirin_2"
                     /note="Second Src homology 3 domain of the RhoGEF kinase,
                     Kalirin; cd11853"
                     /db_xref="CDD:212787"
     Site            order(2312,2314,2317,2321,2339..2340,2359,2361..2362)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212787"
     Region          2462..2553
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          2479..2483
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409570"
     Region          2507..2511
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409570"
     Region          2533..2538
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409570"
     Region          2546..2549
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409570"
     Region          2557..2649
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(2557,2622,2637)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(2638..2639,2641..2642)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          2678..2925
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(2678..2681,2684,2686,2699,2701,2729,2745..2748,2791,
                     2795..2796,2798,2811..2812)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..2974
                     /gene="LOC113109162"
                     /coded_by="XM_026272756.1:345..9269"
                     /db_xref="GeneID:113109162"
ORIGIN      
        1 mnsaeaaedg pndsdtdaff ktgsfrsegi kasdvlpvlr ekvafvsggr dkrggpiltf
       61 parsnhdrik qedlrrlvty lstvpsedvc krgftviidm rgskwdlikp llktlqeafp
      121 aeicvaliik pdnfwqkqkt nfgsakftfe tsmvsveglt klvdpsqlte dfegsleynh
      181 eewielrval eeflasaihl lsrledlqem lakkefpvdv egsrrlideh tqlkkkvmka
      241 pveeldhegq rllqcirssd gfsgrncisg sadfqsvvpk iaslldklhs trqhlhqmwh
      301 lrklkldqcf qlrlfeqdae kmfdwishnk elflqshtei gvsyqhamel qtqhnhfamn
      361 smnayvninr imsvasrlse aghyasqqik qistqldqew ksfaaalder stilamsavf
      421 hqkseqflsg veawckmcse gglpsemqdl elaihhhqtl yeqvtqayte vsqdgkalld
      481 vlqrplspgn sesltatany skavhcildv vhevlhhqrr lesiwqhrkv rlhqrlqlcv
      541 fqqdvqqvid wienhgeafl skhtgvgksl hraralqkrh ddfeevaqnt ytnadkllea
      601 aeqlaqtgec dpeeiykaar hlevriqdfv rrveqrklll dmsvsfhtht kelwtwmedl
      661 qkelleevcs dsvdsvqeli kqfqqqqtat leatlnvike gedlmqqlrd samssnkmph
      721 tssiahiegv lqqldeaqgh meelfherki kldiflqlri feqytievta eldawnedlv
      781 rqvnefttee pslaeqrlqr haerklamnn mtyevmqqgq dlhqyimevq asgieltgek
      841 evdlatqvqe lleflnekqh eldvsaehtq khleqcvqlr hlqaevkqvl gwirngesml
      901 dasmvnassl seaeqlqreh eqfqlaiesl fhanslqkth qsalqvqqka eillqaghfd
      961 peairscaek vavhwqqlml kmedrlklvn asvafyktse qvcsvlesle qeyrrdedwc
     1021 gahdklgssa emdhvlplis khleqkeafl kactlarrna evflkyihrn nvssqgsssn
     1081 prgpeqqvka ilnellqren rvlhfwtmkk rrldqcqqyv vfersakqal ewieeagevy
     1141 lashtspgds vektqellke yeevrvsakq tkekvkmliq ladnfvekgh thvtelkkwv
     1201 tavdkryrdf slrmgkyrcs lenalgisse dnkdleldii pasltdpevk lrdpnheine
     1261 ekrksarkke fiiaellqte kayvrdlhec letylwgmtn gveeippgia nkehiifgni
     1321 qeiydfhnni flkelinyeq lpedvghcfv twadkfniyv tycknkpdss qlilehagsf
     1381 fdeiqkrhgl tnsissylik pvqritkyql llkellscce egkgeikdgl evmlsvpkra
     1441 ndamhvsmle gfdenldvqg elflqdtfqv wdpkslirkg rdrhlflfei slvfskeikd
     1501 sagrskyiyk nklltselgv tehvegdpck falwvgrtps sdnktvlkas sievkqewik
     1561 nireviqeri ihlkgalkep irvpktpakp rnnsrrdage dadsqgdgss qpdtisiasr
     1621 tsqntvdsdk lsggceltvv lqdfmassas elsvqtgqtv ellerpserp gwclvrttdk
     1681 tplqeglvps salcishsrs svemdcffpa gkenyavsgp egktesvttl qpqaslnslh
     1741 ssspgpkrsg ntlkkwltsp vrrlshgsni kkipskqkqk rdgrksidlg ppelqddtle
     1801 ervrkvegtl sksssgmhsg geeepedesh tplpppmeii kdpsaqeeks svllasrqss
     1861 advpsaaelv saieklvktk mtlepgsypg fssvnpaeqs papprnpele qkakalrgrm
     1921 fvvnelvqte kdyvkdlgiv veefmkiiee kgvpddmkgk dkivfgnihq iydwhkdffv
     1981 gelekcledh eklpglfskh errlhmyvvy cqnkpkseyi vaeydsyfee iqkdvssrls
     2041 isdflikpiq ritkyqlllk dflkysakag ldcqdiekav dlmsqvpklc ndmmnlgrlq
     2101 gfegkltsqg kllqqetffv teqdsgvlsr skerrvflfe qiiifsellr kgsstpgyqf
     2161 kksikvsflg leehvendpc kfvlscrgsa erftlqaant dvkqvwvqhi tklldlqsnf
     2221 lsalqspiey qkersgsqsl trnsssggrt gqsnsrpsst vslgaekpsl sgrsptpvkl
     2281 ttsssgpchd ryhrqfdgvg cngtssslmv tqdynalken eicvtqgetv qilatnqqnm
     2341 ylvyrpansq spaaegwvpg hilgplakpl idtaadsnik kslswntlra rkraekdcap
     2401 lksdikveng lrkpkeilss kvtvkpkpqd srssdesdye deldpktsme llnpnfiqev
     2461 apefltplad vtcalgetvv lcckvcarpk ptitlkgpdq sllvnnnrft iniresgdiv
     2521 lkicnlmpqd tgiytcvavn dhgtasssas ikvqgipaap arpvaqeass tavivhwlpp
     2581 assgnsaiss ytveyrqeds lvwqksvvst admcvkienl ipgghyqfrv sasnpwgisp
     2641 psepsnmvtl pstassydgt giqwkdnfes aftelceigr grfsvvrkcl skaskkevav
     2701 kfvnkkmqkk eqvgheadil rhvqhpqlva lidtyespma ymlvlelved grlldylvah
     2761 delmeekvaf fikdtlealq hlhtcrvahl dlkpenllvd lhvpvpcvkl sdlgdavqvs
     2821 shryvhlllg npefaapeli qgtpvslstd vwsvgvlayv mlsgvspfld esleetcvni
     2881 crldfcfpde yfsdisqaak dfivstlhqd prkrpssatc lqhpwvsahs gdysktpldt
     2941 vrlaafidrr kqlhdirpvt nvkglvsssm ghtl
//
LOCUS       XP_026128542            2942 aa            linear   VRT 18-JUN-2025
DEFINITION  kalirin-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128542
VERSION     XP_026128542.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272757.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2942
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2942
                     /product="kalirin-like isoform X2"
                     /calculated_mol_wt=332590
     Region          39..177
                     /region_name="SEC14"
                     /note="Domain in homologues of a S. cerevisiae
                     phosphatidylinositol transfer protein (Sec14p);
                     smart00516"
                     /db_xref="CDD:214706"
     Region          190..410
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Site            309..314
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          311..536
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Site            417..422
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          537..753
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Region          878..1116
                     /region_name="SPEC"
                     /note="Spectrin repeats, found in several proteins
                     involved in cytoskeletal structure; family members include
                     spectrin, alpha-actinin and dystrophin; the spectrin
                     repeat forms a three helix bundle with the second helix
                     interrupted by proline in some sequences; cd00176"
                     /db_xref="CDD:238103"
     Site            992..997
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          1122..1222
                     /region_name="SPEC"
                     /note="Spectrin repeats; smart00150"
                     /db_xref="CDD:197544"
     Site            1224..1229
                     /site_type="active"
                     /note="linker region [active]"
                     /db_xref="CDD:238103"
     Region          1271..1441
                     /region_name="RhoGEF"
                     /note="Guanine nucleotide exchange factor for
                     Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous
                     (DH) domain. It appears that PH domains invariably occur
                     C-terminal to RhoGEF/DH domains; cd00160"
                     /db_xref="CDD:238091"
     Site            order(1275,1279,1374,1395..1396,1399..1400,1402..1403,
                     1406..1407,1410..1411,1414,1437,1441)
                     /site_type="other"
                     /note="GTPase interaction site [polypeptide binding]"
                     /db_xref="CDD:238091"
     Region          1448..1570
                     /region_name="PH1_Kalirin_Trio_like"
                     /note="Triple functional domain pleckstrin homology
                     pleckstrin homology (PH) domain, repeat 1; cd13240"
                     /db_xref="CDD:270060"
     Site            order(1465,1505,1507)
                     /site_type="other"
                     /note="Rac1 binding site [polypeptide binding]"
                     /db_xref="CDD:270060"
     Region          1636..1695
                     /region_name="SH3_Kalirin_1"
                     /note="First Src homology 3 domain of the RhoGEF kinase,
                     Kalirin; cd11852"
                     /db_xref="CDD:212786"
     Site            order(1642,1644,1647,1651,1671..1672,1689,1691..1692)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212786"
     Region          1693..>1850
                     /region_name="SH3-RhoG_link"
                     /note="SH3-RhoGEF linking unstructured region; pfam16609"
                     /db_xref="CDD:465196"
     Region          1890..2059
                     /region_name="RhoGEF"
                     /note="RhoGEF domain; pfam00621"
                     /db_xref="CDD:459876"
     Region          2064..2198
                     /region_name="PH2_Kalirin_Trio_p63RhoGEF"
                     /note="p63RhoGEF pleckstrin homology (PH) domain, repeat
                     2; cd13241"
                     /db_xref="CDD:270061"
     Site            order(2073,2108..2109,2133,2135,2185,2188..2190,
                     2192..2193,2195..2197)
                     /site_type="other"
                     /note="Galpha i/q binding site [polypeptide binding]"
                     /db_xref="CDD:270061"
     Region          2275..2333
                     /region_name="SH3_Kalirin_2"
                     /note="Second Src homology 3 domain of the RhoGEF kinase,
                     Kalirin; cd11853"
                     /db_xref="CDD:212787"
     Site            order(2280,2282,2285,2289,2307..2308,2327,2329..2330)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212787"
     Region          2430..2521
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          2447..2451
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409570"
     Region          2475..2479
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409570"
     Region          2501..2506
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409570"
     Region          2514..2517
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409570"
     Region          2525..2617
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(2525,2590,2605)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(2606..2607,2609..2610)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          2646..2893
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(2646..2649,2652,2654,2667,2669,2697,2713..2716,2759,
                     2763..2764,2766,2779..2780)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..2942
                     /gene="LOC113109162"
                     /coded_by="XM_026272757.1:345..9173"
                     /db_xref="GeneID:113109162"
ORIGIN      
        1 mnsaeaaedg pndsdtdaff ktgsfrsegi kasdvlpvlr ekvafvsggr dkrggpiltf
       61 parsnhdrik qedlrrlvty lstvpsedvc krgftviidm rgskwdlikp llktlqeafp
      121 aeicvaliik pdnfwqkqkt nfgsakftfe tsmvsveglt klvdpsqlte dfegsleynh
      181 eewielrval eeflasaihl lsrledlqem lakkefpvdv egsrrlideh tqlkkkvmka
      241 pveeldhegq rllqcirssd gfsgrncisg sadfqsvvpk iaslldklhs trqhlhqmwh
      301 lrklkldqcf qlrlfeqdae kmfdwishnk elflqshtei gvsyqhamel qtqhnhfamn
      361 smnayvninr imsvasrlse aghyasqqik qistqldqew ksfaaalder stilamsavf
      421 hqkseqflsg veawckmcse gglpsemqdl elaihhhqtl yeqvtqayte vsqdgkalld
      481 vlqrplspgn sesltatany skavhcildv vhevlhhqrr lesiwqhrkv rlhqrlqlcv
      541 fqqdvqqvid wienhgeafl skhtgvgksl hraralqkrh ddfeevaqnt ytnadkllea
      601 aeqlaqtgec dpeeiykaar hlevriqdfv rrveqrklll dmsvsfhtht kelwtwmedl
      661 qkelleevcs dsvdsvqeli kqfqqqqtat leatlnvike gedlmqqlrd samssnkmph
      721 tssiahiegv lqqldeaqgh meelfherki kldiflqlri feqytievta eldawnedlv
      781 rqvnefttee pslaeqrlqr haerklamnn mtyevmqqgq dlhqyimevq asgieltgek
      841 evdlatqvqe lleflnekqh eldvsaehtq khleqcvqlr hlqaevkqvl gwirngesml
      901 dasmvnassl seaeqlqreh eqfqlaiesl fhanslqkth qsalqvqqka eillqaghfd
      961 peairscaek vavhwqqlml kmedrlklvn asvafyktse qvcsvlesle qeyrrdedwc
     1021 gahdklgssa emdhvlplis khleqkeafl kactlarrna evflkyihrn nvssqgsssn
     1081 prgpeqqvka ilnellqren rvlhfwtmkk rrldqcqqyv vfersakqal ewieeagevy
     1141 lashtspgds vektqellke yeevrvsakq tkekvkmliq ladnfvekgh thvtelkkwv
     1201 tavdkryrdf slrmgkyrcs lenalgisse dnkdleldii pasltdpevk lrdpnheine
     1261 ekrksarkke fiiaellqte kayvrdlhec letylwgmtn gveeippgia nkehiifgni
     1321 qeiydfhnni flkelinyeq lpedvghcfv twadkfniyv tycknkpdss qlilehagsf
     1381 fdeiqkrhgl tnsissylik pvqritkyql llkellscce egkgeikdgl evmlsvpkra
     1441 ndamhvsmle gfdenldvqg elflqdtfqv wdpkslirkg rdrhlflfei slvfskeikd
     1501 sagrskyiyk nklltselgv tehvegdpck falwvgrtps sdnktvlkas sievkqewik
     1561 nireviqeri ihlkgalkep irvpktpakp rnnsrrdage dadsqgdgss qpdtisiasr
     1621 tsqntvdsdk lsggceltvv lqdfmassas elsvqtgqtv ellerpserp gwclvrttdk
     1681 tplqeglvps salcishsrs svemdcffpa gkenyavsgp egktesvttl qpqaslnslh
     1741 ssspgpkrsg ntlkkwltsp vrrlshgsni kkipskqkqk rdgrksidlg ppelqddtle
     1801 ervrkvegtl sksssgmhsg geeepedesh tplpppmeii kdpsaqeekt lepgsypgfs
     1861 svnpaeqspa pprnpeleqk akalrgrmfv vnelvqtekd yvkdlgivve efmkiieekg
     1921 vpddmkgkdk ivfgnihqiy dwhkdffvge lekcledhek lpglfskher rlhmyvvycq
     1981 nkpkseyiva eydsyfeeiq kdvssrlsis dflikpiqri tkyqlllkdf lkysakagld
     2041 cqdiekavdl msqvpklcnd mmnlgrlqgf egkltsqgkl lqqetffvte qdsgvlsrsk
     2101 errvflfeqi iifsellrkg sstpgyqfkk sikvsflgle ehvendpckf vlscrgsaer
     2161 ftlqaantdv kqvwvqhitk lldlqsnfls alqspieyqk ersgsqsltr nsssggrtgq
     2221 snsrpsstvs lgaekpslsg rsptpvkltt sssgpchdry hrqfdgvgcn gtssslmvtq
     2281 dynalkenei cvtqgetvqi latnqqnmyl vyrpansqsp aaegwvpghi lgplakplid
     2341 taadsnikks lswntlrark raekdcaplk sdikvenglr kpkeilsskv tvkpkpqdsr
     2401 ssdesdyede ldpktsmell npnfiqevap efltpladvt calgetvvlc ckvcarpkpt
     2461 itlkgpdqsl lvnnnrftin iresgdivlk icnlmpqdtg iytcvavndh gtasssasik
     2521 vqgipaapar pvaqeassta vivhwlppas sgnsaissyt veyrqedslv wqksvvstad
     2581 mcvkienlip gghyqfrvsa snpwgispps epsnmvtlps tassydgtgi qwkdnfesaf
     2641 telceigrgr fsvvrkclsk askkevavkf vnkkmqkkeq vgheadilrh vqhpqlvali
     2701 dtyespmaym lvlelvedgr lldylvahde lmeekvaffi kdtlealqhl htcrvahldl
     2761 kpenllvdlh vpvpcvklsd lgdavqvssh ryvhlllgnp efaapeliqg tpvslstdvw
     2821 svgvlayvml sgvspfldes leetcvnicr ldfcfpdeyf sdisqaakdf ivstlhqdpr
     2881 krpssatclq hpwvsahsgd ysktpldtvr laafidrrkq lhdirpvtnv kglvsssmgh
     2941 tl
//
LOCUS       XP_026128543            1359 aa            linear   VRT 18-JUN-2025
DEFINITION  kalirin-like isoform X3 [Carassius auratus].
ACCESSION   XP_026128543
VERSION     XP_026128543.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272758.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1359
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1359
                     /product="kalirin-like isoform X3"
                     /calculated_mol_wt=150442
     Region          21..80
                     /region_name="SH3_Kalirin_1"
                     /note="First Src homology 3 domain of the RhoGEF kinase,
                     Kalirin; cd11852"
                     /db_xref="CDD:212786"
     Site            order(27,29,32,36,56..57,74,76..77)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212786"
     Region          78..306
                     /region_name="SH3-RhoG_link"
                     /note="SH3-RhoGEF linking unstructured region; pfam16609"
                     /db_xref="CDD:465196"
     Region          307..476
                     /region_name="RhoGEF"
                     /note="RhoGEF domain; pfam00621"
                     /db_xref="CDD:459876"
     Region          481..615
                     /region_name="PH2_Kalirin_Trio_p63RhoGEF"
                     /note="p63RhoGEF pleckstrin homology (PH) domain, repeat
                     2; cd13241"
                     /db_xref="CDD:270061"
     Site            order(490,525..526,550,552,602,605..607,609..610,612..614)
                     /site_type="other"
                     /note="Galpha i/q binding site [polypeptide binding]"
                     /db_xref="CDD:270061"
     Region          692..750
                     /region_name="SH3_Kalirin_2"
                     /note="Second Src homology 3 domain of the RhoGEF kinase,
                     Kalirin; cd11853"
                     /db_xref="CDD:212787"
     Site            order(697,699,702,706,724..725,744,746..747)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212787"
     Region          847..938
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          864..868
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409570"
     Region          892..896
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409570"
     Region          918..923
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409570"
     Region          931..934
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409570"
     Region          942..1034
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(942,1007,1022)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(1023..1024,1026..1027)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          1063..1310
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(1063..1066,1069,1071,1084,1086,1114,1130..1133,1176,
                     1180..1181,1183,1196..1197)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..1359
                     /gene="LOC113109162"
                     /coded_by="XM_026272758.1:63..4142"
                     /db_xref="GeneID:113109162"
ORIGIN      
        1 mpkwmsfklf kessrlsggc eltvvlqdfm assaselsvq tgqtveller pserpgwclv
       61 rttdktplqe glvpssalci shsrssvemd cffpagkeny avsgpegkte svttlqpqas
      121 lnslhssspg pkrsgntlkk wltspvrrls hgsnikkips kqkqkrdgrk sidlgppelq
      181 ddtleervrk vegtlsksss gmhsggeeep edeshtplpp pmeiikdpsa qeekssvlla
      241 srqssadvps aaelvsaiek lvktkmtlep gsypgfssvn paeqspappr npeleqkaka
      301 lrgrmfvvne lvqtekdyvk dlgivveefm kiieekgvpd dmkgkdkivf gnihqiydwh
      361 kdffvgelek cledheklpg lfskherrlh myvvycqnkp kseyivaeyd syfeeiqkdv
      421 ssrlsisdfl ikpiqritky qlllkdflky sakagldcqd iekavdlmsq vpklcndmmn
      481 lgrlqgfegk ltsqgkllqq etffvteqds gvlsrskerr vflfeqiiif sellrkgsst
      541 pgyqfkksik vsflgleehv endpckfvls crgsaerftl qaantdvkqv wvqhitklld
      601 lqsnflsalq spieyqkers gsqsltrnss sggrtgqsns rpsstvslga ekpslsgrsp
      661 tpvklttsss gpchdryhrq fdgvgcngts sslmvtqdyn alkeneicvt qgetvqilat
      721 nqqnmylvyr pansqspaae gwvpghilgp lakplidtaa dsnikkslsw ntlrarkrae
      781 kdcaplksdi kvenglrkpk eilsskvtvk pkpqdsrssd esdyedeldp ktsmellnpn
      841 fiqevapefl tpladvtcal getvvlcckv carpkptitl kgpdqsllvn nnrftinire
      901 sgdivlkicn lmpqdtgiyt cvavndhgta sssasikvqg ipaaparpva qeasstaviv
      961 hwlppassgn saissytvey rqedslvwqk svvstadmcv kienlipggh yqfrvsasnp
     1021 wgisppseps nmvtlpstas sydgtgiqwk dnfesaftel ceigrgrfsv vrkclskask
     1081 kevavkfvnk kmqkkeqvgh eadilrhvqh pqlvalidty espmaymlvl elvedgrlld
     1141 ylvahdelme ekvaffikdt lealqhlhtc rvahldlkpe nllvdlhvpv pcvklsdlgd
     1201 avqvsshryv hlllgnpefa apeliqgtpv slstdvwsvg vlayvmlsgv spfldeslee
     1261 tcvnicrldf cfpdeyfsdi sqaakdfivs tlhqdprkrp ssatclqhpw vsahsgdysk
     1321 tpldtvrlaa fidrrkqlhd irpvtnvkgl vsssmghtl
//
LOCUS       XP_026128544            1288 aa            linear   VRT 18-JUN-2025
DEFINITION  kalirin-like isoform X4 [Carassius auratus].
ACCESSION   XP_026128544
VERSION     XP_026128544.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272759.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1288
                     /product="kalirin-like isoform X4"
                     /calculated_mol_wt=142619
     Region          40..235
                     /region_name="SH3-RhoG_link"
                     /note="SH3-RhoGEF linking unstructured region; pfam16609"
                     /db_xref="CDD:465196"
     Region          236..405
                     /region_name="RhoGEF"
                     /note="RhoGEF domain; pfam00621"
                     /db_xref="CDD:459876"
     Region          410..544
                     /region_name="PH2_Kalirin_Trio_p63RhoGEF"
                     /note="p63RhoGEF pleckstrin homology (PH) domain, repeat
                     2; cd13241"
                     /db_xref="CDD:270061"
     Site            order(419,454..455,479,481,531,534..536,538..539,541..543)
                     /site_type="other"
                     /note="Galpha i/q binding site [polypeptide binding]"
                     /db_xref="CDD:270061"
     Region          621..679
                     /region_name="SH3_Kalirin_2"
                     /note="Second Src homology 3 domain of the RhoGEF kinase,
                     Kalirin; cd11853"
                     /db_xref="CDD:212787"
     Site            order(626,628,631,635,653..654,673,675..676)
                     /site_type="other"
                     /note="peptide ligand binding site [polypeptide binding]"
                     /db_xref="CDD:212787"
     Region          776..867
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          793..797
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409570"
     Region          821..825
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409570"
     Region          847..852
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409570"
     Region          860..863
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409570"
     Region          871..963
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(871,936,951)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(952..953,955..956)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          992..1239
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Site            order(992..995,998,1000,1013,1015,1043,1059..1062,1105,
                     1109..1110,1112,1125..1126)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270870"
     CDS             1..1288
                     /gene="LOC113109162"
                     /coded_by="XM_026272759.1:79..3945"
                     /db_xref="GeneID:113109162"
ORIGIN      
        1 mrsdkgvhpc cgwiltkccc cccqegenya vsgpegktes vttlqpqasl nslhssspgp
       61 krsgntlkkw ltspvrrlsh gsnikkipsk qkqkrdgrks idlgppelqd dtleervrkv
      121 egtlsksssg mhsggeeepe deshtplppp meiikdpsaq eekssvllas rqssadvpsa
      181 aelvsaiekl vktkmtlepg sypgfssvnp aeqspapprn peleqkakal rgrmfvvnel
      241 vqtekdyvkd lgivveefmk iieekgvpdd mkgkdkivfg nihqiydwhk dffvgelekc
      301 ledheklpgl fskherrlhm yvvycqnkpk seyivaeyds yfeeiqkdvs srlsisdfli
      361 kpiqritkyq lllkdflkys akagldcqdi ekavdlmsqv pklcndmmnl grlqgfegkl
      421 tsqgkllqqe tffvteqdsg vlsrskerrv flfeqiiifs ellrkgsstp gyqfkksikv
      481 sflgleehve ndpckfvlsc rgsaerftlq aantdvkqvw vqhitklldl qsnflsalqs
      541 pieyqkersg sqsltrnsss ggrtgqsnsr psstvslgae kpslsgrspt pvklttsssg
      601 pchdryhrqf dgvgcngtss slmvtqdyna lkeneicvtq getvqilatn qqnmylvyrp
      661 ansqspaaeg wvpghilgpl akplidtaad snikkslswn tlrarkraek dcaplksdik
      721 venglrkpke ilsskvtvkp kpqdsrssde sdyedeldpk tsmellnpnf iqevapeflt
      781 pladvtcalg etvvlcckvc arpkptitlk gpdqsllvnn nrftinires gdivlkicnl
      841 mpqdtgiytc vavndhgtas ssasikvqgi paaparpvaq easstavivh wlppassgns
      901 aissytveyr qedslvwqks vvstadmcvk ienlipgghy qfrvsasnpw gisppsepsn
      961 mvtlpstass ydgtgiqwkd nfesaftelc eigrgrfsvv rkclskaskk evavkfvnkk
     1021 mqkkeqvghe adilrhvqhp qlvalidtye spmaymlvle lvedgrlldy lvahdelmee
     1081 kvaffikdtl ealqhlhtcr vahldlkpen llvdlhvpvp cvklsdlgda vqvsshryvh
     1141 lllgnpefaa peliqgtpvs lstdvwsvgv layvmlsgvs pfldesleet cvnicrldfc
     1201 fpdeyfsdis qaakdfivst lhqdprkrps satclqhpwv sahsgdyskt pldtvrlaaf
     1261 idrrkqlhdi rpvtnvkglv sssmghtl
//
LOCUS       XP_026128545            1864 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase ubr3 isoform X1 [Carassius auratus].
ACCESSION   XP_026128545
VERSION     XP_026128545.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272760.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1864
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1864
                     /product="E3 ubiquitin-protein ligase ubr3 isoform X1"
                     /calculated_mol_wt=210570
     Region          79..150
                     /region_name="UBR-box_UBR3"
                     /note="UBR-box found in ubiquitin-protein ligase
                     E3-alpha-3 (UBR3) and similar proteins; cd19673"
                     /db_xref="CDD:439071"
     Site            order(82,98,107,110,116,132,134,146)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:439071"
     Region          1291..1343
                     /region_name="RING-H2_UBR3"
                     /note="RING finger, H2 subclass, found in
                     ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar
                     proteins; cd16483"
                     /db_xref="CDD:438146"
     Region          1409..1847
                     /region_name="PRT6_C"
                     /note="Proteolysis_6 C-terminal; pfam18995"
                     /db_xref="CDD:465944"
     CDS             1..1864
                     /gene="LOC113109163"
                     /coded_by="XM_026272760.1:1..5595"
                     /db_xref="GeneID:113109163"
ORIGIN      
        1 mmaalllrrd krstaahlka dlkrtdnssg lrqlrellds vlhpergsep ealewckwll
       61 aggdgfdefc rtvrsydnat lcglvwtanf vayrcrtcgi spcmslcaec fnngdhtghd
      121 fnmfrsqagg acdcgdgnvm resgfcsrhr lktgenvpsv prdlllmsem vlprfiitii
      181 qylrdgytep espadrdlqk vlqqldlhit fleeltkmgg amrtvltkil tnqqtfkels
      241 mgqeenvyak rnyekylsal kssglvsvee kgagagatdt pagagalgll gataaasled
      301 sskeedqdgl qgvgqrkrvk lssttkdpsi mdtlkhkcfl eellfwtiky efpqkmvtfl
      361 lnmlpdqdyk itftktfvqh yafimktlmk shesdtmsnr ivhisvqlfs neelarhvte
      421 ecqlldimvt vllymmescl ikselqdeen nrhvvvncge allknntywp lvsdfinils
      481 hqsvakrfle dqsllmlwms fvsffqgmnl nkrelnehve fesqtyyaaf aaeleacaqp
      541 mwgllthckv ketqeytktv vrycletlqm wfdaigfvde palnqltfhl plhryyamfl
      601 skgvkcqgld ldsllpdqem lmkimvhplq iqaslseihs nmwvrnglqi kgqamtyvqs
      661 hfcnsmidpd iyllqvcasr ldpdyfissv ferfkvvdll tmasqhqnav ldseqerpml
      721 egaltflvil sslrvhlgms ddeilraemv sqlcmndrth sslldlipen pnpksgvvpg
      781 scsfeemlaa vadfkapvfe pggsmqqgmy tpkaevweke fdpimvilrt vyrrdvqsam
      841 drygaflkqs gvqtgnpwpp ykertplhpc ykglvrllhc ktlhiviftl lykiwmdhqn
      901 msehvlcmvl ylielgldnq vqddkveeep cieehchdsw fpgtsllsnl hhvinfvrvr
      961 vpetapever krerereret pastssesss fgqssrrltg nwrenlreaq vfslvaerrr
     1021 kfqeiinrsn heasqavrpk ssssrslppg sppqlvteil eigesmlsll vklhqklsgk
     1081 qnslslswla eadpahhphg dgltaieril akaaarsrhs krclqeicgk vcppippkkn
     1141 spgdkksmdk eerrqrarer qqkllaefas rqksfmetam dvespetdav mdmgsaeald
     1201 sevlydcvic gqsgpstedr ptglvvllqa ssvlghrcrs dtpkrlpttd eehiypvdtc
     1261 gaahdvrltl mqryfkdssc lqsvsigwdg gvyvqtcght lhidchksym eslrndqvlq
     1321 gfsvdkgeft cplcrqfans vlpcrpgrgm etgawhtpsn ksmstlvrev edlqeqlgif
     1381 pvsaslkqrd pilaesnlsk emesvikdik nttqkkymdy gknpgspdnd flfmysvart
     1441 nlelelvhrg gnlcsggasa aakrsclnql fhvlamhmrl ysidsaynpw trltqsthnr
     1501 dteyceehpe vpmlfrdvps lliifiltmp qplrkehftc vvkvlyslqy tqalaalsvr
     1561 fsreerlaws ntgaakkntp nsdkswesll ghviseltka kdvydtssee alvlsssvws
     1621 pqsiefslqq fclpflrlsc llqhhlygds lpgclveeef sllagclgla gsaqssaacl
     1681 ewnisafdli sqwcsevial sdaptqqsvs llvqdpqwaa prllhlpdny ntifqyyhrk
     1741 fctscgktpk dpalclvcga fvclkghcck qqgvcecvlh sqhcgaatgi fllinasvii
     1801 iirghrfclw gsvyldahge edrdlrrgkp lylceeryrv leqqwvshtf dhinkrwgph
     1861 yngl
//
LOCUS       XP_026128546            1853 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase ubr3 isoform X2 [Carassius auratus].
ACCESSION   XP_026128546
VERSION     XP_026128546.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272761.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1853
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1853
                     /product="E3 ubiquitin-protein ligase ubr3 isoform X2"
                     /calculated_mol_wt=209227
     Region          79..150
                     /region_name="UBR-box_UBR3"
                     /note="UBR-box found in ubiquitin-protein ligase
                     E3-alpha-3 (UBR3) and similar proteins; cd19673"
                     /db_xref="CDD:439071"
     Site            order(82,98,107,110,116,132,134,146)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:439071"
     Region          1280..1332
                     /region_name="RING-H2_UBR3"
                     /note="RING finger, H2 subclass, found in
                     ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar
                     proteins; cd16483"
                     /db_xref="CDD:438146"
     Region          1398..1836
                     /region_name="PRT6_C"
                     /note="Proteolysis_6 C-terminal; pfam18995"
                     /db_xref="CDD:465944"
     CDS             1..1853
                     /gene="LOC113109163"
                     /coded_by="XM_026272761.1:72..5633"
                     /db_xref="GeneID:113109163"
ORIGIN      
        1 mmaalllrrd krstaahlka dlkrtdnssg lrqlrellds vlhpergsep ealewckwll
       61 aggdgfdefc rtvrsydnat lcglvwtanf vayrcrtcgi spcmslcaec fnngdhtghd
      121 fnmfrsqagg acdcgdgnvm resgfcsrhr lktgenvpsv prdlllmsem vlprfiitii
      181 qylrdgytep espadrdlqk vlqqldlhit fleeltkmgg amrtvltkil tnqqtfkels
      241 mgqeenvyak rnyekylsal kssglvsvee kgagagatdt pagagalgll gataaasled
      301 sskeedqdgl qgvgqrkrvk lssttkdpsi mdtlkhkcfl eellfwtiky efpqkmvtfl
      361 lnmlpdqdyk itftktfvqh yafimktlmk shesdtmsnr ivhisvqlfs neelarhvte
      421 ecqlldimvt vllymmescl ikselqdeen nrhvvvncge allknntywp lvsdfinils
      481 hqsvakrfle dqsllmlwms fvsffqgmnl nkrelnehve fesqtyyaaf aaeleacaqp
      541 mwgllthckv ketqeytktv vrycletlqm wfdaigfvde palnqltfhl plhryyamfl
      601 skgvkcqgld ldsllpdqem lmkimvhplq iqaslseihs nmwvrnglqi kgqamtyvqs
      661 hfcnsmidpd iyllqvcasr ldpdyfissv ferfkvvdll tmasqhqnav ldseqerpml
      721 egaltflvil sslrvhlgms ddeilraemv sqlcmndrth sslldlipen pnpksgvvpg
      781 scsfeemlaa vadfkapvfe pggsmqqgmy tpkaevweke fdpimvilrt vyrrdvqsam
      841 drygaflkqs gvqtgnpwpp ykertplhpc ykglvrllhc ktlhiviftl lykiwmdhqn
      901 msehvlcmvl ylielgldnq vqddkveeep cieehchdsw fpgtsllsnl hhvinfvrvr
      961 vpetapever krerereret pastssesss fgqnlreaqv fslvaerrrk fqeiinrsnh
     1021 easqavrpks sssrslppgs ppqlvteile igesmlsllv klhqklsgkq nslslswlae
     1081 adpahhphgd gltaierila kaaarsrhsk rclqeicgkv cppippkkns pgdkksmdke
     1141 errqrarerq qkllaefasr qksfmetamd vespetdavm dmgsaealds evlydcvicg
     1201 qsgpstedrp tglvvllqas svlghrcrsd tpkrlpttde ehiypvdtcg aahdvrltlm
     1261 qryfkdsscl qsvsigwdgg vyvqtcghtl hidchksyme slrndqvlqg fsvdkgeftc
     1321 plcrqfansv lpcrpgrgme tgawhtpsnk smstlvreve dlqeqlgifp vsaslkqrdp
     1381 ilaesnlske mesvikdikn ttqkkymdyg knpgspdndf lfmysvartn lelelvhrgg
     1441 nlcsggasaa akrsclnqlf hvlamhmrly sidsaynpwt rltqsthnrd teyceehpev
     1501 pmlfrdvpsl liifiltmpq plrkehftcv vkvlyslqyt qalaalsvrf sreerlawsn
     1561 tgaakkntpn sdkswesllg hviseltkak dvydtsseea lvlsssvwsp qsiefslqqf
     1621 clpflrlscl lqhhlygdsl pgclveeefs llagclglag saqssaacle wnisafdlis
     1681 qwcsevials daptqqsvsl lvqdpqwaap rllhlpdnyn tifqyyhrkf ctscgktpkd
     1741 palclvcgaf vclkghcckq qgvcecvlhs qhcgaatgif llinasviii irghrfclwg
     1801 svyldahgee drdlrrgkpl ylceeryrvl eqqwvshtfd hinkrwgphy ngl
//
LOCUS       XP_026128547            1852 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase ubr3 isoform X3 [Carassius auratus].
ACCESSION   XP_026128547
VERSION     XP_026128547.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272762.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1852
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1852
                     /product="E3 ubiquitin-protein ligase ubr3 isoform X3"
                     /calculated_mol_wt=209262
     Region          79..150
                     /region_name="UBR-box_UBR3"
                     /note="UBR-box found in ubiquitin-protein ligase
                     E3-alpha-3 (UBR3) and similar proteins; cd19673"
                     /db_xref="CDD:439071"
     Site            order(82,98,107,110,116,132,134,146)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:439071"
     Region          1291..1343
                     /region_name="RING-H2_UBR3"
                     /note="RING finger, H2 subclass, found in
                     ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar
                     proteins; cd16483"
                     /db_xref="CDD:438146"
     Region          1397..1835
                     /region_name="PRT6_C"
                     /note="Proteolysis_6 C-terminal; pfam18995"
                     /db_xref="CDD:465944"
     CDS             1..1852
                     /gene="LOC113109163"
                     /coded_by="XM_026272762.1:1..5559"
                     /db_xref="GeneID:113109163"
ORIGIN      
        1 mmaalllrrd krstaahlka dlkrtdnssg lrqlrellds vlhpergsep ealewckwll
       61 aggdgfdefc rtvrsydnat lcglvwtanf vayrcrtcgi spcmslcaec fnngdhtghd
      121 fnmfrsqagg acdcgdgnvm resgfcsrhr lktgenvpsv prdlllmsem vlprfiitii
      181 qylrdgytep espadrdlqk vlqqldlhit fleeltkmgg amrtvltkil tnqqtfkels
      241 mgqeenvyak rnyekylsal kssglvsvee kgagagatdt pagagalgll gataaasled
      301 sskeedqdgl qgvgqrkrvk lssttkdpsi mdtlkhkcfl eellfwtiky efpqkmvtfl
      361 lnmlpdqdyk itftktfvqh yafimktlmk shesdtmsnr ivhisvqlfs neelarhvte
      421 ecqlldimvt vllymmescl ikselqdeen nrhvvvncge allknntywp lvsdfinils
      481 hqsvakrfle dqsllmlwms fvsffqgmnl nkrelnehve fesqtyyaaf aaeleacaqp
      541 mwgllthckv ketqeytktv vrycletlqm wfdaigfvde palnqltfhl plhryyamfl
      601 skgvkcqgld ldsllpdqem lmkimvhplq iqaslseihs nmwvrnglqi kgqamtyvqs
      661 hfcnsmidpd iyllqvcasr ldpdyfissv ferfkvvdll tmasqhqnav ldseqerpml
      721 egaltflvil sslrvhlgms ddeilraemv sqlcmndrth sslldlipen pnpksgvvpg
      781 scsfeemlaa vadfkapvfe pggsmqqgmy tpkaevweke fdpimvilrt vyrrdvqsam
      841 drygaflkqs gvqtgnpwpp ykertplhpc ykglvrllhc ktlhiviftl lykiwmdhqn
      901 msehvlcmvl ylielgldnq vqddkveeep cieehchdsw fpgtsllsnl hhvinfvrvr
      961 vpetapever krerereret pastssesss fgqssrrltg nwrenlreaq vfslvaerrr
     1021 kfqeiinrsn heasqavrpk ssssrslppg sppqlvteil eigesmlsll vklhqklsgk
     1081 qnslslswla eadpahhphg dgltaieril akaaarsrhs krclqeicgk vcppippkkn
     1141 spgdkksmdk eerrqrarer qqkllaefas rqksfmetam dvespetdav mdmgsaeald
     1201 sevlydcvic gqsgpstedr ptglvvllqa ssvlghrcrs dtpkrlpttd eehiypvdtc
     1261 gaahdvrltl mqryfkdssc lqsvsigwdg gvyvqtcght lhidchksym eslrndqvlq
     1321 gfsvdkgeft cplcrqfans vlpcrpgrgm etgawhtpsn ksmstlvrev edlqeqlgif
     1381 paesnlskem esvikdiknt tqkkymdygk npgspdndfl fmysvartnl elelvhrggn
     1441 lcsggasaaa krsclnqlfh vlamhmrlys idsaynpwtr ltqsthnrdt eyceehpevp
     1501 mlfrdvpsll iifiltmpqp lrkehftcvv kvlyslqytq alaalsvrfs reerlawsnt
     1561 gaakkntpns dkswesllgh viseltkakd vydtsseeal vlsssvwspq siefslqqfc
     1621 lpflrlscll qhhlygdslp gclveeefsl lagclglags aqssaaclew nisafdlisq
     1681 wcsevialsd aptqqsvsll vqdpqwaapr llhlpdnynt ifqyyhrkfc tscgktpkdp
     1741 alclvcgafv clkghcckqq gvcecvlhsq hcgaatgifl linasviiii rghrfclwgs
     1801 vyldahgeed rdlrrgkply lceeryrvle qqwvshtfdh inkrwgphyn gl
//
LOCUS       XP_026128548            1841 aa            linear   VRT 18-JUN-2025
DEFINITION  E3 ubiquitin-protein ligase ubr3 isoform X4 [Carassius auratus].
ACCESSION   XP_026128548
VERSION     XP_026128548.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272763.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1841
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1841
                     /product="E3 ubiquitin-protein ligase ubr3 isoform X4"
                     /calculated_mol_wt=207918
     Region          79..150
                     /region_name="UBR-box_UBR3"
                     /note="UBR-box found in ubiquitin-protein ligase
                     E3-alpha-3 (UBR3) and similar proteins; cd19673"
                     /db_xref="CDD:439071"
     Site            order(82,98,107,110,116,132,134,146)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:439071"
     Region          1280..1332
                     /region_name="RING-H2_UBR3"
                     /note="RING finger, H2 subclass, found in
                     ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar
                     proteins; cd16483"
                     /db_xref="CDD:438146"
     Region          1386..1824
                     /region_name="PRT6_C"
                     /note="Proteolysis_6 C-terminal; pfam18995"
                     /db_xref="CDD:465944"
     CDS             1..1841
                     /gene="LOC113109163"
                     /coded_by="XM_026272763.1:1..5526"
                     /db_xref="GeneID:113109163"
ORIGIN      
        1 mmaalllrrd krstaahlka dlkrtdnssg lrqlrellds vlhpergsep ealewckwll
       61 aggdgfdefc rtvrsydnat lcglvwtanf vayrcrtcgi spcmslcaec fnngdhtghd
      121 fnmfrsqagg acdcgdgnvm resgfcsrhr lktgenvpsv prdlllmsem vlprfiitii
      181 qylrdgytep espadrdlqk vlqqldlhit fleeltkmgg amrtvltkil tnqqtfkels
      241 mgqeenvyak rnyekylsal kssglvsvee kgagagatdt pagagalgll gataaasled
      301 sskeedqdgl qgvgqrkrvk lssttkdpsi mdtlkhkcfl eellfwtiky efpqkmvtfl
      361 lnmlpdqdyk itftktfvqh yafimktlmk shesdtmsnr ivhisvqlfs neelarhvte
      421 ecqlldimvt vllymmescl ikselqdeen nrhvvvncge allknntywp lvsdfinils
      481 hqsvakrfle dqsllmlwms fvsffqgmnl nkrelnehve fesqtyyaaf aaeleacaqp
      541 mwgllthckv ketqeytktv vrycletlqm wfdaigfvde palnqltfhl plhryyamfl
      601 skgvkcqgld ldsllpdqem lmkimvhplq iqaslseihs nmwvrnglqi kgqamtyvqs
      661 hfcnsmidpd iyllqvcasr ldpdyfissv ferfkvvdll tmasqhqnav ldseqerpml
      721 egaltflvil sslrvhlgms ddeilraemv sqlcmndrth sslldlipen pnpksgvvpg
      781 scsfeemlaa vadfkapvfe pggsmqqgmy tpkaevweke fdpimvilrt vyrrdvqsam
      841 drygaflkqs gvqtgnpwpp ykertplhpc ykglvrllhc ktlhiviftl lykiwmdhqn
      901 msehvlcmvl ylielgldnq vqddkveeep cieehchdsw fpgtsllsnl hhvinfvrvr
      961 vpetapever krerereret pastssesss fgqnlreaqv fslvaerrrk fqeiinrsnh
     1021 easqavrpks sssrslppgs ppqlvteile igesmlsllv klhqklsgkq nslslswlae
     1081 adpahhphgd gltaierila kaaarsrhsk rclqeicgkv cppippkkns pgdkksmdke
     1141 errqrarerq qkllaefasr qksfmetamd vespetdavm dmgsaealds evlydcvicg
     1201 qsgpstedrp tglvvllqas svlghrcrsd tpkrlpttde ehiypvdtcg aahdvrltlm
     1261 qryfkdsscl qsvsigwdgg vyvqtcghtl hidchksyme slrndqvlqg fsvdkgeftc
     1321 plcrqfansv lpcrpgrgme tgawhtpsnk smstlvreve dlqeqlgifp aesnlskeme
     1381 svikdikntt qkkymdygkn pgspdndflf mysvartnle lelvhrggnl csggasaaak
     1441 rsclnqlfhv lamhmrlysi dsaynpwtrl tqsthnrdte yceehpevpm lfrdvpslli
     1501 ifiltmpqpl rkehftcvvk vlyslqytqa laalsvrfsr eerlawsntg aakkntpnsd
     1561 kswesllghv iseltkakdv ydtsseealv lsssvwspqs iefslqqfcl pflrlscllq
     1621 hhlygdslpg clveeefsll agclglagsa qssaaclewn isafdlisqw csevialsda
     1681 ptqqsvsllv qdpqwaaprl lhlpdnynti fqyyhrkfct scgktpkdpa lclvcgafvc
     1741 lkghcckqqg vcecvlhsqh cgaatgifll inasviiiir ghrfclwgsv yldahgeedr
     1801 dlrrgkplyl ceeryrvleq qwvshtfdhi nkrwgphyng l
//
LOCUS       XP_026128549            1042 aa            linear   VRT 18-JUN-2025
DEFINITION  kinesin heavy chain isoform X1 [Carassius auratus].
ACCESSION   XP_026128549
VERSION     XP_026128549.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272764.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1042
                     /product="kinesin heavy chain isoform X1"
                     /calculated_mol_wt=118328
     Region          7..327
                     /region_name="KISc_KHC_KIF5"
                     /note="Kinesin motor domain, kinesin heavy chain (KHC) or
                     KIF5-like subgroup; cd01369"
                     /db_xref="CDD:276820"
     Site            order(17,86,89,91..94,232)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276820"
     Site            order(157..159,162,276,280..281)
                     /site_type="other"
                     /note="beta tubulin interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:276820"
     Site            order(158..160,162,238..240,249,253,257,276,281)
                     /site_type="other"
                     /note="microtubule interaction site [polypeptide binding]"
                     /db_xref="CDD:276820"
     Site            order(236,238..239,253,256..257,260)
                     /site_type="other"
                     /note="alpha tubulin interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:276820"
     Region          488..>923
                     /region_name="SMC_N"
                     /note="RecF/RecN/SMC N terminal domain; cl47134"
                     /db_xref="CDD:481474"
     Region          852..921
                     /region_name="Khc_CBD_cc"
                     /note="cargo binding coiled-coil domain found in kinesin
                     heavy chains; cd23649"
                     /db_xref="CDD:467880"
     CDS             1..1042
                     /gene="LOC113109164"
                     /coded_by="XM_026272764.1:190..3318"
                     /db_xref="GeneID:113109164"
ORIGIN      
        1 mtdavaecni kvlcrfrpln qaeilrgdkf lptfqgddtv iiggkpyvfd rvfptnttqe
       61 qvyntcakqi vkdvlggyng tifaygqtss gkthtmegkl hdpqqmgiip riaedifnhi
      121 famdenlefh ikvsyfeiym ekirdlldvt ktnlsvhedk nrvpyvkgct erfvsspeev
      181 mdvidegksn rhvavtnmne hssrshsifl inikqehvet eqklcgklyl vdlagsekvs
      241 ktgaagavld eakninksls slgnvisala egtkthvpyr dskmtrilqd slggncrttm
      301 ficcspssyn daetkstlmf gqraktiknt asinleltae qwkrkyekek ekskslrdti
      361 qrlelellrw rsgeplhcsd esrekvpete qadadvvkld gsdetsldne rssvrqrere
      421 rdsdsssivv riseeerqky eeeirklyrq lddkddeinl qcqlaeklke qildqdella
      481 strgdsdkvq telgrlqmes esakaevrev lqaleelavn ydqksqevee knlhnkqlae
      541 qlslkmaslm eleaelaqmq evssqqrkri advlnglmkd lsefssivgn geiklpveis
      601 gaieeeftva rlyiskikse vksmvkrcrq lenmqlechr kmeetsrels scqllvsqhe
      661 akirslteym qnvehkkrql edsydalsee ffmlqnsesh vaevdggeka dreaggkksg
      721 grpslhaesr qtqlshlrde inekqrlidd ltdknqalel elahvrssls nlkmqddtks
      781 acleklsfqq erneqskqdl krleetvare lqtlhnlrkl fvqdlttrvk kstetgpdds
      841 ggsntqkqki sflennldql tkvhkqlvrd nadlrcelpk lekrlrstae rvraletalk
      901 dakqgamndr rryqqeveri rdamrlrypp rrsntaliak pvrpghpvaa tsptsfcstr
      961 askpatsysn tvflqedkpa pqktntvgys tvrsmdimss cpldvengnt tdindnrsdv
     1021 hcgsmvddes riymmqqgta as
//
LOCUS       XP_026128550            1042 aa            linear   VRT 18-JUN-2025
DEFINITION  kinesin heavy chain isoform X1 [Carassius auratus].
ACCESSION   XP_026128550
VERSION     XP_026128550.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272765.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1042
                     /product="kinesin heavy chain isoform X1"
                     /calculated_mol_wt=118328
     Region          7..327
                     /region_name="KISc_KHC_KIF5"
                     /note="Kinesin motor domain, kinesin heavy chain (KHC) or
                     KIF5-like subgroup; cd01369"
                     /db_xref="CDD:276820"
     Site            order(17,86,89,91..94,232)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276820"
     Site            order(157..159,162,276,280..281)
                     /site_type="other"
                     /note="beta tubulin interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:276820"
     Site            order(158..160,162,238..240,249,253,257,276,281)
                     /site_type="other"
                     /note="microtubule interaction site [polypeptide binding]"
                     /db_xref="CDD:276820"
     Site            order(236,238..239,253,256..257,260)
                     /site_type="other"
                     /note="alpha tubulin interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:276820"
     Region          488..>923
                     /region_name="SMC_N"
                     /note="RecF/RecN/SMC N terminal domain; cl47134"
                     /db_xref="CDD:481474"
     Region          852..921
                     /region_name="Khc_CBD_cc"
                     /note="cargo binding coiled-coil domain found in kinesin
                     heavy chains; cd23649"
                     /db_xref="CDD:467880"
     CDS             1..1042
                     /gene="LOC113109164"
                     /coded_by="XM_026272765.1:190..3318"
                     /db_xref="GeneID:113109164"
ORIGIN      
        1 mtdavaecni kvlcrfrpln qaeilrgdkf lptfqgddtv iiggkpyvfd rvfptnttqe
       61 qvyntcakqi vkdvlggyng tifaygqtss gkthtmegkl hdpqqmgiip riaedifnhi
      121 famdenlefh ikvsyfeiym ekirdlldvt ktnlsvhedk nrvpyvkgct erfvsspeev
      181 mdvidegksn rhvavtnmne hssrshsifl inikqehvet eqklcgklyl vdlagsekvs
      241 ktgaagavld eakninksls slgnvisala egtkthvpyr dskmtrilqd slggncrttm
      301 ficcspssyn daetkstlmf gqraktiknt asinleltae qwkrkyekek ekskslrdti
      361 qrlelellrw rsgeplhcsd esrekvpete qadadvvkld gsdetsldne rssvrqrere
      421 rdsdsssivv riseeerqky eeeirklyrq lddkddeinl qcqlaeklke qildqdella
      481 strgdsdkvq telgrlqmes esakaevrev lqaleelavn ydqksqevee knlhnkqlae
      541 qlslkmaslm eleaelaqmq evssqqrkri advlnglmkd lsefssivgn geiklpveis
      601 gaieeeftva rlyiskikse vksmvkrcrq lenmqlechr kmeetsrels scqllvsqhe
      661 akirslteym qnvehkkrql edsydalsee ffmlqnsesh vaevdggeka dreaggkksg
      721 grpslhaesr qtqlshlrde inekqrlidd ltdknqalel elahvrssls nlkmqddtks
      781 acleklsfqq erneqskqdl krleetvare lqtlhnlrkl fvqdlttrvk kstetgpdds
      841 ggsntqkqki sflennldql tkvhkqlvrd nadlrcelpk lekrlrstae rvraletalk
      901 dakqgamndr rryqqeveri rdamrlrypp rrsntaliak pvrpghpvaa tsptsfcstr
      961 askpatsysn tvflqedkpa pqktntvgys tvrsmdimss cpldvengnt tdindnrsdv
     1021 hcgsmvddes riymmqqgta as
//
LOCUS       XP_026128551            1032 aa            linear   VRT 18-JUN-2025
DEFINITION  kinesin heavy chain isoform X2 [Carassius auratus].
ACCESSION   XP_026128551
VERSION     XP_026128551.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272766.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1032
                     /product="kinesin heavy chain isoform X2"
                     /calculated_mol_wt=117173
     Region          7..327
                     /region_name="KISc_KHC_KIF5"
                     /note="Kinesin motor domain, kinesin heavy chain (KHC) or
                     KIF5-like subgroup; cd01369"
                     /db_xref="CDD:276820"
     Site            order(17,86,89,91..94,232)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:276820"
     Site            order(157..159,162,276,280..281)
                     /site_type="other"
                     /note="beta tubulin interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:276820"
     Site            order(158..160,162,238..240,249,253,257,276,281)
                     /site_type="other"
                     /note="microtubule interaction site [polypeptide binding]"
                     /db_xref="CDD:276820"
     Site            order(236,238..239,253,256..257,260)
                     /site_type="other"
                     /note="alpha tubulin interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:276820"
     Region          <335..>562
                     /region_name="Smc"
                     /note="Chromosome segregation ATPase Smc [Cell cycle
                     control, cell division, chromosome partitioning]; COG1196"
                     /db_xref="CDD:440809"
     Region          478..>913
                     /region_name="SMC_N"
                     /note="RecF/RecN/SMC N terminal domain; cl47134"
                     /db_xref="CDD:481474"
     Region          842..911
                     /region_name="Khc_CBD_cc"
                     /note="cargo binding coiled-coil domain found in kinesin
                     heavy chains; cd23649"
                     /db_xref="CDD:467880"
     CDS             1..1032
                     /gene="LOC113109164"
                     /coded_by="XM_026272766.1:1..3099"
                     /db_xref="GeneID:113109164"
ORIGIN      
        1 mtdavaecni kvlcrfrpln qaeilrgdkf lptfqgddtv iiggkpyvfd rvfptnttqe
       61 qvyntcakqi vkdvlggyng tifaygqtss gkthtmegkl hdpqqmgiip riaedifnhi
      121 famdenlefh ikvsyfeiym ekirdlldvt ktnlsvhedk nrvpyvkgct erfvsspeev
      181 mdvidegksn rhvavtnmne hssrshsifl inikqehvet eqklcgklyl vdlagsekvs
      241 ktgaagavld eakninksls slgnvisala egtkthvpyr dskmtrilqd slggncrttm
      301 ficcspssyn daetkstlmf gqraktiknt asinleltae qwkrkyekek ekskslrdti
      361 qrlelellrw rsgekvpete qadadvvkld gsdetsldne rssvrqrere rdsdsssivv
      421 riseeerqky eeeirklyrq lddkddeinl qcqlaeklke qildqdella strgdsdkvq
      481 telgrlqmes esakaevrev lqaleelavn ydqksqevee knlhnkqlae qlslkmaslm
      541 eleaelaqmq evssqqrkri advlnglmkd lsefssivgn geiklpveis gaieeeftva
      601 rlyiskikse vksmvkrcrq lenmqlechr kmeetsrels scqllvsqhe akirslteym
      661 qnvehkkrql edsydalsee ffmlqnsesh vaevdggeka dreaggkksg grpslhaesr
      721 qtqlshlrde inekqrlidd ltdknqalel elahvrssls nlkmqddtks acleklsfqq
      781 erneqskqdl krleetvare lqtlhnlrkl fvqdlttrvk kstetgpdds ggsntqkqki
      841 sflennldql tkvhkqlvrd nadlrcelpk lekrlrstae rvraletalk dakqgamndr
      901 rryqqeveri rdamrlrypp rrsntaliak pvrpghpvaa tsptsfcstr askpatsysn
      961 tvflqedkpa pqktntvgys tvrsmdimss cpldvengnt tdindnrsdv hcgsmvddes
     1021 riymmqqgta as
//
LOCUS       XP_026128552            1133 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128552
VERSION     XP_026128552.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272767.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1133
                     /product="plakophilin-4-like isoform X1"
                     /calculated_mol_wt=125981
     Region          484..>697
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          486..511
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(502,506,510,544,548,552,589,593,597)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          515..554
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          519..555
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          559..600
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          563..598
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          606..656
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          664..705
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          780..810
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          803..>923
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          820..855
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          822..854
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(845,849,853,890,894,898,937,941)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          861..901
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          903..948
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          907..943
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1133
                     /gene="LOC113109166"
                     /coded_by="XM_026272767.1:16..3417"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 maceaqipas advtrpecgv wqwihelrqk ntsspraliw kqsgwiklvl remfvgleql
       61 fsrlvwmccv ltggmpalks sagsqeaavt spnstatnil asvkeqelqf erltreleve
      121 rqivanqler crlssdspga asggssetsl pwrsagstqm nsysdsgyqd avsyysgpaq
      181 rlqtslpasg gsstlqrgsr aegqaaghpr tqelqgsgmm dgtkpgramr rvgsmparvq
      241 plyrssvsps rgslrttgss ygspittepr alftsatqka spsprssctt spysgavgsv
      301 redqhavpqh ygsmmsrtfl hdvsnpyith syeiyeridp rpdnftgvra sytsqhsqmg
      361 adlrsaaspd ryigpiyedr tfqrplyhsl sqtaadlnhs pqsplyrspf gmsnlqrsss
      421 qrsnmmyqrn nyalntiyte ayqstpywsp dpsytrqpmd ddatrspsid smqkdprefa
      481 wrdpdlqevi hmlqhqfpsv qanaaaylqh lcykdnhvkt evcrlggikh lvdlldhkvl
      541 evqryacgal rnlvygratd dnkiavknag gvpallrllr ttvdtevrel vtgvlwnlss
      601 cdavkmtivr dalssvtntv iiphsgwssa dyhhehklkl hssvvlrnss gclrnlssag
      661 eearkymrsc eglvdsllyv ikacvstsdf dskivencvc ilrnlsyrle leispsglta
      721 nqeldgvmgs esprkekens cwgrkkrkkk nipeeqwdgv gpipgfsksp kgaemlwhps
      781 vvkpyltlla essnpatleg sagslqnlsa ghwkfaayir aavrkekglp ilvellrmdn
      841 drvvcsiata lrnmaldvrn keligkyamr dlvnrlpggn ttqlsddtva aicctlhevs
      901 rrnmenakal adaggieklv nitkgrgesr ysvkvvkaaa qvlntlwqyr dlrtiykkdg
      961 wnqnhfltpv stlererfrs apalpsstlq mtpahhtgst lsspimhsdh pktqnkqvyn
     1021 yqgengiskn rtigsakasq cysslsregs rreqkayrtd etghrnhety rtylhpplah
     1081 edsylenmvh yspadysqth gfrntsnyad fysstrrplh hsehyqgspd swv
//
LOCUS       XP_026128553            1119 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128553
VERSION     XP_026128553.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272768.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1119
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1119
                     /product="plakophilin-4-like isoform X2"
                     /calculated_mol_wt=124203
     Region          470..>683
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          472..497
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(488,492,496,530,534,538,575,579,583)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          501..540
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          505..541
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          545..586
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          549..584
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          592..642
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          650..691
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          766..796
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          789..>909
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          806..841
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          808..840
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(831,835,839,876,880,884,923,927)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          847..887
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          889..934
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          893..929
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1119
                     /gene="LOC113109166"
                     /coded_by="XM_026272768.1:465..3824"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mtafrrnass evkrrltgsc cditeqhchq ypgfcqrtdv cwvgaalqsl vwmccvltgg
       61 mpalkssags qeaavtspns tatnilasvk eqelqferlt releverqiv anqlercrls
      121 sdspgaasgg ssetslpwrs agstqmnsys dsgyqdavsy ysgpaqrlqt slpasggsst
      181 lqrgsraegq aaghprtqel qgsgmmdgtk pgramrrvgs mparvqplyr ssvspsrgsl
      241 rttgssygsp ittepralft satqkaspsp rsscttspys gavgsvredq havpqhygsm
      301 msrtflhdvs npyithsyei yeridprpdn ftgvrasyts qhsqmgadlr saaspdryig
      361 piyedrtfqr plyhslsqta adlnhspqsp lyrspfgmsn lqrsssqrsn mmyqrnnyal
      421 ntiyteayqs tpywspdpsy trqpmdddat rspsidsmqk dprefawrdp dlqevihmlq
      481 hqfpsvqana aaylqhlcyk dnhvktevcr lggikhlvdl ldhkvlevqr yacgalrnlv
      541 ygratddnki avknaggvpa llrllrttvd tevrelvtgv lwnlsscdav kmtivrdals
      601 svtntviiph sgwssadyhh ehklklhssv vlrnssgclr nlssageear kymrsceglv
      661 dsllyvikac vstsdfdski vencvcilrn lsyrleleis psgltanqel dgvmgsespr
      721 kekenscwgr kkrkkknipe eqwdgvgpip gfskspkgae mlwhpsvvkp yltllaessn
      781 patlegsags lqnlsaghwk faayiraavr kekglpilve llrmdndrvv csiatalrnm
      841 aldvrnkeli gkyamrdlvn rlpggnttql sddtvaaicc tlhevsrrnm enakaladag
      901 gieklvnitk grgesrysvk vvkaaaqvln tlwqyrdlrt iykkdgwnqn hfltpvstle
      961 rerfrsapal psstlqmtpa hhtgstlssp imhsdhpktq nkqvynyqge ngisknrtig
     1021 sakasqcyss lsregsrreq kayrtdetgh rnhetyrtyl hpplahedsy lenmvhyspa
     1081 dysqthgfrn tsnyadfyss trrplhhseh yqgspdswv
//
LOCUS       XP_026128555            1114 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X3 [Carassius auratus].
ACCESSION   XP_026128555
VERSION     XP_026128555.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272770.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1114
                     /product="plakophilin-4-like isoform X3"
                     /calculated_mol_wt=123724
     Region          465..>678
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          467..492
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(483,487,491,525,529,533,570,574,578)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          496..535
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          500..536
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          540..581
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          544..579
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          587..637
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          645..686
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          761..791
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          784..>904
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          801..836
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          803..835
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(826,830,834,871,875,879,918,922)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          842..882
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          884..929
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          888..924
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1114
                     /gene="LOC113109166"
                     /coded_by="XM_026272770.1:16..3360"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 maceaqipas advtrpecgv wqwihelrqk ntsspraliw kqsgwiklvl retggmpalk
       61 ssagsqeaav tspnstatni lasvkeqelq ferltrelev erqivanqle rcrlssdspg
      121 aasggssets lpwrsagstq mnsysdsgyq davsyysgpa qrlqtslpas ggsstlqrgs
      181 raegqaaghp rtqelqgsgm mdgtkpgram rrvgsmparv qplyrssvsp srgslrttgs
      241 sygspittep ralftsatqk aspsprssct tspysgavgs vredqhavpq hygsmmsrtf
      301 lhdvsnpyit hsyeiyerid prpdnftgvr asytsqhsqm gadlrsaasp dryigpiyed
      361 rtfqrplyhs lsqtaadlnh spqsplyrsp fgmsnlqrss sqrsnmmyqr nnyalntiyt
      421 eayqstpyws pdpsytrqpm dddatrspsi dsmqkdpref awrdpdlqev ihmlqhqfps
      481 vqanaaaylq hlcykdnhvk tevcrlggik hlvdlldhkv levqryacga lrnlvygrat
      541 ddnkiavkna ggvpallrll rttvdtevre lvtgvlwnls scdavkmtiv rdalssvtnt
      601 viiphsgwss adyhhehklk lhssvvlrns sgclrnlssa geearkymrs ceglvdslly
      661 vikacvstsd fdskivencv cilrnlsyrl eleispsglt anqeldgvmg sesprkeken
      721 scwgrkkrkk knipeeqwdg vgpipgfsks pkgaemlwhp svvkpyltll aessnpatle
      781 gsagslqnls aghwkfaayi raavrkekgl pilvellrmd ndrvvcsiat alrnmaldvr
      841 nkeligkyam rdlvnrlpgg nttqlsddtv aaicctlhev srrnmenaka ladaggiekl
      901 vnitkgrges rysvkvvkaa aqvlntlwqy rdlrtiykkd gwnqnhfltp vstlererfr
      961 sapalpsstl qmtpahhtgs tlsspimhsd hpktqnkqvy nyqgengisk nrtigsakas
     1021 qcysslsreg srreqkayrt detghrnhet yrtylhppla hedsylenmv hyspadysqt
     1081 hgfrntsnya dfysstrrpl hhsehyqgsp dswv
//
LOCUS       XP_026128556            1104 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X4 [Carassius auratus].
ACCESSION   XP_026128556
VERSION     XP_026128556.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272771.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1104
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1104
                     /product="plakophilin-4-like isoform X4"
                     /calculated_mol_wt=122569
     Region          455..>668
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          457..482
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(473,477,481,515,519,523,560,564,568)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          486..525
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          490..526
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          530..571
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          534..569
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          577..627
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          635..676
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          751..781
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          774..>894
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          791..826
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          793..825
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(816,820,824,861,865,869,908,912)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          832..872
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          874..919
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          878..914
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1104
                     /gene="LOC113109166"
                     /coded_by="XM_026272771.1:16..3330"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 maceaqipas advtrpecgv wqwihelrqk ntsspraliw kqsgwiklvl remfvgleql
       61 fsrlvwmccv ltggmpalks sagsqeaavt spnstatnil asvkeqelqf erltreleve
      121 rqivanqler crlssdspga asggssetsl pwrsagstqm nsysdsgyqd avsyysgpaq
      181 rlqtslpasg gsstlqrgsr aegqaaghpr tqelqgsgmm dgtkpgramr rvgsmparvq
      241 plyrssvsps rgslrttgss ygspittepr alftsatqka spsprssctt spysgavgsv
      301 redqhavpqh ygsmmsrtfl hdvsnpyith syeiyeridp rpdnftgvra sytsqhsqmg
      361 adlrsaaspd ryigpiyedr tfqrplyhsl sqtaadlnhs pqsplyrspf eayqstpyws
      421 pdpsytrqpm dddatrspsi dsmqkdpref awrdpdlqev ihmlqhqfps vqanaaaylq
      481 hlcykdnhvk tevcrlggik hlvdlldhkv levqryacga lrnlvygrat ddnkiavkna
      541 ggvpallrll rttvdtevre lvtgvlwnls scdavkmtiv rdalssvtnt viiphsgwss
      601 adyhhehklk lhssvvlrns sgclrnlssa geearkymrs ceglvdslly vikacvstsd
      661 fdskivencv cilrnlsyrl eleispsglt anqeldgvmg sesprkeken scwgrkkrkk
      721 knipeeqwdg vgpipgfsks pkgaemlwhp svvkpyltll aessnpatle gsagslqnls
      781 aghwkfaayi raavrkekgl pilvellrmd ndrvvcsiat alrnmaldvr nkeligkyam
      841 rdlvnrlpgg nttqlsddtv aaicctlhev srrnmenaka ladaggiekl vnitkgrges
      901 rysvkvvkaa aqvlntlwqy rdlrtiykkd gwnqnhfltp vstlererfr sapalpsstl
      961 qmtpahhtgs tlsspimhsd hpktqnkqvy nyqgengisk nrtigsakas qcysslsreg
     1021 srreqkayrt detghrnhet yrtylhppla hedsylenmv hyspadysqt hgfrntsnya
     1081 dfysstrrpl hhsehyqgsp dswv
//
LOCUS       XP_026128557            1099 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X5 [Carassius auratus].
ACCESSION   XP_026128557
VERSION     XP_026128557.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272772.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1099
                     /product="plakophilin-4-like isoform X5"
                     /calculated_mol_wt=122023
     Region          450..>663
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          452..477
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(468,472,476,510,514,518,555,559,563)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          481..520
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          485..521
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          525..566
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          529..564
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          572..622
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          630..671
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          746..776
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          769..>889
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          786..821
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          788..820
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(811,815,819,856,860,864,903,907)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          827..867
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          869..914
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          873..909
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1099
                     /gene="LOC113109166"
                     /coded_by="XM_026272772.1:465..3764"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mtafrrnass evkrrltgsc cditeqhchq ypgfcqrtgg mpalkssags qeaavtspns
       61 tatnilasvk eqelqferlt releverqiv anqlercrls sdspgaasgg ssetslpwrs
      121 agstqmnsys dsgyqdavsy ysgpaqrlqt slpasggsst lqrgsraegq aaghprtqel
      181 qgsgmmdgtk pgramrrvgs mparvqplyr ssvspsrgsl rttgssygsp ittepralft
      241 satqkaspsp rsscttspys gavgsvredq havpqhygsm msrtflhdvs npyithsyei
      301 yeridprpdn ftgvrasyts qhsqmgadlr saaspdryig piyedrtfqr plyhslsqta
      361 adlnhspqsp lyrspfgmsn lqrsssqrsn mmyqrnnyal ntiyteayqs tpywspdpsy
      421 trqpmdddat rspsidsmqk dprefawrdp dlqevihmlq hqfpsvqana aaylqhlcyk
      481 dnhvktevcr lggikhlvdl ldhkvlevqr yacgalrnlv ygratddnki avknaggvpa
      541 llrllrttvd tevrelvtgv lwnlsscdav kmtivrdals svtntviiph sgwssadyhh
      601 ehklklhssv vlrnssgclr nlssageear kymrsceglv dsllyvikac vstsdfdski
      661 vencvcilrn lsyrleleis psgltanqel dgvmgsespr kekenscwgr kkrkkknipe
      721 eqwdgvgpip gfskspkgae mlwhpsvvkp yltllaessn patlegsags lqnlsaghwk
      781 faayiraavr kekglpilve llrmdndrvv csiatalrnm aldvrnkeli gkyamrdlvn
      841 rlpggnttql sddtvaaicc tlhevsrrnm enakaladag gieklvnitk grgesrysvk
      901 vvkaaaqvln tlwqyrdlrt iykkdgwnqn hfltpvstle rerfrsapal psstlqmtpa
      961 hhtgstlssp imhsdhpktq nkqvynyqge ngisknrtig sakasqcyss lsregsrreq
     1021 kayrtdetgh rnhetyrtyl hpplahedsy lenmvhyspa dysqthgfrn tsnyadfyss
     1081 trrplhhseh yqgspdswv
//
LOCUS       XP_026128558            1079 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X6 [Carassius auratus].
ACCESSION   XP_026128558
VERSION     XP_026128558.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272773.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1079
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1079
                     /product="plakophilin-4-like isoform X6"
                     /calculated_mol_wt=120337
     Region          430..>643
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          432..457
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(448,452,456,490,494,498,535,539,543)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          461..500
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          465..501
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          505..546
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          509..544
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          552..602
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          610..651
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          726..756
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          749..>869
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          766..801
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          768..800
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(791,795,799,836,840,844,883,887)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          807..847
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          849..894
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          853..889
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1079
                     /gene="LOC113109166"
                     /coded_by="XM_026272773.1:16..3255"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 maceaqipas advtrpecgv wqwihelrqk ntsspraliw kqsgwiklvl reelqferlt
       61 releverqiv anqlercrls sdspgaasgg ssetslpwrs agstqmnsys dsgyqdavsy
      121 ysgpaqrlqt slpasggsst lqrgsraegq aaghprtqel qgsgmmdgtk pgramrrvgs
      181 mparvqplyr ssvspsrgsl rttgssygsp ittepralft satqkaspsp rsscttspys
      241 gavgsvredq havpqhygsm msrtflhdvs npyithsyei yeridprpdn ftgvrasyts
      301 qhsqmgadlr saaspdryig piyedrtfqr plyhslsqta adlnhspqsp lyrspfgmsn
      361 lqrsssqrsn mmyqrnnyal ntiyteayqs tpywspdpsy trqpmdddat rspsidsmqk
      421 dprefawrdp dlqevihmlq hqfpsvqana aaylqhlcyk dnhvktevcr lggikhlvdl
      481 ldhkvlevqr yacgalrnlv ygratddnki avknaggvpa llrllrttvd tevrelvtgv
      541 lwnlsscdav kmtivrdals svtntviiph sgwssadyhh ehklklhssv vlrnssgclr
      601 nlssageear kymrsceglv dsllyvikac vstsdfdski vencvcilrn lsyrleleis
      661 psgltanqel dgvmgsespr kekenscwgr kkrkkknipe eqwdgvgpip gfskspkgae
      721 mlwhpsvvkp yltllaessn patlegsags lqnlsaghwk faayiraavr kekglpilve
      781 llrmdndrvv csiatalrnm aldvrnkeli gkyamrdlvn rlpggnttql sddtvaaicc
      841 tlhevsrrnm enakaladag gieklvnitk grgesrysvk vvkaaaqvln tlwqyrdlrt
      901 iykkdgwnqn hfltpvstle rerfrsapal psstlqmtpa hhtgstlssp imhsdhpktq
      961 nkqvynyqge ngisknrtig sakasqcyss lsregsrreq kayrtdetgh rnhetyrtyl
     1021 hpplahedsy lenmvhyspa dysqthgfrn tsnyadfyss trrplhhseh yqgspdswv
//
LOCUS       XP_026128559            1059 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X7 [Carassius auratus].
ACCESSION   XP_026128559
VERSION     XP_026128559.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272774.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1059
                     /product="plakophilin-4-like isoform X7"
                     /calculated_mol_wt=117508
     Region          410..>623
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          412..437
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(428,432,436,470,474,478,515,519,523)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          441..480
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          445..481
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          485..526
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          489..524
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          532..582
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          590..631
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          706..736
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          729..>849
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          746..781
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..780
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(771,775,779,816,820,824,863,867)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          787..827
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          829..874
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          833..869
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1059
                     /gene="LOC113109166"
                     /coded_by="XM_026272774.1:477..3656"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mpalkssags qeaavtspns tatnilasvk eqelqferlt releverqiv anqlercrls
       61 sdspgaasgg ssetslpwrs agstqmnsys dsgyqdavsy ysgpaqrlqt slpasggsst
      121 lqrgsraegq aaghprtqel qgsgmmdgtk pgramrrvgs mparvqplyr ssvspsrgsl
      181 rttgssygsp ittepralft satqkaspsp rsscttspys gavgsvredq havpqhygsm
      241 msrtflhdvs npyithsyei yeridprpdn ftgvrasyts qhsqmgadlr saaspdryig
      301 piyedrtfqr plyhslsqta adlnhspqsp lyrspfgmsn lqrsssqrsn mmyqrnnyal
      361 ntiyteayqs tpywspdpsy trqpmdddat rspsidsmqk dprefawrdp dlqevihmlq
      421 hqfpsvqana aaylqhlcyk dnhvktevcr lggikhlvdl ldhkvlevqr yacgalrnlv
      481 ygratddnki avknaggvpa llrllrttvd tevrelvtgv lwnlsscdav kmtivrdals
      541 svtntviiph sgwssadyhh ehklklhssv vlrnssgclr nlssageear kymrsceglv
      601 dsllyvikac vstsdfdski vencvcilrn lsyrleleis psgltanqel dgvmgsespr
      661 kekenscwgr kkrkkknipe eqwdgvgpip gfskspkgae mlwhpsvvkp yltllaessn
      721 patlegsags lqnlsaghwk faayiraavr kekglpilve llrmdndrvv csiatalrnm
      781 aldvrnkeli gkyamrdlvn rlpggnttql sddtvaaicc tlhevsrrnm enakaladag
      841 gieklvnitk grgesrysvk vvkaaaqvln tlwqyrdlrt iykkdgwnqn hfltpvstle
      901 rerfrsapal psstlqmtpa hhtgstlssp imhsdhpktq nkqvynyqge ngisknrtig
      961 sakasqcyss lsregsrreq kayrtdetgh rnhetyrtyl hpplahedsy lenmvhyspa
     1021 dysqthgfrn tsnyadfyss trrplhhseh yqgspdswv
//
LOCUS       XP_026128560            1059 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X8 [Carassius auratus].
ACCESSION   XP_026128560
VERSION     XP_026128560.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272775.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1059
                     /product="plakophilin-4-like isoform X8"
                     /calculated_mol_wt=117508
     Region          410..>623
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          412..437
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(428,432,436,470,474,478,515,519,523)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          441..480
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          445..481
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          485..526
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          489..524
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          532..582
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          590..631
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          706..736
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          729..>849
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          746..781
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..780
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(771,775,779,816,820,824,863,867)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          787..827
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          829..874
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          833..869
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1059
                     /gene="LOC113109166"
                     /coded_by="XM_026272775.1:484..3663"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mpalkssags qeaavtspns tatnilasvk eqelqferlt releverqiv anqlercrls
       61 sdspgaasgg ssetslpwrs agstqmnsys dsgyqdavsy ysgpaqrlqt slpasggsst
      121 lqrgsraegq aaghprtqel qgsgmmdgtk pgramrrvgs mparvqplyr ssvspsrgsl
      181 rttgssygsp ittepralft satqkaspsp rsscttspys gavgsvredq havpqhygsm
      241 msrtflhdvs npyithsyei yeridprpdn ftgvrasyts qhsqmgadlr saaspdryig
      301 piyedrtfqr plyhslsqta adlnhspqsp lyrspfgmsn lqrsssqrsn mmyqrnnyal
      361 ntiyteayqs tpywspdpsy trqpmdddat rspsidsmqk dprefawrdp dlqevihmlq
      421 hqfpsvqana aaylqhlcyk dnhvktevcr lggikhlvdl ldhkvlevqr yacgalrnlv
      481 ygratddnki avknaggvpa llrllrttvd tevrelvtgv lwnlsscdav kmtivrdals
      541 svtntviiph sgwssadyhh ehklklhssv vlrnssgclr nlssageear kymrsceglv
      601 dsllyvikac vstsdfdski vencvcilrn lsyrleleis psgltanqel dgvmgsespr
      661 kekenscwgr kkrkkknipe eqwdgvgpip gfskspkgae mlwhpsvvkp yltllaessn
      721 patlegsags lqnlsaghwk faayiraavr kekglpilve llrmdndrvv csiatalrnm
      781 aldvrnkeli gkyamrdlvn rlpggnttql sddtvaaicc tlhevsrrnm enakaladag
      841 gieklvnitk grgesrysvk vvkaaaqvln tlwqyrdlrt iykkdgwnqn hfltpvstle
      901 rerfrsapal psstlqmtpa hhtgstlssp imhsdhpktq nkqvynyqge ngisknrtig
      961 sakasqcyss lsregsrreq kayrtdetgh rnhetyrtyl hpplahedsy lenmvhyspa
     1021 dysqthgfrn tsnyadfyss trrplhhseh yqgspdswv
//
LOCUS       XP_026128561            1059 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X8 [Carassius auratus].
ACCESSION   XP_026128561
VERSION     XP_026128561.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272776.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1059
                     /product="plakophilin-4-like isoform X8"
                     /calculated_mol_wt=117508
     Region          410..>623
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          412..437
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(428,432,436,470,474,478,515,519,523)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          441..480
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          445..481
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          485..526
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          489..524
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          532..582
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          590..631
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          706..736
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          729..>849
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          746..781
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..780
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(771,775,779,816,820,824,863,867)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          787..827
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          829..874
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          833..869
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1059
                     /gene="LOC113109166"
                     /coded_by="XM_026272776.1:119..3298"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mpalkssags qeaavtspns tatnilasvk eqelqferlt releverqiv anqlercrls
       61 sdspgaasgg ssetslpwrs agstqmnsys dsgyqdavsy ysgpaqrlqt slpasggsst
      121 lqrgsraegq aaghprtqel qgsgmmdgtk pgramrrvgs mparvqplyr ssvspsrgsl
      181 rttgssygsp ittepralft satqkaspsp rsscttspys gavgsvredq havpqhygsm
      241 msrtflhdvs npyithsyei yeridprpdn ftgvrasyts qhsqmgadlr saaspdryig
      301 piyedrtfqr plyhslsqta adlnhspqsp lyrspfgmsn lqrsssqrsn mmyqrnnyal
      361 ntiyteayqs tpywspdpsy trqpmdddat rspsidsmqk dprefawrdp dlqevihmlq
      421 hqfpsvqana aaylqhlcyk dnhvktevcr lggikhlvdl ldhkvlevqr yacgalrnlv
      481 ygratddnki avknaggvpa llrllrttvd tevrelvtgv lwnlsscdav kmtivrdals
      541 svtntviiph sgwssadyhh ehklklhssv vlrnssgclr nlssageear kymrsceglv
      601 dsllyvikac vstsdfdski vencvcilrn lsyrleleis psgltanqel dgvmgsespr
      661 kekenscwgr kkrkkknipe eqwdgvgpip gfskspkgae mlwhpsvvkp yltllaessn
      721 patlegsags lqnlsaghwk faayiraavr kekglpilve llrmdndrvv csiatalrnm
      781 aldvrnkeli gkyamrdlvn rlpggnttql sddtvaaicc tlhevsrrnm enakaladag
      841 gieklvnitk grgesrysvk vvkaaaqvln tlwqyrdlrt iykkdgwnqn hfltpvstle
      901 rerfrsapal psstlqmtpa hhtgstlssp imhsdhpktq nkqvynyqge ngisknrtig
      961 sakasqcyss lsregsrreq kayrtdetgh rnhetyrtyl hpplahedsy lenmvhyspa
     1021 dysqthgfrn tsnyadfyss trrplhhseh yqgspdswv
//
LOCUS       XP_026128562            1059 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X7 [Carassius auratus].
ACCESSION   XP_026128562
VERSION     XP_026128562.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272777.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1059
                     /product="plakophilin-4-like isoform X7"
                     /calculated_mol_wt=117508
     Region          410..>623
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          412..437
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(428,432,436,470,474,478,515,519,523)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          441..480
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          445..481
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          485..526
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          489..524
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          532..582
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          590..631
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          706..736
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          729..>849
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          746..781
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..780
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(771,775,779,816,820,824,863,867)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          787..827
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          829..874
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          833..869
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1059
                     /gene="LOC113109166"
                     /coded_by="XM_026272777.1:207..3386"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mpalkssags qeaavtspns tatnilasvk eqelqferlt releverqiv anqlercrls
       61 sdspgaasgg ssetslpwrs agstqmnsys dsgyqdavsy ysgpaqrlqt slpasggsst
      121 lqrgsraegq aaghprtqel qgsgmmdgtk pgramrrvgs mparvqplyr ssvspsrgsl
      181 rttgssygsp ittepralft satqkaspsp rsscttspys gavgsvredq havpqhygsm
      241 msrtflhdvs npyithsyei yeridprpdn ftgvrasyts qhsqmgadlr saaspdryig
      301 piyedrtfqr plyhslsqta adlnhspqsp lyrspfgmsn lqrsssqrsn mmyqrnnyal
      361 ntiyteayqs tpywspdpsy trqpmdddat rspsidsmqk dprefawrdp dlqevihmlq
      421 hqfpsvqana aaylqhlcyk dnhvktevcr lggikhlvdl ldhkvlevqr yacgalrnlv
      481 ygratddnki avknaggvpa llrllrttvd tevrelvtgv lwnlsscdav kmtivrdals
      541 svtntviiph sgwssadyhh ehklklhssv vlrnssgclr nlssageear kymrsceglv
      601 dsllyvikac vstsdfdski vencvcilrn lsyrleleis psgltanqel dgvmgsespr
      661 kekenscwgr kkrkkknipe eqwdgvgpip gfskspkgae mlwhpsvvkp yltllaessn
      721 patlegsags lqnlsaghwk faayiraavr kekglpilve llrmdndrvv csiatalrnm
      781 aldvrnkeli gkyamrdlvn rlpggnttql sddtvaaicc tlhevsrrnm enakaladag
      841 gieklvnitk grgesrysvk vvkaaaqvln tlwqyrdlrt iykkdgwnqn hfltpvstle
      901 rerfrsapal psstlqmtpa hhtgstlssp imhsdhpktq nkqvynyqge ngisknrtig
      961 sakasqcyss lsregsrreq kayrtdetgh rnhetyrtyl hpplahedsy lenmvhyspa
     1021 dysqthgfrn tsnyadfyss trrplhhseh yqgspdswv
//
LOCUS       XP_026128563            1059 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X8 [Carassius auratus].
ACCESSION   XP_026128563
VERSION     XP_026128563.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272778.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1059
                     /product="plakophilin-4-like isoform X8"
                     /calculated_mol_wt=117508
     Region          410..>623
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          412..437
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(428,432,436,470,474,478,515,519,523)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          441..480
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          445..481
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          485..526
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          489..524
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          532..582
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          590..631
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          706..736
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          729..>849
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          746..781
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..780
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(771,775,779,816,820,824,863,867)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          787..827
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          829..874
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          833..869
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..1059
                     /gene="LOC113109166"
                     /coded_by="XM_026272778.1:229..3408"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mpalkssags qeaavtspns tatnilasvk eqelqferlt releverqiv anqlercrls
       61 sdspgaasgg ssetslpwrs agstqmnsys dsgyqdavsy ysgpaqrlqt slpasggsst
      121 lqrgsraegq aaghprtqel qgsgmmdgtk pgramrrvgs mparvqplyr ssvspsrgsl
      181 rttgssygsp ittepralft satqkaspsp rsscttspys gavgsvredq havpqhygsm
      241 msrtflhdvs npyithsyei yeridprpdn ftgvrasyts qhsqmgadlr saaspdryig
      301 piyedrtfqr plyhslsqta adlnhspqsp lyrspfgmsn lqrsssqrsn mmyqrnnyal
      361 ntiyteayqs tpywspdpsy trqpmdddat rspsidsmqk dprefawrdp dlqevihmlq
      421 hqfpsvqana aaylqhlcyk dnhvktevcr lggikhlvdl ldhkvlevqr yacgalrnlv
      481 ygratddnki avknaggvpa llrllrttvd tevrelvtgv lwnlsscdav kmtivrdals
      541 svtntviiph sgwssadyhh ehklklhssv vlrnssgclr nlssageear kymrsceglv
      601 dsllyvikac vstsdfdski vencvcilrn lsyrleleis psgltanqel dgvmgsespr
      661 kekenscwgr kkrkkknipe eqwdgvgpip gfskspkgae mlwhpsvvkp yltllaessn
      721 patlegsags lqnlsaghwk faayiraavr kekglpilve llrmdndrvv csiatalrnm
      781 aldvrnkeli gkyamrdlvn rlpggnttql sddtvaaicc tlhevsrrnm enakaladag
      841 gieklvnitk grgesrysvk vvkaaaqvln tlwqyrdlrt iykkdgwnqn hfltpvstle
      901 rerfrsapal psstlqmtpa hhtgstlssp imhsdhpktq nkqvynyqge ngisknrtig
      961 sakasqcyss lsregsrreq kayrtdetgh rnhetyrtyl hpplahedsy lenmvhyspa
     1021 dysqthgfrn tsnyadfyss trrplhhseh yqgspdswv
//
LOCUS       XP_026128564             974 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X9 [Carassius auratus].
ACCESSION   XP_026128564
VERSION     XP_026128564.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272779.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..974
                     /product="plakophilin-4-like isoform X9"
                     /calculated_mol_wt=108533
     Region          325..>538
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          327..352
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(343,347,351,385,389,393,430,434,438)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          356..395
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          360..396
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          400..441
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          404..439
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          447..497
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          505..546
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          621..651
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          644..>764
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          661..696
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          663..695
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(686,690,694,731,735,739,778,782)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          702..742
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          744..789
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..784
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..974
                     /gene="LOC113109166"
                     /coded_by="XM_026272779.1:183..3107"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mnsysdsgyq davsyysgpa qrlqtslpas ggsstlqrgs raegqaaghp rtqelqgsgm
       61 mdgtkpgram rrvgsmparv qplyrssvsp srgslrttgs sygspittep ralftsatqk
      121 aspsprssct tspysgavgs vredqhavpq hygsmmsrtf lhdvsnpyit hsyeiyerid
      181 prpdnftgvr asytsqhsqm gadlrsaasp dryigpiyed rtfqrplyhs lsqtaadlnh
      241 spqsplyrsp fgmsnlqrss sqrsnmmyqr nnyalntiyt eayqstpyws pdpsytrqpm
      301 dddatrspsi dsmqkdpref awrdpdlqev ihmlqhqfps vqanaaaylq hlcykdnhvk
      361 tevcrlggik hlvdlldhkv levqryacga lrnlvygrat ddnkiavkna ggvpallrll
      421 rttvdtevre lvtgvlwnls scdavkmtiv rdalssvtnt viiphsgwss adyhhehklk
      481 lhssvvlrns sgclrnlssa geearkymrs ceglvdslly vikacvstsd fdskivencv
      541 cilrnlsyrl eleispsglt anqeldgvmg sesprkeken scwgrkkrkk knipeeqwdg
      601 vgpipgfsks pkgaemlwhp svvkpyltll aessnpatle gsagslqnls aghwkfaayi
      661 raavrkekgl pilvellrmd ndrvvcsiat alrnmaldvr nkeligkyam rdlvnrlpgg
      721 nttqlsddtv aaicctlhev srrnmenaka ladaggiekl vnitkgrges rysvkvvkaa
      781 aqvlntlwqy rdlrtiykkd gwnqnhfltp vstlererfr sapalpsstl qmtpahhtgs
      841 tlsspimhsd hpktqnkqvy nyqgengisk nrtigsakas qcysslsreg srreqkayrt
      901 detghrnhet yrtylhppla hedsylenmv hyspadysqt hgfrntsnya dfysstrrpl
      961 hhsehyqgsp dswv
//
LOCUS       XP_026128565             974 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X9 [Carassius auratus].
ACCESSION   XP_026128565
VERSION     XP_026128565.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272780.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..974
                     /product="plakophilin-4-like isoform X9"
                     /calculated_mol_wt=108533
     Region          325..>538
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          327..352
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(343,347,351,385,389,393,430,434,438)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          356..395
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          360..396
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          400..441
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          404..439
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          447..497
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          505..546
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          621..651
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          644..>764
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          661..696
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          663..695
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(686,690,694,731,735,739,778,782)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          702..742
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          744..789
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..784
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..974
                     /gene="LOC113109166"
                     /coded_by="XM_026272780.1:370..3294"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mnsysdsgyq davsyysgpa qrlqtslpas ggsstlqrgs raegqaaghp rtqelqgsgm
       61 mdgtkpgram rrvgsmparv qplyrssvsp srgslrttgs sygspittep ralftsatqk
      121 aspsprssct tspysgavgs vredqhavpq hygsmmsrtf lhdvsnpyit hsyeiyerid
      181 prpdnftgvr asytsqhsqm gadlrsaasp dryigpiyed rtfqrplyhs lsqtaadlnh
      241 spqsplyrsp fgmsnlqrss sqrsnmmyqr nnyalntiyt eayqstpyws pdpsytrqpm
      301 dddatrspsi dsmqkdpref awrdpdlqev ihmlqhqfps vqanaaaylq hlcykdnhvk
      361 tevcrlggik hlvdlldhkv levqryacga lrnlvygrat ddnkiavkna ggvpallrll
      421 rttvdtevre lvtgvlwnls scdavkmtiv rdalssvtnt viiphsgwss adyhhehklk
      481 lhssvvlrns sgclrnlssa geearkymrs ceglvdslly vikacvstsd fdskivencv
      541 cilrnlsyrl eleispsglt anqeldgvmg sesprkeken scwgrkkrkk knipeeqwdg
      601 vgpipgfsks pkgaemlwhp svvkpyltll aessnpatle gsagslqnls aghwkfaayi
      661 raavrkekgl pilvellrmd ndrvvcsiat alrnmaldvr nkeligkyam rdlvnrlpgg
      721 nttqlsddtv aaicctlhev srrnmenaka ladaggiekl vnitkgrges rysvkvvkaa
      781 aqvlntlwqy rdlrtiykkd gwnqnhfltp vstlererfr sapalpsstl qmtpahhtgs
      841 tlsspimhsd hpktqnkqvy nyqgengisk nrtigsakas qcysslsreg srreqkayrt
      901 detghrnhet yrtylhppla hedsylenmv hyspadysqt hgfrntsnya dfysstrrpl
      961 hhsehyqgsp dswv
//
LOCUS       XP_026128566             974 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X9 [Carassius auratus].
ACCESSION   XP_026128566
VERSION     XP_026128566.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272781.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..974
                     /product="plakophilin-4-like isoform X9"
                     /calculated_mol_wt=108533
     Region          325..>538
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          327..352
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(343,347,351,385,389,393,430,434,438)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          356..395
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          360..396
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          400..441
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          404..439
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          447..497
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          505..546
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          621..651
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          644..>764
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          661..696
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          663..695
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(686,690,694,731,735,739,778,782)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          702..742
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          744..789
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..784
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..974
                     /gene="LOC113109166"
                     /coded_by="XM_026272781.1:288..3212"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mnsysdsgyq davsyysgpa qrlqtslpas ggsstlqrgs raegqaaghp rtqelqgsgm
       61 mdgtkpgram rrvgsmparv qplyrssvsp srgslrttgs sygspittep ralftsatqk
      121 aspsprssct tspysgavgs vredqhavpq hygsmmsrtf lhdvsnpyit hsyeiyerid
      181 prpdnftgvr asytsqhsqm gadlrsaasp dryigpiyed rtfqrplyhs lsqtaadlnh
      241 spqsplyrsp fgmsnlqrss sqrsnmmyqr nnyalntiyt eayqstpyws pdpsytrqpm
      301 dddatrspsi dsmqkdpref awrdpdlqev ihmlqhqfps vqanaaaylq hlcykdnhvk
      361 tevcrlggik hlvdlldhkv levqryacga lrnlvygrat ddnkiavkna ggvpallrll
      421 rttvdtevre lvtgvlwnls scdavkmtiv rdalssvtnt viiphsgwss adyhhehklk
      481 lhssvvlrns sgclrnlssa geearkymrs ceglvdslly vikacvstsd fdskivencv
      541 cilrnlsyrl eleispsglt anqeldgvmg sesprkeken scwgrkkrkk knipeeqwdg
      601 vgpipgfsks pkgaemlwhp svvkpyltll aessnpatle gsagslqnls aghwkfaayi
      661 raavrkekgl pilvellrmd ndrvvcsiat alrnmaldvr nkeligkyam rdlvnrlpgg
      721 nttqlsddtv aaicctlhev srrnmenaka ladaggiekl vnitkgrges rysvkvvkaa
      781 aqvlntlwqy rdlrtiykkd gwnqnhfltp vstlererfr sapalpsstl qmtpahhtgs
      841 tlsspimhsd hpktqnkqvy nyqgengisk nrtigsakas qcysslsreg srreqkayrt
      901 detghrnhet yrtylhppla hedsylenmv hyspadysqt hgfrntsnya dfysstrrpl
      961 hhsehyqgsp dswv
//
LOCUS       XP_026128567             974 aa            linear   VRT 18-JUN-2025
DEFINITION  plakophilin-4-like isoform X9 [Carassius auratus].
ACCESSION   XP_026128567
VERSION     XP_026128567.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272782.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..974
                     /product="plakophilin-4-like isoform X9"
                     /calculated_mol_wt=108533
     Region          325..>538
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          327..352
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(343,347,351,385,389,393,430,434,438)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          356..395
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          360..396
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          400..441
                     /region_name="Arm"
                     /note="Armadillo/beta-catenin-like repeat; pfam00514"
                     /db_xref="CDD:425727"
     Region          404..439
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          447..497
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          505..546
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          621..651
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          644..>764
                     /region_name="PLN03200"
                     /note="cellulose synthase-interactive protein;
                     Provisional"
                     /db_xref="CDD:215629"
     Region          661..696
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          663..695
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Site            order(686,690,694,731,735,739,778,782)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:293788"
     Region          702..742
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     Region          744..789
                     /region_name="ARM"
                     /note="Armadillo/beta-catenin-like repeats; smart00185"
                     /db_xref="CDD:214547"
     Region          748..784
                     /region_name="armadillo repeat"
                     /note="armadillo repeat [structural motif]"
                     /db_xref="CDD:293788"
     CDS             1..974
                     /gene="LOC113109166"
                     /coded_by="XM_026272782.1:275..3199"
                     /db_xref="GeneID:113109166"
ORIGIN      
        1 mnsysdsgyq davsyysgpa qrlqtslpas ggsstlqrgs raegqaaghp rtqelqgsgm
       61 mdgtkpgram rrvgsmparv qplyrssvsp srgslrttgs sygspittep ralftsatqk
      121 aspsprssct tspysgavgs vredqhavpq hygsmmsrtf lhdvsnpyit hsyeiyerid
      181 prpdnftgvr asytsqhsqm gadlrsaasp dryigpiyed rtfqrplyhs lsqtaadlnh
      241 spqsplyrsp fgmsnlqrss sqrsnmmyqr nnyalntiyt eayqstpyws pdpsytrqpm
      301 dddatrspsi dsmqkdpref awrdpdlqev ihmlqhqfps vqanaaaylq hlcykdnhvk
      361 tevcrlggik hlvdlldhkv levqryacga lrnlvygrat ddnkiavkna ggvpallrll
      421 rttvdtevre lvtgvlwnls scdavkmtiv rdalssvtnt viiphsgwss adyhhehklk
      481 lhssvvlrns sgclrnlssa geearkymrs ceglvdslly vikacvstsd fdskivencv
      541 cilrnlsyrl eleispsglt anqeldgvmg sesprkeken scwgrkkrkk knipeeqwdg
      601 vgpipgfsks pkgaemlwhp svvkpyltll aessnpatle gsagslqnls aghwkfaayi
      661 raavrkekgl pilvellrmd ndrvvcsiat alrnmaldvr nkeligkyam rdlvnrlpgg
      721 nttqlsddtv aaicctlhev srrnmenaka ladaggiekl vnitkgrges rysvkvvkaa
      781 aqvlntlwqy rdlrtiykkd gwnqnhfltp vstlererfr sapalpsstl qmtpahhtgs
      841 tlsspimhsd hpktqnkqvy nyqgengisk nrtigsakas qcysslsreg srreqkayrt
      901 detghrnhet yrtylhppla hedsylenmv hyspadysqt hgfrntsnya dfysstrrpl
      961 hhsehyqgsp dswv
//
LOCUS       XP_026128568             353 aa            linear   VRT 18-JUN-2025
DEFINITION  cytokine receptor family member b4 [Carassius auratus].
ACCESSION   XP_026128568
VERSION     XP_026128568.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272783.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..353
                     /product="cytokine receptor family member b4"
                     /calculated_mol_wt=40211
     Region          3..104
                     /region_name="Tissue_fac"
                     /note="Tissue factor; pfam01108"
                     /db_xref="CDD:460067"
     Region          116..212
                     /region_name="Interfer-bind"
                     /note="Interferon-alpha/beta receptor, fibronectin type
                     III; pfam09294"
                     /db_xref="CDD:462746"
     CDS             1..353
                     /gene="crfb4"
                     /coded_by="XM_026272783.1:193..1254"
                     /db_xref="GeneID:113109168"
ORIGIN      
        1 msasscvsrl vlfyifcvta eripapenvr risvnmglvl ewdppqnttn tllnytaemq
       61 gwsnyepvcr sssalscdft dkvsifgsyh lrvraelhge ssdwvetenf sldkiteisa
      121 phvelrsrkg qtevditdpp mkkknlrhvf gnisyrirfw kdgetkkeel ireqnrvvlp
      181 kleplvkycv eveilyltnk sltsnitclt ntssnevesw liavvllgsf lvvlfavvli
      241 flavwfgyrg criifpdtdl pedlkkflsq qlqssvlwam qestpvkehc celrilhkep
      301 isspdnqqie gplrihtykn ecctganvkq sseeksqmil ateqepllae mrp
//
LOCUS       XP_026128570             462 aa            linear   VRT 18-JUN-2025
DEFINITION  cytokine receptor family member b2 [Carassius auratus].
ACCESSION   XP_026128570
VERSION     XP_026128570.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272785.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..462
                     /product="cytokine receptor family member b2"
                     /calculated_mol_wt=50489
     Region          21..106
                     /region_name="Tissue_fac"
                     /note="Tissue factor; pfam01108"
                     /db_xref="CDD:460067"
     Region          119..212
                     /region_name="Interfer-bind"
                     /note="Interferon-alpha/beta receptor, fibronectin type
                     III; cl46366"
                     /db_xref="CDD:480706"
     CDS             1..462
                     /gene="crfb2"
                     /coded_by="XM_026272785.1:477..1865"
                     /db_xref="GeneID:113109169"
ORIGIN      
        1 mfviariltt ialfhlgccm dlpapvklnl ssqyfvhvls wemgpgspdg vhykvsvhal
       61 eggtvavkqc ekvtfplrcn lteafsnved iyyvsvtavl gnrtspssdl npfrpiqnti
      121 ldtplltvta cnqwlcinlk apaenlhkvy dsfwfhyllt itsedgrefi mkteglknvt
      181 ikdlapgrry cvnvsivdss ppnrpavcas ipkranvsda visvvlcllm llivmcaprf
      241 fprcfclkpd lppvlssfqs gnkvlhvtav esfnklcegr nsmdkikins eedeeeeeae
      301 aqaqylntrg splcvypvts rsvsllnqtp dtslasstda qtanlivfeg shshpeptas
      361 prlptgasal qnvpsvfpth venedpessa dvnlfsvmlg gvsdkaepvk ddvqesgaqr
      421 llqacapssw isdslcqnse skvnileeee edddnsgyls rn
//
LOCUS       XP_074416032             540 aa            linear   VRT 18-JUN-2025
DEFINITION  LOW QUALITY PROTEIN: interleukin-10 receptor subunit beta
            [Carassius auratus].
ACCESSION   XP_074416032
VERSION     XP_074416032.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_074559931.1
KEYWORDS    RefSeq; corrected model.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            frameshifts :: corrected 1 indel
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..540
                     /product="LOW QUALITY PROTEIN: interleukin-10 receptor
                     subunit beta"
                     /calculated_mol_wt=60033
     CDS             1..540
                     /gene="LOC113109170"
                     /coded_by="XM_074559931.1:729..2351"
                     /note="The sequence of the model RefSeq protein was
                     modified relative to its source genomic sequence to
                     represent the inferred CDS: inserted 2 bases in 1 codon"
                     /db_xref="GeneID:113109170"
ORIGIN      
        1 mrttytwqyl lmclcftvlh tipapvnfti lshnfkhilk wspginsppq tvfnlnescs
       61 egkkpppqrl qqsirkmtvd vsetfeniyt hctfflwast dnmtspvvnk sispyedtii
      121 gppiiflsgc gnclkisisl pseskkvdql hpfydsvsfn iswkkagqne anhistsskh
      181 hvlqnlkpgn qycvkvlpvi nmnhntqpsa wqcqytskee prgmlyvigw slgvavaglg
      241 vlgltlslvy tgsickpktl lpkimdnnik ailipeqtls esvsvtelql isasknhptk
      301 nnkplnaekd peskqiedee syvnkadted eeedegkcny mdcvtlnsgw etnnceekai
      361 vsiltshnss gichkkdiam eqihhefdsk kllvldmsad rsshledkna elelkgsqes
      421 sadvsgninl fsvtlralgp evdldeeevg seelspshis llkrqktnlq lyaptqkekk
      481 tddpmqvesq dllflcssdl dvsteddtls gymlthtgnm heqnsstsxg tdcdtdfmsr
//
LOCUS       XP_026128571             180 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M2-like [Carassius auratus].
ACCESSION   XP_026128571
VERSION     XP_026128571.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272786.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 1% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..180
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..180
                     /product="gamma-crystallin M2-like"
                     /calculated_mol_wt=22227
     Region          9..88
                     /region_name="XTALbg"
                     /note="Beta/gamma crystallins; smart00247"
                     /db_xref="CDD:214583"
     Region          96..175
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..180
                     /gene="LOC113109171"
                     /coded_by="XM_026272786.1:1..543"
                     /db_xref="GeneID:113109171"
ORIGIN      
        1 mhviiltfqv ifyedrnfqg rsyecmsdcg dfssymsrch scrvesgcwm mydrpnymgn
       61 qyffrrgeya dymsmfgmne cirscrmipm yrgsyrmriy erenfmgqmy emmddcdsim
      121 dryrmshcqs chvmdghwlf yeqphyrgrm wyfrpgeyrs fsnmggmrfm smrrimdswy
//
LOCUS       XP_026128572            1740 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109172 [Carassius auratus].
ACCESSION   XP_026128572
VERSION     XP_026128572.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272787.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1740
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1740
                     /product="uncharacterized protein LOC113109172"
                     /calculated_mol_wt=199031
     Region          79..>198
                     /region_name="DUF1759"
                     /note="Protein of unknown function (DUF1759); pfam03564"
                     /db_xref="CDD:281552"
     Region          735..956
                     /region_name="RT_pepA17"
                     /note="Reverse transcriptase (RTs) in retrotransposons.
                     This subfamily represents the RT domain of a
                     multifunctional enzyme. C-terminal to the RT domain is a
                     domain homologous to aspartic proteinases (corresponding
                     to Merops family A17) encoded by...; cd01644"
                     /db_xref="CDD:238822"
     Site            order(797..802,839..840,876,878..879,947..948)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:238822"
     Site            order(797..802,839,878)
                     /site_type="other"
                     /note="putative NTP binding site [chemical binding]"
                     /db_xref="CDD:238822"
     Site            840
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:238822"
     Region          970..1133
                     /region_name="Peptidase_A17"
                     /note="Pao retrotransposon peptidase; pfam05380"
                     /db_xref="CDD:461634"
     Region          1442..1519
                     /region_name="rve"
                     /note="Integrase core domain; pfam00665"
                     /db_xref="CDD:459897"
     Region          1630..1734
                     /region_name="DUF5641"
                     /note="Family of unknown function (DUF5641); pfam18701"
                     /db_xref="CDD:465838"
     CDS             1..1740
                     /gene="LOC113109172"
                     /coded_by="XM_026272787.1:1877..7099"
                     /db_xref="GeneID:113109172"
ORIGIN      
        1 mqvyeqneds keetrellrd casvrkkhvp klsssvlqsi plqegatksy qeastadlvk
       61 vlaesisssr lpipepatfy gdslrfsdwk isfqtlidrk nipvneklyy lrkyvegpan
      121 kaiesyfllg tesayqaawg vleerygnpf viakafrdkl nswpkigskd svelreftdf
      181 lrgceaamsq ikgleilndc nenqkilskl pdwlasawnr qvieieeetk tfptfsrfvk
      241 fltreakiac npvtslhalk pneigkgkis rnqdtrakvl tvqsrekvda vkctfcerlg
      301 hsihkcrkfm eknvaervkf vqmnklcfgc lnpghhsknc edrsvcekcq kkhpsclhed
      361 rikeakrtpq sgqskeklke rnpelvqnkd tvsevtsnrv iqdvnnthts tivpvwvsat
      421 depthevlvy alldtqsdtt fileeiaqal dtkkesvqlk lstmvskstv vpcqkiiglk
      481 vrgfysekis lpvtysrefi panrthiptp ktarvwphlm hiaekiapkq vcdiglligy
      541 ncpqallpre ivsgkenqpf aqrtdlgwsi vgcgnssvdy gdaigvshri ivkqvlpslq
      601 sslnltskvq yicrtqikev itppnvikal esdfnekaav dscisqedlr flskmetgir
      661 hkedghyemp lpfkedrpnl pnnkgcaihr lkslekrlkr dekyyrdyld fmnetiargd
      721 aekvpaeetd kipawyiphh gvyhpqkpek irvvfdcsak fqgsslndhl ltgpeltntl
      781 vgvlcrfrkg pvaimcdier mfhqfhvkee dqdylrflww ekgdleskpq vyrmkvhlfg
      841 aasspgcany glkhiaaqgr gyfsessirf iernfyvddg ltsvstvdea iklmkearel
      901 cstgklclhk fvssseevka sipleecaks vmehdlalge lhmeralgvk wciksdsfqf
      961 rvfvkeqplt rrgilstvas vydplgfaap lilvgkqilq qmcqdkvgwd eplkeelltk
     1021 wkawltdlrn ladvkiqrcy lpstfkevqr yelhhfsdas tsgygectyl raisisgdvh
     1081 cslvmakarv asskvttipr lelsaavvav qtsdllrkel dianleeyfw tdskvvlgyi
     1141 nndakrfhif vanriqrikq stdtkqwryv tskenpadha srgltseeli ssnwftgprf
     1201 lwkdelpsdv kvgeiidndp elrkaqvhkt qakeerslld rlqkfsdwtr lvkaiarlkr
     1261 csrevkglss rvneatsiee rqdaeitvir mvqqsafcde iqrlrqqkei esstnklhrl
     1321 npfldehgil rvggrlvhaa lhphvkhpai lprhshistl lirhyheqvy dqgrgmtine
     1381 lrsngfwilg cskavssyiy kctrcrklrr cteeqrmanl pqermettpp ftycgmdcfg
     1441 pfyvkdgrke lrrygllltc mcsraihvem lddlstdafi nalcafiair gpvrqlrsdq
     1501 gtnfvgarre faealkeinq erlkefgcef imntpsashm ggiwerqirt irsvltsild
     1561 qsaqrldsas lrtflyevma ivnsrpltte hlndpsgpqp ltpnhiltmk tsiilpppge
     1621 fvkedlylhk rwrkvqylan efwsrwkkey llnlqhrqkw hkhrrnvkvn divilkddta
     1681 prsrwklakv tevhsgtdgc vrtvkllisd stldkkgkrv tkptylerpi qkivtpiead
//
LOCUS       XP_026128573            1075 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 12-like isoform X1
            [Carassius auratus].
ACCESSION   XP_026128573
VERSION     XP_026128573.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272788.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1075
                     /product="NACHT, LRR and PYD domains-containing protein
                     12-like isoform X1"
                     /calculated_mol_wt=122065
     Region          253..324
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          339..506
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          588..648
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          650..779
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          763..1073
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Site            order(764,766,769,771,783,787,789,792,794,813,816,818,821,
                     823,841,843,846,848,867,870,872,875,877,896,899,901,904,
                     906,925,928,930,933,935,954,957,959,962,964,983,986,988,
                     991,993,1012,1015,1017,1020,1022,1041,1044,1046,1049,1051,
                     1070,1073)
                     /site_type="active"
                     /note="Leucine-rich repeats [active]"
                     /db_xref="CDD:238064"
     Site            order(790..791,845,903,932,990,1016,1018,1045)
                     /site_type="other"
                     /note="Substrate binding site [chemical binding]"
                     /db_xref="CDD:238064"
     Region          867..895
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          896..924
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          925..953
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          954..982
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          983..1011
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          1012..1036
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..1075
                     /gene="LOC113109173"
                     /coded_by="XM_026272788.1:395..3622"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lssvhqkrse aesscvsvrs dasmdrpihf ksgdtntdlr icsqrssspd
      181 hscvslksdg smgrppalsd eavtsdpsra dgersisggv ssvfclnnts vtaslnkhdq
      241 avndelqrvk eqhktsmknk yerlceglkl qenesllnsi ytqlyiiege regvneehev
      301 lqmektartq hsqdapiycn difkasaeag seekeqiktv ltkgiagigk tvsvqkfild
      361 waegkanqdv dfmfvlpfre lnlirdhqys lhtllldfhp elqdldsqiy eeckvvfifd
      421 gldesritlm fsdaqkvcdv tetssvavlm sklmkgellp saliwitsrp aaanqipsey
      481 ihrlteiqgf tepqkeeyfr krisdehqas riishirrar slhimchipv fcwisstvlq
      541 klleedlrae ipqtltemyi hflliqinmr kqkyeerdpe kllpsdrevi vklaevafkq
      601 lmegnvmfye edliesgvdv tdasvysgic teifkqesvi hqrkvysfih lsvqeflaaf
      661 ylfycyltkn kktlrefrly rsvkvslydl ltsavdkale skngrldlfl rfllgvsles
      721 nqrllqdllt htenssetis rttryikdki kssdhlsadq sinlflclle vkdqtlfrei
      781 qefvksdkhs ekklspahcs tisymiqmse epldeldpkk yntsaegrrr lipavnncrk
      841 avlrycdvtd egcsalasal rsnpshlrel dlswntirdl gvkhlcavle dprckleklw
      901 ltdcdvtdeg csaltsalrs npshlrelsl swnkirdlgv krlcagledp rckleklwlk
      961 dcdvtdegcs altsalrsnp shlreldlsw nkirdsgvkr lcagledphc kletlwlsdc
     1021 gvtdegcsal asalrsnpsh lrelnltlnk lrpsevklls dlkddprykl etlhy
//
LOCUS       XP_026128574             907 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X2
            [Carassius auratus].
ACCESSION   XP_026128574
VERSION     XP_026128574.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272789.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..907
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X2"
                     /calculated_mol_wt=102952
     Region          253..323
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          334..501
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          578..638
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          640..780
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          689..>907
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     CDS             1..907
                     /gene="LOC113109173"
                     /coded_by="XM_026272789.1:395..3118"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lrlfhqkrse aesscvsvrs dwsmdppvhf ksgdtktdlr lfhqkrseae
      181 sscvsvrsdw smdppvhfks gdtktdlssv dqkrseaess cvsvrsdasm nqsldykskd
      241 tntdlrhevl ntfrsnllkk ferlyegtat qrnptllnei ytelyitese sgeisnehev
      301 rqietqsrra tiedtaikcs diftplpgqd kairtvltkg vagigktvsv qkfildwaeg
      361 kenqdvqlif plpfreinlm kdktlslsdl lhvffpetke meissdeykv lfifdgldec
      421 rlsldfkskv klcnisesas vdellmnliv gnllpsaliw itsrpaaadl vpsecvhrvt
      481 evrgfnepqk eeyfrkrisd qsladriish lkssrslyim chipvfcwis savlekmlsr
      541 aesgeipktl tqmythflil qtnikhgkdy ekkvtdedmi lklgkvafqq lvkgnlifye
      601 edlrecgidv teasvysglc tqifreelgl yqgkvfcfvh lsiqehlaal yvhlswtnhn
      661 rnvfdqftkl slrskvkkqf klsssehvsl selhqravkd alqsknghld lflrfllgls
      721 veshqillqq imklkrnssd snektvelik kkirtiespe ksinlfhcln elgdrslvke
      781 iqqyltsgnl sganlsssqw savvfvllts eeelnefrld kfvegkdkae nmkvlqkllp
      841 vikesrsvql sycgvtdegc saltsalrsn pshlreldls vnkirdsgvk clcagledph
      901 ckleklw
//
LOCUS       XP_026128575             904 aa            linear   VRT 18-JUN-2025
DEFINITION  protein NLRC3-like isoform X3 [Carassius auratus].
ACCESSION   XP_026128575
VERSION     XP_026128575.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272790.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..904
                     /product="protein NLRC3-like isoform X3"
                     /calculated_mol_wt=102924
     Region          253..324
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          339..506
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          588..648
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          650..779
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          <813..>900
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     CDS             1..904
                     /gene="LOC113109173"
                     /coded_by="XM_026272790.1:395..3109"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lssvhqkrse aesscvsvrs dasmdrpihf ksgdtntdlr icsqrssspd
      181 hscvslksdg smgrppalsd eavtsdpsra dgersisggv ssvfclnnts vtaslnkhdq
      241 avndelqrvk eqhktsmknk yerlceglkl qenesllnsi ytqlyiiege regvneehev
      301 lqmektartq hsqdapiycn difkasaeag seekeqiktv ltkgiagigk tvsvqkfild
      361 waegkanqdv dfmfvlpfre lnlirdhqys lhtllldfhp elqdldsqiy eeckvvfifd
      421 gldesritlm fsdaqkvcdv tetssvavlm sklmkgellp saliwitsrp aaanqipsey
      481 ihrlteiqgf tepqkeeyfr krisdehqas riishirrar slhimchipv fcwisstvlq
      541 klleedlrae ipqtltemyi hflliqinmr kqkyeerdpe kllpsdrevi vklaevafkq
      601 lmegnvmfye edliesgvdv tdasvysgic teifkqesvi hqrkvysfih lsvqeflaaf
      661 ylfycyltkn kktlrefrly rsvkvslydl ltsavdkale skngrldlfl rfllgvsles
      721 nqrllqdllt htenssetis rttryikdki kssdhlsadq sinlflclle vkdqtlfrei
      781 qefvksdkhs ekklspahcs tisymiqmse epldeldpkk yntsaegrrr lipavnncrk
      841 avlrycdvtd egcsalasal rsnpshlrel dlswntirdl gvkhlcavle dprckleklw
      901 tlsi
//
LOCUS       XP_026128576             879 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X4
            [Carassius auratus].
ACCESSION   XP_026128576
VERSION     XP_026128576.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272791.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..879
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..879
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X4"
                     /calculated_mol_wt=99897
     Region          291..362
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          377..544
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          630..686
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          688..817
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..879
                     /gene="LOC113109173"
                     /coded_by="XM_026272791.1:390..3029"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lssvhqkrse aesscvsvrs dasmdrpihf ksgdtntdlr icsqrssspd
      181 hscvslksdg smgrppalsd eavtsdpric sqrssspdhs cvslksdesm ldppklsdea
      241 vtsdpsradg ersisggfss vfclnntsvt aslnkhdqav ndelqrvkeq hktsmknkye
      301 rlceglklqe nesllnsiyt qlyiiegere gvneehevlq mektartqps qdtpiycndi
      361 fkasaeagse ekeqiktvlt kgiagigktv svqkfildwa egkanqdvdf mfvlpfreln
      421 lirdhqyslh rllldfhpel rdldsqiyee ckvvfifdgl desritlmfs daqkvcdvte
      481 tssvavlmsk lmkgellpsa liwitsrpaa anqipseyih rlteiqgfte pqkeeyfrkr
      541 isdehqasri ishirrarsl himchipvfc wisstvlqkl leedlraeip qtltemyihf
      601 lliqinmrkq kyeerdpekl lpsdrevmvk laevafkqlm kgnvmfyeed liesgidvtd
      661 asvfsgicte ifkqesvihq rkvysfihls vqeflaafyl fyccltknkk tlhefrlnrs
      721 ykvslydllt savdkalese nghldlflrf llgvslesnq rllqdlltht enssktisrt
      781 tqdikhkiks shhlsadqsi nlflcllevk dqtlfreiqe fvksdkhsek lspahcstis
      841 ymiqmseepl delnpmkynt saegrrrlip avincrkav
//
LOCUS       XP_026128577             879 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X5
            [Carassius auratus].
ACCESSION   XP_026128577
VERSION     XP_026128577.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272792.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..879
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..879
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X5"
                     /calculated_mol_wt=100044
     Region          291..362
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          377..544
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          630..686
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          688..817
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..879
                     /gene="LOC113109173"
                     /coded_by="XM_026272792.1:390..3029"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lssvhqkrse aesscvsvrs dasmdrpihf ksgdtntdls svdqkrseae
      181 sscvsvrsda smdppmkfks gdtktdlric sqrssspdhs cvslksdesm ldppklsdea
      241 vtsdpsradg ersisggfss vfclnntsvt aslnkhdqav ndelqrvkeq hktsmknkye
      301 rlceglklqe nesllnsiyt qlyiiegere gvneehevlq mektartqps qdtpiycndi
      361 fkasaeagse ekeqiktvlt kgiagigktv svqkfildwa egkanqdvdf mfvlpfreln
      421 lirdhqyslh rllldfhpel rdldsqiyee ckvvfifdgl desritlmfs daqkvcdvte
      481 tssvavlmsk lmkgellpsa liwitsrpaa anqipseyih rlteiqgfte pqkeeyfrkr
      541 isdehqasri ishirrarsl himchipvfc wisstvlqkl leedlraeip qtltemyihf
      601 lliqinmrkq kyeerdpekl lpsdrevmvk laevafkqlm kgnvmfyeed liesgidvtd
      661 asvfsgicte ifkqesvihq rkvysfihls vqeflaafyl fyccltknkk tlhefrlnrs
      721 ykvslydllt savdkalese nghldlflrf llgvslesnq rllqdlltht enssktisrt
      781 tqdikhkiks shhlsadqsi nlflcllevk dqtlfreiqe fvksdkhsek lspahcstis
      841 ymiqmseepl delnpmkynt saegrrrlip avincrkav
//
LOCUS       XP_026128578             878 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X6
            [Carassius auratus].
ACCESSION   XP_026128578
VERSION     XP_026128578.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272793.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..878
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..878
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X6"
                     /calculated_mol_wt=99810
     Region          290..361
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          376..543
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          629..685
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          687..816
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..878
                     /gene="LOC113109173"
                     /coded_by="XM_026272793.1:390..3026"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lssvhqkrse aesscvsvrs dasmdrpihf ksgdtntdlr icsqrssspd
      181 hscvslksdg smgrppalsd eavtsdpric sqrssspdhs cvslksdesm ldppklsdea
      241 vtsdpradge rsisggfssv fclnntsvta slnkhdqavn delqrvkeqh ktsmknkyer
      301 lceglklqen esllnsiytq lyiiegereg vneehevlqm ektartqpsq dtpiycndif
      361 kasaeagsee keqiktvltk giagigktvs vqkfildwae gkanqdvdfm fvlpfrelnl
      421 irdhqyslhr llldfhpelr dldsqiyeec kvvfifdgld esritlmfsd aqkvcdvtet
      481 ssvavlmskl mkgellpsal iwitsrpaaa nqipseyihr lteiqgftep qkeeyfrkri
      541 sdehqasrii shirrarslh imchipvfcw isstvlqkll eedlraeipq tltemyihfl
      601 liqinmrkqk yeerdpekll psdrevmvkl aevafkqlmk gnvmfyeedl iesgidvtda
      661 svfsgictei fkqesvihqr kvysfihlsv qeflaafylf yccltknkkt lhefrlnrsy
      721 kvslydllts avdkalesen ghldlflrfl lgvslesnqr llqdllthte nssktisrtt
      781 qdikhkikss hhlsadqsin lflcllevkd qtlfreiqef vksdkhsekl spahcstisy
      841 miqmseepld elnpmkynts aegrrrlipa vincrkav
//
LOCUS       XP_026128579             878 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X7
            [Carassius auratus].
ACCESSION   XP_026128579
VERSION     XP_026128579.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272794.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..878
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..878
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X7"
                     /calculated_mol_wt=99957
     Region          290..361
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          376..543
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          629..685
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          687..816
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..878
                     /gene="LOC113109173"
                     /coded_by="XM_026272794.1:390..3026"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lssvhqkrse aesscvsvrs dasmdrpihf ksgdtntdls svdqkrseae
      181 sscvsvrsda smdppmkfks gdtktdlric sqrssspdhs cvslksdesm ldppklsdea
      241 vtsdpradge rsisggfssv fclnntsvta slnkhdqavn delqrvkeqh ktsmknkyer
      301 lceglklqen esllnsiytq lyiiegereg vneehevlqm ektartqpsq dtpiycndif
      361 kasaeagsee keqiktvltk giagigktvs vqkfildwae gkanqdvdfm fvlpfrelnl
      421 irdhqyslhr llldfhpelr dldsqiyeec kvvfifdgld esritlmfsd aqkvcdvtet
      481 ssvavlmskl mkgellpsal iwitsrpaaa nqipseyihr lteiqgftep qkeeyfrkri
      541 sdehqasrii shirrarslh imchipvfcw isstvlqkll eedlraeipq tltemyihfl
      601 liqinmrkqk yeerdpekll psdrevmvkl aevafkqlmk gnvmfyeedl iesgidvtda
      661 svfsgictei fkqesvihqr kvysfihlsv qeflaafylf yccltknkkt lhefrlnrsy
      721 kvslydllts avdkalesen ghldlflrfl lgvslesnqr llqdllthte nssktisrtt
      781 qdikhkikss hhlsadqsin lflcllevkd qtlfreiqef vksdkhsekl spahcstisy
      841 miqmseepld elnpmkynts aegrrrlipa vincrkav
//
LOCUS       XP_026128580             869 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X8
            [Carassius auratus].
ACCESSION   XP_026128580
VERSION     XP_026128580.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272795.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..869
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X8"
                     /calculated_mol_wt=98606
     Region          215..285
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          296..463
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          540..600
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          602..742
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          651..>869
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     CDS             1..869
                     /gene="LOC113109173"
                     /coded_by="XM_026272795.1:395..3004"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lrlfhqkrse aesscvsvrs dwsmdppvhf ksgdtktdls svdqkrseae
      181 sscvsvrsda smnqsldyks kdtntdlrhe vlntfrsnll kkferlyegt atqrnptlln
      241 eiytelyite sesgeisneh evrqietqsr ratiedtaik csdiftplpg qdkairtvlt
      301 kgvagigktv svqkfildwa egkenqdvql ifplpfrein lmkdktlsls dllhvffpet
      361 kemeissdey kvlfifdgld ecrlsldfks kvklcnises asvdellmnl ivgnllpsal
      421 iwitsrpaaa dlvpsecvhr vtevrgfnep qkeeyfrkri sdqsladrii shlkssrsly
      481 imchipvfcw issavlekml sraesgeipk tltqmythfl ilqtnikhgk dyekkvtded
      541 milklgkvaf qqlvkgnlif yeedlrecgi dvteasvysg lctqifreel glyqgkvfcf
      601 vhlsiqehla alyvhlswtn hnrnvfdqft klslrskvkk qfklsssehv slselhqrav
      661 kdalqskngh ldlflrfllg lsveshqill qqimklkrns sdsnektvel ikkkirties
      721 peksinlfhc lnelgdrslv keiqqyltsg nlsganlsss qwsavvfvll tseeelnefr
      781 ldkfvegkdk aenmkvlqkl lpvikesrsv qlsycgvtde gcsaltsalr snpshlreld
      841 lsvnkirdsg vkclcagled phckleklw
//
LOCUS       XP_026128581             842 aa            linear   VRT 18-JUN-2025
DEFINITION  protein NLRC3-like isoform X9 [Carassius auratus].
ACCESSION   XP_026128581
VERSION     XP_026128581.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272796.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..842
                     /product="protein NLRC3-like isoform X9"
                     /calculated_mol_wt=95916
     Region          253..324
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          339..506
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          588..648
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          650..779
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..842
                     /gene="LOC113109173"
                     /coded_by="XM_026272796.1:395..2923"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lssvhqkrse aesscvsvrs dasmdrpihf ksgdtntdlr icsqrssspd
      181 hscvslksdg smgrppalsd eavtsdpsra dgersisggv ssvfclnnts vtaslnkhdq
      241 avndelqrvk eqhktsmknk yerlceglkl qenesllnsi ytqlyiiege regvneehev
      301 lqmektartq hsqdapiycn difkasaeag seekeqiktv ltkgiagigk tvsvqkfild
      361 waegkanqdv dfmfvlpfre lnlirdhqys lhtllldfhp elqdldsqiy eeckvvfifd
      421 gldesritlm fsdaqkvcdv tetssvavlm sklmkgellp saliwitsrp aaanqipsey
      481 ihrlteiqgf tepqkeeyfr krisdehqas riishirrar slhimchipv fcwisstvlq
      541 klleedlrae ipqtltemyi hflliqinmr kqkyeerdpe kllpsdrevi vklaevafkq
      601 lmegnvmfye edliesgvdv tdasvysgic teifkqesvi hqrkvysfih lsvqeflaaf
      661 ylfycyltkn kktlrefrly rsvkvslydl ltsavdkale skngrldlfl rfllgvsles
      721 nqrllqdllt htenssetis rttryikdki kssdhlsadq sinlflclle vkdqtlfrei
      781 qefvksdkhs ekklspahcs tisymiqmse epldeldpkk yntsaegrrr lipavnncrk
      841 av
//
LOCUS       XP_026128582             841 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X10
            [Carassius auratus].
ACCESSION   XP_026128582
VERSION     XP_026128582.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272797.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..841
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..841
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X10"
                     /calculated_mol_wt=95956
     Region          253..324
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          339..506
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          592..648
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          650..779
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..841
                     /gene="LOC113109173"
                     /coded_by="XM_026272797.1:390..2915"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlrlfhqkrs laesscvsvr rdasmdppvk
      121 kfksedtktd lssvhqkrse aesscvsvrs dasmdrpihf ksgdtntdls svdqkrseae
      181 sscvsvrsda smdppmkfks gdtktdlsra dgersisggf ssvfclnnts vtaslnkhdq
      241 avndelqrvk eqhktsmknk yerlceglkl qenesllnsi ytqlyiiege regvneehev
      301 lqmektartq psqdtpiycn difkasaeag seekeqiktv ltkgiagigk tvsvqkfild
      361 waegkanqdv dfmfvlpfre lnlirdhqys lhrllldfhp elrdldsqiy eeckvvfifd
      421 gldesritlm fsdaqkvcdv tetssvavlm sklmkgellp saliwitsrp aaanqipsey
      481 ihrlteiqgf tepqkeeyfr krisdehqas riishirrar slhimchipv fcwisstvlq
      541 klleedlrae ipqtltemyi hflliqinmr kqkyeerdpe kllpsdrevm vklaevafkq
      601 lmkgnvmfye edliesgidv tdasvfsgic teifkqesvi hqrkvysfih lsvqeflaaf
      661 ylfyccltkn kktlhefrln rsykvslydl ltsavdkale senghldlfl rfllgvsles
      721 nqrllqdllt htenssktis rttqdikhki ksshhlsadq sinlflclle vkdqtlfrei
      781 qefvksdkhs eklspahcst isymiqmsee pldelnpmky ntsaegrrrl ipavincrka
      841 v
//
LOCUS       XP_026128583             727 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X11
            [Carassius auratus].
ACCESSION   XP_026128583
VERSION     XP_026128583.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272798.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..727
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..727
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X11"
                     /calculated_mol_wt=83221
     Region          139..210
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          225..392
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          478..534
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          536..665
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..727
                     /gene="LOC113109173"
                     /coded_by="XM_026272798.1:227..2410"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcrlfh hkrslaessc vsvrsdasmd ppvkkfkcgd tktdlricsq
       61 rssspdhscv slksdesmld ppklsdeavt sdpsradger sisggfssvf clnntsvtas
      121 lnkhdqavnd elqrvkeqhk tsmknkyerl ceglklqene sllnsiytql yiiegeregv
      181 neehevlqme ktartqpsqd tpiycndifk asaeagseek eqiktvltkg iagigktvsv
      241 qkfildwaeg kanqdvdfmf vlpfrelnli rdhqyslhrl lldfhpelrd ldsqiyeeck
      301 vvfifdglde sritlmfsda qkvcdvtets svavlmsklm kgellpsali witsrpaaan
      361 qipseyihrl teiqgftepq keeyfrkris dehqasriis hirrarslhi mchipvfcwi
      421 sstvlqklle edlraeipqt ltemyihfll iqinmrkqky eerdpekllp sdrevmvkla
      481 evafkqlmkg nvmfyeedli esgidvtdas vfsgicteif kqesvihqrk vysfihlsvq
      541 eflaafylfy ccltknkktl hefrlnrsyk vslydlltsa vdkaleseng hldlflrfll
      601 gvslesnqrl lqdllthten ssktisrttq dikhkikssh hlsadqsinl flcllevkdq
      661 tlfreiqefv ksdkhsekls pahcstisym iqmseeplde lnpmkyntsa egrrrlipav
      721 incrkav
//
LOCUS       XP_026128584             688 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X12
            [Carassius auratus].
ACCESSION   XP_026128584
VERSION     XP_026128584.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272799.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..688
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X12"
                     /calculated_mol_wt=78863
     Region          100..171
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          186..353
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          439..495
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          497..626
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..688
                     /gene="LOC113109173"
                     /coded_by="XM_026272799.1:227..2293"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvd qkrseaessc vsvrsdasmd ppmkfksgdt ktdlsradge
       61 rsisggfssv fclnntsvta slnkhdqavn delqrvkeqh ktsmknkyer lceglklqen
      121 esllnsiytq lyiiegereg vneehevlqm ektartqpsq dtpiycndif kasaeagsee
      181 keqiktvltk giagigktvs vqkfildwae gkanqdvdfm fvlpfrelnl irdhqyslhr
      241 llldfhpelr dldsqiyeec kvvfifdgld esritlmfsd aqkvcdvtet ssvavlmskl
      301 mkgellpsal iwitsrpaaa nqipseyihr lteiqgftep qkeeyfrkri sdehqasrii
      361 shirrarslh imchipvfcw isstvlqkll eedlraeipq tltemyihfl liqinmrkqk
      421 yeerdpekll psdrevmvkl aevafkqlmk gnvmfyeedl iesgidvtda svfsgictei
      481 fkqesvihqr kvysfihlsv qeflaafylf yccltknkkt lhefrlnrsy kvslydllts
      541 avdkalesen ghldlflrfl lgvslesnqr llqdllthte nssktisrtt qdikhkikss
      601 hhlsadqsin lflcllevkd qtlfreiqef vksdkhsekl spahcstisy miqmseepld
      661 elnpmkynts aegrrrlipa vincrkav
//
LOCUS       XP_026128585             688 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X13
            [Carassius auratus].
ACCESSION   XP_026128585
VERSION     XP_026128585.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272800.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..688
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X13"
                     /calculated_mol_wt=78922
     Region          100..171
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          186..353
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          439..495
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          497..626
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..688
                     /gene="LOC113109173"
                     /coded_by="XM_026272800.1:52..2118"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 mdppvkkfkc gdtktdlric sqrssspdhs cvslksdesm ldppklsdea vtsdpradge
       61 rsisggfssv fclnntsvta slnkhdqavn delqrvkeqh ktsmknkyer lceglklqen
      121 esllnsiytq lyiiegereg vneehevlqm ektartqpsq dtpiycndif kasaeagsee
      181 keqiktvltk giagigktvs vqkfildwae gkanqdvdfm fvlpfrelnl irdhqyslhr
      241 llldfhpelr dldsqiyeec kvvfifdgld esritlmfsd aqkvcdvtet ssvavlmskl
      301 mkgellpsal iwitsrpaaa nqipseyihr lteiqgftep qkeeyfrkri sdehqasrii
      361 shirrarslh imchipvfcw isstvlqkll eedlraeipq tltemyihfl liqinmrkqk
      421 yeerdpekll psdrevmvkl aevafkqlmk gnvmfyeedl iesgidvtda svfsgictei
      481 fkqesvihqr kvysfihlsv qeflaafylf yccltknkkt lhefrlnrsy kvslydllts
      541 avdkalesen ghldlflrfl lgvslesnqr llqdllthte nssktisrtt qdikhkikss
      601 hhlsadqsin lflcllevkd qtlfreiqef vksdkhsekl spahcstisy miqmseepld
      661 elnpmkynts aegrrrlipa vincrkav
//
LOCUS       XP_026128586             803 aa            linear   VRT 18-JUN-2025
DEFINITION  protein NLRC3-like isoform X14 [Carassius auratus].
ACCESSION   XP_026128586
VERSION     XP_026128586.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272801.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..803
                     /product="protein NLRC3-like isoform X14"
                     /calculated_mol_wt=91440
     Region          214..285
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          300..467
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          549..609
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          611..740
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..803
                     /gene="LOC113109173"
                     /coded_by="XM_026272801.1:395..2806"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcssvh qkrseaessc vsvrsdwsmd hpenfksgdt ktvlssvhqk
       61 rseaesscvs vrsdwsmdhp enfksgdtkt vlssvhqkrs eaesscvsvr sdasmdrpih
      121 fksgdtntdl ricsqrsssp dhscvslksd gsmgrppals deavtsdpsr adgersisgg
      181 vssvfclnnt svtaslnkhd qavndelqrv keqhktsmkn kyerlceglk lqenesllns
      241 iytqlyiieg eregvneehe vlqmektart qhsqdapiyc ndifkasaea gseekeqikt
      301 vltkgiagig ktvsvqkfil dwaegkanqd vdfmfvlpfr elnlirdhqy slhtllldfh
      361 pelqdldsqi yeeckvvfif dgldesritl mfsdaqkvcd vtetssvavl msklmkgell
      421 psaliwitsr paaanqipse yihrlteiqg ftepqkeeyf rkrisdehqa sriishirra
      481 rslhimchip vfcwisstvl qklleedlra eipqtltemy ihflliqinm rkqkyeerdp
      541 ekllpsdrev ivklaevafk qlmegnvmfy eedliesgvd vtdasvysgi cteifkqesv
      601 ihqrkvysfi hlsvqeflaa fylfycyltk nkktlrefrl yrsvkvslyd lltsavdkal
      661 eskngrldlf lrfllgvsle snqrllqdll thtensseti srttryikdk ikssdhlsad
      721 qsinlflcll evkdqtlfre iqefvksdkh sekklspahc stisymiqms eepldeldpk
      781 kyntsaegrr rlipavnncr kav
//
LOCUS       XP_026128587             765 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X15
            [Carassius auratus].
ACCESSION   XP_026128587
VERSION     XP_026128587.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272802.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..765
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X15"
                     /calculated_mol_wt=87311
     Region          177..248
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          263..430
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          516..572
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          574..703
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..765
                     /gene="LOC113109173"
                     /coded_by="XM_026272802.1:227..2524"
                     /db_xref="GeneID:113109173"
ORIGIN      
        1 medtqtstdq efspgcrlfh hkrslaessc vsvrsdasmd ppvkkfkcgd tktdlssvdq
       61 krseaesscv svrsdasmdp pmkfksgdtk tdlricsqrs sspdhscvsl ksdesmldpp
      121 klsdeavtsd psradgersi sggfssvfcl nntsvtasln khdqavndel qrvkeqhkts
      181 mknkyerlce glklqenesl lnsiytqlyi iegeregvne ehevlqmekt artqpsqdtp
      241 iycndifkas aeagseekeq iktvltkgia gigktvsvqk fildwaegka nqdvdfmfvl
      301 pfrelnlird hqyslhrlll dfhpelrdld sqiyeeckvv fifdgldesr itlmfsdaqk
      361 vcdvtetssv avlmsklmkg ellpsaliwi tsrpaaanqi pseyihrlte iqgftepqke
      421 eyfrkrisde hqasriishi rrarslhimc hipvfcwiss tvlqklleed lraeipqtlt
      481 emyihflliq inmrkqkyee rdpekllpsd revmvklaev afkqlmkgnv mfyeedlies
      541 gidvtdasvf sgicteifkq esvihqrkvy sfihlsvqef laafylfycc ltknkktlhe
      601 frlnrsykvs lydlltsavd kalesenghl dlflrfllgv slesnqrllq dllthtenss
      661 ktisrttqdi khkiksshhl sadqsinlfl cllevkdqtl freiqefvks dkhseklspa
      721 hcstisymiq mseepldeln pmkyntsaeg rrrlipavin crkav
//
LOCUS       XP_026128588            1045 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 12-like [Carassius
            auratus].
ACCESSION   XP_026128588
VERSION     XP_026128588.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272803.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1045
                     /product="NACHT, LRR and PYD domains-containing protein
                     12-like"
                     /calculated_mol_wt=118564
     Region          221..292
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          307..474
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          556..616
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          618..750
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          794..1030
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          837..865
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          866..894
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          895..923
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          924..952
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          953..981
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          982..1006
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..1045
                     /gene="LOC113109176"
                     /coded_by="XM_026272803.1:10..3147"
                     /db_xref="GeneID:113109176"
ORIGIN      
        1 mggvcmlltp evscacavci trthlcveie sklsiltecn ftfrrlknwh knlitascqs
       61 vimeirerss spdhtreslk shrsmnppes sddpvtsdlr icsqrssspd hscvslksde
      121 smgrppnlsd eavtsdpric sqrssspdhs yvslksdgsm ayppklsdea vtsdpsradg
      181 ersisggvss vfclnntsvt aslnkhdqav ndelqrvkeq hktsmknkye rlceglklqe
      241 nesllnsiyt qlyiiegere gvneehevlq mektartqps qdapiycndi fkasaeagse
      301 ekeqiktvlt kgiagigktv svqkfildwa egkanqdvdf mfvlpfreln lirdhqyslh
      361 rllldfhpel qdldsqiyee ckvvfifdgl desritlmfs daqkvcdvte tssvavlmsk
      421 lmkgellpsa liwitsrpaa anqipskyih rlteiqgfte pqkeeyfrkr isdehqasri
      481 ishirrarsl himchipvfc wisstvlqkl leedlraeip qtltemyihf lliqinmrkq
      541 kyeerdpekl lpsnrevivk laevafkqlm kgnvmfyeed liesgidvtd asvysgicte
      601 ifkqesvihq revysfihls vqeflaafyl fycyltknkk tlhefrlyry devslydllt
      661 savdkalesk ngcldlflrf llgvslesnq rllqdlltht enssetirdt tryikhkiky
      721 dpehhplsad qsinlflcll evkdqtlfre iqefvksdkh seklsaahcs tisymiqmse
      781 epldeldpmk yntsdegrrr lipavincrk avlrgcgvtd egcsalssal rsnpshlrel
      841 dlsgnkirds gvkclcavle dtrckletlw lidcgvtdeg csalasalrs npshlreldl
      901 senkirdsgv kclcagledp rckleklrls ycdvtdegcs vltsalrsnp shlrqlslsv
      961 nkirdlgvkc lcagledpry kleklrlrdc dvtdegcsal tsalrsnpsh lrelnlilnn
     1021 lrqsgvklls dlkhdqrykl erldy
//
LOCUS       XP_026128589            1031 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X1
            [Carassius auratus].
ACCESSION   XP_026128589
VERSION     XP_026128589.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272804.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1031
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1031
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X1"
                     /calculated_mol_wt=116311
     Region          176..247
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          262..429
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          511..571
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          573..702
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          737..>986
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Region          790..818
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          819..847
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          848..868
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          877..905
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          906..934
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          935..959
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..1031
                     /gene="LOC113109177"
                     /coded_by="XM_026272804.1:45..3140"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 mghpvqfksg dtntdlssvq qerseaessc vsvrsdasmg hpvqfksgdt ntdlssvqqe
       61 rseaesscvs vrsnasmghp vqfksgdtnt dlricsqrss spdhscvslk sdrsmgnrpk
      121 lsdeavtsdp sradgersis ggvssvfcln ntsvtaslnk hdqavndelq rvkeqhktsm
      181 knkyerlceg lklqenesll nsiytqlyii egeregvnee hevlqmekta rtqpsqdapi
      241 ycndifkasa eagseekeqi ktvltkgiag igktvsvqkf ildwaegkan qdvdfmfvlp
      301 frelnlirdh qyslhrllld fhpelqdlds qiyeeckvvf ifdgldesri tlmfsdarkv
      361 cdvtetssva vlmsklmkge llpsaliwit srpaaanqip seyihrltei qgftepqkee
      421 yfrkrisdeh qasriishir rarslhimch ipvfcwisst vlqklleedl raeipqtlte
      481 myihflliqi nmrkqkyeer dpekllpsnr evivklaeva fkqlmegnvm fyeedliesg
      541 idvtdasvys gicteifkqe svihqrkvys fihlsvqefl aafylfycyl tenkktlhel
      601 ssytcdkvsl ydlltsavdk alksengrld lflrfllgvs lesnqrllqd llthtensse
      661 tisrttqdik erikssdhls adqsinlflc llevkdqtlf reiekflksd khtekklspa
      721 hcstisytiq mseepldeln lqkyntsaeg rrrlipaain crkavlwkcd gtdegcsalt
      781 salrsnpshl reldlsenki rdlgvkrlca gledprckle ilwlsdcdvt degcsalasa
      841 lisnpshlte lilsrnklgd sgvkhlsavl edphcklknl wlsycgitde gcsalasalr
      901 snpshlreld laenkirdlg vkhlcagled prckleklwl rdccvtdegc salasalrsn
      961 sshlrelnls rnnlgpsecr tlsiqlmvnk ihyretsqsq nqqrlktqrh tasqrvktqg
     1021 hghighlgrt k
//
LOCUS       XP_026128590             999 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X2
            [Carassius auratus].
ACCESSION   XP_026128590
VERSION     XP_026128590.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272805.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..999
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X2"
                     /calculated_mol_wt=112741
     Region          176..247
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          262..429
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          511..571
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          573..702
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          737..>975
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Region          790..818
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          819..847
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          848..868
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          877..905
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          906..934
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          935..959
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..999
                     /gene="LOC113109177"
                     /coded_by="XM_026272805.1:44..3043"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 mghpvqfksg dtntdlssvq qerseaessc vsvrsdasmg hpvqfksgdt ntdlssvqqe
       61 rseaesscvs vrsnasmghp vqfksgdtnt dlricsqrss spdhscvslk sdrsmgnrpk
      121 lsdeavtsdp sradgersis ggvssvfcln ntsvtaslnk hdqavndelq rvkeqhktsm
      181 knkyerlceg lklqenesll nsiytqlyii egeregvnee hevlqmekta rtqpsqdapi
      241 ycndifkasa eagseekeqi ktvltkgiag igktvsvqkf ildwaegkan qdvdfmfvlp
      301 frelnlirdh qyslhrllld fhpelqdlds qiyeeckvvf ifdgldesri tlmfsdarkv
      361 cdvtetssva vlmsklmkge llpsaliwit srpaaanqip seyihrltei qgftepqkee
      421 yfrkrisdeh qasriishir rarslhimch ipvfcwisst vlqklleedl raeipqtlte
      481 myihflliqi nmrkqkyeer dpekllpsnr evivklaeva fkqlmegnvm fyeedliesg
      541 idvtdasvys gicteifkqe svihqrkvys fihlsvqefl aafylfycyl tenkktlhel
      601 ssytcdkvsl ydlltsavdk alksengrld lflrfllgvs lesnqrllqd llthtensse
      661 tisrttqdik erikssdhls adqsinlflc llevkdqtlf reiekflksd khtekklspa
      721 hcstisytiq mseepldeln lqkyntsaeg rrrlipaain crkavlwkcd gtdegcsalt
      781 salrsnpshl reldlsenki rdlgvkrlca gledprckle ilwlsdcdvt degcsalasa
      841 lisnpshlte lilsrnklgd sgvkhlsavl edphcklknl wlsycgitde gcsalasalr
      901 snpshlreld laenkirdlg vkhlcagled prckleklwl rdccvtdegc salasalrsn
      961 sshlrelnls rnnlgpsevk llsdleydsr yklqtlfyl
//
LOCUS       XP_026128591             994 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X3
            [Carassius auratus].
ACCESSION   XP_026128591
VERSION     XP_026128591.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272806.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..994
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X3"
                     /calculated_mol_wt=112799
     Region          139..210
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          225..392
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          474..534
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          536..665
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          700..>949
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Region          753..781
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          782..810
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          811..831
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          840..868
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          869..897
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          898..922
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..994
                     /gene="LOC113109177"
                     /coded_by="XM_026272806.1:78..3062"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 mrrrheislf tascqsvime irerssspdh treslkshrs mnppessddp vtsdpricsq
       61 rssspdhscv slksdrsmgn rpklsdeavt sdpsradger sisggvssvf clnntsvtas
      121 lnkhdqavnd elqrvkeqhk tsmknkyerl ceglklqene sllnsiytql yiiegeregv
      181 neehevlqme ktartqpsqd apiycndifk asaeagseek eqiktvltkg iagigktvsv
      241 qkfildwaeg kanqdvdfmf vlpfrelnli rdhqyslhrl lldfhpelqd ldsqiyeeck
      301 vvfifdglde sritlmfsda rkvcdvtets svavlmsklm kgellpsali witsrpaaan
      361 qipseyihrl teiqgftepq keeyfrkris dehqasriis hirrarslhi mchipvfcwi
      421 sstvlqklle edlraeipqt ltemyihfll iqinmrkqky eerdpekllp snrevivkla
      481 evafkqlmeg nvmfyeedli esgidvtdas vysgicteif kqesvihqrk vysfihlsvq
      541 eflaafylfy cyltenkktl helssytcdk vslydlltsa vdkalkseng rldlflrfll
      601 gvslesnqrl lqdllthten ssetisrttq dikerikssd hlsadqsinl flcllevkdq
      661 tlfreiekfl ksdkhtekkl spahcstisy tiqmseepld elnlqkynts aegrrrlipa
      721 aincrkavlw kcdgtdegcs altsalrsnp shlreldlse nkirdlgvkr lcagledprc
      781 kleilwlsdc dvtdegcsal asalisnpsh ltelilsrnk lgdsgvkhls avledphckl
      841 knlwlsycgi tdegcsalas alrsnpshlr eldlaenkir dlgvkhlcag ledprcklek
      901 lwlrdccvtd egcsalasal rsnsshlrel nlsrnnlgps ecrtlsiqlm vnkihyrets
      961 qsqnqqrlkt qrhtasqrvk tqghghighl grtk
//
LOCUS       XP_026128592             987 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X4
            [Carassius auratus].
ACCESSION   XP_026128592
VERSION     XP_026128592.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272807.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..987
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..987
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X4"
                     /calculated_mol_wt=111104
     Region          176..247
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          262..429
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          511..571
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          573..702
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          737..>975
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Region          790..818
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          819..847
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          848..868
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          877..905
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          906..934
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          935..959
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..987
                     /gene="LOC113109177"
                     /coded_by="XM_026272807.1:44..3007"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 mghpvqfksg dtntdlssvq qerseaessc vsvrsdasmg hpvqfksgdt ntdlssvqqe
       61 rseaesscvs vrsnasmghp vqfksgdtnt dlricsqrss spdhscvslk sdrsmgnrpk
      121 lsdeavtsdp sradgersis ggvssvfcln ntsvtaslnk hdqavndelq rvkeqhktsm
      181 knkyerlceg lklqenesll nsiytqlyii egeregvnee hevlqmekta rtqpsqdapi
      241 ycndifkasa eagseekeqi ktvltkgiag igktvsvqkf ildwaegkan qdvdfmfvlp
      301 frelnlirdh qyslhrllld fhpelqdlds qiyeeckvvf ifdgldesri tlmfsdarkv
      361 cdvtetssva vlmsklmkge llpsaliwit srpaaanqip seyihrltei qgftepqkee
      421 yfrkrisdeh qasriishir rarslhimch ipvfcwisst vlqklleedl raeipqtlte
      481 myihflliqi nmrkqkyeer dpekllpsnr evivklaeva fkqlmegnvm fyeedliesg
      541 idvtdasvys gicteifkqe svihqrkvys fihlsvqefl aafylfycyl tenkktlhel
      601 ssytcdkvsl ydlltsavdk alksengrld lflrfllgvs lesnqrllqd llthtensse
      661 tisrttqdik erikssdhls adqsinlflc llevkdqtlf reiekflksd khtekklspa
      721 hcstisytiq mseepldeln lqkyntsaeg rrrlipaain crkavlwkcd gtdegcsalt
      781 salrsnpshl reldlsenki rdlgvkrlca gledprckle ilwlsdcdvt degcsalasa
      841 lisnpshlte lilsrnklgd sgvkhlsavl edphcklknl wlsycgitde gcsalasalr
      901 snpshlreld laenkirdlg vkhlcagled prckleklwl rdccvtdegc salasalrsn
      961 sshlrelnls rnnlgpseds qysadge
//
LOCUS       XP_026128593             976 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X5
            [Carassius auratus].
ACCESSION   XP_026128593
VERSION     XP_026128593.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272808.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..976
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..976
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X5"
                     /calculated_mol_wt=110682
     Region          121..192
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          207..374
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          456..516
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          518..647
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          682..>931
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Region          735..763
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          764..792
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          793..813
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          822..850
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          851..879
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          880..904
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..976
                     /gene="LOC113109177"
                     /coded_by="XM_026272808.1:481..3411"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 meirersssp dhtreslksh rsmnppessd dpvtsdpric sqrssspdhs cvslksdrsm
       61 gnrpklsdea vtsdpsradg ersisggvss vfclnntsvt aslnkhdqav ndelqrvkeq
      121 hktsmknkye rlceglklqe nesllnsiyt qlyiiegere gvneehevlq mektartqps
      181 qdapiycndi fkasaeagse ekeqiktvlt kgiagigktv svqkfildwa egkanqdvdf
      241 mfvlpfreln lirdhqyslh rllldfhpel qdldsqiyee ckvvfifdgl desritlmfs
      301 darkvcdvte tssvavlmsk lmkgellpsa liwitsrpaa anqipseyih rlteiqgfte
      361 pqkeeyfrkr isdehqasri ishirrarsl himchipvfc wisstvlqkl leedlraeip
      421 qtltemyihf lliqinmrkq kyeerdpekl lpsnrevivk laevafkqlm egnvmfyeed
      481 liesgidvtd asvysgicte ifkqesvihq rkvysfihls vqeflaafyl fycyltenkk
      541 tlhelssytc dkvslydllt savdkalkse ngrldlflrf llgvslesnq rllqdlltht
      601 enssetisrt tqdikeriks sdhlsadqsi nlflcllevk dqtlfreiek flksdkhtek
      661 klspahcsti sytiqmseep ldelnlqkyn tsaegrrrli paaincrkav lwkcdgtdeg
      721 csaltsalrs npshlreldl senkirdlgv krlcagledp rckleilwls dcdvtdegcs
      781 alasalisnp shltelilsr nklgdsgvkh lsavledphc klknlwlsyc gitdegcsal
      841 asalrsnpsh lreldlaenk irdlgvkhlc agledprckl eklwlrdccv tdegcsalas
      901 alrsnsshlr elnlsrnnlg psecrtlsiq lmvnkihyre tsqsqnqqrl ktqrhtasqr
      961 vktqghghig hlgrtk
//
LOCUS       XP_026128594             973 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X6
            [Carassius auratus].
ACCESSION   XP_026128594
VERSION     XP_026128594.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272809.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..973
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X6"
                     /calculated_mol_wt=109919
     Region          176..247
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          262..429
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          267..922
                     /region_name="NACHT"
                     /note="Predicted NTPase, NACHT family domain [Signal
                     transduction mechanisms]; COG5635"
                     /db_xref="CDD:444362"
     Region          <762..917
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          790..818
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          819..847
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          848..868
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          877..905
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..973
                     /gene="LOC113109177"
                     /coded_by="XM_026272809.1:44..2965"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 mghpvqfksg dtntdlssvq qerseaessc vsvrsdasmg hpvqfksgdt ntdlssvqqe
       61 rseaesscvs vrsnasmghp vqfksgdtnt dlricsqrss spdhscvslk sdrsmgnrpk
      121 lsdeavtsdp sradgersis ggvssvfcln ntsvtaslnk hdqavndelq rvkeqhktsm
      181 knkyerlceg lklqenesll nsiytqlyii egeregvnee hevlqmekta rtqpsqdapi
      241 ycndifkasa eagseekeqi ktvltkgiag igktvsvqkf ildwaegkan qdvdfmfvlp
      301 frelnlirdh qyslhrllld fhpelqdlds qiyeeckvvf ifdgldesri tlmfsdarkv
      361 cdvtetssva vlmsklmkge llpsaliwit srpaaanqip seyihrltei qgftepqkee
      421 yfrkrisdeh qasriishir rarslhimch ipvfcwisst vlqklleedl raeipqtlte
      481 myihflliqi nmrkqkyeer dpekllpsnr evivklaeva fkqlmegnvm fyeedliesg
      541 idvtdasvys gicteifkqe svihqrkvys fihlsvqefl aafylfycyl tenkktlhel
      601 ssytcdkvsl ydlltsavdk alksengrld lflrfllgvs lesnqrllqd llthtensse
      661 tisrttqdik erikssdhls adqsinlflc llevkdqtlf reiekflksd khtekklspa
      721 hcstisytiq mseepldeln lqkyntsaeg rrrlipaain crkavlwkcd gtdegcsalt
      781 salrsnpshl reldlsenki rdlgvkrlca gledprckle ilwlsdcdvt degcsalasa
      841 lisnpshlte lilsrnklgd sgvkhlsavl edphcklknl wlrdccvtde gcsalasalr
      901 snsshlreln lsrnnlgpse crtlsiqlmv nkihyretsq sqnqqrlktq rhtasqrvkt
      961 qghghighlg rtk
//
LOCUS       XP_026128595             973 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X7
            [Carassius auratus].
ACCESSION   XP_026128595
VERSION     XP_026128595.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272810.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..973
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X7"
                     /calculated_mol_wt=110113
     Region          176..247
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          262..429
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          511..571
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          573..702
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          686..>928
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          790..818
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     Region          819..847
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     Region          848..876
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     Region          877..905
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     CDS             1..973
                     /gene="LOC113109177"
                     /coded_by="XM_026272810.1:44..2965"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 mghpvqfksg dtntdlssvq qerseaessc vsvrsdasmg hpvqfksgdt ntdlssvqqe
       61 rseaesscvs vrsnasmghp vqfksgdtnt dlricsqrss spdhscvslk sdrsmgnrpk
      121 lsdeavtsdp sradgersis ggvssvfcln ntsvtaslnk hdqavndelq rvkeqhktsm
      181 knkyerlceg lklqenesll nsiytqlyii egeregvnee hevlqmekta rtqpsqdapi
      241 ycndifkasa eagseekeqi ktvltkgiag igktvsvqkf ildwaegkan qdvdfmfvlp
      301 frelnlirdh qyslhrllld fhpelqdlds qiyeeckvvf ifdgldesri tlmfsdarkv
      361 cdvtetssva vlmsklmkge llpsaliwit srpaaanqip seyihrltei qgftepqkee
      421 yfrkrisdeh qasriishir rarslhimch ipvfcwisst vlqklleedl raeipqtlte
      481 myihflliqi nmrkqkyeer dpekllpsnr evivklaeva fkqlmegnvm fyeedliesg
      541 idvtdasvys gicteifkqe svihqrkvys fihlsvqefl aafylfycyl tenkktlhel
      601 ssytcdkvsl ydlltsavdk alksengrld lflrfllgvs lesnqrllqd llthtensse
      661 tisrttqdik erikssdhls adqsinlflc llevkdqtlf reiekflksd khtekklspa
      721 hcstisytiq mseepldeln lqkyntsaeg rrrlipaain crkavlwkcd gtdegcsalt
      781 salrsnpshl reldlsenki rdlgvkrlca gledprckle ilwlsycgit degcsalasa
      841 lrsnpshlre ldlaenkird lgvkhlcagl edprcklekl wlrdccvtde gcsalasalr
      901 snsshlreln lsrnnlgpse crtlsiqlmv nkihyretsq sqnqqrlktq rhtasqrvkt
      961 qghghighlg rtk
//
LOCUS       XP_026128596             852 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X8
            [Carassius auratus].
ACCESSION   XP_026128596
VERSION     XP_026128596.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272811.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..852
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X8"
                     /calculated_mol_wt=97104
     Region          1..68
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          83..250
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          332..392
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          394..523
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          558..>807
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Region          611..639
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          640..668
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          669..689
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          698..726
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          727..755
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          756..780
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..852
                     /gene="LOC113109177"
                     /coded_by="XM_026272811.1:335..2893"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 mknkyerlce glklqenesl lnsiytqlyi iegeregvne ehevlqmekt artqpsqdap
       61 iycndifkas aeagseekeq iktvltkgia gigktvsvqk fildwaegka nqdvdfmfvl
      121 pfrelnlird hqyslhrlll dfhpelqdld sqiyeeckvv fifdgldesr itlmfsdark
      181 vcdvtetssv avlmsklmkg ellpsaliwi tsrpaaanqi pseyihrlte iqgftepqke
      241 eyfrkrisde hqasriishi rrarslhimc hipvfcwiss tvlqklleed lraeipqtlt
      301 emyihflliq inmrkqkyee rdpekllpsn revivklaev afkqlmegnv mfyeedlies
      361 gidvtdasvy sgicteifkq esvihqrkvy sfihlsvqef laafylfycy ltenkktlhe
      421 lssytcdkvs lydlltsavd kalksengrl dlflrfllgv slesnqrllq dllthtenss
      481 etisrttqdi kerikssdhl sadqsinlfl cllevkdqtl freiekflks dkhtekklsp
      541 ahcstisyti qmseepldel nlqkyntsae grrrlipaai ncrkavlwkc dgtdegcsal
      601 tsalrsnpsh lreldlsenk irdlgvkrlc agledprckl eilwlsdcdv tdegcsalas
      661 alisnpshlt elilsrnklg dsgvkhlsav ledphcklkn lwlsycgitd egcsalasal
      721 rsnpshlrel dlaenkirdl gvkhlcagle dprckleklw lrdccvtdeg csalasalrs
      781 nsshlrelnl srnnlgpsec rtlsiqlmvn kihyretsqs qnqqrlktqr htasqrvktq
      841 ghghighlgr tk
//
LOCUS       XP_026128597             765 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X9
            [Carassius auratus].
ACCESSION   XP_026128597
VERSION     XP_026128597.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272812.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..765
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X9"
                     /calculated_mol_wt=86881
     Region          176..247
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          262..429
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          511..571
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          573..702
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..765
                     /gene="LOC113109177"
                     /coded_by="XM_026272812.1:39..2336"
                     /db_xref="GeneID:113109177"
ORIGIN      
        1 mghpvqfksg dtntdlssvq qerseaessc vsvrsdasmg hpvqfksgdt ntdlssvqqe
       61 rseaesscvs vrsnasmghp vqfksgdtnt dlricsqrss spdhscvslk sdrsmgnrpk
      121 lsdeavtsdp sradgersis ggvssvfcln ntsvtaslnk hdqavndelq rvkeqhktsm
      181 knkyerlceg lklqenesll nsiytqlyii egeregvnee hevlqmekta rtqpsqdapi
      241 ycndifkasa eagseekeqi ktvltkgiag igktvsvqkf ildwaegkan qdvdfmfvlp
      301 frelnlirdh qyslhrllld fhpelqdlds qiyeeckvvf ifdgldesri tlmfsdarkv
      361 cdvtetssva vlmsklmkge llpsaliwit srpaaanqip seyihrltei qgftepqkee
      421 yfrkrisdeh qasriishir rarslhimch ipvfcwisst vlqklleedl raeipqtlte
      481 myihflliqi nmrkqkyeer dpekllpsnr evivklaeva fkqlmegnvm fyeedliesg
      541 idvtdasvys gicteifkqe svihqrkvys fihlsvqefl aafylfycyl tenkktlhel
      601 ssytcdkvsl ydlltsavdk alksengrld lflrfllgvs lesnqrllqd llthtensse
      661 tisrttqdik erikssdhls adqsinlflc llevkdqtlf reiekflksd khtekklspa
      721 hcstisytiq mseepldeln lqkyntsaeg rrrlipaain crkav
//
LOCUS       XP_026128598             983 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 12-like isoform X1
            [Carassius auratus].
ACCESSION   XP_026128598
VERSION     XP_026128598.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272813.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..983
                     /product="NACHT, LRR and PYD domains-containing protein
                     12-like isoform X1"
                     /calculated_mol_wt=111160
     Region          138..209
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          224..391
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          473..533
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          535..679
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          663..972
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Site            order(664,666,669,671,683,686,688,691,693,712,715,717,720,
                     722,740,742,745,747,766,769,771,774,776,795,798,800,803,
                     805,824,827,829,832,834,853,856,858,861,863,882,885,887,
                     890,892,911,914,916,919,921,940,943,945,948,950,969,972)
                     /site_type="active"
                     /note="Leucine-rich repeats [active]"
                     /db_xref="CDD:238064"
     Site            order(689..690,744,802,831,889,915,917,944)
                     /site_type="other"
                     /note="Substrate binding site [chemical binding]"
                     /db_xref="CDD:238064"
     Region          740..765
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          766..794
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          795..823
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          824..852
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          853..881
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          882..910
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          911..935
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..983
                     /gene="LOC113109178"
                     /coded_by="XM_026272813.1:412..3363"
                     /db_xref="GeneID:113109178"
ORIGIN      
        1 mgnkqtstdq efspgsssvd qkrseaessc vsvrsdrsmg hpvkfksgdt ktdlricsqr
       61 ssspdhscvs lksdesmgnp pklsdeavts dpsradgers isggvssvfc lnntsvtasl
      121 nkhdqavnde lqrvkeqhkt smknkyerlc eglklqenes llnsiytqly iiegeregvn
      181 eehevlqmek tartqhsqda piycndifka saeagseeke qiktvltkgi agigktvsvq
      241 kfildwaegk anqdvdfmfv lpfrelnlir dhqyslhrll ldfhpelqdl dsqiyeeckv
      301 vfifdgldes ritlmfsdaq kvcdvtetss vavlmsklmk gellpsaliw itsrpaaanq
      361 ipseyihrlt eiqgftepqk eeyfrkrisd ehqasriish irrarslhim chipvfcwis
      421 stvlqkllee dlraeipqtl temyihflli qinmrkqkye erdpekllps nrevivklae
      481 vafkqlmkgn vmfyeedlie ssidvtdasv ysgicteifk qesvihqrkv ysfihlsvqe
      541 flaafyllyc cltknkktlt efrsyryyfd sdedsesdsd evslydllts avdkalksdn
      601 ghldlflrfl lgvslesnqr llqdllthte nrpqtisrtt ryikekirdp ddshplsadq
      661 sinlflclle vkdqtlfrei qefvksdkhs eklsaahcst isymiqmsee pldeldpmky
      721 ntsdegrrrl ipavincrka vlrdcdvtde gcsaltsalr snpshlreln lsgnkirdlg
      781 vkclcagled phckleilgl sycdvtdegc saltsalrsn pshlreldls lnkirdsgvk
      841 rlcagledpr ckleilwlrd cgvtdegcsa lasalksnps hitllslsgn kirdsgvkhl
      901 cvgledphck leklwlsdcg vtdegcsalt salrsnpshl teldlsvnnl eksevkllsd
      961 lkddthykle rlyyrsvasr kfs
//
LOCUS       XP_026128599             918 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X2
            [Carassius auratus].
ACCESSION   XP_026128599
VERSION     XP_026128599.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272814.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..918
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X2"
                     /calculated_mol_wt=103378
     Region          138..208
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          219..386
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          463..523
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          525..665
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          597..907
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Site            order(597,600,602,616,619,621,624,626,644,650,652,655,657,
                     675,678,680,682,699,702,704,713,715,733,735,738,740,759,
                     762,764,767,769,788,791,793,796,798,817,820,822,825,827,
                     846,849,851,854,856,875,878,880,883,885,904,907)
                     /site_type="active"
                     /note="Leucine-rich repeats [active]"
                     /db_xref="CDD:238064"
     Site            order(622..623,737,766,824,850,852,879)
                     /site_type="other"
                     /note="Substrate binding site [chemical binding]"
                     /db_xref="CDD:238064"
     Region          731..758
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          759..787
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          788..816
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          817..845
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          846..874
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..918
                     /gene="LOC113109178"
                     /coded_by="XM_026272814.1:222..2978"
                     /db_xref="GeneID:113109178"
ORIGIN      
        1 medtqtstdq efspgcssvd qkrseaessc vsvrsdgsmd rpiefksgdt ktdlssvdqk
       61 rseaesscvs vrsdasmgqp iefksgdtkt dlssvdqkrs eaesscvsvr sdwsvnqsld
      121 yksedtktdp rhevlnrfrs nllkkferly egtamqrnpt llneiytely itesesgeis
      181 nehevrqiet qsrrtatedt aikcsdifrp lpgqdkairt vltkgvagig ktvsvqklil
      241 dwaegkenqd vqlifplpfr einlmkdktl slsdllhvff petkkmeiss dgykvlfifd
      301 gldecrlsld fksevkvcni sesasvdell mnlivgnllp saliwitsrp aaadlipsec
      361 vhrvtevrgf nepqkeeyfr krisdqslad riishlkssr slyimchipv fcwisaavle
      421 kilsraesge ipktltqmyt hflilqtnik hekdyekklt dedmilklgk vafqqlvkgn
      481 lifyeedlre cgidvteasv ysglctqifr eelglyqgkv fcfvhlsiqe hlaalyvhls
      541 wtnlnrnvfe siakqsllsk vkkpfqlsss ehvslselhq ravkealqsk nghldlflrf
      601 llglseeshq illqqimtlk rsssdsnett veyikkkirt ikspeksinl fhclnelgdr
      661 slvkeiqqyl tsggiketnl sssqwsavvf vlltseeeln efhldkfvkg knnpenmkvl
      721 qkllpvikes ksvqlnycgv tdegcsalts alrsnpshlr eldlsgnkir dsgvkrlcag
      781 ledprcklek lwlrdcgvtd egcsalasal ksnpshitll slsgnkirds gvkhlcvgle
      841 dphckleklw lsdcgvtdeg csaltsalrs npshlteldl svnnleksev kllsdlkddt
      901 hyklerlyyr svasrkfs
//
LOCUS       XP_026128600             907 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 12-like isoform X3
            [Carassius auratus].
ACCESSION   XP_026128600
VERSION     XP_026128600.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272815.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..907
                     /product="NACHT, LRR and PYD domains-containing protein
                     12-like isoform X3"
                     /calculated_mol_wt=102950
     Region          62..133
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          148..315
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          397..457
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          459..603
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          587..896
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Site            order(588,590,593,595,607,610,612,615,617,636,639,641,644,
                     646,664,666,669,671,690,693,695,698,700,719,722,724,727,
                     729,748,751,753,756,758,777,780,782,785,787,806,809,811,
                     814,816,835,838,840,843,845,864,867,869,872,874,893,896)
                     /site_type="active"
                     /note="Leucine-rich repeats [active]"
                     /db_xref="CDD:238064"
     Site            order(613..614,668,726,755,813,839,841,868)
                     /site_type="other"
                     /note="Substrate binding site [chemical binding]"
                     /db_xref="CDD:238064"
     Region          664..689
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          690..718
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          719..747
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          748..776
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          777..805
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          806..834
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          835..859
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..907
                     /gene="LOC113109178"
                     /coded_by="XM_026272815.1:698..3421"
                     /db_xref="GeneID:113109178"
ORIGIN      
        1 mgnppklsde avtsdpsrad gersisggvs svfclnntsv taslnkhdqa vndelqrvke
       61 qhktsmknky erlceglklq enesllnsiy tqlyiieger egvneehevl qmektartqh
      121 sqdapiycnd ifkasaeags eekeqiktvl tkgiagigkt vsvqkfildw aegkanqdvd
      181 fmfvlpfrel nlirdhqysl hrllldfhpe lqdldsqiye eckvvfifdg ldesritlmf
      241 sdaqkvcdvt etssvavlms klmkgellps aliwitsrpa aanqipseyi hrlteiqgft
      301 epqkeeyfrk risdehqasr iishirrars lhimchipvf cwisstvlqk lleedlraei
      361 pqtltemyih flliqinmrk qkyeerdpek llpsnreviv klaevafkql mkgnvmfyee
      421 dliessidvt dasvysgict eifkqesvih qrkvysfihl svqeflaafy llyccltknk
      481 ktltefrsyr yyfdsdedse sdsdevslyd lltsavdkal ksdnghldlf lrfllgvsle
      541 snqrllqdll thtenrpqti srttryikek irdpddshpl sadqsinlfl cllevkdqtl
      601 freiqefvks dkhseklsaa hcstisymiq mseepldeld pmkyntsdeg rrrlipavin
      661 crkavlrdcd vtdegcsalt salrsnpshl relnlsgnki rdlgvkclca gledphckle
      721 ilglsycdvt degcsaltsa lrsnpshlre ldlslnkird sgvkrlcagl edprckleil
      781 wlrdcgvtde gcsalasalk snpshitlls lsgnkirdsg vkhlcvgled phckleklwl
      841 sdcgvtdegc saltsalrsn pshlteldls vnnleksevk llsdlkddth yklerlyyrs
      901 vasrkfs
//
LOCUS       XP_026128601             880 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like isoform X4
            [Carassius auratus].
ACCESSION   XP_026128601
VERSION     XP_026128601.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272816.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..880
                     /product="NLR family CARD domain-containing protein 3-like
                     isoform X4"
                     /calculated_mol_wt=99333
     Region          100..170
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          181..348
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          425..485
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          487..627
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          559..869
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Site            order(559,562,564,578,581,583,586,588,606,612,614,617,619,
                     637,640,642,644,661,664,666,675,677,695,697,700,702,721,
                     724,726,729,731,750,753,755,758,760,779,782,784,787,789,
                     808,811,813,816,818,837,840,842,845,847,866,869)
                     /site_type="active"
                     /note="Leucine-rich repeats [active]"
                     /db_xref="CDD:238064"
     Site            order(584..585,699,728,786,812,814,841)
                     /site_type="other"
                     /note="Substrate binding site [chemical binding]"
                     /db_xref="CDD:238064"
     Region          693..720
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          721..749
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          750..778
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          779..807
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          808..836
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..880
                     /gene="LOC113109178"
                     /coded_by="XM_026272816.1:222..2864"
                     /db_xref="GeneID:113109178"
ORIGIN      
        1 medtqtstdq efspgcssvd qkrseaessc vsvrsdgsmd rpiefksgdt ktdlssvdqk
       61 rseaesscvs vrsdwsvnqs ldyksedtkt dprhevlnrf rsnllkkfer lyegtamqrn
      121 ptllneiyte lyitesesge isnehevrqi etqsrrtate dtaikcsdif rplpgqdkai
      181 rtvltkgvag igktvsvqkl ildwaegken qdvqlifplp freinlmkdk tlslsdllhv
      241 ffpetkkmei ssdgykvlfi fdgldecrls ldfksevkvc nisesasvde llmnlivgnl
      301 lpsaliwits rpaaadlips ecvhrvtevr gfnepqkeey frkrisdqsl adriishlks
      361 srslyimchi pvfcwisaav lekilsraes geipktltqm ythflilqtn ikhekdyekk
      421 ltdedmilkl gkvafqqlvk gnlifyeedl recgidvtea svysglctqi freelglyqg
      481 kvfcfvhlsi qehlaalyvh lswtnlnrnv fesiakqsll skvkkpfqls ssehvslsel
      541 hqravkealq sknghldlfl rfllglsees hqillqqimt lkrsssdsne ttveyikkki
      601 rtikspeksi nlfhclnelg drslvkeiqq yltsggiket nlsssqwsav vfvlltseee
      661 lnefhldkfv kgknnpenmk vlqkllpvik esksvqlnyc gvtdegcsal tsalrsnpsh
      721 lreldlsgnk irdsgvkrlc agledprckl eklwlrdcgv tdegcsalas alksnpshit
      781 llslsgnkir dsgvkhlcvg ledphcklek lwlsdcgvtd egcsaltsal rsnpshltel
      841 dlsvnnleks evkllsdlkd dthyklerly yrsvasrkfs
//
LOCUS       XP_026128602             842 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X5
            [Carassius auratus].
ACCESSION   XP_026128602
VERSION     XP_026128602.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272817.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..842
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X5"
                     /calculated_mol_wt=95099
     Region          62..132
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          143..310
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          387..447
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          449..589
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          521..831
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Site            order(521,524,526,540,543,545,548,550,568,574,576,579,581,
                     599,602,604,606,623,626,628,637,639,657,659,662,664,683,
                     686,688,691,693,712,715,717,720,722,741,744,746,749,751,
                     770,773,775,778,780,799,802,804,807,809,828,831)
                     /site_type="active"
                     /note="Leucine-rich repeats [active]"
                     /db_xref="CDD:238064"
     Site            order(546..547,661,690,748,774,776,803)
                     /site_type="other"
                     /note="Substrate binding site [chemical binding]"
                     /db_xref="CDD:238064"
     Region          655..682
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          683..711
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          712..740
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          741..769
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          770..798
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..842
                     /gene="LOC113109178"
                     /coded_by="XM_026272817.1:222..2750"
                     /db_xref="GeneID:113109178"
ORIGIN      
        1 medtqtstdq efspgcssvd qkrseaessc vsvrsdgsmd rpiefksgdt ktdlrhevln
       61 rfrsnllkkf erlyegtamq rnptllneiy telyiteses geisnehevr qietqsrrta
      121 tedtaikcsd ifrplpgqdk airtvltkgv agigktvsvq klildwaegk enqdvqlifp
      181 lpfreinlmk dktlslsdll hvffpetkkm eissdgykvl fifdgldecr lsldfksevk
      241 vcnisesasv dellmnlivg nllpsaliwi tsrpaaadli psecvhrvte vrgfnepqke
      301 eyfrkrisdq sladriishl kssrslyimc hipvfcwisa avlekilsra esgeipktlt
      361 qmythflilq tnikhekdye kkltdedmil klgkvafqql vkgnlifyee dlrecgidvt
      421 easvysglct qifreelgly qgkvfcfvhl siqehlaaly vhlswtnlnr nvfesiakqs
      481 llskvkkpfq lsssehvsls elhqravkea lqsknghldl flrfllglse eshqillqqi
      541 mtlkrsssds nettveyikk kirtikspek sinlfhclne lgdrslvkei qqyltsggik
      601 etnlsssqws avvfvlltse eelnefhldk fvkgknnpen mkvlqkllpv ikesksvqln
      661 ycgvtdegcs altsalrsnp shlreldlsg nkirdsgvkr lcagledprc kleklwlrdc
      721 gvtdegcsal asalksnpsh itllslsgnk irdsgvkhlc vgledphckl eklwlsdcgv
      781 tdegcsalts alrsnpshlt eldlsvnnle ksevkllsdl kddthykler lyyrsvasrk
      841 fs
//
LOCUS       XP_026128604             967 aa            linear   VRT 18-JUN-2025
DEFINITION  rab3 GTPase-activating protein catalytic subunit isoform X1
            [Carassius auratus].
ACCESSION   XP_026128604
VERSION     XP_026128604.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272819.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..967
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..967
                     /product="rab3 GTPase-activating protein catalytic subunit
                     isoform X1"
                     /calculated_mol_wt=108047
     Region          593..750
                     /region_name="Rab3-GTPase_cat"
                     /note="Rab3 GTPase-activating protein catalytic subunit;
                     pfam13890"
                     /db_xref="CDD:464022"
     Region          761..967
                     /region_name="Rab3-GAP_cat_C"
                     /note="Rab3 GTPase-activating protein catalytic subunit
                     C-terminal; pfam19533"
                     /db_xref="CDD:466115"
     CDS             1..967
                     /gene="rab3gap1"
                     /coded_by="XM_026272819.1:44..2947"
                     /db_xref="GeneID:113109180"
ORIGIN      
        1 mhlernkqra kmaadsdpes evfeitdftt asewerfisr veevlndwkl igsgvgkple
       61 kgeltsgswe ehtqeinfad frfsithhcl kqestenesr depeedaypl amqdllcmnn
      121 dfpprahclv rwfglreflv iapgahceav vseskcnlll ssvsialant gcqvpllvqi
      181 qqkwrkvyag ecqgpgvrtd femvhlrkap gqythlsgll difknkigcp ltplppisis
      241 irftfvlqdg qqcswpqqpp dfdallagev ggvefgklpf gacedpisel hlattwpnlt
      301 egivvdndvy sdldplqaph wsvrvrkadn pqcllgeflt effklccrke tseeilgrna
      361 vdeegkensd isqalsklte ptavpihkls vssmvhsark rirrnrrade spinndvlns
      421 illylfpdaa ldkadssevr ssqepardse dyhlynqlks apsdsltsrl alcvcvvnfh
      481 hggvravahl wqefvlemry rwenncliyg laggapdlrc cllhqklqml nccierkrar
      541 ddgrksgasd rsradvspgk swdswsdsed effeclsdte emketdsekr pankskaegr
      601 lqphgkltll rspeplyipv tqepapmted lleeqsevla klgtsaegah lrarmqsacl
      661 lsdmesfkaa npgccledfv rwysprdyve eevvdeagqt vtrgelsarm kipgnmwvea
      721 wetakatpar rqkrlfddtk eaekvlhyls qqkpsdltqh lmpcvlhaal lkikeeease
      781 diasvrkalq qvtahaskll rhpnpdfkkl ediiaqmsav eaviacsrsl knkfgiaggq
      841 reddtdelqr fvsclleepe vsvigagrgp agtiihklfv ssqrlvdssd eaallapmed
      901 eaahsggtdd rkavpdfppp agrevllrtc vprpapyska lpqrlfcvlt rdefrlagaf
      961 ssdtcff
//
LOCUS       XP_026128605             960 aa            linear   VRT 18-JUN-2025
DEFINITION  rab3 GTPase-activating protein catalytic subunit isoform X2
            [Carassius auratus].
ACCESSION   XP_026128605
VERSION     XP_026128605.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272820.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..960
                     /product="rab3 GTPase-activating protein catalytic subunit
                     isoform X2"
                     /calculated_mol_wt=107301
     Region          593..750
                     /region_name="Rab3-GTPase_cat"
                     /note="Rab3 GTPase-activating protein catalytic subunit;
                     pfam13890"
                     /db_xref="CDD:464022"
     Region          761..960
                     /region_name="Rab3-GAP_cat_C"
                     /note="Rab3 GTPase-activating protein catalytic subunit
                     C-terminal; pfam19533"
                     /db_xref="CDD:466115"
     CDS             1..960
                     /gene="rab3gap1"
                     /coded_by="XM_026272820.1:43..2925"
                     /db_xref="GeneID:113109180"
ORIGIN      
        1 mhlernkqra kmaadsdpes evfeitdftt asewerfisr veevlndwkl igsgvgkple
       61 kgeltsgswe ehtqeinfad frfsithhcl kqestenesr depeedaypl amqdllcmnn
      121 dfpprahclv rwfglreflv iapgahceav vseskcnlll ssvsialant gcqvpllvqi
      181 qqkwrkvyag ecqgpgvrtd femvhlrkap gqythlsgll difknkigcp ltplppisis
      241 irftfvlqdg qqcswpqqpp dfdallagev ggvefgklpf gacedpisel hlattwpnlt
      301 egivvdndvy sdldplqaph wsvrvrkadn pqcllgeflt effklccrke tseeilgrna
      361 vdeegkensd isqalsklte ptavpihkls vssmvhsark rirrnrrade spinndvlns
      421 illylfpdaa ldkadssevr ssqepardse dyhlynqlks apsdsltsrl alcvcvvnfh
      481 hggvravahl wqefvlemry rwenncliyg laggapdlrc cllhqklqml nccierkrar
      541 ddgrksgasd rsradvspgk swdswsdsed effeclsdte emketdsekr pankskaegr
      601 lqphgkltll rspeplyipv tqepapmted lleeqsevla klgtsaegah lrarmqsacl
      661 lsdmesfkaa npgccledfv rwysprdyve eevvdeagqt vtrgelsarm kipgnmwvea
      721 wetakatpar rqkrlfddtk eaekvlhyls qqkpsdltqh lmpcvlhaal lkikeeease
      781 diasvrkalq qvtahaskll rhpnpdfkkl ediiaqmsav eaviacsrsl knkfgiaggq
      841 reddtdelqr fvsclleepe vsvigagrgp agtiihklfv ssqraallap medeaahsgg
      901 tddrkavpdf pppagrevll rtcvprpapy skalpqrlfc vltrdefrla gafssdtcff
//
LOCUS       XP_026128606             927 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X1
            [Carassius auratus].
ACCESSION   XP_026128606
VERSION     XP_026128606.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272821.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..927
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..927
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X1"
                     /calculated_mol_wt=104986
     Region          159..229
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          240..407
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          484..544
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          546..682
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          671..>903
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          748..775
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          776..804
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          805..833
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          834..854
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          863..891
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..927
                     /gene="LOC113109181"
                     /coded_by="XM_026272821.1:52..2835"
                     /db_xref="GeneID:113109181"
ORIGIN      
        1 meirersssp dhtreslksh rsmnppessd dpvtsdpric sqrssspdhs cvslksdesm
       61 gnppnlsdea vtsdpricsq rssspdhscv slksdrsmrd ppklndeavt sdpssvhqkr
      121 seaesscvsv rsdvsmkesl dyksedtktd lrrevlnrfr snllkkfehl yegtatqrnp
      181 tllneiytel yitesesgei snehevrqie tqsrraated taikcsdifr plpgqdkair
      241 tvltkgvagi gktvsvqkli ldwtegkenq dvqfifplpf reinlmkdkt lslsdllhvf
      301 fpetkemeis sdeykvlfif dgldecrlsl dfkskvklcn isepasvdel lmnlivgnll
      361 psaliwitsr paaadlipse cvhrvtevrg fnepqkeeyf rkrisdqsla driishlkss
      421 rslyimchip vfcwisaavl ekmlsraerg eipktltqmy thflilqtni khekdyekkv
      481 tdqdmilklg kvafeqlvkg nlifyeedlr ecgidvteas vysglctqif reelglyqgk
      541 vfcfvhlsiq ehlaalyvhl swtnhnrnvf dqslwskvkk qfqlsssehv slselhqrav
      601 kealqskngh ldlflrfllg lsveshqill qqimtlkrss sdsneetvef ikkkirtids
      661 peksinlfhc lnelgdrslv keiqqylesg rikevnlsss qwsavvfvll tseeelnqfh
      721 ldkfvegkdk aenmkvlqkl lpvikesrsv qlrdcdvtde gcstlasalr snpshlreld
      781 ltgnkirdsg lkllcaglkd phckleklrl rdcgvtdegc saltsalrsn pshlrglsls
      841 wnkirdlgvk rlcavledpr ckleklglsd cgvtdegcsa lasalrsnps hlrylnltln
      901 nlgpsevkll sdlkddphyk letlycw
//
LOCUS       XP_026128607             905 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X2
            [Carassius auratus].
ACCESSION   XP_026128607
VERSION     XP_026128607.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272822.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..905
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X2"
                     /calculated_mol_wt=102492
     Region          138..209
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          224..391
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          473..533
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          535..667
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          651..>883
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          755..783
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          784..812
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          813..841
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          842..870
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          871..899
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..905
                     /gene="LOC113109181"
                     /coded_by="XM_026272822.1:394..3111"
                     /db_xref="GeneID:113109181"
ORIGIN      
        1 medtqtstdq efspgcssvd qkrseaessc vsvrsdgsmi hpenfksgdt ktvlricsqr
       61 ssspdhscvs lksdgsmrdp pklsdeavts dpsradgers vsggvssvfc lnntsvtasl
      121 nkhdqalnde lqrvkeqhkt smknkyerlc eglklqenes llnsiytqly iiegeregvn
      181 eehevlqmek tartqhsqda piycndifka saeagseeke qiktvltkgi agigktvsvq
      241 kfildwaegk anqdvdfmfv lpfrelnlir dhqyslhrll ldfhpelqdl dsqiyeeckv
      301 vfifdgldes ritlmfsdaq kvcdvtetss vavlmsklmk gellpsaliw itsrpaaanq
      361 ipseyihrlt eiqgftepqk eeyfrkrisd ehqasriish irrarslhim chipvfcwis
      421 stvlqkllee dlsaeipqtl temyihflli qinmrkqkye erdpekllps drevivklae
      481 vafkqlmkgn vmfyeedlie ssidvtdasv ysgicteifk aesvihqrkv ysfihlsvqe
      541 flaafylfyc yltenkktlh efslnrsdev slydlltsav dtalesengr ldlflrfllg
      601 vslesnqrll qdllthtens setisrttry ikerikddpe hhrlsadqsi nlflcllevk
      661 dqtlfreiqe fvksdkhsee klsaahcsti symlqmseep ldeldlekyn tsaegrrrli
      721 pavincrkal lrdcgvtdeg csaltsalrs npshlrelsl sgnkirdlgv kclcavledp
      781 rckleklwls dcgvtdegcs altsalrsnp shlrelslsv nkirdsgvkc lcagledphc
      841 kleklwlmrc dvtdegcsal tsalrsnpsh mreldlslnk igdsevklls dlkadpcykl
      901 etlyc
//
LOCUS       XP_026128608             904 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X3
            [Carassius auratus].
ACCESSION   XP_026128608
VERSION     XP_026128608.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272823.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..904
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X3"
                     /calculated_mol_wt=102405
     Region          52..>547
                     /region_name="NACHT"
                     /note="Predicted NTPase, NACHT family domain [Signal
                     transduction mechanisms]; COG5635"
                     /db_xref="CDD:444362"
     Region          137..208
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          223..390
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          534..666
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          650..>882
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          754..782
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          783..811
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          812..840
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          841..869
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          870..898
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..904
                     /gene="LOC113109181"
                     /coded_by="XM_026272823.1:396..3110"
                     /db_xref="GeneID:113109181"
ORIGIN      
        1 medtqtstdq efspgcssvd qkrseaessc vsvrsdgsmi hpenfksgdt ktvlricsqr
       61 ssspdhscvs lksdgsmrdp pklsdeavts dpradgersv sggvssvfcl nntsvtasln
      121 khdqalndel qrvkeqhkts mknkyerlce glklqenesl lnsiytqlyi iegeregvne
      181 ehevlqmekt artqhsqdap iycndifkas aeagseekeq iktvltkgia gigktvsvqk
      241 fildwaegka nqdvdfmfvl pfrelnlird hqyslhrlll dfhpelqdld sqiyeeckvv
      301 fifdgldesr itlmfsdaqk vcdvtetssv avlmsklmkg ellpsaliwi tsrpaaanqi
      361 pseyihrlte iqgftepqke eyfrkrisde hqasriishi rrarslhimc hipvfcwiss
      421 tvlqklleed lsaeipqtlt emyihflliq inmrkqkyee rdpekllpsd revivklaev
      481 afkqlmkgnv mfyeedlies sidvtdasvy sgicteifka esvihqrkvy sfihlsvqef
      541 laafylfycy ltenkktlhe fslnrsdevs lydlltsavd talesengrl dlflrfllgv
      601 slesnqrllq dllthtenss etisrttryi kerikddpeh hrlsadqsin lflcllevkd
      661 qtlfreiqef vksdkhseek lsaahcstis ymlqmseepl deldlekynt saegrrrlip
      721 avincrkall rdcgvtdegc saltsalrsn pshlrelsls gnkirdlgvk clcavledpr
      781 ckleklwlsd cgvtdegcsa ltsalrsnps hlrelslsvn kirdsgvkcl cagledphck
      841 leklwlmrcd vtdegcsalt salrsnpshm reldlslnki gdsevkllsd lkadpcykle
      901 tlyc
//
LOCUS       XP_026128609             867 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X4
            [Carassius auratus].
ACCESSION   XP_026128609
VERSION     XP_026128609.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272824.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..867
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X4"
                     /calculated_mol_wt=98410
     Region          100..171
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          186..353
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          435..495
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          497..629
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          613..>845
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          717..745
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          746..774
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          775..803
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          804..832
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          833..861
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..867
                     /gene="LOC113109181"
                     /coded_by="XM_026272824.1:395..2998"
                     /db_xref="GeneID:113109181"
ORIGIN      
        1 medtqtstdq efspgcrics qrssspdhsc vslksdgsmr dppklsdeav tsdpsradge
       61 rsvsggvssv fclnntsvta slnkhdqaln delqrvkeqh ktsmknkyer lceglklqen
      121 esllnsiytq lyiiegereg vneehevlqm ektartqhsq dapiycndif kasaeagsee
      181 keqiktvltk giagigktvs vqkfildwae gkanqdvdfm fvlpfrelnl irdhqyslhr
      241 llldfhpelq dldsqiyeec kvvfifdgld esritlmfsd aqkvcdvtet ssvavlmskl
      301 mkgellpsal iwitsrpaaa nqipseyihr lteiqgftep qkeeyfrkri sdehqasrii
      361 shirrarslh imchipvfcw isstvlqkll eedlsaeipq tltemyihfl liqinmrkqk
      421 yeerdpekll psdrevivkl aevafkqlmk gnvmfyeedl iessidvtda svysgictei
      481 fkaesvihqr kvysfihlsv qeflaafylf ycyltenkkt lhefslnrsd evslydllts
      541 avdtalesen grldlflrfl lgvslesnqr llqdllthte nssetisrtt ryikerikdd
      601 pehhrlsadq sinlflclle vkdqtlfrei qefvksdkhs eeklsaahcs tisymlqmse
      661 epldeldlek yntsaegrrr lipavincrk allrdcgvtd egcsaltsal rsnpshlrel
      721 slsgnkirdl gvkclcavle dprckleklw lsdcgvtdeg csaltsalrs npshlrelsl
      781 svnkirdsgv kclcagledp hckleklwlm rcdvtdegcs altsalrsnp shmreldlsl
      841 nkigdsevkl lsdlkadpcy kletlyc
//
LOCUS       XP_026128610             866 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like isoform X5
            [Carassius auratus].
ACCESSION   XP_026128610
VERSION     XP_026128610.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272825.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..866
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like isoform X5"
                     /calculated_mol_wt=98323
     Region          17..>509
                     /region_name="NACHT"
                     /note="Predicted NTPase, NACHT family domain [Signal
                     transduction mechanisms]; COG5635"
                     /db_xref="CDD:444362"
     Region          99..170
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          185..352
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          496..628
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          612..>844
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          716..744
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          745..773
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          774..802
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          803..831
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     Region          832..860
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275381"
     CDS             1..866
                     /gene="LOC113109181"
                     /coded_by="XM_026272825.1:399..2999"
                     /db_xref="GeneID:113109181"
ORIGIN      
        1 medtqtstdq efspgcrics qrssspdhsc vslksdgsmr dppklsdeav tsdpradger
       61 svsggvssvf clnntsvtas lnkhdqalnd elqrvkeqhk tsmknkyerl ceglklqene
      121 sllnsiytql yiiegeregv neehevlqme ktartqhsqd apiycndifk asaeagseek
      181 eqiktvltkg iagigktvsv qkfildwaeg kanqdvdfmf vlpfrelnli rdhqyslhrl
      241 lldfhpelqd ldsqiyeeck vvfifdglde sritlmfsda qkvcdvtets svavlmsklm
      301 kgellpsali witsrpaaan qipseyihrl teiqgftepq keeyfrkris dehqasriis
      361 hirrarslhi mchipvfcwi sstvlqklle edlsaeipqt ltemyihfll iqinmrkqky
      421 eerdpekllp sdrevivkla evafkqlmkg nvmfyeedli essidvtdas vysgicteif
      481 kaesvihqrk vysfihlsvq eflaafylfy cyltenkktl hefslnrsde vslydlltsa
      541 vdtaleseng rldlflrfll gvslesnqrl lqdllthten ssetisrttr yikerikddp
      601 ehhrlsadqs inlflcllev kdqtlfreiq efvksdkhse eklsaahcst isymlqmsee
      661 pldeldleky ntsaegrrrl ipavincrka llrdcgvtde gcsaltsalr snpshlrels
      721 lsgnkirdlg vkclcavled prckleklwl sdcgvtdegc saltsalrsn pshlrelsls
      781 vnkirdsgvk clcagledph ckleklwlmr cdvtdegcsa ltsalrsnps hmreldlsln
      841 kigdsevkll sdlkadpcyk letlyc
//
LOCUS       XP_026128611             874 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109182 isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128611
VERSION     XP_026128611.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272826.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..874
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..874
                     /product="uncharacterized protein LOC113109182 isoform X1"
                     /calculated_mol_wt=99418
     Region          163..>196
                     /region_name="Bbox1"
                     /note="B-box-type 1 zinc finger (Bbox1); cd19757"
                     /db_xref="CDD:380815"
     Region          227..331
                     /region_name="CxC3"
                     /note="CxC3 like cysteine cluster associated with KDZ
                     transposases; pfam18804"
                     /db_xref="CDD:408575"
     Region          378..598
                     /region_name="KDZ"
                     /note="Kyakuja-Dileera-Zisupton transposase; pfam18758"
                     /db_xref="CDD:465857"
     Region          582..>714
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     CDS             1..874
                     /gene="LOC113109182"
                     /coded_by="XM_026272826.1:1687..4311"
                     /db_xref="GeneID:113109182"
ORIGIN      
        1 msdhsnfeqv ldeldelveh selnyelqsl ddfinkmsge qeaapstshq pvrwlkrdsd
       61 gnvvydrprs srnqmashsy srkagahprm ldsycppdtv etfleelnhs qgddlddqet
      121 apapprassd wstrksllse rwekeraclv ntmvaqqnvt tqicqqcgis paavrcrdcr
      181 pqpffcadcd vsihrnhvfh nrdatiagff qplppttcvv eralsqcvci vllempkkic
      241 scspgslsvn tgkvvavvtm ngrydlsmpe mkceackttw spgvddlvrn dywpatlhfs
      301 tvdstdvfys yeelkmaapg lscqaflrml dqrtlrfgri gkikadsfrk sfleweavrf
      361 evdkicreeh fvcpactpdm lavsvdgnrk hyrfknaars eekalfdgif iakddeverf
      421 vdyihsttnh vsgrgvcggk wsaaretsqk ssskideegl elavcrhgvf ltalnmfrge
      481 iyayplylqn klantpisff amdvtckywp ylnkvtkscp elqhllsmkp flsvfhakah
      541 dfkcevkwsg ayqqgagltl geeveqcnaf lsriavttkh mskagrtdkl tlmamrwnqq
      601 kfnnlatsla cryqkatkrl esqlqdlesm riqlavtqve vegwvtdike waeattsqkn
      661 adldavinri evlvasikrr sqrlykdtdg skgrarirrk ireekailss vvekynsmvp
      721 dteriafdii lsdetvwpwq lshgdavdlk tkrkafdvvm avrrleeekk ivlsemakhw
      781 kslstradtl kemscqlsse alkselwdln eegikgflsl tlrkkqevtr mmkhardcya
      841 kvltgtsmdf qndwdgydsd selsdefdel ssek
//
LOCUS       XP_026128612             869 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109182 isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128612
VERSION     XP_026128612.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272827.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..869
                     /product="uncharacterized protein LOC113109182 isoform X2"
                     /calculated_mol_wt=98890
     Region          163..>196
                     /region_name="Bbox1"
                     /note="B-box-type 1 zinc finger (Bbox1); cd19757"
                     /db_xref="CDD:380815"
     Region          227..331
                     /region_name="CxC3"
                     /note="CxC3 like cysteine cluster associated with KDZ
                     transposases; pfam18804"
                     /db_xref="CDD:408575"
     Region          378..598
                     /region_name="KDZ"
                     /note="Kyakuja-Dileera-Zisupton transposase; pfam18758"
                     /db_xref="CDD:465857"
     Region          582..>714
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     CDS             1..869
                     /gene="LOC113109182"
                     /coded_by="XM_026272827.1:1687..4296"
                     /db_xref="GeneID:113109182"
ORIGIN      
        1 msdhsnfeqv ldeldelveh selnyelqsl ddfinkmsge qeaapstshq pvrwlkrdsd
       61 gnvvydrprs srnqmashsy srkagahprm ldsycppdtv etfleelnhs qgddlddqet
      121 apapprassd wstrksllse rwekeraclv ntmvaqqnvt tqicqqcgis paavrcrdcr
      181 pqpffcadcd vsihrnhvfh nrdatiagff qplppttcvv eralsqcvci vllempkkic
      241 scspgslsvn tgkvvavvtm ngrydlsmpe mkceackttw spgvddlvrn dywpatlhfs
      301 tvdstdvfys yeelkmaapg lscqaflrml dqrtlrfgri gkikadsfrk sfleweavrf
      361 evdkicreeh fvcpactpdm lavsvdgnrk hyrfknaars eekalfdgif iakddeverf
      421 vdyihsttnh vsgrgvcggk wsaaretsqk ssskideegl elavcrhgvf ltalnmfrge
      481 iyayplylqn klantpisff amdvtckywp ylnkvtkscp elqhllsmkp flsvfhakah
      541 dfkcevkwsg ayqqgagltl geeveqcnaf lsriavttkh mskagrtdkl tlmamrwnqq
      601 kfnnlatsla cryqkatkrl esqlqdlesm riqlavtqve vegwvtdike waeattsqkn
      661 adldavinri evlvasikrr sqrlykdtdg skgrarirrk ireekailss vvekynsmvp
      721 dteriafdii lsdetvwpwq lshgdavdlk tkrkafdvvm avrrleeekk ivlsemakhw
      781 kslstradtl kemscqlsse lwdlneegik gflsltlrkk qevtrmmkha rdcyakvltg
      841 tsmdfqndwd gydsdselsd efdelssek
//
LOCUS       XP_026128614             838 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109182 isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128614
VERSION     XP_026128614.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272829.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..838
                     /product="uncharacterized protein LOC113109182 isoform X3"
                     /calculated_mol_wt=95140
     Region          127..>160
                     /region_name="Bbox1"
                     /note="B-box-type 1 zinc finger (Bbox1); cd19757"
                     /db_xref="CDD:380815"
     Region          191..295
                     /region_name="CxC3"
                     /note="CxC3 like cysteine cluster associated with KDZ
                     transposases; pfam18804"
                     /db_xref="CDD:408575"
     Region          342..562
                     /region_name="KDZ"
                     /note="Kyakuja-Dileera-Zisupton transposase; pfam18758"
                     /db_xref="CDD:465857"
     Region          546..>678
                     /region_name="YhaN"
                     /note="Uncharacterized conserved protein YhaN, contains
                     AAA domain [Function unknown]; COG4717"
                     /db_xref="CDD:443752"
     CDS             1..838
                     /gene="LOC113109182"
                     /coded_by="XM_026272829.1:635..3151"
                     /db_xref="GeneID:113109182"
ORIGIN      
        1 msgeqeaaps tshqpvrwlk rdsdgnvvyd rprssrnqma shsysrkaga hprmldsycp
       61 pdtvetflee lnhsqgddld dqetapappr assdwstrks llserweker aclvntmvaq
      121 qnvttqicqq cgispaavrc rdcrpqpffc adcdvsihrn hvfhnrdati agffqplppt
      181 tcvveralsq cvcivllemp kkicscspgs lsvntgkvva vvtmngrydl smpemkceac
      241 kttwspgvdd lvrndywpat lhfstvdstd vfysyeelkm aapglscqaf lrmldqrtlr
      301 fgrigkikad sfrksflewe avrfevdkic reehfvcpac tpdmlavsvd gnrkhyrfkn
      361 aarseekalf dgifiakdde verfvdyihs ttnhvsgrgv cggkwsaare tsqkssskid
      421 eeglelavcr hgvfltalnm frgeiyaypl ylqnklantp isffamdvtc kywpylnkvt
      481 kscpelqhll smkpflsvfh akahdfkcev kwsgayqqga gltlgeeveq cnaflsriav
      541 ttkhmskagr tdkltlmamr wnqqkfnnla tslacryqka tkrlesqlqd lesmriqlav
      601 tqvevegwvt dikewaeatt sqknadldav inrievlvas ikrrsqrlyk dtdgskgrar
      661 irrkireeka ilssvvekyn smvpdteria fdiilsdetv wpwqlshgda vdlktkrkaf
      721 dvvmavrrle eekkivlsem akhwkslstr adtlkemscq lssealksel wdlneegikg
      781 flsltlrkkq evtrmmkhar dcyakvltgt smdfqndwdg ydsdselsde fdelssek
//
LOCUS       XP_026128615             866 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like [Carassius
            auratus].
ACCESSION   XP_026128615
VERSION     XP_026128615.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272830.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..866
                     /product="NLR family CARD domain-containing protein
                     3-like"
                     /calculated_mol_wt=98534
     Region          278..349
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          364..531
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          613..673
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          675..804
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..866
                     /gene="LOC113109183"
                     /coded_by="XM_026272830.1:27..2627"
                     /db_xref="GeneID:113109183"
ORIGIN      
        1 mtrirlcvei esklsiltec nftfrrlknc rknlitascq svimeirers sspdhtresl
       61 kshrsmnppe ssddpvtsdp ricsqrsssp dhsyvslksd gsmidppkls deavtsdpri
      121 csqrssspdh syvslksdgs mfdppklsde avtsdprics qrssspdhsy vslksdgsmi
      181 dppklsdeav tsdpricsqr ssspdhscvs lksdgsmidp pklsdeavts dpsradgers
      241 vsggvssvfc lnntsvtasl nkhdqavnde lqrvkeqhkt smknkyerlc eglklqenes
      301 llnsiytqly iiegeregvn eehevlqmek tartqpsqda piycndifka saeagseeke
      361 qiktvltkgi agigktvsvq kfildwaegk anqdvdfmfv lpfrelnlir dhqyslhrll
      421 ldfhpelqdl dsqiyeeckv vfifdgldes ritlmfsdaq kvcdvtetss vavlmsklmk
      481 gellpsaliw itsrpaaanq ipseyihrlt eiqgftepqk eeyfrkrisd ehqasriish
      541 irrarslhim chipvfcwis stvlqkllee dlraeipqtl temyihflli qinmrkqkye
      601 erdpekllps nrevivklae vafkqlmkgn vmfyeedlie ssidvtdasv ysgicteifk
      661 qesvihqrkv ysfihlsvqe flaafylfyc yltkdkktlr efrlyrsvkv slydlltsav
      721 dktlksengr ldlflrfllg vslesnqrll qdllkhtens setisrttqd ikdeikeedd
      781 lsadqsinlf lcllevkdqt lfreiqefvk sdkhseklsp ahcstisyml qmseepldel
      841 nlqkyntsvv grrrlipavi nckkav
//
LOCUS       XP_026128616             806 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109184 [Carassius auratus].
ACCESSION   XP_026128616
VERSION     XP_026128616.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272831.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..806
                     /product="uncharacterized protein LOC113109184"
                     /calculated_mol_wt=90909
     CDS             1..806
                     /gene="LOC113109184"
                     /coded_by="XM_026272831.1:153..2573"
                     /db_xref="GeneID:113109184"
ORIGIN      
        1 mkdtnledsd elfdstpess ddyvpdttse sdsdvsltln qakrrlldel didqsgsvsc
       61 pdcdtttsdk mhnvaseasg tgeepsssqn ttdgivvsay qkrdgarvyn krhyclycsk
      121 pyakmarhle sshenksdva ralsfpkgsk erknqldyir nrgnyahnaa vmesgkgelv
      181 pfkrprkevq gedfmhcayc qglftrkvlw rhmrtcrlqp qsdppkpgkn rvqsmctytg
      241 pvpsnmtkql wgvisamnpd pitdiikndr vitdigqhll nkgglsdknk qcvrekmrel
      301 grlihnarkv tslktledcv npkkymetvk avkytcgyds etdkflipsl anklgnslvk
      361 vckllkaqgl isndkqlvkn asefqevhan kwnemisata lrnireakwn vptlmpfted
      421 vqklhtflsq vqdewfnlls espstkawme lakvclaqmi lfnwrregev asmplsvfls
      481 rdtsdphedv dwalsevekk lcrhftrvit rgkrgrpvpv lltpkmlcsl ellvkqreac
      541 gvlkdnaymf arpeamthfr gsdclrgfak acgakcpkal tstrlrkhaa tlstvlnmtd
      601 temdqlanfl ghdirihref yrlpektlql akiskvlmal eqgrlaefhg knldeigidp
      661 dekvvdcdee eqvndcdeed rsiqeghcss tvdasaeval paternmshk rgkpssevpm
      721 ssgasamrpt ckgkssqkka pwqqaevqav erhlksfiis gtvpaksdce kclkaepqal
      781 rnrdwktvkf yvynritafk kklqcr
//
LOCUS       XP_026128617             800 aa            linear   VRT 18-JUN-2025
DEFINITION  neuroligin-4, X-linked-like [Carassius auratus].
ACCESSION   XP_026128617
VERSION     XP_026128617.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272832.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..800
                     /product="neuroligin-4, X-linked-like"
                     /calculated_mol_wt=89987
     Region          28..572
                     /region_name="COesterase"
                     /note="Carboxylesterase family; pfam00135"
                     /db_xref="CDD:395084"
     Site            order(156..158,235..237,240,384,388..389,426,472,475)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:238191"
     Site            order(236,357,471)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238191"
     CDS             1..800
                     /gene="LOC113109185"
                     /coded_by="XM_026272832.1:185..2587"
                     /db_xref="GeneID:113109185"
ORIGIN      
        1 mlrvrmilqv vsvvwgvtlv vceqaqfttv stnygklrgl rvalaseilg pveqylgvpy
       61 amaptgerrf qapeppaswp girnatqfap vcpqyledrl lltdmlpvwf tanldtvaty
      121 vheqsedcly lniyvpteee ahedtglkpv mvyihggsyv egtgnmmdgs vlasyghviv
      181 vtvnyrlgvl gflstgdqaa kgnyglldqi qalrwvkeni qafngdperv tifgsgagas
      241 cvslltlshy sedlfqkaii qsgtalsswa vnyqpakytr mlaekvgcne ddtveliecl
      301 qnknykelie qnitpskyhi afgpvidgdv ipddpqilme qgeflnydim lgvnqgegyk
      361 fvdgildsed ritsndfefa isefvdhlyg ypegkdtlre tikfmytdwa drenpemrrk
      421 tlvalftdhq wvapavatad lhaqygspty fyafyhhcqs dmkpawadsa hgdelpyvfg
      481 ipmigptdlf ncnfskndim lsavvmtywt nfaktgdpnq pvpqdtkfih tkpnrfeeva
      541 wskynpkdql ylhiglkprv rdhyratkia fwlelvphlh sinelfqyvs sttkippqdt
      601 tpfsytkrls nkllpsttrh ppappantkq mseqqktseh gdgtviievr dystelsvti
      661 avgasllfln ilafaalyyk kdkhrlelsr rhspprnltn diprvpseef mplqmkqlsh
      721 dhdcdslqgh dmiqltcppd ytlalrrspd dmplmtpnti tmiprsfadl ppsyhnpfna
      781 fgnstpssmg lphghsttrv
//
LOCUS       XP_026128618             798 aa            linear   VRT 18-JUN-2025
DEFINITION  inactive dipeptidyl peptidase 10 isoform X1 [Carassius auratus].
ACCESSION   XP_026128618
VERSION     XP_026128618.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272833.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..798
                     /product="inactive dipeptidyl peptidase 10 isoform X1"
                     /calculated_mol_wt=90619
     Region          135..502
                     /region_name="DPPIV_N"
                     /note="Dipeptidyl peptidase IV (DPP IV) N-terminal region;
                     pfam00930"
                     /db_xref="CDD:395744"
     Region          581..783
                     /region_name="Peptidase_S9"
                     /note="Prolyl oligopeptidase family; pfam00326"
                     /db_xref="CDD:459761"
     CDS             1..798
                     /gene="LOC113109186"
                     /coded_by="XM_026272833.1:85..2481"
                     /db_xref="GeneID:113109186"
ORIGIN      
        1 mnqtasvshq vkcqssssks itdlagmsap qrnwkgiaia llvilavcsl itlsvilltp
       61 vdtqpssdtk ltvedlfsad fyihdpearw indseviyrn hhghvirfni ltneteivlk
      121 nttfdtfkat rysispdmky vlfaynvkqv yrhsftasyi lysihtrevl qldppevlns
      181 klqhaawgvq gqqlvyifen niyyqsdvrs nslrltssgk enviyngiad wlyeeevlht
      241 hvahwwspdg erlaflvlnd slvpnmplpt ftgstypkgk qypypkagqp npmvkvfvvn
      301 lygpthtlel tppdefklre hyvvmvkwis ktktavrwln rpqnisiltv cdsttgacik
      361 rheetsdvwl srqnqepffs rdgsrffltv pvkqggrgdf qhvamftsqa radqnelrhl
      421 tsgnwevtqi laydensqsi fflstegsss rrqlfsvstv glfprqcltc elnkahctff
      481 sadfspanqh vllhckgpga ptvfihtlnt anyyvlennf vlraalrykr iqlleyrsvq
      541 tdhfelplki syppdfsesr tyalllmidt apggqqvndr ysldwdsvlv ssdnvivarl
      601 dgrgsgfqgq kvlqevhrrl gsvelqdqll aveyllklpy idrtrigvfg rgyggyvall
      661 likstenlfk caaavspvtd wslyasafse rylcfplqdd sryqfssvlq npqgfreqtl
      721 mllhatadan vhfqhtaeli knlvkvgany tlqiypdegh flskssqrha astlssyfrs
      781 clqedmlpis eeeeeeee
//
LOCUS       XP_026128619             793 aa            linear   VRT 18-JUN-2025
DEFINITION  inactive dipeptidyl peptidase 10 isoform X2 [Carassius auratus].
ACCESSION   XP_026128619
VERSION     XP_026128619.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272834.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..793
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..793
                     /product="inactive dipeptidyl peptidase 10 isoform X2"
                     /calculated_mol_wt=90268
     Region          130..497
                     /region_name="DPPIV_N"
                     /note="Dipeptidyl peptidase IV (DPP IV) N-terminal region;
                     pfam00930"
                     /db_xref="CDD:395744"
     Region          576..778
                     /region_name="Peptidase_S9"
                     /note="Prolyl oligopeptidase family; pfam00326"
                     /db_xref="CDD:459761"
     CDS             1..793
                     /gene="LOC113109186"
                     /coded_by="XM_026272834.1:266..2647"
                     /db_xref="GeneID:113109186"
ORIGIN      
        1 mtatkeqqsq rpnpqdedla gmsapqrnwk giaiallvil avcslitlsv illtpvdtqp
       61 ssdtkltved lfsadfyihd pearwindse viyrnhhghv irfniltnet eivlknttfd
      121 tfkatrysis pdmkyvlfay nvkqvyrhsf tasyilysih trevlqldpp evlnsklqha
      181 awgvqgqqlv yifenniyyq sdvrsnslrl tssgkenviy ngiadwlyee evlhthvahw
      241 wspdgerlaf lvlndslvpn mplptftgst ypkgkqypyp kagqpnpmvk vfvvnlygpt
      301 htleltppde fklrehyvvm vkwisktkta vrwlnrpqni siltvcdstt gacikrheet
      361 sdvwlsrqnq epffsrdgsr ffltvpvkqg grgdfqhvam ftsqaradqn elrhltsgnw
      421 evtqilayde nsqsifflst egsssrrqlf svstvglfpr qcltcelnka hctffsadfs
      481 panqhvllhc kgpgaptvfi htlntanyyv lennfvlraa lrykriqlle yrsvqtdhfe
      541 lplkisyppd fsesrtyall lmidtapggq qvndrysldw dsvlvssdnv ivarldgrgs
      601 gfqgqkvlqe vhrrlgsvel qdqllaveyl lklpyidrtr igvfgrgygg yvalllikst
      661 enlfkcaaav spvtdwslya safserylcf plqddsryqf ssvlqnpqgf reqtlmllha
      721 tadanvhfqh taeliknlvk vganytlqiy pdeghflsks sqrhaastls syfrsclqed
      781 mlpiseeeee eee
//
LOCUS       XP_026128620             792 aa            linear   VRT 18-JUN-2025
DEFINITION  inactive dipeptidyl peptidase 10 isoform X3 [Carassius auratus].
ACCESSION   XP_026128620
VERSION     XP_026128620.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272835.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..792
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..792
                     /product="inactive dipeptidyl peptidase 10 isoform X3"
                     /calculated_mol_wt=90077
     Region          129..496
                     /region_name="DPPIV_N"
                     /note="Dipeptidyl peptidase IV (DPP IV) N-terminal region;
                     pfam00930"
                     /db_xref="CDD:395744"
     Region          575..777
                     /region_name="Peptidase_S9"
                     /note="Prolyl oligopeptidase family; pfam00326"
                     /db_xref="CDD:459761"
     CDS             1..792
                     /gene="LOC113109186"
                     /coded_by="XM_026272835.1:392..2770"
                     /db_xref="GeneID:113109186"
ORIGIN      
        1 mtphylphms pasvtqdlag msapqrnwkg iaiallvila vcslitlsvi lltpvdtqps
       61 sdtkltvedl fsadfyihdp earwindsev iyrnhhghvi rfniltnete ivlknttfdt
      121 fkatrysisp dmkyvlfayn vkqvyrhsft asyilysiht revlqldppe vlnsklqhaa
      181 wgvqgqqlvy ifenniyyqs dvrsnslrlt ssgkenviyn giadwlyeee vlhthvahww
      241 spdgerlafl vlndslvpnm plptftgsty pkgkqypypk agqpnpmvkv fvvnlygpth
      301 tleltppdef klrehyvvmv kwisktktav rwlnrpqnis iltvcdsttg acikrheets
      361 dvwlsrqnqe pffsrdgsrf fltvpvkqgg rgdfqhvamf tsqaradqne lrhltsgnwe
      421 vtqilayden sqsifflste gsssrrqlfs vstvglfprq cltcelnkah ctffsadfsp
      481 anqhvllhck gpgaptvfih tlntanyyvl ennfvlraal rykriqlley rsvqtdhfel
      541 plkisyppdf sesrtyalll midtapggqq vndrysldwd svlvssdnvi varldgrgsg
      601 fqgqkvlqev hrrlgsvelq dqllaveyll klpyidrtri gvfgrgyggy valllikste
      661 nlfkcaaavs pvtdwslyas afserylcfp lqddsryqfs svlqnpqgfr eqtlmllhat
      721 adanvhfqht aeliknlvkv ganytlqiyp deghflskss qrhaastlss yfrsclqedm
      781 lpiseeeeee ee
//
LOCUS       XP_026128622             786 aa            linear   VRT 18-JUN-2025
DEFINITION  protein NLRC3-like [Carassius auratus].
ACCESSION   XP_026128622
VERSION     XP_026128622.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272837.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..786
                     /product="protein NLRC3-like"
                     /calculated_mol_wt=89329
     Region          197..268
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          283..450
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          532..592
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          594..723
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..786
                     /gene="LOC113109187"
                     /coded_by="XM_026272837.1:126..2486"
                     /db_xref="GeneID:113109187"
ORIGIN      
        1 meirersssp dhtreslksh rsmnppessd dpvtsdpric sqrssspdhs yvsmksdesm
       61 ghppnlsdea vtsdpricsq rssspdhsyv smksdesmgh ppnlsdeavt sdpricsqrs
      121 sspddscvsl ksdasmgppp klsdeavtsd psradgersi sggvssvfcl nntsvtasln
      181 khdqavndel qrvkeqhkts mknkcerlce glklqenesl lnsiytqlyi iegeregvne
      241 ehevlqmekt artqhsqdtp iycndifkas aeagseekeq iktvltkgia gigktvsvqk
      301 fildwaegka nqdvdfmfvl pfrelnlird hqyslhrlll dfhpelqdld sqiyeeckvv
      361 fifdgldesr itlmfsdaqk vcdvtetssv avlmsklmkg ellpsaliwi tsrpaaanqi
      421 pseyihrlte iqgftepqke eyfrkrisde hqasriishi rrarslhimc hipvfcwiss
      481 tvlqklleed lraeipqtlt emyihflliq inmrkqkyee rdpekllpsn revivklaev
      541 afkqlmkgnv mfyeedlies gidvtdasvy sgicteifkq esvihqrkvy sfihlsvqef
      601 laafylfycn ltknmeplhe fslyrsdnvs lydlltsavd kalkskngrl dlflrfllgv
      661 slesnqrllq dllthtenss etisrttedi khkiksshyl sadqsinlfl cllevkdqtl
      721 freiqefvks nkhseeklsp aqcstisymi qmseepldel dlekyktsae grsrlipavi
      781 ncrkal
//
LOCUS       XP_026128623             753 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109188 [Carassius auratus].
ACCESSION   XP_026128623
VERSION     XP_026128623.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272838.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..753
                     /product="uncharacterized protein LOC113109188"
                     /calculated_mol_wt=85673
     Region          2..164
                     /region_name="Peptidase_A17"
                     /note="Pao retrotransposon peptidase; pfam05380"
                     /db_xref="CDD:461634"
     Region          384..434
                     /region_name="Integrase_H2C2"
                     /note="Integrase zinc binding domain; pfam17921"
                     /db_xref="CDD:465569"
     Region          655..748
                     /region_name="DUF5641"
                     /note="Family of unknown function (DUF5641); pfam18701"
                     /db_xref="CDD:465838"
     CDS             1..753
                     /gene="LOC113109188"
                     /coded_by="XM_026272838.1:40..2301"
                     /db_xref="GeneID:113109188"
ORIGIN      
        1 mrhiysilss qydplgfitp fttrakiivq rlwdkkrewd dpdlptdlkn awltwedelp
       61 qlscvtlprc yttkvdplts srtvhtfcda seraygavay lrtedskgqi evsflaarsr
      121 vapkkqqtip rlelcaaltg aqlaavlkre ltldissfry wtdsttvlnw lqsdschfkv
      181 fvgtrvaeiq eltdshlwsy vpsqdnpadd itrglslaql aeptrwkngp eflqkplssw
      241 pkmpnlepad tskelrkpvs fhliaqgdqh sviasqfdnf qelvnatars lhgaasstdt
      301 vtadtykkae lriiqqsqme sfpdeyaqlq agkaissnsr lktlaaefds dtqlirvggr
      361 lrrchllspd ilhqivldpv hpvtklliqq ydaqlhhpgt ervfaeirrr fwilrgrqav
      421 rsiqhhctec qrwrgkpnip kmadlppssl rlfqpafyst gmdcfgpfii kigrrnekrw
      481 giiykclttr avyidllsqa dtdsflmslr rfiarrgkph evcsdqgtnf kggdrelkea
      541 fnnihpqlqr elakqqidfh ynppnsphfg gswereirsl kaalyttigv qtvteevlrt
      601 vlveiegiln skplgyvssd vadpdpitpn sllmgrrdsa lpqviypase llsrkrwrhs
      661 qiladqfwss ymrnylpglq srqkwqqekd nltvgtvvmv adpqfpralr pvgtvksvqv
      721 gadnkvraae iqikdrtyir pvvrliklps lpe
//
LOCUS       XP_026128624             737 aa            linear   VRT 18-JUN-2025
DEFINITION  NLR family CARD domain-containing protein 3-like [Carassius
            auratus].
ACCESSION   XP_026128624
VERSION     XP_026128624.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272839.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..737
                     /product="NLR family CARD domain-containing protein
                     3-like"
                     /calculated_mol_wt=84236
     Region          82..>579
                     /region_name="NACHT"
                     /note="Predicted NTPase, NACHT family domain [Signal
                     transduction mechanisms]; COG5635"
                     /db_xref="CDD:444362"
     Region          139..210
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          233..399
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          543..675
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..737
                     /gene="LOC113109189"
                     /coded_by="XM_026272839.1:190..2403"
                     /db_xref="GeneID:113109189"
ORIGIN      
        1 mgnkqtstdq efspgfssvd qkrseaessc vsvrsdtsmd ppgqfksgdt ktdlricsqr
       61 ssspdhscvs lksdrsmpgn ppalsdeavt sdpsradger sisggvssvf clnntsvtas
      121 lnkhdqavnd elqrvkeqhk tsmknkyerl ceglklqene sllnsiytql yiiegeregv
      181 neehevlqme ktartqhsqd apiycndifk asaeagseek eqiktkkmki ktvltkgiag
      241 igktvsvqkf ildwaegkan qdvdfmfvlp frelnlirdh qyslhrllld fhpelqdlds
      301 qiyeeckvvf ifdgldesri tlmfsdaqkv cdvtetssva vlmsklmkge llpsaliwit
      361 srpaaanqip seyihrltei qgftepqkee yfrkrisdeh qasriishir rarslhimch
      421 ipvfcwisst vlqklleedl raeipqtlte myihflliqi nmrkqkyeer dpekllpsdr
      481 evivklaeva fkqlmkgnvm fyeedliess idvtdasvys gicteifkqe svihqrkvys
      541 fihlsvqefl aafyllycyl tknkktlref rlnrsdkdsl ydlltsavdk alksengrld
      601 lflrfllgvs lesnqrllqd llthtensse tisrttryik hkikydpenh plsadqsinl
      661 flcllevkdq tlfreiqefv ksdkhseels aahcstisym iqmseeplde lnpmkyktsa
      721 egrrrlipav incrkav
//
LOCUS       XP_026128625             625 aa            linear   VRT 18-JUN-2025
DEFINITION  plastin-2 [Carassius auratus].
ACCESSION   XP_026128625
VERSION     XP_026128625.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272840.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..625
                     /product="plastin-2"
                     /calculated_mol_wt=69815
     Region          14..80
                     /region_name="EFh"
                     /note="EF-hand, calcium binding motif; A diverse
                     superfamily of calcium sensors and calcium signal
                     modulators; most examples in this alignment model have 2
                     active canonical EF hands. Ca2+ binding induces a
                     conformational change in the EF-hand motif, leading to...;
                     cd00051"
                     /db_xref="CDD:238008"
     Site            order(23,25,27,34,63,65,67,74)
                     /site_type="other"
                     /note="Ca2+ binding site [ion binding]"
                     /db_xref="CDD:238008"
     Region          99..241
                     /region_name="CH_PLS_rpt1"
                     /note="first calponin homology (CH) domain found in the
                     plastin family; cd21292"
                     /db_xref="CDD:409141"
     Site            order(121,125,188,190..191,194..195,197,206..214,219,
                     221..222,224..225,228..229,232)
                     /site_type="other"
                     /note="putative actin binding site [polypeptide binding]"
                     /db_xref="CDD:409141"
     Region          250..374
                     /region_name="CH_PLS2_rpt2"
                     /note="second calponin homology (CH) domain found in
                     plastin-2; cd21327"
                     /db_xref="CDD:409176"
     Site            order(265,269,328,330..331,334..335,337,345..353,358,
                     360..361,363..364,367..368,371)
                     /site_type="other"
                     /note="putative actin binding site [polypeptide binding]"
                     /db_xref="CDD:409176"
     Region          373..506
                     /region_name="CH_SF"
                     /note="calponin homology (CH) domain superfamily; cl00030"
                     /db_xref="CDD:469584"
     Site            order(399,454,456..457,460..461,463,477..481,486,488..489,
                     491..492,495..496,499)
                     /site_type="other"
                     /note="actin binding site [polypeptide binding]"
                     /db_xref="CDD:409180"
     Region          510..623
                     /region_name="CH_PLS2_rpt4"
                     /note="fourth calponin homology (CH) domain found in
                     plastin-2; cd21333"
                     /db_xref="CDD:409182"
     Site            order(516,520,576,578..579,582..583,585,593..601,606,
                     608..609,611..612,615..616,619)
                     /site_type="other"
                     /note="putative actin binding site [polypeptide binding]"
                     /db_xref="CDD:409182"
     CDS             1..625
                     /gene="LOC113109190"
                     /coded_by="XM_026272840.1:150..2027"
                     /db_xref="GeneID:113109190"
ORIGIN      
        1 magtshipae emeelreafs kvdvdgnghi ctneltdlfk aanlplpgyr vreivqelsr
       61 tmdlnqdgki tfdefakvvh dlkssevakt frkainkkeg icsvagtseq sgtqhsysee
      121 ekvafvnwvn kalekdpdcq hvlpmdpssd dlftavgdgi vlckminlsv pdtidertin
      181 kkkltpftiq enlnlalnsa saigchvvni gaedlkegrq hlvlgllwqv ikiglfadie
      241 isrnealial lrdgetledl vklspeelll rwanyhleea gcskinnfss dikdskayyn
      301 ilnqvapkgd eegippipid msgirekddl kraecmleqa drlgcrqfvt atdvvrgnpk
      361 lnlayvanlf nkypalkkpe nqdidwssie getreertfr nwmnslgvnp rvnhlyvdls
      421 dalvifqlye kikvpvdwdk vnkppytklg snmkklencn yavelgkkea kfslvgiagq
      481 dlhegnrtlt lallwqlmrr ytlniledlg dgqkvnddti vtwvndaltq agkgtisgfk
      541 dgsistsmpv ldlidaiqpg sirydllkte dltdeeklnn akyaismark igarvyalpe
      601 dlvevkpkmv mtvfaclmar gmrhi
//
LOCUS       XP_026128626             589 aa            linear   VRT 18-JUN-2025
DEFINITION  arylsulfatase D [Carassius auratus].
ACCESSION   XP_026128626
VERSION     XP_026128626.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272841.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..589
                     /product="arylsulfatase D"
                     /calculated_mol_wt=65780
     Region          38..558
                     /region_name="ALP_like"
                     /note="alkaline phosphatases and sulfatases; cl23718"
                     /db_xref="CDD:474031"
     Site            order(47,87,302,354..355)
                     /site_type="active"
                     /db_xref="CDD:293732"
     Site            order(47,87,302,355)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:293732"
     CDS             1..589
                     /gene="arsh"
                     /coded_by="XM_026272841.1:10..1779"
                     /db_xref="GeneID:113109191"
ORIGIN      
        1 mtaesdpapl fcrlfsavlv llwsgspvsr agseqdsrpn fvlmmlddlg igdigcygnh
       61 tirtpnidrl aaegvkltqh lsaaplctps rsafmtgrya lrsglgstgr vqvilflags
      121 gglppnettf akllqkqgyt tgivgkwhlg vncesrndhc hhpnnhgfdf fyglpftlfs
      181 dckpgagkgv lvdmqetlwl mfmllalafl tllpvrvagl lripgtlllf laalsllsft
      241 vwfvpfellr twnciimrng evleqpmkle tlnarlmrea qgfverhrdk pfllflslah
      301 vhtplfvsed fagkskhgly gdnveeadwm igrmmdtiqr lnlsektlmy ftsdhgghie
      361 egprggwngi yrggkamggw eggirvpgif rwpgrlipgr evseptslmd vfptvvklag
      421 galpedrild ghdlmpllen rssrsehefm fhycgmylna vrwhptnsds ifkvhfftpn
      481 fspagavgcy diniclchge fvtyhspplv fdlsrdpses lpltpdtepl fsevlerver
      541 avtehrrslr pvekqlswek vlwkpwlqpc cgtfpfcscq eisstqhth
//
LOCUS       XP_026128627             553 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109192 [Carassius auratus].
ACCESSION   XP_026128627
VERSION     XP_026128627.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272842.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..553
                     /product="uncharacterized protein LOC113109192"
                     /calculated_mol_wt=61812
     Region          <155..>350
                     /region_name="Herpes_BLLF1"
                     /note="Herpes virus major outer envelope glycoprotein
                     (BLLF1); pfam05109"
                     /db_xref="CDD:282904"
     CDS             1..553
                     /gene="LOC113109192"
                     /coded_by="XM_026272842.1:241..1902"
                     /db_xref="GeneID:113109192"
ORIGIN      
        1 mslkeqatsl pqtetsdrps rhrrtprhle eyhvdyghhr palfssptee vqveqrgaaa
       61 avglasqsrt vsrqgehpdt ssmdllsmss lrkmlktisd kekdeaadma alhsnlqqye
      121 krqrrrkelm ehitsflree edeeddqsek hiappvrsps vtsprlppss httpsqspdi
      181 elptqgcvsd mqknaskspv eaedfnsgfv picpvssipl yspvssgtip tvshqqqpat
      241 raetvpplft kqspiydagk afqpqvqppl mapkpvyqhl navygyltgs psqqqftalp
      301 tasfatphyt lmtpaasvsq tqprvpvmtl nppafdtpsl qpfnkalnpt eyfvpqrplh
      361 aapqpkipdf vndnerefan lklaldnlle phaeldekyk yhillehlkl peaqmfgqsc
      421 rhhlypysaa mqalqlqygq phqlaqseia ailtapevkp ndahsfqsfa lrvhllvsml
      481 lslegtrgme lnccshvdrl lsklpkylrd gfieflqlrg klnspsinpy nlqdfagwlq
      541 vkaqqqrlss rlv
//
LOCUS       XP_026128629             531 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109193 [Carassius auratus].
ACCESSION   XP_026128629
VERSION     XP_026128629.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272844.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..531
                     /product="uncharacterized protein LOC113109193"
                     /calculated_mol_wt=60015
     CDS             1..531
                     /gene="LOC113109193"
                     /coded_by="XM_026272844.1:472..2067"
                     /db_xref="GeneID:113109193"
ORIGIN      
        1 msgmkevlkd avllvlpsls pdvtnqlvek lmdqgvegld dlvyvkeddi lefirpiqcr
       61 kllsswknqe hqnctvvlpp aevlpsvppe tnttlgspps sssrptsssl asasvthswt
      121 enfqvpwnlm pdgiksaven gqrpspsdrr qmiriladem rkhdknptrs qcltvsrkiv
      181 sqypksfadm lgdkqvgggy esvfsqlkvr iehlnrtntl shhriqrsdt gttrkrsstd
      241 sygctrwqpd lppretydsl evkrqkmeem hlhegisgae rgdvcklmee tywlqrhmin
      301 atpsptiadi ktkwpylftq rhiyghfeql tdkkvlrcle lsiqecgqii ieffkskpts
      361 ddirsilsrg endvdamviq lllahfkekl dgvflqadef atpsdvqhsl nlpesprlif
      421 lgqslsnqcw mlslegqivc egaqpnfitg laalfasfyn fnlqyqeeaa ctlefvqrrf
      481 vdinpergsk akkgkmtskk tgqvvqkkna tvsppvssll rkladfewnf v
//
LOCUS       XP_026128630             512 aa            linear   VRT 18-JUN-2025
DEFINITION  A-kinase anchor protein 17A [Carassius auratus].
ACCESSION   XP_026128630
VERSION     XP_026128630.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272845.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..512
                     /product="A-kinase anchor protein 17A"
                     /calculated_mol_wt=60710
     Region          141..263
                     /region_name="RRM_AKAP17A"
                     /note="RNA recognition motif (RRM) found in A-kinase
                     anchor protein 17A (AKAP-17A) and similar proteins;
                     cd12264"
                     /db_xref="CDD:409708"
     CDS             1..512
                     /gene="akap17a"
                     /coded_by="XM_026272845.1:173..1711"
                     /db_xref="GeneID:113109194"
ORIGIN      
        1 mtsvvsdtae avdlcpelsl ylkpisritv svalphlktp gksisnwevm erlkgmvhpe
       61 tfsslrisks smdflrfege venrsavkrs laklegksik lsgftdvlki ravehktdfp
      121 trhdwdsffr dakdmnetvp gerpdtihle glpckwfsak dgapdrpsea vlrtvfqrfg
      181 kirnvdipml dpyreemtgk nfntfsfggh lnfegfvqyq dhtgfvramd slrgmklmfk
      241 gddgkavacs ikvtfdttkh lsesslkkrq qervklqele kqreeqkrre keeeerrred
      301 errqreqeee ekerrreekv rkreqklkek eekktqkklk kqqeeeqkkl qlkisteerk
      361 lllaqrnles irliaellsr akrlkeqqqq errrleerrq lqeeelrrve aekertlelq
      421 rkerqlrdkl lgnllkksts adavhldlqi catqteslrk epreatkqek rkesdadggr
      481 rehrrsrrrr srthsrsrsr srrrshhrsr rh
//
LOCUS       XP_026128631             501 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger BED domain-containing protein 4-like [Carassius
            auratus].
ACCESSION   XP_026128631
VERSION     XP_026128631.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272846.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..501
                     /product="zinc finger BED domain-containing protein
                     4-like"
                     /calculated_mol_wt=55912
     Region          419..495
                     /region_name="Dimer_Tnp_hAT"
                     /note="hAT family C-terminal dimerization region;
                     pfam05699"
                     /db_xref="CDD:399013"
     CDS             1..501
                     /gene="LOC113109195"
                     /coded_by="XM_026272846.1:552..2057"
                     /db_xref="GeneID:113109195"
ORIGIN      
        1 meficldhqp lsvvedegfq rlmsyldsry tlpgrkyftd vclpqlyqtv ftyvdslmkd
       61 nitsigftsd iwsasvcpms mlsltaqfin qnfelqkvvl hsqkfsgsht aealvaafsd
      121 mfqawgipke kvhvilrdnt knmekamrda hlpslpcmah slqlavtegv msqrsiadii
      181 asgrlivghf khsplaysrl qsiqkqlgqp ikrlqqdvpt rwnstvymlq slleqkralc
      241 ayvadydlps mftssqwklv enmislltpf eeltqqisss tasaadvips iraltrllek
      301 taetdhgvkt skatlleavq krfrdiecer lysiatildp rykdryfsda vkpqirglls
      361 nvlatgleqq dgeaslaasg sgppekvprt gslhamyael lggdqecgss ensssaslql
      421 nfylsepvia qsgqplvywq nnksrfpaar tylcalctsv dserlfstag niidekrnkl
      481 saknaemlif ikknlplmlk k
//
LOCUS       XP_026128632             460 aa            linear   VRT 18-JUN-2025
DEFINITION  UBX domain-containing protein 4-like [Carassius auratus].
ACCESSION   XP_026128632
VERSION     XP_026128632.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272847.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..460
                     /product="UBX domain-containing protein 4-like"
                     /calculated_mol_wt=51522
     Region          <157..>283
                     /region_name="Smc"
                     /note="Chromosome segregation ATPase Smc [Cell cycle
                     control, cell division, chromosome partitioning]; COG1196"
                     /db_xref="CDD:440809"
     Region          276..352
                     /region_name="UBX_UBXN4"
                     /note="Ubiquitin regulatory domain X (UBX) found in UBX
                     domain protein 4 (UBXN4) and similar proteins; cd16117"
                     /db_xref="CDD:340534"
     Site            order(278,280,282..283,286..287,289,322..323,325,344..347,
                     349,351)
                     /site_type="other"
                     /note="putative UBX-p97 interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:340534"
     CDS             1..460
                     /gene="LOC113109196"
                     /coded_by="XM_026272847.1:99..1481"
                     /db_xref="GeneID:113109196"
ORIGIN      
        1 mrwfegsipa aiaaakerrc vfvvvitgsd dqstqlmssw eadsvceaaq dccvairvda
       61 esetcvqfsq iypvvcipss ffigengvpl eviagsvted elqrrisrvt qmhtqqtsae
      121 ranqtpvsep qakeslsepm eedgaaghvt pgedepldtk veritkklee rreqkkkaee
      181 enelkkemer rkmgkevldf krqqeeektk hlleernrek aeeraarerv kqqialdrad
      241 raarlaqtql eadtsrtaal qtratqqevq reksaftriq frlpdgssvt nqfpsesrll
      301 earqfaarea gsrygqfsla tmfprrefta edlertllel dltpsacivl lpqsrsavvr
      361 ssasgsvwaa lgsllyplls vwrfisgflf ssappapaaa aahnthgsga aaqpqrdavr
      421 krvlekkped fkkdgkiyrl rtqededdnn twngnstqqm
//
LOCUS       XP_026128633             452 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109197 isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128633
VERSION     XP_026128633.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272848.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..452
                     /product="uncharacterized protein LOC113109197 isoform X1"
                     /calculated_mol_wt=51431
     Region          4..211
                     /region_name="KDZ"
                     /note="Kyakuja-Dileera-Zisupton transposase; pfam18758"
                     /db_xref="CDD:465857"
     CDS             1..452
                     /gene="LOC113109197"
                     /coded_by="XM_026272848.1:2380..3738"
                     /db_xref="GeneID:113109197"
ORIGIN      
        1 mlavsvdgnr khhrfknaar seekalfdgi fiakddever fvdyihsttn hvsgrgvcgg
       61 kwsaaretsq kssskideeg lelavcrhgv fltalnmfrg eiyayplylq nklantpisf
      121 famdvtckyw pylnkvtksc pelqhllsmk pflsvfhaka hdfkcevkws gayqqgaglt
      181 lgeeveqcna flsriavttk hmskagrtdm ltlmamrlnq qkfnnlatsl acryqkatkr
      241 lesmriqlav tqvevegwvt dikewaaatt sqknadldav inrievlvas ikrrsqrlyk
      301 dtdgskgrar irrkireeka ilssvvekyn smvpdteria fdiilsdetv wpwqlshgda
      361 vdlktkrkaf dvvmairrle eekkivlsem akhwkslstr adtlkemscq lssealksel
      421 wdlneegikg flsltlrkkq evtrmmkhar dc
//
LOCUS       XP_026128634             447 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109197 isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128634
VERSION     XP_026128634.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272849.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..447
                     /product="uncharacterized protein LOC113109197 isoform X2"
                     /calculated_mol_wt=50902
     Region          4..211
                     /region_name="KDZ"
                     /note="Kyakuja-Dileera-Zisupton transposase; pfam18758"
                     /db_xref="CDD:465857"
     CDS             1..447
                     /gene="LOC113109197"
                     /coded_by="XM_026272849.1:2378..3721"
                     /db_xref="GeneID:113109197"
ORIGIN      
        1 mlavsvdgnr khhrfknaar seekalfdgi fiakddever fvdyihsttn hvsgrgvcgg
       61 kwsaaretsq kssskideeg lelavcrhgv fltalnmfrg eiyayplylq nklantpisf
      121 famdvtckyw pylnkvtksc pelqhllsmk pflsvfhaka hdfkcevkws gayqqgaglt
      181 lgeeveqcna flsriavttk hmskagrtdm ltlmamrlnq qkfnnlatsl acryqkatkr
      241 lesmriqlav tqvevegwvt dikewaaatt sqknadldav inrievlvas ikrrsqrlyk
      301 dtdgskgrar irrkireeka ilssvvekyn smvpdteria fdiilsdetv wpwqlshgda
      361 vdlktkrkaf dvvmairrle eekkivlsem akhwkslstr adtlkemscq lsselwdlne
      421 egikgflslt lrkkqevtrm mkhardc
//
LOCUS       XP_026128635             445 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109198 isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128635
VERSION     XP_026128635.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272850.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..445
                     /product="uncharacterized protein LOC113109198 isoform X1"
                     /calculated_mol_wt=46560
     Region          <366..429
                     /region_name="CD99L2"
                     /note="CD99 antigen like protein 2; pfam12301"
                     /db_xref="CDD:463526"
     CDS             1..445
                     /gene="LOC113109198"
                     /coded_by="XM_026272850.1:178..1515"
                     /db_xref="GeneID:113109198"
ORIGIN      
        1 mksslwvfil gslivtgvkm qdspaddlaa eesavpdeae daekpaedpa peetpeetpg
       61 etpeetpget peetpeetpg etpeetpeet pgetpeetpg etpeetpget peetpgetpe
      121 etpeetpget peetpgetpe etpgetpeet peetpeetpe etpgetpeet pgetpeetpg
      181 etpeetpget peetpgetpe etpgetpget peetpgetpg etpeetpget pgetpeetpg
      241 etpgetpeet pgetpgetpe etpgetpekt peeaeeeaaa ptdeadkate tetdpavgdp
      301 evteeeispr kapgeaeept qedtegawtt vpeepvhsgd aakevkaqae npvenavraa
      361 drhvagqgkg rsagavsesn dsgsgtvagv vcgiavaavg aiigyftyqk kklcfrvqrg
      421 dpesareeng tqndpqvlst llnss
//
LOCUS       XP_026128636             444 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109198 isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128636
VERSION     XP_026128636.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272851.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..444
                     /product="uncharacterized protein LOC113109198 isoform X2"
                     /calculated_mol_wt=46489
     Region          <365..428
                     /region_name="CD99L2"
                     /note="CD99 antigen like protein 2; pfam12301"
                     /db_xref="CDD:463526"
     CDS             1..444
                     /gene="LOC113109198"
                     /coded_by="XM_026272851.1:177..1511"
                     /db_xref="GeneID:113109198"
ORIGIN      
        1 mksslwvfil gslivtgvkm qdspaddlaa eesavpdeed aekpaedpap eetpeetpge
       61 tpeetpgetp eetpeetpge tpeetpeetp getpeetpge tpeetpgetp eetpgetpee
      121 tpeetpgetp eetpgetpee tpgetpeetp eetpeetpee tpgetpeetp getpeetpge
      181 tpeetpgetp eetpgetpee tpgetpgetp eetpgetpge tpeetpgetp getpeetpge
      241 tpgetpeetp getpgetpee tpgetpektp eeaeeeaaap tdeadkatet etdpavgdpe
      301 vteeeisprk apgeaeeptq edtegawttv peepvhsgda akevkaqaen pvenavraad
      361 rhvagqgkgr sagavsesnd sgsgtvagvv cgiavaavga iigyftyqkk klcfrvqrgd
      421 pesareengt qndpqvlstl lnss
//
LOCUS       XP_026128638             444 aa            linear   VRT 18-JUN-2025
DEFINITION  CCR4-NOT transcription complex subunit 11 [Carassius auratus].
ACCESSION   XP_026128638
VERSION     XP_026128638.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272853.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..444
                     /product="CCR4-NOT transcription complex subunit 11"
                     /calculated_mol_wt=49407
     Region          305..428
                     /region_name="CNOT11"
                     /note="CCR4-NOT transcription complex subunit 11;
                     pfam10155"
                     /db_xref="CDD:401964"
     CDS             1..444
                     /gene="cnot11"
                     /coded_by="XM_026272853.1:249..1583"
                     /db_xref="GeneID:113109200"
ORIGIN      
        1 mtlapkelsn llgimsdeac snsfeqlsta fhhcfgkadh fgvgsvlvml lqqpdllpsa
       61 pqrltalyll wemyrtepla anpfaavfah llnpssaade qdtlsgflpp itlpekyfls
      121 qlmlapprdl fkktprqvss mdmsstpqti disglqlala erqselptqs kasfpsllsd
      181 pdpdssnsgf dssvanqite clvtgprpal eshfrpefir pappllvced elswlnpcep
      241 dhriqwdrsm cvrsgtglei krimvkafks plsaaqqtql lgelekdpkl vyhigltpak
      301 lpdlvennpl vaiemllklm sssqiteyfs vlvnmdmslh smevvnrltt avdlppefih
      361 lyisncistc eqikdkymqn rlvrlvcvfl qslirnkiin vqdlfievqa fciefsrire
      421 aaglfrllkt ldngempaeg ktak
//
LOCUS       XP_026128639             444 aa            linear   VRT 18-JUN-2025
DEFINITION  CCR4-NOT transcription complex subunit 11 [Carassius auratus].
ACCESSION   XP_026128639
VERSION     XP_026128639.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272854.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..444
                     /product="CCR4-NOT transcription complex subunit 11"
                     /calculated_mol_wt=49407
     Region          305..428
                     /region_name="CNOT11"
                     /note="CCR4-NOT transcription complex subunit 11;
                     pfam10155"
                     /db_xref="CDD:401964"
     CDS             1..444
                     /gene="cnot11"
                     /coded_by="XM_026272854.1:231..1565"
                     /db_xref="GeneID:113109200"
ORIGIN      
        1 mtlapkelsn llgimsdeac snsfeqlsta fhhcfgkadh fgvgsvlvml lqqpdllpsa
       61 pqrltalyll wemyrtepla anpfaavfah llnpssaade qdtlsgflpp itlpekyfls
      121 qlmlapprdl fkktprqvss mdmsstpqti disglqlala erqselptqs kasfpsllsd
      181 pdpdssnsgf dssvanqite clvtgprpal eshfrpefir pappllvced elswlnpcep
      241 dhriqwdrsm cvrsgtglei krimvkafks plsaaqqtql lgelekdpkl vyhigltpak
      301 lpdlvennpl vaiemllklm sssqiteyfs vlvnmdmslh smevvnrltt avdlppefih
      361 lyisncistc eqikdkymqn rlvrlvcvfl qslirnkiin vqdlfievqa fciefsrire
      421 aaglfrllkt ldngempaeg ktak
//
LOCUS       XP_026128640             418 aa            linear   VRT 18-JUN-2025
DEFINITION  actin-related protein 3-like [Carassius auratus].
ACCESSION   XP_026128640
VERSION     XP_026128640.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272855.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..418
                     /product="actin-related protein 3-like"
                     /calculated_mol_wt=47202
     Region          7..410
                     /region_name="ASKHA_NBD_Arp3-like"
                     /note="nucleotide-binding domain (NBD) of actin-related
                     protein3 (Arp3) and similar proteins; cd10221"
                     /db_xref="CDD:466822"
     CDS             1..418
                     /gene="LOC113109201"
                     /coded_by="XM_026272855.1:113..1369"
                     /db_xref="GeneID:113109201"
ORIGIN      
        1 maarlpacvv dcgtgytklg yagntepqfi ipsciaikes akvgdqaqrr mmkgvddldf
       61 figdeaidkp nyatkwpirh givedwdlme rfmeqvifky lraepedhyf lltepplntp
      121 enreytaeim fesfnvpgly iavqavlala aswtsrqvge rtltgsvids gdgvthvipv
      181 aegyvigsci khipiagrdi tyftqqllre revgippeqs letakavker fsyvcpdlvk
      241 efskydtdgs kwikqytgin aiskkeftid vgyerflgpe iffhpefanp dftqpisevv
      301 deviqncpid vrrplyknvv lsggstmfrd fgrrlqrdlk rtvdarlkls eelsggklkp
      361 kpidvqvith hmqryavwfg gsmlastpef yqvchtkkdy eeigpsicrh npvfgvms
//
LOCUS       XP_026128641             390 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109202 [Carassius auratus].
ACCESSION   XP_026128641
VERSION     XP_026128641.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272856.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..390
                     /product="uncharacterized protein LOC113109202"
                     /calculated_mol_wt=44882
     CDS             1..390
                     /gene="LOC113109202"
                     /coded_by="XM_026272856.1:508..1680"
                     /db_xref="GeneID:113109202"
ORIGIN      
        1 mkgdvereyl spdlnllrmf rlykennpas takfwlyrdi fkqqnlsfgq prsdtcakcd
       61 alfsklvatt tdgerlkita kselhhrkae kaytqlqadt ewakanddch vicidmqgvv
      121 ytpnlthsnv yyqrqlanyn lciqemgtdk pptmclwheg iahrgsieva scllkwaets
      181 faplvqaker kliiysdrcc gqnnnwrvln lmallvsrgy fsqieqkfmv sghsflpcdr
      241 sfatldkrrk vstlhtpsdv aemirgarql hpfkviemkc adfrqlpdat lkhppgflit
      301 smmwlkvtat dpwcvhtkgs hslyegwkhw litkqrknqp ppaplfstty arayedplpi
      361 kkekhrdlmk mlaympaeaq afygtlecee
//
LOCUS       XP_026128642             390 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109202 [Carassius auratus].
ACCESSION   XP_026128642
VERSION     XP_026128642.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272857.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..390
                     /product="uncharacterized protein LOC113109202"
                     /calculated_mol_wt=44882
     CDS             1..390
                     /gene="LOC113109202"
                     /coded_by="XM_026272857.1:481..1653"
                     /db_xref="GeneID:113109202"
ORIGIN      
        1 mkgdvereyl spdlnllrmf rlykennpas takfwlyrdi fkqqnlsfgq prsdtcakcd
       61 alfsklvatt tdgerlkita kselhhrkae kaytqlqadt ewakanddch vicidmqgvv
      121 ytpnlthsnv yyqrqlanyn lciqemgtdk pptmclwheg iahrgsieva scllkwaets
      181 faplvqaker kliiysdrcc gqnnnwrvln lmallvsrgy fsqieqkfmv sghsflpcdr
      241 sfatldkrrk vstlhtpsdv aemirgarql hpfkviemkc adfrqlpdat lkhppgflit
      301 smmwlkvtat dpwcvhtkgs hslyegwkhw litkqrknqp ppaplfstty arayedplpi
      361 kkekhrdlmk mlaympaeaq afygtlecee
//
LOCUS       XP_026128643             375 aa            linear   VRT 18-JUN-2025
DEFINITION  N-myc-interactor-like [Carassius auratus].
ACCESSION   XP_026128643
VERSION     XP_026128643.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272858.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..375
                     /product="N-myc-interactor-like"
                     /calculated_mol_wt=42833
     Region          21..119
                     /region_name="APG6_N"
                     /note="Apg6 coiled-coil region; pfam17675"
                     /db_xref="CDD:465452"
     Region          167..254
                     /region_name="NID"
                     /note="Nmi/IFP 35 domain (NID); pfam07292"
                     /db_xref="CDD:462137"
     Region          267..352
                     /region_name="NID"
                     /note="Nmi/IFP 35 domain (NID); pfam07292"
                     /db_xref="CDD:462137"
     CDS             1..375
                     /gene="LOC113109203"
                     /coded_by="XM_026272858.1:144..1271"
                     /db_xref="GeneID:113109203"
ORIGIN      
        1 msdadenrvn gelradtsdp eaeikkykdl iesadtersr lllekaeaet ekrkaeaelq
       61 sfmddedkif dqfnkdlvea qeerksldrv qqdlkrelhd lqqklqlkrd etdslqrrfk
      121 ieasipvkav kfvreleree deeaddqvqc vftvtqrpsl llkggqalit fedekvaeqi
      181 lrlakcsvac dkakmdvkpy alsldpsvkf evhiqvskks irfcnapptl peermrdrle
      241 lsfsrvsrgg gevekleyhr dtcsgrvtfl stgvaenlvh rgkfcvdtgs dvvldvlply
      301 eyqlrkfqty sgtphrtvll ggiqalmdee dlqdhleihf qkpsnyggev ehikyvpdga
      361 qltaffsedg kedea
//
LOCUS       XP_026128644             343 aa            linear   VRT 18-JUN-2025
DEFINITION  acetylserotonin O-methyltransferase isoform X1 [Carassius auratus].
ACCESSION   XP_026128644
VERSION     XP_026128644.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272859.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..343
                     /product="acetylserotonin O-methyltransferase isoform X1"
                     /calculated_mol_wt=38577
     Region          11..98
                     /region_name="dimerization2"
                     /note="dimerization domain; pfam16864"
                     /db_xref="CDD:465287"
     Region          115..324
                     /region_name="Methyltransf_2"
                     /note="O-methyltransferase domain; pfam00891"
                     /db_xref="CDD:395719"
     CDS             1..343
                     /gene="asmt"
                     /coded_by="XM_026272859.1:102..1133"
                     /db_xref="GeneID:113109204"
ORIGIN      
        1 mageepyprk ilqymegflv skalfsacel gvferlqgsq wsasdlalsl gcsedgmerl
       61 lntcvslell tartdphgav vysntemssm fllkssprsl cqsieyssrt iylcwhylsd
      121 avregrnqye kafgvdsrdl feamyrsdee mvkfmhlmns vwnicgrdvi tafdlspfrc
      181 icdlggcsga lakqcvsafp qstvtifdlp kvvrtsqqhf vcnqdericf cegdffkdel
      241 pqadlyilar ilhdwtdqrs velltkiyqs crpggavllv eallyedntg pltaqlysln
      301 mlvqtegrer kasdysrlls aagfthiqih ntgkiydail ahk
//
LOCUS       XP_026128646             311 aa            linear   VRT 18-JUN-2025
DEFINITION  acetylserotonin O-methyltransferase isoform X2 [Carassius auratus].
ACCESSION   XP_026128646
VERSION     XP_026128646.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272861.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..311
                     /product="acetylserotonin O-methyltransferase isoform X2"
                     /calculated_mol_wt=34712
     Region          11..98
                     /region_name="dimerization2"
                     /note="dimerization domain; pfam16864"
                     /db_xref="CDD:465287"
     Region          115..289
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     CDS             1..311
                     /gene="asmt"
                     /coded_by="XM_026272861.1:104..1039"
                     /db_xref="GeneID:113109204"
ORIGIN      
        1 mageepyprk ilqymegflv skalfsacel gvferlqgsq wsasdlalsl gcsedgmerl
       61 lntcvslell tartdphgav vysntemssm fllkssprsl cqsieyssrt iylcwhylsd
      121 avregrnqye kafgvdsrdl feamyrsdee mvkfmhlmns vwnicgrdvi tafdlspfrc
      181 icdlggcsga lakqcvsafp qstvtifdlp kvvrtsqqhf vcnqdericf cegdffkdel
      241 pqadlyilar ilhdwtdqrs velltkiyqs crpggavllv eallyednsv cvcvcvcvcr
      301 wscaagggss v
//
LOCUS       XP_026128647             286 aa            linear   VRT 18-JUN-2025
DEFINITION  acetylserotonin O-methyltransferase isoform X3 [Carassius auratus].
ACCESSION   XP_026128647
VERSION     XP_026128647.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272862.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..286
                     /product="acetylserotonin O-methyltransferase isoform X3"
                     /calculated_mol_wt=32287
     Region          11..98
                     /region_name="dimerization2"
                     /note="dimerization domain; pfam16864"
                     /db_xref="CDD:465287"
     Region          115..>253
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     CDS             1..286
                     /gene="asmt"
                     /coded_by="XM_026272862.1:106..966"
                     /db_xref="GeneID:113109204"
ORIGIN      
        1 mageepyprk ilqymegflv skalfsacel gvferlqgsq wsasdlalsl gcsedgmerl
       61 lntcvslell tartdphgav vysntemssm fllkssprsl cqsieyssrt iylcwhylsd
      121 avregrnqye kafgvdsrdl feamyrsdee mvkfmhlmns vwnicgrdvi tafdlspfrc
      181 icdlggcsga lakqcvsafp qstvtifdlp kvvrtsqqhf vcnqdericf ceeaeflkdl
      241 haalklivhs chdpekskes hkaseqsfip ntnlydiski hskwim
//
LOCUS       XP_026128648             323 aa            linear   VRT 18-JUN-2025
DEFINITION  G2/M phase-specific E3 ubiquitin-protein ligase-like [Carassius
            auratus].
ACCESSION   XP_026128648
VERSION     XP_026128648.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272863.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..323
                     /product="G2/M phase-specific E3 ubiquitin-protein
                     ligase-like"
                     /calculated_mol_wt=36465
     Region          42..321
                     /region_name="HECTc"
                     /note="HECT domain; C-terminal catalytic domain of a
                     subclass of Ubiquitin-protein ligase (E3). It binds
                     specific ubiquitin-conjugating enzymes (E2), accepts
                     ubiquitin from E2, transfers ubiquitin to substrate lysine
                     side chains, and transfers additional...; cl27008"
                     /db_xref="CDD:474882"
     Site            order(146,149..150,155..156,159,166,168,172..173,175,186,
                     190)
                     /site_type="active"
                     /note="E2 interaction site [active]"
                     /db_xref="CDD:238033"
     CDS             1..323
                     /gene="LOC113109205"
                     /coded_by="XM_026272863.1:44..1015"
                     /db_xref="GeneID:113109205"
ORIGIN      
        1 mcmdlrtcae eqerqlinfy kqrnvewacp vkcqlegdaa vgdgvtrhff stileklkyg
       61 fslnlgntgv tclfegqpdh lvpsssqflt esdlflvagr mlghsflhgg pclaglsraf
      121 vhvllqgsqd tatlqledcp dvdiretinl lsgqsplned qsskvldlcl swdlpgptee
      181 nrrwlyerll shavlgrrvr qikqlkrglk dtcvwprlte rkdvvffpke sedsctpeml
      241 lshiscpres ddeddeeysa dikeritgyl kqfietassk dltnllkfwv gweqmeanma
      301 veivksdlpk ssscfcvlrl pgh
//
LOCUS       XP_026128649             322 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109206 [Carassius auratus].
ACCESSION   XP_026128649
VERSION     XP_026128649.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272864.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..322
                     /product="uncharacterized protein LOC113109206"
                     /calculated_mol_wt=36221
     Region          219..312
                     /region_name="DUF5641"
                     /note="Family of unknown function (DUF5641); pfam18701"
                     /db_xref="CDD:465838"
     CDS             1..322
                     /gene="LOC113109206"
                     /coded_by="XM_026272864.1:102..1070"
                     /db_xref="GeneID:113109206"
ORIGIN      
        1 messakgptd grfatrtpli alstfplncf gpylvkigrr nekrwglifk clttkavhie
       61 llnsmdvdaf llalrrfiar rgkpheirsd cgtnfrgadr elreafsime pelkvqlsdy
      121 qisfmfnpps aphfggiwer evrsiknalq valgtqavte dvlstvlvev egilnskplg
      181 yassdvadmd pitpnillmg rrdaslpqva yapgdmgrrr wrhcqnmvdq fwihftrnyl
      241 ptlqtrqkwh kasknlevds vvlivdpqlp raqwpigrvr ktlpssdgcv rtaeivvngk
      301 vytrpvarli elpalegntk di
//
LOCUS       XP_026128650             288 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109207 [Carassius auratus].
ACCESSION   XP_026128650
VERSION     XP_026128650.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272865.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..288
                     /product="uncharacterized protein LOC113109207"
                     /calculated_mol_wt=32195
     Region          163..>196
                     /region_name="Bbox1"
                     /note="B-box-type 1 zinc finger (Bbox1); cd19757"
                     /db_xref="CDD:380815"
     CDS             1..288
                     /gene="LOC113109207"
                     /coded_by="XM_026272865.1:1690..2556"
                     /db_xref="GeneID:113109207"
ORIGIN      
        1 msdhsnfeqv ldeldelveh selnyelqsl ddfinkmsge qeaapstshq pvrwlkrdsd
       61 gnvvydrprs srnqmashsy srkagahprm ldsycppdtv etfleernhs qgddlddqet
      121 apapprassd wstrksllse rwekeraclv ntmvaqqnvt tqicqqcgis paavrcrdcr
      181 pqpffcadcd vsihrnhvfh nrdatiagff qplppttcvv eralsqcvci vplempkkic
      241 scspgslsvn tgkvvavvtm ngknkmnlre hsrssgssvh itfwakcp
//
LOCUS       XP_026128651             285 aa            linear   VRT 18-JUN-2025
DEFINITION  G2/M phase-specific E3 ubiquitin-protein ligase-like [Carassius
            auratus].
ACCESSION   XP_026128651
VERSION     XP_026128651.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272866.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..285
                     /product="G2/M phase-specific E3 ubiquitin-protein
                     ligase-like"
                     /calculated_mol_wt=32179
     CDS             1..285
                     /gene="LOC113109208"
                     /coded_by="XM_026272866.1:36..893"
                     /db_xref="GeneID:113109208"
ORIGIN      
        1 mcmdlrtcae eqerqlinfy kqrnvewacp vkcqlegdaa vgdgvtrhff stileklkyg
       61 fslnlgntgv pclfegqpdl lvpsssqfli esdlflvagr mlghsflhgg pclaglsraf
      121 vhvllqgsqd tatlqledcp dvdiretinl lsgqsplned qssevldlcl swdlpgptee
      181 nrrwlyerll shavlgrrvr qikqlkrglk dtcvwprlte rkdvvffpke sedsctpeml
      241 lshiscpres ddeddeeysa dikeritgyl kqfietassk dlktf
//
LOCUS       XP_026128653             284 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109209 [Carassius auratus].
ACCESSION   XP_026128653
VERSION     XP_026128653.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272868.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..284
                     /product="uncharacterized protein LOC113109209"
                     /calculated_mol_wt=32890
     Region          <19..84
                     /region_name="KDZ"
                     /note="Kyakuja-Dileera-Zisupton transposase; pfam18758"
                     /db_xref="CDD:465857"
     CDS             1..284
                     /gene="LOC113109209"
                     /coded_by="XM_026272868.1:16..870"
                     /db_xref="GeneID:113109209"
ORIGIN      
        1 maeklpelqp ltmmkpflsv mhakahtgkc evrwggrsqd gagntvgeev eqvnsflsra
       61 alttkymtks gradmitvla mawnrrkees lhktlvkrfi kstqraemea anleslkqel
      121 nismddadqw vfdvkqwaas erqsthssqe elqreidemi ysirrkkhdl yrqndsnqtr
      181 qrkrrrlsel kktlqekilq yntlpgceek idtkaaccls ddfilpweaq gdvvslrlkr
      241 qlfdqvmlvr rmeeekiiiv kemtqhyqhl kknigqtghp psgn
//
LOCUS       XP_026128654             280 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109210 [Carassius auratus].
ACCESSION   XP_026128654
VERSION     XP_026128654.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272869.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..280
                     /product="uncharacterized protein LOC113109210"
                     /calculated_mol_wt=31385
     CDS             1..280
                     /gene="LOC113109210"
                     /coded_by="XM_026272869.1:16..858"
                     /db_xref="GeneID:113109210"
ORIGIN      
        1 mmsalitvfs lilgdaavgd gvtrhffsti leklkygfsl nlgntgvtcl fegqpdhlvp
       61 sssqfliesd lflvagrmlg hsflhggpcl aglsrafvhv llqgsqdtat lqledcpdvd
      121 iretinllsg qsplnedqss kvldlclswd lpgpteenrr wlyerllsha vlgrrvrqik
      181 qlkrglkdtc vwprlterkd vvffpkesed sctpemllsh iscpresdde ddeeysadik
      241 eritgylkqf ietasskdlk tfcssgsdgs rwrkiwlwkl
//
LOCUS       XP_026128655             217 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109211 isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128655
VERSION     XP_026128655.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272870.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..217
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..217
                     /product="uncharacterized protein LOC113109211 isoform X1"
                     /calculated_mol_wt=24721
     CDS             1..217
                     /gene="LOC113109211"
                     /coded_by="XM_026272870.1:152..805"
                     /db_xref="GeneID:113109211"
ORIGIN      
        1 mifllqlqys hlrgvdgfsr kimylgassn nlakttldff qeaaetfgfp lrvrgdqgve
       61 nvdvarlmft vretergsfi sgksvhnqrv erlwrdvwss vtnvyydvlh aleegghlni
      121 sdlthlfcch cvflprlqdd lnlfrntwdn hpirtegnms pnqlwvmgsv rnavpepdie
      181 lclwiltgfs tpqidwessg lmlmhipall clkpnvp
//
LOCUS       XP_026128656             214 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109211 isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128656
VERSION     XP_026128656.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272871.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..214
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..214
                     /product="uncharacterized protein LOC113109211 isoform X2"
                     /calculated_mol_wt=24277
     CDS             1..214
                     /gene="LOC113109211"
                     /coded_by="XM_026272871.1:695..1339"
                     /db_xref="GeneID:113109211"
ORIGIN      
        1 mlglqyshlr gvdgfsrkim ylgassnnla kttldffqea aetfgfplrv rgdqgvenvd
       61 varlmftvre tergsfisgk svhnqrverl wrdvwssvtn vyydvlhale egghlnisdl
      121 thlfcchcvf lprlqddlnl frntwdnhpi rtegnmspnq lwvmgsvrna vpepdielcl
      181 wiltgfstpq idwessglml mhipallclk pnvp
//
LOCUS       XP_026128657             214 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109211 isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128657
VERSION     XP_026128657.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272872.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..214
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..214
                     /product="uncharacterized protein LOC113109211 isoform X2"
                     /calculated_mol_wt=24277
     CDS             1..214
                     /gene="LOC113109211"
                     /coded_by="XM_026272872.1:362..1006"
                     /db_xref="GeneID:113109211"
ORIGIN      
        1 mlglqyshlr gvdgfsrkim ylgassnnla kttldffqea aetfgfplrv rgdqgvenvd
       61 varlmftvre tergsfisgk svhnqrverl wrdvwssvtn vyydvlhale egghlnisdl
      121 thlfcchcvf lprlqddlnl frntwdnhpi rtegnmspnq lwvmgsvrna vpepdielcl
      181 wiltgfstpq idwessglml mhipallclk pnvp
//
LOCUS       XP_026128658             192 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109211 isoform X3 [Carassius
            auratus].
ACCESSION   XP_026128658
VERSION     XP_026128658.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272873.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..192
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..192
                     /product="uncharacterized protein LOC113109211 isoform X3"
                     /calculated_mol_wt=22051
     CDS             1..192
                     /gene="LOC113109211"
                     /coded_by="XM_026272873.1:152..730"
                     /db_xref="GeneID:113109211"
ORIGIN      
        1 mifllqlqys hlrgvdgfsr kimylgassn nlakttldff qeaaetfgfp lrvrgdqgve
       61 nvdvarlmft vretergsfi sgksvhnqrv erlwrdvwss vtnvyydvlh aleegghlni
      121 sdlthlfcch cvflprlqdd lnlfrntwdn hpirtegnms pnqlwvmgsv rnavpepdie
      181 lwiqhttdrl ge
//
LOCUS       XP_026128659             202 aa            linear   VRT 18-JUN-2025
DEFINITION  ribonuclease inhibitor-like [Carassius auratus].
ACCESSION   XP_026128659
VERSION     XP_026128659.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272874.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..202
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..202
                     /product="ribonuclease inhibitor-like"
                     /calculated_mol_wt=22256
     Region          <6..200
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          23..51
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          52..80
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          81..109
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          110..138
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          139..167
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          168..189
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     CDS             1..202
                     /gene="LOC113109212"
                     /coded_by="XM_026272874.1:397..1005"
                     /db_xref="GeneID:113109212"
ORIGIN      
        1 minirdsgvk rlcavledpr ckleklwlrd cgitdegcsa lasalrsnps hliklnlsen
       61 kirdsgvkrl cagledphck letlwlrdcg vtdegcsalt salksnsshl relslslnki
      121 rdlgvkslca gledphckle ilglmkcdvt degcsaldsa lrsnpshlre ldltgntlrq
      181 sevkllsdlk ddpryklerl ly
//
LOCUS       XP_026128661             147 aa            linear   VRT 18-JUN-2025
DEFINITION  histone-lysine N-methyltransferase set-1-like [Carassius auratus].
ACCESSION   XP_026128661
VERSION     XP_026128661.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272876.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..147
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..147
                     /product="histone-lysine N-methyltransferase set-1-like"
                     /calculated_mol_wt=17020
     Region          21..132
                     /region_name="SET"
                     /note="SET (Su(var)3-9, Enhancer-of-zeste, Trithorax)
                     domain superfamily; cl40432"
                     /db_xref="CDD:394802"
     Site            order(23..24,88..93,102..104,129..132)
                     /site_type="active"
                     /db_xref="CDD:380914"
     Site            order(23..24,89..93,131)
                     /site_type="other"
                     /note="SAM binding site [polypeptide binding]"
                     /db_xref="CDD:380914"
     CDS             1..147
                     /gene="LOC113109213"
                     /coded_by="XM_026272876.1:19..462"
                     /db_xref="GeneID:113109213"
ORIGIN      
        1 mhhvvmksdk tkfevnyina vkgrglfakg sfckgdfive yrgelinyae lerrrklyhp
       61 scavfmfefk wrgktwcida sredgsfgrl vnddhqhpnc kmkkidvngk ahlclfalkd
      121 ikegeeityd yggddcpwrt qvscrnn
//
LOCUS       XP_026128662             134 aa            linear   VRT 18-JUN-2025
DEFINITION  ribonuclease inhibitor-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128662
VERSION     XP_026128662.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272877.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..134
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..134
                     /product="ribonuclease inhibitor-like isoform X1"
                     /calculated_mol_wt=14777
     Region          <2..>114
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     CDS             1..134
                     /gene="LOC113109214"
                     /coded_by="XM_026272877.1:374..778"
                     /db_xref="GeneID:113109214"
ORIGIN      
        1 mrcdvtdegc salasalrsn pshlrelsls vnkirdlgvk rlcavledpr ckleklwlmk
       61 cdvtdegcsa lasalrsnps hlrelnliln nlrqsgvkll sdlkddpryk letlyyysqy
      121 ldvssvssgs adge
//
LOCUS       XP_026128663             117 aa            linear   VRT 18-JUN-2025
DEFINITION  ribonuclease inhibitor-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128663
VERSION     XP_026128663.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272878.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..117
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..117
                     /product="ribonuclease inhibitor-like isoform X2"
                     /calculated_mol_wt=13057
     Region          <2..>114
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     CDS             1..117
                     /gene="LOC113109214"
                     /coded_by="XM_026272878.1:439..792"
                     /db_xref="GeneID:113109214"
ORIGIN      
        1 mrcdvtdegc salasalrsn pshlrelsls vnkirdlgvk rlcavledpr ckleklwlmk
       61 cdvtdegcsa lasalrsnps hlrelnliln nlrqsgvkll sdlkddpryk letlyyl
//
LOCUS       XP_026128664             129 aa            linear   VRT 18-JUN-2025
DEFINITION  neuromedin-S isoform X1 [Carassius auratus].
ACCESSION   XP_026128664
VERSION     XP_026128664.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272879.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..129
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..129
                     /product="neuromedin-S isoform X1"
                     /calculated_mol_wt=14591
     CDS             1..129
                     /gene="LOC113109215"
                     /coded_by="XM_026272879.1:282..671"
                     /db_xref="GeneID:113109215"
ORIGIN      
        1 mrsgaclfcs svlfiiifcs svesypsslt dcddyggyvq gsallsslcg vqwrnqdqeq
       61 iqnvfkrflf hyskahntvg svereshsvh plmrlspkls lrrkkqqmkk vcgssrrrlr
      121 dvlcsylgf
//
LOCUS       XP_026128665             109 aa            linear   VRT 18-JUN-2025
DEFINITION  neuromedin-S isoform X2 [Carassius auratus].
ACCESSION   XP_026128665
VERSION     XP_026128665.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272880.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..109
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..109
                     /product="neuromedin-S isoform X2"
                     /calculated_mol_wt=12346
     CDS             1..109
                     /gene="LOC113109215"
                     /coded_by="XM_026272880.1:295..624"
                     /db_xref="GeneID:113109215"
ORIGIN      
        1 mrsgaclfcs svlfiiifcs svesypsslt dcddyggyvq gsallsslcg vqwrnqdqeq
       61 iqnvfkrflf hyskahntvg svereshsvh plmrlspkls lrrkkqqrr
//
LOCUS       XP_026128666             123 aa            linear   VRT 18-JUN-2025
DEFINITION  60S ribosomal protein L31 [Carassius auratus].
ACCESSION   XP_026128666
VERSION     XP_026128666.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272881.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..123
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..123
                     /product="60S ribosomal protein L31"
                     /calculated_mol_wt=14195
     Region          17..98
                     /region_name="Ribosomal_L31e"
                     /note="Ribosomal protein L31e; pfam01198"
                     /db_xref="CDD:460108"
     CDS             1..123
                     /gene="LOC113109216"
                     /coded_by="XM_026272881.1:64..435"
                     /db_xref="GeneID:113109216"
ORIGIN      
        1 mapkkgekkk grsainevvt reytinihkr ihgvsfkrra pralkeirkf avkemgtpdv
       61 ridtrlnkav wakgvrnvpy rmrvrlsrkr nededspnkl ytlvtyvpvt thrglqtvnv
      121 den
//
LOCUS       XP_026128669              91 aa            linear   VRT 18-JUN-2025
DEFINITION  R3H domain-containing protein 1-like [Carassius auratus].
ACCESSION   XP_026128669
VERSION     XP_026128669.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272884.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..91
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..91
                     /product="R3H domain-containing protein 1-like"
                     /calculated_mol_wt=10283
     CDS             1..91
                     /gene="LOC113109217"
                     /coded_by="XM_026272884.1:343..618"
                     /db_xref="GeneID:113109217"
ORIGIN      
        1 mnilkrdnss tdrddsvmrm klkedrrser rsirepergs slmsdtaqgl dtfpldkrcm
       61 fsepvpcvwt avtdgfrvtp qqtgsqtdgr t
//
LOCUS       XP_026128670              91 aa            linear   VRT 18-JUN-2025
DEFINITION  R3H domain-containing protein 1-like [Carassius auratus].
ACCESSION   XP_026128670
VERSION     XP_026128670.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272885.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..91
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..91
                     /product="R3H domain-containing protein 1-like"
                     /calculated_mol_wt=10283
     CDS             1..91
                     /gene="LOC113109217"
                     /coded_by="XM_026272885.1:453..728"
                     /db_xref="GeneID:113109217"
ORIGIN      
        1 mnilkrdnss tdrddsvmrm klkedrrser rsirepergs slmsdtaqgl dtfpldkrcm
       61 fsepvpcvwt avtdgfrvtp qqtgsqtdgr t
//
LOCUS       XP_026128671              91 aa            linear   VRT 18-JUN-2025
DEFINITION  R3H domain-containing protein 1-like [Carassius auratus].
ACCESSION   XP_026128671
VERSION     XP_026128671.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272886.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..91
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..91
                     /product="R3H domain-containing protein 1-like"
                     /calculated_mol_wt=10283
     CDS             1..91
                     /gene="LOC113109217"
                     /coded_by="XM_026272886.1:263..538"
                     /db_xref="GeneID:113109217"
ORIGIN      
        1 mnilkrdnss tdrddsvmrm klkedrrser rsirepergs slmsdtaqgl dtfpldkrcm
       61 fsepvpcvwt avtdgfrvtp qqtgsqtdgr t
//
LOCUS       XP_026128673            2503 aa            linear   VRT 18-JUN-2025
DEFINITION  matrix-remodeling-associated protein 5 [Carassius auratus].
ACCESSION   XP_026128673
VERSION     XP_026128673.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272888.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2503
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2503
                     /product="matrix-remodeling-associated protein 5"
                     /calculated_mol_wt=277212
     Region          36..54
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          <44..>216
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          55..78
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          79..102
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          103..126
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          127..150
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          151..182
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          183..206
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          215..274
                     /region_name="LRRCT"
                     /note="Leucine rich repeat C-terminal domain; smart00082"
                     /db_xref="CDD:214507"
     Region          469..486
                     /region_name="FR1"
                     /note="FR1 [structural motif]"
                     /db_xref="CDD:409355"
     Region          475..477
                     /region_name="Ig strand A'"
                     /note="Ig strand A' [structural motif]"
                     /db_xref="CDD:409355"
     Region          476..542
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          479..487
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409355"
     Region          487..493
                     /region_name="CDR1"
                     /note="CDR1 [structural motif]"
                     /db_xref="CDD:409355"
     Site            order(493..494,496,542)
                     /site_type="other"
                     /note="antigen binding site [polypeptide binding]"
                     /db_xref="CDD:409355"
     Region          516..521
                     /region_name="Ig strand D"
                     /note="Ig strand D [structural motif]"
                     /db_xref="CDD:409355"
     Region          517..541
                     /region_name="FR3"
                     /note="FR3 [structural motif]"
                     /db_xref="CDD:409355"
     Region          535..542
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409355"
     Region          542..551
                     /region_name="CDR3"
                     /note="CDR3 [structural motif]"
                     /db_xref="CDD:409355"
     Region          577..643
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          580..584
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          593..597
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          619..623
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          633..638
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          1529..1609
                     /region_name="Ig_3"
                     /note="Immunoglobulin domain; pfam13927"
                     /db_xref="CDD:464046"
     Region          1633..1719
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          1645..1649
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          1658..1662
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          1685..1689
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          1699..1704
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          1712..1715
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          1735..1816
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          1742..1746
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          1755..1759
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          1782..1786
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          1796..1801
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          1809..1812
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          1832..1915
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          1841..1845
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          1854..1858
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          1881..1885
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          1895..1900
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          1927..2018
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          1938..1942
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          1951..1955
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          1984..1988
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          1998..2003
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          2033..2112
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          2041..2045
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          2054..2058
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          2078..2082
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          2092..2097
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          2127..2211
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          2138..2142
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          2151..2155
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          2177..2181
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          2191..2196
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          2204..2207
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          2217..2295
                     /region_name="Ig_3"
                     /note="Immunoglobulin domain; pfam13927"
                     /db_xref="CDD:464046"
     Region          2311..2390
                     /region_name="Ig_3"
                     /note="Immunoglobulin domain; pfam13927"
                     /db_xref="CDD:464046"
     Region          2407..2489
                     /region_name="Ig_3"
                     /note="Immunoglobulin domain; pfam13927"
                     /db_xref="CDD:464046"
     CDS             1..2503
                     /gene="mxra5b"
                     /coded_by="XM_026272888.1:200..7711"
                     /db_xref="GeneID:113109219"
ORIGIN      
        1 mgsscmglml vlmllvsfrv sggvcprlca csapaevhct fralltiptg isrqvqrinf
       61 gfntinhitd vsfaglqkle llmmhsnnvq kipeaafqdl vslqvlkmsy nklrvitght
      121 fsgltalvrl hldhnriefi hpdafsglts lrllhleanh lqklhpgtfs tfsllqrfpm
      181 stlkhlylse nllstlprnm lenmpqlenl flygnpwscd crmswlqdws arnpgvmkck
      241 kdrsfasgql cplcaspkhl krqdildlke ficsgpviss pgknasqeen msellpidri
      301 kppfgnislg lsdehgtkvd licqilepie ptkiswnytk sleiaanvtl ffdlecpvdr
      361 dnyesfwrll ayysevpvhl rreimlsrep elsyryrqdi erdtyfytgv ranvvarpsw
      421 lmqssvnikl nrpysssksm rlilnthltt ttdkepvrsw vmiehdnetq tsfssvvgga
      481 iemdchvqss gnaavhwmmp dgskikaafd stdkrvtvss sgklhiksve hrdsgvyyci
      541 aevagdtdvl pfrfsvtess tplpgeefgn altkfvgesa slpclttatp damvnwifpd
      601 gsvlnakans sralvfpngt lfipysqlnn ngyhkcvamn qhgvdvlvtk ltvmrrkgiq
      661 plrqypirpq saagvfskvk ayledveeas gdetrvpnrs finrrkgpna rtqgryfgni
      721 rhrrpfrkgm heqpnrtgst nqrtvntknn idpkkwaill akirektsqk nssvnivqhg
      781 aaemenvdhp gltddiesss gdsgpqeesn tfstphqadv fhkhaitphi kgqnnnvylt
      841 appelqtssd evpyisnpts ghhyvmkevn veerghvsti saendqvnsr svikpeseke
      901 nelsfsents vqsqiggfdf gqpdsnsfat tssphspsra kdqwssrrrf gvrqriklrl
      961 pfsklptrrp wststaagvh aptlkadpts paedtiiypt statgliysr tpskdtlihp
     1021 tstttahils typagslsvh ptipvtthiy sktlaeskse ylttspthpt vprvfpnain
     1081 eentiqlpde ktsskihkvn annflriqqm ptnsrtpsas pfmsttseld nkdisyfeee
     1141 edrsiasaek mdenlvptsv yptsrlgvem vplttaqqef tgmlstalpk ankeihptei
     1201 sftfdtdgld vfhlpeshfs nvlrendtle vssteeylvt smpqpldypl aqptesfked
     1261 ksihnqvsfp stpesiisvg rqteslatrs qsptlttqtn eiyllqpnsv skqdqrerfv
     1321 helneplirp ttlntlhtit lpattaiipn itqligktka sttlsiaatt agptsttsat
     1381 mmtttttttt paiksipsyl lpdnripfys rkpgtnyids rhrgrfpstn hrypyynsrn
     1441 psvdispnii rkpsgttspv dfnslnhdks tttpkiptat arsatssptt vssttqqnnq
     1501 iqideavnkq sgavmipqgp qmlpvlqmkp ritaaklstv tvnagtdvql scdsvgepkt
     1561 lltwtkvstg avissnnkiq rfevqsngtf vihnvqlqdr gqylcsarnp hgidkmmvtl
     1621 vvlahaprmm pphhkditvy lgnnafleck aqglpipnis wvlpdrsvvr avsnsqqkvm
     1681 lftngtlqvk ntnyldkgvy kciasnaagt dmlsvrlhia aspptiyeql wenytvsdgq
     1741 safmhcttkg tpgptlrwvt ftgaqlrpsq finsnlfvfp ngtlfirnpt eknsgnyecv
     1801 avnsvgvakr tvnlqvkrss ttarimstsa hsidvsyggq lslncsatgs pnpriiwktp
     1861 skklvdayys fdrrmkvfsn gtltitsvte kdegdylcva rnkmgddyvl lkvnvmmkaa
     1921 kidykslsdr evsyggelkv dcvasgfpnp eitwslpdgt mvnsipqsdd nrvrakryvm
     1981 fdngtlylnk vgmeeegdyt cyaenrigkd emkvhikvva dapiirnnvy sivkvpygen
     2041 ailncsakge ptpiitwtsp ahraivpvsd kyqiandstl hiqnvlnfds gnytclarnv
     2101 vgidkkvvhv evlvstpvin gfeslgivrk tvvkdqrvll dckaignpip rimwvfpnni
     2161 vlpapyygsr itvhrngtld ihtvrisdsv allciaqnkg geaklqfqle vtegdekprl
     2221 rnpptesvql sdgiinlncs vegkpppeit wilpngtsll rgtsifrfhh rfdgtlvird
     2281 psvseigryr cvgrnsigyv ertvtlesnr kpeitnkyss lvsiingenl hlnclsggqp
     2341 lpkltwtlpn gvvltrpqtt grysvlnngt lavhrasvyd rgmylcqttn ehgssslsvs
     2401 viviayppri tkgpspvtya spgvavqlnc vslatpkaev vwempdglql kvgiqpriyg
     2461 skylhpqgsl viqnpssrdn gvykctaknv vgsdsrstyv yvf
//
LOCUS       XP_026128674            2028 aa            linear   VRT 18-JUN-2025
DEFINITION  poly [ADP-ribose] polymerase 14-like [Carassius auratus].
ACCESSION   XP_026128674
VERSION     XP_026128674.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272889.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2028
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..2028
                     /product="poly [ADP-ribose] polymerase 14-like"
                     /calculated_mol_wt=225472
     Region          6..83
                     /region_name="RRM_SF"
                     /note="RNA recognition motif (RRM) superfamily; cl17169"
                     /db_xref="CDD:473069"
     Region          292..355
                     /region_name="RRM_SF"
                     /note="RNA recognition motif (RRM) superfamily; cl17169"
                     /db_xref="CDD:473069"
     Region          858..1021
                     /region_name="YmdB"
                     /note="O-acetyl-ADP-ribose deacetylase (regulator of RNase
                     III), contains Macro domain [Translation, ribosomal
                     structure and biogenesis]; COG2110"
                     /db_xref="CDD:441713"
     Region          1047..1210
                     /region_name="Macro_SF"
                     /note="macrodomain superfamily; cl00019"
                     /db_xref="CDD:469581"
     Site            order(1070,1082,1084,1126,1155..1162)
                     /site_type="other"
                     /note="putative ADP-ribose binding site [chemical
                     binding]"
                     /db_xref="CDD:394871"
     Region          1223..1390
                     /region_name="Macro_SF"
                     /note="macrodomain superfamily; cl00019"
                     /db_xref="CDD:469581"
     Site            order(1250,1262,1264,1306,1335..1342)
                     /site_type="other"
                     /note="putative ADP-ribose binding site [chemical
                     binding]"
                     /db_xref="CDD:394871"
     Region          1431..1595
                     /region_name="Macro_SF"
                     /note="macrodomain superfamily; cl00019"
                     /db_xref="CDD:469581"
     Site            order(1453,1465,1467,1510,1539..1546)
                     /site_type="other"
                     /note="putative ADP-ribose binding site [chemical
                     binding]"
                     /db_xref="CDD:394871"
     Region          1747..1807
                     /region_name="WWE"
                     /note="WWE domain; pfam02825"
                     /db_xref="CDD:460715"
     Region          <1833..>1904
                     /region_name="ADP_ribosyl"
                     /note="ADP_ribosylating enzymes catalyze the transfer of
                     ADP_ribose from NAD+ to substrates. Bacterial toxins are
                     cytoplasmic and catalyze the transfer of a single
                     ADP_ribose unit to eukaryotic elongation factor 2, halting
                     protein synthesis and killing the cell; cl00283"
                     /db_xref="CDD:444809"
     Region          1899..2020
                     /region_name="TCCD_inducible_PARP_like"
                     /note="Poly(ADP-ribose) polymerases catalyse the covalent
                     attachment of ADP-ribose units from NAD+ to itself and to
                     a limited number of other DNA binding proteins, which
                     decreases their affinity for DNA. Poly(ADP-ribose)
                     polymerase is a regulatory component...; cd01439"
                     /db_xref="CDD:238719"
     Site            order(1901..1905,1908,1912,1916..1918,1920,1933..1935,
                     1945,2003)
                     /site_type="other"
                     /note="nad+ binding pocket [chemical binding]"
                     /db_xref="CDD:238719"
     CDS             1..2028
                     /gene="LOC113109220"
                     /coded_by="XM_026272889.1:32..6118"
                     /db_xref="GeneID:113109220"
ORIGIN      
        1 meekslileg lpddfhrvkp kvelyfrnkr rsggetlqir ehpddkrkal lvyirdedlk
       61 kvldkkihkv dikphgsvev tvklpeetqi kikpqvlpkp rpetlalrss paaarqvspv
      121 rkpstaiked eeaselpdll istcgsveke tlqmyfeqft eqfelakhgn nswiltlcsr
      181 sdleeilgqk ehefgislav yrgggvgeql dprrfiltgf dgdtdcrmis lfigscsrtt
      241 ehtwetlded rivvsfrhdi dvrsflrkct skqlqgrdig vtrvertdsv lvqgdlekls
      301 edvltlyfsn tkrsrggdvq sctwinrrks avitfancdd ahavveqthn vcgtevhasl
      361 fysslqkalt gekpaltdqi stkvkvpvse ellrffetse rcrkqlesda krfhakvlvd
      421 rstaehelil emdvkkesla alqiaptwks ttlreiqsfl srydtaelta ekdvwtrsen
      481 icnglvtlnt alfysqinsk avitgekeev kvlsdkirtv lentaaavea ernstqvdiq
      541 ldcretcdli kervesrlgq vsfshdekqh iislrglkdq vdpvemiikq tqkniithql
      601 klsshlthfl ksldlkkfeq dyflpshipa rllkrqdffv ilvekenqkr aedriseilq
      661 eqvlqlspnq tgetwthflr nlqdeiellq kahdiritqs dneviicgfs savadvtgkv
      721 ktyldnkept tenvalksvr eaefvescln lcelpdlkrf gvtvlahrts dapclrvtap
      781 kdklrdavcv vqqqissill qshtygkage akvlekleas vktkakemqc slylsqehlv
      841 ksvppknfth kidnfmtlni tegdlhhyta daltcpmnts lafnnpvaqc fvqfggdtir
      901 evcraqqkhq pgdvvlsdag klsagtliya vfpqkgqkld shylqsavyn sllkaegegc
      961 asialpavgc gsfgfsvkes cvalraavlq fhqispknir hisvvdsder tveeynaliq
     1021 elgfpdttvv plpslklkhr sdtrvlingv qiflkkgdit ketvdfivns tnksldlntg
     1081 vsgailkaag qsvadeckkq aplkagaavl tgpgalqcky iaqmvgpest aditsslekv
     1141 lnlcedktat tlaipaigtg rggfppkesi kailsaiekh lkqpnssclr sisvvafeqk
     1201 tfddfrdhfk vwnkpasvkm penqvkigsv rievkkgdit netvrgivnt tnrdmslrgg
     1261 vsgaifkaag asveqecqkh gplqndipav tsggnlhcdf ivhmvgphsa aevrsrvknv
     1321 lerceekqit tvsfpavgtg aggvegedai gamlqgfedh lsqnistvik liyvvidrdn
     1381 vlqefqkglk twiantqdse dddewedyss tedssssdqg ananpvevlm gpikvkvfsg
     1441 ditkeiveai vnstttsldl ntgvsgailk asgqtvvnec kskgpqpadg liltkagnls
     1501 nikhiihmvg qtnekgisss mykvlrmcee nkiqsvsfpa lgtgagnlaa agaanamtea
     1561 ltnfmkdspk hlkrvhivif qakllpdfqq avkkckkisp nasarlvkpl qkpvipvptp
     1621 rpavclaket aavlfpvmav dvygtsptnl gkvkklldel vkeeciskdv qsshitdlpe
     1681 tdkkaivals ranqvsilvt swdtltvsgk rddvldavlk ingflqavrd remregevkr
     1741 lretlcweva rgdrweslep gisydielaf hrkqksfqyq eksetytvdf nkmevtnskl
     1801 escrikrtlm ggsdtaiihp pptwtkmdgr dleiitlqsd sveyknieta flkssihrdv
     1861 kpvkvqqidr iqsqsqwqry cvlkqavdkk yskqtnerql yhgttkdicq kinkngfnrs
     1921 fcgrnavvhg egtyfareaw yschdqysnp ddqqlkyiyr arvvtgslck srggmkepdp
     1981 inpadpragl hdcavddlkn pfifvvfcda gaypeylitf ksivlksp
//
LOCUS       XP_026128675             986 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 12-like [Carassius
            auratus].
ACCESSION   XP_026128675
VERSION     XP_026128675.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272890.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..986
                     /product="NACHT, LRR and PYD domains-containing protein
                     12-like"
                     /calculated_mol_wt=111526
     Region          94..164
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          175..342
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          419..479
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          481..619
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          677..974
                     /region_name="LRR_RI"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; cd00116"
                     /db_xref="CDD:238064"
     Site            order(684,687,689,692,694,713,716,718,721,741,744,746,749,
                     751,770,773,775,778,780,799,802,804,807,809,828,831,833,
                     836,838,856,859,861,864,866,885,888,890,893,895,914,917,
                     919,922,924,943,946,948,951,953,972)
                     /site_type="active"
                     /note="Leucine-rich repeats [active]"
                     /db_xref="CDD:238064"
     Region          685..712
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Site            order(690..691,748,806,835,892,918,920,947)
                     /site_type="other"
                     /note="Substrate binding site [chemical binding]"
                     /db_xref="CDD:238064"
     Region          713..736
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          741..769
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          770..798
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          799..822
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          828..855
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          856..884
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          885..913
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          914..942
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          943..964
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     CDS             1..986
                     /gene="LOC113109221"
                     /coded_by="XM_026272890.1:208..3168"
                     /db_xref="GeneID:113109221"
ORIGIN      
        1 medtqtstdq efspgcssvy qkrpepesrc vsvgsdtsmh hlvtfksgdi ktnlsyrseg
       61 esscvsmrsd asvpldymge etetdlrhev ldrfrsnllk kferlyegta tqrnptllne
      121 iytelyites esgeisnehe vrqietqsrr aatedtaikc sdifrplpgq dkairtvltk
      181 gvagigktvs vqklildwae gkenqdvqli fplpfreinl mkdktlslsd llhvflpetk
      241 eikissdeyk vlfifdglde crlsldfksk vklcnisesa svdellmnli vgnllpsali
      301 witsrpaaad lvpsecvhrv tevrgftepq keeyfrkris dqsladriis hlkssrslyi
      361 mchipvfcwi saavlekmls raesgeipkt ltqmythfli lqtnikheke yekkltdedm
      421 ilklgkvafe qlvkgnlify eedlrecgid vreasvysgl ctqifreelg lyqgkvfcfv
      481 hlsiqehlaa lyvhilfknd kyrnllepit kqsklkdwfq lnssehvsls elhqravdea
      541 lqsknghldl flrfllglsv eshqillqqi mtlkrsssdr nektveyikk kirtidspek
      601 sinlfhclne lgdhslveei qqylnsrrik eaklsssqws avafvlltse eelnefrldk
      661 fvkkknepen mkvlqkllpv ikesrsvqls ycsitdegca alasalrsnp shlreldlsw
      721 nkigksvnll fgvlqnphck leklwlrdcg itdegcsala salrsnpshl rqlglslnei
      781 gdlgvkylca gledprckle ilwlndcglt degcaalasa lrsnplhlre lsmtgnklgk
      841 svnllsdvlq hshcnleill lsycsipdeg ctalasalrs nsshlreldl ygnklgdsgv
      901 krlcaglkyp hckleilwln ncgvtdegca alaltltsnp shlreldlsg nklgksgvkl
      961 lsdlkddply klerfyycry iiikif
//
LOCUS       XP_026128676             736 aa            linear   VRT 18-JUN-2025
DEFINITION  protein NLRC3-like [Carassius auratus].
ACCESSION   XP_026128676
VERSION     XP_026128676.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272891.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..736
                     /product="protein NLRC3-like"
                     /calculated_mol_wt=83926
     Region          138..209
                     /region_name="FISNA"
                     /note="Fish-specific NACHT associated domain; pfam14484"
                     /db_xref="CDD:464185"
     Region          224..391
                     /region_name="NACHT"
                     /note="NACHT domain; pfam05729"
                     /db_xref="CDD:428606"
     Region          473..533
                     /region_name="NOD2_WH"
                     /note="NOD2 winged helix domain; pfam17779"
                     /db_xref="CDD:465501"
     Region          535..673
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     CDS             1..736
                     /gene="LOC113109222"
                     /coded_by="XM_026272891.1:204..2414"
                     /db_xref="GeneID:113109222"
ORIGIN      
        1 medtqtstdq efspgcssvd qkrseaessc vsvrsdasmd rplgfksrdt ktdlricsqr
       61 ssspdhscvs lksdesmrdp pnlsdeavts dpsradgers isggvssvfc lnntsvtasl
      121 nkhdqavnde lqrvkeqhkt smknkyerlc eglklqenes llnsiytqly iiegeregvn
      181 eehevlqmek tartqpsqda piycndifka saeagseeke qiktvltkgi agigktvsvq
      241 kfildwaegk anqdvdfmfv lpfrelnlir dhqyslhrll ldfhpelqdl dsqiyeeckv
      301 vfifdgldes ritlmfsdaq kvcdvtetss vavlmsklmk gellpsaliw itsrpaaanq
      361 ipseyihrlt eiqgftepqk eeyfrkrisd ehqasriish irrarslhim chipvfcwis
      421 stvlqkllee dlraeipqtl temyihflli qinmrkqkye erdpekllps nrevivklae
      481 vafkqlmkgn vmfyeedlie ssidvtdasv ysgicteifk qesvihqrkv ysfihlsvqe
      541 flaafylfyc cltknkktlt vdsesdfkyd msetdsdkvs lydlltsavy kalkskngrl
      601 dlflrfllgv slesnqrllq dllthtenss etisrttqdi kdkikssdhl sadqsinlfl
      661 cllevkdqtl freiqefvks dkhseeklsp ahcstisymi qmsekpldel npttyntsae
      721 grrrlipavi ncrkal
//
LOCUS       XP_026128682            1466 aa            linear   VRT 18-JUN-2025
DEFINITION  LOW QUALITY PROTEIN: nebulin-like [Carassius auratus].
ACCESSION   XP_026128682
VERSION     XP_026128682.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272897.1
KEYWORDS    RefSeq; corrected model; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio   :: 3% of CDS bases
            frameshifts :: corrected 1 indel
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1466
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1466
                     /product="LOW QUALITY PROTEIN: nebulin-like"
                     /calculated_mol_wt=168872
     Region          89..119
                     /region_name="NEBU"
                     /note="The Nebulin repeat is present also in Las1;
                     smart00227"
                     /db_xref="CDD:128523"
     Region          159..189
                     /region_name="NEBU"
                     /note="The Nebulin repeat is present also in Las1;
                     smart00227"
                     /db_xref="CDD:128523"
     Region          229..259
                     /region_name="NEBU"
                     /note="The Nebulin repeat is present also in Las1;
                     smart00227"
                     /db_xref="CDD:128523"
     Region          591..618
                     /region_name="Nebulin"
                     /note="Nebulin repeat; pfam00880"
                     /db_xref="CDD:459977"
     Region          652..682
                     /region_name="NEBU"
                     /note="The Nebulin repeat is present also in Las1;
                     smart00227"
                     /db_xref="CDD:128523"
     Region          835..862
                     /region_name="Nebulin"
                     /note="Nebulin repeat; pfam00880"
                     /db_xref="CDD:459977"
     Region          965..995
                     /region_name="NEBU"
                     /note="The Nebulin repeat is present also in Las1;
                     smart00227"
                     /db_xref="CDD:128523"
     Region          1079..1106
                     /region_name="Nebulin"
                     /note="Nebulin repeat; pfam00880"
                     /db_xref="CDD:459977"
     Region          1239..1268
                     /region_name="NEBU"
                     /note="The Nebulin repeat is present also in Las1;
                     smart00227"
                     /db_xref="CDD:128523"
     Region          1317..1344
                     /region_name="Nebulin"
                     /note="Nebulin repeat; pfam00880"
                     /db_xref="CDD:459977"
     CDS             1..1466
                     /gene="LOC113109269"
                     /coded_by="XM_026272897.1:238..4638"
                     /note="The sequence of the model RefSeq protein was
                     modified relative to its source genomic sequence to
                     represent the inferred CDS: inserted 1 base in 1 codon"
                     /db_xref="GeneID:113109269"
ORIGIN      
        1 maseeeyeee imeeyyyeeg ptvtttttsm shgvelgpgg lpkrtvrkkv kvdtskfmtp
       61 ylahsqkmld qyshnkyrea yekskgqpya isadtpemir ikkaqeqlse vkyrmeglka
      121 kttslydgea reiahvkhvs eliskvlyrq kwdetkdryl lppdapelvl avknaanysk
      181 klyteawded ktmyypysds pelrrvakaq hdlsdivykk ghnerkakyt cladppevel
      241 akknfanrsn lkyhedynkn vkgqwcetpy fdvavarmam dnisdkkyta dfedmkdqiy
      301 fmqtdtptya snkkareaas tvkykkdyek tkatsdynvl patenpllrq lryagtilsd
      361 kvykanyeks rgfsinycdt pkfkmdsvlk kfndirykek yenevkghyv gsyedvftvh
      421 cqkmeelknn qiykadyeda ktrcffpqtv tpeyeaskkl qqcqdkvyrq hpdkvkftqv
      481 tdspvqvqaa inakqlsdln ykekyekekf kcylpadypf fiqsrvnayn lsdtcykyew
      541 ekakakkfev kgdaisilaa rahtniasdv kykkeyeknr gqmigalsik ddpkmmhsvh
      601 vakiqserey kkdyekmktk yhttldmmlv tlakksqaia smtgyknipn ryllpydsip
      661 ldhakkanal qsdneyksdf nnyvkgtpwv pygsieaeks kkageilser kyrqhpdtvp
      721 ftsiddhplq lqakvnqmir sdlhykkgld kilqknslpp dvpeflqarc naynisdkcy
      781 klewlktiak gydlkpdais vkaakaarha asdvqykkky mkerghhvgf rslqddpllv
      841 hymevakiqs dklykkdyhk sklkyhtpvd mlsvaqakha skvqtyagyk qhfnhytllp
      901 damnlalars mnisssdvqy kqdydnyvkg tgwipigsld veraktaaaa lnekkyrqhp
      961 dtikftsvle tpvmeqakln aqqlsdrlyk asgekfmhty hlpadapell qakynavnis
     1021 nkyytyahkn dllkghhmkh daipivaaks srdiasdyky klayqkargh hvgfrslqdd
     1081 pllvhymeva kmqseknykk dyhksklkyh tpvdmlsvvq aknaskvqtn agykqhfhhy
     1141 tllpdamnve ltrnmmeiqs dnlyksdfnn yndtvkgmgw vpigslavet akvggrilse
     1201 hnyrthpsny kfhklmdsmd lhwlksyhaa wekdklkihv mpdspdivla kanalnmsqk
     1261 lykagleemn kkgydlkpda isivaakagr niasnykykl ayekakghhv gfrslqddpx
     1321 lvhymevaki qsernykkdy hksklkyhtp vdmlsvvqak taskvqtnag ykqhfhhytl
     1381 lpdamnlala rsmnvsssdv eykseynctr vmgmgcplvh ccrdckeagh gtvapsglpv
     1441 cpepkshrsp rcavdrcfer rnaapc
//
LOCUS       XP_026128683             764 aa            linear   VRT 18-JUN-2025
DEFINITION  neural cell adhesion molecule 2-like [Carassius auratus].
ACCESSION   XP_026128683
VERSION     XP_026128683.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272898.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 1% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..764
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..764
                     /product="neural cell adhesion molecule 2-like"
                     /calculated_mol_wt=85295
     Region          4..82
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          4..11
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          19..23
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          45..49
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          59..64
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          73..76
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          91..157
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          101..105
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          114..118
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          151..156
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          183..266
                     /region_name="IgI_1_MuSK"
                     /note="agrin-responsive first immunoglobulin-like domains
                     (Ig1) of the MuSK ectodomain; a member of the I-set of
                     IgSF domains; cd20970"
                     /db_xref="CDD:409562"
     Region          185..190
                     /region_name="Ig strand A'"
                     /note="Ig strand A' [structural motif]"
                     /db_xref="CDD:409562"
     Region          196..203
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409562"
     Region          209..214
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409562"
     Region          216..218
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409562"
     Region          225..228
                     /region_name="Ig strand D"
                     /note="Ig strand D [structural motif]"
                     /db_xref="CDD:409562"
     Region          232..238
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409562"
     Region          245..252
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409562"
     Region          258..266
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409562"
     Region          268..365
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          286..290
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          299..303
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          331..335
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          345..350
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          358..361
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          381..458
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     Region          386..390
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          399..403
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          426..430
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          440..445
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          <457..>647
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain [General function
                     prediction only]; COG3401"
                     /db_xref="CDD:442628"
     Region          464..556
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(464,529,544)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(545..546,548..549)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     CDS             1..764
                     /gene="LOC113109270"
                     /coded_by="XM_026272898.1:1..2295"
                     /db_xref="GeneID:113109270"
ORIGIN      
        1 mtvkyfflcv clvigepvsl dwykpqgerm vpsqrvalhn egvrsrltly nakiedagiy
       61 rcqandaqgh tqeatvvlei yqkltfrdvr spqefrqgdv aevvcdvtss pvpvvswfyn
      121 nveiiedtek fqllqnnnlq vqrvtkadeg vyrcearvea rgeidfrdii lvvnvppvvs
      181 vpqqsfnata dygesvtftc raygspepdv twhrkgvqlq eseryemrar gttltvrniq
      241 qddggsytck afnkageveh elflkvfvqp hitklrnvta vegsaamisc kaegeplpei
      301 swrrasdghs fsdgdkspdg rvevrgryge smltivgvel sdwgrfdcea lsrigghqks
      361 mfldieyapk fqtnhtiffs wegnpvnisc dvmsnppatm lwrrekltip segagnmrvy
      421 sapgrsllev tpmsdrdfgr ynctarnnig mrfqefilaq advpsnpysv rlssvaqrva
      481 tvtftkpdsh ggvpishylv kykdissqaw kdvksqgmqt vvlltnlepn ttyevrvaav
      541 ngkgqgefsr tesfqtlpir epsppsvqgq rgvgkayrlg lvkqddggmp ileyivkykt
      601 dkeeqwmtkl vpgvndfvll qslqwntqye veitarnvkg lseptfvkfs mpqkpditds
      661 lfsglglgav vglglaglll llvlvdvscf flrqcgllmc itrklcskkt atsgkskele
      721 egkaaylklp lkeengketl kpdtieikvh gdnslhmtqe dska
//
LOCUS       XP_026128684             203 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109271 [Carassius auratus].
ACCESSION   XP_026128684
VERSION     XP_026128684.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272899.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 1% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..203
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..203
                     /product="uncharacterized protein LOC113109271"
                     /calculated_mol_wt=22877
     CDS             1..203
                     /gene="LOC113109271"
                     /coded_by="XM_026272899.1:139..750"
                     /db_xref="GeneID:113109271"
ORIGIN      
        1 mrkflflvlt itasvafasp pvqdeklpdp vvkvpvveke pneehteaea gplvqdeava
       61 dsrlepdsvl lepetteeqr lpeetqamle klvleadnlt eeivetelgp elettdfqkd
      121 sniipelese tnteeedeke enlvkeeptl eadymmdenp eiqmdpgrqs rmtqngwgtc
      181 rgvvlqgkcy qyfrvhlnay qaa
//
LOCUS       XP_026128685             227 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109272 [Carassius auratus].
ACCESSION   XP_026128685
VERSION     XP_026128685.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272900.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..227
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..227
                     /product="uncharacterized protein LOC113109272"
                     /calculated_mol_wt=25710
     CDS             1..227
                     /gene="LOC113109272"
                     /coded_by="XM_026272900.1:43..726"
                     /db_xref="GeneID:113109272"
ORIGIN      
        1 maavsltdpl ckpssysphf kvevcvkkpl mpvhlsseqv alemlclcsq ldlliraqvh
       61 qfqeqlkqdt speeskcfqk qgaeiiyqmn qclehlnepv lqleeyldvv glsalfprve
      121 vymihgspid mlerppsday fphigrlnql lvlsqqlded vkhlgshkyi ahqlsaiyqv
      181 lnslkdilpl siirkdiean fkqlkkslti eegskldpql padrvsw
//
LOCUS       XP_026128686             253 aa            linear   VRT 18-JUN-2025
DEFINITION  lysosome-associated membrane glycoprotein 1-like [Carassius
            auratus].
ACCESSION   XP_026128686
VERSION     XP_026128686.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272901.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 9% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..253
                     /product="lysosome-associated membrane glycoprotein
                     1-like"
                     /calculated_mol_wt=27207
     Region          54..202
                     /region_name="Lamp"
                     /note="Lysosome-associated membrane glycoprotein (Lamp);
                     pfam01299"
                     /db_xref="CDD:460152"
     Region          218..247
                     /region_name="TM_EGFR-like"
                     /note="Transmembrane domain of the Epidermal Growth Factor
                     Receptor family of Protein Tyrosine Kinases; cd12087"
                     /db_xref="CDD:213052"
     Site            order(218..219,222..223,225..227,229..230,233)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:213052"
     CDS             1..253
                     /gene="LOC113109274"
                     /coded_by="XM_026272901.1:1..762"
                     /db_xref="GeneID:113109274"
ORIGIN      
        1 mipvireqnm lsatifrmll altihhtlta dvpptgvape tssppaspat pgppergsyn
       61 vtnssdavcl larmglqlni sfisspydkt vqevlnvhpn lvkssgscdp dsatlmlted
      121 nitltfsfsl nstsnkyhls glelsaafpd vakrlvfrnt slnymvgtlg hsymcqkekt
      181 lsvtqdfsln tfqlqvqpfg vsgdfgaaee cdldeddmli piivgaalav lvlivilayl
      241 igrkrshagy qti
//
LOCUS       XP_026128687             151 aa            linear   VRT 18-JUN-2025
DEFINITION  T-cell surface glycoprotein CD3 zeta chain-like [Carassius
            auratus].
ACCESSION   XP_026128687
VERSION     XP_026128687.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272902.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 8% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..151
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..151
                     /product="T-cell surface glycoprotein CD3 zeta chain-like"
                     /calculated_mol_wt=17748
     Region          19..48
                     /region_name="TCR_zetazeta"
                     /note="T-cell surface glycoprotein CD3 zeta chain;
                     pfam11628"
                     /db_xref="CDD:463313"
     CDS             1..151
                     /gene="LOC113109275"
                     /coded_by="XM_026272902.1:1..456"
                     /db_xref="GeneID:113109275"
ORIGIN      
        1 milqkksafy pdealsvfdp tycyifdvfl llysviftal yfrekftree pvppepapla
       61 rnpnepvytd ldlpqmssdy qqldrpirrr epethyqelr ahtsdeyqai rtkgakprks
      121 krksnegrtr rngdaaesme metyptemlh y
//
LOCUS       XP_026128689             154 aa            linear   VRT 18-JUN-2025
DEFINITION  FUN14 domain-containing protein 1 [Carassius auratus].
ACCESSION   XP_026128689
VERSION     XP_026128689.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272904.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 5% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..154
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..154
                     /product="FUN14 domain-containing protein 1"
                     /calculated_mol_wt=16773
     Region          53..>106
                     /region_name="FUN14"
                     /note="FUN14 family; pfam04930"
                     /db_xref="CDD:461487"
     CDS             1..154
                     /gene="LOC113109278"
                     /coded_by="XM_026272904.1:1..465"
                     /db_xref="GeneID:113109278"
ORIGIN      
        1 madrgedvda esedelyevv nitdyarrhq wwslvfgnst gpiaekysva sqimmggvtg
       61 wctgylfqrv gkivatavgg gflllqianh sgyvqvdwkk vekdvnkakk hlkkkankaa
      121 pelssfiees tefvkrnivi sggfvggfll glas
//
LOCUS       XP_026128690             419 aa            linear   VRT 18-JUN-2025
DEFINITION  actin-fragmin kinase-like [Carassius auratus].
ACCESSION   XP_026128690
VERSION     XP_026128690.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272905.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 8% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..419
                     /product="actin-fragmin kinase-like"
                     /calculated_mol_wt=47199
     Region          10..276
                     /region_name="NanM"
                     /note="N-acetylneuraminic acid mutarotase [Cell
                     wall/membrane/envelope biogenesis]; COG3055"
                     /db_xref="CDD:442289"
     Region          23..69
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          73..128
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          131..174
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          182..228
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     Region          231..276
                     /region_name="KELCH repeat"
                     /note="KELCH repeat [structural motif]"
                     /db_xref="CDD:276965"
     CDS             1..419
                     /gene="LOC113109279"
                     /coded_by="XM_026272905.1:111..1370"
                     /db_xref="GeneID:113109279"
ORIGIN      
        1 mnqgssaclw tsvpqhcpap cdrykhasca hrgyvyvlsg rerhllrdfw kynvvcdkwa
       61 elpcdseeap eeleehtmva yqgflyvfgg mqdssytksi mplwvfdtvk dswinwktgs
      121 etsqgvipan rkghsavifg ssmyvyggyi dmrgstkefw kfdfdsrvws llssveggpg
      181 prhghsamty qdsmylyggl qglreqkdlw swssasqtws cinfhsgpsr lvghsavlfk
      241 dsmlifggge tqsspqsslw rfnlttktwk klgllpgsps lcrihhcsig igqsfqptsp
      301 nsiylrkipn shniynqlrp fknkcqpsra slqepcielq tfhmdrkkyl sdlsiavtdt
      361 klkgtcltqe aisekrnsgd laeeteddmf lrmpdvllvl ggkplqgphv isvwhmtma
//
LOCUS       XP_026128691             426 aa            linear   VRT 18-JUN-2025
DEFINITION  disrupted in renal carcinoma protein 2-like [Carassius auratus].
ACCESSION   XP_026128691
VERSION     XP_026128691.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272906.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 1% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..426
                     /product="disrupted in renal carcinoma protein 2-like"
                     /calculated_mol_wt=46395
     Region          34..425
                     /region_name="MFS_DIRC2"
                     /note="Disrupted in renal carcinoma protein 2 of the Major
                     Facilitator Superfamily of transporters; cd17397"
                     /db_xref="CDD:340955"
     Site            order(49..50,53..54,57,88,143..144,146..148,151,171,
                     174..175,178,272,275..276,279..281,284,311,315,375..376,
                     380,384,400,403..404,407..408,411)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340955"
     CDS             1..426
                     /gene="LOC113109280"
                     /coded_by="XM_026272906.1:142..1422"
                     /db_xref="GeneID:113109280"
ORIGIN      
        1 mgavestege repllvpsqp atntqpvlsr vygrrwfvlt mfsllgfmqg lvwntwgpiq
       61 vsakhvfefs ptdiavlvmw gpvgylpwll fmwlmdkkgl raslllsaff mllgaalrsv
      121 plkdlyyrrw mihggqllng lagptimsag pllsttwfap dqratataia sligylgsaf
      181 afligplavp apngtvgstv ywnqnhigdr iqfvlyaevg miaalfvavl fyfpsrppip
      241 psvaaasqrl syrssicrll snmrflmial aysvptgvva gwagvldmil tpakvsqvda
      301 gwigfwsivg gcvfgvamar fadyirgmlk lilvlmfaga slaatwftlt cltrlthlps
      361 tqatlytsci lvgifinssv piflelfiet vypvpegitc gvvtflsnlf tglllfcltf
      421 yftgsp
//
LOCUS       XP_026128692             382 aa            linear   VRT 18-JUN-2025
DEFINITION  NACHT, LRR and PYD domains-containing protein 3-like [Carassius
            auratus].
ACCESSION   XP_026128692
VERSION     XP_026128692.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272907.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 2% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..382
                     /product="NACHT, LRR and PYD domains-containing protein
                     3-like"
                     /calculated_mol_wt=43508
     Region          42..203
                     /region_name="NLRC4_HD2"
                     /note="NLRC4 helical domain HD2; pfam17776"
                     /db_xref="CDD:465499"
     Region          <238..>368
                     /region_name="PPP1R42"
                     /note="protein phosphatase 1 regulatory subunit 42;
                     cl42388"
                     /db_xref="CDD:455733"
     Region          290..318
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     Region          319..347
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     Region          348..359
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     CDS             1..382
                     /gene="LOC113109283"
                     /coded_by="XM_026272907.1:1..1149"
                     /db_xref="GeneID:113109283"
ORIGIN      
        1 mfqsliessi dvtdasvysg icteifkqes vihqrkvysf ihlsvqefla afyllycclt
       61 knkktlrefr lnrsykvsly dlltsavdka vesknghldl flrfllgvsl esnqrllqdl
      121 lthtensses isrttqyike kikydpdddd gggelyvdki dllkkkqqkg hkkinldgnl
      181 sagesinlfl cllevkdqtl freiqefvks dkhteklsaa hcstisymiq mseepldeld
      241 tmkyntsaeg rrrlipavin crkallrycd vtdegcsalt salrsnpshl reldlsenki
      301 rdlgvkrlca gledphckle klwlrdcgvt degcsalasa lrsnpshlre lnlsrnklrl
      361 sgvkllsdlk ddprykleil yy
//
LOCUS       XP_026128693            1563 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109284 [Carassius auratus].
ACCESSION   XP_026128693
VERSION     XP_026128693.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272908.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 1% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..1563
                     /product="uncharacterized protein LOC113109284"
                     /calculated_mol_wt=176243
     Region          963..1179
                     /region_name="RT_pepA17"
                     /note="Reverse transcriptase (RTs) in retrotransposons.
                     This subfamily represents the RT domain of a
                     multifunctional enzyme. C-terminal to the RT domain is a
                     domain homologous to aspartic proteinases (corresponding
                     to Merops family A17) encoded by...; cd01644"
                     /db_xref="CDD:238822"
     Site            order(1022..1027,1063..1064,1099,1101..1102,1170..1171)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:238822"
     Site            order(1022..1027,1063,1101)
                     /site_type="other"
                     /note="putative NTP binding site [chemical binding]"
                     /db_xref="CDD:238822"
     Site            1064
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:238822"
     Region          1194..1359
                     /region_name="Peptidase_A17"
                     /note="Pao retrotransposon peptidase; pfam05380"
                     /db_xref="CDD:461634"
     CDS             1..1563
                     /gene="LOC113109284"
                     /coded_by="XM_026272908.1:423..5114"
                     /db_xref="GeneID:113109284"
ORIGIN      
        1 mesdeemypd vrpkrqirrp vrlqdfevdy mgyshrdqhq wglsspaldr rafpfqtayp
       61 hssgfsgnaa hpefpqlapd hsqrrdldgl sqpartpssh qspyldsrfs eeiraireen
      121 tkllqtqqaf qtgikelnea rremkellev arslradlaq vnsptsnysn ptspqadava
      181 srsfavaahs kemeqedwpd pppwpepeen vsrgmcnlrv deqeldnihh nlspearvcr
      241 pckpplppqy papttdkgis pylstrpsql lthpapahap vmqsaparty hplaatgavh
      301 gmpppnqlmq ppgneqvyrg pqptipkfih pdpsefarlr ialenllpsn atelfkyqil
      361 vdhlkleeak liadaylnsp npysdtmsal hdkfghphql alkkiasvle tpevrrgdtm
      421 afqkfslqiq slvgllrtlg pegeielncg shvarllskl ppeqradfrr hqfkqlgath
      481 tlhdlaewlr yeswsqgfds qatgcsiker qnlktdgrpg rqtvtvlhga gesretasly
      541 qkesstsrgv kskaycayce stehylsqcs avtklskdql rewirvnkrc wrcarthqaa
      601 qctlkkpcni cqgkhllalh eintraergn kdvavkeesc ltssaadsly ldrpgagnrv
      661 mlkvvpvlvh yedrtldtfa ilddgsertm llpaaakflg ikgtpealpl rtvrqdiqil
      721 hghtvsfhvs paanphtsyk ingaftagrl slaqhtypid rlkrkykyls giplpalrda
      781 qptllvgsdn pqlitpvepv rlgppggpaa vctrlgwtlq gptpfrgrpi qpaqclftss
      841 appmdelykh verlwqvdtv pyrherevtr skldqqaval leaktvrtnv dgilryatpl
      901 lrhpsmpplh spkesvmpml rsterrllkd pkladaykme mqklietgav revteetstk
      961 egwyishhlv shngknrlvf ncshqylgqt lnqyllpgpt lgapllgvll rfrerpiavs
     1021 gdikgmfhqv rlipedrhll rflwrdlkve etprtfewqv lpfgttcspc caiyalqrhv
     1081 vdhcqpdddl rfsvencfyv dnclqsvstq seakllvdrl rdllisagfe lrqwacnnpd
     1141 vlshlpqear sesldlwlaq dksnplestl glswnwatds lgykhrpvsy evptlrniyr
     1201 vlatqydplg ymlpfstrak liirqlwdkk rgwddsnlpa ellqawsswe aeleslpflt
     1261 fprayvpada nlegatrevh ifadaseqay gavaymrted regqihlsfi larsrvaprr
     1321 lhsiprlelc galvaaqlah vlerelsltv artvlwsdst tvltwlhsqs crykvfvgar
     1381 iaeiqeltek ctwryvdsan npaddltrgk tlealidpnr wsqgppfllq npatwperps
     1441 tepfednvel rkttfcgvti tspisisrdd kvyqtwqeli dataleilgp npssstpnae
     1501 eyqqaerivl qraqrqsfpe dykllaagkp vspgsrlltl apeldrstdl irvggrlrrl
     1561 gsl
//
LOCUS       XP_026128694             329 aa            linear   VRT 18-JUN-2025
DEFINITION  interleukin-1 receptor type 2-like [Carassius auratus].
ACCESSION   XP_026128694
VERSION     XP_026128694.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272909.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 3% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..329
                     /product="interleukin-1 receptor type 2-like"
                     /calculated_mol_wt=37292
     Region          <53..>103
                     /region_name="Ig_6"
                     /note="Immunoglobulin domain; pfam18452"
                     /db_xref="CDD:465773"
     Region          227..313
                     /region_name="IG_like"
                     /note="Immunoglobulin like; smart00410"
                     /db_xref="CDD:214653"
     CDS             1..329
                     /gene="LOC113109285"
                     /coded_by="XM_026272909.1:1..990"
                     /db_xref="GeneID:113109285"
ORIGIN      
        1 mdpkfqsvkf gpcfktvisp ilakcikifp lqgsetqyte lktyftsagl afklecsetp
       61 nvswsrfpnq rlegisgini qggalwflpa dlshsgsysc ltrygnetwt tifyvsvenk
      121 tcpklnrkde itrikeipcl lphifeidpq aqvtwrnnch plnvtnskvl pinrskhmfg
      181 lyscfvsftf ggqhysaaqt teiysrskdy vvtkpeiiyp keetkkvtlg esytlncevl
      241 igkndsgetv irwdtdlknl eldynisivk kgewdymlyt lyipevteeh lytnftcvvk
      301 hprgsdsgnv llipvsqneg yycigvglv
//
LOCUS       XP_026128696             269 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein C13orf42-like [Carassius auratus].
ACCESSION   XP_026128696
VERSION     XP_026128696.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272911.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..269
                     /product="uncharacterized protein C13orf42-like"
                     /calculated_mol_wt=30470
     CDS             1..269
                     /gene="LOC113109287"
                     /coded_by="XM_026272911.1:420..1229"
                     /db_xref="GeneID:113109287"
ORIGIN      
        1 mfkkinavfr pnhlgprsrd rfrpdedyhs actvklvrst smlvvgessh apqdstlkrs
       61 vsavsvqtst alyyyqsred qvwlysqnqn cleylqelva lrrqytksis dlknserket
      121 asrkkkpapr ppqnraaqts rpgpsappip needtlqffd aviascdpep srkphvdngh
      181 advdfivats tsehdlhsnw vlrdphrism tesqpknsei shrqvaqqkg vmgstgsrrc
      241 lqrnpihlpk vvesafqtlr fkpklkkkd
//
LOCUS       XP_026128697              79 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc-binding protein A33-like [Carassius auratus].
ACCESSION   XP_026128697
VERSION     XP_026128697.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272912.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..79
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..79
                     /product="zinc-binding protein A33-like"
                     /calculated_mol_wt=8665
     Region          12..>71
                     /region_name="SPRY"
                     /note="SPRY domain; cl02614"
                     /db_xref="CDD:470632"
     CDS             1..79
                     /gene="LOC113109288"
                     /coded_by="XM_026272912.1:81..320"
                     /db_xref="GeneID:113109288"
ORIGIN      
        1 mqkmlktvdy tpvtfdpnta hcniilsedl tsgrysdeeq tpenperfdm sacvvcsqgf
       61 dsgshcwdve vetqagsse
//
LOCUS       XP_026128698             183 aa            linear   VRT 18-JUN-2025
DEFINITION  protein jagunal homolog 1-A [Carassius auratus].
ACCESSION   XP_026128698
VERSION     XP_026128698.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272913.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..183
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..183
                     /product="protein jagunal homolog 1-A"
                     /calculated_mol_wt=20553
     Region          1..177
                     /region_name="Jagunal"
                     /note="ER re-organization during oogenesis; pfam07086"
                     /db_xref="CDD:462086"
     CDS             1..183
                     /gene="LOC113109290"
                     /coded_by="XM_026272913.1:172..723"
                     /db_xref="GeneID:113109290"
ORIGIN      
        1 masrtgpraa gtdgsdfkhr ekvashyqms aslkseikkl tvvhffiwil vaaqvavsql
       61 nlvshdlvam pyqweypyll sllpsligal ampknnisyl vismisaglf svaplifgam
      121 emfplaqqly rhgkayrfif gfsavsvmyl lmviaiqvha wqiyyskkll dawfnstqek
      181 kkk
//
LOCUS       XP_026128699             106 aa            linear   VRT 18-JUN-2025
DEFINITION  synapsin-2-like [Carassius auratus].
ACCESSION   XP_026128699
VERSION     XP_026128699.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272914.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..106
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..106
                     /product="synapsin-2-like"
                     /calculated_mol_wt=11385
     Region          1..27
                     /region_name="Synapsin_N"
                     /note="Synapsin N-terminal; pfam10581"
                     /db_xref="CDD:463155"
     CDS             1..106
                     /gene="LOC113109291"
                     /coded_by="XM_026272914.1:235..555"
                     /db_xref="GeneID:113109291"
ORIGIN      
        1 mnylrrrlsd stfisnlpng ymsdlqkpdp pqppppgpas gpapvspgqe rkpiqpqpvg
       61 tgffssitsv vkqtaasagl veqtpvpasf krhkillvid epqrdw
//
LOCUS       XP_026128701             349 aa            linear   VRT 18-JUN-2025
DEFINITION  growth hormone-regulated TBC protein 1-A-like [Carassius auratus].
ACCESSION   XP_026128701
VERSION     XP_026128701.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272916.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..349
                     /product="growth hormone-regulated TBC protein 1-A-like"
                     /calculated_mol_wt=40716
     Region          79..291
                     /region_name="TBC"
                     /note="Domain in Tre-2, BUB2p, and Cdc16p. Probable
                     Rab-GAPs; smart00164"
                     /db_xref="CDD:214540"
     CDS             1..349
                     /gene="LOC113109294"
                     /coded_by="XM_026272916.1:21..1070"
                     /db_xref="GeneID:113109294"
ORIGIN      
        1 meetqnmenh fndsassdsn dcqrvdqygf eraedfnyes yedfmsrhla vvtrrskkwt
       61 kllqgtvkve knikvkryvr kgvpcehrtq iwmaasgaqd qldrnpgyyh sllkaehdpk
      121 ieeviradmh rtfpdniqfr assepclqka lfnvllaygy hnkdvgycqg mnfiagylli
      181 itkdeeksfw lmdaligkil pdyytptmlg lqmdqevlge lvrmkvpavw qvmnrhnvmw
      241 tlvvsrwfic lyvdilpvet vlriwdclfy egskilfrva ltmirhnenl isqaqslsei
      301 cerfkqithg eyvedchtfm qkifmepggl statitklrk mcrnritsa
//
LOCUS       XP_026128702             470 aa            linear   VRT 18-JUN-2025
DEFINITION  nyctalopin-like [Carassius auratus].
ACCESSION   XP_026128702
VERSION     XP_026128702.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272917.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..470
                     /product="nyctalopin-like"
                     /calculated_mol_wt=53237
     Region          65..>331
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          65..84
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          85..108
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          109..133
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          134..180
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          181..204
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          205..228
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          229..252
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          253..276
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          277..300
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          282..>399
                     /region_name="PCC"
                     /note="polycystin cation channel protein; TIGR00864"
                     /db_xref="CDD:188093"
     Region          301..320
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     CDS             1..470
                     /gene="LOC113109296"
                     /coded_by="XM_026272917.1:1..1413"
                     /db_xref="GeneID:113109296"
ORIGIN      
        1 mcsiiiavyf llfllpphal alwactrscp psctctqeks csvlcdhvsm mdlpkefpce
       61 aasinldkns ikflserafg tlpslktlsl nhnnisfitp gafkglpnll elklahneyi
      121 rylhtrsfta lkrlvrldls dcnlfsmpdr ifleqislke llcfqnnfrr vpgalrgmen
      181 lthvylernk ieavaynsll gltnlkylnl qenrinvihd eafkdlvrle nfylndnllv
      241 dlpqqafkgl snlkmlnlgg nmltnvskaw fsdlvelevl yldrnrlsyi eegafenlts
      301 litlhlnsnn ltslpfsvfq piyligrlyl frnpwectcd lewlrewmes yklvrdipca
      361 spssvagldl sevvfahlng tcldppelnl tttlpenstv enkfssfisk lleqelreem
      421 vnitdglrng tqqdpaesqv ssgrglfgap rsvfllvilf qvqidcinas
//
LOCUS       XP_026128704             480 aa            linear   VRT 18-JUN-2025
DEFINITION  putative sodium-coupled neutral amino acid transporter 11
            [Carassius auratus].
ACCESSION   XP_026128704
VERSION     XP_026128704.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272919.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..480
                     /product="putative sodium-coupled neutral amino acid
                     transporter 11"
                     /calculated_mol_wt=51968
     Region          49..437
                     /region_name="SLC5-6-like_sbd"
                     /note="Solute carrier families 5 and 6-like; solute
                     binding domain; cl00456"
                     /db_xref="CDD:444915"
     CDS             1..480
                     /gene="slc38a11"
                     /coded_by="XM_026272919.1:246..1688"
                     /db_xref="GeneID:113109299"
ORIGIN      
        1 mgnihlvqqg isegmlenhr teeksgtvqe mdsdrdclls shkdmekrgt ssissasfnf
       61 insiigsgii glpyalsqag lpmgllllvl vafitdysii llvrggnlsg thsyqslvqs
      121 tfgqigylvv salqflypfi amisyniitg dtltkvfmri qgvgpgnilt erhfvimmst
      181 llftlplsly kdiaklgkvs llsmlltlai litvvvraat lgpqipasdd awvfarwnai
      241 qavavmsfaf ichhnsfmiy gslreptlsg wslvthvsvg savlvsavfa aagymtftgy
      301 tqgdifenyc rndnlatfgr fcygisiitt fplecfvtre visnvffkge lsntthviit
      361 lvivsaatvl slsydclgiv lelngvlsai plmfifpaac flklsdgrwf rgenlipsii
      421 laagvcvmii glimmvlfpq dcshgaelfy csvsntsvps ttspnsglqf inatqnisif
//
LOCUS       XP_026128705             342 aa            linear   VRT 18-JUN-2025
DEFINITION  Bardet-Biedl syndrome 5 protein homolog [Carassius auratus].
ACCESSION   XP_026128705
VERSION     XP_026128705.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272920.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..342
                     /product="Bardet-Biedl syndrome 5 protein homolog"
                     /calculated_mol_wt=38852
     Region          8..340
                     /region_name="BBL5"
                     /note="Bardet-Biedl syndrome 5 protein; pfam07289"
                     /db_xref="CDD:462136"
     CDS             1..342
                     /gene="LOC113109300"
                     /coded_by="XM_026272920.1:144..1172"
                     /db_xref="GeneID:113109300"
ORIGIN      
        1 masvfdvlwe drdvrfditp qqmktrpgea lidcldsied tkgnngdrgr llvtnlriiw
       61 hslalprvnl svgynciini ttrtansklr gqtealyilt ksnntrfefi ftnvvpgspr
      121 lftsviavhr ayetskmyrd lklrgaliqn kqlrllpqeq vydkingvwn lssdqgnlgt
      181 ffitnvrivw hanmnesfnv sipylqirsi rirdskfgha lviessqqtg gyvlgfkidp
      241 tdklqdavke inslhkvysa npifgveyem eekpqpleel tvdqppddve iepdehtdaf
      301 tayfadgnkq hdrepvfsee lglaieklkd gftlqglwev mg
//
LOCUS       XP_026128706             207 aa            linear   VRT 18-JUN-2025
DEFINITION  methyltransferase-like protein 5 [Carassius auratus].
ACCESSION   XP_026128706
VERSION     XP_026128706.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272921.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..207
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..207
                     /product="methyltransferase-like protein 5"
                     /calculated_mol_wt=22978
     Region          4..205
                     /region_name="COG2263"
                     /note="Predicted RNA methylase [General function
                     prediction only]"
                     /db_xref="CDD:441864"
     CDS             1..207
                     /gene="LOC113109301"
                     /coded_by="XM_026272921.1:220..843"
                     /db_xref="GeneID:113109301"
ORIGIN      
        1 mklkelescl qqvdgfeepk illeqyptsp hiagcmlyti hntfddiqnk lvadlgcgcg
       61 vlsvgaavld aglcvgfdid edaldifkgn vddfelsnid mvqcdvcsig ssyakkfdtv
      121 imnppfgtkh nqgidmqflr taismastav yslhktstrd hiqkkaddwk vkmeviaelr
      181 ydlpasykfh kkksvdiqvd firltlt
//
LOCUS       XP_026128707             213 aa            linear   VRT 18-JUN-2025
DEFINITION  dual specificity protein phosphatase 19-like [Carassius auratus].
ACCESSION   XP_026128707
VERSION     XP_026128707.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272922.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..213
                     /product="dual specificity protein phosphatase 19-like"
                     /calculated_mol_wt=23546
     Region          64..199
                     /region_name="PTP_DSP_cys"
                     /note="cys-based protein tyrosine phosphatase and
                     dual-specificity phosphatase superfamily; cl28904"
                     /db_xref="CDD:475123"
     CDS             1..213
                     /gene="LOC113109302"
                     /coded_by="XM_026272922.1:445..1086"
                     /db_xref="GeneID:113109302"
ORIGIN      
        1 mqslaqeiks fskanlrkqc trvttlsgrr iietwkgstv qvveetvqpe tacgyvqdnn
       61 wdlqvgyvkp ylllgsqdaa hhfgtlrkyk vthilnvayg venafpdlfi yktlsildvp
      121 dtdiishiee caqfidqaka ekgvvlvhcn sgvsrsvsvv igylmlkenq pfgdtfalvk
      181 sarpascpnp gfmeqlknfr pqeatqangl ghd
//
LOCUS       XP_026128708             533 aa            linear   VRT 18-JUN-2025
DEFINITION  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like
            [Carassius auratus].
ACCESSION   XP_026128708
VERSION     XP_026128708.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272923.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..533
                     /product="high affinity cGMP-specific 3',5'-cyclic
                     phosphodiesterase 9A-like"
                     /calculated_mol_wt=61648
     Region          250..478
                     /region_name="PDEase_I"
                     /note="3'5'-cyclic nucleotide phosphodiesterase;
                     pfam00233"
                     /db_xref="CDD:459723"
     CDS             1..533
                     /gene="LOC113109303"
                     /coded_by="XM_026272923.1:347..1948"
                     /db_xref="GeneID:113109303"
ORIGIN      
        1 matkiiyftv ngrpeqaefp tdcpaqdvkd lfrsaaeagp hdilklyntn gsiinispql
       61 apnsphscyk levvaadcns ellgsdpava lgfdlfsmek rlqslekril teaaetpaiv
      121 yemkrqvesf reklesvehl swlglfkdms egthkpspfy hkrtlrktre ecehvrekfl
      181 qmsslevsee vrqylktptf dnwqwedaei mvllqvmytd ldfistfnie ldvlqqflye
      241 vyrrynnipf hnfkhcfcvt qmmygliwlt dlrskidsid llimltsaic hdldhtgynn
      301 ayqinartel alryndispl enhhcavafe ileksesnif rnlpteqykr iregiikcil
      361 atdmtrhtei lnkfkailpv fdfsnkdhrd vlmmilikvs disnearpmd vaepwldcll
      421 qeffnqsdme kleglpvtpf mdrdkvtkps sqtgfirfvl fplfielanl fpcleqhiid
      481 pvrkaldyyt emekalerek qnraqsdkvv kpstskepea hpdpggttkp vtl
//
LOCUS       XP_026128710             152 aa            linear   VRT 18-JUN-2025
DEFINITION  ladderlectin [Carassius auratus].
ACCESSION   XP_026128710
VERSION     XP_026128710.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272925.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..152
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..152
                     /product="ladderlectin"
                     /calculated_mol_wt=16999
     Region          27..148
                     /region_name="CLECT"
                     /note="C-type lectin (CTL)/C-type lectin-like (CTLD)
                     domain; cl02432"
                     /db_xref="CDD:470576"
     Site            order(122,126,128,134,136..139,142..144)
                     /site_type="other"
                     /note="ligand binding surface [chemical binding]"
                     /db_xref="CDD:153059"
     CDS             1..152
                     /gene="LOC113109305"
                     /coded_by="XM_026272925.1:107..565"
                     /db_xref="GeneID:113109305"
ORIGIN      
        1 mamlrnllll fivfsmgnad vdvdekcpfg wtnfgvqcyk fvsqsvnwit aerscqslda
       61 nlasvhskpe ndfllslips sstrcwlgah dgvqegqwlw sdgtpydyts wcsnepnnln
      121 tencgeinwt snrcwndisc stsmgyicak dl
//
LOCUS       XP_026128711             150 aa            linear   VRT 18-JUN-2025
DEFINITION  galactose-specific lectin nattectin-like [Carassius auratus].
ACCESSION   XP_026128711
VERSION     XP_026128711.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272926.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..150
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..150
                     /product="galactose-specific lectin nattectin-like"
                     /calculated_mol_wt=16790
     Region          27..146
                     /region_name="CLECT"
                     /note="C-type lectin (CTL) or carbohydrate-recognition
                     domain (CRD); smart00034"
                     /db_xref="CDD:214480"
     Site            order(121,125,127,134..137,140..142)
                     /site_type="other"
                     /note="ligand binding surface [chemical binding]"
                     /db_xref="CDD:153059"
     CDS             1..150
                     /gene="LOC113109306"
                     /coded_by="XM_026272926.1:122..574"
                     /db_xref="GeneID:113109306"
ORIGIN      
        1 mpmlrsllll livfsmenee vnavkkcpfg wknlgvlcyk ffsqgvswvt aekncqslda
       61 nlasvhskie hdfllsllps ssthcwfgah dgeeegqwlw tdgttfdyth wapgqpdhds
      121 edcgdlnyes sgwndgtclt kqgyvcakyl
//
LOCUS       XP_026128712             232 aa            linear   VRT 18-JUN-2025
DEFINITION  oligodendrocyte transcription factor 1-like [Carassius auratus].
ACCESSION   XP_026128712
VERSION     XP_026128712.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272927.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..232
                     /product="oligodendrocyte transcription factor 1-like"
                     /calculated_mol_wt=24758
     Region          54..141
                     /region_name="bHLH_SF"
                     /note="basic Helix Loop Helix (bHLH) domain superfamily;
                     cl00081"
                     /db_xref="CDD:469605"
     Site            order(67..68,70,75,115..116)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:381512"
     Site            order(73..74,77..78,80..81,86,116..117,120..121,124,
                     126..127,130..131)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:381512"
     CDS             1..232
                     /gene="LOC113109307"
                     /coded_by="XM_026272927.1:250..948"
                     /db_xref="GeneID:113109307"
ORIGIN      
        1 mqavsgfrck eqgegslqql mprivrvtgg sgsgagvlqg pqrsskpsre lsveeqqelr
       61 rkinsrerkr mqdlnvamda lrevmvpyss stgvggalqy pylppgappt grrlskistl
      121 vlarnyilll gsslqemrrl lgevsigmga sgtvprlllt ggwpfltgpg qlllsppeqq
      181 mgaakcpllp qgtqeeplaw gsgsmsaspv cqcgvcrtpr vvhvnlttrl pk
//
LOCUS       XP_026128713             341 aa            linear   VRT 18-JUN-2025
DEFINITION  G-protein coupled receptor 183-like [Carassius auratus].
ACCESSION   XP_026128713
VERSION     XP_026128713.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272928.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..341
                     /product="G-protein coupled receptor 183-like"
                     /calculated_mol_wt=38959
     Region          32..316
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          34..58
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410628"
     Region          67..88
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410628"
     Region          105..127
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410628"
     Region          150..166
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410628"
     Region          193..216
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:410628"
     Region          242..264
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:410628"
     Region          284..309
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:410628"
     CDS             1..341
                     /gene="LOC113109309"
                     /coded_by="XM_026272928.1:77..1102"
                     /db_xref="GeneID:113109309"
ORIGIN      
        1 mtdqtpqqtm pmndssknqt cdvfiykesa riifptfycl vfiisvagns lvlcitcqkk
       61 qkmnsttmyi inlaisdtlf tlalpgriiy yiqgfdwpfg dflcrltami fysntyasia
      121 fmtcisvdry lamlhrqrcq rlrknkvvrg icilvwvvvl letspllmkn tmeyrsghrt
      181 cmefsnfdsp rmayvllfac iigfciplgl ilccysqvsy klsktakenp vtsrsgsnsr
      241 aknmillill sfgvcfspyh iniiqyavrr lyneptcedl ktlkmslqvt vsmmnfnscl
      301 dpiiyffaik tykqrvmslf ksylsvsass rsmqensssn t
//
LOCUS       XP_026128714             341 aa            linear   VRT 18-JUN-2025
DEFINITION  G-protein coupled receptor 183-like [Carassius auratus].
ACCESSION   XP_026128714
VERSION     XP_026128714.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272929.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..341
                     /product="G-protein coupled receptor 183-like"
                     /calculated_mol_wt=38959
     Region          32..316
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          34..58
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410628"
     Region          67..88
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410628"
     Region          105..127
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410628"
     Region          150..166
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410628"
     Region          193..216
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:410628"
     Region          242..264
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:410628"
     Region          284..309
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:410628"
     CDS             1..341
                     /gene="LOC113109309"
                     /coded_by="XM_026272929.1:73..1098"
                     /db_xref="GeneID:113109309"
ORIGIN      
        1 mtdqtpqqtm pmndssknqt cdvfiykesa riifptfycl vfiisvagns lvlcitcqkk
       61 qkmnsttmyi inlaisdtlf tlalpgriiy yiqgfdwpfg dflcrltami fysntyasia
      121 fmtcisvdry lamlhrqrcq rlrknkvvrg icilvwvvvl letspllmkn tmeyrsghrt
      181 cmefsnfdsp rmayvllfac iigfciplgl ilccysqvsy klsktakenp vtsrsgsnsr
      241 aknmillill sfgvcfspyh iniiqyavrr lyneptcedl ktlkmslqvt vsmmnfnscl
      301 dpiiyffaik tykqrvmslf ksylsvsass rsmqensssn t
//
LOCUS       XP_026128715             387 aa            linear   VRT 18-JUN-2025
DEFINITION  protein mab-21-like 3 [Carassius auratus].
ACCESSION   XP_026128715
VERSION     XP_026128715.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272930.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..387
                     /product="protein mab-21-like 3"
                     /calculated_mol_wt=44973
     Region          82..273
                     /region_name="Mab-21"
                     /note="Mab-21 protein nucleotidyltransferase domain;
                     pfam03281"
                     /db_xref="CDD:460873"
     Region          280..376
                     /region_name="Mab-21_C"
                     /note="Mab-21 protein HhH/H2TH-like domain; pfam20266"
                     /db_xref="CDD:466416"
     CDS             1..387
                     /gene="LOC113109312"
                     /coded_by="XM_026272930.1:112..1275"
                     /db_xref="GeneID:113109312"
ORIGIN      
        1 mtnftdedld nylqnqvdlr hrqvsksved vqkiikdlta evsskdarfq siansgvhna
       61 slkdqpalvs kwsallrgrc aynpaiqvlt ptlflisvpl qglmgykerr trqwryytls
      121 gsrllspvre peklhqwlel esfvnpnqew hdarmiiegd ivpakvvnvf kehleasikt
      181 cgltskvsml esvgsvvrva vetseaqiev elvptvelmn ywpkrarwpr lfrrwpster
      241 arciksfgfn lmatsnyhwl lsfsraeqvl lsnidedggc rrkcyrvvrq lkedvwcpgs
      301 kpvitayhlq tllfwtceky pctrdwrdfr gcvlrlvqkl ykcvsqhylr hyfvrshnll
      361 kysntneldd vakkinnfld npgtyvh
//
LOCUS       XP_026128716             295 aa            linear   VRT 18-JUN-2025
DEFINITION  junctional adhesion molecule B-like isoform X1 [Carassius auratus].
ACCESSION   XP_026128716
VERSION     XP_026128716.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272931.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..295
                     /product="junctional adhesion molecule B-like isoform X1"
                     /calculated_mol_wt=32770
     Region          25..126
                     /region_name="IgV_1_JAM1-like"
                     /note="First Ig-like domain of Junctional adhesion
                     molecule-1 (JAM1)and similar domains; a member of the
                     V-set of IgSF domains; cd20946"
                     /db_xref="CDD:409538"
     Region          25..47
                     /region_name="FR1"
                     /note="FR1 [structural motif]"
                     /db_xref="CDD:409538"
     Region          25..28
                     /region_name="Ig strand A"
                     /note="Ig strand A [structural motif]"
                     /db_xref="CDD:409538"
     Region          32..36
                     /region_name="Ig strand A'"
                     /note="Ig strand A' [structural motif]"
                     /db_xref="CDD:409538"
     Region          39..48
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409538"
     Region          48..55
                     /region_name="CDR1"
                     /note="CDR1 [structural motif]"
                     /db_xref="CDD:409538"
     Region          55..63
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409538"
     Region          56..63
                     /region_name="FR2"
                     /note="FR2 [structural motif]"
                     /db_xref="CDD:409538"
     Region          66..79
                     /region_name="CDR2"
                     /note="CDR2 [structural motif]"
                     /db_xref="CDD:409538"
     Region          66..71
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409538"
     Region          73..75
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409538"
     Region          80..108
                     /region_name="FR3"
                     /note="FR3 [structural motif]"
                     /db_xref="CDD:409538"
     Region          82..86
                     /region_name="Ig strand D"
                     /note="Ig strand D [structural motif]"
                     /db_xref="CDD:409538"
     Region          88..92
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409538"
     Region          101..109
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409538"
     Region          109..116
                     /region_name="CDR3"
                     /note="CDR3 [structural motif]"
                     /db_xref="CDD:409538"
     Region          116..125
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409538"
     Region          117..126
                     /region_name="FR4"
                     /note="FR4 [structural motif]"
                     /db_xref="CDD:409538"
     Region          132..223
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          146..150
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          160..164
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..191
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          201..206
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          216..219
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..295
                     /gene="LOC113109314"
                     /coded_by="XM_026272931.1:63..950"
                     /db_xref="GeneID:113109314"
ORIGIN      
        1 mstaqimtfs allmllyfps sdpvtvttsk akvevhentn avlscefrte kdtnprvewk
       61 krgkdvsyvy fdgdftgsyk grasingatm tlrgvtqkds gvyhcevtar qdkiklgevt
      121 vtlnvlvpph apscevpetv mtgfsaelrc kdklsvpaat yswykdnkpl htaslpeiky
      181 tldpktgtlk fkavsksdeg qyrceasngv gapkscagrq mkitefelnm tiviaievga
      241 flvllsccva iwlccrrgcc rccrknkret kqsrtktsyn ppdprhykht qsfvl
//
LOCUS       XP_026128717             294 aa            linear   VRT 18-JUN-2025
DEFINITION  junctional adhesion molecule B-like isoform X2 [Carassius auratus].
ACCESSION   XP_026128717
VERSION     XP_026128717.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272932.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..294
                     /product="junctional adhesion molecule B-like isoform X2"
                     /calculated_mol_wt=32683
     Region          25..126
                     /region_name="IgV_1_JAM1-like"
                     /note="First Ig-like domain of Junctional adhesion
                     molecule-1 (JAM1)and similar domains; a member of the
                     V-set of IgSF domains; cd20946"
                     /db_xref="CDD:409538"
     Region          25..47
                     /region_name="FR1"
                     /note="FR1 [structural motif]"
                     /db_xref="CDD:409538"
     Region          25..28
                     /region_name="Ig strand A"
                     /note="Ig strand A [structural motif]"
                     /db_xref="CDD:409538"
     Region          32..36
                     /region_name="Ig strand A'"
                     /note="Ig strand A' [structural motif]"
                     /db_xref="CDD:409538"
     Region          39..48
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409538"
     Region          48..55
                     /region_name="CDR1"
                     /note="CDR1 [structural motif]"
                     /db_xref="CDD:409538"
     Region          55..63
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409538"
     Region          56..63
                     /region_name="FR2"
                     /note="FR2 [structural motif]"
                     /db_xref="CDD:409538"
     Region          66..79
                     /region_name="CDR2"
                     /note="CDR2 [structural motif]"
                     /db_xref="CDD:409538"
     Region          66..71
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409538"
     Region          73..75
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409538"
     Region          80..108
                     /region_name="FR3"
                     /note="FR3 [structural motif]"
                     /db_xref="CDD:409538"
     Region          82..86
                     /region_name="Ig strand D"
                     /note="Ig strand D [structural motif]"
                     /db_xref="CDD:409538"
     Region          88..92
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409538"
     Region          101..109
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409538"
     Region          109..116
                     /region_name="CDR3"
                     /note="CDR3 [structural motif]"
                     /db_xref="CDD:409538"
     Region          116..125
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409538"
     Region          117..126
                     /region_name="FR4"
                     /note="FR4 [structural motif]"
                     /db_xref="CDD:409538"
     Region          132..223
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          146..150
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          160..164
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          187..191
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          201..206
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          216..219
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..294
                     /gene="LOC113109314"
                     /coded_by="XM_026272932.1:63..947"
                     /db_xref="GeneID:113109314"
ORIGIN      
        1 mstaqimtfs allmllyfps sdpvtvttsk akvevhentn avlscefrte kdtnprvewk
       61 krgkdvsyvy fdgdftgsyk grasingatm tlrgvtqkds gvyhcevtar qdkiklgevt
      121 vtlnvlvpph apscevpetv mtgfsaelrc kdklsvpaat yswykdnkpl htaslpeiky
      181 tldpktgtlk fkavsksdeg qyrceasngv gapkscagrq mkitefelnm tiviaievga
      241 flvllsccva iwlccrrgcc rccrknkret kqrtktsynp pdprhykhtq sfvl
//
LOCUS       XP_026128719             272 aa            linear   VRT 18-JUN-2025
DEFINITION  protein-lysine methyltransferase METTL21C-like [Carassius auratus].
ACCESSION   XP_026128719
VERSION     XP_026128719.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272934.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..272
                     /product="protein-lysine methyltransferase METTL21C-like"
                     /calculated_mol_wt=30983
     Region          65..232
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     Site            order(112..118,134..135,167..169,187)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]"
                     /db_xref="CDD:100107"
     CDS             1..272
                     /gene="LOC113109317"
                     /coded_by="XM_026272934.1:561..1379"
                     /db_xref="GeneID:113109317"
ORIGIN      
        1 meiegrpgln vqkkgivkqp dpvkpppnns eeedmdckdm kkealnrrna weptvfyslg
       61 netfsftgqe iniresldsf gaviwpgava lckyleknre qvdlldkavl elgagtglvs
      121 ivasllgawv tatdlpdvls nlnfnlsrnt rgrcrytpqv aalvwgqdvr rdfpssiyny
      181 dyvfcadvvy hhnfledlmi tmqyfckpgt tllwankvrf qsdlcfienf kkvfnvtlld
      241 eipqedvriy qatartsaqm reekrenqqh dv
//
LOCUS       XP_026128720             272 aa            linear   VRT 18-JUN-2025
DEFINITION  protein-lysine methyltransferase METTL21C-like [Carassius auratus].
ACCESSION   XP_026128720
VERSION     XP_026128720.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272935.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..272
                     /product="protein-lysine methyltransferase METTL21C-like"
                     /calculated_mol_wt=30983
     Region          65..232
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     Site            order(112..118,134..135,167..169,187)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]"
                     /db_xref="CDD:100107"
     CDS             1..272
                     /gene="LOC113109317"
                     /coded_by="XM_026272935.1:392..1210"
                     /db_xref="GeneID:113109317"
ORIGIN      
        1 meiegrpgln vqkkgivkqp dpvkpppnns eeedmdckdm kkealnrrna weptvfyslg
       61 netfsftgqe iniresldsf gaviwpgava lckyleknre qvdlldkavl elgagtglvs
      121 ivasllgawv tatdlpdvls nlnfnlsrnt rgrcrytpqv aalvwgqdvr rdfpssiyny
      181 dyvfcadvvy hhnfledlmi tmqyfckpgt tllwankvrf qsdlcfienf kkvfnvtlld
      241 eipqedvriy qatartsaqm reekrenqqh dv
//
LOCUS       XP_026128721             166 aa            linear   VRT 18-JUN-2025
DEFINITION  ly6/PLAUR domain-containing protein 6B [Carassius auratus].
ACCESSION   XP_026128721
VERSION     XP_026128721.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272936.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..166
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..166
                     /product="ly6/PLAUR domain-containing protein 6B"
                     /calculated_mol_wt=18552
     Region          35..138
                     /region_name="TFP"
                     /note="three-fingered protein (TFP) fold found in Ly6/uPAR
                     (LU) and snake toxin superfamily; cl45932"
                     /db_xref="CDD:480272"
     CDS             1..166
                     /gene="LOC113109320"
                     /coded_by="XM_026272936.1:410..910"
                     /db_xref="GeneID:113109320"
ORIGIN      
        1 maadlalvtv lvqllvdlvt gdsidfynim paveatpypk sfkcftceqa ldnyscnrwa
       61 edvwcpqntq fcmtihhfsh hgktklvtkr cavreecqla gcrhhknthh ecisccegmv
      121 cnvelptnhs navftqrqtq ssaaptfriw dcvtllvpvl lgllpl
//
LOCUS       XP_026128722             166 aa            linear   VRT 18-JUN-2025
DEFINITION  ly6/PLAUR domain-containing protein 6B [Carassius auratus].
ACCESSION   XP_026128722
VERSION     XP_026128722.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272937.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..166
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..166
                     /product="ly6/PLAUR domain-containing protein 6B"
                     /calculated_mol_wt=18552
     Region          35..138
                     /region_name="TFP"
                     /note="three-fingered protein (TFP) fold found in Ly6/uPAR
                     (LU) and snake toxin superfamily; cl45932"
                     /db_xref="CDD:480272"
     CDS             1..166
                     /gene="LOC113109320"
                     /coded_by="XM_026272937.1:398..898"
                     /db_xref="GeneID:113109320"
ORIGIN      
        1 maadlalvtv lvqllvdlvt gdsidfynim paveatpypk sfkcftceqa ldnyscnrwa
       61 edvwcpqntq fcmtihhfsh hgktklvtkr cavreecqla gcrhhknthh ecisccegmv
      121 cnvelptnhs navftqrqtq ssaaptfriw dcvtllvpvl lgllpl
//
LOCUS       XP_026128724             135 aa            linear   VRT 18-JUN-2025
DEFINITION  palmitoyltransferase AKR1-like [Carassius auratus].
ACCESSION   XP_026128724
VERSION     XP_026128724.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272939.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..135
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..135
                     /product="palmitoyltransferase AKR1-like"
                     /calculated_mol_wt=14958
     Region          <15..>114
                     /region_name="ANKYR"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     COG0666"
                     /db_xref="CDD:440430"
     Region          42..73
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     CDS             1..135
                     /gene="LOC113109321"
                     /coded_by="XM_026272939.1:115..522"
                     /db_xref="GeneID:113109321"
ORIGIN      
        1 mskhersrfv eqllkdelea valgleqgvy vwevidlphd sqgstplita crmgltrvmh
       61 fllkggadat lcnnsnqtal hvsqpalqge lltamirdvp hqrqlslaaw rgdlcclqdl
      121 mvsssdfnfh lhfdc
//
LOCUS       XP_026128725             289 aa            linear   VRT 18-JUN-2025
DEFINITION  transmembrane protein 163 [Carassius auratus].
ACCESSION   XP_026128725
VERSION     XP_026128725.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272940.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..289
                     /product="transmembrane protein 163"
                     /calculated_mol_wt=31515
     Region          88..>277
                     /region_name="FieF"
                     /note="Divalent metal cation (Fe/Co/Zn/Cd) efflux pump
                     [Inorganic ion transport and metabolism]; COG0053"
                     /db_xref="CDD:439823"
     CDS             1..289
                     /gene="LOC113109322"
                     /coded_by="XM_026272940.1:102..971"
                     /db_xref="GeneID:113109322"
ORIGIN      
        1 mqtnmtdstt sdpcpvpnpt ivdpsavrng qcaaaqdpnl pkrgsqddpf nmdrdqemki
       61 tdsvegqgll essmrlkphe aqsyrkkalw vswisivvtl ilavagftas fmrhsasafg
      121 fafdasldvl ssiivlwrys naaavhsahr eyiacvilgv ifilssmcil gkaihdlatk
      181 llpevgdflf svsivsglmc vilavakfml griltsrali tdgfnsmvgg imgfsilisa
      241 evfkhhptiw yldgttgvli gliilaygvk llidmvprvr qtrnyerfe
//
LOCUS       XP_026128726             150 aa            linear   VRT 18-JUN-2025
DEFINITION  ladderlectin-like [Carassius auratus].
ACCESSION   XP_026128726
VERSION     XP_026128726.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272941.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..150
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..150
                     /product="ladderlectin-like"
                     /calculated_mol_wt=16710
     Region          35..148
                     /region_name="CLECT"
                     /note="C-type lectin (CTL)/C-type lectin-like (CTLD)
                     domain; cd00037"
                     /db_xref="CDD:153057"
     Site            order(120,124,126,132,134..137,140..142)
                     /site_type="other"
                     /note="ligand binding surface [chemical binding]"
                     /db_xref="CDD:153057"
     CDS             1..150
                     /gene="LOC113109323"
                     /coded_by="XM_026272941.1:133..585"
                     /db_xref="GeneID:113109323"
ORIGIN      
        1 mailrtllll civfsnaegn lfekcpygwk nfgvrcfkff pqtvnmitae rncqsldsnl
       61 asvhnkmene flmsllppss thswigayda iqegqwvwtd gtpydytywc sgepngggse
      121 ncvvinfisn vcwvditcat sagyfcakdl
//
LOCUS       XP_026128728             150 aa            linear   VRT 18-JUN-2025
DEFINITION  ladderlectin [Carassius auratus].
ACCESSION   XP_026128728
VERSION     XP_026128728.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272943.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..150
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..150
                     /product="ladderlectin"
                     /calculated_mol_wt=16867
     Region          25..146
                     /region_name="CLECT"
                     /note="C-type lectin (CTL) or carbohydrate-recognition
                     domain (CRD); smart00034"
                     /db_xref="CDD:214480"
     Site            order(120,124,126,132,134..137,140..142)
                     /site_type="other"
                     /note="ligand binding surface [chemical binding]"
                     /db_xref="CDD:153057"
     CDS             1..150
                     /gene="LOC113109324"
                     /coded_by="XM_026272943.1:63..515"
                     /db_xref="GeneID:113109324"
ORIGIN      
        1 meilrtllfl civfsnaegn laekcpygwk nfgvrcfkff pqtvnmitae rncqsldsnl
       61 asvqnkmend flmsllppss tnfwigayda iqegqwlwtd gtpydytywc sgepsggvse
      121 ncvvinwrsn vcwvdiscat sasyfcakdl
//
LOCUS       XP_026128729             586 aa            linear   VRT 18-JUN-2025
DEFINITION  peroxisomal N(1)-acetyl-spermine/spermidine oxidase-like [Carassius
            auratus].
ACCESSION   XP_026128729
VERSION     XP_026128729.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272944.1
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 6% of CDS bases
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..586
                     /product="peroxisomal N(1)-acetyl-spermine/spermidine
                     oxidase-like"
                     /calculated_mol_wt=65004
     Region          44..>142
                     /region_name="PLN02612"
                     /note="phytoene desaturase"
                     /db_xref="CDD:215330"
     Region          103..584
                     /region_name="PLN02568"
                     /note="polyamine oxidase"
                     /db_xref="CDD:215308"
     CDS             1..586
                     /gene="LOC113109327"
                     /coded_by="XM_026272944.1:1..1761"
                     /db_xref="GeneID:113109327"
ORIGIN      
        1 mqergndfav igaadppvrp lfifcyvigs nttsifkvqt arvhkgasfr aqwitlsals
       61 pvqvfvrell fvltntflnf qlslskqlne aakmsscsgp edakvvivgs gfaglaaaat
      121 lvkggfenvl vleakerigg rvhtikpfte niievganwi hgqkgnplyk iakeenllse
      181 gtsskksrsv tsedyffked gkqvstklvd qvcsyfsklt dkasddelep rhrelsrgay
      241 lddafgespl aekenahqvf ewckrnectd eacsslyevs astisnytal kgeffntlgp
      301 ggyraildvl lkdlpsgtiq csapvksirw dlvkkghced qrypvqlvce ngqsfeadhv
      361 ivtvslgvlk dkastmfepp lpptklaaie nldfgivdki flffekrfwp ddcagvqllw
      421 kegpedkdvy eslsegeawk ktwfkkitgf dtvarhptal cgwitgreal ymeklpdsei
      481 rdncvrllrs ftgwsvpevs kmlisrwgsd shvrgsytfi pdgvdgvkaq kalasplppk
      541 deskgrkhlq vlfageatne nfyttthgay ltgvreaerl inyyad
//
LOCUS       XP_026128731             233 aa            linear   VRT 18-JUN-2025
DEFINITION  rab-like protein 3 [Carassius auratus].
ACCESSION   XP_026128731
VERSION     XP_026128731.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272946.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..233
                     /product="rab-like protein 3"
                     /calculated_mol_wt=25933
     Region          7..210
                     /region_name="RabL3"
                     /note="Rab GTPase-like family 3 (Rab-like3); cd04102"
                     /db_xref="CDD:206689"
     Site            13..20
                     /site_type="other"
                     /note="G1 box"
                     /db_xref="CDD:206689"
     Site            order(15..21,37..38,69,147..148,150,182)
                     /site_type="other"
                     /note="GTP/Mg2+ binding site [chemical binding]"
                     /db_xref="CDD:206689"
     Site            order(37..39,42..45)
                     /site_type="other"
                     /note="Switch I region"
                     /db_xref="CDD:206689"
     Site            38
                     /site_type="other"
                     /note="G2 box"
                     /db_xref="CDD:206689"
     Site            order(39,42..43,63,65,89)
                     /site_type="active"
                     /note="putative effector interaction site [active]"
                     /db_xref="CDD:206689"
     Site            order(39,42,65..66)
                     /site_type="other"
                     /note="putative GDI interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:206689"
     Site            order(42..47,61)
                     /site_type="other"
                     /note="putative GEF interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:206689"
     Site            66..69
                     /site_type="other"
                     /note="G3 box"
                     /db_xref="CDD:206689"
     Site            69
                     /site_type="other"
                     /note="Switch II region"
                     /db_xref="CDD:206689"
     Site            147..150
                     /site_type="other"
                     /note="G4 box"
                     /db_xref="CDD:206689"
     Site            182..184
                     /site_type="other"
                     /note="G5 box"
                     /db_xref="CDD:206689"
     CDS             1..233
                     /gene="LOC113109328"
                     /coded_by="XM_026272946.1:54..755"
                     /db_xref="GeneID:113109328"
ORIGIN      
        1 masldrvkvl vlgdsgvgks slvhllcqnq vlgnpswtvg csvdvrvhdy kegtpeektc
       61 yielwdvggs vdsassvkst ravfynsvng iilvhdltnk kssqnlnpws lealskdssp
      121 tgiivsngdy dreqfaensv pllligtkfd qipenkrndv ltrtaflsed fnaeeinldc
      181 tnprylaags snavklsrff dkviekryft rdpsqmqsft drrrfnfksl hnd
//
LOCUS       XP_026128732             257 aa            linear   VRT 18-JUN-2025
DEFINITION  granzyme B-like [Carassius auratus].
ACCESSION   XP_026128732
VERSION     XP_026128732.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272947.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..257
                     /product="granzyme B-like"
                     /calculated_mol_wt=28632
     Region          22..255
                     /region_name="Tryp_SPc"
                     /note="Trypsin-like serine protease; Many of these are
                     synthesized as inactive precursor zymogens that are
                     cleaved during limited proteolysis to generate their
                     active forms. Alignment contains also inactive enzymes
                     that have substitutions of the catalytic triad...;
                     cd00190"
                     /db_xref="CDD:238113"
     Site            22
                     /site_type="active"
                     /note="cleavage site [active]"
                     /db_xref="CDD:238113"
     Site            order(62,116,211)
                     /site_type="active"
                     /db_xref="CDD:238113"
     Site            order(205,226,230)
                     /site_type="other"
                     /note="substrate binding sites [chemical binding]"
                     /db_xref="CDD:238113"
     CDS             1..257
                     /gene="LOC113109329"
                     /coded_by="XM_026272947.1:19..792"
                     /db_xref="GeneID:113109329"
ORIGIN      
        1 mvlysfllll gislaggmes giiggkeakr nsrpymasiq nnkchtcggm liredyvlta
       61 ahclnldvns dldnievvlg ahsinkvenn qqripvmeyi khplykksne qdlsydimll
      121 klknkaklnk fvkvihlpkk nrktpanvkc siagwgiksp kgneasdvmq evklkleens
      181 kckgmwqhyf npeimicsvs dgkhafckgd sgsplickti pqglasytfd gnctntvypq
      241 vytkisyflp wikkiig
//
LOCUS       XP_026128733             232 aa            linear   VRT 18-JUN-2025
DEFINITION  oligodendrocyte transcription factor 1-like [Carassius auratus].
ACCESSION   XP_026128733
VERSION     XP_026128733.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272948.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..232
                     /product="oligodendrocyte transcription factor 1-like"
                     /calculated_mol_wt=24832
     Region          54..141
                     /region_name="bHLH_SF"
                     /note="basic Helix Loop Helix (bHLH) domain superfamily;
                     cl00081"
                     /db_xref="CDD:469605"
     Site            order(67..68,70,75,115..116)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:381512"
     Site            order(73..74,77..78,80..81,86,116..117,120..121,124,
                     126..127,130..131)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:381512"
     CDS             1..232
                     /gene="LOC113109330"
                     /coded_by="XM_026272948.1:64..762"
                     /db_xref="GeneID:113109330"
ORIGIN      
        1 mqavsgfrck eqgegslqql mprmvrvtgg sgsgagvlqg pqrsskppre lsveeqqelr
       61 rkinsrerkr mqdlnvamda lrevmvpyss stgvggalqy pylppgappt grrlskistl
      121 vlarnyilll gsslqemrrl lgevsigmga sgtvprlllt ggwpfltgpg qlllsppeqq
      181 mgaakcpllp qgtqeeplaw gsgsmsvspv cqcgvcrtpr vvhvnpttrf pk
//
LOCUS       XP_026128734             273 aa            linear   VRT 18-JUN-2025
DEFINITION  oligodendrocyte transcription factor 2-like [Carassius auratus].
ACCESSION   XP_026128734
VERSION     XP_026128734.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272949.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..273
                     /product="oligodendrocyte transcription factor 2-like"
                     /calculated_mol_wt=28597
     Region          69..153
                     /region_name="bHLH_TS_OLIG2"
                     /note="basic helix-loop-helix (bHLH) domain found in
                     oligodendrocyte transcription factor 2 (Oligo2) and
                     similar proteins; cd18940"
                     /db_xref="CDD:381510"
     Site            order(84,88,90..92,94,99,119..122)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:381510"
     Site            order(97..98,101..102,104..105,123,126,130,132..133,137,
                     139..140)
                     /site_type="other"
                     /note="putative dimer interface [polypeptide binding]"
                     /db_xref="CDD:381510"
     CDS             1..273
                     /gene="LOC113109331"
                     /coded_by="XM_026272949.1:149..970"
                     /db_xref="GeneID:113109331"
ORIGIN      
        1 mdsdtsrvss rpsspegddl flsavkksvg fsgavsstqs dsppelrgtd lrglssaded
       61 alslkmlskk drkllsesel qnmrlkinsr erkrmhdlni amdglrevmp yahgpsvrkl
      121 skiatlllar nyilmlsnsl eemkrlvsei ygggsgahht gfhpsscgtl thaagaplpg
      181 hpaavshssh pvhhpllppa vstaaclsgp glsavrphhg llkapsasag algagfqhwg
      241 agipcpcsmc qvppphvsgm stvsmprlts dsk
//
LOCUS       XP_026128735             122 aa            linear   VRT 18-JUN-2025
DEFINITION  helix-loop-helix protein 2-like [Carassius auratus].
ACCESSION   XP_026128735
VERSION     XP_026128735.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272950.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..122
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..122
                     /product="helix-loop-helix protein 2-like"
                     /calculated_mol_wt=13952
     Region          50..122
                     /region_name="bHLH_SF"
                     /note="basic Helix Loop Helix (bHLH) domain superfamily;
                     cl00081"
                     /db_xref="CDD:469605"
     Site            order(73..74,76,81,101..102)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:381392"
     Site            order(79..80,83..84,86..87,91,102..103,106..107,110,
                     112..113,116..117)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:381392"
     CDS             1..122
                     /gene="LOC113109333"
                     /coded_by="XM_026272950.1:566..934"
                     /db_xref="GeneID:113109333"
ORIGIN      
        1 mmlspdqtdp dltwtqpdee clnvmkvecv ahepleaedg ktralvpaal treekrrrrr
       61 atakyrsaha trerirveaf nvafaelrkl lptlppdkkl skieilrlai cyisylnhvl
      121 dv
//
LOCUS       XP_026128736             527 aa            linear   VRT 18-JUN-2025
DEFINITION  vang-like protein 1 [Carassius auratus].
ACCESSION   XP_026128736
VERSION     XP_026128736.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272951.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..527
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..527
                     /product="vang-like protein 1"
                     /calculated_mol_wt=58834
     Region          13..527
                     /region_name="Strabismus"
                     /note="Strabismus protein; pfam06638"
                     /db_xref="CDD:461971"
     CDS             1..527
                     /gene="LOC113109334"
                     /coded_by="XM_026272951.1:298..1881"
                     /db_xref="GeneID:113109334"
ORIGIN      
        1 mdtdsihsgy shhsnrsrgs nkqserssrd rhkshsrdss srsdknvtis assaqpqqpd
       61 qssaptdaqd dnwgetttav tgtsdhslsq edlagfgket egpveklncv rflplaltlv
      121 lgllvlitpl sflvlpqlmw perlqacgta ceglflslaf kllilllagw allvrpawas
      181 lpriavfral lglltlllll sywlffgvri ldsqdenyqg ivqfavslvd allfihylav
      241 vlleirhlqp cfslcvvrst dgethhynlg qlsiqraalv ilehyykdfs vhnpalltaa
      301 ksraakhlag lkvynvdgag sdtataqsra kiaaaarqrd tshnelyyee aehdrrvrkr
      361 rarlvvavee afthvrrlqe eekkklpgde mdpreaaqai fpsmaralqk ylrttrqqhc
      421 hsmdsiqahl afcitnnmtp kaflesylma gptlqytres rqtrqwtlvs easvnsplrq
      481 gsefqlkssd fslvvtskai phlklgeeyv hpkshkfvlq lqsetsv
//
LOCUS       XP_026128738             406 aa            linear   VRT 18-JUN-2025
DEFINITION  calsequestrin-2-like [Carassius auratus].
ACCESSION   XP_026128738
VERSION     XP_026128738.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272953.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..406
                     /product="calsequestrin-2-like"
                     /calculated_mol_wt=46669
     Region          23..372
                     /region_name="Calsequestrin"
                     /note="pfam01216"
                     /db_xref="CDD:395972"
     CDS             1..406
                     /gene="LOC113109337"
                     /coded_by="XM_026272953.1:108..1328"
                     /db_xref="GeneID:113109337"
ORIGIN      
        1 mqttwillla slglstlaga ekglefpryd gkdrvldine knyrkglkky dmlclfyhap
       61 pptakelqkq lqmtelvlel aaqvleekdi gfgmvdsqkd akvakklglh eegsvyvfke
      121 drviefdgll tadtlvefll dllddpveii dnalelrafd nmeediklig ffksgdsehy
      181 lafqeaaeqf qpfikffatf eksvakeltl kmnevdfyep fmeepvtipd kphseeelva
      241 fisehrrptl rklraedmfe tweddlngih ivafaeeedp dgfefleilk evardnthnp
      301 dlsivwidpd nfpllipywe ktfkvdlfrp qigvvnvtda dsvwleipdd delpspeele
      361 nwiedvlsgt vntedddddd nddddddndd ddddddeddd ddddde
//
LOCUS       XP_026128739             364 aa            linear   VRT 18-JUN-2025
DEFINITION  tryptophan--tRNA ligase, mitochondrial-like [Carassius auratus].
ACCESSION   XP_026128739
VERSION     XP_026128739.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272954.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..364
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..364
                     /product="tryptophan--tRNA ligase, mitochondrial-like"
                     /calculated_mol_wt=40429
     Region          42..364
                     /region_name="PRK00927"
                     /note="tryptophanyl-tRNA synthetase; Reviewed"
                     /db_xref="CDD:234866"
     CDS             1..364
                     /gene="LOC113109338"
                     /coded_by="XM_026272954.1:1..1095"
                     /db_xref="GeneID:113109338"
ORIGIN      
        1 malslrfnvk svfrfvyksn shrrlctagk atgmtglpka qvfsgiqptg vphlgnylga
       61 leswvalqdk ystvmysivd lhsitqpqdp qmlrenildm aasllacgid ptrsilfqqs
      121 qvsehaelsw ilgcltsmpr lrhlpqwkmk skqknegsvg lftypvlqaa dillyksthv
      181 pvgedqiqhl elaqdlarif nnqygeffpe prallsdtrk vkslrdpssk msksdpqkla
      241 tvfltdtpdd ivlkirravt dftsevtyep esrpgvsnlv smhaavsgqs veevvrlaeg
      301 mdtgqyknvv aeaivqklqp irleiqrlka drghleslla kgtakarsfa apvmtevrkl
      361 vgfy
//
LOCUS       XP_026128740             274 aa            linear   VRT 18-JUN-2025
DEFINITION  V-set domain-containing T-cell activation inhibitor 1-like
            [Carassius auratus].
ACCESSION   XP_026128740
VERSION     XP_026128740.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272955.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..274
                     /product="V-set domain-containing T-cell activation
                     inhibitor 1-like"
                     /calculated_mol_wt=29615
     Region          39..151
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          53..57
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          72..76
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          117..121
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          131..136
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          145..148
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          <175..235
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          179..183
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          207..211
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          219..224
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..274
                     /gene="LOC113109339"
                     /coded_by="XM_026272955.1:1..825"
                     /db_xref="GeneID:113109339"
ORIGIN      
        1 maslgqiifg smiflivlis gliifilaia fsvsqgtvds rspstvgnla edvvldcrfl
       61 snsgkeqfnd vsitwlkdsv sgvvyeyknk aaqlqgqntq fknraqlfsd visvgnasll
      121 lrnvkledeg vyrcsvnapk vsgttsvnlr vaafsaptft qrqdgslfaq ahkwfpqpev
      181 swlsqsgqll nsstqflnnt agivrvasvl kdpvkeddty tcliqnslvk aiseatitan
      241 svtertyfif saastivpsl qilltvilml saiq
//
LOCUS       XP_026128741             199 aa            linear   VRT 18-JUN-2025
DEFINITION  COMM domain-containing protein 6-like [Carassius auratus].
ACCESSION   XP_026128741
VERSION     XP_026128741.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272956.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..199
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..199
                     /product="COMM domain-containing protein 6-like"
                     /calculated_mol_wt=22345
     Region          113..197
                     /region_name="Commd"
                     /note="COMM_Domain, a family of domains found at the
                     C-terminus of HCarG, the copper metabolism gene MURR1
                     product, and related proteins. Presumably all COMM_Domain
                     containing proteins are located in the nucleus and the
                     COMM domain plays a role in...; cl06336"
                     /db_xref="CDD:471425"
     CDS             1..199
                     /gene="LOC113109340"
                     /coded_by="XM_026272956.1:78..677"
                     /db_xref="GeneID:113109340"
ORIGIN      
        1 mlgldlstsv dgvvetiekl pidlfaetlq silvylqdqn ravdlietcd kfhrvginld
       61 qkavqdiikl mtyyfrlaak snlssdvlvs kltecsskws kstlpvvhql wtergallha
      121 hqevlnmasi gqlvdiqwkl gmavssdtcr slnspfisvl mkiadtsgkm syksfemtvq
      181 qfqnfyrqfk emasvletv
//
LOCUS       XP_026128743             342 aa            linear   VRT 18-JUN-2025
DEFINITION  Krueppel-like factor 5 [Carassius auratus].
ACCESSION   XP_026128743
VERSION     XP_026128743.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272958.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..342
                     /product="Krueppel-like factor 5"
                     /calculated_mol_wt=38243
     Region          <1..255
                     /region_name="KLF5_N"
                     /note="N-terminal domain of Kruppel-like factor 5;
                     cd21579"
                     /db_xref="CDD:410335"
     Region          234..>321
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          263..282
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(267,269,271,273..274,277..278,281,297,299,303..304,
                     307..308,311,325,327,329,331..332,335..336,339)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          290..312
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          318..340
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          320..340
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..342
                     /gene="LOC113109342"
                     /coded_by="XM_026272958.1:296..1324"
                     /db_xref="GeneID:113109342"
ORIGIN      
        1 mdgwmppqfh tlsdhkkfcq dssltmdqgt pysinmnvfl pdvtylrtgm crpvrsaapq
       61 ikteplhssf nysschgsva pavthpeytn lyspatemgs nvyvkhetps hefpdvplfq
      121 llnselepng vhpctdshna tcppmptyng ihthpgqiae rphcnmsnsg yslptqfgqy
      181 lqkraaylpp sppnsepgsp drrkeliqnl spppsyaasm askmagltpg palsgqtqav
      241 paqynrrnnp dlekrrihhc dvpgckkvyt ksshlkahlr thtgekpykc swegcdwrfa
      301 rsdeltrhfr khtgakpfqc avcsrcfsrs dhlalhmkrh qn
//
LOCUS       XP_026128744             219 aa            linear   VRT 18-JUN-2025
DEFINITION  potassium/sodium hyperpolarization-activated cyclic
            nucleotide-gated channel 1 [Carassius auratus].
ACCESSION   XP_026128744
VERSION     XP_026128744.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272959.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..219
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..219
                     /product="potassium/sodium hyperpolarization-activated
                     cyclic nucleotide-gated channel 1"
                     /calculated_mol_wt=25347
     Region          100..207
                     /region_name="CAP_ED"
                     /note="effector domain of the CAP family of transcription
                     factors; members include CAP (or cAMP receptor protein
                     (CRP)), which binds cAMP, FNR (fumarate and nitrate
                     reduction), which uses an iron-sulfur cluster to sense
                     oxygen) and CooA, a heme containing CO...; cd00038"
                     /db_xref="CDD:237999"
     Site            order(163..164,173..175)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:237999"
     Site            order(195..197,201..203)
                     /site_type="other"
                     /note="flexible hinge region"
                     /db_xref="CDD:237999"
     CDS             1..219
                     /gene="LOC113109343"
                     /coded_by="XM_026272959.1:1260..1919"
                     /db_xref="GeneID:113109343"
ORIGIN      
        1 mtsivsgaim ytvmvantaa mmtdvditar ayknkmnhme dymtfmklpk alrvrinnff
       61 qaryagkwyd ekdvlkwvss slreeilmsm csahvrkvpf frncdinfin aillelqyev
      121 yqegdiiirq nipgdrmffi ehgqvleene ffqreicdgd cfgesclltk gmclatvqal
      181 ticqlfslsv dsfhsvlkdy pdirrdletf qqdkdillc
//
LOCUS       XP_026128745             183 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin B-like [Carassius auratus].
ACCESSION   XP_026128745
VERSION     XP_026128745.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272960.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..183
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..183
                     /product="gamma-crystallin B-like"
                     /calculated_mol_wt=21720
     Region          12..91
                     /region_name="XTALbg"
                     /note="Beta/gamma crystallins; smart00247"
                     /db_xref="CDD:214583"
     Region          99..180
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..183
                     /gene="LOC113109344"
                     /coded_by="XM_026272960.1:40..591"
                     /db_xref="GeneID:113109344"
ORIGIN      
        1 mklapnmdrm gkiffyedkn lqghcfecsm dcpelsshfs hcnsirvesg awvlyerpnf
       61 mgcqyiltrg eypdyqhwmg fsdsirscrm vqnhtgnfhi rlyerpefkg qimecsedwp
      121 svydrfghre vqscnvldga wvfyehpnfr ghqyllerge yhhftdwsam hptvgsirrv
      181 qel
//
LOCUS       XP_026128746             174 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M3 [Carassius auratus].
ACCESSION   XP_026128746
VERSION     XP_026128746.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272961.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..174
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..174
                     /product="gamma-crystallin M3"
                     /calculated_mol_wt=20857
     Region          3..81
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     Region          89..170
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..174
                     /gene="LOC113109345"
                     /coded_by="XM_026272961.1:46..570"
                     /db_xref="GeneID:113109345"
ORIGIN      
        1 mgkiifyedk nfqgrsyecs sdcsdmstyl srchscrves gcfvvydrpn ymgnqffmrr
       61 geyadcmrmg msdgirscrm vpqyrgpyrm riyerenfgg qmydltddcd sfmdryrmsd
      121 cqscnvmdgh wlmyeqphyr grmiyfrpge yrsfrdmgys nvrfssvrri mdlc
//
LOCUS       XP_026128747             178 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M1-like [Carassius auratus].
ACCESSION   XP_026128747
VERSION     XP_026128747.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272962.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..178
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..178
                     /product="gamma-crystallin M1-like"
                     /calculated_mol_wt=21529
     Region          3..85
                     /region_name="XTALbg"
                     /note="Beta/gamma crystallins; smart00247"
                     /db_xref="CDD:214583"
     Region          93..174
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..178
                     /gene="LOC113109346"
                     /coded_by="XM_026272962.1:35..571"
                     /db_xref="GeneID:113109346"
ORIGIN      
        1 mgkiifyedr nfqgrsydcm sdctdissyl srvgsvrves gcfmvyerns ymgnqffmrk
       61 geyhdmqrmm smgmmfdtir scrmippyrg syrmriyerd nfggqmyelm ddcdsimdry
      121 rmsdcqschv mdghwlfyeq ahyrgrmayf rpgeyrsfrd mgysnmrfms mrritdmc
//
LOCUS       XP_026128748             178 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M1-like [Carassius auratus].
ACCESSION   XP_026128748
VERSION     XP_026128748.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272963.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..178
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..178
                     /product="gamma-crystallin M1-like"
                     /calculated_mol_wt=21569
     Region          3..85
                     /region_name="XTALbg"
                     /note="Beta/gamma crystallins; smart00247"
                     /db_xref="CDD:214583"
     Region          93..174
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..178
                     /gene="LOC113109347"
                     /coded_by="XM_026272963.1:91..627"
                     /db_xref="GeneID:113109347"
ORIGIN      
        1 mgkiifyedr nfqgrsydcm sdctdissyl srvgsvrves gcfmlyerns ymgnqffmrk
       61 geyhdmqrmm smgmmfdtir scrmippyrg syrmriyerd nfggqmyelm ddcdsimdry
      121 rmsdcqschv mdghwlfyeq phyrgrmayf rpgeyrsfrd mgysnmrfms mrritdmc
//
LOCUS       XP_026128749             174 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M2-like [Carassius auratus].
ACCESSION   XP_026128749
VERSION     XP_026128749.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272964.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..174
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..174
                     /product="gamma-crystallin M2-like"
                     /calculated_mol_wt=21164
     Region          3..82
                     /region_name="XTALbg"
                     /note="Beta/gamma crystallins; smart00247"
                     /db_xref="CDD:214583"
     Region          90..171
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..174
                     /gene="LOC113109349"
                     /coded_by="XM_026272964.1:65..589"
                     /db_xref="GeneID:113109349"
ORIGIN      
        1 mgkivfyedk nfqgrsyecs ndctdlhtyf srcnsirves gcfmiyerpn ymghqyymkr
       61 geysdyqrwm gfsscirscr lipmyrgpyr lriyekadyg ghmmeftddc pcvsdrfhhr
      121 hvyscnvmng ywifyeypny rgrqyflksg eyrryrdwca tcaivgsfrr vtdy
//
LOCUS       XP_026128750             177 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M2-like [Carassius auratus].
ACCESSION   XP_026128750
VERSION     XP_026128750.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272965.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..177
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..177
                     /product="gamma-crystallin M2-like"
                     /calculated_mol_wt=20818
     Region          5..84
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     Region          92..173
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..177
                     /gene="LOC113109350"
                     /coded_by="XM_026272965.1:76..609"
                     /db_xref="GeneID:113109350"
ORIGIN      
        1 mtigkiifye drnfqgrhhe cssdcadlhp yftqcnsirv esgcfmvydh pnymgqqyfl
       61 rkgeysdcqh migfsncirs crmipmytgn yrmrlydrad mggqmielte dcpnimdrfh
      121 tsdihschvm dghwllyeqp nyrgrmyylg pgeyrkysdw ggtaprigsl rriasfn
//
LOCUS       XP_026128751             175 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin S-1-like [Carassius auratus].
ACCESSION   XP_026128751
VERSION     XP_026128751.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272966.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..175
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..175
                     /product="gamma-crystallin S-1-like"
                     /calculated_mol_wt=20076
     Region          3..82
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     Region          92..172
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..175
                     /gene="LOC113109351"
                     /coded_by="XM_026272966.1:10..537"
                     /db_xref="GeneID:113109351"
ORIGIN      
        1 mgkiifyenk nfeghqyecs gdcadmlcyl gccnsiives gcfmiyeqph ykgqpflvrk
       61 geypnfeswl gkndcvcscr eipmtqgssh evklfermey ggqmmalved cpnvmnmfqt
      121 nhifsckvig gnwlffeqsn ykgrmylirp geytrftewg gsnacvgsik rinen
//
LOCUS       XP_026128752             175 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin S-1-like [Carassius auratus].
ACCESSION   XP_026128752
VERSION     XP_026128752.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272967.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..175
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..175
                     /product="gamma-crystallin S-1-like"
                     /calculated_mol_wt=20076
     Region          3..82
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     Region          92..172
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..175
                     /gene="LOC113109351"
                     /coded_by="XM_026272967.1:10..537"
                     /db_xref="GeneID:113109351"
ORIGIN      
        1 mgkiifyenk nfeghqyecs gdcadmlcyl gccnsiives gcfmiyeqph ykgqpflvrk
       61 geypnfeswl gkndcvcscr eipmtqgssh evklfermey ggqmmalved cpnvmnmfqt
      121 nhifsckvig gnwlffeqsn ykgrmylirp geytrftewg gsnacvgsik rinen
//
LOCUS       XP_026128754             174 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M2-like [Carassius auratus].
ACCESSION   XP_026128754
VERSION     XP_026128754.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272969.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..174
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..174
                     /product="gamma-crystallin M2-like"
                     /calculated_mol_wt=20950
     Region          3..82
                     /region_name="XTALbg"
                     /note="Beta/gamma crystallins; smart00247"
                     /db_xref="CDD:214583"
     Region          90..171
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..174
                     /gene="LOC113109352"
                     /coded_by="XM_026272969.1:36..560"
                     /db_xref="GeneID:113109352"
ORIGIN      
        1 mgkiifyedr nfggryhecm sdcadlhsyf nrchsirves gcfmvydrtn fmgrqyflrr
       61 geypdymrtm gmndcvrscr mipehrgpfr mklyerqdmg grmmeleddc pnlmdrfnms
      121 dfhschvmdg hwlvyeqpny tgrhfylrpg eyrkysdwgg mssrmgsirr imdl
//
LOCUS       XP_026128755             175 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M2-like [Carassius auratus].
ACCESSION   XP_026128755
VERSION     XP_026128755.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272970.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..175
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..175
                     /product="gamma-crystallin M2-like"
                     /calculated_mol_wt=21026
     Region          3..80
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     Region          91..172
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..175
                     /gene="LOC113109353"
                     /coded_by="XM_026272970.1:6..533"
                     /db_xref="GeneID:113109353"
ORIGIN      
        1 mskiifyeer nfqgrsyecd tdcpdmhthf nrcnsikves gcwvlyerpn ysgfqyvltr
       61 geypeyhrwm gyndtirscr tfsyksdgsy ririydrpdf qgqmmefsdd cesihesfqc
      121 rsvhscnvme gywtfyehps yrgrqyfmpp geyrkfsdwg avcatigsfr ritdf
//
LOCUS       XP_026128756             286 aa            linear   VRT 18-JUN-2025
DEFINITION  BTB/POZ domain-containing protein KCTD12-like [Carassius auratus].
ACCESSION   XP_026128756
VERSION     XP_026128756.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272971.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..286
                     /product="BTB/POZ domain-containing protein KCTD12-like"
                     /calculated_mol_wt=32254
     Region          20..119
                     /region_name="BTB_POZ"
                     /note="BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ
                     (poxvirus and zinc finger) domain superfamily; cl38908"
                     /db_xref="CDD:453885"
     Region          168..286
                     /region_name="H1_KCTD12"
                     /note="H1 domain found in potassium channel
                     tetramerization domain-containing protein 12; cd22217"
                     /db_xref="CDD:409028"
     Site            order(170..171,173,177,180,189,191..193,199,201..202,219,
                     228,230..231,238,240..241,243..244,247,253,255..262,275,
                     277,280..281,283)
                     /site_type="other"
                     /note="pentamer interface [polypeptide binding]"
                     /db_xref="CDD:409028"
     Site            order(194,216,218..219,222..225,231,233,238,274)
                     /site_type="other"
                     /note="G protein beta subunit interface [polypeptide
                     binding]"
                     /db_xref="CDD:409028"
     CDS             1..286
                     /gene="LOC113109354"
                     /coded_by="XM_026272971.1:1..861"
                     /db_xref="GeneID:113109354"
ORIGIN      
        1 maladpecgi sngadsvspf sdiielnvgg qvyvtrhttl iavpdsllwd mfsrktptel
       61 ardskgrffl drdgflfryi ldylrdlnlv lpdyfpeksr lqreaeffql rdlskllspn
      121 mskdnsitde icqsdseeps appllgpdas rtvsvavtth spsleskksg yitvgyrgsy
      181 tigrdiqtda kfrrvaritv cgktslakev fgdtlnesrd pdrpperyts ryylkynfle
      241 qafdklsefg fhmvacsstg tcayssndpn edktwtsyte yvfcre
//
LOCUS       XP_026128757             475 aa            linear   VRT 18-JUN-2025
DEFINITION  cis-aconitate decarboxylase-like, partial [Carassius auratus].
ACCESSION   XP_026128757
VERSION     XP_026128757.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272972.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on the amino end.
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         <1..475
                     /product="cis-aconitate decarboxylase-like"
     Region          5..454
                     /region_name="PrpD"
                     /note="2-methylcitrate dehydratase PrpD [Carbohydrate
                     transport and metabolism]; COG2079"
                     /db_xref="CDD:441682"
     CDS             1..475
                     /gene="LOC113109355"
                     /coded_by="XM_026272972.1:<1..1428"
                     /db_xref="GeneID:113109355"
ORIGIN      
        1 sqgvtesfga avsclstshl sdevirrskr mildtlgvgl lgtstpvfnt vlqfsqrqqa
       61 lenskvwgrp glslpphyaa fvngvavhsm dfddtwhpat hpsgavlpal lalaetlpvk
      121 psglelllaf nvgievqgrl lrfskeahni pkrfhppavv gimgsaaata kllglpsahs
      181 iaalaiacss agapmanaat qtkplhmgna arggleasql allglegntq ildlesgfga
      241 fypdyvphpl aevtpnshyr wvledqniaq krfpahlgmh wvadaaiear akfldkfpna
      301 dlsqikkitl rvpssryvnc plpqsehqar hsfqfnccta lldgevtvds fsesqinrsa
      361 lkemllkvhl enpqdnhssf ekmyceiave ttqgetfsar cntfyghwrk plshedlvrk
      421 franastvlt sdvvegiiyt vdrldtnqdc smlwsymhfn khvmhrnerr ysala
//
LOCUS       XP_026128758             383 aa            linear   VRT 18-JUN-2025
DEFINITION  atypical chemokine receptor 3-like [Carassius auratus].
ACCESSION   XP_026128758
VERSION     XP_026128758.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272973.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..383
                     /product="atypical chemokine receptor 3-like"
                     /calculated_mol_wt=42772
     Region          56..344
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          58..82
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410628"
     Region          91..112
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410628"
     Region          129..151
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410628"
     Region          174..190
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410628"
     Region          221..251
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:410628"
     Region          269..291
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:410628"
     Region          312..337
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:410628"
     CDS             1..383
                     /gene="LOC113109356"
                     /coded_by="XM_026272973.1:254..1405"
                     /db_xref="GeneID:113109356"
ORIGIN      
        1 mtelqssppn eekslsanel tefftmwqel nftddnnsqv eaqmcptsfn rsallhamct
       61 lysfifvvgl aanalvvwvn lrsgrhyhdt hlyilniava dlcavatlpv wvsslaqegh
      121 wpfgqaackl thllfsinlf asifflacms vdrylsvvhs reisqrrgrq irrlvcvvtw
      181 llalfasipd ayflqsvksq hspmtlchpi ypednplqwm vgiqlsfvvl gfvipfpvia
      241 vsyallanal asssshspsn gdqdrsvsrk viltyivvfi acwapyhavl ladslamlgv
      301 fpmvcssenv lfvalnltqc lsllhccvnp vvysfahrhy rydlmkafif kyskrtglar
      361 lmegsqgtem eyamventpt avs
//
LOCUS       XP_026128759             338 aa            linear   VRT 18-JUN-2025
DEFINITION  collagen alpha-3(VI) chain-like [Carassius auratus].
ACCESSION   XP_026128759
VERSION     XP_026128759.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272974.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..338
                     /product="collagen alpha-3(VI) chain-like"
                     /calculated_mol_wt=36682
     Region          <1..94
                     /region_name="vWFA"
                     /note="Von Willebrand factor type A (vWA) domain was
                     originally found in the blood coagulation protein von
                     Willebrand factor (vWF). Typically, the vWA domain is made
                     up of approximately 200 amino acid residues folded into a
                     classic a/b para-rossmann type of...; cl00057"
                     /db_xref="CDD:469594"
     Region          130..293
                     /region_name="vWFA"
                     /note="Von Willebrand factor type A (vWA) domain was
                     originally found in the blood coagulation protein von
                     Willebrand factor (vWF). Typically, the vWA domain is made
                     up of approximately 200 amino acid residues folded into a
                     classic a/b para-rossmann type of...; cl00057"
                     /db_xref="CDD:469594"
     Site            order(137,208,243)
                     /site_type="other"
                     /note="metal ion-dependent adhesion site (MIDAS)"
                     /db_xref="CDD:238119"
     CDS             1..338
                     /gene="LOC113109357"
                     /coded_by="XM_026272974.1:59..1075"
                     /db_xref="GeneID:113109357"
ORIGIN      
        1 mrhksgrpln tgaallfike niftqssgsr rhegvpqfly lfsggrsgdd vrtisqglre
       61 nnikvitigt snsdtlelqt msttpaysfs vpdftsinsi vqrvasvlas gdeipeqfpt
      121 pggqaldagr nivflidgsd dasdrftair dfvaslaekf dvgkekdqia vvqfsntaai
      181 sfnlsrytst sevadavrnl kpkggrpqyi gqalqfvrds iftpsvrsqq kgsvsqnlvl
      241 vtggrsrdsp rgpanalknm gvaifaigsr ltdpiemeai sskkdyafav sdfhdlknvh
      301 qilitklmgg rqkgdrevdg knkknnicka letfidvr
//
LOCUS       XP_026128760             491 aa            linear   VRT 18-JUN-2025
DEFINITION  5-hydroxytryptamine receptor 2A-like [Carassius auratus].
ACCESSION   XP_026128760
VERSION     XP_026128760.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272975.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..491
                     /product="5-hydroxytryptamine receptor 2A-like"
                     /calculated_mol_wt=54408
     Region          94..424
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          96..120
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410628"
     Region          129..151
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410628"
     Region          168..190
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410628"
     Region          213..229
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410628"
     Region          251..274
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:410628"
     Region          354..376
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:410628"
     Region          392..417
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:410628"
     CDS             1..491
                     /gene="LOC113109360"
                     /coded_by="XM_026272975.1:370..1845"
                     /db_xref="GeneID:113109360"
ORIGIN      
        1 mnlyaniskp vpksiftssn lmpfdpdtwt pspdimlgnv vrnssfgcnr swadteaslf
       61 pnvsisstss ekteplswqr cngetskeel vrknwaalli lvvviitvtg nilvimavnl
      121 erklqnatny flmslavadm llgllvmpvs mvtivygysw plpaslcpmw iyldvlfsta
      181 simhlcaisl dryvairnpi rhnrsnsrsr arakitavwt isagismpip vlglrdhtkv
      241 fkdgsclltd nsfvligsfv affvpltimv vtyfltisal qseatlcldq lvprpkwstg
      301 ftlnflpgps fspsekklfl rrslsrevga esgvvmppfg rnmvqsisne qkaskvlgvv
      361 fflfvvmwcp ffitnvlavv cepatcdadv mnsllnvfvw vgylssavnp lvytlfnkty
      421 rsafaryirc qfheekkplq lilvntippl ayqsthlplt gsigngdfsl plpnkkhhls
      481 kssknesvsc l
//
LOCUS       XP_026128762             293 aa            linear   VRT 18-JUN-2025
DEFINITION  ankyrin repeat and SOCS box protein 11 [Carassius auratus].
ACCESSION   XP_026128762
VERSION     XP_026128762.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272977.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..293
                     /product="ankyrin repeat and SOCS box protein 11"
                     /calculated_mol_wt=31619
     Region          28..249
                     /region_name="ANKYR"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     COG0666"
                     /db_xref="CDD:440430"
     Region          36..67
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          69..100
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          137..165
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Site            order(140..141,144..146,148..149,153,156,165,167,169,
                     173..174,177..179,181..182,186,189,197,199,201,205..206,
                     209..211,213..214,218,221,230)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:293786"
     Region          167..197
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          199..230
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          254..293
                     /region_name="SOCS_ASB_like"
                     /note="SOCS (suppressors of cytokine signaling) box of ASB
                     (ankyrin repeat and SOCS box) and SSB (SPRY
                     domain-containing SOCS box proteins) protein families. ASB
                     family members have a C-terminal SOCS box and an
                     N-terminal ankyrin-related sequence of a variable...;
                     cd03716"
                     /db_xref="CDD:239686"
     Site            order(254..258,264,274,280,285)
                     /site_type="other"
                     /note="putative elongin B/C interaction [polypeptide
                     binding]"
                     /db_xref="CDD:239686"
     CDS             1..293
                     /gene="LOC113109364"
                     /coded_by="XM_026272977.1:852..1733"
                     /db_xref="GeneID:113109364"
ORIGIN      
        1 mavvhaevnv wskpwdhrfq lygghvcntl madswddrtp lhdaalqgrl lplrrllsqg
       61 ysvgmatldg itplheacvg ghftcaklll ehgadanavs fdgatplfra cfsgnpalvs
      121 liliyssvhh pahlqssplh eaakrghtac velllshgvn vdtevpsigt alycacqska
      181 tecvqsllis gadvhcgrgl dtplhaatrv ggakevelll ehgadrtsrn segkkalelt
      241 sdqsikhllq ttgpcslsql srwcirrslg qkglnktkml clphllhnyl lyh
//
LOCUS       XP_026128763             300 aa            linear   VRT 18-JUN-2025
DEFINITION  cyclin-dependent kinase 5 activator 1-like [Carassius auratus].
ACCESSION   XP_026128763
VERSION     XP_026128763.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272978.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..300
                     /product="cyclin-dependent kinase 5 activator 1-like"
                     /calculated_mol_wt=33584
     Region          24..291
                     /region_name="CDK5_activator"
                     /note="Cyclin-dependent kinase 5 activator protein;
                     pfam03261"
                     /db_xref="CDD:460866"
     CDS             1..300
                     /gene="LOC113109369"
                     /coded_by="XM_026272978.1:526..1428"
                     /db_xref="GeneID:113109369"
ORIGIN      
        1 mgtvlsispi vtkgtilkdg gdgetekslk kpsvvvstlt fkrlmtascq rksakkvspn
       61 plllpassds qvehlnqens rksqqsekkt ktvplvvpip tvppnldqdr dlftpaakql
      121 vsvqkqtssq slvsprqviv qastgellrc lgeflckrcc kvreltpnev vlwfrnvdrt
      181 lllqgwqdqg fitpanlvfv yllvretvsq dvdsshelhg tfltclylay symgneisyp
      241 lkpfmvdtnq dvfwersldv idklsgkmlq inmdphffte vfqdlktegd ykkdageldr
//
LOCUS       XP_026128765             174 aa            linear   VRT 18-JUN-2025
DEFINITION  gamma-crystallin M2-like [Carassius auratus].
ACCESSION   XP_026128765
VERSION     XP_026128765.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272980.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..174
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..174
                     /product="gamma-crystallin M2-like"
                     /calculated_mol_wt=21164
     Region          3..82
                     /region_name="XTALbg"
                     /note="Beta/gamma crystallins; smart00247"
                     /db_xref="CDD:214583"
     Region          90..171
                     /region_name="Crystall"
                     /note="Beta/Gamma crystallin; pfam00030"
                     /db_xref="CDD:459639"
     CDS             1..174
                     /gene="LOC113109372"
                     /coded_by="XM_026272980.1:82..606"
                     /db_xref="GeneID:113109372"
ORIGIN      
        1 mgkivfyedk nfqgrsyecs ndctdlhtyf srcnsirves gcfmiyerpn ymghqyymkr
       61 geysdyqrwm gfsscirscr lipmyrgpyr lriyekadyg ghmmeftddc pcvsdrfhhr
      121 hvyscnvmng ywifyeypny rgrqyflksg eyrryrdwca tcaivgsfrr vtdy
//
LOCUS       XP_026128766             262 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109375 isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128766
VERSION     XP_026128766.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272981.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..262
                     /product="uncharacterized protein LOC113109375 isoform X1"
                     /calculated_mol_wt=29558
     CDS             1..262
                     /gene="LOC113109375"
                     /coded_by="XM_026272981.1:157..945"
                     /db_xref="GeneID:113109375"
ORIGIN      
        1 maavsltdpl ckpssysphf kvevcvkkpl mpvhlsseqv alemlclcsq ldlliraqvh
       61 qqfqeqlkqd tspeeskcfq kqgaeiiyqm nqclehlnep vlqleeyldv vglsalfprv
      121 evymihgspi dmlerppsda yfphigrlnq llvlsqqlde dvkhlgshky iahqlsaiyq
      181 vlnslkdilp lsiirkdiea nfkqlkkslt ieegskldpq lpadrvswvs eltqnvistv
      241 lslseelted lnpvmefvsn ls
//
LOCUS       XP_026128767             261 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109375 isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128767
VERSION     XP_026128767.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272982.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..261
                     /product="uncharacterized protein LOC113109375 isoform X2"
                     /calculated_mol_wt=29430
     CDS             1..261
                     /gene="LOC113109375"
                     /coded_by="XM_026272982.1:157..942"
                     /db_xref="GeneID:113109375"
ORIGIN      
        1 maavsltdpl ckpssysphf kvevcvkkpl mpvhlsseqv alemlclcsq ldlliraqvh
       61 qfqeqlkqdt speeskcfqk qgaeiiyqmn qclehlnepv lqleeyldvv glsalfprve
      121 vymihgspid mlerppsday fphigrlnql lvlsqqlded vkhlgshkyi ahqlsaiyqv
      181 lnslkdilpl siirkdiean fkqlkkslti eegskldpql padrvswvse ltqnvistvl
      241 slseeltedl npvmefvsnl s
//
LOCUS       XP_026128769             281 aa            linear   VRT 18-JUN-2025
DEFINITION  low choriolytic enzyme [Carassius auratus].
ACCESSION   XP_026128769
VERSION     XP_026128769.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272984.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..281
                     /product="low choriolytic enzyme"
                     /calculated_mol_wt=32102
     Region          98..279
                     /region_name="ZnMc"
                     /note="Zinc-dependent metalloprotease. This super-family
                     of metalloproteases contains two major branches, the
                     astacin-like proteases and the adamalysin/reprolysin-like
                     proteases. Both branches have wide phylogenetic
                     distribution, and contain sub-families, which...; cl00064"
                     /db_xref="CDD:469599"
     Site            order(180..181,184,190)
                     /site_type="active"
                     /db_xref="CDD:238124"
     CDS             1..281
                     /gene="hce2l2"
                     /coded_by="XM_026272984.1:267..1112"
                     /db_xref="GeneID:113109376"
ORIGIN      
        1 meytlavill fflagpclsl pgqissrsnf garrqrrtys ddieentpia meriidvndy
       61 qgvisvdgtn lregdiavss rshkncfars clwtksidgk vyiaysvsha yseeelenik
      121 kgmkliehdt cvrfvprthq rdyldiqpkt gcwsylgarg grqtislqtp ectgsgvtvh
      181 elmhalgfvh eqsradrdky vtimwsniwq drlrnfekfk tdnldtpydy gsimhfgkya
      241 fsedgeptvv pkrnwnvkig qrfgpsdldi mkinrmykcn a
//
LOCUS       XP_026128770             373 aa            linear   VRT 18-JUN-2025
DEFINITION  transmembrane protein 237A isoform X1 [Carassius auratus].
ACCESSION   XP_026128770
VERSION     XP_026128770.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272985.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..373
                     /product="transmembrane protein 237A isoform X1"
                     /calculated_mol_wt=42403
     Region          109..348
                     /region_name="TMEM237"
                     /note="Transmembrane protein 237; pfam15383"
                     /db_xref="CDD:464690"
     CDS             1..373
                     /gene="tmem237a"
                     /coded_by="XM_026272985.1:218..1339"
                     /db_xref="GeneID:113109377"
ORIGIN      
        1 mrrkqttkmp svkpkkkkik kdineveepq agpepaieme gleshretlt pepqdnpplk
       61 kkkkkkahtt daseqqdfpn gdvqephtdd eevtrkskrk rkgkmmenqs hnelgveedd
      121 iitdvhapis qrslfsaplg hshpigkvfv eknrrfqvtd hldlshdhme eymevrpmwn
      181 trdvamrvhs gfriiglfsh gflagyavwn iivvyvlage qmttlhnllq qyhslaypaq
      241 sllylllais tvsafdrvnl akasialrgf ltldpaalas flyfaalils lsqqmtsdri
      301 hlyptanetl wppgsehqil qpwivvnlvv allvglawvf vatrpdmdyt eeflmameve
      361 eyprhdekne laa
//
LOCUS       XP_026128771             365 aa            linear   VRT 18-JUN-2025
DEFINITION  transmembrane protein 237A isoform X2 [Carassius auratus].
ACCESSION   XP_026128771
VERSION     XP_026128771.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272986.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..365
                     /product="transmembrane protein 237A isoform X2"
                     /calculated_mol_wt=41372
     Region          101..340
                     /region_name="TMEM237"
                     /note="Transmembrane protein 237; pfam15383"
                     /db_xref="CDD:464690"
     CDS             1..365
                     /gene="tmem237a"
                     /coded_by="XM_026272986.1:279..1376"
                     /db_xref="GeneID:113109377"
ORIGIN      
        1 mpsvkpkkkk ikkdinevee pqagpepaie megleshret ltpepqdnpp lkkkkkkkah
       61 ttdaseqqdf pngdvqepht ddeevtrksk rkrkgkmmen qshnelgvee ddiitdvhap
      121 isqrslfsap lghshpigkv fveknrrfqv tdhldlshdh meeymevrpm wntrdvamrv
      181 hsgfriiglf shgflagyav wniivvyvla geqmttlhnl lqqyhslayp aqsllyllla
      241 istvsafdrv nlakasialr gfltldpaal asflyfaali lslsqqmtsd rihlyptane
      301 tlwppgsehq ilqpwivvnl vvallvglaw vfvatrpdmd yteeflmame veeyprhdek
      361 nelaa
//
LOCUS       XP_026128772             206 aa            linear   VRT 18-JUN-2025
DEFINITION  T-cell-specific surface glycoprotein CD28 [Carassius auratus].
ACCESSION   XP_026128772
VERSION     XP_026128772.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272987.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..206
                     /product="T-cell-specific surface glycoprotein CD28"
                     /calculated_mol_wt=22946
     Region          19..130
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          33..37
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          49..53
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          91..95
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          105..110
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          122..126
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..206
                     /gene="cd28"
                     /coded_by="XM_026272987.1:26..646"
                     /db_xref="GeneID:113109378"
ORIGIN      
        1 miitlirifi yiplglalhv sqpyrvvgke gevplrcsfs sklkpeemqv slykglhgre
       61 ricssyvnls epyftsdgtv ncrgsissgr vdmmiaglrg ndtdiyrcei eilfpppylr
      121 tlgngtivyi qetpncptas tqsqiqsqsq tsereavkyd vgplpllyai liitfcslil
      181 qmiackwras tatapmlsqk esymkf
//
LOCUS       XP_026128774             210 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109383 [Carassius auratus].
ACCESSION   XP_026128774
VERSION     XP_026128774.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272989.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..210
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..210
                     /product="uncharacterized protein LOC113109383"
                     /calculated_mol_wt=24200
     Region          41..114
                     /region_name="Ig_3"
                     /note="Immunoglobulin domain; pfam13927"
                     /db_xref="CDD:464046"
     CDS             1..210
                     /gene="LOC113109383"
                     /coded_by="XM_026272989.1:91..723"
                     /db_xref="GeneID:113109383"
ORIGIN      
        1 mkifqtrilh lnlclmitll tgpdysrsnr eqkirqhiyk tvyvgetval ncnktqyddd
       61 liwkinnsvi fsqdsnsnrt mrnlssnrih idtadprelt idqiqasdag nyscypaair
      121 wtltvtenhi rpesfkqmpl yiiiiisccg vimicmiisi ticihrrwkn skdssqreag
      181 qnfsqaparg riqtqtsqyi erynsvygqi
//
LOCUS       XP_026128777             362 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109387 [Carassius auratus].
ACCESSION   XP_026128777
VERSION     XP_026128777.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272992.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..362
                     /product="uncharacterized protein LOC113109387"
                     /calculated_mol_wt=41585
     Region          115..166
                     /region_name="HTH_Tnp_4"
                     /note="Helix-turn-helix of DDE superfamily endonuclease;
                     pfam13613"
                     /db_xref="CDD:463934"
     Region          194..350
                     /region_name="DDE_Tnp_4"
                     /note="DDE superfamily endonuclease; pfam13359"
                     /db_xref="CDD:463855"
     CDS             1..362
                     /gene="LOC113109387"
                     /coded_by="XM_026272992.1:55..1143"
                     /db_xref="GeneID:113109387"
ORIGIN      
        1 metgeyyeri stndhdysaa pqpafvdlvl eenerlreei dhvrqqmeqm slkqrfglqr
       61 ftgsdsdirf ytrfssydhl mrfwqvieps lrfmvrvtra gtaniesekq sasmslqaid
      121 elflflnyla lglkqrdlae rygvhqstvs riiltwsnfl fsvlgsqciw mtqdkikehl
      181 psefedypdt ttildctelr cqtpsspllq sevysnyksh ctlkgmigma phgavtfvss
      241 lfagsvsdkq ifvesgiltl lrpdmaimvd rgflvddcvp ckvyrpafla grpqmpkhev
      301 retqsiahlr vhierlirrl kefkffdtvi plnmfgsinq lyavacllln yqsgplvkaw
      361 ak
//
LOCUS       XP_026128778             296 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109388 [Carassius auratus].
ACCESSION   XP_026128778
VERSION     XP_026128778.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272993.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..296
                     /product="uncharacterized protein LOC113109388"
                     /calculated_mol_wt=33501
     Region          102..286
                     /region_name="PDDEXK_lambda_exonuclease-like"
                     /note="Uncharacterized nucleases similar to lambda phage
                     exonuclease; cd22343"
                     /db_xref="CDD:411747"
     Site            order(157,191,207,209)
                     /site_type="active"
                     /db_xref="CDD:411747"
     CDS             1..296
                     /gene="LOC113109388"
                     /coded_by="XM_026272993.1:16..906"
                     /db_xref="GeneID:113109388"
ORIGIN      
        1 mskesaplia tmgisgdvpl vdsafgkvqe gsllsyqlpa wsppktcphs tapprpylpl
       61 dgyclgpsec cfvlthhqqm hmtslattev mahetemgtr qqskmrewhl lrkprltssr
      121 frevchvrgq ssaaslavri lksgyqsaem krglqmepka ieeycciqev nhypcgfiih
      181 pdapwlgssp dglvydpkad pvfglvevkc pnlrsyvdca ylrvsggvlq lkqshtyywq
      241 vqgqlfisgm kwcdfvvfte ddmfiqriyr degviktmkq kvdyfyfyfy lptlla
//
LOCUS       XP_026128779             252 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC113109389 [Carassius auratus].
ACCESSION   XP_026128779
VERSION     XP_026128779.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272994.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..252
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..252
                     /product="uncharacterized protein LOC113109389"
                     /calculated_mol_wt=28778
     CDS             1..252
                     /gene="LOC113109389"
                     /coded_by="XM_026272994.1:1225..1983"
                     /db_xref="GeneID:113109389"
ORIGIN      
        1 mvekvlkalh flfhcaparr dfasatatsk fplpfcghrw lenlpavera fevwpaivky
       61 vdlvkskkvk npgtssfdsi ceaqmdplll akfhffmsvs rafqpflaky qtdvpmmpfl
      121 wedlenlirn llkrfikrda lpltpyklvr lditdqklwl spkevdigmg atavikelsg
      181 akgrvsdhgl lqfrkdcqiv lsnickkald kcplkysivh nmmcldpkkm hskpddclqk
      241 ikaliqkfvq dk
//
LOCUS       XP_026128780             354 aa            linear   VRT 18-JUN-2025
DEFINITION  pituitary-specific positive transcription factor 1 [Carassius
            auratus].
ACCESSION   XP_026128780
VERSION     XP_026128780.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272995.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..354
                     /product="pituitary-specific positive transcription factor
                     1"
                     /calculated_mol_wt=39131
     Region          187..261
                     /region_name="POU"
                     /note="Found in Pit-Oct-Unc transcription factors;
                     smart00352"
                     /db_xref="CDD:197673"
     Region          278..334
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..354
                     /gene="pou1f1"
                     /coded_by="XM_026272995.1:194..1258"
                     /db_xref="GeneID:113109392"
ORIGIN      
        1 mtcqafsttd sfttlsgdsa alpllmhhtg aadclpvtsh tanmmpsglp lvqsskrshm
       61 hlsasalgna saslhypmpp chysnqqtty gmmaaqemls asisqtrilq tcsaphanmv
      121 nganslqgal asrlykfpeh slgggscalt hslpplpqal lmdeptlgdi kqelrrkirp
      181 leeppdmdsp qirelekfan dfklrriklg ytqtnvgeal aavhgsefsq tticrfenlq
      241 lsfknacklk silakwleea eqagalfnek mgmherkrkr rttislgake alernfveks
      301 kpssqeivrm aeglhlekev vrvwfcnrrq rekrvktslh hssfmaketa acrp
//
LOCUS       XP_026128782             139 aa            linear   VRT 18-JUN-2025
DEFINITION  p53-induced death domain-containing protein 1 isoform X1 [Carassius
            auratus].
ACCESSION   XP_026128782
VERSION     XP_026128782.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272997.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..139
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..139
                     /product="p53-induced death domain-containing protein 1
                     isoform X1"
                     /calculated_mol_wt=16276
     Region          17..93
                     /region_name="Death"
                     /note="Death Domain: a protein-protein interaction domain;
                     cd01670"
                     /db_xref="CDD:260017"
     CDS             1..139
                     /gene="wu:fc50b12"
                     /coded_by="XM_026272997.1:85..504"
                     /db_xref="GeneID:113109393"
ORIGIN      
        1 mpnkaqedav inmksvqeia kqlgfewtvl afelgftrne vrqfhatske krvqaqrmle
       61 swyerswdkp nktkllqdgl eragrrdlae rlrclhwghq klsrrvelps afpfiitvhk
      121 tidnkdalsr invlnrsyn
//
LOCUS       XP_026128783             129 aa            linear   VRT 18-JUN-2025
DEFINITION  p53-induced death domain-containing protein 1 isoform X2 [Carassius
            auratus].
ACCESSION   XP_026128783
VERSION     XP_026128783.1
DBLINK      BioProject: PRJNA487739
DBSOURCE    REFSEQ: accession XM_026272998.1
KEYWORDS    RefSeq.
SOURCE      Carassius auratus (goldfish)
  ORGANISM  Carassius auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Cyprininae; Carassius.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_039251.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_003368295.1-RS_2025_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/18/2025
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..129
                     /organism="Carassius auratus"
                     /strain="Wakin"
                     /db_xref="taxon:7957"
                     /chromosome="9"
                     /tissue_type="muscle"
                     /dev_stage="juvenile"
     Protein         1..129
                     /product="p53-induced death domain-containing protein 1
                     isoform X2"
                     /calculated_mol_wt=15189
     Region          7..83
                     /region_name="Death"
                     /note="Death Domain: a protein-protein interaction domain;
                     cd01670"
                     /db_xref="CDD:260017"
     CDS             1..129
                     /gene="wu:fc50b12"
                     /coded_by="XM_026272998.1:85..474"
                     /db_xref="GeneID:113109393"
ORIGIN      
        1 mpnkaqeeia kqlgfewtvl afelgftrne vrqfhatske krvqaqrmle swyerswdkp
       61 nktkllqdgl eragrrdlae rlrclhwghq klsrrvelps afpfiitvhk tidnkdalsr
      121 invlnrsyn
//
LOCUS       NP_001124141             624 aa            linear   VRT 18-JUN-2025
DEFINITION  SKI-like proto-oncogene b [Danio rerio].
ACCESSION   NP_001124141 XP_005162830
VERSION     NP_001124141.2
DBSOURCE    REFSEQ: accession NM_001130669.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 624)
  AUTHORS   Yu,F., Luo,H.R., Cui,X.F., Wu,Y.J., Li,J.L., Feng,W.R., Tang,Y.K.,
            Su,S.Y., Xiao,J., Hou,Z.S. and Xu,P.
  TITLE     Changes in aggression and locomotor behaviors in response to zinc
            is accompanied by brain cell heterogeneity and metabolic and
            circadian dysregulation of the brain-liver axis
  JOURNAL   Ecotoxicol Environ Saf 248, 114303 (2022)
   PUBMED   36403304
REFERENCE   2  (residues 1 to 624)
  AUTHORS   Boswell,M., Boswell,W., Lu,Y., Savage,M. and Walter,R.B.
  TITLE     Deconvoluting Wavelengths Leading to Fluorescent Light Induced
            Inflammation and Cellular Stress in Zebrafish (Danio rerio)
  JOURNAL   Sci Rep 10 (1), 3321 (2020)
   PUBMED   32094353
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 624)
  AUTHORS   Akieda,Y., Ogamino,S., Furuie,H., Ishitani,S., Akiyoshi,R.,
            Nogami,J., Masuda,T., Shimizu,N., Ohkawa,Y. and Ishitani,T.
  TITLE     Cell competition corrects noisy Wnt morphogen gradients to achieve
            robust patterning in the zebrafish embryo
  JOURNAL   Nat Commun 10 (1), 4710 (2019)
   PUBMED   31624259
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 624)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 624)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000024.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_005162830.2, NP_001124141.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26395012.951031.1,
                                           SRR26395062.1649971.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505374,
                                           SAMEA3505376 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..624
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="24"
                     /map="24"
     Protein         1..624
                     /product="SKI-like proto-oncogene b"
                     /note="SKI-like oncogene b"
                     /calculated_mol_wt=70322
     CDS             1..624
                     /gene="skilb"
                     /gene_synonym="zgc:193698"
                     /coded_by="NM_001130669.2:261..2135"
                     /db_xref="GeneID:100170835"
                     /db_xref="ZFIN:ZDB-GENE-080723-40"
ORIGIN      
        1 mtttenkrpd vpkdqsllkv plkrlmrdng tdgtpikkrv maalnlsckk ipetslgkae
       61 anpdlspglk htlaqfslss qcslggpaaf tshhgqykla pplaqggiag gpllvppdss
      121 tdlsmcsleg esiscfsvgg elrlclpqll ntilrdfslq qinsvcdqly lycsrcdatq
      181 lhilkvlgil ppgtpscgli tltdaqrlcn tllhpgeepl dreqeekdge esggfwvehq
      241 clgkcqglfv pqlysspdap cvrcsqcrml fcterfvmhs hrqpdkrtch wgfdsakwac
      301 ylqlaqrhlg tadeeklqqs ledmkakfqq ekrqphvgvs spafvfdsrl laglkeepsn
      361 ddlmwqswyq ythdkpagng laqhsgcvpe keigspgtem qtdtqdeknq dahntdtktl
      421 tftgqeksvq sddgsadewq rmadspdckr svehskdnmv mellqmysaq hdklqstlyr
      481 qkqlekelqa lrqgetldrc dlhgeleavq tehaqrlgev qqeqrklksr ldqlrqqecr
      541 ckqlstethq etiyarqlse lrqrldraee dreelqdelr rerearerle rtiselkqqm
      601 resthpaqhd smdspsdthm spas
//
LOCUS       NP_001019345             948 aa            linear   VRT 18-JUN-2025
DEFINITION  protocadherin 2 gamma 1 precursor [Danio rerio].
ACCESSION   NP_001019345 XP_001340196
VERSION     NP_001019345.2
DBSOURCE    REFSEQ: accession NM_001024174.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 948)
  AUTHORS   Tan,Y.P., Li,S., Jiang,X.J., Loh,W., Foo,Y.K., Loh,C.B., Xu,Q.,
            Yuen,W.H., Jones,M., Fu,J., Venkatesh,B. and Yu,W.P.
  TITLE     Regulation of protocadherin gene expression by multiple
            neuron-restrictive silencer elements scattered in the gene cluster
  JOURNAL   Nucleic Acids Res 38 (15), 4985-4997 (2010)
   PUBMED   20385576
REFERENCE   2  (residues 1 to 948)
  AUTHORS   Wu,Q.
  TITLE     Comparative genomics and diversifying selection of the clustered
            vertebrate protocadherin genes
  JOURNAL   Genetics 169 (4), 2179-2188 (2005)
   PUBMED   15744052
REFERENCE   3  (residues 1 to 948)
  AUTHORS   Tada,M.N., Senzaki,K., Tai,Y., Morishita,H., Tanaka,Y.Z.,
            Murata,Y., Ishii,Y., Asakawa,S., Shimizu,N., Sugino,H. and Yagi,T.
  TITLE     Genomic organization and transcripts of the zebrafish Protocadherin
            genes
  JOURNAL   Gene 340 (2), 197-211 (2004)
   PUBMED   15475161
REFERENCE   4  (residues 1 to 948)
  AUTHORS   Noonan,J.P., Grimwood,J., Schmutz,J., Dickson,M. and Myers,R.M.
  TITLE     Gene conversion and the evolution of protocadherin gene cluster
            diversity
  JOURNAL   Genome Res 14 (3), 354-366 (2004)
   PUBMED   14993203
REFERENCE   5  (residues 1 to 948)
  AUTHORS   Zhang,T., Haws,P. and Wu,Q.
  TITLE     Multiple variable first exons: a mechanism for cell- and
            tissue-specific gene regulation
  JOURNAL   Genome Res 14 (1), 79-89 (2004)
   PUBMED   14672974
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000014.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001019345.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588719.11804641.1,
                                           SRR32588730.28823957.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476729, SAMEA4476738
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="14"
                     /map="14"
     Protein         1..948
                     /product="protocadherin 2 gamma 1 precursor"
                     /note="protocadherin cluster 2 gamma 1"
                     /calculated_mol_wt=100450
     sig_peptide     1..29
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=3357
     CDS             1..948
                     /gene="pcdh2g1"
                     /coded_by="NM_001024174.2:130..2976"
                     /db_xref="GeneID:554047"
                     /db_xref="ZFIN:ZDB-GENE-050610-10"
ORIGIN      
        1 mfealqrlcf aaemfvllff vlmahsaygd vsysfpeemk rgfvigniak dlgldvnrls
       61 frkarihteg nrkrycdinl ntgeltvaer idreeicgkk alcvlkqelv lenplalhhf
      121 dlsiqdindn spqfkesvik feiheiavkg srylleeayd adigmnsvqs ytlqnnelfl
      181 lnvltkehgr khgelvlnke ldreqqkevt liltavdggt pprsgtvaih vtvldandna
      241 pvfsqavykv slpenspvdt vvvtvsatda degqngevty afghvsqkll qlffldsvsg
      301 vikligpidy edesiielpv qakdgqglas ysnvfidivd andnapiiil qslnspvpes
      361 alpgtevgii nvqdrdsenn gqvrcsiqqn vpfklvpsik nyyslvttge ldrellseyn
      421 ititatdegs pplsstknih ltvadvndnp pvfqqqnyra hvqennkags sicsvsatdp
      481 dwrqngtvvy sllstdvnga pvssflsing dtgvihavrs fdyeqmksfk vlvlardngs
      541 pplssnvtvs vfisdendns pqilypspeg nsfmtemvpk aaqarslvsk viavdadsgq
      601 nawlsyhiik atdpglftig vhsgeirtqr disesdsmkq nlivsvrdng qpslsatcal
      661 yllvsdnlae vpelkdmshd essskltfyl iialvsvstf fltfiiiila vrfcrrrkpr
      721 llfdgavaip saylppnyae vegagtlrsa ynydaylttg srtsdfkfvr syndgtltad
      781 ltlrktqssv ddlegldaei tdsfqqkpps adwrftqnqr pgpsgaaatp evavgtgpwp
      841 nppteaeqlq almaaanevs eatnflapgt mdlstrygpq ftlqhvpdyr qnvyipgsta
      901 tltsnqqqpq qalpppqasa aiavaqpepp kaaqtpaskk katkkekk
//
LOCUS       NP_001108536             459 aa            linear   VRT 18-JUN-2025
DEFINITION  tumor necrosis factor receptor superfamily member EDAR precursor
            [Danio rerio].
ACCESSION   NP_001108536 XP_001336695
VERSION     NP_001108536.3
DBSOURCE    REFSEQ: accession NM_001115064.3
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 459)
  AUTHORS   Lee,Y.R., Khan,K., Armfield-Uhas,K., Srikanth,S., Thompson,N.A.,
            Pardo,M., Yu,L., Norris,J.W., Peng,Y., Gripp,K.W., Aleck,K.A.,
            Li,C., Spence,E., Choi,T.I., Kwon,S.J., Park,H.M., Yu,D., Heo,W.D.,
            Mooney,M.R., Baig,S.M., Wentzensen,I.M., Telegrafi,A., McWalter,K.,
            Moreland,T., Roadhouse,C., Ramsey,K., Lyons,M.J., Skinner,C.,
            Alexov,E., Katsanis,N., Stevenson,R.E., Choudhary,J.S., Adams,D.J.,
            Kim,C.H., Davis,E.E. and Schwartz,C.E.
  TITLE     Mutations in FAM50A suggest that Armfield XLID syndrome is a
            spliceosomopathy
  JOURNAL   Nat Commun 11 (1), 3698 (2020)
   PUBMED   32703943
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 459)
  AUTHORS   He,S., Li,L., Lv,L.Y., Cai,W.J., Dou,Y.Q., Li,J., Tang,S.L.,
            Chen,X., Zhang,Z., Xu,J., Zhang,Y.P., Yin,Z., Wuertz,S., Tao,Y.X.,
            Kuhl,H. and Liang,X.F.
  TITLE     Mandarin fish (Sinipercidae) genomes provide insights into innate
            predatory feeding
  JOURNAL   Commun Biol 3 (1), 361 (2020)
   PUBMED   32647268
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 459)
  AUTHORS   Oralova,V., Rosa,J.T., Larionova,D., Witten,P.E. and Huysseune,A.
  TITLE     Multiple epithelia are required to develop teeth deep inside the
            pharynx
  JOURNAL   Proc Natl Acad Sci U S A 117 (21), 11503-11512 (2020)
   PUBMED   32398375
REFERENCE   4  (residues 1 to 459)
  AUTHORS   Aman,A.J., Fulbright,A.N. and Parichy,D.M.
  TITLE     Wnt/beta-catenin regulates an ancient signaling network during
            zebrafish scale development
  JOURNAL   Elife 7, e37001 (2018)
   PUBMED   30014845
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 459)
  AUTHORS   Henke,K., Daane,J.M., Hawkins,M.B., Dooley,C.M.,
            Busch-Nentwich,E.M., Stemple,D.L. and Harris,M.P.
  TITLE     Genetic Screen for Postembryonic Development in the Zebrafish
            (Danio rerio): Dominant Mutations Affecting Adult Form
  JOURNAL   Genetics 207 (2), 609-623 (2017)
   PUBMED   28835471
REFERENCE   6  (residues 1 to 459)
  AUTHORS   Choi,J.S., Kim,R.O., Yoon,S. and Kim,W.K.
  TITLE     Developmental Toxicity of Zinc Oxide Nanoparticles to Zebrafish
            (Danio rerio): A Transcriptomic Analysis
  JOURNAL   PLoS One 11 (8), e0160763 (2016)
   PUBMED   27504894
  REMARK    Publication Status: Online-Only
REFERENCE   7  (residues 1 to 459)
  AUTHORS   Sadier,A., Lambert,E., Chevret,P., Decimo,D., Semon,M., Tohme,M.,
            Ruggiero,F., Ohlmann,T., Pantalacci,S. and Laudet,V.
  TITLE     Tinkering signaling pathways by gain and loss of protein isoforms:
            the case of the EDA pathway regulator EDARADD
  JOURNAL   BMC Evol Biol 15, 129 (2015)
   PUBMED   26134525
  REMARK    Publication Status: Online-Only
REFERENCE   8  (residues 1 to 459)
  AUTHORS   Aigler,S.R., Jandzik,D., Hatta,K., Uesugi,K. and Stock,D.W.
  TITLE     Selection and constraint underlie irreversibility of tooth loss in
            cypriniform fishes
  JOURNAL   Proc Natl Acad Sci U S A 111 (21), 7707-7712 (2014)
   PUBMED   24821783
REFERENCE   9  (residues 1 to 459)
  AUTHORS   Harris,M.P., Rohner,N., Schwarz,H., Perathoner,S.,
            Konstantinidis,P. and Nusslein-Volhard,C.
  TITLE     Zebrafish eda and edar mutants reveal conserved and ancestral roles
            of ectodysplasin signaling in vertebrates
  JOURNAL   PLoS Genet 4 (10), e1000206 (2008)
   PUBMED   18833299
  REMARK    GeneRIF: Eda and edar are not required for early development but
            are specific for the development of adult skeletal and dental
            structures.
            Publication Status: Online-Only
REFERENCE   10 (residues 1 to 459)
  AUTHORS   Haffter,P., Odenthal,J., Mullins,M.C., Lin,S., Farrell,M.J.,
            Vogelsang,E., Haas,F., Brand,M., van Eeden,F.J., Furutani-Seiki,M.,
            Granato,M., Hammerschmidt,M., Heisenberg,C.P., Jiang,Y.J.,
            Kane,D.A., Kelsh,R.N., Hopkins,N. and Nusslein-Volhard,C.
  TITLE     Mutations affecting pigmentation and shape of the adult zebrafish
  JOURNAL   Dev Genes Evol 206 (4), 260-276 (1996)
   PUBMED   24173565
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000009.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001108536.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588714.35892423.1,
                                           SRR32588728.21990920.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA898404, SAMN01765705
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="9"
                     /map="9"
     Protein         1..459
                     /product="tumor necrosis factor receptor superfamily
                     member EDAR precursor"
                     /note="ectodysplasin receptor; finless"
                     /calculated_mol_wt=47520
     sig_peptide     1..26
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2761
     CDS             1..459
                     /gene="edar"
                     /gene_synonym="fls"
                     /coded_by="NM_001115064.3:209..1588"
                     /db_xref="GeneID:796370"
                     /db_xref="ZFIN:ZDB-GENE-070117-2062"
ORIGIN      
        1 mghkggrtps fllhfllvss mstvsaeyss cgenefynht tsscqpcpqc qagqepymnc
       61 gygtkdddys cvscpagkfs kgkyeicrrh kdcdalyrat vltpgtsdsd aecghclpgy
      121 yiqenrpqni ygmvchscqn aprnikecmr stppasgrap svssssttif pqpekdptgq
      181 ghlataliia mstifimaia ivmiimfyil kskpsgpvcc sgqlikavea qtnmqeekke
      241 aqenvvifqe kdefdklkps spktaksend asseneqlls rsidsdeeaa qdkqgaadlc
      301 llslvhltrd ktcstntinn nnnhcsratg ihsrrkkild lytkacsvae glsptelpfd
      361 clerssrmls atystdkavv ktwrhlaesf glkrdeiggm tdgmqlfdri stagysipdl
      421 larllqierl davetlccdi lsgtqnctnp plssrcasv
//
LOCUS       NP_001428526            1545 aa            linear   VRT 18-JUN-2025
DEFINITION  protein TALPID3 isoform 1 [Danio rerio].
ACCESSION   NP_001428526 XP_073783002
VERSION     NP_001428526.1
DBSOURCE    REFSEQ: accession NM_001441597.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 1545)
  AUTHORS   Noble,A.R., Masek,M., Hofmann,C., Cuoco,A., Rusterholz,T.D.S.,
            Ozkoc,H., Greter,N.R., Phelps,I.G., Vladimirov,N., Kollmorgen,S.,
            Stoeckli,E. and Bachmann-Gagescu,R.
  TITLE     Shared and unique consequences of Joubert Syndrome gene dysfunction
            on the zebrafish central nervous system
  JOURNAL   Biol Open 13 (11) (2024)
   PUBMED   39400299
REFERENCE   2  (residues 1 to 1545)
  AUTHORS   Ojeda Naharros,I., Cristian,F.B., Zang,J., Gesemann,M.,
            Ingham,P.W., Neuhauss,S.C.F. and Bachmann-Gagescu,R.
  TITLE     The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8
            activation in zebrafish photoreceptor outer segment formation and
            maintenance
  JOURNAL   Sci Rep 8 (1), 2211 (2018)
   PUBMED   29396404
  REMARK    GeneRIF: While localization of the small GTPase Rab8a, which plays
            an important role in basal body docking, appears unaffected in
            talpid3-/- photoreceptors, overexpression of constitutively active
            Rab8a rescues outer segment formation, indicating that the role of
            Ta3 in early ciliogenesis lies upstream of Rab8a activation in
            photoreceptors.
            Erratum:[Sci Rep. 2018 Aug 17;8(1):12534. doi:
            10.1038/s41598-018-30671-8. PMID: 30120317]
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1545)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 1545)
  AUTHORS   Zhou,S., Zhao,H., Thongda,W., Zhang,D., Su,B., Yu,D., Peatman,E.
            and Li,C.
  TITLE     Galectins in channel catfish, Ictalurus punctatus: Characterization
            and expression profiling in mucosal tissues
  JOURNAL   Fish Shellfish Immunol 49, 324-335 (2016)
   PUBMED   26767746
REFERENCE   5  (residues 1 to 1545)
  AUTHORS   Ben,J., Elworthy,S., Ng,A.S., van Eeden,F. and Ingham,P.W.
  TITLE     Targeted mutation of the talpid3 gene in zebrafish reveals its
            conserved requirement for ciliogenesis and Hedgehog signalling
            across the vertebrates
  JOURNAL   Development 138 (22), 4969-4978 (2011)
   PUBMED   22028029
  REMARK    GeneRIF: Targeted mutation of the talpid3 gene in zebrafish
            demonstrates that the phenotype of such maternal and zygotic
            (MZta3) mutant zebrafish showed strong similarities to that of
            chick ta3 mutants: absence of primary and motile cilia as well as
            aberrant Hedgehog (Hh) signaling.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000017.1.
            
            On Jun 18, 2025 this sequence version replaced XP_073783002.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588731.1694074.1,
                                           SRR26395028.1379245.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505371 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1545
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     Protein         1..1545
                     /product="protein TALPID3 isoform 1"
                     /note="talpid 3; ta3; talpid3; protein TALPID3"
                     /calculated_mol_wt=166785
     CDS             1..1545
                     /gene="si:ch211-185a18.2"
                     /gene_synonym="kiaa0586"
                     /coded_by="NM_001441597.1:231..4868"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:100884142"
                     /db_xref="ZFIN:ZDB-GENE-120119-1"
ORIGIN      
        1 mfleilqvid mlasslrsda advlihstra grdeiqhknq nkvniyirrl sdsehvhsad
       61 errteippvn lptasdtagp eeplagiksn qfaglfgkts rkekskaqst imqteqlksk
      121 gedvqistfs adgrgvvsaa lrkrsqgapi grnvtvqvln qdrsqtparv qpdpafplgd
      181 pgtsasvaai taatlaatap lmkaqsemea qisrvsaelk rlqaaegsvl pgrtartdss
      241 sagraahlee qlniliqqrl qhletiqcqq iqlqnrllgs aldvvasrgn ssgvsqidsl
      301 plqisgnrsi rlsatdnpsa grpasvsmdv yrerqtgghk spletpaprk vipkpthwts
      361 ststnrppks sfknqgngrl qdqspnnrrs percalqsvg verfamatad nsqpeqsres
      421 qmpskasvtr saqedgssfv ngqneqehqg eptnvsssst tvqkasemlq dlgrlknemr
      481 sllqtadafp apnakstqss rsrhlapvat apppattpis mppepvdvia vraaalnras
      541 vlksiqppts mfedaglvlr qvrqskktle enleailrak dgevlhtqle alsknrdvre
      601 elrikktvda wintlskeiq ddlaresser ivdaavsrre agqrtraeas aaakktsvra
      661 qagntrahtr qpapavrnkp avkqeatqpv vlksqddeey larlygkaly dgqrrtlkks
      721 pylrfnsptp kskpqrpkiv etvkgvkmks sktqtsqyvg dvsamqhsvs ephfifspsd
      781 pdkqqqqpgs pvrgylipma iplgkprvdc qppvpsrvii tdkpaivtts fppitvvesk
      841 pttairkpna illevqsapk krtpqlqiqv qpgvniesal cssrqasptp vipaesilpp
      901 lsnhatedph ahedqeenif pgtnflaqad isqetngglp dspiefkglp sppaalyhgp
      961 vfppvptqst pltepilnti qqretlenrl vdwveqqvma rvitgmfphp aqadpvhqse
     1021 pensvasdiv eaagggglql fvdtgvpvds evirhyvnev lteiiasmlg qresqgtptt
     1081 pvqtqdaqke dttvptpapt pepslkdpps pvrtpdlseh lstatspekp pqesaspgpd
     1141 ripvgtpitt pipsptrvat pspptpanqs pepgslqihl wegselplee eeqpelqpap
     1201 vvisvprvdd qeesvihpss pvlskpqspp applppviqk sesssssses scsssvtvte
     1261 tetaarhise gelllnhgqm aavrvleqeg vllpnfmtsl ngslhgvqdm dydppsegqv
     1321 iraphlpahh dpvlsllarm elgpisqsqq pegwweeess gevsegqrpv ltaaeeivlt
     1381 ghslmdqqti rqsrntqisp hatltspgqv iaehtgavve dgglsvnlrs sdeqkeamvy
     1441 qvdtvsspqp essqmaqtvh rpapllvrqy eeepdfpqlr rlsddaffga dekgedtflh
     1501 tgggggrgsd vrvmsvrlps vkqdqesvsl ssvegdtdss andvf
//
LOCUS       NP_001314862             445 aa            linear   VRT 18-JUN-2025
DEFINITION  tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial [Danio
            rerio].
ACCESSION   NP_001314862 XP_001337498
VERSION     NP_001314862.2
DBSOURCE    REFSEQ: accession NM_001327933.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 445)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000017.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001314862.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GFIL01015037.1, GDQH01030385.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505371 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     Protein         1..445
                     /product="tRNA (adenine(58)-N(1))-methyltransferase,
                     mitochondrial"
                     /EC_number="2.1.1.220"
                     /note="tRNA methyltransferase 61 homolog B"
                     /calculated_mol_wt=50138
     CDS             1..445
                     /gene="trmt61b"
                     /gene_synonym="si:dkey-74h17.5"
                     /coded_by="NM_001327933.2:245..1582"
                     /db_xref="GeneID:100003205"
                     /db_xref="ZFIN:ZDB-GENE-131127-35"
ORIGIN      
        1 mtppfslvls fmprkfarvs ghnvfrvkps vcglrscstd skdtdrdvse aapapasqfs
       61 rrvlgrrrpl splervsqll pqdslspevw glrdtrttee epsspsleke reeethhhhh
      121 hhvcvpgerl mcfgetlmae frrardvefr kmfelkerqk lysnwgsvah ddmegrpags
      181 virtskgipf virrvsleef vlfmkrgpai aypkdasaml tmmdvtkgdc vlecgsgsgg
      241 mslflsravg ykgsvlsvei redhhkrsvl nyqrwlntwr rrrgqewpdn vhfhhgdiis
      301 agpllagrgl nsvaldminp hlalpvvvpy lhpgsvcavy qanitqvidl lealrcsalp
      361 lvcecitevq hrdwlvvpsl kkdgtfnkrk apyensdqde pslkteevln sqdavpfgdv
      421 qyiarphpeq vghtaflvkl rkilk
//
LOCUS       NP_001428527            1533 aa            linear   VRT 18-JUN-2025
DEFINITION  protein TALPID3 isoform 2 [Danio rerio].
ACCESSION   NP_001428527
VERSION     NP_001428527.1
DBSOURCE    REFSEQ: accession NM_001441598.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 1533)
  AUTHORS   Noble,A.R., Masek,M., Hofmann,C., Cuoco,A., Rusterholz,T.D.S.,
            Ozkoc,H., Greter,N.R., Phelps,I.G., Vladimirov,N., Kollmorgen,S.,
            Stoeckli,E. and Bachmann-Gagescu,R.
  TITLE     Shared and unique consequences of Joubert Syndrome gene dysfunction
            on the zebrafish central nervous system
  JOURNAL   Biol Open 13 (11) (2024)
   PUBMED   39400299
REFERENCE   2  (residues 1 to 1533)
  AUTHORS   Ojeda Naharros,I., Cristian,F.B., Zang,J., Gesemann,M.,
            Ingham,P.W., Neuhauss,S.C.F. and Bachmann-Gagescu,R.
  TITLE     The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8
            activation in zebrafish photoreceptor outer segment formation and
            maintenance
  JOURNAL   Sci Rep 8 (1), 2211 (2018)
   PUBMED   29396404
  REMARK    GeneRIF: While localization of the small GTPase Rab8a, which plays
            an important role in basal body docking, appears unaffected in
            talpid3-/- photoreceptors, overexpression of constitutively active
            Rab8a rescues outer segment formation, indicating that the role of
            Ta3 in early ciliogenesis lies upstream of Rab8a activation in
            photoreceptors.
            Erratum:[Sci Rep. 2018 Aug 17;8(1):12534. doi:
            10.1038/s41598-018-30671-8. PMID: 30120317]
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1533)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 1533)
  AUTHORS   Zhou,S., Zhao,H., Thongda,W., Zhang,D., Su,B., Yu,D., Peatman,E.
            and Li,C.
  TITLE     Galectins in channel catfish, Ictalurus punctatus: Characterization
            and expression profiling in mucosal tissues
  JOURNAL   Fish Shellfish Immunol 49, 324-335 (2016)
   PUBMED   26767746
REFERENCE   5  (residues 1 to 1533)
  AUTHORS   Ben,J., Elworthy,S., Ng,A.S., van Eeden,F. and Ingham,P.W.
  TITLE     Targeted mutation of the talpid3 gene in zebrafish reveals its
            conserved requirement for ciliogenesis and Hedgehog signalling
            across the vertebrates
  JOURNAL   Development 138 (22), 4969-4978 (2011)
   PUBMED   22028029
  REMARK    GeneRIF: Targeted mutation of the talpid3 gene in zebrafish
            demonstrates that the phenotype of such maternal and zygotic
            (MZta3) mutant zebrafish showed strong similarities to that of
            chick ta3 mutants: absence of primary and motile cilia as well as
            aberrant Hedgehog (Hh) signaling.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000017.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588722.49217495.1,
                                           SRR32588732.3162535.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505371 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1533
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     Protein         1..1533
                     /product="protein TALPID3 isoform 2"
                     /note="talpid 3; ta3; talpid3; protein TALPID3"
                     /calculated_mol_wt=165519
     CDS             1..1533
                     /gene="si:ch211-185a18.2"
                     /gene_synonym="kiaa0586"
                     /coded_by="NM_001441598.1:231..4832"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:100884142"
                     /db_xref="ZFIN:ZDB-GENE-120119-1"
ORIGIN      
        1 mfleilqvid mlasslragr deiqhknqnk vniyirrlsd sehvhsader rteippvnlp
       61 tasdtagpee plagiksnqf aglfgktsrk ekskaqstim qteqlkskge dvqistfsad
      121 grgvvsaalr krsqgapigr nvtvqvlnqd rsqtparvqp dpafplgdpg tsasvaaita
      181 atlaataplm kaqsemeaqi srvsaelkrl qaaegsvlpg rtartdsssa graahleeql
      241 niliqqrlqh letiqcqqiq lqnrllgsal dvvasrgnss gvsqidslpl qisgnrsirl
      301 satdnpsagr pasvsmdvyr erqtgghksp letpaprkvi pkpthwtsst stnrppkssf
      361 knqgngrlqd qspnnrrspe rcalqsvgve rfamatadns qpeqsresqm pskasvtrsa
      421 qedgssfvng qneqehqgep tnvssssttv qkasemlqdl grlknemrsl lqtadafpap
      481 nakstqssrs rhlapvatap ppattpismp pepvdviavr aaalnrasvl ksiqpptsmf
      541 edaglvlrqv rqskktleen leailrakdg evlhtqleal sknrdvreel rikktvdawi
      601 ntlskeiqdd laresseriv daavsrreag qrtraeasaa akktsvraqa gntrahtrqp
      661 apavrnkpav kqeatqpvvl ksqddeeyla rlygkalydg qrrtlkkspy lrfnsptpks
      721 kpqrpkivet vkgvkmkssk tqtsqyvgdv samqhsvsep hfifspsdpd kqqqqpgspv
      781 rgylipmaip lgkprvdcqp pvpsrviitd kpaivttsfp pitvveskpt tairkpnail
      841 levqsapkkr tpqlqiqvqp gvniesalcs srqasptpvi paesilppls nhatedphah
      901 edqeenifpg tnflaqadis qetngglpds piefkglpsp paalyhgpvf ppvptqstpl
      961 tepilntiqq retlenrlvd wveqqvmarv itgmfphpaq adpvhqsepe nsvasdivea
     1021 agggglqlfv dtgvpvdsev irhyvnevlt eiiasmlgqr esqgtpttpv qtqdaqkedt
     1081 tvptpaptpe pslkdppspv rtpdlsehls tatspekppq esaspgpdri pvgtpittpi
     1141 psptrvatps pptpanqspe pgslqihlwe gselpleeee qpelqpapvv isvprvddqe
     1201 esvihpsspv lskpqsppap plppviqkse ssssssessc sssvtvtete taarhisege
     1261 lllnhgqmaa vrvleqegvl lpnfmtslng slhgvqdmdy dppsegqvir aphlpahhdp
     1321 vlsllarmel gpisqsqqpe gwweeessge vsegqrpvlt aaeeivltgh slmdqqtirq
     1381 srntqispha tltspgqvia ehtgavvedg glsvnlrssd eqkeamvyqv dtvsspqpes
     1441 sqmaqtvhrp apllvrqyee epdfpqlrrl sddaffgade kgedtflhtg ggggrgsdvr
     1501 vmsvrlpsvk qdqesvslss vegdtdssan dvf
//
LOCUS       NP_001128157             263 aa            linear   VRT 18-JUN-2025
DEFINITION  homeobox protein Hox-C3a [Danio rerio].
ACCESSION   NP_001128157 NP_571257 XP_001923828 XP_001923829
VERSION     NP_001128157.3
DBSOURCE    REFSEQ: accession NM_001134685.3
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 263)
  AUTHORS   Maeno,A., Koita,R., Nakazawa,H., Fujii,R., Yamada,K., Oikawa,S.,
            Tani,T., Ishizaka,M., Satoh,K., Ishizu,A., Sugawara,T., Adachi,U.,
            Kikuchi,M., Iwanami,N., Matsuda,M. and Kawamura,A.
  TITLE     The Hox code responsible for the patterning of the anterior
            vertebrae in zebrafish
  JOURNAL   Development 151 (14) (2024)
   PUBMED   38940461
REFERENCE   2  (residues 1 to 263)
  AUTHORS   Adachi,U., Koita,R., Seto,A., Maeno,A., Ishizu,A., Oikawa,S.,
            Tani,T., Ishizaka,M., Yamada,K., Satoh,K., Nakazawa,H.,
            Furudate,H., Kawakami,K., Iwanami,N., Matsuda,M. and Kawamura,A.
  TITLE     Teleost Hox code defines regional identities competent for the
            formation of dorsal and anal fins
  JOURNAL   Proc Natl Acad Sci U S A 121 (25), e2403809121 (2024)
   PUBMED   38861596
REFERENCE   3  (residues 1 to 263)
  AUTHORS   Sundaramoorthi,H., Fallatah,W., Mary,J. and Jagadeeswaran,P.
  TITLE     Discovery of seven hox genes in zebrafish thrombopoiesis
  JOURNAL   Blood Cells Mol Dis 104, 102796 (2024)
   PUBMED   37717409
REFERENCE   4  (residues 1 to 263)
  AUTHORS   Yamada,K., Maeno,A., Araki,S., Kikuchi,M., Suzuki,M., Ishizaka,M.,
            Satoh,K., Akama,K., Kawabe,Y., Suzuki,K., Kobayashi,D., Hamano,N.
            and Kawamura,A.
  TITLE     An atlas of seven zebrafish hox cluster mutants provides insights
            into sub/neofunctionalization of vertebrate Hox clusters
  JOURNAL   Development 148 (11) (2021)
   PUBMED   34096572
REFERENCE   5  (residues 1 to 263)
  AUTHORS   Pillay,S., Takahashi,H., Carninci,P. and Kanhere,A.
  TITLE     Antisense RNAs during early vertebrate development are divided in
            groups with distinct features
  JOURNAL   Genome Res 31 (6), 995-1010 (2021)
   PUBMED   33795334
REFERENCE   6  (residues 1 to 263)
  AUTHORS   Kurosawa,G., Takamatsu,N., Takahashi,M., Sumitomo,M., Sanaka,E.,
            Yamada,K., Nishii,K., Matsuda,M., Asakawa,S., Ishiguro,H.,
            Miura,K., Kurosawa,Y., Shimizu,N., Kohara,Y. and Hori,H.
  TITLE     Organization and structure of hox gene loci in medaka genome and
            comparison with those of pufferfish and zebrafish genomes
  JOURNAL   Gene 370, 75-82 (2006)
   PUBMED   16472944
  REMARK    Erratum:[Gene. 2006 Jul;376(2):298-9]
REFERENCE   7  (residues 1 to 263)
  AUTHORS   Corredor-Adamez,M., Welten,M.C., Spaink,H.P., Jeffery,J.E.,
            Schoon,R.T., de Bakker,M.A., Bagowski,C.P., Meijer,A.H.,
            Verbeek,F.J. and Richardson,M.K.
  TITLE     Genomic annotation and transcriptome analysis of the zebrafish
            (Danio rerio) hox complex with description of a novel member, hox b
            13a
  JOURNAL   Evol Dev 7 (5), 362-375 (2005)
   PUBMED   16174031
REFERENCE   8  (residues 1 to 263)
  AUTHORS   Santini,S. and Bernardi,G.
  TITLE     Organization and base composition of tilapia Hox genes:
            implications for the evolution of Hox clusters in fish
  JOURNAL   Gene 346, 51-61 (2005)
   PUBMED   15716008
REFERENCE   9  (residues 1 to 263)
  AUTHORS   Prohaska,S.J. and Stadler,P.F.
  TITLE     The duplication of the Hox gene clusters in teleost fishes
  JOURNAL   Theory Biosci 123 (1), 89-110 (2004)
   PUBMED   18202881
REFERENCE   10 (residues 1 to 263)
  AUTHORS   Fritz,A., Rozowski,M., Walker,C. and Westerfield,M.
  TITLE     Identification of selected gamma-ray induced deficiencies in
            zebrafish using multiplex polymerase chain reaction
  JOURNAL   Genetics 144 (4), 1735-1745 (1996)
   PUBMED   8978059
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000023.1 and EB874486.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001128157.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC154496.1, SRR32588724.2163200.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505371, SAMEA3505372
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="23"
                     /map="23"
     Protein         1..263
                     /product="homeobox protein Hox-C3a"
                     /note="homeobox protein Zf-114; hox[zf-114]; homeobox gene
                     C-3a; homeo box C3a"
                     /calculated_mol_wt=30181
     CDS             1..263
                     /gene="hoxc3a"
                     /gene_synonym="HOX-114; zgc:110503"
                     /coded_by="NM_001134685.3:178..969"
                     /db_xref="GeneID:30421"
                     /db_xref="ZFIN:ZDB-GENE-980526-532"
ORIGIN      
        1 makqskyade ngitvwlltc slqlkhrvrk aiggghhvtt lftlvgkqlk trensstwkr
       61 haeesssend kgnvwnfqnl snvqhpysfs ddgnhsldpa nalgrkkace lstsclstmk
      121 ypwmrethel mhfssiname sgdskysnge avvrnssskr arvaftssql lelekefhfs
      181 aylcrnrrle maellkltdr qikiwfqnrr mkykkdhkek stakssytyl gtenqpliis
      241 rsttdspvpl kfqnnyetps mnw
//
LOCUS       NP_001428525             391 aa            linear   VRT 18-JUN-2025
DEFINITION  ADP-ribosylation factor GTPase-activating protein 1 isoform 1
            [Danio rerio].
ACCESSION   NP_001428525 XP_073771539
VERSION     NP_001428525.1
DBSOURCE    REFSEQ: accession NM_001441596.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 391)
  AUTHORS   Bayes,A., Collins,M.O., Reig-Viader,R., Gou,G., Goulding,D.,
            Izquierdo,A., Choudhary,J.S., Emes,R.D. and Grant,S.G.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 391)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000011.1.
            
            On Jun 18, 2025 this sequence version replaced XP_073771539.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26395062.83275.1,
                                           SRR26395013.695389.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505371,
                                           SAMEA3505374 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="11"
                     /map="11"
     Protein         1..391
                     /product="ADP-ribosylation factor GTPase-activating
                     protein 1 isoform 1"
                     /calculated_mol_wt=42951
     CDS             1..391
                     /gene="arfgap1"
                     /gene_synonym="wu:fj34h02; zgc:92804"
                     /coded_by="NM_001441596.1:220..1395"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:100149572"
                     /db_xref="ZFIN:ZDB-GENE-041114-130"
ORIGIN      
        1 masprtrrvl kevrtedenn vcfecgafnp qwvsvtygiw iclecsgkhr glgvhlsfvr
       61 svsmdkwkdl elekmkaggn rkfrmflelq ddydpnwslq ekynsraaal frdkvatlad
      121 gkewsmedss arnwtppqak sslssthrss aaagqnhths drafedwlsd dvnsyqnaga
      181 sgaqenryvg fgntpnppkk eedfinnamt siysgwsnft vgaskiasia kdntsklanq
      241 atlkaaelgp tlndnvikpt qekvkegrll demavgisgl avkvqgagak gwkdmtsffs
      301 gkpdgadegs ayeegyqsqd afgapapkrd fwetfgsnsa lsgnteapae hkpstgdgwd
      361 awdnnwetsg gaqnqnqkpk pqeeswdnsg w
//
LOCUS       NP_001410440            1058 aa            linear   VRT 18-JUN-2025
DEFINITION  si:ch211-79l17.1 [Danio rerio].
ACCESSION   NP_001410440
VERSION     NP_001410440.2
DBSOURCE    REFSEQ: accession NM_001423511.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 1058)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 1058)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000018.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001410440.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQH01016670.1, SRR26395017.476308.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505371,
                                           SAMEA3505372 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="18"
                     /map="18"
     Protein         1..1058
                     /product="si:ch211-79l17.1"
                     /calculated_mol_wt=115665
     CDS             1..1058
                     /gene="si:ch211-79l17.1"
                     /gene_synonym="kiaa0355; sb:eu498"
                     /coded_by="NM_001423511.2:738..3914"
                     /db_xref="GeneID:100535053"
                     /db_xref="ZFIN:ZDB-GENE-050419-127"
ORIGIN      
        1 myccsaqesk mdyklrfllg gskhkvqqhq qfqlpelsrt lsaplgsscs tpspmvtigs
       61 spsgchappp gtttaiadiq qgiskyldal nafcrasafl telfgsvfrd sryskaamql
      121 kdvqehvmet tsrlttaikp eigkmlmels agaanfkdqn dfslqdvevl grcfltvmqv
      181 hfqflsqalq kvqpvaqscl aealaqvqer rgnahmqnhl seleeairsw rgaaevtacl
      241 rergrdgcls giqvqqlfcs qntsipehql kelnakidna lqaykvalds lghseyalka
      301 gfhlnpksve aalqgccsda eaqqagrfht tsqpiqcelp tipvqigshl lrgvsfnesa
      361 sdnlklktha vvqlikdavd qngvsvredl pitevlnqvc psswrgackt avqllfgqag
      421 lvvvdtaqie nkeayapqic legskvviqv pstwclkedp atmsllqrsl dpektlglvd
      481 vlytavfdlq rwkerkeqtl ptiqiqlqrd tsdygspvdl ppgnstkssg glpktisklt
      541 srftkkanss nssaggsfsi pstpsrssss gggsddkagr lhsllqmssm ntadpqisng
      601 aasdeqgmnl ptdqemqdvi dflsgfnmgk sqqasplvkr rnsvastnaa dlkpppssqa
      661 hnavqtltqt lqqtqqqqqq qqqqqqqqqq qlpstpkqqp pqpnsqslpf yqhllqpigq
      721 sqqqpapvsp qqpppqsraa pskwpqgpma gmspigplpq wpapglpdls sdlyslglvs
      781 symdsmmsem lghkppqgpr nntwpnreqs eqslfgvlgd smpfdpavgs dpefaryvag
      841 vnqamqqkrq aqhvrrpsns rsnwphpdeq hrgwthpeyy segeavnsgw sanqgdsass
      901 sdetssangd slfsmfsgpd lvaavkqrrk hscgeqevct lpspplhhts ddssqdsktk
      961 twppkapwqh sshtntmpnp ssslyqmtip ssqwgdsmqm lqspvwstan dcppssgfpf
     1021 tqqqqqqqqq vsqhkilskg fktfplkpeh rpsylhqy
//
LOCUS       NP_001352668            1041 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC799740 isoform 2 [Danio rerio].
ACCESSION   NP_001352668
VERSION     NP_001352668.2
DBSOURCE    REFSEQ: accession NM_001365739.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 1041)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 1041)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000017.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001352668.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA4476739, SAMEA4476790
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1041
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     Protein         1..1041
                     /product="uncharacterized protein LOC799740 isoform 2"
                     /calculated_mol_wt=117706
     CDS             1..1041
                     /gene="si:ch73-50f9.4"
                     /coded_by="NM_001365739.2:131..3256"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:799740"
                     /db_xref="ZFIN:ZDB-GENE-131122-9"
ORIGIN      
        1 maeervkdsl sgkhsvrsgs cvsrsvslks desrkglppe fseqppssnr sveyelsdsv
       61 dkthcnrksf tdhllrifqd leskifkvlk nelerfrqil qgentqdfvk gsnenqssit
      121 ksaldltllf lremkqdeva dtlenellfi nrlksslkkt yqsvsegiaq qgdstllnni
      181 ytdlyitqga neqvntehei rqieaasrch ksleiqveck hlfeapeqdk qirtvltkgv
      241 agigksvsvq kfvvdwaegk anqdislifp lpfremnlke kekqslkdli tqlfpevkgl
      301 nltrrtrnkv lfildgldec rlplnfagne tchdvsapay ldvlltnlik gnllpsaliw
      361 itsrpaaask ipadcidrlt eirgfndaqk eeyfrkrlad qnlameiieh ikqskslhim
      421 chipvfcwis atvlqnvlke tkvkhkacak tlqespktlt qmythflrfq mqqsrqkydg
      481 kntdgvswdq nfilslgkla yqqlernnvi fyesdlkdcg idvykasvys gmctqifkqe
      541 tgiilgnlyc flhlsiqefi aalyghlyld ikkksvftgq khknkgmthl lktavdkale
      601 sdnghldlyl rfllglslqt nrqllrgllt qqdksdqske eivvyikqkl eenlsperai
      661 nllyclneln dhslmkeiqs hlrdgslssa dlspaqwsal tfvlltseee ldefdlqkfk
      721 ksdeclirls aviksskral lqccnltaqs ceslslalqs stcvlreldl snndlqdsgv
      781 klisnglksc kleilrlsgc mvtetgcgfl ssalssnpth lreldlsynh pgvsgvkllc
      841 qkledpnytl aklnvdhaga kritagprkw ishltldpnt antelslsae nreatrviek
      901 qpypdhpdrf dyhpqvlcre svcgpcywei dwsgdvgaci svsyksvssk gndefgcndq
      961 swslscyssr fsyghnnrwt dlpvkpisrr igvyvdhrae tlrfynicgn tvhlvhsvrt
     1021 tftqplyagf kiypgssvkl c
//
LOCUS       NP_001428529             232 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger protein-like [Danio rerio].
ACCESSION   NP_001428529
VERSION     NP_001428529.1
DBSOURCE    REFSEQ: accession NM_001441600.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 232)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000013.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588728.7475270.1,
                                           SRR32588714.42635576.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA708836, SAMN01765705
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="13"
                     /map="13"
     Protein         1..232
                     /product="zinc finger protein-like"
                     /calculated_mol_wt=26966
     CDS             1..232
                     /gene="si:dkeyp-2e4.7"
                     /coded_by="NM_001441600.1:126..824"
                     /db_xref="GeneID:108191950"
                     /db_xref="ZFIN:ZDB-GENE-061009-51"
ORIGIN      
        1 mkpviknees lqgdpestnn dvetlvlskt egsaalfcrr lkyrvktdet sdqsssdtdt
       61 edelpistsp tpgedfimri htgeapyvce lcgkafkrkh wlkehfyiht gvkrkrkkrl
      121 scdqcemkfe cssvlqghln khrgerpfac vqcdktyfnq hdlkqhlrdc hsekkhgcyl
      181 cgnefsrrsl lqkhmrihtg erpyscphce ktfpykysfe mhvksavcrr dk
//
LOCUS       NP_956540                307 aa            linear   VRT 18-JUN-2025
DEFINITION  dnaJ homolog subfamily C member 17 [Danio rerio].
ACCESSION   NP_956540 XP_073783139
VERSION     NP_956540.3
DBSOURCE    REFSEQ: accession NM_200246.3
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 307)
  AUTHORS   Lee,H.J., Hou,Y., Chen,Y., Dailey,Z.Z., Riddihough,A., Jang,H.S.,
            Wang,T. and Johnson,S.L.
  TITLE     Regenerating zebrafish fin epigenome is characterized by stable
            lineage-specific DNA methylation and dynamic chromatin
            accessibility
  JOURNAL   Genome Biol 21 (1), 52 (2020)
   PUBMED   32106888
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000017.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_073783139.1, NP_956540.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065618.1, GDQH01020370.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505377,
                                           SAMEA3505379 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     Protein         1..307
                     /product="dnaJ homolog subfamily C member 17"
                     /calculated_mol_wt=34990
     CDS             1..307
                     /gene="dnajc17"
                     /gene_synonym="zgc:56091"
                     /coded_by="NM_200246.3:94..1017"
                     /db_xref="GeneID:393216"
                     /db_xref="ZFIN:ZDB-GENE-040426-894"
ORIGIN      
        1 mattkellem dlyallgves tstekqikke yrqralschp dknpdnpkaa elfhqlsqal
       61 evltdaaaka aydkvraakk qaeernrnld dkrkkikldl earerraenv kaeevkitrt
      121 leeeiarlre egsrelqeqq rlireqiere rdahthtdss avqqggnnvt pklklkwkck
      181 kedesnagys heclqnlfqk ygdvlnilis skkkgsavve fasakaaela cknesgltgn
      241 plkimwlegq pvqtthsent htgfgatqsc lrterdyesv vlmrlrqaee rkrlieqmkr
      301 eeeddta
//
LOCUS       NP_001373731             213 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC100150557 [Danio rerio].
ACCESSION   NP_001373731 XP_005155447
VERSION     NP_001373731.2
DBSOURCE    REFSEQ: accession NM_001386802.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 213)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000010.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001373731.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588719.10287324.1, CA496560.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505371, SAMEA3505372
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="10"
                     /map="10"
     Protein         1..213
                     /product="uncharacterized protein LOC100150557"
                     /calculated_mol_wt=22981
     CDS             1..213
                     /gene="si:ch73-52f15.5"
                     /coded_by="NM_001386802.2:80..721"
                     /db_xref="GeneID:100150557"
                     /db_xref="ZFIN:ZDB-GENE-091204-341"
ORIGIN      
        1 mmenrvlers geikdppqlf tyyqgdinta vdehffraln katipkdlsi kakdssrtpr
       61 sdipsssssp wamswskpst hssskltplt smetpspsqg vivnpsglss ssssssssss
      121 slwpcaprqs ssafelpqil yqqpasgess assylnllqm erpaggimis pfsksdtrpe
      181 wnsgaafkdv sgsrisldsg lpvseinkdl ywy
//
LOCUS       NP_001373732             213 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC100150557 [Danio rerio].
ACCESSION   NP_001373732 XP_001923521
VERSION     NP_001373732.2
DBSOURCE    REFSEQ: accession NM_001386803.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 213)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000010.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001373732.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQQ01012749.1,
                                           SRR32588726.55267864.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505370, SAMEA3505371
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="10"
                     /map="10"
     Protein         1..213
                     /product="uncharacterized protein LOC100150557"
                     /calculated_mol_wt=22981
     CDS             1..213
                     /gene="si:ch73-52f15.5"
                     /coded_by="NM_001386803.2:84..725"
                     /db_xref="GeneID:100150557"
                     /db_xref="ZFIN:ZDB-GENE-091204-341"
ORIGIN      
        1 mmenrvlers geikdppqlf tyyqgdinta vdehffraln katipkdlsi kakdssrtpr
       61 sdipsssssp wamswskpst hssskltplt smetpspsqg vivnpsglss ssssssssss
      121 slwpcaprqs ssafelpqil yqqpasgess assylnllqm erpaggimis pfsksdtrpe
      181 wnsgaafkdv sgsrisldsg lpvseinkdl ywy
//
LOCUS       NP_001239391             381 aa            linear   VRT 18-JUN-2025
DEFINITION  trophoblast glycoprotein precursor [Danio rerio].
ACCESSION   NP_001239391 XP_002664821
VERSION     NP_001239391.2
DBSOURCE    REFSEQ: accession NM_001252462.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 381)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 381)
  AUTHORS   Kagermeier-Schenk,B., Wehner,D., Ozhan-Kizil,G., Yamamoto,H.,
            Li,J., Kirchner,K., Hoffmann,C., Stern,P., Kikuchi,A., Schambony,A.
            and Weidinger,G.
  TITLE     Waif1/5T4 inhibits Wnt/beta-catenin signaling and activates
            noncanonical Wnt pathways by modifying LRP6 subcellular
            localization
  JOURNAL   Dev Cell 21 (6), 1129-1143 (2011)
   PUBMED   22100263
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000016.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001239391.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: JN653075.1, GDQH01021039.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="16"
                     /map="16"
     Protein         1..381
                     /product="trophoblast glycoprotein precursor"
                     /note="5T4 oncofetal trophoblast glycoprotein;
                     Wnt-activated inhibitory factor 1c; waif1c; trophoblast
                     glycoprotein b"
                     /calculated_mol_wt=39440
     sig_peptide     1..36
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=4017
     CDS             1..381
                     /gene="tpbg"
                     /gene_synonym="sc:d0323; sc:d0347; tpbgb"
                     /coded_by="NM_001252462.2:443..1588"
                     /db_xref="GeneID:792712"
                     /db_xref="ZFIN:ZDB-GENE-091218-2"
ORIGIN      
        1 msnvgllrll qlqtkqrsmc nltlclllfl tsscsslstc paqclcestv vncesqnlts
       61 vpqplpenit tlnlngnril nlsnasfprp lvhlthlyvs gnqlqeldma fkklsslrll
      121 dlsdnrilqf siealhqdnk ievlnfsksl cnhsyigvla dlfrhslpkv srldlsnndl
      181 vflpediftg lselslldlr nnslvsfrnv tsqnkalkel dlrdnafkal snetlselys
      241 ipnlrvrlag npwrcdcdie yllfwlekqd fvtdrlnltc asprelkhvq lvhlehsqlp
      301 cwsdnvdeln rvlepsyvfl glvlaligvi fllvlylnrk gikrwmynir dacrdhmegy
      361 hyryeinsdp glanlspnsd v
//
LOCUS       NP_001120945             426 aa            linear   VRT 18-JUN-2025
DEFINITION  SLAIN motif family, member 1b isoform 1 [Danio rerio].
ACCESSION   NP_001120945
VERSION     NP_001120945.2
DBSOURCE    REFSEQ: accession NM_001127473.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 426)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 426)
  AUTHORS   Zhang,P., Yao,Q., Lu,L., Li,Y., Chen,P.J. and Duan,C.
  TITLE     Hypoxia-inducible factor 3 is an oxygen-dependent transcription
            activator and regulates a distinct transcriptional response to
            hypoxia
  JOURNAL   Cell Rep 6 (6), 1110-1121 (2014)
   PUBMED   24613356
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000006.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001120945.1.
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="6"
                     /map="6"
     Protein         1..426
                     /product="SLAIN motif family, member 1b isoform 1"
                     /calculated_mol_wt=46638
     CDS             1..426
                     /gene="slain1b"
                     /gene_synonym="zgc:175146"
                     /coded_by="NM_001127473.2:85..1365"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:100151758"
                     /db_xref="ZFIN:ZDB-GENE-080516-6"
ORIGIN      
        1 meaavmaele lqklqelvrk lelqneqlra raitappsra crcspedepf pyfrphsaae
       61 edeeeedvde elmlldletl spsaqseetw lyvcprappw sasplsavqw crrvldqqrp
      121 emetlrhslc qsgcsvfpqs svdsgvcvsa ldadpvplds hyklqdltdv qvmarlqees
      181 lrqdfassss sssnnhrrfq cgnhsashdd ededdeddde eyaqlpppqp rlqqrslphs
      241 htfsnirewr rsssaalqth thsqssssss adslrrsmpd lltavsltpa lnsvsirssq
      301 sfesssalmr tcipapghlq trvqsvgnfs srpqlkatay vsptiksssc ssspsgpqcv
      361 sgsvpkasaa sqipsrsglp rpasfiaags nprsklstpv rsvltppknl aplsalrdgh
      421 wrdgcy
//
LOCUS       NP_001378771             319 aa            linear   MAM 18-JUN-2025
DEFINITION  olfactory receptor family 8 subfamily K member 1C [Equus caballus].
ACCESSION   NP_001378771 XP_023509808
VERSION     NP_001378771.2
DBSOURCE    REFSEQ: accession NM_001391842.2
KEYWORDS    RefSeq.
SOURCE      Equus caballus (horse)
  ORGANISM  Equus caballus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. This
            record has been curated by NCBI staff in collaboration with Tsviya
            Olender. The reference sequence was derived from JBFNWK010000012.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001378771.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: This record was generated from genomic coordinates
            provided by Tsviya Olender (Weizmann Institute of Science).
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Equus caballus"
                     /db_xref="taxon:9796"
                     /chromosome="12"
                     /map="12"
     Protein         1..319
                     /product="olfactory receptor family 8 subfamily K member
                     1C"
                     /calculated_mol_wt=36261
     CDS             1..319
                     /gene="OR8K1C"
                     /coded_by="NM_001391842.2:1..960"
                     /db_xref="GeneID:111775915"
                     /db_xref="VGNC:VGNC:105923"
ORIGIN      
        1 mnhmenqnht avtkvteyil mgitdnpglq apllgvflii ylvtvmgnlg mvilthldsk
       61 lhtpmyfflr hlsitdlgyc tvigpkmman favhkntisy tccaiqlvff eifiitelfi
      121 lsamaydryv avckpllyvi imaekvcwgl vvtpylystf vslfltirlf nssfcgsnii
      181 syfycdslpl ismlcsdthe leliilifsg cnllsslfiv llsytfifva ilrmnsterr
      241 ykafstcssh ltvvavfygt llfiylkpks shifdidkma svfytllipm lnpliyslrn
      301 kdvkdalkrt ltnqckmfi
//
LOCUS       NP_001428521             459 aa            linear   VRT 18-JUN-2025
DEFINITION  SLAIN motif family, member 1b isoform 2 [Danio rerio].
ACCESSION   NP_001428521
VERSION     NP_001428521.1
DBSOURCE    REFSEQ: accession NM_001441592.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 459)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 459)
  AUTHORS   Zhang,P., Yao,Q., Lu,L., Li,Y., Chen,P.J. and Duan,C.
  TITLE     Hypoxia-inducible factor 3 is an oxygen-dependent transcription
            activator and regulates a distinct transcriptional response to
            hypoxia
  JOURNAL   Cell Rep 6 (6), 1110-1121 (2014)
   PUBMED   24613356
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000006.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR32588730.9195091.1,
                                    SRR32588718.28382235.1 [ECO:0000331]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="6"
                     /map="6"
     Protein         1..459
                     /product="SLAIN motif family, member 1b isoform 2"
                     /calculated_mol_wt=50026
     CDS             1..459
                     /gene="slain1b"
                     /gene_synonym="zgc:175146"
                     /coded_by="NM_001441592.1:85..1464"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:100151758"
                     /db_xref="ZFIN:ZDB-GENE-080516-6"
ORIGIN      
        1 meaavmaele lqklqelvrk lelqneqlra raitappsra crcspedepf pyfrphsaae
       61 edeeeedvde elmlldletl spsaqseetw lyvcprappw sasplsavqw crrvldqqrp
      121 emetlrhslc qsvsrwwsap aspavagvpp pyisspskpc apdragcsvf pqssvdsgvc
      181 vsaldadpvp ldshyklqdl tdvqvmarlq eeslrqdfas ssssssnnhr rfqcgnhsas
      241 hddededded ddeeyaqlpp pqprlqqrsl phshtfsnir ewrrsssaal qththsqsss
      301 sssadslrrs mpdlltavsl tpalnsvsir ssqsfesssa lmrtcipapg hlqtrvqsvg
      361 nfssrpqlka tayvsptiks sscssspsgp qcvsgsvpka saasqipsrs glprpasfia
      421 agsnprskls tpvrsvltpp knlaplsalr dghwrdgcy
//
LOCUS       NP_571352                509 aa            linear   VRT 18-JUN-2025
DEFINITION  paired box protein Pax-3a [Danio rerio].
ACCESSION   NP_571352
VERSION     NP_571352.1
DBSOURCE    REFSEQ: accession NM_131277.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 509)
  AUTHORS   Duan,W., Huang,G., Sui,Y., Wang,K., Yu,Y., Chu,X., Cao,X., Chen,L.,
            Liu,J., Eichler,E.E. and Xiong,B.
  TITLE     Deficiency of DDX3X results in neurogenesis defects and abnormal
            behaviors via dysfunction of the Notch signaling
  JOURNAL   Proc Natl Acad Sci U S A 121 (45), e2404173121 (2024)
   PUBMED   39471229
REFERENCE   2  (residues 1 to 509)
  AUTHORS   Zhou,C., Li,M., Sun,Y., Sultan,Y. and Li,X.
  TITLE     Systematic Identification of Long Noncoding RNAs during Three Key
            Organogenesis Stages in Zebrafish
  JOURNAL   Int J Mol Sci 25 (6), 3440 (2024)
   PUBMED   38542412
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 509)
  AUTHORS   Miyadai,M., Takada,H., Shiraishi,A., Kimura,T., Watakabe,I.,
            Kobayashi,H., Nagao,Y., Naruse,K., Higashijima,S.I., Shimizu,T.,
            Kelsh,R.N., Hibi,M. and Hashimoto,H.
  TITLE     A gene regulatory network combining Pax3/7, Sox10 and Mitf
            generates diverse pigment cell types in medaka and zebrafish
  JOURNAL   Development 150 (19) (2023)
   PUBMED   37823232
  REMARK    GeneRIF: A gene regulatory network combining Pax3/7, Sox10 and Mitf
            generates diverse pigment cell types in medaka and zebrafish.
REFERENCE   4  (residues 1 to 509)
  AUTHORS   Watson,C.J., Tang,W.J., Rojas,M.F., Fiedler,I.A.K., Morfin Montes
            de Oca,E., Cronrath,A.R., Callies,L.K., Swearer,A.A., Ahmed,A.R.,
            Sethuraman,V., Addish,S., Farr,G.H. 3rd, Gomez,A.E., Rai,J.,
            Monstad-Rios,A.T., Gardiner,E.M., Karasik,D., Maves,L., Busse,B.,
            Hsu,Y.H. and Kwon,R.Y.
  TITLE     wnt16 regulates spine and muscle morphogenesis through parallel
            signals from notochord and dermomyotome
  JOURNAL   PLoS Genet 18 (11), e1010496 (2022)
   PUBMED   36346812
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 509)
  AUTHORS   Kahsay,A., Rodriguez-Marquez,E., Lopez-Perez,A., Hornblad,A. and
            von Hofsten,J.
  TITLE     Pax3 loss of function delays tumour progression in kRAS-induced
            zebrafish rhabdomyosarcoma models
  JOURNAL   Sci Rep 12 (1), 17149 (2022)
   PUBMED   36229514
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 509)
  AUTHORS   Ragland,J.W. and Raible,D.W.
  TITLE     Signals derived from the underlying mesoderm are dispensable for
            zebrafish neural crest induction
  JOURNAL   Dev Biol 276 (1), 16-30 (2004)
   PUBMED   15531361
  REMARK    Erratum:[Dev Biol. 2005 Mar 1;279(1):268-9]
REFERENCE   7  (residues 1 to 509)
  AUTHORS   Lewis,J.L., Bonner,J., Modrell,M., Ragland,J.W., Moon,R.T.,
            Dorsky,R.I. and Raible,D.W.
  TITLE     Reiterated Wnt signaling during zebrafish neural crest development
  JOURNAL   Development 131 (6), 1299-1308 (2004)
   PUBMED   14973296
REFERENCE   8  (residues 1 to 509)
  AUTHORS   Das,T., Purkayastha-Mukherjee,C., D'Angelo,J. and Weir,M.
  TITLE     A conserved F-box gene with unusual transcript localization
  JOURNAL   Dev Genes Evol 212 (3), 134-140 (2002)
   PUBMED   11976951
REFERENCE   9  (residues 1 to 509)
  AUTHORS   Hauptmann,G., Soll,I. and Gerster,T.
  TITLE     The early embryonic zebrafish forebrain is subdivided into
            molecularly distinct transverse and longitudinal domains
  JOURNAL   Brain Res Bull 57 (3-4), 371-375 (2002)
   PUBMED   11922991
REFERENCE   10 (residues 1 to 509)
  AUTHORS   Cretekos,C.J. and Grunwald,D.J.
  TITLE     alyron, an insertional mutation affecting early neural crest
            development in zebrafish
  JOURNAL   Dev Biol 210 (2), 322-338 (1999)
   PUBMED   10357894
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000002.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588723.1921823.1,
                                           SRR32588734.3724288.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505371,
                                           SAMEA3505372 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="2"
                     /map="2"
     Protein         1..509
                     /product="paired box protein Pax-3a"
                     /note="etID309899.2; paired box gene 3; paired box
                     homeotic gene 3; paired box gene 3a"
                     /calculated_mol_wt=55540
     Region          34..159
                     /region_name="PAX"
                     /note="Paired Box domain; smart00351"
                     /db_xref="CDD:128645"
     Site            order(39..40,45,47..49,51,56,68,70,79,82,84..85,89,
                     98..104,106..107,109..110,129..131,150,152..153,156,159)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238076"
     Region          221..277
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     Region          350..394
                     /region_name="Pax7"
                     /note="Paired box protein 7; pfam12360"
                     /db_xref="CDD:403540"
     CDS             1..509
                     /gene="pax3a"
                     /gene_synonym="pax3; zgc:92547"
                     /coded_by="NM_131277.2:277..1806"
                     /db_xref="GeneID:30532"
                     /db_xref="ZFIN:ZDB-GENE-980526-52"
ORIGIN      
        1 mtalaggisr mmrptppqny prggyslevs tplgqgrvnq lggvfingrp lpnhirhkiv
       61 emahhgirpc visrqlrvsh gcvskilcry qetgsirpga iggskpkqst tpdvekkiee
      121 ykrenpgmfs weirdkllkd gicdrnnvps vssisrmlrc kfggngdede dddevekrei
      181 eenerrakhs idgilgdrss hsdegsdvds epglplkrkq rrsrttftae qleelerafe
      241 rthypdiytr eelaqraklt earvqvwfsn rrarwrkqag anqlmafnhl ipggfppsam
      301 sslqpyqlad spyppssisq vseqpstvhr pqplpptsvh qsglgsgpga qegssaycls
      361 sgrhgfsgys dgyvaapgha npvnpsisng lpsqvmglln pgavphqpqs dfalspltgg
      421 lepstgmpas chssqrleal pglpsmpalp ssqsycpssy sspgysvdhv asyqysqygq
      481 skvntstvtt verlsrvypl krasfglve
//
LOCUS       NP_001116087             436 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger protein [Danio rerio].
ACCESSION   NP_001116087 XP_021331425
VERSION     NP_001116087.2
DBSOURCE    REFSEQ: accession NM_001122615.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 436)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (residues 1 to 436)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000004.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_021331425.2, NP_001116087.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588721.1235515.1,
                                           SRR32588722.18744808.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476741, SAMEA4476770
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="4"
                     /map="4"
     Protein         1..436
                     /product="zinc finger protein"
                     /calculated_mol_wt=50157
     CDS             1..436
                     /gene="zgc:174646"
                     /coded_by="NM_001122615.2:110..1420"
                     /db_xref="GeneID:100142637"
                     /db_xref="ZFIN:ZDB-GENE-080305-6"
ORIGIN      
        1 mafikeened vkieetfrvk qedlqeqtdl ikdyeeskee hrvkiegkth letdgilkmr
       61 dkscftctqc gkslankskl kihmrihtge rpftctqcgk sfchlanlnq hmmihtgekp
      121 ftctqcgksf shsanlnqhm mihtgekpft chqcgksfsk sstlyrhmri htgeqpftct
      181 qcgksfnqps nlylhmriht gekpftctqc gknfihsshl nehmmihtge kpftctqcgr
      241 sfslsstlnr hmrihtgekp ftctqcgksf sqsaslnrhm rihtgespft ctqcgksfsl
      301 ssylnkhlri htgekpftct rcgksfrhss hlnqhmmihn rekpftctcc gksfrhsssl
      361 nqhmmihtge kpftctqcgk sfslssyfkr hmkihtgvrd ymclecektf itaaelkrhq
      421 rihtgerglp rnfent
//
LOCUS       NP_001245157            1548 aa            linear   VRT 18-JUN-2025
DEFINITION  protein TALPID3 isoform 3 [Danio rerio].
ACCESSION   NP_001245157
VERSION     NP_001245157.2
DBSOURCE    REFSEQ: accession NM_001258228.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 1548)
  AUTHORS   Noble,A.R., Masek,M., Hofmann,C., Cuoco,A., Rusterholz,T.D.S.,
            Ozkoc,H., Greter,N.R., Phelps,I.G., Vladimirov,N., Kollmorgen,S.,
            Stoeckli,E. and Bachmann-Gagescu,R.
  TITLE     Shared and unique consequences of Joubert Syndrome gene dysfunction
            on the zebrafish central nervous system
  JOURNAL   Biol Open 13 (11) (2024)
   PUBMED   39400299
REFERENCE   2  (residues 1 to 1548)
  AUTHORS   Ojeda Naharros,I., Cristian,F.B., Zang,J., Gesemann,M.,
            Ingham,P.W., Neuhauss,S.C.F. and Bachmann-Gagescu,R.
  TITLE     The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8
            activation in zebrafish photoreceptor outer segment formation and
            maintenance
  JOURNAL   Sci Rep 8 (1), 2211 (2018)
   PUBMED   29396404
  REMARK    GeneRIF: While localization of the small GTPase Rab8a, which plays
            an important role in basal body docking, appears unaffected in
            talpid3-/- photoreceptors, overexpression of constitutively active
            Rab8a rescues outer segment formation, indicating that the role of
            Ta3 in early ciliogenesis lies upstream of Rab8a activation in
            photoreceptors.
            Erratum:[Sci Rep. 2018 Aug 17;8(1):12534. doi:
            10.1038/s41598-018-30671-8. PMID: 30120317]
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1548)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 1548)
  AUTHORS   Zhou,S., Zhao,H., Thongda,W., Zhang,D., Su,B., Yu,D., Peatman,E.
            and Li,C.
  TITLE     Galectins in channel catfish, Ictalurus punctatus: Characterization
            and expression profiling in mucosal tissues
  JOURNAL   Fish Shellfish Immunol 49, 324-335 (2016)
   PUBMED   26767746
REFERENCE   5  (residues 1 to 1548)
  AUTHORS   Ben,J., Elworthy,S., Ng,A.S., van Eeden,F. and Ingham,P.W.
  TITLE     Targeted mutation of the talpid3 gene in zebrafish reveals its
            conserved requirement for ciliogenesis and Hedgehog signalling
            across the vertebrates
  JOURNAL   Development 138 (22), 4969-4978 (2011)
   PUBMED   22028029
  REMARK    GeneRIF: Targeted mutation of the talpid3 gene in zebrafish
            demonstrates that the phenotype of such maternal and zygotic
            (MZta3) mutant zebrafish showed strong similarities to that of
            chick ta3 mutants: absence of primary and motile cilia as well as
            aberrant Hedgehog (Hh) signaling.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000017.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001245157.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQH01014044.1, GFIL01013949.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505371 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1548
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     Protein         1..1548
                     /product="protein TALPID3 isoform 3"
                     /note="talpid 3; ta3; talpid3; protein TALPID3"
                     /calculated_mol_wt=166982
     Region          57..84
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     Region          227..247
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     Region          312..396
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     Region          411..466
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     Region          489..523
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     Region          553..639
                     /region_name="Required for centrosomal localization.
                     /evidence=ECO:0000250"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     Region          639..687
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     Region          1079..1178
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     Region          1350..1370
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (H6D7E6.1)"
     CDS             1..1548
                     /gene="si:ch211-185a18.2"
                     /gene_synonym="kiaa0586"
                     /coded_by="NM_001258228.2:369..5015"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="GeneID:100884142"
                     /db_xref="ZFIN:ZDB-GENE-120119-1"
ORIGIN      
        1 mdsccvsvnn kthfndstss sdaadvlihs tragrdeiqh knqnkvniyi rrlsdsehvh
       61 saderrteip pvnlptasdt agpeeplagi ksnqfaglfg ktsrkekska qstimqteql
      121 kskgedvqis tfsadgrgvv saalrkrsqg apigrnvtvq vlnqdrsqtp arvqpdpafp
      181 lgdpgtsasv aaitaatlaa taplmkaqse meaqisrvsa elkrlqaaeg svlpgrtart
      241 dsssagraah leeqlniliq qrlqhletiq cqqiqlqnrl lgsaldvvas rgnssgvsqi
      301 dslplqisgn rsirlsatdn psagrpasvs mdvyrerqtg ghkspletpa prkvipkpth
      361 wtsststnrp pkssfknqgn grlqdqspnn rrspercalq svgverfama tadnsqpeqs
      421 resqmpskas vtrsaqedgs sfvngqneqe hqgeptnvss ssttvqkase mlqdlgrlkn
      481 emrsllqtad afpapnakst qssrsrhlap vatapppatt pismppepvd viavraaaln
      541 rasvlksiqp ptsmfedagl vlrqvrqskk tleenleail rakdgevlht qlealsknrd
      601 vreelrikkt vdawintlsk eiqddlares serivdaavs rreagqrtra easaaakkts
      661 vraqagntra htrqpapavr nkpavkqeat qpvvlksqdd eeylarlygk alydgqrrtl
      721 kkspylrfns ptpkskpqrp kivetvkgvk mkssktqtsq yvgdvsamqh svsephfifs
      781 psdpdkqqqq pgspvrgyli pmaiplgkpr vdcqppvpsr viitdkpaiv ttsfppitvv
      841 eskpttairk pnaillevqs apkkrtpqlq iqvqpgvnie salcssrqas ptpvipaesi
      901 lpplsnhate dphahedqee nifpgtnfla qadisqetng glpdspiefk glpsppaaly
      961 hgpvfppvpt qstpltepil ntiqqretle nrlvdwveqq vmarvitgmf phpaqadpvh
     1021 qsepensvas diveaagggg lqlfvdtgvp vdsevirhyv nevlteiias mlgqresqgt
     1081 pttpvqtqda qkedttvptp aptpepslkd ppspvrtpdl sehlstatsp ekppqesasp
     1141 gpdripvgtp ittpipsptr vatpspptpa nqspepgslq ihlwegselp leeeeqpelq
     1201 papvvisvpr vddqeesvih psspvlskpq sppapplppv iqksesssss sesscsssvt
     1261 vtetetaarh isegelllnh gqmaavrvle qegvllpnfm tslngslhgv qdmdydppse
     1321 gqviraphlp ahhdpvlsll armelgpisq sqqpegwwee essgevsegq rpvltaaeei
     1381 vltghslmdq qtirqsrntq isphatltsp gqviaehtga vvedgglsvn lrssdeqkea
     1441 mvyqvdtvss pqpessqmaq tvhrpapllv rqyeeepdfp qlrrlsddaf fgadekgedt
     1501 flhtgggggr gsdvrvmsvr lpsvkqdqes vslssvegdt dssandvf
//
LOCUS       NP_998671                675 aa            linear   VRT 18-JUN-2025
DEFINITION  protein NEDD1 [Danio rerio].
ACCESSION   NP_998671
VERSION     NP_998671.2
DBSOURCE    REFSEQ: accession NM_213506.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 675)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 675)
  AUTHORS   Manning,J.A., Lewis,M., Koblar,S.A. and Kumar,S.
  TITLE     An essential function for the centrosomal protein NEDD1 in
            zebrafish development
  JOURNAL   Cell Death Differ 17 (8), 1302-1314 (2010)
   PUBMED   20150915
  REMARK    GeneRIF: zNEDD1 is essential for survival, as a high level of
            knockdown was embryonic lethal. Partial knockdown of zNEDD1 caused
            abnormalities including an increase in mitotic and apoptotic cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000025.1.
            
            On Jun 18, 2025 this sequence version replaced NP_998671.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058053.1, SRR32588733.2658442.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505388, SAMEA4476730
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="25"
                     /map="25"
     Protein         1..675
                     /product="protein NEDD1"
                     /note="neural precursor cell expressed, developmentally
                     down-regulated 1"
                     /calculated_mol_wt=73371
     CDS             1..675
                     /gene="nedd1"
                     /gene_synonym="fb78g03; wu:fb78g03; zgc:63491"
                     /coded_by="NM_213506.2:192..2219"
                     /db_xref="GeneID:406827"
                     /db_xref="ZFIN:ZDB-GENE-040426-2906"
ORIGIN      
        1 medvtrlvss gdclkiwdss smtvveqfnp hsathpvaqv cwsssnqyvv sassigdklv
       61 vsslksspvp vmelgegkkq trvslnstsq flvsggldnt vniwdlktkr lhrtlkdhke
      121 evtcvsfngg dsyiasgsts gdiilhsitt nlsskpfghg pnvpihdlry slvkrsllgt
      181 vsdsgsvalw dantqkelhl fegahkapcs glafspandl lfvtvgldkk ivcydtsski
      241 vfrnkqvesp ltaidftpdg aglvvgstqg riylydlrnl sapvkintah ktsvtcirfq
      301 nstsklkstk ssskssqsnk risvklgssq qtgpstptst vppivsgsef pgdgqaqvpg
      361 psaevfsrea egqlsqdqmp nvekfssigr nslnldifsp lndgfkshgf adtsrnggsi
      421 dvfsreaegq qtadrfrvgr nsldifspvr ddykghrlsd vssgkkdfey lphfpggssq
      481 rktplgtpgs rcyspsvvqt ppikeeestt tppqqtdvqn gtkveksngv rqeydaittp
      541 paaqstriqs vqpqfntpep sqrrdlstql tydspisrap appaaaaaap aaavdsaplt
      601 svqmnfvrnm ihealedfrd tchrdiinlq vemvrqfyiq lneihgliek ysvndslvee
      661 ierlkeenkr lrany
//
LOCUS       NP_956928                645 aa            linear   VRT 18-JUN-2025
DEFINITION  amyloid beta A4 precursor protein-binding family B member
            1-interacting protein [Danio rerio].
ACCESSION   NP_956928 XP_005162545 XP_698714
VERSION     NP_956928.2
DBSOURCE    REFSEQ: accession NM_200634.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 645)
  AUTHORS   Gunawan,F., Gentile,A., Fukuda,R., Tsedeke,A.T.,
            Jimenez-Amilburu,V., Ramadass,R., Iida,A., Sehara-Fujisawa,A. and
            Stainier,D.Y.R.
  TITLE     Focal adhesions are essential to drive zebrafish heart valve
            morphogenesis
  JOURNAL   J Cell Biol 218 (3), 1039-1054 (2019)
   PUBMED   30635353
REFERENCE   2  (residues 1 to 645)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 645)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 645)
  AUTHORS   Hsu,C.H., Lin,J.S., Po Lai,K., Li,J.W., Chan,T.F., You,M.S.,
            Tse,W.K. and Jiang,Y.J.
  TITLE     A new mib allele with a chromosomal deletion covering foxc1a
            exhibits anterior somite specification defect
  JOURNAL   Sci Rep 5, 10673 (2015)
   PUBMED   26039894
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000024.1.
            
            On Jun 18, 2025 this sequence version replaced NP_956928.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQH01004715.1,
                                           SRR32588714.34445135.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505371 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="24"
                     /map="24"
     Protein         1..645
                     /product="amyloid beta A4 precursor protein-binding family
                     B member 1-interacting protein"
                     /note="APBB1-interacting protein 1"
                     /calculated_mol_wt=70724
     Region          82..141
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6PFT9.1)"
     CDS             1..645
                     /gene="apbb1ip"
                     /gene_synonym="zgc:63968"
                     /coded_by="NM_200634.2:126..2063"
                     /db_xref="GeneID:393607"
                     /db_xref="ZFIN:ZDB-GENE-040426-1318"
ORIGIN      
        1 mddidamfsd mlqemdlltq sldaevdsap lakpptipep qemnfsigfa nfneslndle
       61 dndldalmad lvadisatee kfaterdtsk gsvsvapaps kpqsnfslpa sfdsskpats
      121 snsiaapppp pafkpskeee eeqlkadkik laleklkeak vkklvvkvei tdgssktlmv
      181 derqtvrdvm dnlfekthcd cnvdwsvcet npdlqteraf edhenlvepl stwtrdtenk
      241 vlfqekkhky evfknpqify lwkkdkkslk dmkekdkeql leenfcgasv ivpdlegvly
      301 lkedgkkswk qryfllrasg lyyspkgktk asrdlvclvq fdnvnvyyck eyrikykapt
      361 dhcfmlkhpq iqkesqyikf mccddewsmn lwvtgirvak ygkqlydnyk aavrkasgsa
      421 swanrtiqas stastpsptp kakaanghap qppvenkvps nqsslppppp smdflppppp
      481 dpmfpppppa ppappappvp vsstkvnkfp pppkfpqssf pppmddlppp ppppeiadlp
      541 pdflppppps fgshggeslp ppppdpvasl pppppaftsa ggappppppp ppppapapaa
      601 nnpagsvrkv appppkrttp qltapsggdf mselmnamqk krtqp
//
LOCUS       NP_001373594             232 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger protein-like [Danio rerio].
ACCESSION   NP_001373594 XP_017214342
VERSION     NP_001373594.2
DBSOURCE    REFSEQ: accession NM_001386665.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 232)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000013.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001373594.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EH435370.1, SRR32588732.21541678.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505375, SAMEA4476738
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="13"
                     /map="13"
     Protein         1..232
                     /product="zinc finger protein-like"
                     /calculated_mol_wt=26966
     CDS             1..232
                     /gene="si:dkeyp-2e4.7"
                     /coded_by="NM_001386665.2:113..811"
                     /db_xref="GeneID:108191950"
                     /db_xref="ZFIN:ZDB-GENE-061009-51"
ORIGIN      
        1 mkpviknees lqgdpestnn dvetlvlskt egsaalfcrr lkyrvktdet sdqsssdtdt
       61 edelpistsp tpgedfimri htgeapyvce lcgkafkrkh wlkehfyiht gvkrkrkkrl
      121 scdqcemkfe cssvlqghln khrgerpfac vqcdktyfnq hdlkqhlrdc hsekkhgcyl
      181 cgnefsrrsl lqkhmrihtg erpyscphce ktfpykysfe mhvksavcrr dk
//
LOCUS       NP_998389                725 aa            linear   VRT 18-JUN-2025
DEFINITION  nucleolar GTP-binding protein 2 [Danio rerio].
ACCESSION   NP_998389 XP_001333023
VERSION     NP_998389.2
DBSOURCE    REFSEQ: accession NM_213224.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 725)
  AUTHORS   Covello,G., Rossello,F.J., Filosi,M., Gajardo,F., Duchemin,A.L.,
            Tremonti,B.F., Eichenlaub,M., Polo,J.M., Powell,D., Ngai,J.,
            Allende,M.L., Domenici,E., Ramialison,M. and Poggi,L.
  TITLE     Transcriptome analysis of the zebrafish atoh7-/- Mutant, lakritz,
            highlights Atoh7-dependent genetic networks with potential
            implications for human eye diseases
  JOURNAL   FASEB Bioadv 2 (7), 434-448 (2020)
   PUBMED   32676583
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 725)
  AUTHORS   Gallagher,T.L., Tietz,K.T., Morrow,Z.T., McCammon,J.M.,
            Goldrich,M.L., Derr,N.L. and Amacher,S.L.
  TITLE     Pnrc2 regulates 3'UTR-mediated decay of segmentation
            clock-associated transcripts during zebrafish segmentation
  JOURNAL   Dev Biol 429 (1), 225-239 (2017)
   PUBMED   28648842
REFERENCE   3  (residues 1 to 725)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 725)
  AUTHORS   Essers,P.B., Pereboom,T.C., Goos,Y.J., Paridaen,J.T. and
            Macinnes,A.W.
  TITLE     A comparative study of nucleostemin family members in zebrafish
            reveals specific roles in ribosome biogenesis
  JOURNAL   Dev Biol 385 (2), 304-315 (2014)
   PUBMED   24211311
REFERENCE   5  (residues 1 to 725)
  AUTHORS   Paridaen,J.T., Janson,E., Utami,K.H., Pereboom,T.C., Essers,P.B.,
            van Rooijen,C., Zivkovic,D. and MacInnes,A.W.
  TITLE     The nucleolar GTP-binding proteins Gnl2 and nucleostemin are
            required for retinal neurogenesis in developing zebrafish
  JOURNAL   Dev Biol 355 (2), 286-301 (2011)
   PUBMED   21565180
  REMARK    GeneRIF: The nucleolar GTP-binding proteins Gnl2 and nucleostemin
            are required for retinal neurogenesis in developing zebrafish.
REFERENCE   6  (residues 1 to 725)
  AUTHORS   Encinas,P., Rodriguez-Milla,M.A., Novoa,B., Estepa,A., Figueras,A.
            and Coll,J.
  TITLE     Zebrafish fin immune responses during high mortality infections
            with viral haemorrhagic septicemia rhabdovirus. A proteomic and
            transcriptomic approach
  JOURNAL   BMC Genomics 11, 518 (2010)
   PUBMED   20875106
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000016.1.
            
            On Jun 18, 2025 this sequence version replaced NP_998389.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC056293.1, SRR32588727.2703565.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505370, SAMEA3505371
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..725
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="16"
                     /map="16"
     Protein         1..725
                     /product="nucleolar GTP-binding protein 2"
                     /note="guanine nucleotide binding protein-like 2
                     (nucleolar)"
                     /calculated_mol_wt=82607
     CDS             1..725
                     /gene="gnl2"
                     /gene_synonym="wu:fc15c12; zgc:65800; zgc:77319"
                     /coded_by="NM_213224.2:115..2292"
                     /db_xref="GeneID:793727"
                     /db_xref="ZFIN:ZDB-GENE-040426-2317"
ORIGIN      
        1 mvkakfkgks sintsnsssn pdrvkgaggn nmrdratikr lnmyrqkqrc nsrgkvikpl
       61 qyqntvapgt varvepnikw fantkvikqs slqkfqeemn avkkdpyrvv mrqsklpmsl
      121 lhdrikahns kvhildtetf ettfgpkaqr krpnlsvgel kefaeqaevs aqsysaekdr
      181 dlvsedsgvk eeareeifkk gqskriwgel ykvidssdvi iqvldardpm gtrsqsiety
      241 lkkekpwkhl ifvlnkcdli ptwvtkhwva vlsqeyptla fhasltnsfg kgsliqllrq
      301 fgklhsdkkq isvgfigypn vgkssiintl rskkvcnvap lagetkvwqy itlmrrifli
      361 dcpgvvypsd dnetdivlkg vvqvekirnp edhigavler akaeyiqkty ripswssaed
      421 fleklafrtg kllkggepdl ptvskmvlnd wqrgripffv kppgvetdee nkaqamlemp
      481 emesemdele nrleaqdvee asssqheeqk llkkkkeevq klfndvkqnf gkinvapefs
      541 eedlvpvemp dmmdasgsed eeneeeeeed edkaeeetge qqeeessvsd stpkagkkst
      601 qevnkemdek iaklkhfldr akskhfsair ipkglservf tetvakqnaa knqqqkavkq
      661 gkrrravede paqpakltsk ekrrieraqk vkkvgvryye thnvknknkn rkipsdgkka
      721 nrakr
//
LOCUS       NP_001428528             232 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger protein-like [Danio rerio].
ACCESSION   NP_001428528
VERSION     NP_001428528.1
DBSOURCE    REFSEQ: accession NM_001441599.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 232)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000013.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588729.38321754.1,
                                           SRR32588722.2114067.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476772, SAMEA4476784
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="13"
                     /map="13"
     Protein         1..232
                     /product="zinc finger protein-like"
                     /calculated_mol_wt=26966
     CDS             1..232
                     /gene="si:dkeyp-2e4.7"
                     /coded_by="NM_001441599.1:109..807"
                     /db_xref="GeneID:108191950"
                     /db_xref="ZFIN:ZDB-GENE-061009-51"
ORIGIN      
        1 mkpviknees lqgdpestnn dvetlvlskt egsaalfcrr lkyrvktdet sdqsssdtdt
       61 edelpistsp tpgedfimri htgeapyvce lcgkafkrkh wlkehfyiht gvkrkrkkrl
      121 scdqcemkfe cssvlqghln khrgerpfac vqcdktyfnq hdlkqhlrdc hsekkhgcyl
      181 cgnefsrrsl lqkhmrihtg erpyscphce ktfpykysfe mhvksavcrr dk
//
LOCUS       NP_001378811             311 aa            linear   MAM 18-JUN-2025
DEFINITION  olfactory receptor family 1 subfamily J member 42 [Equus caballus].
ACCESSION   NP_001378811 XP_070106491
VERSION     NP_001378811.2
DBSOURCE    REFSEQ: accession NM_001391882.2
KEYWORDS    RefSeq.
SOURCE      Equus caballus (horse)
  ORGANISM  Equus caballus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. This
            record has been curated by NCBI staff in collaboration with Tsviya
            Olender. The reference sequence was derived from JBFNWK010000025.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_070106491.1, NP_001378811.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: This record was generated from genomic coordinates
            provided by Tsviya Olender (Weizmann Institute of Science).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR31307409.1064228.1,
                                           SRR31307410.1766232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA104728708, SAMEA104728714
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Equus caballus"
                     /db_xref="taxon:9796"
                     /chromosome="25"
                     /map="25"
     Protein         1..311
                     /product="olfactory receptor family 1 subfamily J member
                     42"
                     /calculated_mol_wt=35134
     CDS             1..311
                     /gene="OR1J42"
                     /coded_by="NM_001391882.2:456..1391"
                     /db_xref="GeneID:119645904"
ORIGIN      
        1 mrpenkssms eflllglpip leqqgiffal flgmyfttvl gnlliiwlig ldsrlhtpmy
       61 fflshlafsd iflssvtvpk mlknmqtqqp sipyvgcisq mcliivfgcl dnfllavmay
      121 dryvaicqpl hyttvmrqel cvslvagswf fscghallha lllvqlsfca dnaipnfcdl
      181 pallkiscsd iflnelvift egamvvilpf fsilgsyihi wmtvlrvpsr rrlfkvfstc
      241 gshlfvvsly ygtiagvylf sftrssnekd liasvmyavv tpmlnpfiys lrnrdikhal
      301 eifvnkakfl k
//
LOCUS       NP_001186899             474 aa            linear   VRT 18-JUN-2025
DEFINITION  angiopoietin-related protein 1b precursor [Danio rerio].
ACCESSION   NP_001186899 XP_073768735
VERSION     NP_001186899.2
DBSOURCE    REFSEQ: accession NM_001199970.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 474)
  AUTHORS   Li,Y.F., Canario,A.V.M., Power,D.M. and Campinho,M.A.
  TITLE     Ioxynil and diethylstilbestrol disrupt vascular and heart
            development in zebrafish
  JOURNAL   Environ Int 124, 511-520 (2019)
   PUBMED   30685453
REFERENCE   2  (residues 1 to 474)
  AUTHORS   Briolat,V., Jouneau,L., Carvalho,R., Palha,N., Langevin,C.,
            Herbomel,P., Schwartz,O., Spaink,H.P., Levraud,J.P. and Boudinot,P.
  TITLE     Contrasted innate responses to two viruses in zebrafish: insights
            into the ancestral repertoire of vertebrate IFN-stimulated genes
  JOURNAL   J Immunol 192 (9), 4328-4341 (2014)
   PUBMED   24683187
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000002.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_073768735.1, NP_001186899.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588714.24624442.1,
                                           SRR32588717.45983312.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505374 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="2"
                     /map="2"
     Protein         1..474
                     /product="angiopoietin-related protein 1b precursor"
                     /note="angiopoietin-like protein 1"
                     /calculated_mol_wt=51446
     sig_peptide     1..23
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2826
     CDS             1..474
                     /gene="angptl1b"
                     /gene_synonym="fi40b08; wu:fi40b08"
                     /coded_by="NM_001199970.2:79..1503"
                     /db_xref="GeneID:334311"
                     /db_xref="ZFIN:ZDB-GENE-030131-6243"
ORIGIN      
        1 mcpqvwmfcw flcvlwcvri sssssrqrrq meapdpqqqq qqcsytflip eqkitgpica
       61 srgpslpdpe rvtrtdmsel rqtlsrqrre metlrmmvdv dgdmvqemkl lrkesrnmns
      121 rvtqlymqll heilrkrdss lelaalqnrl lngsaaalrl sagyrelqqr vsvlaervns
      181 qaellallee rcvrvygrqs rdppppplpq vlpenipvfv prvsneiqsn swteeqrtga
      241 aaadtgerpa qnnsslkgpf rdcyaalqag hsvsgaillq pddtltpvqa wcehdvdrgg
      301 wtliqrrkdg avnfsrdwds yklgfgdvdg ehwlgldtiy slgrqeeykl lvemedwmek
      361 kvyaayssfh lepesqsyrl rlglyqgnag dsltshngrq fttldrdhda fsgncahfqk
      421 ggwwynacgq tnlngvwysg gvyrsrfqdg ifwadygggf ysmksvrmmi rpid
//
LOCUS       NP_001076468             517 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger and BTB domain-containing protein 49 [Danio rerio].
ACCESSION   NP_001076468
VERSION     NP_001076468.2
DBSOURCE    REFSEQ: accession NM_001082999.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 517)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000014.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001076468.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC133104.1, SRR26395028.261430.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505371 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="14"
                     /map="14"
     Protein         1..517
                     /product="zinc finger and BTB domain-containing protein
                     49"
                     /calculated_mol_wt=56014
     CDS             1..517
                     /gene="zbtb49"
                     /gene_synonym="zgc:158483"
                     /coded_by="NM_001082999.2:35..1588"
                     /db_xref="GeneID:100009630"
                     /db_xref="ZFIN:ZDB-GENE-070209-170"
ORIGIN      
        1 mdsvsvhsvy vlqqlqeqri qgllcdcmlv vkgvcfkahk nvlaafssyf rslfqnspaq
       61 ksdvfhlsiq dvsgigqlld ymytshleln qenvhtllei gqslqvlnvl nmchaflkpc
      121 vsadsasscc vsagpecvsg pgasepqepp hthklrsfys rqylqqspaa gpapsgpgap
      181 qhkktlylkk fnylrsqeee eercagghap cgpatpssad ttpsdlcvtp dlcvtsdpae
      241 aaelertpea epgntgpqgq eqrsgvsggg nkyccevcgk tfkhpsnlel hkrshtgekp
      301 fqcsvcgkaf sqagnlqthl rrhsgekpyi celcgksfaa sgdvqrhiii hsgarphlcd
      361 vcgrgfsnfs nlkehkkthr aereftcdqc gksfnmqrkl lkhksrhsgd kpyccqtcgk
      421 cfagsgdlqr hvrshtgerp yvcdacgksf srtavlrrhr sagvcvssta apecvcapqr
      481 pgevcvssea apepgpeelc ssgalwgram ktlqsdl
//
LOCUS       NP_001092915             422 aa            linear   VRT 18-JUN-2025
DEFINITION  endothelin receptor type Aa precursor [Danio rerio].
ACCESSION   NP_001092915 XP_005160021 XP_073807123 XP_687609
VERSION     NP_001092915.2
DBSOURCE    REFSEQ: accession NM_001099445.3
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 422)
  AUTHORS   Okeke,C., Paulding,D., Riedel,A., Paudel,S., Phelan,C., Teng,C.S.
            and Barske,L.
  TITLE     Control of cranial ectomesenchyme fate by Nr2f nuclear receptors
  JOURNAL   Development 149 (23) (2022)
   PUBMED   36367707
REFERENCE   2  (residues 1 to 422)
  AUTHORS   Kowatschew,D. and Korsching,S.I.
  TITLE     An Ancient Adenosine Receptor Gains Olfactory Function in Bony
            Vertebrates
  JOURNAL   Genome Biol Evol 13 (9) (2021)
   PUBMED   34499158
REFERENCE   3  (residues 1 to 422)
  AUTHORS   Postlethwait,J.H., Massaquoi,M.S., Farnsworth,D.R., Yan,Y.L.,
            Guillemin,K. and Miller,A.C.
  TITLE     The SARS-CoV-2 receptor and other key components of the
            Renin-Angiotensin-Aldosterone System related to COVID-19 are
            expressed in enterocytes in larval zebrafish
  JOURNAL   Biol Open 10 (3) (2021)
   PUBMED   33757938
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 422)
  AUTHORS   Postlethwait,J.H., Farnsworth,D.R. and Miller,A.C.
  TITLE     An intestinal cell type in zebrafish is the nexus for the
            SARS-CoV-2 receptor and the Renin-Angiotensin-Aldosterone System
            that contributes to COVID-19 comorbidities
  JOURNAL   bioRxiv (2020)
   PUBMED   32908984
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 422)
  AUTHORS   Chen,J.W., Niu,X., King,M.J., Noedl,M.T., Tabin,C.J. and
            Galloway,J.L.
  TITLE     The mevalonate pathway is a crucial regulator of tendon cell
            specification
  JOURNAL   Development 147 (12) (2020)
   PUBMED   32467241
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 422)
  AUTHORS   Braasch,I., Volff,J.N. and Schartl,M.
  TITLE     The endothelin system: evolution of vertebrate-specific
            ligand-receptor interactions by three rounds of genome duplication
  JOURNAL   Mol Biol Evol 26 (4), 783-799 (2009)
   PUBMED   19174480
REFERENCE   7  (residues 1 to 422)
  AUTHORS   Nair,S., Li,W., Cornell,R. and Schilling,T.F.
  TITLE     Requirements for Endothelin type-A receptors and Endothelin-1
            signaling in the facial ectoderm for the patterning of skeletogenic
            neural crest cells in zebrafish
  JOURNAL   Development 134 (2), 335-345 (2007)
   PUBMED   17166927
  REMARK    GeneRIF: Edn1 from the pharyngeal ectoderm signals through Ednra
            proteins to direct early dorsoventral patterning of the
            skeletogenic neural crest.
REFERENCE   8  (residues 1 to 422)
  AUTHORS   Woods,I.G., Wilson,C., Friedlander,B., Chang,P., Reyes,D.K.,
            Nix,R., Kelly,P.D., Chu,F., Postlethwait,J.H. and Talbot,W.S.
  TITLE     The zebrafish gene map defines ancestral vertebrate chromosomes
  JOURNAL   Genome Res 15 (9), 1307-1314 (2005)
   PUBMED   16109975
REFERENCE   9  (residues 1 to 422)
  AUTHORS   Clouthier,D.E. and Schilling,T.F.
  TITLE     Understanding endothelin-1 function during craniofacial development
            in the mouse and zebrafish
  JOURNAL   Birth Defects Res C Embryo Today 72 (2), 190-199 (2004)
   PUBMED   15269892
  REMARK    Review article
REFERENCE   10 (residues 1 to 422)
  AUTHORS   Kelsh,R.N., Brand,M., Jiang,Y.J., Heisenberg,C.P., Lin,S.,
            Haffter,P., Odenthal,J., Mullins,M.C., van Eeden,F.J.,
            Furutani-Seiki,M., Granato,M., Hammerschmidt,M., Kane,D.A.,
            Warga,R.M., Beuchle,D., Vogelsang,L. and Nusslein-Volhard,C.
  TITLE     Zebrafish pigmentation mutations and the processes of neural crest
            development
  JOURNAL   Development 123, 369-389 (1996)
   PUBMED   9007256
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000001.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_073807123.1, XP_005160021.1, NP_001092915.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQH01010486.1, GFIL01009165.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505377, SAMEA3505378
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="1"
                     /map="1"
     Protein         1..422
                     /product="endothelin receptor type Aa precursor"
                     /note="endothelin type-A receptor 2; etID40953.1;
                     endothelin receptor A; endothelin receptor type A"
                     /calculated_mol_wt=45385
     sig_peptide     1..25
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2578
     Region          78..377
                     /region_name="7tmA_ET-AR"
                     /note="endothelin A (or endothelin-1) receptor, member of
                     the class A family of seven-transmembrane G
                     protein-coupled receptors; cd15975"
                     /db_xref="CDD:320641"
     Region          79..105
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320641"
     Region          112..138
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320641"
     Site            order(134,137..138,155..160,162..163,166,211,213..217,249,
                     252..254,256..258,260..261,316,319..320,322..323,326,
                     344..345,347..349,352,355..356)
                     /site_type="other"
                     /note="putative peptide ligand binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:320641"
     Region          155..185
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320641"
     Region          197..217
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320641"
     Region          249..274
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320641"
     Region          296..326
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320641"
     Region          345..370
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320641"
     CDS             1..422
                     /gene="ednraa"
                     /gene_synonym="ednr-a; ednra; Ednra2; parade; pde;
                     wu:fb75g12"
                     /coded_by="NM_001099445.3:307..1575"
                     /db_xref="GeneID:114550"
                     /db_xref="ZFIN:ZDB-GENE-010906-2"
ORIGIN      
        1 maittlqlfl lmavlatggl clingteeaq dalypnstts ktnvhkgfqp ptkkdasvfn
       61 mkhppcrdpt siklyfkyin tiiscivfvv givgnatllk iiyqnkcmrn gpnaliasla
      121 lgdliyitid ipinvykllv tkwpfddssf glflcklvpf lqkasvgitv lnlcalsvdr
      181 yravaswsrv qgvgvpllta ieifsiwvls iilavpeamv fnmitftynn qtirtcmlkp
      241 etdfmnfyvy wkdwwlfgfy fcvplactai fytlmtceml hhrdgslria lsehlkqrre
      301 vakavfclvl ifalcwfplh lsrllkkmvy vpnderrcdl lnfllimdyf ginlatvnsc
      361 inpiilyfvs kkfkncfksc lccwcysnnq vsssgpvngt siqcknhepg nlytdrvrky
      421 sd
//
LOCUS       NP_001007304             392 aa            linear   VRT 18-JUN-2025
DEFINITION  ADP-ribosylation factor GTPase-activating protein 1 isoform 2
            [Danio rerio].
ACCESSION   NP_001007304 XP_001918482 XP_073771538
VERSION     NP_001007304.2
DBSOURCE    REFSEQ: accession NM_001007303.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 392)
  AUTHORS   Bayes,A., Collins,M.O., Reig-Viader,R., Gou,G., Goulding,D.,
            Izquierdo,A., Choudhary,J.S., Emes,R.D. and Grant,S.G.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 392)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000011.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_073771538.1, NP_001007304.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26395012.1109190.1,
                                           SRR26395017.4747.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505371,
                                           SAMEA3505374 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="11"
                     /map="11"
     Protein         1..392
                     /product="ADP-ribosylation factor GTPase-activating
                     protein 1 isoform 2"
                     /calculated_mol_wt=43038
     CDS             1..392
                     /gene="arfgap1"
                     /gene_synonym="wu:fj34h02; zgc:92804"
                     /coded_by="NM_001007303.2:220..1398"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:100149572"
                     /db_xref="ZFIN:ZDB-GENE-041114-130"
ORIGIN      
        1 masprtrrvl kevrtedenn vcfecgafnp qwvsvtygiw iclecsgkhr glgvhlsfvr
       61 svsmdkwkdl elekmkaggn rkfrmflelq ddydpnwslq ekynsraaal frdkvatlad
      121 gkewsmedss arnwtppqak sslssthrss aaagqnhths drafedwlsd dvnsyqnaga
      181 sgaqenryvg fgntpnppkk eedfinnamt siysgwsnft vgaskiasia kdntsklanq
      241 atlkaaelgp tlndnvikpt qekvkegrll demavgisgl avkvqgagak gwkdmtsffs
      301 gkpdgadegs sayeegyqsq dafgapapkr dfwetfgsns alsgnteapa ehkpstgdgw
      361 dawdnnwets ggaqnqnqkp kpqeeswdns gw
//
LOCUS       NP_001019346             948 aa            linear   VRT 18-JUN-2025
DEFINITION  protocadherin 2 gamma 2 precursor [Danio rerio].
ACCESSION   NP_001019346
VERSION     NP_001019346.2
DBSOURCE    REFSEQ: accession NM_001024175.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 948)
  AUTHORS   Chatzopoulou,A., Schoonheim,P.J., Torraca,V., Meijer,A.H.,
            Spaink,H.P. and Schaaf,M.J.
  TITLE     Functional analysis reveals no transcriptional role for the
            glucocorticoid receptor beta-isoform in zebrafish
  JOURNAL   Mol Cell Endocrinol 447, 61-70 (2017)
   PUBMED   28242321
REFERENCE   2  (residues 1 to 948)
  AUTHORS   Tan,Y.P., Li,S., Jiang,X.J., Loh,W., Foo,Y.K., Loh,C.B., Xu,Q.,
            Yuen,W.H., Jones,M., Fu,J., Venkatesh,B. and Yu,W.P.
  TITLE     Regulation of protocadherin gene expression by multiple
            neuron-restrictive silencer elements scattered in the gene cluster
  JOURNAL   Nucleic Acids Res 38 (15), 4985-4997 (2010)
   PUBMED   20385576
REFERENCE   3  (residues 1 to 948)
  AUTHORS   Wu,Q.
  TITLE     Comparative genomics and diversifying selection of the clustered
            vertebrate protocadherin genes
  JOURNAL   Genetics 169 (4), 2179-2188 (2005)
   PUBMED   15744052
REFERENCE   4  (residues 1 to 948)
  AUTHORS   Tada,M.N., Senzaki,K., Tai,Y., Morishita,H., Tanaka,Y.Z.,
            Murata,Y., Ishii,Y., Asakawa,S., Shimizu,N., Sugino,H. and Yagi,T.
  TITLE     Genomic organization and transcripts of the zebrafish Protocadherin
            genes
  JOURNAL   Gene 340 (2), 197-211 (2004)
   PUBMED   15475161
REFERENCE   5  (residues 1 to 948)
  AUTHORS   Noonan,J.P., Grimwood,J., Schmutz,J., Dickson,M. and Myers,R.M.
  TITLE     Gene conversion and the evolution of protocadherin gene cluster
            diversity
  JOURNAL   Genome Res 14 (3), 354-366 (2004)
   PUBMED   14993203
REFERENCE   6  (residues 1 to 948)
  AUTHORS   Zhang,T., Haws,P. and Wu,Q.
  TITLE     Multiple variable first exons: a mechanism for cell- and
            tissue-specific gene regulation
  JOURNAL   Genome Res 14 (1), 79-89 (2004)
   PUBMED   14672974
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000014.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001019346.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588719.2456457.1,
                                           SRR32588730.28197917.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505391, SAMEA4476738
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="14"
                     /map="14"
     Protein         1..948
                     /product="protocadherin 2 gamma 2 precursor"
                     /note="protocadherin cluster 2 gamma 2"
                     /calculated_mol_wt=100315
     sig_peptide     1..29
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=3326
     CDS             1..948
                     /gene="pcdh2g2"
                     /coded_by="NM_001024175.2:133..2979"
                     /db_xref="GeneID:554048"
                     /db_xref="ZFIN:ZDB-GENE-050610-21"
ORIGIN      
        1 mswavrrlcf aaemfgllff vlmahsaygd vsysfpeemk rgsvigniak dlgldvnrls
       61 srkaridteg nrkrycdinl ntgeltvaer idreeicgkk alcvvkqqle lenplelhhf
      121 ilniqdindy spqfkesvik feigesadkg srylleeayd adigmnsvqs ytlqnnehfl
      181 lnvitkehgr kygelvlnke ldreqqkevt liltavdggt pprsgtvaih vtvldandna
      241 pvfsqavykv slpenspvdt vvvtvsatda degqngvvny gfghvsqkil qlfvldsvsg
      301 vikligtidy edesiielpv qakdgqglas ysnvlidivd andnapiiil kslnspipes
      361 alpgtevgii nvqdrdsenn gqvrcsiqqn vpfklvpsik nyyslvttge ldrellseyn
      421 ititatdegs pplsstknih ltvadvndnp pvfqqqnyra hvqennkags sicsvsatdp
      481 dwrqngtvvy sllssdvnga pvssflsing dtgvihavrs fdyeqmksfk vlvlardngs
      541 pplssnvtvs vfisdendns pqilypspeg ntfmtemvpk aaqarslvsk viavdadsgq
      601 nawlsyhiik atdpglftig vhsgeirtqr disesdsmkq nlivsvrdng qpslsatcal
      661 yllvsdnlae vpelkdmshd essskltfyl iialvsvstf fltfiiiila vrfcrrrkpr
      721 llfdgavaip saylppnyae vegagtlrsa ynydaylttg srtsdfkfvr syndgtltad
      781 ltlrktqssv ndlegldaei pdsfqqkpps adwrftqnqr pgpsgaaatp evavgtgpwp
      841 nppteaeqlq almaaanevs eatnflapgt mdlstrygpq ftlqhvpdyr qnvyipgsta
      901 tltsnqqqpq qalpppqasa aiavaqpepp kaaqtpaskk katkkekk
//
LOCUS       NP_001428530             232 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger protein-like [Danio rerio].
ACCESSION   NP_001428530
VERSION     NP_001428530.1
DBSOURCE    REFSEQ: accession NM_001441601.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 232)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000013.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588728.34215378.1,
                                           SRR32588722.18112696.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01765705, SAMN08196788
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="13"
                     /map="13"
     Protein         1..232
                     /product="zinc finger protein-like"
                     /calculated_mol_wt=26966
     CDS             1..232
                     /gene="si:dkeyp-2e4.7"
                     /coded_by="NM_001441601.1:122..820"
                     /db_xref="GeneID:108191950"
                     /db_xref="ZFIN:ZDB-GENE-061009-51"
ORIGIN      
        1 mkpviknees lqgdpestnn dvetlvlskt egsaalfcrr lkyrvktdet sdqsssdtdt
       61 edelpistsp tpgedfimri htgeapyvce lcgkafkrkh wlkehfyiht gvkrkrkkrl
      121 scdqcemkfe cssvlqghln khrgerpfac vqcdktyfnq hdlkqhlrdc hsekkhgcyl
      181 cgnefsrrsl lqkhmrihtg erpyscphce ktfpykysfe mhvksavcrr dk
//
LOCUS       NP_001107110             438 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC798325 [Danio rerio].
ACCESSION   NP_001107110 XP_001338780
VERSION     NP_001107110.2
DBSOURCE    REFSEQ: accession NM_001113638.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 438)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (residues 1 to 438)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000004.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001107110.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588728.2892626.1,
                                           SRR32588729.23832128.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505376 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="4"
                     /map="4"
     Protein         1..438
                     /product="uncharacterized protein LOC798325"
                     /calculated_mol_wt=50547
     CDS             1..438
                     /gene="zgc:171551"
                     /coded_by="NM_001113638.2:117..1433"
                     /db_xref="GeneID:798325"
                     /db_xref="ZFIN:ZDB-GENE-080220-8"
ORIGIN      
        1 mafikeesed lkientftvk qedpeqtelm vlkeeteeln gieekepmvm keetqelkem
       61 eeknqdlmta emstmtkkts prkrdqeikp vgnftcsqcg ksftqkyklr vhirvhtgek
      121 pysceqcgkr fieksklvsh msthtnvrph scpecgkgfk qkqnlaihmr thtgekpfsc
      181 dqcdmsfsqa hylkahmnvh snekpyacqq cgkrfrqiki lrnhiklhtg ekpcacpqcg
      241 mrfihkqrle thmkvhnkai eaikpflcqq cgkgfvqkgt lkihmrvhtg ekpytcsqcg
      301 ksftqksnlk yhmvthtgek pfpcqqcgns fsqkkcleih mrlhngerpy tcsqcgksft
      361 qkgnlnshmr thaekkpflc qqcgksfsqk kcleihmrvh tgerpyiccq cgrsfsqkgn
      421 ldshmrthag ekpfifgq
//
LOCUS       NP_001038699             333 aa            linear   VRT 18-JUN-2025
DEFINITION  Fanconi anemia group F protein [Danio rerio].
ACCESSION   NP_001038699
VERSION     NP_001038699.3
DBSOURCE    REFSEQ: accession NM_001045234.3
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 333)
  AUTHORS   Wang,C., Chen,X., Dai,Y., Zhang,Y., Sun,Y. and Cui,X.
  TITLE     Comparative transcriptome analysis of heat-induced domesticated
            zebrafish during gonadal differentiation
  JOURNAL   BMC Genom Data 23 (1), 39 (2022)
   PUBMED   35641933
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 333)
  AUTHORS   Ramanagoudr-Bhojappa,R., Carrington,B., Ramaswami,M., Bishop,K.,
            Robbins,G.M., Jones,M., Harper,U., Frederickson,S.C., Kimble,D.C.,
            Sood,R. and Chandrasekharappa,S.C.
  TITLE     Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia
            pathway genes in zebrafish revealed their roles in growth, sexual
            development and fertility
  JOURNAL   PLoS Genet 14 (12), e1007821 (2018)
   PUBMED   30540754
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 333)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 333)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 333)
  AUTHORS   Titus,T.A., Yan,Y.L., Wilson,C., Starks,A.M., Frohnmayer,J.D.,
            Bremiller,R.A., Canestro,C., Rodriguez-Mari,A., He,X. and
            Postlethwait,J.H.
  TITLE     The Fanconi anemia/BRCA gene network in zebrafish: embryonic
            expression and comparative genomics
  JOURNAL   Mutat Res 668 (1-2), 117-132 (2009)
   PUBMED   19101574
  REMARK    Review article
REFERENCE   6  (residues 1 to 333)
  AUTHORS   Titus,T.A., Selvig,D.R., Qin,B., Wilson,C., Starks,A.M., Roe,B.A.
            and Postlethwait,J.H.
  TITLE     The Fanconi anemia gene network is conserved from zebrafish to
            human
  JOURNAL   Gene 371 (2), 211-223 (2006)
   PUBMED   16515849
REFERENCE   7  (residues 1 to 333)
  AUTHORS   Woods,I.G., Wilson,C., Friedlander,B., Chang,P., Reyes,D.K.,
            Nix,R., Kelly,P.D., Chu,F., Postlethwait,J.H. and Talbot,W.S.
  TITLE     The zebrafish gene map defines ancestral vertebrate chromosomes
  JOURNAL   Genome Res 15 (9), 1307-1314 (2005)
   PUBMED   16109975
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000025.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001038699.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: GDQQ01049650.1, GFIL01010298.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="25"
                     /map="25"
     Protein         1..333
                     /product="Fanconi anemia group F protein"
                     /note="Fanconi anemia, complementation group F"
                     /calculated_mol_wt=37469
     CDS             1..333
                     /gene="fancf"
                     /coded_by="NM_001045234.3:45..1046"
                     /db_xref="GeneID:692250"
                     /db_xref="ZFIN:ZDB-GENE-060306-3"
ORIGIN      
        1 meavlrhlnn ilellavsrt drvrewdrpt tqrafkwaey ceqlhsryqs nptvrsrles
       61 gltdtnrrlr etfpsyspve fselaqcqhk livyllrnps sphfiiemlf pdqnspsqel
      121 lapqnslvtr ksafsllcct vnttssyygl qtepevrgkl lgkllnsila rpgneehakc
      181 lldsvrcdsa gkvdgfydvi agallcssde sqrfiitwlk esdgglntfc tvispevcav
      241 isrqspefrk lywgalkqwa scleydvtks vwvtsegavs fdvladrlrd linsgeslke
      301 etetalkalt lqdgdfsvkg vsvwtdltlq lki
//
LOCUS       NP_001103195             297 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger protein [Danio rerio].
ACCESSION   NP_001103195 XP_001332272
VERSION     NP_001103195.3
DBSOURCE    REFSEQ: accession NM_001109725.3
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 297)
  AUTHORS   Newman,M., Hin,N., Pederson,S. and Lardelli,M.
  TITLE     Brain transcriptome analysis of a familial Alzheimer's disease-like
            mutation in the zebrafish presenilin 1 gene implies effects on
            energy production
  JOURNAL   Mol Brain 12 (1), 43 (2019)
   PUBMED   31053140
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000004.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001103195.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC152115.1, SRR32588720.1006638.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505374, SAMEA3505377
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="4"
                     /map="4"
     Protein         1..297
                     /product="zinc finger protein"
                     /calculated_mol_wt=34521
     CDS             1..297
                     /gene="zgc:173624"
                     /gene_synonym="si:dkey-262g12.6; si:dkey-262g12.7"
                     /coded_by="NM_001109725.3:112..1005"
                     /db_xref="GeneID:794762"
                     /db_xref="ZFIN:ZDB-GENE-071004-60"
ORIGIN      
        1 mavikvesed lqiedtftvk qedpeeqtel mvlkeetqdl nikqekdqfe inqdsvtdeq
       61 ttttkktrkt rsnggytcsq cgksfaikhn lithirvhtg ekpfscdqcg ksfsqksklp
      121 vhmrvhtker pytctycgks ycqkqylkvh trihtgekpy tctecgksfr qkqylkvhkr
      181 shtgekpfsc cecgkrfyln qylkahmrih tgerpfscdq ceksfsrksk ldvhmrvhtg
      241 lkpfsecgks fcqkqyfkvh mrihtgekpf hcqqcgkgfv qlqslkshis vharekq
//
LOCUS       NP_001373768             176 aa            linear   VRT 18-JUN-2025
DEFINITION  cdc42 effector protein 3-like [Danio rerio].
ACCESSION   NP_001373768 XP_009291035
VERSION     NP_001373768.2
DBSOURCE    REFSEQ: accession NM_001386839.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 176)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000017.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001373768.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EH527489.1, EH501261.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505375, SAMEA3505377
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..176
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     Protein         1..176
                     /product="cdc42 effector protein 3-like"
                     /calculated_mol_wt=19916
     CDS             1..176
                     /gene="LOC100151490"
                     /coded_by="NM_001386839.2:146..676"
                     /db_xref="GeneID:100151490"
ORIGIN      
        1 mplwtsqqrk paplrwrasg rrnrvslnmi slpladfkhl shigldghtd sfgdlsflke
       61 ghnllhqssr seqnlflaca pppkpprvnl eepiwektas errqkssslp lldmededee
      121 qypktlintd qtqtdqiktd qtqtdqtdsa ftfsldlgps ildavlqvme kssnrh
//
LOCUS       NP_955996                411 aa            linear   VRT 18-JUN-2025
DEFINITION  lysosome-associated membrane glycoprotein 1a precursor [Danio
            rerio].
ACCESSION   NP_955996 XP_073770574
VERSION     NP_955996.2
DBSOURCE    REFSEQ: accession NM_199702.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 411)
  AUTHORS   Lee,J.J., Wang,T., Wiggins,K., Lu,P.N., Underwood,C.,
            Ochenkowska,K., Samarut,E., Pollard,L.M., Flanagan-Steet,H. and
            Steet,R.
  TITLE     Dysregulated lysosomal exocytosis drives protease-mediated
            cartilage pathogenesis in multiple lysosomal disorders
  JOURNAL   iScience 27 (4), 109293 (2024)
   PUBMED   38495824
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 411)
  AUTHORS   Gao,G., Guo,S., Zhang,Q., Zhang,H., Zhang,C. and Peng,G.
  TITLE     Kiaa1024L/Minar2 is essential for hearing by regulating cholesterol
            distribution in hair bundles
  JOURNAL   Elife 11, e80865 (2022)
   PUBMED   36317962
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 411)
  AUTHORS   Ikeda,A., Komamizu,M., Hayashi,A., Yamasaki,C., Okada,K.,
            Kawabe,M., Komatsu,M. and Shiozaki,K.
  TITLE     Neu1 deficiency induces abnormal emotional behavior in zebrafish
  JOURNAL   Sci Rep 11 (1), 13477 (2021)
   PUBMED   34188220
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 411)
  AUTHORS   Lescat,L., Veron,V., Mourot,B., Peron,S., Chenais,N., Dias,K.,
            Riera-Heredia,N., Beaumatin,F., Pinel,K., Priault,M., Panserat,S.,
            Salin,B., Guiguen,Y., Bobe,J., Herpin,A. and Seiliez,I.
  TITLE     Chaperone-Mediated Autophagy in the Light of Evolution: Insight
            from Fish
  JOURNAL   Mol Biol Evol 37 (10), 2887-2899 (2020)
   PUBMED   32437540
REFERENCE   5  (residues 1 to 411)
  AUTHORS   Okada,K., Takase,R., Hamaoka,Y., Honda,A., Ikeda,A., Hokazono,Y.,
            Maeda,Y., Hayasaka,O., Kotani,T., Komatsu,M. and Shiozaki,K.
  TITLE     Establishment and characterization of Neu1-knockout zebrafish and
            its abnormal clinical phenotypes
  JOURNAL   Biochem J 477 (15), 2841-2857 (2020)
   PUBMED   32686823
REFERENCE   6  (residues 1 to 411)
  AUTHORS   Wong,M., Newton,L.R., Hartmann,J., Hennrich,M.L., Wachsmuth,M.,
            Ronchi,P., Guzman-Herrera,A., Schwab,Y., Gavin,A.C. and Gilmour,D.
  TITLE     Dynamic Buffering of Extracellular Chemokine by a Dedicated
            Scavenger Pathway Enables Robust Adaptation during Directed Tissue
            Migration
  JOURNAL   Dev Cell 52 (4), 492-508 (2020)
   PUBMED   32059773
REFERENCE   7  (residues 1 to 411)
  AUTHORS   Sun,X., Zhou,Y., Zhang,R., Wang,Z., Xu,M., Zhang,D., Huang,J.,
            Luo,F., Li,F., Ni,Z., Zhou,S., Chen,H., Chen,S., Chen,L., Du,X.,
            Chen,B., Huang,H., Liu,P., Yin,L., Qiu,J., Chen,D., Deng,C.,
            Xie,Y., Luo,L. and Chen,L.
  TITLE     Dstyk mutation leads to congenital scoliosis-like vertebral
            malformations in zebrafish via dysregulated mTORC1/TFEB pathway
  JOURNAL   Nat Commun 11 (1), 479 (2020)
   PUBMED   31980602
  REMARK    Publication Status: Online-Only
REFERENCE   8  (residues 1 to 411)
  AUTHORS   Meireles,A.M., Shen,K., Zoupi,L., Iyer,H., Bouchard,E.L.,
            Williams,A. and Talbot,W.S.
  TITLE     The Lysosomal Transcription Factor TFEB Represses Myelination
            Downstream of the Rag-Ragulator Complex
  JOURNAL   Dev Cell 47 (3), 319-330 (2018)
   PUBMED   30399334
REFERENCE   9  (residues 1 to 411)
  AUTHORS   Sasaki,T., Lian,S., Khan,A., Llop,J.R., Samuelson,A.V., Chen,W.,
            Klionsky,D.J. and Kishi,S.
  TITLE     Autolysosome biogenesis and developmental senescence are regulated
            by both Spns1 and v-ATPase
  JOURNAL   Autophagy 13 (2), 386-403 (2017)
   PUBMED   27875093
REFERENCE   10 (residues 1 to 411)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000001.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_073770574.1, NP_955996.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26395014.90981.1,
                                           SRR26395015.1975285.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505370, SAMEA3505371
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="1"
                     /map="1"
     Protein         1..411
                     /product="lysosome-associated membrane glycoprotein 1a
                     precursor"
                     /note="lysosome-associated membrane glycoprotein 1"
                     /calculated_mol_wt=41358
     sig_peptide     1..21
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2180
     CDS             1..411
                     /gene="lamp1a"
                     /gene_synonym="fc50e01; wu:fc50e01; zgc:64072"
                     /coded_by="NM_199702.2:156..1391"
                     /db_xref="GeneID:324985"
                     /db_xref="ZFIN:ZDB-GENE-030131-3708"
ORIGIN      
        1 maraagvcwt llmgcvfaah avtfevidgn stcikgelna sfsisynttn gtsvsvfalp
       61 asasvserss cgsaavppel alvfgdthth tlsllfsrdq rlyrvsnisl qynlsdgdif
      121 pqsssagvqs vmasvselms arlnstyrcv ssssislsaa vnltlsgvqm eaymssanls
      181 adesvcsadq psttvappps tttspppipp vpergnysvt dgngtvcvla lmglqlnith
      241 tttqnqsvse lmnlqpnqtt vsgscgvtes slrlsdettn ltfsftmnst tqkyylsavs
      301 vsalwpdmsv vfeagntsls alqcsvgrsy vcsaqqmlsv tpvfsintfr lqlqpfnita
      361 nrfstaeecr vdqenmlipi ivgaalaglv livlvaylig rkrthagyqt i
//
LOCUS       NP_001428518            1099 aa            linear   VRT 18-JUN-2025
DEFINITION  uncharacterized protein LOC799740 isoform 1 [Danio rerio].
ACCESSION   NP_001428518 XP_068070572
VERSION     NP_001428518.1
DBSOURCE    REFSEQ: accession NM_001441589.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 1099)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 1099)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000017.1.
            
            On Jun 18, 2025 this sequence version replaced XP_068070572.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588719.6879154.1,
                                           SRR32588729.34624745.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505371 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
                     /map="17"
     Protein         1..1099
                     /product="uncharacterized protein LOC799740 isoform 1"
                     /calculated_mol_wt=123972
     CDS             1..1099
                     /gene="si:ch73-50f9.4"
                     /coded_by="NM_001441589.1:131..3430"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:799740"
                     /db_xref="ZFIN:ZDB-GENE-131122-9"
ORIGIN      
        1 maeervkdsl sgkhsvrsgs cvsrsvslks desrkglppe fseqppssnr sveyelsdsv
       61 dkthcnrksf tdhllrifqd leskifkvlk nelerfrqil qgentqdfvk gsnenqssit
      121 ksaldltllf lremkqdeva dtlenellfi nrlksslkkt yqsvsegiaq qgdstllnni
      181 ytdlyitqga neqvntehei rqieaasrch ksleiqveck hlfeapeqdk qirtvltkgv
      241 agigksvsvq kfvvdwaegk anqdislifp lpfremnlke kekqslkdli tqlfpevkgl
      301 nltrrtrnkv lfildgldec rlplnfagne tchdvsapay ldvlltnlik gnllpsaliw
      361 itsrpaaask ipadcidrlt eirgfndaqk eeyfrkrlad qnlameiieh ikqskslhim
      421 chipvfcwis atvlqnvlke tkvkhkacak tlqespktlt qmythflrfq mqqsrqkydg
      481 kntdgvswdq nfilslgkla yqqlernnvi fyesdlkdcg idvykasvys gmctqifkqe
      541 tgiilgnlyc flhlsiqefi aalyghlyld ikkksvftgq khknkgmthl lktavdkale
      601 sdnghldlyl rfllglslqt nrqllrgllt qqdksdqske eivvyikqkl eenlsperai
      661 nllyclneln dhslmkeiqs hlrdgslssa dlspaqwsal tfvlltseee ldefdlqkfk
      721 ksdeclirls aviksskral lqccnltaqs ceslssalqs sncvlrelel snndlqdsgv
      781 kllscglrsl ncpleilrlq ccnltaqsce slslalqsst cvlreldlsn ndlqdsgvkl
      841 isnglksckl eilrlsgcmv tetgcgflss alssnpthlr eldlsynhpg vsgvkllcqk
      901 ledpnytlak lnvdhagakr itagprkwis hltldpntan telslsaenr eatrviekqp
      961 ypdhpdrfdy hpqvlcresv cgpcyweidw sgdvgacisv syksvsskgn defgcndqsw
     1021 slscyssrfs yghnnrwtdl pvkpisrrig vyvdhraetl rfynicgntv hlvhsvrttf
     1081 tqplyagfki ypgssvklc
//
LOCUS       NP_956062                809 aa            linear   VRT 18-JUN-2025
DEFINITION  myoneurin [Danio rerio].
ACCESSION   NP_956062 XP_073796130 XP_682995 XP_706799 XP_706800
VERSION     NP_956062.2
DBSOURCE    REFSEQ: accession NM_199768.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 809)
  AUTHORS   Yang,S., Ning,G., Hou,Y., Cao,Y., Xu,J., Wu,J., Zhang,T. and
            Wang,Q.
  TITLE     Myoneurin regulates BMP signaling by competing with Ppm1a for Smad
            binding
  JOURNAL   iScience 25 (6), 104495 (2022)
   PUBMED   35712083
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 809)
  AUTHORS   Hou,J., Liu,H., Wang,L., Duan,L., Li,S. and Wang,X.
  TITLE     Molecular Toxicity of Metal Oxide Nanoparticles in Danio rerio
  JOURNAL   Environ Sci Technol 52 (14), 7996-8004 (2018)
   PUBMED   29944347
REFERENCE   3  (residues 1 to 809)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 809)
  AUTHORS   Diotel,N., Rodriguez Viales,R., Armant,O., Marz,M., Ferg,M.,
            Rastegar,S. and Strahle,U.
  TITLE     Comprehensive expression map of transcription regulators in the
            adult zebrafish telencephalon reveals distinct neurogenic niches
  JOURNAL   J Comp Neurol 523 (8), 1202-1221 (2015)
   PUBMED   25556858
REFERENCE   5  (residues 1 to 809)
  AUTHORS   Lee,E., Koo,Y., Ng,A., Wei,Y., Luby-Phelps,K., Juraszek,A.,
            Xavier,R.J., Cleaver,O., Levine,B. and Amatruda,J.F.
  TITLE     Autophagy is essential for cardiac morphogenesis during vertebrate
            development
  JOURNAL   Autophagy 10 (4), 572-587 (2014)
   PUBMED   24441423
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000024.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_073796130.1, NP_956062.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26395039.1424436.1,
                                           SRR26395014.732116.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505370, SAMEA3505371
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="24"
                     /map="24"
     Protein         1..809
                     /product="myoneurin"
                     /calculated_mol_wt=90786
     Region          122..146
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q7ZVR6.1)"
     Region          428..432
                     /region_name="Nuclear localization signal.
                     /evidence=ECO:0000255"
                     /note="propagated from UniProtKB/Swiss-Prot (Q7ZVR6.1)"
     CDS             1..809
                     /gene="mynn"
                     /gene_synonym="wu:fd15c04; zgc:55724"
                     /coded_by="NM_199768.2:144..2573"
                     /db_xref="GeneID:327167"
                     /db_xref="ZFIN:ZDB-GENE-030131-5378"
ORIGIN      
        1 mphithsefl leqlkrqrer sflcdctvsi gqaqyrahhn vlaafseyfs tqsvdagred
       61 ptitldpesv ssaifekllt yiytgdlnmd reeiesvqka asylgmpevv arctlsqdni
      121 knvgspmrqa eyedprspls pddyeplepi seveerellr edragddlvs mdeaqsssdq
      181 tpqrvgkrgr kpktrlyede fevetisaqs grgrgrgrpr grprvrplss dstdqspahq
      241 amspngssts rgsgrprgrp rvrplstane dprnveddpa ankdqevekg neeqkketge
      301 kddgkndtdn peevtafkrg rgrprikpvs tedqntnsen vttnaedgse paktkdsegt
      361 grkrgrprsk pvssedpesv isveisgeea geetsqdaek hteegtedse snpgnsvris
      421 krkrilsrkl kesqagdeee eeeemddefe ndnedwagee evkpvqdkhr picnicgnlf
      481 semsslrrhm rihkglkpyq ctlctrsfrq gnqlkthmri htgekpftct scdarfaqkc
      541 qlvyhcrmhh geekpykcef cgaafatssn lkihirkhsg ekpyecgecg krftqastlm
      601 yhkrrhtgek pyicdtcgma favsssliah nrkhtgvtpy icldcgkpcl tagelrkhmd
      661 vhndiyslkk hsilkhnvvp elettqtskt dptqcplnip idhqgliarv rsalvdsqdh
      721 eiqmepplpi lppetsliiq qsaepqmiiq hadgsepsmi fqhaeaseap mliqhgepge
      781 qvsyvveqye ipataemeht qivivqtid
//
LOCUS       NP_001428523             517 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger and BTB domain-containing protein 49 [Danio rerio].
ACCESSION   NP_001428523 XP_073777163
VERSION     NP_001428523.1
DBSOURCE    REFSEQ: accession NM_001441594.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 517)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000014.1.
            
            On Jun 18, 2025 this sequence version replaced XP_073777163.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26395012.1332919.1,
                                           GFIL01043977.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505370,
                                           SAMEA3505371 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="14"
                     /map="14"
     Protein         1..517
                     /product="zinc finger and BTB domain-containing protein
                     49"
                     /calculated_mol_wt=56014
     CDS             1..517
                     /gene="zbtb49"
                     /gene_synonym="zgc:158483"
                     /coded_by="NM_001441594.1:150..1703"
                     /db_xref="GeneID:100009630"
                     /db_xref="ZFIN:ZDB-GENE-070209-170"
ORIGIN      
        1 mdsvsvhsvy vlqqlqeqri qgllcdcmlv vkgvcfkahk nvlaafssyf rslfqnspaq
       61 ksdvfhlsiq dvsgigqlld ymytshleln qenvhtllei gqslqvlnvl nmchaflkpc
      121 vsadsasscc vsagpecvsg pgasepqepp hthklrsfys rqylqqspaa gpapsgpgap
      181 qhkktlylkk fnylrsqeee eercagghap cgpatpssad ttpsdlcvtp dlcvtsdpae
      241 aaelertpea epgntgpqgq eqrsgvsggg nkyccevcgk tfkhpsnlel hkrshtgekp
      301 fqcsvcgkaf sqagnlqthl rrhsgekpyi celcgksfaa sgdvqrhiii hsgarphlcd
      361 vcgrgfsnfs nlkehkkthr aereftcdqc gksfnmqrkl lkhksrhsgd kpyccqtcgk
      421 cfagsgdlqr hvrshtgerp yvcdacgksf srtavlrrhr sagvcvssta apecvcapqr
      481 pgevcvssea apepgpeelc ssgalwgram ktlqsdl
//
LOCUS       NP_001116097             411 aa            linear   VRT 18-JUN-2025
DEFINITION  zinc finger and BTB domain-containing protein 26 [Danio rerio].
ACCESSION   NP_001116097 XP_005165648 XP_073805752
VERSION     NP_001116097.2
DBSOURCE    REFSEQ: accession NM_001122625.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 411)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000005.1.
            
            On or before Jun 18, 2025 this sequence version replaced
            XP_073805752.1, NP_001116097.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588720.1570706.1,
                                           SRR26395014.1479986.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476755, SAMEA4476780
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="5"
                     /map="5"
     Protein         1..411
                     /product="zinc finger and BTB domain-containing protein
                     26"
                     /calculated_mol_wt=46460
     CDS             1..411
                     /gene="zbtb26"
                     /gene_synonym="si:ch211-236k19.4"
                     /coded_by="NM_001122625.2:73..1308"
                     /db_xref="GeneID:100142649"
                     /db_xref="ZFIN:ZDB-GENE-060526-122"
ORIGIN      
        1 maqdgvilqf nfatfgdsml qkmdalrrdr rfcdvvvrin dlevpghkvv faagspflrd
       61 qfvlqdsnev qiatqqdaev gqklllscyt gtlqfpelel vhyltvasfl qmghiveqct
      121 ealnkfikph evkderassr qpsdftpqrn qaavkkvcde edevdneede fddddddddv
      181 iiqpksppav frnnnsreds pisivkvesl dervpdnfqs rssrsrsptl rspepqhsli
      241 nstvetrpae itvnptaeys mstpgpsgsg kgnlwggcsr ngeksmqwyh qcpkcarvfr
      301 qlenyanhlk mhklfmcllc gktftqkgnl hrhmrvhagi kpfqckicgk tftqkcslld
      361 hlnlhsgdkp hrcnycdmvf ahkpvlrkhl kqihgknsfd nanegslleg l
//
LOCUS       NP_001018624             160 aa            linear   VRT 18-JUN-2025
DEFINITION  interleukin-17C precursor [Danio rerio].
ACCESSION   NP_001018624
VERSION     NP_001018624.2
DBSOURCE    REFSEQ: accession NM_001020788.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 160)
  AUTHORS   Banu,S., Gaur,N., Nair,S., Ravikrishnan,T., Khan,S., Mani,S.,
            Bharathi,S., Mandal,K., Kuram,N.A., Vuppaladadium,S., Ravi,R.,
            Murthy,C.L.N., Quoseena,M., Babu,N.S. and Idris,M.M.
  TITLE     Understanding the complexity of epimorphic regeneration in
            zebrafish caudal fin tissue: A transcriptomic and proteomic
            approach
  JOURNAL   Genomics 114 (2), 110300 (2022)
   PUBMED   35134499
REFERENCE   2  (residues 1 to 160)
  AUTHORS   Pan,C.Y., Wu,J.L., Hui,C.F., Lin,C.H. and Chen,J.Y.
  TITLE     Insights into the antibacterial and immunomodulatory functions of
            the antimicrobial peptide, epinecidin-1, against Vibrio vulnificus
            infection in zebrafish
  JOURNAL   Fish Shellfish Immunol 31 (6), 1019-1025 (2011)
   PUBMED   21925271
REFERENCE   3  (residues 1 to 160)
  AUTHORS   Oehlers,S.H., Flores,M.V., Chen,T., Hall,C.J., Crosier,K.E. and
            Crosier,P.S.
  TITLE     Topographical distribution of antimicrobial genes in the zebrafish
            intestine
  JOURNAL   Dev Comp Immunol 35 (3), 385-391 (2011)
   PUBMED   21093479
REFERENCE   4  (residues 1 to 160)
  AUTHORS   Kumari,J., Larsen,A.N., Bogwald,J. and Dalmo,R.A.
  TITLE     Interleukin-17D in Atlantic salmon (Salmo salar): molecular
            characterization, 3D modelling and promoter analysis
  JOURNAL   Fish Shellfish Immunol 27 (5), 647-659 (2009)
   PUBMED   19716422
REFERENCE   5  (residues 1 to 160)
  AUTHORS   Gunimaladevi,I., Savan,R. and Sakai,M.
  TITLE     Identification, cloning and characterization of interleukin-17 and
            its family from zebrafish
  JOURNAL   Fish Shellfish Immunol 21 (4), 393-403 (2006)
   PUBMED   16677828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000018.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001018624.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR32588722.19485454.1,
                                           SRR32588732.2763267.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA3505377,
                                           SAMEA3505382 [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..160
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="18"
                     /map="18"
     Protein         1..160
                     /product="interleukin-17C precursor"
                     /note="Interleukin 17-3"
                     /calculated_mol_wt=15843
     sig_peptide     1..21
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2521
     CDS             1..160
                     /gene="il17c"
                     /gene_synonym="il17-3"
                     /coded_by="NM_001020788.2:478..960"
                     /db_xref="GeneID:553960"
                     /db_xref="ZFIN:ZDB-GENE-061031-5"
ORIGIN      
        1 mwsplffgll ffwlseskve gkhlcfkdcd hgfskahqkl lrslisprhp pvqpvhhpag
       61 scedfvrtas ddlkhrslsp wrtrtvenpd mypskyeeaq clcdgciing elnrsynsvp
      121 vfkthvflkk hpcpsdpdky sftfehvqvp vactcavpkq
//
LOCUS       NP_001019347             950 aa            linear   VRT 18-JUN-2025
DEFINITION  protocadherin 2 gamma 3 precursor [Danio rerio].
ACCESSION   NP_001019347 XP_001340057
VERSION     NP_001019347.2
DBSOURCE    REFSEQ: accession NM_001024176.3
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 950)
  AUTHORS   Tan,Y.P., Li,S., Jiang,X.J., Loh,W., Foo,Y.K., Loh,C.B., Xu,Q.,
            Yuen,W.H., Jones,M., Fu,J., Venkatesh,B. and Yu,W.P.
  TITLE     Regulation of protocadherin gene expression by multiple
            neuron-restrictive silencer elements scattered in the gene cluster
  JOURNAL   Nucleic Acids Res 38 (15), 4985-4997 (2010)
   PUBMED   20385576
REFERENCE   2  (residues 1 to 950)
  AUTHORS   Wu,Q.
  TITLE     Comparative genomics and diversifying selection of the clustered
            vertebrate protocadherin genes
  JOURNAL   Genetics 169 (4), 2179-2188 (2005)
   PUBMED   15744052
REFERENCE   3  (residues 1 to 950)
  AUTHORS   Tada,M.N., Senzaki,K., Tai,Y., Morishita,H., Tanaka,Y.Z.,
            Murata,Y., Ishii,Y., Asakawa,S., Shimizu,N., Sugino,H. and Yagi,T.
  TITLE     Genomic organization and transcripts of the zebrafish Protocadherin
            genes
  JOURNAL   Gene 340 (2), 197-211 (2004)
   PUBMED   15475161
REFERENCE   4  (residues 1 to 950)
  AUTHORS   Noonan,J.P., Grimwood,J., Schmutz,J., Dickson,M. and Myers,R.M.
  TITLE     Gene conversion and the evolution of protocadherin gene cluster
            diversity
  JOURNAL   Genome Res 14 (3), 354-366 (2004)
   PUBMED   14993203
REFERENCE   5  (residues 1 to 950)
  AUTHORS   Zhang,T., Haws,P. and Wu,Q.
  TITLE     Multiple variable first exons: a mechanism for cell- and
            tissue-specific gene regulation
  JOURNAL   Genome Res 14 (1), 79-89 (2004)
   PUBMED   14672974
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000014.1.
            
            On Jun 18, 2025 this sequence version replaced NP_001019347.1.
FEATURES             Location/Qualifiers
     source          1..950
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="14"
                     /map="14"
     Protein         1..950
                     /product="protocadherin 2 gamma 3 precursor"
                     /note="protocadherin cluster 2 gamma 3"
                     /calculated_mol_wt=100487
     sig_peptide     1..31
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=3576
     CDS             1..950
                     /gene="pcdh2g3"
                     /coded_by="NM_001024176.3:134..2986"
                     /db_xref="GeneID:554051"
                     /db_xref="ZFIN:ZDB-GENE-050610-25"
ORIGIN      
        1 mimswafqrf cvaaemfgll ffvlmahsay gdvsysfpee mkrgsvigni akdlgldvnr
       61 lsfrkaridt egnrkrycdi nlntgeltva eridreeicg drascvlkfe fmledplelh
      121 rvslqiqdin dnspvfsndl itfeisesai rgtryrlnaa hdadvgqnav qryslqkndn
      181 fqlainsdvh geknvellle keldreqqke vtliltavdg gtpprsgtva ihvtvldand
      241 napvfsqavy kvslpenspv dtvvvtvsat dadegqngev tyafsrisdk akkmfsldkn
      301 tgdvriagal dfedeavyel rvegkdvfgl ssdakvvinl sdvndnapei rlkslrspvp
      361 esalpgtevg iinvqdrdse nngqvrcsiq qnvpfklvps iknyyslvtt geldrellse
      421 ynititatde gspplsstkn ihltvadvnd nppvfqqqny rahvqennka gssicsvsat
      481 dpdwrqngtv vysllssdvn gapvssflsi ngdtgvihav rsfdyeqmks fkvlvlardn
      541 gspplssnvt vsvfisdend nspqilypsp egnsfmtemv pkaaqarslv skviavdads
      601 gqnawlsyhi ikatdpglft igvhsgeirt qrdisesdsm kqnlivsvrd ngqpslsatc
      661 alyllvsdnl aevpelkdms hdessskltf yliialvsvs tffltfiiii lavrfcrrrk
      721 prllfdgava ipsaylppny aevegagtlr saynydaylt tgsrtsdfkf vrsyndgtlt
      781 adltlrktqs svddleglda emidsfqqkp psadwrftqn qrpgpsgaaa tpevavgtgp
      841 wpnppteaeq lqalmaaane vseatnflap gtmdlstryg pqftlqhvpd yrqnvyipgs
      901 tatltsnqqq pqqalpppqa saaiavaqpe ppkaaqtpas kkkatkkekk
//
LOCUS       NP_001307672             183 aa            linear   PRI 18-JUN-2025
DEFINITION  queuosine-tRNA galactosyltransferase isoform c [Homo sapiens].
ACCESSION   NP_001307672 XP_011521838 XP_011545064
VERSION     NP_001307672.1
DBSOURCE    REFSEQ: accession NM_001320743.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 183)
  AUTHORS   Zhao,X., Ma,D., Ishiguro,K., Saito,H., Akichika,S., Matsuzawa,I.,
            Mito,M., Irie,T., Ishibashi,K., Wakabayashi,K., Sakaguchi,Y.,
            Yokoyama,T., Mishima,Y., Shirouzu,M., Iwasaki,S., Suzuki,T. and
            Suzuki,T.
  TITLE     Glycosylated queuosines in tRNAs optimize translational rate and
            post-embryonic growth
  JOURNAL   Cell 186 (25), 5517-5535 (2023)
   PUBMED   37992713
REFERENCE   2  (residues 1 to 183)
  AUTHORS   Zheng,H., Li,Y., Ji,C., Li,J., Zhang,J., Yin,G., Xu,J., Ye,X.,
            Wu,M., Zou,X., Gu,S., Xie,Y. and Mao,Y.
  TITLE     Characterization of a cDNA encoding a protein with limited
            similarity to beta1, 3-N-acetylglucosaminyltransferase
  JOURNAL   Mol Biol Rep 31 (3), 171-175 (2004)
   PUBMED   15560372
  REMARK    GeneRIF: beta3-GnTL1 is similar to beta1,
            3-N-acetylglucosaminyltransferase
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130371.4.
            
            On or before Mar 4, 2016 this sequence version replaced
            XP_011521838.1, XP_011545064.1.
            
            Transcript Variant: This variant (3) represents the use of an
            alternate promoter and therefore differs in the 5' UTR and 5'
            coding region, compared to variant 1. These differences cause
            translation initiation at a downstream start codon and result in an
            isoform (c) with a shorter N-terminus, compared to isoform a.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.74220.1,
                                           SRR3476690.877530.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA2142348
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..183
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.3"
     Protein         1..183
                     /product="queuosine-tRNA galactosyltransferase isoform c"
                     /EC_number="2.4.1.-"
                     /note="UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 8;
                     UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase-like protein 1;
                     BGnT-like protein 1; UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase like 1;
                     beta3Gn-T-like protein 1;
                     beta1,3-N-acetylglucosaminyltransferase-like protein 1;
                     beta-1,3-Gn-T8"
                     /calculated_mol_wt=21100
     Region          <1..62
                     /region_name="Glyco_tranf_GTA_type"
                     /note="Glycosyltransferase family A (GT-A) includes
                     diverse families of glycosyl transferases with a common
                     GT-A type structural fold; cl11394"
                     /db_xref="CDD:472172"
     CDS             1..183
                     /gene="QTGAL"
                     /gene_synonym="3-Gn-T8; B3GNT8; B3GNTL1; beta-1;
                     beta3Gn-T8; beta3GnTL1; BGnT-8"
                     /coded_by="NM_001320743.2:1144..1695"
                     /note="isoform c is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS82232.1"
                     /db_xref="GeneID:146712"
                     /db_xref="HGNC:HGNC:21727"
                     /db_xref="MIM:615337"
ORIGIN      
        1 mptwfcsraw fshvgpfneg gqgvpedllf fyehlrkggg virvdqslll yrhhpqaath
       61 cvlettiwth rvrfleeqal prwaaftiwn agkqgrrlyr sltagsqrkv vafcdvdenk
      121 irkgfyched sqerpkprip ilhfraarpp fvicvkldlt ggafednlrs lhlqegqdfl
      181 hfs
//
LOCUS       NP_001336415             247 aa            linear   PRI 18-JUN-2025
DEFINITION  E3 SUMO-protein ligase NSE2 isoform 1 [Homo sapiens].
ACCESSION   NP_001336415
VERSION     NP_001336415.1
DBSOURCE    REFSEQ: accession NM_001349486.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 247)
  AUTHORS   Di Benedetto,C., Oh,J., Choudhery,Z., Shi,W., Valdes,G. and
            Betancur,P.
  TITLE     NSMCE2, a novel super-enhancer-regulated gene, is linked to poor
            prognosis and therapy resistance in breast cancer
  JOURNAL   BMC Cancer 22 (1), 1056 (2022)
   PUBMED   36224576
  REMARK    GeneRIF: NSMCE2, a novel super-enhancer-regulated gene, is linked
            to poor prognosis and therapy resistance in breast cancer.
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 247)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (residues 1 to 247)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (residues 1 to 247)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   5  (residues 1 to 247)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 247)
  AUTHORS   Potts,P.R.
  TITLE     The Yin and Yang of the MMS21-SMC5/6 SUMO ligase complex in
            homologous recombination
  JOURNAL   DNA Repair (Amst) 8 (4), 499-506 (2009)
   PUBMED   19217832
  REMARK    Review article
REFERENCE   7  (residues 1 to 247)
  AUTHORS   Taylor,E.M., Copsey,A.C., Hudson,J.J., Vidot,S. and Lehmann,A.R.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   8  (residues 1 to 247)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   9  (residues 1 to 247)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   10 (residues 1 to 247)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     Human MMS21/NSE2 is a SUMO ligase required for DNA repair
  JOURNAL   Mol Cell Biol 25 (16), 7021-7032 (2005)
   PUBMED   16055714
  REMARK    GeneRIF: the human SMC5/6 complex and the SUMO ligase activity of
            hMMS21 are required for the prevention of DNA damage-induced
            apoptosis by facilitating DNA repair in human cells
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC126366.2 and AC084083.10.
            
            Summary: This gene encodes a member of a family of E3 small
            ubiquitin-related modifier (SUMO) ligases that mediates the
            attachment of a SUMO protein to proteins involved in nuclear
            transport, transcription, chromosome segregation and DNA repair.
            The encoded protein is part of the structural maintenance of
            chromosomes (SMC) 5/6 complex which plays a key role genome
            maintenance, facilitating chromosome segregation and suppressing
            mitotic recombination. A knockout of the orthologous mouse gene is
            lethal prior to embryonic day 10.5. Naturally occurring mutations
            in this gene, that abolish the SUMO ligase activity, are associated
            with primordial dwarfism and extreme insulin resistance. [provided
            by RefSeq, Mar 2017].
            
            Transcript Variant: This variant (3) uses an alternate slice site
            in the 5' UTR compared to variant 1. Variants 1-3 encode the same
            isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038194.3553317.1,
                                           SRR18074967.3778504.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.13"
     Protein         1..247
                     /product="E3 SUMO-protein ligase NSE2 isoform 1"
                     /note="E3 SUMO-protein ligase NSE2; methyl
                     methanesulfonate sensitivity gene 21; NSE2 (MMS21)
                     homolog, SMC5-SMC6 complex SUMO ligase; non-structural
                     maintenance of chromosomes element 2 homolog; zinc finger,
                     MIZ-type containing 7; non-SMC element 2, MMS21 homolog;
                     NSMCE2/PVT1 fusion; PVT1/NSMCE2 fusion; E3 SUMO-protein
                     transferase NSE2"
                     /calculated_mol_wt=27801
     Site            1
                     /site_type="acetylation"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0007744|PubMed:20068231; propagated from
                     UniProtKB/Swiss-Prot (Q96MF7.2)"
     Site            116
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q96MF7.2)"
     Region          167..237
                     /region_name="SPL-RING_NSE2"
                     /note="SPL-RING finger found in E3 SUMO-protein ligase
                     NSE2 and similar proteins; cd16651"
                     /db_xref="CDD:438313"
     CDS             1..247
                     /gene="NSMCE2"
                     /gene_synonym="C8orf36; MMS21; NSE2; ZMIZ7"
                     /coded_by="NM_001349486.2:247..990"
                     /note="isoform 1 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS6356.1"
                     /db_xref="GeneID:286053"
                     /db_xref="HGNC:HGNC:26513"
                     /db_xref="MIM:617246"
ORIGIN      
        1 mpgrsssnsg stgfisfsgv esalsslknf qacinsgmdt assvaldlve sqtevsseys
       61 mdkamvefat ldrqlnhyvk avqstinhvk eerpekipdl kllvekkfla lqsknsdadf
      121 qnnekfvqfk qqlkelkkqc glqadreadg tegvdediiv tqsqtnftcp itkeemkkpv
      181 knkvcghtye edaivrmies rqkrkkkayc pqigcshtdi rksdliqdea lrraienhnk
      241 krhrhse
//
LOCUS       NP_001380340             320 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA:m(4)X modification enzyme TRM13 homolog isoform 4 [Homo
            sapiens].
ACCESSION   NP_001380340 XP_016856993
VERSION     NP_001380340.1
DBSOURCE    REFSEQ: accession NM_001393411.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 320)
  AUTHORS   Li,H., Dong,H., Xu,B., Xiong,Q.P., Li,C.T., Yang,W.Q., Li,J.,
            Huang,Z.X., Zeng,Q.Y., Wang,E.D. and Liu,R.J.
  TITLE     A dual role of human tRNA methyltransferase hTrmt13 in regulating
            translation and transcription
  JOURNAL   EMBO J 41 (6), e108544 (2022)
   PUBMED   34850409
  REMARK    GeneRIF: A dual role of human tRNA methyltransferase hTrmt13 in
            regulating translation and transcription.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445928.8.
            
            On Feb 9, 2021 this sequence version replaced XP_016856993.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.138573.1,
                                           SRR1803615.116279.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p21.2"
     Protein         1..320
                     /product="tRNA:m(4)X modification enzyme TRM13 homolog
                     isoform 4"
                     /EC_number="2.1.1.225"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM13
                     homolog; tRNA [Gm4] methyltransferase; coiled-coil
                     domain-containing protein 76; tRNA methyltransferase 13
                     homolog; coiled-coil domain containing 76; tRNA:m(4)X
                     modification enzyme TRM13 homolog"
                     /calculated_mol_wt=35432
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0007744|PubMed:19413330,
                     ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:22223895;
                     propagated from UniProtKB/Swiss-Prot (Q9NUP7.2)"
     Region          17..45
                     /region_name="zf-TRM13_CCCH"
                     /note="CCCH zinc finger in TRM13 protein; pfam11722"
                     /db_xref="CDD:463331"
     Region          56..80
                     /region_name="zf-U11-48K"
                     /note="U11-48K-like CHHC zinc finger; pfam05253"
                     /db_xref="CDD:461603"
     Region          <99..>153
                     /region_name="DUF2764"
                     /note="Protein of unknown function (DUF2764); cl46831"
                     /db_xref="CDD:481171"
     Region          165..>273
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     CDS             1..320
                     /gene="TRMT13"
                     /gene_synonym="CCDC76; hTrmt13"
                     /coded_by="NM_001393411.1:7..969"
                     /note="isoform 4 is encoded by transcript variant 4"
                     /db_xref="GeneID:54482"
                     /db_xref="HGNC:HGNC:25502"
ORIGIN      
        1 matsatspha pgfpaegrcg yyvekkkrfc rmvvaagkrf cgehagaaee edarkrilcp
       61 ldpkhtvyed qlakhlkkcn srekpkpdfy iqdinaglrd eteipeqlvp isslseeqle
      121 klikklrkas eglnstlkdh imshpalhda lndpkngdsa tkhlkqqasi lgnienlkll
      181 gprrcfvefg agkgklshwv dialkdaekv hfilvekvtt rfkvdgkhrk knsvferlqi
      241 diqhlclnki pvlreeklpv vgigkhlcgm atdgvslcrp dwsavaqsrl tatsasrlqa
      301 illpqppell glqtrattpg
//
LOCUS       NP_001374149             526 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein Helios isoform 1 [Homo sapiens].
ACCESSION   NP_001374149
VERSION     NP_001374149.1
DBSOURCE    REFSEQ: accession NM_001387220.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 526)
  AUTHORS   Velde,H.M., Vaseghi-Shanjani,M., Smits,J.J., Ramakrishnan,G.,
            Oostrik,J., Wesdorp,M., Astuti,G., Yntema,H.G., Hoefsloot,L.,
            Lanting,C.P., Huynen,M.A., Lehman,A., Turvey,S.E., Pennings,R.J.E.
            and Kremer,H.
  CONSRTM   DOOFNL Consortium
  TITLE     Exome variant prioritization in a large cohort of hearing-impaired
            individuals indicates IKZF2 to be associated with non-syndromic
            hearing loss and guides future research of unsolved cases
  JOURNAL   Hum Genet 143 (11), 1379-1399 (2024)
   PUBMED   39406892
REFERENCE   2  (residues 1 to 526)
  AUTHORS   Lukasik,M., Telec,M., Kazmierski,R., Wojtasz,I.,
            Andrzejewska-Gorczynska,N., Kociemba,W., Dworacki,G., Kozubski,W.P.
            and Frydrychowicz,M.
  TITLE     Temporal changes in regulatory T cell subsets defined by the
            transcription factor Helios in stroke and their potential role in
            stroke-associated infection: a prospective case-control study
  JOURNAL   J Neuroinflammation 20 (1), 275 (2023)
   PUBMED   37996909
  REMARK    GeneRIF: Temporal changes in regulatory T cell subsets defined by
            the transcription factor Helios in stroke and their potential role
            in stroke-associated infection: a prospective case-control study.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 526)
  AUTHORS   Mohajeri,A., Vaseghi-Shanjani,M., Rosenfeld,J.A., Yang,G.X., Lu,H.,
            Sharma,M., Lin,S., Salman,A., Waqas,M., Sababi Azamian,M.,
            Worley,K.C., Del Bel,K.L., Kozak,F.K., Rahmanian,R., Biggs,C.M.,
            Hildebrand,K.J., Lalani,S.R., Nicholas,S.K., Scott,D.A.,
            Mostafavi,S., van Karnebeek,C., Henkelman,E., Halparin,J.,
            Yang,C.L., Armstrong,L., Turvey,S.E. and Lehman,A.
  CONSRTM   Undiagnosed Diseases Network; Care4Rare Canada Consortium
  TITLE     Dominant negative variants in IKZF2 cause ICHAD syndrome, a new
            disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay
  JOURNAL   J Med Genet 60 (11), 1092-1104 (2023)
   PUBMED   37316189
  REMARK    GeneRIF: Dominant negative variants in IKZF2 cause ICHAD syndrome,
            a new disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay.
REFERENCE   4  (residues 1 to 526)
  AUTHORS   Tarighi,M., Shahbazi,M., Saadat,P., Daraei,A., Alizadeh Khatir,A.,
            Rahimifard,K. and Mohammadnia-Afrouzi,M.
  TITLE     Decreased frequency of regulatory T cells and level of helios gene
            expression in secondary progressive multiple sclerosis patients:
            Evidence about the development of multiple sclerosis
  JOURNAL   Int Immunopharmacol 116, 109797 (2023)
   PUBMED   36738680
  REMARK    GeneRIF: Decreased frequency of regulatory T cells and level of
            helios gene expression in secondary progressive multiple sclerosis
            patients: Evidence about the development of multiple sclerosis.
REFERENCE   5  (residues 1 to 526)
  AUTHORS   Zhang,H., Jadhav,R.R., Cao,W., Goronzy,I.N., Zhao,T.V., Jin,J.,
            Ohtsuki,S., Hu,Z., Morales,J., Greenleaf,W.J., Weyand,C.M. and
            Goronzy,J.J.
  TITLE     Aging-associated HELIOS deficiency in naive CD4+ T cells alters
            chromatin remodeling and promotes effector cell responses
  JOURNAL   Nat Immunol 24 (1), 96-109 (2023)
   PUBMED   36510022
  REMARK    GeneRIF: Aging-associated HELIOS deficiency in naive CD4[+] T cells
            alters chromatin remodeling and promotes effector cell responses.
REFERENCE   6  (residues 1 to 526)
  AUTHORS   Nakase,K., Ishimaru,F., Fujii,K., Tabayashi,T., Kozuka,T.,
            Sezaki,N., Matsuo,Y. and Harada,M.
  TITLE     Overexpression of novel short isoforms of Helios in a patient with
            T-cell acute lymphoblastic leukemia
  JOURNAL   Exp Hematol 30 (4), 313-317 (2002)
   PUBMED   11937265
  REMARK    GeneRIF: Novel short isoforms of Helios are overexpressed in a
            patient with T-cell acute lymphoblastic leukemia and may contribute
            to the development of T-cell malignancies. Data for unaltered
            Helios indicates tumor suppressor function.
REFERENCE   7  (residues 1 to 526)
  AUTHORS   Perdomo,J., Holmes,M., Chong,B. and Crossley,M.
  TITLE     Eos and pegasus, two members of the Ikaros family of proteins with
            distinct DNA binding activities
  JOURNAL   J Biol Chem 275 (49), 38347-38354 (2000)
   PUBMED   10978333
REFERENCE   8  (residues 1 to 526)
  AUTHORS   Hosokawa,Y., Maeda,Y. and Seto,M.
  TITLE     Human Helios, an Ikaros-related zinc finger DNA binding protein:
            cDNA cloning and tissue expression pattern
  JOURNAL   Immunogenetics 50 (1-2), 106-108 (1999)
   PUBMED   10541817
REFERENCE   9  (residues 1 to 526)
  AUTHORS   Kelley,C.M., Ikeda,T., Koipally,J., Avitahl,N., Wu,L.,
            Georgopoulos,K. and Morgan,B.A.
  TITLE     Helios, a novel dimerization partner of Ikaros expressed in the
            earliest hematopoietic progenitors
  JOURNAL   Curr Biol 8 (9), 508-515 (1998)
   PUBMED   9560339
REFERENCE   10 (residues 1 to 526)
  AUTHORS   Hahm,K., Cobb,B.S., McCarty,A.S., Brown,K.E., Klug,C.A., Lee,R.,
            Akashi,K., Weissman,I.L., Fisher,A.G. and Smale,S.T.
  TITLE     Helios, a T cell-restricted Ikaros family member that
            quantitatively associates with Ikaros at centromeric
            heterochromatin
  JOURNAL   Genes Dev 12 (6), 782-796 (1998)
   PUBMED   9512513
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC079610.4, AC013736.9 and
            AC108066.3.
            
            Summary: This gene encodes a member of the Ikaros family of
            zinc-finger proteins. Three members of this protein family (Ikaros,
            Aiolos and Helios) are hematopoietic-specific transcription factors
            involved in the regulation of lymphocyte development. This protein
            forms homo- or hetero-dimers with other Ikaros family members, and
            is thought to function predominantly in early hematopoietic
            development. Multiple transcript variants encoding different
            isoforms have been found for this gene, but the biological validity
            of some variants has not been determined. [provided by RefSeq, Jul
            2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038194.3599081.1,
                                           SRR14038192.2525778.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000434687.6/ ENSP00000412869.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..526
                     /product="zinc finger protein Helios isoform 1"
                     /note="zinc finger protein, subfamily 1A, 2 (Helios); zinc
                     finger DNA binding protein Helios; zinc finger protein
                     Helios; ikaros family zinc finger protein 2"
                     /calculated_mol_wt=59443
     Region          28..91
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            56
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            78
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            79
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Region          114..134
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(119,121,123,125..126,129..130,133,147,149,153..154,
                     157..158,161,175,177,179,181..182,185..186,189)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          127..151
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          142..162
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          154..179
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          170..190
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          186..207
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          198..219
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            288
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:19608861; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Region          370..435
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKS7.2)"
     CDS             1..526
                     /gene="IKZF2"
                     /gene_synonym="ANF1A2; HELIOS; ICHAD; IMDIA; ZNF1A2;
                     ZNFN1A2"
                     /coded_by="NM_001387220.1:320..1900"
                     /note="isoform 1 is encoded by transcript variant 7"
                     /db_xref="CCDS:CCDS2395.1"
                     /db_xref="GeneID:22807"
                     /db_xref="HGNC:HGNC:13177"
                     /db_xref="MIM:606234"
ORIGIN      
        1 meteaidgyi tcdnelsper ehsnmaidlt sstpngqhas pshmtstnsv klemqsdeec
       61 drkplsrede irghdegssl eepliessev adnrkvqelq geggirlpng klkcdvcgmv
      121 cigpnvlmvh krshtgerpf hcnqcgasft qkgnllrhik lhsgekpfkc pfcsyacrrr
      181 daltghlrth svgkphkcny cgrsykqrss leehkerchn ylqnvsmeaa gqvmshhvpp
      241 medckeqepi mdnnislvpf erpavieklt gnmgkrksst pqkfvgeklm rfsypdihfd
      301 mnltyekeae lmqshmmdqa innaitylga ealhplmqhp pstiaevapv issaysqvyh
      361 pnrierpisr etadshennm dgpislirpk srpqereasp snscldstds esshddhqsy
      421 qghpalnpkr kqspaymked vkaldttkap kgslkdiykv fngegeqira fkcehcrvlf
      481 ldhvmytihm gchgyrdple cnicgyrsqd ryefsshivr gehtfh
//
LOCUS       NP_001266727             314 aa            linear   VRT 18-JUN-2025
DEFINITION  hydroxysteroid (20-beta) dehydrogenase 2 [Oreochromis niloticus].
ACCESSION   NP_001266727 XP_003456861
VERSION     NP_001266727.1
DBSOURCE    REFSEQ: accession NM_001279798.2
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 314)
  AUTHORS   Tokarz,J., Mindnich,R., Norton,W., Moller,G., Hrabe de Angelis,M.
            and Adamski,J.
  TITLE     Discovery of a novel enzyme mediating glucocorticoid catabolism in
            fish: 20beta-hydroxysteroid dehydrogenase type 2
  JOURNAL   Mol Cell Endocrinol 349 (2), 202-213 (2012)
   PUBMED   22061621
REFERENCE   2  (residues 1 to 314)
  AUTHORS   Zhou,L.Y., Wang,D.S., Senthilkumaran,B., Yoshikuni,M., Shibata,Y.,
            Kobayashi,T., Sudhakumari,C.C. and Nagahama,Y.
  TITLE     Cloning, expression and characterization of three types of
            17beta-hydroxysteroid dehydrogenases from the Nile tilapia,
            Oreochromis niloticus
  JOURNAL   J Mol Endocrinol 35 (1), 103-116 (2005)
   PUBMED   16087725
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            MKQE02000010.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003456861.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY663854.2, GBAR01100435.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767854 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG10"
                     /linkage_group="LG10"
     Protein         1..314
                     /product="hydroxysteroid (20-beta) dehydrogenase 2"
                     /note="20beta-hydroxysteroid dehydrogenase type 2; 17-beta
                     hydroxysteroid dehydrogenase type 12"
                     /calculated_mol_wt=34719
     Region          <5..>79
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Region          47..281
                     /region_name="17beta-HSD1_like_SDR_c"
                     /note="17-beta-hydroxysteroid dehydrogenases (17beta-HSDs)
                     types -1, -3, and -12, -like, classical (c) SDRs; cd05356"
                     /db_xref="CDD:187614"
     Site            order(54,56..59,78..80,103..105,131..133,159,186..188,201,
                     205,231..234,236..237)
                     /site_type="other"
                     /note="putative NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187614"
     Site            order(160,188,201,205)
                     /site_type="active"
                     /db_xref="CDD:187614"
     CDS             1..314
                     /gene="hsd20b2"
                     /gene_synonym="hsd17b12"
                     /coded_by="NM_001279798.2:93..1037"
                     /db_xref="GeneID:100534526"
ORIGIN      
        1 msfadllaii ggmtvafyll kltwrcwcvf refvlsskwq vdlrtygqwa vvtgatsgig
       61 kayatelarr gldivlisrc dnklktvare iegvygrktq tipvdfthgy siypaiakkl
      121 qglqigilvn nvgmtttdcf ayfletpdae qkitqvincn ilsvpqmtrl vlpdmvkrgk
      181 gliinissmt gvhpqplltl ysatktfvty fsqclhaeyk skgitvqcva pflvstnmtk
      241 nvkvnsfmks atafarealn tvghsscttg clshavqnal ltillpdrlr mstflirklr
      301 ssckkndwtg ekge
//
LOCUS       NP_001333845             610 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein 429 isoform d [Homo sapiens].
ACCESSION   NP_001333845 XP_016882246
VERSION     NP_001333845.1
DBSOURCE    REFSEQ: accession NM_001346916.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 610)
  AUTHORS   Kim,H., Ramsay,E., Lee,H., Wahl,S. and Dionne,R.A.
  TITLE     Genome-wide association study of acute post-surgical pain in humans
  JOURNAL   Pharmacogenomics 10 (2), 171-179 (2009)
   PUBMED   19207018
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   2  (residues 1 to 610)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010615.9.
            
            On Nov 8, 2016 this sequence version replaced XP_016882246.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.26806.1,
                                           SRR1660805.89784.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968832, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     Protein         1..610
                     /product="zinc finger protein 429 isoform d"
                     /calculated_mol_wt=70629
     Region          83..103
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          111..131
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          139..159
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          165..560
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          167..187
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          195..215
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          223..243
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          251..271
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(256,258,260,262..263,266..267,270,284,286,290..291,
                     294..295,298,312,314,316,318..319,322..323,326)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          279..299
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          307..327
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          338..355
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          363..383
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(368,370,372,374..375,378..379,382,396,398,402..403,
                     406..407,410,424,426,428,430..431,434..435,438)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          391..411
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          419..439
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          447..467
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          475..495
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(480,482,484,486..487,490..491,494,508,510,514..515,
                     518..519,522,536,538,540,542..543,546..547,550)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          503..523
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          531..551
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          559..579
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..610
                     /gene="ZNF429"
                     /coded_by="NM_001346916.2:236..2068"
                     /note="isoform d is encoded by transcript variant 6"
                     /db_xref="GeneID:353088"
                     /db_xref="HGNC:HGNC:20817"
                     /db_xref="MIM:621242"
ORIGIN      
        1 mkrhemvdep pvvcshfaed fwpeqdikds fqkvtlrryd krghenlqlr kgyktvgdck
       61 lykggyngln qcltltqskm yhcdiyvkvf yafsnadryk trhtgkkpfq ckkcgksfcm
      121 lsqltqhkki hirentyrck efgnafnqss altnhkriyv gekhyrceec gkafnhystl
      181 tnhkrihtge kpykckecgk afsrystltt hkrihsgekp ykcdecgktf sisstftkhk
      241 iihteekpyk ckecgkafnr sstltshkri htgekpykce ecgkafnwss tltkhkviht
      301 gekpykceec gkafnqssrl trhkkihtge epykfekcgr vftcsstltq dkkihtgekp
      361 ynceecgkvf tysstltrhk rihteekpyk cnecgkafnr sshltshrri htgekpykce
      421 ecgkafkqss nlnshkkihs gekpykceec gkafilssrl tqhkkihtge kpykceecgk
      481 afnrssrltq hkkihtgekp ykckqcdkaf thssnlsshk kihsgekpyk ceecgkafnr
      541 ssrltqhkki htrekpykce ecakaftrss rltqhkkihr mgvvahacnp stlggrggri
      601 trsgdrdrpg
//
LOCUS       NP_001380338             467 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA:m(4)X modification enzyme TRM13 homolog isoform 2 [Homo
            sapiens].
ACCESSION   NP_001380338 XP_005271002
VERSION     NP_001380338.1
DBSOURCE    REFSEQ: accession NM_001393409.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 467)
  AUTHORS   Li,H., Dong,H., Xu,B., Xiong,Q.P., Li,C.T., Yang,W.Q., Li,J.,
            Huang,Z.X., Zeng,Q.Y., Wang,E.D. and Liu,R.J.
  TITLE     A dual role of human tRNA methyltransferase hTrmt13 in regulating
            translation and transcription
  JOURNAL   EMBO J 41 (6), e108544 (2022)
   PUBMED   34850409
  REMARK    GeneRIF: A dual role of human tRNA methyltransferase hTrmt13 in
            regulating translation and transcription.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445928.8.
            
            On Feb 9, 2021 this sequence version replaced XP_005271002.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DRR138517.886588.1,
                                           SRR1803615.64118.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p21.2"
     Protein         1..467
                     /product="tRNA:m(4)X modification enzyme TRM13 homolog
                     isoform 2"
                     /EC_number="2.1.1.225"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM13
                     homolog; tRNA [Gm4] methyltransferase; coiled-coil
                     domain-containing protein 76; tRNA methyltransferase 13
                     homolog; coiled-coil domain containing 76; tRNA:m(4)X
                     modification enzyme TRM13 homolog"
                     /calculated_mol_wt=52584
     Region          17..45
                     /region_name="zf-TRM13_CCCH"
                     /note="CCCH zinc finger in TRM13 protein; pfam11722"
                     /db_xref="CDD:463331"
     Region          56..80
                     /region_name="zf-U11-48K"
                     /note="U11-48K-like CHHC zinc finger; pfam05253"
                     /db_xref="CDD:461603"
     Region          151..455
                     /region_name="TRM13"
                     /note="Methyltransferase TRM13; pfam05206"
                     /db_xref="CDD:398743"
     CDS             1..467
                     /gene="TRMT13"
                     /gene_synonym="CCDC76; hTrmt13"
                     /coded_by="NM_001393409.1:7..1410"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:54482"
                     /db_xref="HGNC:HGNC:25502"
ORIGIN      
        1 matsatspha pgfpaegrcg yyvekkkrfc rmvvaagkrf cgehagaaee edarkrilcp
       61 ldpkhtvyed qlakhlkkcn srekpkpdfy iqdinaglrd eteipeqlvp isslseeqle
      121 klikklrkas ealhdalndp kngdsatkhl kqqasilgni enlkllgprr cfvefgagkg
      181 klshwvdial kdaekvhfil vekvttrfkv dgkhrkknsv ferlqidiqh lclnkipvlr
      241 eeklpvvgig khlcgmatdl alrclvetya asfeerneep lakrikndkt ekeiytlake
      301 gneknvpekw npvagivial cchhrcdwrh yvgkeyfral glgavefhyf qrmsswatcg
      361 mrktsletsn sttkrqdnqn ddseehddgg yritddgadc lpgllsveek kkighlckll
      421 idqgriqylq qkgfspalqy ytdplvslen vlltalpnhs sspetta
//
LOCUS       NP_001337512             400 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform c [Homo
            sapiens].
ACCESSION   NP_001337512
VERSION     NP_001337512.1
DBSOURCE    REFSEQ: accession NM_001350583.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 400)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 400)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 400)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 400)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 400)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 400)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 400)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 400)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 400)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 400)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (5), as well as variants 3, 4, and
            6, encodes isoform c.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038192.1887770.1,
                                           SRR1660809.190224.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2149876, SAMEA2152568
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..400
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform c"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=46106
     Region          134..323
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..400
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350583.2:316..1518"
                     /note="isoform c is encoded by transcript variant 5"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mkrtvcaksi felwghgqsp eelysslkny pvekmvpflh sdstykikih tfnktltqee
       61 kikridalef lpfegkvnlk kpqhvfsvle dygldpncip enphniyfgr wiadgqreli
      121 esysvkkrhf igntsmdagl sfimanhgkv kendivfdpf vgtgglliac ahfgayvygt
      181 didyntvhgl gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask pswrkgtyfd
      241 aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf ldllnfaaet
      301 lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm ekvkkfenrd
      361 qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001276565             512 aa            linear   VRT 18-JUN-2025
DEFINITION  peroxisome proliferator-activated receptor delta b [Oreochromis
            niloticus].
ACCESSION   NP_001276565 XP_003448192
VERSION     NP_001276565.1
DBSOURCE    REFSEQ: accession NM_001289636.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KF751705.1.
            
            On Jan 24, 2014 this sequence version replaced XP_003448192.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KF751705.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2482241, SAMEA2482243
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG20"
                     /linkage_group="LG20"
     Protein         1..512
                     /product="peroxisome proliferator-activated receptor delta
                     b"
                     /note="PPAR beta; peroxisome proliferator-activated
                     receptor beta; peroxisome proliferator activated receptor
                     delta"
                     /calculated_mol_wt=57439
     Region          144..227
                     /region_name="NR_DBD_Ppar"
                     /note="DNA-binding domain of peroxisome
                     proliferator-activated receptors (PPAR) is composed of two
                     C4-type zinc fingers; cd06965"
                     /db_xref="CDD:143523"
     Site            order(145,148,162,165,181,186,196,199)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:143523"
     Site            order(153..157,163..164,166,168,170..171,174,193..194,197,
                     200,211,214..218,220)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143523"
     Site            order(191..192,194..195)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:143523"
     Region          244..511
                     /region_name="NR_LBD_PPAR"
                     /note="The ligand binding domain of peroxisome
                     proliferator-activated receptors; cd06932"
                     /db_xref="CDD:132730"
     Site            order(319..320,324,358,362,365,374,376,399,484)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:132730"
     Site            order(329,332,336,341,346..347,349..350,353..354)
                     /site_type="other"
                     /note="coactivator recognition site [polypeptide binding]"
                     /db_xref="CDD:132730"
     Site            order(408,430,433,442,465,469,472,474..475,478..479,486)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:132730"
     CDS             1..512
                     /gene="ppardb"
                     /gene_synonym="ppard"
                     /coded_by="NM_001289636.1:358..1896"
                     /db_xref="GeneID:100534460"
ORIGIN      
        1 mdgfqqtape khdgvngyce pnspqdaadv rwtppqaesv gsdscgatsv sevadlkelk
       61 rresedeeek eekeekegvp askypkrdqk krrkegedqe nsdnkqnssa sssytdlsht
      121 sspslseqlr lgredstssg isveckvcgd kasgfhygvh acegckgffr rtvrmkleye
      181 rcersckiqk knrnkcqycr fqkclslgms hdairygrmp eaerkklvag ilaeelnvsk
      241 pggsdlktla kqvntayqkn lsmtkkrars ilmgktssts pfviydvdtl wkaesglvws
      301 qltpgapltk eigvhvfyrc qcttvetvre ltefakcipg fvdlflndqv tllkygvhea
      361 ifamlpslmn kdgllvangk gfvtreflrs lrkpfseime pkfefavkfn alelddsdla
      421 lfvaaiilcg drpglmnvkq veqsqdnilq aldlhlqanh sdsaylfpkl lqkmadlrql
      481 vtenaqlvqk ikktesetsl hpllqeiykd my
//
LOCUS       NP_001266407             864 aa            linear   VRT 18-JUN-2025
DEFINITION  glutamate receptor 2b precursor [Oreochromis niloticus].
ACCESSION   NP_001266407 XP_003443499 XP_003443500 XP_003443501
VERSION     NP_001266407.1
DBSOURCE    REFSEQ: accession NM_001279478.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 864)
  AUTHORS   Kung,S.S., Wu,Y.M. and Chow,W.Y.
  TITLE     Characterization of two fish glutamate receptor cDNA molecules:
            absence of RNA editing at the Q/R site
  JOURNAL   Brain Res Mol Brain Res 35 (1-2), 119-130 (1996)
   PUBMED   8717347
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from L37836.1.
            
            On or before Jul 22, 2013 this sequence version replaced
            XP_003443499.1, XP_003443500.1, XP_003443501.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L37836.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2482242, SAMEA2482243
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..864
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG2"
                     /linkage_group="LG2"
     Protein         1..864
                     /product="glutamate receptor 2b precursor"
                     /note="glutamate receptor subunit 2B; glutamate receptor
                     B; glutamate ionotropic receptor AMPA type subunit 2"
                     /calculated_mol_wt=95785
     sig_peptide     1..15
                     /calculated_mol_wt=1768
     Region          15..382
                     /region_name="Periplasmic_Binding_Protein_type1"
                     /note="Type 1 periplasmic binding fold superfamily;
                     cl10011"
                     /db_xref="CDD:471960"
     mat_peptide     16..864
                     /product="glutamate receptor 2b"
                     /calculated_mol_wt=95785
     Region          395..775
                     /region_name="PBP2_iGluR_AMPA"
                     /note="The ligand-binding domain of the AMPA
                     (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic
                     acid) subtypes of ionotropic glutamate receptors, a member
                     of the type 2 periplasmic binding fold protein
                     superfamily; cd13715"
                     /db_xref="CDD:270433"
     Site            order(434,438,485..486,489,494..497,731,749..750,753..758,
                     760,763)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:270433"
     Site            order(453,481..483,488,652,655..657,706..707,710,734)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:270433"
     Site            order(496..500,753,756,761..762,765)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:270433"
     CDS             1..864
                     /gene="gria2b"
                     /gene_synonym="glur2b; gria2"
                     /coded_by="NM_001279478.1:354..2948"
                     /db_xref="GeneID:100534557"
ORIGIN      
        1 mgmrawrlaq csdwgtyprr adqeysafri gmvqfgtsef rltphidnle vansfavtnc
       61 fcsqfsrgvy aifgfydkks vntitsfcgt lhvsfitpsf pldgshqfii qmrpdikgpl
      121 lslieyykwd kfaylydsdr glttlqivld taaekkwqvt ainvgnlkde rkdeayrslf
      181 qdlenkkhrr vildceqdkv kdimeqviti grhvkgyhyi ianlgfidgd lskiqyggan
      241 vsgfqivdfd dplvskfdqr wealeekeyp gadskiryts altydavqvm teafrylhkq
      301 ridftrrant gdclanpavp waqgveiera lkqvrveglt gniqfdqhgk rvnysvnime
      361 lksngpvkig ywnemhkmav tksdvftndt tgmenktviv ttileapyvm lkknadlfvd
      421 neryegncvd laaeiakhcg fkyqlkivgd gkygardaet kiwngmvgef vygkadiava
      481 pltitlvree vidfskpfms lgisimikkp qkskpgvfsf ldplayeiwm civfayigvs
      541 vvlflvsrfs ayewhteeye dgqiqtnest nefgifnslw fslgafmrqg cdisprslsg
      601 rivggvwwff tliiissyta nlaafltver mvspiesaed lakqteiayg tldsgstkef
      661 frrskialfd kmwtymrgae psvfvkttae gvqrvrkskg kyayllestm neyieqrkpc
      721 dtmkvggnld skgygiatpk gsslrnavnl avlklneqgl ldklknkwwy dkgecgsggg
      781 dskektsals lsnvagvfyi lvgglglaml valiefcyks raeakrmkva knaqninpts
      841 sqnsqnfaty kegynvygie svki
//
LOCUS       NP_001337519             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337519
VERSION     NP_001337519.1
DBSOURCE    REFSEQ: accession NM_001350590.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (12), as well as variants 8-11 and
            13-19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.1940856.1,
                                           SRR1803612.40768.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2158188, SAMN04284274
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350590.2:1390..2082"
                     /note="isoform e is encoded by transcript variant 12"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001266666            1172 aa            linear   VRT 18-JUN-2025
DEFINITION  thrombospondin-1b precursor [Oreochromis niloticus].
ACCESSION   NP_001266666 XP_003447783
VERSION     NP_001266666.1
DBSOURCE    REFSEQ: accession NM_001279737.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 1172)
  AUTHORS   Wu,F.R., Zhou,L.Y., Nagahama,Y. and Wang,D.S.
  TITLE     Duplication and distinct expression patterns of two
            thrombospondin-1 isoforms in teleost fishes
  JOURNAL   Gene Expr Patterns 9 (6), 436-443 (2009)
   PUBMED   19501195
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from FJ455497.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003447783.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FJ455497.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1172
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG19"
                     /linkage_group="LG19"
     Protein         1..1172
                     /product="thrombospondin-1b precursor"
                     /note="thrombospondin-1b"
                     /calculated_mol_wt=127982
     sig_peptide     1..17
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=1961
     Region          25..220
                     /region_name="LamG"
                     /note="Laminin G domain; Laminin G-like domains are
                     usually Ca++ mediated receptors that can have binding
                     sites for steroids, beta1 integrins, heparin, sulfatides,
                     fibulin-1, and alpha-dystroglycans. Proteins that contain
                     LamG domains serve a variety of...; cl22861"
                     /db_xref="CDD:473984"
     Region          319..372
                     /region_name="VWC"
                     /note="von Willebrand factor type C domain; pfam00093"
                     /db_xref="CDD:278520"
     Region          384..431
                     /region_name="TSP1"
                     /note="Thrombospondin type 1 repeats; smart00209"
                     /db_xref="CDD:214559"
     Region          440..492
                     /region_name="TSP1"
                     /note="Thrombospondin type 1 repeats; smart00209"
                     /db_xref="CDD:214559"
     Region          497..549
                     /region_name="TSP1"
                     /note="Thrombospondin type 1 repeats; smart00209"
                     /db_xref="CDD:214559"
     Region          652..691
                     /region_name="EGF_3"
                     /note="EGF domain; pfam12947"
                     /db_xref="CDD:463759"
     Region          693..728
                     /region_name="TSP3 repeat_1C"
                     /note="TSP3 repeat_1C [structural motif]"
                     /db_xref="CDD:275367"
     Region          729..764
                     /region_name="TSP3 repeat_long"
                     /note="TSP3 repeat_long [structural motif]"
                     /db_xref="CDD:275366"
     Region          765..787
                     /region_name="TSP3 repeat_short"
                     /note="TSP3 repeat_short [structural motif]"
                     /db_xref="CDD:275365"
     Region          788..823
                     /region_name="TSP_3"
                     /note="Thrombospondin type 3 repeat; pfam02412"
                     /db_xref="CDD:367074"
     Region          789..823
                     /region_name="TSP3 repeat_long"
                     /note="TSP3 repeat_long [structural motif]"
                     /db_xref="CDD:275366"
     Region          824..846
                     /region_name="TSP3 repeat_short"
                     /note="TSP3 repeat_short [structural motif]"
                     /db_xref="CDD:275366"
     Region          847..884
                     /region_name="TSP3 repeat_long"
                     /note="TSP3 repeat_long [structural motif]"
                     /db_xref="CDD:275365"
     Region          848..884
                     /region_name="TSP_3"
                     /note="Thrombospondin type 3 repeat; pfam02412"
                     /db_xref="CDD:367074"
     Region          885..920
                     /region_name="TSP3 repeat_short"
                     /note="TSP3 repeat_short [structural motif]"
                     /db_xref="CDD:275366"
     Region          922..951
                     /region_name="TSP_3"
                     /note="Thrombospondin type 3 repeat; pfam02412"
                     /db_xref="CDD:367074"
     Region          974..1171
                     /region_name="TSP_C"
                     /note="Thrombospondin C-terminal region; pfam05735"
                     /db_xref="CDD:461725"
     CDS             1..1172
                     /gene="thbs1a"
                     /coded_by="NM_001279737.1:1..3519"
                     /db_xref="GeneID:100533982"
ORIGIN      
        1 mmlcgiflll mlwscegarl aesrddnsvy dlfelarvnk rhhgvsmvkg qdpyspaykv
       61 lnanlippvp dssfrdllds iqtergflll vnlkqfkktr gslltvektd gsgpifeiis
      121 ngkantldlv ystvdqqqvv sidevdlatg qwknitlfvq ddraqlfvgc eeisdselev
      181 piqkvfsqev adtarlrigk galkdkffgv lqnvrfvfgt tldailrnkg cqtgaaltdv
      241 mtldnpvngs spairtdytg hkakdlqsvc gfscedianm fnelkglntv vrqlskelqr
      301 vaeesssiin ymnlrkgvci hngimrqdrd ewtvdsctec tcqnsatvcr kitcplipca
      361 natvpdgecc prrgtpsdya edgwsawsew tqcsvtcgrg iqqrgrscdr inskcegtsv
      421 qtrdcypqec dkrfkqdggw shwspwsscs vacgegvmtq irlcnsptpq mggkdcegeg
      481 rhtkvcrksp cpinggwgpw spwdtcsvtc gggvqtrkrl csdpapkygg kdcigdases
      541 qicnkqecpi dgclsspcfp gtkctsfrdg sfkcgrcpsg ytgngitckd ideckevpda
      601 chthngvhrc entepgyncl pcpprfsgpq pfgrgvaeat akkqvcvprn pckdgshnch
      661 knanciylgv fsesmfrcec kpgyagngri cgedsdldgw pntdllcven atyhckkdnc
      721 pylpnsgqed hdkdglgdec dhdddndgip ddrdncprvy npaqydadrd dvgdscdncv
      781 hvantdqtdt dnngegdaca vdidgdgiln endncpyvyn vdqrdtdrdg vgdhcdncpl
      841 ehnpdqidsd sdrvgdkcdn nqdidedghq nnldncpyip nanqadhdkd gkgdacdhdd
      901 dndgipddkd ncrlafnpdq vdsdgdgrgd vckddfdqdn vldihdvcpe nfaisetdfr
      961 rfqmvpldpk gtsqidpnwv vrhqgkelvq tvncdpgiav gydefsavdf sgtffintdr
     1021 dddyagfvfg yqsssrfytv mwkqitqtyw sntptraqgy sglsikvvns ttgpgehlrn
     1081 alwhtgdtpg qvrtlwhdpk nigwkdftay rwhlthrpkt glirvvmyeg krimadsgni
     1141 ydktyaggrl glyvfsqemv yfsdlkyecr dt
//
LOCUS       NP_001337526             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337526
VERSION     NP_001337526.1
DBSOURCE    REFSEQ: accession NM_001350597.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (19), as well as variants 8-18,
            encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074968.728671.1,
                                           SRR14038192.3040643.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350597.2:1303..1995"
                     /note="isoform e is encoded by transcript variant 19"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001333841             672 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein 429 isoform b [Homo sapiens].
ACCESSION   NP_001333841
VERSION     NP_001333841.1
DBSOURCE    REFSEQ: accession NM_001346912.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 672)
  AUTHORS   Kim,H., Ramsay,E., Lee,H., Wahl,S. and Dionne,R.A.
  TITLE     Genome-wide association study of acute post-surgical pain in humans
  JOURNAL   Pharmacogenomics 10 (2), 171-179 (2009)
   PUBMED   19207018
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   2  (residues 1 to 672)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010615.9.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.369913.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     Protein         1..672
                     /product="zinc finger protein 429 isoform b"
                     /calculated_mol_wt=77677
     Region          6..61
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          145..165
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          173..193
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          201..221
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          227..622
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          229..249
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          257..277
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          285..305
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          313..333
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(318,320,322,324..325,328..329,332,346,348,352..353,
                     356..357,360,374,376,378,380..381,384..385,388)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          341..361
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          369..389
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          400..417
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          425..445
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(430,432,434,436..437,440..441,444,458,460,464..465,
                     468..469,472,486,488,490,492..493,496..497,500)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          453..473
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          481..501
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          509..529
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          537..557
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(542,544,546,548..549,552..553,556,570,572,576..577,
                     580..581,584,598,600,602,604..605,608..609,612)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          565..585
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          593..613
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          621..641
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..672
                     /gene="ZNF429"
                     /coded_by="NM_001346912.2:464..2482"
                     /note="isoform b is encoded by transcript variant 2"
                     /db_xref="GeneID:353088"
                     /db_xref="HGNC:HGNC:20817"
                     /db_xref="MIM:621242"
ORIGIN      
        1 mggasdvaie fsleewqcld taqqnlyrnv mlenyrnlvf lgiavskpdl itclekekep
       61 ckmkrhemvd eppvvcshfa edfwpeqdik dsfqkvtlrr ydkrghenlq lrkgyktvgd
      121 cklykggyng lnqcltltqs kmyhcdiyvk vfyafsnadr yktrhtgkkp fqckkcgksf
      181 cmlsqltqhk kihirentyr ckefgnafnq ssaltnhkri yvgekhyrce ecgkafnhys
      241 tltnhkriht gekpykckec gkafsrystl tthkrihsge kpykcdecgk tfsisstftk
      301 hkiihteekp ykckecgkaf nrsstltshk rihtgekpyk ceecgkafnw sstltkhkvi
      361 htgekpykce ecgkafnqss rltrhkkiht geepykfekc grvftcsstl tqdkkihtge
      421 kpynceecgk vftysstltr hkrihteekp ykcnecgkaf nrsshltshr rihtgekpyk
      481 ceecgkafkq ssnlnshkki hsgekpykce ecgkafilss rltqhkkiht gekpykceec
      541 gkafnrssrl tqhkkihtge kpykckqcdk afthssnlss hkkihsgekp ykceecgkaf
      601 nrssrltqhk kihtrekpyk ceecakaftr ssrltqhkki hrmgvvahac npstlggrgg
      661 ritrsgdrdr pg
//
LOCUS       NP_001337523             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337523
VERSION     NP_001337523.1
DBSOURCE    REFSEQ: accession NM_001350594.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (16), as well as variants 8-15 and
            17-19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074968.3488212.1,
                                           SRR1660803.194531.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2144333
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350594.2:1070..1762"
                     /note="isoform e is encoded by transcript variant 16"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001337514             265 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform d [Homo
            sapiens].
ACCESSION   NP_001337514 XP_016866658
VERSION     NP_001337514.1
DBSOURCE    REFSEQ: accession NM_001350585.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 265)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 265)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 265)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 265)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 265)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 265)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 265)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 265)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 265)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 265)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            On Apr 20, 2017 this sequence version replaced XP_016866658.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038192.3057240.1,
                                           SRR1660805.206360.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..265
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform d"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=30337
     Region          8..188
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..265
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350585.2:675..1472"
                     /note="isoform d is encoded by transcript variant 7"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mdaglsfima nhgkvkendi vfdpfvgtgg lliacahfga yvygtdidyn tvhglgkatr
       61 knqkwrgpde niranlrqyg lekyyldvlv sdaskpswrk gtyfdaiitd ppygirestr
      121 rtgsqkeipk giekwekcpe shvpvslsyh lsdmfldlln faaetlvlgg rlvywlpvyt
      181 peyteemvpw hpclelvsnc eqklsshtsr rlitmekvkk fenrdqyshl lsdhflpyqg
      241 hnsfrekyfs gvtkriakee kstqe
//
LOCUS       NP_001287979             161 aa            linear   VRT 18-JUN-2025
DEFINITION  leptin a precursor [Oreochromis niloticus].
ACCESSION   NP_001287979
VERSION     NP_001287979.1
DBSOURCE    REFSEQ: accession NM_001301050.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 161)
  AUTHORS   Shpilman,M., Hollander-Cohen,L., Ventura,T., Gertler,A. and
            Levavi-Sivan,B.
  TITLE     Production, gene structure and characterization of two orthologs of
            leptin and a leptin receptor in tilapia
  JOURNAL   Gen Comp Endocrinol 207, 74-85 (2014)
   PUBMED   24852346
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KF955988.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KF955988.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767853, SAMN00767855
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..161
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG7"
                     /linkage_group="LG7"
     Protein         1..161
                     /product="leptin a precursor"
                     /note="leptin"
                     /calculated_mol_wt=15939
     sig_peptide     1..20
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2178
     CDS             1..161
                     /gene="lepa"
                     /coded_by="NM_001301050.1:1..486"
                     /db_xref="GeneID:100704227"
ORIGIN      
        1 mdyglvllfs lfqalsmgta aplpvevvtm kskvkwmaeq lvvrldkdvq vpvnwtlnpp
       61 addldgtssi etvlngynsl ipdtfkgvsq ikydissltg yihlwrqghc seqrpkpevp
      121 gplqelqshk efiqtvgiea lmrvkeflnl llknldqlet c
//
LOCUS       NP_001336414             247 aa            linear   PRI 18-JUN-2025
DEFINITION  E3 SUMO-protein ligase NSE2 isoform 1 [Homo sapiens].
ACCESSION   NP_001336414
VERSION     NP_001336414.1
DBSOURCE    REFSEQ: accession NM_001349485.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 247)
  AUTHORS   Di Benedetto,C., Oh,J., Choudhery,Z., Shi,W., Valdes,G. and
            Betancur,P.
  TITLE     NSMCE2, a novel super-enhancer-regulated gene, is linked to poor
            prognosis and therapy resistance in breast cancer
  JOURNAL   BMC Cancer 22 (1), 1056 (2022)
   PUBMED   36224576
  REMARK    GeneRIF: NSMCE2, a novel super-enhancer-regulated gene, is linked
            to poor prognosis and therapy resistance in breast cancer.
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 247)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (residues 1 to 247)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (residues 1 to 247)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   5  (residues 1 to 247)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 247)
  AUTHORS   Potts,P.R.
  TITLE     The Yin and Yang of the MMS21-SMC5/6 SUMO ligase complex in
            homologous recombination
  JOURNAL   DNA Repair (Amst) 8 (4), 499-506 (2009)
   PUBMED   19217832
  REMARK    Review article
REFERENCE   7  (residues 1 to 247)
  AUTHORS   Taylor,E.M., Copsey,A.C., Hudson,J.J., Vidot,S. and Lehmann,A.R.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   8  (residues 1 to 247)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   9  (residues 1 to 247)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   10 (residues 1 to 247)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     Human MMS21/NSE2 is a SUMO ligase required for DNA repair
  JOURNAL   Mol Cell Biol 25 (16), 7021-7032 (2005)
   PUBMED   16055714
  REMARK    GeneRIF: the human SMC5/6 complex and the SUMO ligase activity of
            hMMS21 are required for the prevention of DNA damage-induced
            apoptosis by facilitating DNA repair in human cells
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC126366.2 and AC084083.10.
            
            Summary: This gene encodes a member of a family of E3 small
            ubiquitin-related modifier (SUMO) ligases that mediates the
            attachment of a SUMO protein to proteins involved in nuclear
            transport, transcription, chromosome segregation and DNA repair.
            The encoded protein is part of the structural maintenance of
            chromosomes (SMC) 5/6 complex which plays a key role genome
            maintenance, facilitating chromosome segregation and suppressing
            mitotic recombination. A knockout of the orthologous mouse gene is
            lethal prior to embryonic day 10.5. Naturally occurring mutations
            in this gene, that abolish the SUMO ligase activity, are associated
            with primordial dwarfism and extreme insulin resistance. [provided
            by RefSeq, Mar 2017].
            
            Transcript Variant: This variant (2) lacks an alternate exon in the
            5' UTR compared to variant 1. Variants 1-3 encode the same isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189664.19683.1,
                                           SRR18074968.3013688.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.13"
     Protein         1..247
                     /product="E3 SUMO-protein ligase NSE2 isoform 1"
                     /note="E3 SUMO-protein ligase NSE2; methyl
                     methanesulfonate sensitivity gene 21; NSE2 (MMS21)
                     homolog, SMC5-SMC6 complex SUMO ligase; non-structural
                     maintenance of chromosomes element 2 homolog; zinc finger,
                     MIZ-type containing 7; non-SMC element 2, MMS21 homolog;
                     NSMCE2/PVT1 fusion; PVT1/NSMCE2 fusion; E3 SUMO-protein
                     transferase NSE2"
                     /calculated_mol_wt=27801
     Site            1
                     /site_type="acetylation"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0007744|PubMed:20068231; propagated from
                     UniProtKB/Swiss-Prot (Q96MF7.2)"
     Site            116
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q96MF7.2)"
     Region          167..237
                     /region_name="SPL-RING_NSE2"
                     /note="SPL-RING finger found in E3 SUMO-protein ligase
                     NSE2 and similar proteins; cd16651"
                     /db_xref="CDD:438313"
     CDS             1..247
                     /gene="NSMCE2"
                     /gene_synonym="C8orf36; MMS21; NSE2; ZMIZ7"
                     /coded_by="NM_001349485.2:114..857"
                     /note="isoform 1 is encoded by transcript variant 2"
                     /db_xref="CCDS:CCDS6356.1"
                     /db_xref="GeneID:286053"
                     /db_xref="HGNC:HGNC:26513"
                     /db_xref="MIM:617246"
ORIGIN      
        1 mpgrsssnsg stgfisfsgv esalsslknf qacinsgmdt assvaldlve sqtevsseys
       61 mdkamvefat ldrqlnhyvk avqstinhvk eerpekipdl kllvekkfla lqsknsdadf
      121 qnnekfvqfk qqlkelkkqc glqadreadg tegvdediiv tqsqtnftcp itkeemkkpv
      181 knkvcghtye edaivrmies rqkrkkkayc pqigcshtdi rksdliqdea lrraienhnk
      241 krhrhse
//
LOCUS       NP_001266418             521 aa            linear   VRT 18-JUN-2025
DEFINITION  cytochrome P450 1A1 [Oreochromis niloticus].
ACCESSION   NP_001266418 XP_003437604
VERSION     NP_001266418.1
DBSOURCE    REFSEQ: accession NM_001279489.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from FJ389918.2.
            
            On Jul 22, 2013 this sequence version replaced XP_003437604.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FJ389918.2 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG1"
                     /linkage_group="LG1"
     Protein         1..521
                     /product="cytochrome P450 1A1"
                     /EC_number="1.14.14.1"
                     /note="cytochrome P450 1A"
                     /calculated_mol_wt=59122
     Region          75..511
                     /region_name="CYP1A"
                     /note="cytochrome P450 family 1, subfamily A; cd20676"
                     /db_xref="CDD:410769"
     Site            order(111,127,136,140,319,322..323,326..327,386..387,
                     390..391,393,416,455..456,461,463..465,469)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:410769"
     Site            order(120..121,125,127..128,226..230,256,259..260,263,
                     317..318,321..322,324..326,387,390..391,502..503,505)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:410769"
     CDS             1..521
                     /gene="cyp1a"
                     /coded_by="NM_001279489.1:135..1700"
                     /db_xref="GeneID:100706338"
ORIGIN      
        1 malmilpfig alsvshvlva vttaclvyli iknaqnkipe glqqlpgpkp lpiignllel
       61 gkrpylslts mskrygdvfq iqigmrpvvv lsgnetvrqa likqgdefag rpdlysfryi
      121 ndgkslsfst dqagiwrarr klaysalrsf snlegttpey scaleehisk eaeylikeln
      181 tvmktkgsfd pfryvvvsva nvicgtcfgr rydhhddelv slvnlsddfv kvvgsgnpad
      241 fipllqylps tkmkkfvsln arfskfvqkl vtehyatfdk dnirditdsl idhcedrkld
      301 enaniqmsde kivgivndlf gagfdtista lswslmyfva ypeiqnrlfe emkekvgldr
      361 mpvfsdrnnl plleayilel frhssylpft iphcttkdts lngyfipkdt cvfinqwqin
      421 hdpelwedpf sfkpgrflna dgtevnkveg ekvmtfglgk rrcigeviar nelflflail
      481 iqklnfqalp gdqldltpey gltmkhkryh lratmrvkne q
//
LOCUS       NP_057344                526 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein Helios isoform 1 [Homo sapiens].
ACCESSION   NP_057344
VERSION     NP_057344.2
DBSOURCE    REFSEQ: accession NM_016260.3
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 526)
  AUTHORS   Velde,H.M., Vaseghi-Shanjani,M., Smits,J.J., Ramakrishnan,G.,
            Oostrik,J., Wesdorp,M., Astuti,G., Yntema,H.G., Hoefsloot,L.,
            Lanting,C.P., Huynen,M.A., Lehman,A., Turvey,S.E., Pennings,R.J.E.
            and Kremer,H.
  CONSRTM   DOOFNL Consortium
  TITLE     Exome variant prioritization in a large cohort of hearing-impaired
            individuals indicates IKZF2 to be associated with non-syndromic
            hearing loss and guides future research of unsolved cases
  JOURNAL   Hum Genet 143 (11), 1379-1399 (2024)
   PUBMED   39406892
REFERENCE   2  (residues 1 to 526)
  AUTHORS   Lukasik,M., Telec,M., Kazmierski,R., Wojtasz,I.,
            Andrzejewska-Gorczynska,N., Kociemba,W., Dworacki,G., Kozubski,W.P.
            and Frydrychowicz,M.
  TITLE     Temporal changes in regulatory T cell subsets defined by the
            transcription factor Helios in stroke and their potential role in
            stroke-associated infection: a prospective case-control study
  JOURNAL   J Neuroinflammation 20 (1), 275 (2023)
   PUBMED   37996909
  REMARK    GeneRIF: Temporal changes in regulatory T cell subsets defined by
            the transcription factor Helios in stroke and their potential role
            in stroke-associated infection: a prospective case-control study.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 526)
  AUTHORS   Mohajeri,A., Vaseghi-Shanjani,M., Rosenfeld,J.A., Yang,G.X., Lu,H.,
            Sharma,M., Lin,S., Salman,A., Waqas,M., Sababi Azamian,M.,
            Worley,K.C., Del Bel,K.L., Kozak,F.K., Rahmanian,R., Biggs,C.M.,
            Hildebrand,K.J., Lalani,S.R., Nicholas,S.K., Scott,D.A.,
            Mostafavi,S., van Karnebeek,C., Henkelman,E., Halparin,J.,
            Yang,C.L., Armstrong,L., Turvey,S.E. and Lehman,A.
  CONSRTM   Undiagnosed Diseases Network; Care4Rare Canada Consortium
  TITLE     Dominant negative variants in IKZF2 cause ICHAD syndrome, a new
            disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay
  JOURNAL   J Med Genet 60 (11), 1092-1104 (2023)
   PUBMED   37316189
  REMARK    GeneRIF: Dominant negative variants in IKZF2 cause ICHAD syndrome,
            a new disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay.
REFERENCE   4  (residues 1 to 526)
  AUTHORS   Tarighi,M., Shahbazi,M., Saadat,P., Daraei,A., Alizadeh Khatir,A.,
            Rahimifard,K. and Mohammadnia-Afrouzi,M.
  TITLE     Decreased frequency of regulatory T cells and level of helios gene
            expression in secondary progressive multiple sclerosis patients:
            Evidence about the development of multiple sclerosis
  JOURNAL   Int Immunopharmacol 116, 109797 (2023)
   PUBMED   36738680
  REMARK    GeneRIF: Decreased frequency of regulatory T cells and level of
            helios gene expression in secondary progressive multiple sclerosis
            patients: Evidence about the development of multiple sclerosis.
REFERENCE   5  (residues 1 to 526)
  AUTHORS   Zhang,H., Jadhav,R.R., Cao,W., Goronzy,I.N., Zhao,T.V., Jin,J.,
            Ohtsuki,S., Hu,Z., Morales,J., Greenleaf,W.J., Weyand,C.M. and
            Goronzy,J.J.
  TITLE     Aging-associated HELIOS deficiency in naive CD4+ T cells alters
            chromatin remodeling and promotes effector cell responses
  JOURNAL   Nat Immunol 24 (1), 96-109 (2023)
   PUBMED   36510022
  REMARK    GeneRIF: Aging-associated HELIOS deficiency in naive CD4[+] T cells
            alters chromatin remodeling and promotes effector cell responses.
REFERENCE   6  (residues 1 to 526)
  AUTHORS   Nakase,K., Ishimaru,F., Fujii,K., Tabayashi,T., Kozuka,T.,
            Sezaki,N., Matsuo,Y. and Harada,M.
  TITLE     Overexpression of novel short isoforms of Helios in a patient with
            T-cell acute lymphoblastic leukemia
  JOURNAL   Exp Hematol 30 (4), 313-317 (2002)
   PUBMED   11937265
  REMARK    GeneRIF: Novel short isoforms of Helios are overexpressed in a
            patient with T-cell acute lymphoblastic leukemia and may contribute
            to the development of T-cell malignancies. Data for unaltered
            Helios indicates tumor suppressor function.
REFERENCE   7  (residues 1 to 526)
  AUTHORS   Perdomo,J., Holmes,M., Chong,B. and Crossley,M.
  TITLE     Eos and pegasus, two members of the Ikaros family of proteins with
            distinct DNA binding activities
  JOURNAL   J Biol Chem 275 (49), 38347-38354 (2000)
   PUBMED   10978333
REFERENCE   8  (residues 1 to 526)
  AUTHORS   Hosokawa,Y., Maeda,Y. and Seto,M.
  TITLE     Human Helios, an Ikaros-related zinc finger DNA binding protein:
            cDNA cloning and tissue expression pattern
  JOURNAL   Immunogenetics 50 (1-2), 106-108 (1999)
   PUBMED   10541817
REFERENCE   9  (residues 1 to 526)
  AUTHORS   Kelley,C.M., Ikeda,T., Koipally,J., Avitahl,N., Wu,L.,
            Georgopoulos,K. and Morgan,B.A.
  TITLE     Helios, a novel dimerization partner of Ikaros expressed in the
            earliest hematopoietic progenitors
  JOURNAL   Curr Biol 8 (9), 508-515 (1998)
   PUBMED   9560339
REFERENCE   10 (residues 1 to 526)
  AUTHORS   Hahm,K., Cobb,B.S., McCarty,A.S., Brown,K.E., Klug,C.A., Lee,R.,
            Akashi,K., Weissman,I.L., Fisher,A.G. and Smale,S.T.
  TITLE     Helios, a T cell-restricted Ikaros family member that
            quantitatively associates with Ikaros at centromeric
            heterochromatin
  JOURNAL   Genes Dev 12 (6), 782-796 (1998)
   PUBMED   9512513
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC079610.4, AF130863.1,
            AC013736.9, AC108066.3 and AI458439.1.
            
            On Dec 8, 2006 this sequence version replaced NP_057344.1.
            
            Summary: This gene encodes a member of the Ikaros family of
            zinc-finger proteins. Three members of this protein family (Ikaros,
            Aiolos and Helios) are hematopoietic-specific transcription factors
            involved in the regulation of lymphocyte development. This protein
            forms homo- or hetero-dimers with other Ikaros family members, and
            is thought to function predominantly in early hematopoietic
            development. Multiple transcript variants encoding different
            isoforms have been found for this gene, but the biological validity
            of some variants has not been determined. [provided by RefSeq, Jul
            2008].
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.644759.1,
                                           SRR14038195.2393615.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: lack of evidence for use of
                                                upstream AUG
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..526
                     /product="zinc finger protein Helios isoform 1"
                     /note="zinc finger protein, subfamily 1A, 2 (Helios); zinc
                     finger DNA binding protein Helios; zinc finger protein
                     Helios; ikaros family zinc finger protein 2"
                     /calculated_mol_wt=59443
     Region          28..91
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            56
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            78
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            79
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Region          114..134
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(119,121,123,125..126,129..130,133,147,149,153..154,
                     157..158,161,175,177,179,181..182,185..186,189)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          127..151
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          142..162
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          154..179
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          170..190
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          186..207
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          198..219
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            288
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:19608861; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Region          370..435
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKS7.2)"
     CDS             1..526
                     /gene="IKZF2"
                     /gene_synonym="ANF1A2; HELIOS; ICHAD; IMDIA; ZNF1A2;
                     ZNFN1A2"
                     /coded_by="NM_016260.3:273..1853"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS2395.1"
                     /db_xref="GeneID:22807"
                     /db_xref="HGNC:HGNC:13177"
                     /db_xref="MIM:606234"
ORIGIN      
        1 meteaidgyi tcdnelsper ehsnmaidlt sstpngqhas pshmtstnsv klemqsdeec
       61 drkplsrede irghdegssl eepliessev adnrkvqelq geggirlpng klkcdvcgmv
      121 cigpnvlmvh krshtgerpf hcnqcgasft qkgnllrhik lhsgekpfkc pfcsyacrrr
      181 daltghlrth svgkphkcny cgrsykqrss leehkerchn ylqnvsmeaa gqvmshhvpp
      241 medckeqepi mdnnislvpf erpavieklt gnmgkrksst pqkfvgeklm rfsypdihfd
      301 mnltyekeae lmqshmmdqa innaitylga ealhplmqhp pstiaevapv issaysqvyh
      361 pnrierpisr etadshennm dgpislirpk srpqereasp snscldstds esshddhqsy
      421 qghpalnpkr kqspaymked vkaldttkap kgslkdiykv fngegeqira fkcehcrvlf
      481 ldhvmytihm gchgyrdple cnicgyrsqd ryefsshivr gehtfh
//
LOCUS       NP_001398002             316 aa            linear   PRI 18-JUN-2025
DEFINITION  non-structural maintenance of chromosomes element 4 homolog A
            isoform 3 [Homo sapiens].
ACCESSION   NP_001398002 XP_047281356
VERSION     NP_001398002.1
DBSOURCE    REFSEQ: accession NM_001411073.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 316)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (residues 1 to 316)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (residues 1 to 316)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   4  (residues 1 to 316)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   5  (residues 1 to 316)
  AUTHORS   van der Crabben,S.N., Hennus,M.P., McGregor,G.A., Ritter,D.I.,
            Nagamani,S.C., Wells,O.S., Harakalova,M., Chinn,I.K., Alt,A.,
            Vondrova,L., Hochstenbach,R., van Montfrans,J.M.,
            Terheggen-Lagro,S.W., van Lieshout,S., van Roosmalen,M.J.,
            Renkens,I., Duran,K., Nijman,I.J., Kloosterman,W.P., Hennekam,E.,
            Orange,J.S., van Hasselt,P.M., Wheeler,D.A., Palecek,J.J.,
            Lehmann,A.R., Oliver,A.W., Pearl,L.H., Plon,S.E., Murray,J.M. and
            van Haaften,G.
  TITLE     Destabilized SMC5/6 complex leads to chromosome breakage syndrome
            with severe lung disease
  JOURNAL   J Clin Invest 126 (8), 2881-2892 (2016)
   PUBMED   27427983
REFERENCE   6  (residues 1 to 316)
  AUTHORS   Doyle,J.M., Gao,J., Wang,J., Yang,M. and Potts,P.R.
  TITLE     MAGE-RING protein complexes comprise a family of E3 ubiquitin
            ligases
  JOURNAL   Mol Cell 39 (6), 963-974 (2010)
   PUBMED   20864041
REFERENCE   7  (residues 1 to 316)
  AUTHORS   Taylor,E.M., Copsey,A.C., Hudson,J.J., Vidot,S. and Lehmann,A.R.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   8  (residues 1 to 316)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   9  (residues 1 to 316)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   10 (residues 1 to 316)
  AUTHORS   Hu,B., Liao,C., Millson,S.H., Mollapour,M., Prodromou,C.,
            Pearl,L.H., Piper,P.W. and Panaretou,B.
  TITLE     Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex
  JOURNAL   Mol Microbiol 55 (6), 1735-1750 (2005)
   PUBMED   15752197
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL731566.7.
            
            On Aug 20, 2022 this sequence version replaced XP_047281356.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC005212.1, SRR14038192.251170.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.13"
     Protein         1..316
                     /product="non-structural maintenance of chromosomes
                     element 4 homolog A isoform 3"
                     /note="non-structural maintenance of chromosomes element 4
                     homolog A; non-SMC element 4 homolog A; NSE4 homolog A,
                     SMC5-SMC6 complex component; NSE4 homolog, SMC5-SMC6
                     complex component A"
                     /calculated_mol_wt=35728
     Region          1..69
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NXX6.2)"
     Region          133..187
                     /region_name="Nse4-Nse3_bdg"
                     /note="Binding domain of Nse4/EID3 to Nse3-MAGE;
                     pfam15412"
                     /db_xref="CDD:464708"
     CDS             1..316
                     /gene="NSMCE4A"
                     /gene_synonym="C10orf86; NS4EA; NSE4A"
                     /coded_by="NM_001411073.1:53..1003"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS91366.1"
                     /db_xref="GeneID:54780"
                     /db_xref="HGNC:HGNC:25935"
                     /db_xref="MIM:612987"
ORIGIN      
        1 msgdssgrgp egrgrgrdph rdrtrsrsrs rsplsprsrr gsarerreap erpsledtep
       61 sdsgdemmdp asleaeadqg lcrqirhqyr alinsvqqnr edilnagdkl tevleeantl
      121 fnevsrarea vldahflvla sdlgkekakq lrsdlssfdm lryvetllth mgvnpleaee
      181 lirdedspdf efivydswki tgrtaentfn kthtfhfllg siygecpvpk prvdrprkvp
      241 viqeerampa qlrrmeeshq eatekeveri lgllqtyfre drdsltlspr lecsgtisth
      301 cnlhlldssn spasas
//
LOCUS       NP_001266652             258 aa            linear   VRT 18-JUN-2025
DEFINITION  nuclear receptor subfamily 0 group B member 2a [Oreochromis
            niloticus].
ACCESSION   NP_001266652 XP_003452125
VERSION     NP_001266652.1
DBSOURCE    REFSEQ: accession NM_001279723.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 258)
  AUTHORS   Wang,D.S., Kobayashi,T., Senthilkumaran,B., Sakai,F.,
            Sudhakumari,C.C., Suzuki,T., Yoshikuni,M., Matsuda,M., Morohashi,K.
            and Nagahama,Y.
  TITLE     Molecular cloning of DAX1 and SHP cDNAs and their expression
            patterns in the Nile tilapia, Oreochromis niloticus
  JOURNAL   Biochem Biophys Res Commun 297 (3), 632-640 (2002)
   PUBMED   12270141
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY135398.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003452125.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY135398.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..258
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG11"
                     /linkage_group="LG11"
     Protein         1..258
                     /product="nuclear receptor subfamily 0 group B member 2a"
                     /note="orphan nuclear receptor SHP; nuclear receptor
                     subfamily 0 group B member 2"
                     /calculated_mol_wt=28788
     Region          38..255
                     /region_name="NR_LBD"
                     /note="The ligand binding domain of nuclear receptors, a
                     family of ligand-activated transcription regulators;
                     cl11397"
                     /db_xref="CDD:472173"
     Site            order(61..62,65,68..69,98..99,102..103,106,109,150)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:132726"
     Site            order(70,73,77,82,87..88,90..91,94..95)
                     /site_type="active"
                     /note="coregulator recognition site [active]"
                     /db_xref="CDD:132726"
     CDS             1..258
                     /gene="nr0b2a"
                     /gene_synonym="nr0b2"
                     /coded_by="NM_001279723.1:85..861"
                     /db_xref="GeneID:100533979"
ORIGIN      
        1 mdsacrcsts sdrtsnpily nilsqmdgsr lsqgnfsyns vphrckcear rtvclkrpse
       61 ickeasavlv ktlnfmknlp afnqlppndq fallkscwap lfilglaqer vdfevtdipt
      121 dsmlkkilln rpespevere qptmagvskl vsclkkfwsl dlspkeyayl kgttifnpdv
      181 pdlkaalfve glqqeaqqal skvvqllhpg dgdrfarill tasmlqsitp slitelffrp
      241 vigqanllel lvdmlfcr
//
LOCUS       NP_001266384             574 aa            linear   VRT 18-JUN-2025
DEFINITION  growth hormone receptor b precursor [Oreochromis niloticus].
ACCESSION   NP_001266384 XP_003440121
VERSION     NP_001266384.1
DBSOURCE    REFSEQ: accession NM_001279455.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 574)
  AUTHORS   Ma,X., Liu,X., Zhang,Y., Zhu,P., Ye,W. and Lin,H.
  TITLE     Two growth hormone receptors in Nile tilapia (Oreochromis
            niloticus): molecular characterization, tissue distribution and
            expression profiles in the gonad during the reproductive cycle
  JOURNAL   Comp Biochem Physiol B Biochem Mol Biol 147 (2), 325-339 (2007)
   PUBMED   17341448
REFERENCE   2  (residues 1 to 574)
  AUTHORS   Jiao,B., Huang,X., Chan,C.B., Zhang,L., Wang,D. and Cheng,C.H.
  TITLE     The co-existence of two growth hormone receptors in teleost fish
            and their differential signal transduction, tissue distribution and
            hormonal regulation of expression in seabream
  JOURNAL   J Mol Endocrinol 36 (1), 23-40 (2006)
   PUBMED   16461924
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EF052862.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003440121.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY973233.1, EF052862.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG7"
                     /linkage_group="LG7"
     Protein         1..574
                     /product="growth hormone receptor b precursor"
                     /note="growth hormone receptor type 2; growth hormone
                     receptor II; growth hormone rceptor type 2"
                     /calculated_mol_wt=61622
     sig_peptide     1..24
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2570
     Region          134..234
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Site            order(134,207,222)
                     /site_type="active"
                     /note="Interdomain contacts [active]"
                     /db_xref="CDD:238020"
     Site            order(223,226,228..229)
                     /site_type="active"
                     /note="Cytokine receptor motif [active]"
                     /db_xref="CDD:238020"
     Region          295..549
                     /region_name="GHBP"
                     /note="Growth hormone receptor binding; pfam12772"
                     /db_xref="CDD:463696"
     CDS             1..574
                     /gene="ghrb"
                     /gene_synonym="ghr; ghr2"
                     /coded_by="NM_001279455.1:40..1764"
                     /db_xref="GeneID:100534534"
ORIGIN      
        1 maptvtmllf vlhiltalvl qsasepvlse rrphltscas pdmmtfrcrw nvgpfqnlsd
       61 pralrlfyfr hvppplsskn wtecphyste tpnecffdqn htsiwtyynv qlrsrdetil
      121 ydekgffvnd ivqpdppvsl nwtllnvslt gihydillsw kpppssdvet gwmklqyevq
      181 hrdnsssvwe mvdpvsstqc slyglqtnin heirvrckml ggkefgefse svfihipskv
      241 srfpvvalli fgalclvgil mlviisqqek wmvillppvp gpkikgidse llksgklrel
      301 tsilggppdl rpelynsdpw vefidldiee qsdrvtdldt dclmnhhlss ncsplslgfr
      361 dddsgrascc dpdlpcdpep spflplvpnl alsqetlcaa tsepsspiqs cnsgelpsfv
      421 tgrdtlytqv tevrssgkvl llpeeqtere kmsskekede ivvekekkef qllvmnadhr
      481 dytselnagk tspelstgdl tepcktfpsp hhesntttpp pipapvytvv egvdrqnsll
      541 lspnsapaph liipknmptp dgyltadllg sitp
//
LOCUS       NP_001268780             200 aa            linear   VRT 18-JUN-2025
DEFINITION  Golgi apparatus membrane protein TVP23 homolog B [Oreochromis
            niloticus].
ACCESSION   NP_001268780 XP_003448680
VERSION     NP_001268780.1
DBSOURCE    REFSEQ: accession NM_001281851.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 200)
  AUTHORS   Lee,B.Y., Howe,A.E., Conte,M.A., D'Cotta,H., Pepey,E.,
            Baroiller,J.F., di Palma,F., Carleton,K.L. and Kocher,T.D.
  TITLE     An EST resource for tilapia based on 17 normalized libraries and
            assembly of 116,899 sequence tags
  JOURNAL   BMC Genomics 11, 278 (2010)
   PUBMED   20433739
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from GR698337.1,
            GR674546.1, GR646151.1 and GR589204.1.
            
            On Aug 9, 2013 this sequence version replaced XP_003448680.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GR698337.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..200
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG8"
                     /linkage_group="LG8"
     Protein         1..200
                     /product="Golgi apparatus membrane protein TVP23 homolog
                     B"
                     /note="protein FAM18B1-like"
                     /calculated_mol_wt=22549
     Region          29..169
                     /region_name="DUF846"
                     /note="Eukaryotic protein of unknown function (DUF846);
                     pfam05832"
                     /db_xref="CDD:461754"
     CDS             1..200
                     /gene="tvp23b"
                     /coded_by="NM_001281851.1:58..660"
                     /db_xref="GeneID:100698590"
ORIGIN      
        1 mladtndedv slfdaeddag krskksgvkh pvaaffhlff rvsaiivyll aeliggsfia
       61 cmvtiillls cdfwtvknit grlmvglrww nqvdddgrsh wvfesrkgtg kqqasdsesr
      121 ifwlglivcp ilwvifvfst lfsfrikwmp vvimgvvlqg anlygyvrck vggktslknm
      181 atnyfgrqfl kqtlskeees
//
LOCUS       NP_659547                266 aa            linear   PRI 18-JUN-2025
DEFINITION  non-structural maintenance of chromosomes element 1 homolog [Homo
            sapiens].
ACCESSION   NP_659547
VERSION     NP_659547.2
DBSOURCE    REFSEQ: accession NM_145080.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 266)
  AUTHORS   Lorite,N.P., Apostolova,S., Guasch-Valles,M., Pryer,A., Unzueta,F.,
            Freire,R., Sole-Soler,R., Pedraza,N., Dolcet,X., Gari,E., Agell,N.,
            Taylor,E.M., Colomina,N. and Torres-Rosell,J.
  TITLE     Crucial role of the NSE1 RING domain in Smc5/6 stability and
            FANCM-independent fork progression
  JOURNAL   Cell Mol Life Sci 81 (1), 251 (2024)
   PUBMED   38847937
  REMARK    GeneRIF: Crucial role of the NSE1 RING domain in Smc5/6 stability
            and FANCM-independent fork progression.
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 266)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (residues 1 to 266)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
  REMARK    GeneRIF: Molecular Insights into the Architecture of the Human
            SMC5/6 Complex.
REFERENCE   4  (residues 1 to 266)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   5  (residues 1 to 266)
  AUTHORS   van der Crabben,S.N., Hennus,M.P., McGregor,G.A., Ritter,D.I.,
            Nagamani,S.C., Wells,O.S., Harakalova,M., Chinn,I.K., Alt,A.,
            Vondrova,L., Hochstenbach,R., van Montfrans,J.M.,
            Terheggen-Lagro,S.W., van Lieshout,S., van Roosmalen,M.J.,
            Renkens,I., Duran,K., Nijman,I.J., Kloosterman,W.P., Hennekam,E.,
            Orange,J.S., van Hasselt,P.M., Wheeler,D.A., Palecek,J.J.,
            Lehmann,A.R., Oliver,A.W., Pearl,L.H., Plon,S.E., Murray,J.M. and
            van Haaften,G.
  TITLE     Destabilized SMC5/6 complex leads to chromosome breakage syndrome
            with severe lung disease
  JOURNAL   J Clin Invest 126 (8), 2881-2892 (2016)
   PUBMED   27427983
REFERENCE   6  (residues 1 to 266)
  AUTHORS   Taylor,E.M., Copsey,A.C., Hudson,J.J., Vidot,S. and Lehmann,A.R.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   7  (residues 1 to 266)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   8  (residues 1 to 266)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   9  (residues 1 to 266)
  AUTHORS   Harvey,S.H., Sheedy,D.M., Cuddihy,A.R. and O'Connell,M.J.
  TITLE     Coordination of DNA damage responses via the Smc5/Smc6 complex
  JOURNAL   Mol Cell Biol 24 (2), 662-674 (2004)
   PUBMED   14701739
REFERENCE   10 (residues 1 to 266)
  AUTHORS   Fujioka,Y., Kimata,Y., Nomaguchi,K., Watanabe,K. and Kohno,K.
  TITLE     Identification of a novel non-structural maintenance of chromosomes
            (SMC) component of the SMC5-SMC6 complex involved in DNA repair
  JOURNAL   J Biol Chem 277 (24), 21585-21591 (2002)
   PUBMED   11927594
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB463393.1 and BU685363.1.
            
            On May 5, 2006 this sequence version replaced NP_659547.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ277346.1, SRR14038194.2896771.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000361439.9/ ENSP00000355077.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p12.1"
     Protein         1..266
                     /product="non-structural maintenance of chromosomes
                     element 1 homolog"
                     /EC_number="2.3.2.27"
                     /note="non-SMC element 1 homolog; NSE1 homolog, SMC5-SMC6
                     complex component"
                     /calculated_mol_wt=30724
     Region          1..102
                     /region_name="Interaction with NSMCE3.
                     /evidence=ECO:0000269|PubMed:20864041"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8WV22.5)"
     Region          16..175
                     /region_name="SMC_Nse1"
                     /note="Nse1 non-SMC component of SMC5-6 complex;
                     pfam07574"
                     /db_xref="CDD:462214"
     Region          189..235
                     /region_name="RING-CH-C4HC3_NSE1"
                     /note="RING-CH finger, H2 subclass (C4HC3-type), found in
                     non-structural maintenance of chromosomes (SMC) element 1
                     homolog (NSE1) and similar proteins; cd16493"
                     /db_xref="CDD:438156"
     Region          246..266
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8WV22.5)"
     Site            251
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q8WV22.5)"
     CDS             1..266
                     /gene="NSMCE1"
                     /gene_synonym="NSE1"
                     /coded_by="NM_145080.4:79..879"
                     /db_xref="CCDS:CCDS10628.2"
                     /db_xref="GeneID:197370"
                     /db_xref="HGNC:HGNC:29897"
                     /db_xref="MIM:617263"
ORIGIN      
        1 mqgstrrmgv mtdvhrrflq llmthgvlee wdvkrlqthc ykvhdrnatv dkledfinni
       61 nsvleslyie ikrgvteddg rpiyalvnla ttsiskmatd faeneldlfr kaleliidse
      121 tgfasstnil nlvdqlkgkk mrkkeaeqvl qkfvqnkwli ekegeftlhg railemeqyi
      181 retypdavki cnichslliq gqscetcgir mhlpcvakyf qsnaeprcph cndywpheip
      241 kvfdpekere sgvlksnkks lrsrqh
//
LOCUS       NP_001266517             701 aa            linear   VRT 18-JUN-2025
DEFINITION  follicle-stimulating hormone receptor precursor [Oreochromis
            niloticus].
ACCESSION   NP_001266517 XP_003441812
VERSION     NP_001266517.1
DBSOURCE    REFSEQ: accession NM_001279588.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB041762.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003441812.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB041762.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767858, SAMN00767860
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG8"
                     /linkage_group="LG8"
     Protein         1..701
                     /product="follicle-stimulating hormone receptor precursor"
                     /note="gonadotropin receptor I"
                     /calculated_mol_wt=76247
     sig_peptide     1..20
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2226
     Region          <57..314
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          86..110
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          111..135
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          136..160
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          161..182
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          187..211
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          212..234
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          235..259
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          260..283
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          375..647
                     /region_name="7tmA_Glyco_hormone_R"
                     /note="glycoprotein hormone receptors, member of the class
                     A family of seven-transmembrane G protein-coupled
                     receptors; cd15136"
                     /db_xref="CDD:320264"
     Region          375..400
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320264"
     Region          407..432
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320264"
     Site            order(428,431..432,452..457,459..460,463,508,510..514,536,
                     539..541,543..545,547..548,595,598..599,601..602,605,
                     614..615,617..619,622,625..626)
                     /site_type="other"
                     /note="putative peptide ligand binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:320264"
     Region          452..482
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320264"
     Region          494..516
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320264"
     Region          536..565
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320264"
     Region          575..605
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320264"
     Region          615..640
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320264"
     CDS             1..701
                     /gene="fshr"
                     /gene_synonym="gth-ri"
                     /coded_by="NM_001279588.1:93..2198"
                     /db_xref="GeneID:100534395"
ORIGIN      
        1 mmlvmtlmml livtikmaaa sahgsemdir pgfhpslakq tsclsyqvmf gvtafpsnis
       61 naqclevkqt qireiqqgtl sslqhlmelt isendllesi gafafsglph ltkiliskna
      121 alrnigafvf snlpelseii itkskhlsfi hpdafrnmar lrfltisntg lrifpdfski
      181 hstacflldl qdnshikrvp anafrglctq tfaeirltrn gikevasdaf ngtkmhrlfl
      241 ggnrqlthis pnafvgssel vvldvsetal tslpdsildg lkrliaesaf nlkelppiql
      301 ftklhqaklt ypshccafln mhrnrsrwhs lcdnpeaknn lhffreycsn stnitcspap
      361 ddfnpcedim satplriliw iisvlallgn avvllvllgs rykltvprfl mchlafadlc
      421 mgiylvviat vdmltrgryy nyaidwqmgl gcnaagfftv faselsvftl taitverwht
      481 ithalrldrk lrlrhaciim tigwifslla allptvgiss ygkvsiclpm dveslvsqfy
      541 vvcllllnil affcvcgcyl siyltfrkps saaahadtrv aqrmavlift dficmapisf
      601 faisaalklp litvsdskll lvlfypinsc snpflyafft rnfrrdffll aarfglfktr
      661 aqiyrtesss cqqptwtspk nsrvilyslv ntlsldgkqe c
//
LOCUS       NP_001307671             347 aa            linear   PRI 18-JUN-2025
DEFINITION  queuosine-tRNA galactosyltransferase isoform b [Homo sapiens].
ACCESSION   NP_001307671 XP_011521833 XP_011545060
VERSION     NP_001307671.1
DBSOURCE    REFSEQ: accession NM_001320742.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 347)
  AUTHORS   Zhao,X., Ma,D., Ishiguro,K., Saito,H., Akichika,S., Matsuzawa,I.,
            Mito,M., Irie,T., Ishibashi,K., Wakabayashi,K., Sakaguchi,Y.,
            Yokoyama,T., Mishima,Y., Shirouzu,M., Iwasaki,S., Suzuki,T. and
            Suzuki,T.
  TITLE     Glycosylated queuosines in tRNAs optimize translational rate and
            post-embryonic growth
  JOURNAL   Cell 186 (25), 5517-5535 (2023)
   PUBMED   37992713
REFERENCE   2  (residues 1 to 347)
  AUTHORS   Zheng,H., Li,Y., Ji,C., Li,J., Zhang,J., Yin,G., Xu,J., Ye,X.,
            Wu,M., Zou,X., Gu,S., Xie,Y. and Mao,Y.
  TITLE     Characterization of a cDNA encoding a protein with limited
            similarity to beta1, 3-N-acetylglucosaminyltransferase
  JOURNAL   Mol Biol Rep 31 (3), 171-175 (2004)
   PUBMED   15560372
  REMARK    GeneRIF: beta3-GnTL1 is similar to beta1,
            3-N-acetylglucosaminyltransferase
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130371.4.
            
            On or before Mar 4, 2016 this sequence version replaced
            XP_011521833.1, XP_011545060.1.
            
            Transcript Variant: This variant (2) contains an alternate exon,
            resulting in a novel 5' UTR and the use of an alternate start
            codon, compared to variant 1. The encoded isoform (b) has a
            distinct N-terminus, and is shorter than isoform a.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.117225.1,
                                           SRR18074967.1857533.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.3"
     Protein         1..347
                     /product="queuosine-tRNA galactosyltransferase isoform b"
                     /EC_number="2.4.1.-"
                     /note="UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 8;
                     UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase-like protein 1;
                     BGnT-like protein 1; UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase like 1;
                     beta3Gn-T-like protein 1;
                     beta1,3-N-acetylglucosaminyltransferase-like protein 1;
                     beta-1,3-Gn-T8"
                     /calculated_mol_wt=39496
     Region          8..226
                     /region_name="beta3GnTL1_like"
                     /note="Beta 1, 3-N-acetylglucosaminyltransferase is
                     essential for the formation of poly-N-acetyllactosamine;
                     cd06913"
                     /db_xref="CDD:133063"
     CDS             1..347
                     /gene="QTGAL"
                     /gene_synonym="3-Gn-T8; B3GNT8; B3GNTL1; beta-1;
                     beta3Gn-T8; beta3GnTL1; BGnT-8"
                     /coded_by="NM_001320742.2:135..1178"
                     /note="isoform b is encoded by transcript variant 2"
                     /db_xref="GeneID:146712"
                     /db_xref="HGNC:HGNC:21727"
                     /db_xref="MIM:615337"
ORIGIN      
        1 mhhhtrsiil pvhnaepwld eclrsvlqqd fegtmelsvf ndaskdksga iiekwrvkle
       61 dsgvhviigg hdspsprgvg yaknqavaqs sgsylcflds ddvmmpqrvr lqheaavqhp
      121 ssiigcrvrr dppnsteryt rwinqltpeq lltqvftsng ptvimptwfc srawfshvgp
      181 fneggqgvpe dllffyehlr kgggvirvdq slllyrhhpq aathcvlett iwthrvrfle
      241 eqalprwaaf tiwnagkqgr rlyrsltags qrkvvafcdv denkirkgfy chedsqerpk
      301 pripilhfra arppfvicvk ldltggafed nlrslhlqeg qdflhfs
//
LOCUS       NP_001347778             404 aa            linear   VRT 18-JUN-2025
DEFINITION  growth/differentiation factor 10b precursor [Oreochromis
            niloticus].
ACCESSION   NP_001347778 XP_005474367
VERSION     NP_001347778.1
DBSOURCE    REFSEQ: accession NM_001360849.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            MKQE02000013.1.
            
            On Feb 15, 2018 this sequence version replaced XP_005474367.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GBCP01030572.1, GBAY01015060.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG13"
                     /linkage_group="LG13"
     Protein         1..404
                     /product="growth/differentiation factor 10b precursor"
                     /calculated_mol_wt=42867
     sig_peptide     1..19
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2156
     Region          15..100
                     /region_name="Tissue_fac"
                     /note="Tissue factor; pfam01108"
                     /db_xref="CDD:460067"
     CDS             1..404
                     /gene="ifngr1l"
                     /coded_by="NM_001360849.1:173..1387"
                     /db_xref="GeneID:100690512"
ORIGIN      
        1 mdsfhavfly fscmtvvasr vlppmnvtlh crnfhnvlkw sypedttgls frlnigayqn
       61 ppdirtwnts alqadlsfls dpndsyyvav tavvngsese papsedgitf syfhenpvet
      121 kcyldlppvn vtaqrdnkvq isfvnpsvfy cekmkknkkk clkdngskds sfkvkilnqt
      181 hsftceervc entlpvdaaq pehcvnitgq tsqgtlvkak qlycakpfhe psqsnftavy
      241 vvsailavat fgvilfmayq kltkptnsii kiwefpksls rpmntpesvt vdhvecskrc
      301 devepssptp llsqteeedg trftnydsrf pirvshngdm snvmeeeqpn gegpgymvgn
      361 tdlhedpdsg denpgsgyek rdtvavelgp delakgyrgp vape
//
LOCUS       NP_001269821            1342 aa            linear   VRT 18-JUN-2025
DEFINITION  aldehyde oxidase 6 [Oreochromis niloticus].
ACCESSION   NP_001269821
VERSION     NP_001269821.1
DBSOURCE    REFSEQ: accession NM_001282892.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 1342)
  AUTHORS   Kurosaki,M., Bolis,M., Fratelli,M., Barzago,M.M., Pattini,L.,
            Perretta,G., Terao,M. and Garattini,E.
  TITLE     Structure and evolution of vertebrate aldehyde oxidases: from gene
            duplication to gene suppression
  JOURNAL   Cell Mol Life Sci 70 (10), 1807-1830 (2013)
   PUBMED   23263164
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BK008650.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK008650.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMN07788113, SAMN07788116
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1342
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG23"
                     /linkage_group="LG23"
     Protein         1..1342
                     /product="aldehyde oxidase 6"
                     /EC_number="1.2.3.1"
                     /note="aldehyde oxidase beta; aldehyde oxidase 1"
                     /calculated_mol_wt=146774
     Region          10..1342
                     /region_name="mam_aldehyde_ox"
                     /note="aldehyde oxidase; TIGR02969"
                     /db_xref="CDD:132014"
     CDS             1..1342
                     /gene="aox6"
                     /gene_synonym="aox1"
                     /coded_by="NM_001282892.1:1..4029"
                     /db_xref="GeneID:100708434"
ORIGIN      
        1 msagkqgdal cffingkrvt enhadpetml lpflrekvkl tgtkygcggg gcgactvmvs
       61 ryqpatktii hysanacllp lcqlhgaavt tvegigstkt rihpvqeria kahgsqcgfc
      121 tpgmvmstya llrnkpqptm dditealagn lcrctgyrpi vegcrtfcqe anccqangaa
      181 ncclngekng depeqekpql fdkldllpld ptqelifppe lilmadtspq tltfhgervs
      241 wvspvsleel iqlkakhpka plvmgntnig pdmkfkgilh pliisptrvk elfevsqtpq
      301 gvwvgagcsl selhsvlkkl vpqfpeekte vfralnrqlg nlgsvqirnv aslggnivsa
      361 ypnsdlnpil avgnckvsvi ssggrrevpl nqdffvgfgk vilqpeeivv svfipfsrkg
      421 efvqalrhap rkeasfatvt agmrvmfses srvvqdisiy yggmgpttvs aaktcqaiir
      481 rpwddetlgq aydilleela lppsapggkv efrrsltlsl lfkfylevlh klkamnvitd
      541 evpekiqplp reiqpglqef qpvskdqgnh davgrpmmhr saisqatgea vycddlpkie
      601 gelflvvvts srahakitgl dvsealqlpg vvdvittkdi pgkkvrtfcg ydeellaese
      661 vscigqmica vvadtkahak rgaaavkisy edlpdpifti eeavekssyf eprrllqrgd
      721 vteafktvdk vyegeirigg qehfymetqs mlvvpvgeem efnvyistqw ptliqdavae
      781 tlnissnrvt chvkrvggaf ggkvtrtsvl asitsvaawk tnravrcvle rgedmvitgg
      841 rhptlgkykv gfmndgkiva adiqffansg ntvdesplva ekmvlhmdna ynipnlrgrg
      901 aacktnlpsn tafrgfgvpq sllivenmin dvamvlgcpa dkvplhpllp qarprevnmy
      961 rgpstthykf efnpenllrc weegkrrsdy sarraaieqf nqqnrwkkrg isiipikygi
     1021 afsdgflnqa aalvhiykdg svlvshggte igqgvhtkmq qvasrelhip pskiyisets
     1081 tntvpntcps aasfgtdang mavkdacqil yqrlepirkk npkgtweswa keafmekisl
     1141 satgfykgpd lyldwdkmeg qpyayytygv scseveldcl tgdyrtlrtd ivmdigksvn
     1201 psvdvgqieg aftqglglyt leelkfspfg llytrgpsqy kipavcdmpl qlniyllpds
     1261 enpyaiyssk gigepalflg ssvffaikda vaaarsdsgl kgpfslnspa tperaclasa
     1321 spftqkvpas kpgsfkpwal di
//
LOCUS       NP_001364345            2192 aa            linear   VRT 18-JUN-2025
DEFINITION  lysine-specific demethylase 6B [Oreochromis niloticus].
ACCESSION   NP_001364345
VERSION     NP_001364345.1
DBSOURCE    REFSEQ: accession NM_001377416.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 2192)
  AUTHORS   Zhang,R., Zhang,L.L., Ye,X., Tian,Y.Y., Sun,C.F., Lu,M.X. and
            Bai,J.J.
  TITLE     Transcriptome profiling and digital gene expression analysis of
            Nile tilapia (Oreochromis niloticus) infected by Streptococcus
            agalactiae
  JOURNAL   Mol Biol Rep 40 (10), 5657-5668 (2013)
   PUBMED   24068429
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            MKQE02000003.1 and GBCP01051455.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2482243,
                              SAMEA2482244 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2192
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG3"
                     /linkage_group="LG3"
     Protein         1..2192
                     /product="lysine-specific demethylase 6B"
                     /EC_number="1.14.11.68"
                     /note="lysine demethylase 6B"
                     /calculated_mol_wt=245927
     Region          <167..721
                     /region_name="PHA03247"
                     /note="large tegument protein UL36; Provisional"
                     /db_xref="CDD:223021"
     Region          <220..416
                     /region_name="DUF5585"
                     /note="Family of unknown function (DUF5585); pfam17823"
                     /db_xref="CDD:465521"
     Region          1894..1958
                     /region_name="JmjC"
                     /note="A domain family that is part of the cupin
                     metalloenzyme superfamily; smart00558"
                     /db_xref="CDD:214721"
     Region          1928..2036
                     /region_name="JmjC"
                     /note="JmjC domain, hydroxylase; pfam02373"
                     /db_xref="CDD:396791"
     CDS             1..2192
                     /gene="kdm6ba"
                     /coded_by="NM_001377416.1:634..7212"
                     /db_xref="GeneID:100712234"
ORIGIN      
        1 mhhpveqfgg rgtrdsfpld elnrgpwppv ggrawqppar csptmnqhql lphlppgpmg
       61 glnhhskyfs ngpmrgsekl dlpqpmlppl qreqqrpphh lhppphhraw eisqlydshl
      121 pprghpvmpl pndlslrlhn ggyggsggpp pnphfpsrgp nhmlkfggpq epnvprgppl
      181 lgddmwaqvh qqrpypgkmq ggqlkrpgpp lgehsviqht pspslhtpsq staeecpsps
      241 krkkssdqvs hpglqrfsga gqslpqqqss aqhhppkpaf wnpihkdssv pwqpqtserk
      301 npqshefqen nkqgmgsytq rsspaslaps nlaplpnspp gsynqgcapk iqkdklqpqa
      361 vnhrsphssy pspgskpesa ppsqaketrg pqmqrgplig gqggsqatsh tastptrgdr
      421 dhhrhaqssp anvsatgsnn ssssvpyshf qphpglvhqg ppppppqass tsvpqqqqsg
      481 pheawryqst psnhslesgs yrppgllpqc qqshnqvvds rhpgssrhqh hvspplpptr
      541 tpvittnppm sqtpcsvsrh sngsgsnrva maassavats ppagcsvnnd stsnrwqggr
      601 epapqtptsa vinskshrda lqqpgnhrgp aptanqshqh gatksqhmkg kmayyaqaql
      661 ekppfsssss lfssgqnrag dsvitstvss plsnsptycp vshstvssap qpsspalpsk
      721 qmfshpqtpt svpqsieeal dkldaelegh mqaeerrkle reeqerkrre kerekrewem
      781 rqkqeeerkr ielekkeeer krelekqeee nrrreqerqe qerrkeeerr rieverleke
      841 rkrrewekqe eerkrrewek erkrrewekq eeerkrrewe kqqeeekrrr eaerheqerk
      901 kreleweeee kkkqkelerk eeekkrmern rddklcsakg keqaaienle rllcentspv
      961 ppppplssvt aspsgpspps aqasppypwl srggvlpcqs gqtpaaaava ahverlrppp
     1021 ltpqtdyare kqrqremwsn nggltfspss tnntsgmnqp vypnkppamq aapsqskdpa
     1081 rerdssqhsl ptvalreppk lyhafsrenl pplsststgg ilnkqmtrgg levadsdsaq
     1141 feeessestl lpdglanima mldesikkee emynsekngp aglidtfsps aepsknylca
     1201 pdlvpatkhq pshedrsnas ppvlsrqgsl aspcsrtssl neddedylkp spnnpkrhvd
     1261 mpmgigntny rhsdlaklyg lpeqiksdpd ededeedsea pscspppqrp hlhqtgvnsm
     1321 fkslatvles qkyayrggpf grpppsalvg vkyssslslg pdiccqqqss sptsdstnpp
     1381 fspavppiks sprslledkk lkledsdvwt degdseegit fikkksipti kpirpmkeeq
     1441 elttisessl aelgkscevm lsrqslhyks syekhdsqgq mgnrhkpekv rehrekgrsr
     1501 drqrdkekkr khghsssrkh edrkekkkhr dkkdssssth sssshkrhkd gkshkekdrr
     1561 ilsdlnlqrk egsektfgly etekrkckea sgtsstsege rrewtsstge rssehkkges
     1621 gsslgstdlm klkalsdgpp kelkirlikv esgdretfia seveekripl kdisikntas
     1681 eiirsckaar lkgkfkesyl lpafsvkpii sreepiprek lnpptpsiyl eskrdafspv
     1741 llqfctdskn pvtvirglag slrlnlglfs tkslveanad qmvevrtqvq qpadenwdps
     1801 gtgqtwpces srshttiaky aqyqassfqe slqeekgsde eddeddekkp pnssetpnkd
     1861 ssketcngeq kpvgkiikfg tnidlsdpkr wkpqlqelqk lpafmrvsss gnmlthvght
     1921 ilgmnsvqly mkvpgsrtpg hqennnfcsv ninigpgdce wfcvhdnywq aisdfcekhg
     1981 vdyltgswwp vledlynani pvyrfiqrpg dlvwinagtv hwvqavgwcn niawnvgpln
     2041 gyqyqlaler fewnevkkvk sivpmihvsw nvartlkttd pdtykmikhc lmqsmkhiqi
     2101 lrdqlvgegk kisyqsrvkd epayycnecd vevfnllfvt sennsrktyv vhcedcarrr
     2161 npsltnvvvl eqyrieelmn vydsftlass sr
//
LOCUS       NP_001266504             526 aa            linear   VRT 18-JUN-2025
DEFINITION  cytochrome P450 1C1 [Oreochromis niloticus].
ACCESSION   NP_001266504 XP_003447788
VERSION     NP_001266504.1
DBSOURCE    REFSEQ: accession NM_001279575.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 526)
  AUTHORS   Hassanin,A.A., Kaminishi,Y., Funahashi,A. and Itakura,T.
  TITLE     Cytochrome P450 1C1 complementary DNA cloning, sequence analysis
            and constitutive expression induced by benzo-a-pyrene in Nile
            tilapia (Oreochromis niloticus)
  JOURNAL   Aquat Toxicol 109, 17-24 (2012)
   PUBMED   22204985
  REMARK    GeneRIF: Oreochromis niloticus
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from HQ829969.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003447788.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: HQ829969.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG19"
                     /linkage_group="LG19"
     Protein         1..526
                     /product="cytochrome P450 1C1"
                     /EC_number="1.14.14.1"
                     /calculated_mol_wt=59406
     Region          82..511
                     /region_name="CYP1B1-like"
                     /note="cytochrome P450 family 1, subfamily B, polypeptide
                     1 and similar cytochrome P450s; cd20675"
                     /db_xref="CDD:410768"
     Site            order(118,133..134,142,146,153,320,323..324,327..328,
                     387..388,391..392,394,417,455..457,461,463..465,469)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:410768"
     Site            order(127..128,132,134..135,229,232,265..266,269,319,
                     322..323,326..327,388,392,502..503)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:410768"
     CDS             1..526
                     /gene="cyp1c1"
                     /coded_by="NM_001279575.1:1..1581"
                     /db_xref="GeneID:100653402"
ORIGIN      
        1 maldtefgvk ssssiirews gqvhpalvat fvflfcveac lwvrnlrlkr rlpgpfawpv
       61 vgnamqlgqm phitfarlak kygnvyqirl gcsdvvvlng erairqaliq hstefagrpn
      121 flsfqmisgg rsltftnysk qwkahrkvaq sslrafssan shtkkafeqh vtaeamelvq
      181 allrqstdrr ysdlvheftv asanimcalc fgrryghddl efrtllkrmd kfgetvgags
      241 lvdvmpwlqs fpnpvrsvye nfknineeff gfvkdkvmqh resfnpqvtr dmsdaiisvi
      301 ehgedsrltk efveatvtdl igagqdtist fmqwillllv kypdvqaklq elidkvvgrd
      361 rlpsiedrss layldafiye tmrfislvpl tiphsttsdv tieglhipkd tvvfinqwsv
      421 nhdplkwkdp hvfdpsrfld esgaldkdka nsvmifstgk rrcignqiak vevfiftavl
      481 lhqcsfesnp sepvtldcsy glalkplpfr vstklrrkll glvspa
//
LOCUS       NP_001337509             451 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform b [Homo
            sapiens].
ACCESSION   NP_001337509
VERSION     NP_001337509.1
DBSOURCE    REFSEQ: accession NM_001350580.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 451)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 451)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 451)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 451)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 451)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 451)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 451)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 451)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 451)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 451)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038193.4152299.1,
                                           SRR14038192.1908967.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..451
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform b"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=51991
     Region          185..374
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..451
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350580.2:12..1367"
                     /note="isoform b is encoded by transcript variant 2"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 malsctlnry lllmaqehle frlpfassqe tygkspfwil sipsediarn lmkrtvcaks
       61 ifelwghgqs peelysslkn ypvekmvpfl hsdstykiki htfnktltqe ekikridale
      121 flpfegkvnl kkpqhvfsvl edygldpnci penphniyfg rwiadgqrel iesysvkkrh
      181 figntsmdag lsfimanhgk vkendivfdp fvgtggllia cahfgayvyg tdidyntvhg
      241 lgkatrknqk wrgpdenira nlrqygleky yldvlvsdas kpswrkgtyf daiitdppyg
      301 irestrrtgs qkeipkgiek wekcpeshvp vslsyhlsdm fldllnfaae tlvlggrlvy
      361 wlpvytpeyt eemvpwhpcl elvsnceqkl sshtsrrlit mekvkkfenr dqyshllsdh
      421 flpyqghnsf rekyfsgvtk riakeekstq e
//
LOCUS       NP_001266373            1447 aa            linear   VRT 18-JUN-2025
DEFINITION  collagen, type I, alpha 1a precursor [Oreochromis niloticus].
ACCESSION   NP_001266373 XP_003446446 XP_003446447
VERSION     NP_001266373.1
DBSOURCE    REFSEQ: accession NM_001279444.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB603656.1.
            
            On or before Jul 22, 2013 this sequence version replaced
            XP_003446446.1, XP_003446447.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB603656.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4513697, SAMN03013320
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1447
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG4"
                     /linkage_group="LG4"
     Protein         1..1447
                     /product="collagen, type I, alpha 1a precursor"
                     /note="collagen type I alpha 1 chain"
                     /calculated_mol_wt=134883
     sig_peptide     1..22
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2419
     Region          33..88
                     /region_name="VWC"
                     /note="von Willebrand factor (vWF) type C domain;
                     smart00214"
                     /db_xref="CDD:214564"
     Region          <90..>292
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          <216..>534
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          <424..>724
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          <614..857
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          <742..>1017
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          <949..>1138
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          1210..1446
                     /region_name="COLFI"
                     /note="Fibrillar collagen C-terminal domain; pfam01410"
                     /db_xref="CDD:460199"
     CDS             1..1447
                     /gene="col1a1a"
                     /gene_synonym="col1a1"
                     /coded_by="NM_001279444.1:158..4501"
                     /db_xref="GeneID:100702721"
ORIGIN      
        1 mfsfvdlrla lllsaavllv raqgeddrtg ksctldgqvf adrdvwkpep cqicvcdsgt
       61 vmcdeviced ttdcpnpiip hdeccpicpd dgfqepqteg tvgargpkgd rglpgppgrd
      121 gmpgqpglpg ppgppgppgl ggnfspqmsg gydekspamp vpgpmgpmgp rgppgppgss
      181 gpqgftgppg eagepgspgp mgprgpagpp gkngedgesg kpgrpgergp pgpqgargfp
      241 gtpglpgikg hrgfsgldga kgdtgpagpk geagtpgeng tpgamgprgl pgergragat
      301 gaagargndg aagaagppgp tgpagppgfp ggpgakgdag aqggrgpegp agargepgnp
      361 gpagpagpag npgsdgapga kgapgaagva gapgfpgprg psgpqgaaga pgpkgntgea
      421 gapgskgeag akgeagapgv qgppgppgee gkrgargepg aagarggpge rgapggrgfp
      481 gsdgpagpkg atgergapgl vgpkgatgep grtgepglpg akgmtgspgn pgpdgkigps
      541 gapgqdgrpg ppgpggargq pgvmgfpgpk gaageagkpg ergtmgptgp agapgkdgdv
      601 gaqgppgpag pagergeqgp agspgfqglp gpqgavgetg kpgeqgvpge agapgpagar
      661 gdrgfpgerg apgaigpaga rgspgasgnd gakgdagapg tpgaqgppgl qgmpgergaa
      721 glpglrgnrg dqgpkgadgt pgkdgprglt gpiglpgpag spgdkgepga qgpvgpsgar
      781 gppgergeag ppgpagfagp pgadgqpgak gepgdngakg dsgppgpagp tgapgpqgpv
      841 gntgpkgarg pagppgatgf pgaagrvgpp gpagnagppg ppgpagkegp kgnrgetgpa
      901 grpgelgaag ppgppgekgs pgadgapgsa gipgpqgiag qrgivglpgq rgergfpgla
      961 gpvgepgkqg psgpsgergp pgpmgppgla gapgepgreg tpgnegaagr dgapgpkgdr
     1021 gesgpagapg apgppgapgp vgpagktgdr getgpagpag aagpagprgp agapglrgdk
     1081 getgeagerg mkghrgftgm qgppgppgts gesgpagaag pagprgpsga agapgkdgvs
     1141 glpgptgppg prgrsgemgp agppgppgpp gapgapgggf dlgfmvqpqe kapdpfrmyr
     1201 addanvlrdr dlevdstlks lsqqieqirs pdgtrknpar tcrdlkmchp dwksgeywid
     1261 pdqgctqdai kvycnmetge tcvsptqrev akknwyiskn ikekkhvwfg eamnegfqfe
     1321 ygsegslped vniqmtflrl msteasqnit yhcknsvaym daaagnlkka lllqgsneie
     1381 iraegnsrft ysvledgcts htgtwgktvi dyktsktsrl piidiapmdv gapdqefgfe
     1441 vgpvcfl
//
LOCUS       NP_001266696             469 aa            linear   VRT 18-JUN-2025
DEFINITION  doublesex- and mab-3-related transcription factor 2a [Oreochromis
            niloticus].
ACCESSION   NP_001266696 XP_003444526
VERSION     NP_001266696.1
DBSOURCE    REFSEQ: accession NM_001279767.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY149606.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003444526.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY149606.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767855, SAMN00767858
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG12"
                     /linkage_group="LG12"
     Protein         1..469
                     /product="doublesex- and mab-3-related transcription
                     factor 2a"
                     /note="DM-related transcriptional factor Dmrt2; doublesex
                     and mab-3 related transcription factor 2"
                     /calculated_mol_wt=52026
     Region          11..57
                     /region_name="DM"
                     /note="DM DNA binding domain; pfam00751"
                     /db_xref="CDD:459924"
     CDS             1..469
                     /gene="dmrt2a"
                     /gene_synonym="dmrt2"
                     /coded_by="NM_001279767.1:121..1530"
                     /db_xref="GeneID:100534511"
ORIGIN      
        1 mcagdqrkls rtpkcarcrn hgvvsclkgh krfcrwrdcq cancllvver qrvmaaqval
       61 rrqqatedkk gisgkpipae rrtiyqrhir pstmlaksil eryrpvqsdp flaanpslpp
      121 plsdrmrkrr afadkeleti mlereykere lmennqgapg sllfpnglvh hsseynsyks
      181 ayspaapvep qpkelcsflt pncldlsmqy pstpgnveli ssnvsvatty rhyplqpsrg
      241 gfvmwprgaa nlgdallyqq clfnatavqn mkpgavwepk ampaesqppe qeaaaalaak
      301 legsraaalq dlsdpqrpdp kppaitqgeq recsafsppk rsfgqsfpnh phsqnssqvl
      361 nklskdnakp smklnsfhsl iqhslsekas ggsgpelrap yckelleeaa rkyressakd
      421 fqavkltdry akdflskpvg tkmapsesls fsveailkrp tpaisrafh
//
LOCUS       NP_001161337             384 aa            linear   PRI 18-JUN-2025
DEFINITION  non-structural maintenance of chromosomes element 4 homolog A
            isoform 2 [Homo sapiens].
ACCESSION   NP_001161337
VERSION     NP_001161337.1
DBSOURCE    REFSEQ: accession NM_001167865.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 384)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (residues 1 to 384)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (residues 1 to 384)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   4  (residues 1 to 384)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   5  (residues 1 to 384)
  AUTHORS   van der Crabben,S.N., Hennus,M.P., McGregor,G.A., Ritter,D.I.,
            Nagamani,S.C., Wells,O.S., Harakalova,M., Chinn,I.K., Alt,A.,
            Vondrova,L., Hochstenbach,R., van Montfrans,J.M.,
            Terheggen-Lagro,S.W., van Lieshout,S., van Roosmalen,M.J.,
            Renkens,I., Duran,K., Nijman,I.J., Kloosterman,W.P., Hennekam,E.,
            Orange,J.S., van Hasselt,P.M., Wheeler,D.A., Palecek,J.J.,
            Lehmann,A.R., Oliver,A.W., Pearl,L.H., Plon,S.E., Murray,J.M. and
            van Haaften,G.
  TITLE     Destabilized SMC5/6 complex leads to chromosome breakage syndrome
            with severe lung disease
  JOURNAL   J Clin Invest 126 (8), 2881-2892 (2016)
   PUBMED   27427983
REFERENCE   6  (residues 1 to 384)
  AUTHORS   Doyle,J.M., Gao,J., Wang,J., Yang,M. and Potts,P.R.
  TITLE     MAGE-RING protein complexes comprise a family of E3 ubiquitin
            ligases
  JOURNAL   Mol Cell 39 (6), 963-974 (2010)
   PUBMED   20864041
REFERENCE   7  (residues 1 to 384)
  AUTHORS   Taylor,E.M., Copsey,A.C., Hudson,J.J., Vidot,S. and Lehmann,A.R.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   8  (residues 1 to 384)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   9  (residues 1 to 384)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   10 (residues 1 to 384)
  AUTHORS   Hu,B., Liao,C., Millson,S.H., Mollapour,M., Prodromou,C.,
            Pearl,L.H., Piper,P.W. and Panaretou,B.
  TITLE     Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex
  JOURNAL   Mol Microbiol 55 (6), 1735-1750 (2005)
   PUBMED   15752197
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC062427.1 and AL731566.7.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the coding region, compared to variant 1. This
            results in a shorter protein (isoform 2), compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062427.1, SRR14038191.546868.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.13"
     Protein         1..384
                     /product="non-structural maintenance of chromosomes
                     element 4 homolog A isoform 2"
                     /note="non-structural maintenance of chromosomes element 4
                     homolog A; non-SMC element 4 homolog A; NSE4 homolog A,
                     SMC5-SMC6 complex component; NSE4 homolog, SMC5-SMC6
                     complex component A"
                     /calculated_mol_wt=44041
     Region          1..69
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NXX6.2)"
     Region          133..187
                     /region_name="Nse4-Nse3_bdg"
                     /note="Binding domain of Nse4/EID3 to Nse3-MAGE;
                     pfam15412"
                     /db_xref="CDD:464708"
     Region          285..373
                     /region_name="Nse4_C"
                     /note="Nse4 C-terminal; pfam08743"
                     /db_xref="CDD:462585"
     Site            345
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:17525332; propagated from
                     UniProtKB/Swiss-Prot (Q9NXX6.2)"
     Site            376
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17525332; propagated from
                     UniProtKB/Swiss-Prot (Q9NXX6.2)"
     CDS             1..384
                     /gene="NSMCE4A"
                     /gene_synonym="C10orf86; NS4EA; NSE4A"
                     /coded_by="NM_001167865.2:53..1207"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:54780"
                     /db_xref="HGNC:HGNC:25935"
                     /db_xref="MIM:612987"
ORIGIN      
        1 msgdssgrgp egrgrgrdph rdrtrsrsrs rsplsprsrr gsarerreap erpsledtep
       61 sdsgdemmdp asleaeadqg lcrqirhqyr alinsvqqnr edilnagdkl tevleeantl
      121 fnevsrarea vldahflvla sdlgkekakq lrsdlssfdm lryvetllth mgvnpleaee
      181 lirdedspdf efivydswki tgrtaentfn kthtfhfllg siygecpvpk prvdrprkvp
      241 viqeerampa qlrrmeeshq eatekeveri lgllqtyfre dpdtpmsffd fvvdphsfpr
      301 tvenifhvsf iirdgfarir ldqdrlpvie pvsineeneg fehntqvrnq giialsyrdw
      361 eivktfeise pvitpsqrqq kpsa
//
LOCUS       NP_001337510             400 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform c [Homo
            sapiens].
ACCESSION   NP_001337510
VERSION     NP_001337510.1
DBSOURCE    REFSEQ: accession NM_001350581.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 400)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 400)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 400)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 400)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 400)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 400)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 400)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 400)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 400)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 400)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (3), as well as variants 4-6,
            encodes isoform c.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.1213148.1,
                                           SRR14038195.133125.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..400
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform c"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=46106
     Region          134..323
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..400
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350581.2:352..1554"
                     /note="isoform c is encoded by transcript variant 3"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mkrtvcaksi felwghgqsp eelysslkny pvekmvpflh sdstykikih tfnktltqee
       61 kikridalef lpfegkvnlk kpqhvfsvle dygldpncip enphniyfgr wiadgqreli
      121 esysvkkrhf igntsmdagl sfimanhgkv kendivfdpf vgtgglliac ahfgayvygt
      181 didyntvhgl gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask pswrkgtyfd
      241 aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf ldllnfaaet
      301 lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm ekvkkfenrd
      361 qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001333843             642 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein 429 isoform c [Homo sapiens].
ACCESSION   NP_001333843 XP_016882240
VERSION     NP_001333843.1
DBSOURCE    REFSEQ: accession NM_001346914.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 642)
  AUTHORS   Kim,H., Ramsay,E., Lee,H., Wahl,S. and Dionne,R.A.
  TITLE     Genome-wide association study of acute post-surgical pain in humans
  JOURNAL   Pharmacogenomics 10 (2), 171-179 (2009)
   PUBMED   19207018
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   2  (residues 1 to 642)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010615.9.
            
            On Nov 8, 2016 this sequence version replaced XP_016882240.1.
            
            Transcript Variant: This variant (4), as well as variants 3 and 5,
            encodes isoform c.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.178667.1,
                                           SRR1660803.211445.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144335, SAMEA2145240
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     Protein         1..642
                     /product="zinc finger protein 429 isoform c"
                     /calculated_mol_wt=74306
     Region          <1..31
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          115..135
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          143..163
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          171..191
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          197..592
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          199..219
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          227..247
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          255..275
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          283..303
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(288,290,292,294..295,298..299,302,316,318,322..323,
                     326..327,330,344,346,348,350..351,354..355,358)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          311..331
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          339..359
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          370..387
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          395..415
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(400,402,404,406..407,410..411,414,428,430,434..435,
                     438..439,442,456,458,460,462..463,466..467,470)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          423..443
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          451..471
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          479..499
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          507..527
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(512,514,516,518..519,522..523,526,540,542,546..547,
                     550..551,554,568,570,572,574..575,578..579,582)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          535..555
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          563..583
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          591..611
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..642
                     /gene="ZNF429"
                     /coded_by="NM_001346914.2:573..2501"
                     /note="isoform c is encoded by transcript variant 4"
                     /db_xref="GeneID:353088"
                     /db_xref="HGNC:HGNC:20817"
                     /db_xref="MIM:621242"
ORIGIN      
        1 mlenyrnlvf lgiavskpdl itclekekep ckmkrhemvd eppvvcshfa edfwpeqdik
       61 dsfqkvtlrr ydkrghenlq lrkgyktvgd cklykggyng lnqcltltqs kmyhcdiyvk
      121 vfyafsnadr yktrhtgkkp fqckkcgksf cmlsqltqhk kihirentyr ckefgnafnq
      181 ssaltnhkri yvgekhyrce ecgkafnhys tltnhkriht gekpykckec gkafsrystl
      241 tthkrihsge kpykcdecgk tfsisstftk hkiihteekp ykckecgkaf nrsstltshk
      301 rihtgekpyk ceecgkafnw sstltkhkvi htgekpykce ecgkafnqss rltrhkkiht
      361 geepykfekc grvftcsstl tqdkkihtge kpynceecgk vftysstltr hkrihteekp
      421 ykcnecgkaf nrsshltshr rihtgekpyk ceecgkafkq ssnlnshkki hsgekpykce
      481 ecgkafilss rltqhkkiht gekpykceec gkafnrssrl tqhkkihtge kpykckqcdk
      541 afthssnlss hkkihsgekp ykceecgkaf nrssrltqhk kihtrekpyk ceecakaftr
      601 ssrltqhkki hrmgvvahac npstlggrgg ritrsgdrdr pg
//
LOCUS       NP_001266515             522 aa            linear   VRT 18-JUN-2025
DEFINITION  aromatase [Oreochromis niloticus].
ACCESSION   NP_001266515 XP_003458233
VERSION     NP_001266515.1
DBSOURCE    REFSEQ: accession NM_001279586.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 522)
  AUTHORS   Wang,Y.Y., Sun,L.X., Zhu,J.J., Zhao,Y., Wang,H., Liu,H.J. and
            Ji,X.S.
  TITLE     Epigenetic control of cyp19a1a expression is critical for high
            temperature induced Nile tilapia masculinization
  JOURNAL   J Therm Biol 69, 76-84 (2017)
   PUBMED   29037408
  REMARK    GeneRIF: The increases in the cyp19a1a promoter DNA methylation
            levels were associated with the mRNA expression levels and might
            play a role in promoting gonadal differentiation in high
            temperature induced group females toward the male pathway. Western
            blot analysis revealed that the cyp19a1a protein expression levels
            in females significantly declined after high temperature treatment.
REFERENCE   2  (residues 1 to 522)
  AUTHORS   Chang,X.T., Kobayashi,T., Kajiura,H., Nakamura,M. and Nagahama,Y.
  TITLE     Isolation and characterization of the cDNA encoding the tilapia
            (Oreochromis niloticus) cytochrome P450 aromatase (P450arom):
            changes in P450arom mRNA, protein and enzyme activity in ovarian
            follicles during oogenesis
  JOURNAL   J Mol Endocrinol 18 (1), 57-66 (1997)
   PUBMED   9061607
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U72071.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003458233.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U72071.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767858, SAMN01086111
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG1"
                     /linkage_group="LG1"
     Protein         1..522
                     /product="aromatase"
                     /EC_number="1.14.14.14"
                     /function="catalyzes estrogen production from
                     testosterone"
                     /note="Estrogen synthase; Cytochrome P-450AROM; Cytochrome
                     P450 19A1; cytochrome P450 aromatase type I; aromatase
                     ovarian form"
                     /calculated_mol_wt=59297
     Region          86..495
                     /region_name="CYP19A1"
                     /note="cytochrome P450 family 19, subfamily A, polypeptide
                     1; cd20616"
                     /db_xref="CDD:410709"
     Site            order(121,129,146..147,155,159,166,315,319..320,373,379,
                     382,384,439..441,445..449,456..457)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:410709"
     Site            order(129,147..148,234,314..315,318..319,379,381..383,487)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:410709"
     CDS             1..522
                     /gene="cyp19a1a"
                     /gene_synonym="Aromatase; cyp19; cyp19a1; CYPXIX"
                     /coded_by="NM_001279586.1:34..1602"
                     /db_xref="GeneID:100708217"
ORIGIN      
        1 mdlisaceqa mnpvgldavv arslcdlkch pidgismatr tlillvclll vawshtdkki
       61 vpgpsfclgl gpllsylrfi wtgigtasny ynnkygdivr vwingeetli lsrssavhhv
      121 lkngnytsrf gsiqglsylg mnergiifnn nvtlwkkirt yfakaltgpn lqqtvdvcvs
      181 siqahldhld slghvdvlnl lrctvldisn rlflnvplne kelmlkiqky fhtwqdvlik
      241 pdiyfkfrwi hhrhktatqe lqdaikrlvd qkrknmeqad kldninftae lifaqnhgel
      301 saenvtqcvl emviaapdtl slslffmlll lkqnphvepq llqeidavvg erqlqnqdlh
      361 klqvmesfiy eclsfhpvvd ftmrralsdd iiegyriskg tniilntgrm hrtefflkgn
      421 qfnlehfenn vprpptfqpf gsgpracigk hmamvmmksi lvtllsqysv cthegpildc
      481 lpqtnnlsqq pvehqqaete hlhmrflprq gsscqtlkdp nl
//
LOCUS       NP_001266711             468 aa            linear   VRT 18-JUN-2025
DEFINITION  dopamine receptor D2a [Oreochromis niloticus].
ACCESSION   NP_001266711 XP_003450871
VERSION     NP_001266711.1
DBSOURCE    REFSEQ: accession NM_001279782.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 468)
  AUTHORS   Levavi-Sivan,B., Aizen,J. and Avitan,A.
  TITLE     Cloning, characterization and expression of the D2 dopamine
            receptor from the tilapia pituitary
  JOURNAL   Mol Cell Endocrinol 236 (1-2), 17-30 (2005)
   PUBMED   15876479
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY673985.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003450871.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY673985.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG14"
                     /linkage_group="LG14"
     Protein         1..468
                     /product="dopamine receptor D2a"
                     /note="dopamine receptor D2"
                     /calculated_mol_wt=52460
     Region          33..462
                     /region_name="7tmA_D2_dopamine_R"
                     /note="D2 subtype of the D2-like family of dopamine
                     receptors, member of the class A family of
                     seven-transmembrane G protein-coupled receptors; cd15309"
                     /db_xref="CDD:320435"
     Region          34..60
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320435"
     Region          67..90
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320435"
     Region          105..135
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320435"
     Site            order(108,112..113,116,191,194..195,413..414,417,433,437,
                     441)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:320435"
     Region          150..168
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320435"
     Region          187..212
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320435"
     Region          390..420
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320435"
     Region          430..455
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320435"
     CDS             1..468
                     /gene="drd2a"
                     /gene_synonym="drd2"
                     /coded_by="NM_001279782.1:167..1573"
                     /db_xref="GeneID:100534521"
ORIGIN      
        1 mdvftqyayn dsfydngtwg fndtdqeqkh pynyyamllt llifvivfgn vlvcmavsre
       61 kalqtttnyl ivslavadll vatlvmpwvv ylevvgewrf skihcdifvt ldvmmctasi
      121 lnlcaisidr ytavampmly ntryssrrrv tvmisvvwvl sfaiscpllf glnntatrde
      181 slcvianpaf vvyssivsfy vpfiitllvy vqiyvvlrkr rkrvntkpkq rvsqaadpdv
      241 atslkdkcth pedvrlctmi vktngsfpvn kkkvifikdv vnegedleld elnnsgssak
      301 qkqqiqcalg dtpatshqll mpnrasaspi stpptphkeg qkaekngdpa setlgnpapi
      361 vakafqtqal pngktqtsvk tmskrkisqq kekkatqmla ivlgvfiicw lpffithiln
      421 thctkckvpa emynaftwlg yvnsavnpii yttfnvefrk afikilhc
//
LOCUS       NP_001352808             261 aa            linear   VRT 18-JUN-2025
DEFINITION  iodothyronine deiodinase 3a [Oreochromis niloticus].
ACCESSION   NP_001352808 XP_013131844
VERSION     NP_001352808.1
DBSOURCE    REFSEQ: accession NM_001365879.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            MKQE02000019.1.
            
            On Sep 13, 2018 this sequence version replaced XP_013131844.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: GBCP01113010.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            protein contains selenocysteine :: inferred from conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG19"
                     /linkage_group="LG19"
     Protein         1..261
                     /product="iodothyronine deiodinase 3a"
                     /EC_number="1.21.99.3"
                     /note="type IIIa iodothyronine deiodinase"
                     /calculated_mol_wt=29897
     Region          11..247
                     /region_name="Protein Disulfide Oxidoreductases and Other
                     Proteins with a Thioredoxin fold"
                     /note="The thioredoxin (TRX)-like superfamily is a large,
                     diverse group of proteins containing a TRX fold. Many
                     members contain a classic TRX domain with a redox active
                     CXXC motif. They function as protein disulfide
                     oxidoreductases (PDOs), altering the redox...; cl00388"
                     /db_xref="CDD:469754"
     Site            125
                     /site_type="other"
                     /note="Selenocysteine"
     CDS             1..261
                     /gene="dio3a"
                     /coded_by="NM_001365879.1:90..875"
                     /note="UGA stop codon recoded as selenocysteine"
                     /db_xref="GeneID:102082306"
ORIGIN      
        1 mntfktikna ivcfvllprf lvaavmfwll dflcirkrvf frmkeqegda idpplcisds
       61 nrlfsleslk avwhghkldf lkaahlgqva pntevvqled qrrsrildya qdkrplilnf
      121 gsctuppfma rlkafqevvr enadiadslv vyieeahpsd gwmstdapyq ipkhrcledr
      181 lnaaqlmhle vpgclvvvds menssnaayg ayfdrlyilq egkivyqggr gpegyrisel
      241 rdwlnryrdg lersnnqvih v
//
LOCUS       NP_001333842             642 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein 429 isoform c [Homo sapiens].
ACCESSION   NP_001333842 XP_016882245
VERSION     NP_001333842.1
DBSOURCE    REFSEQ: accession NM_001346913.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 642)
  AUTHORS   Kim,H., Ramsay,E., Lee,H., Wahl,S. and Dionne,R.A.
  TITLE     Genome-wide association study of acute post-surgical pain in humans
  JOURNAL   Pharmacogenomics 10 (2), 171-179 (2009)
   PUBMED   19207018
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   2  (residues 1 to 642)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010615.9.
            
            On Nov 8, 2016 this sequence version replaced XP_016882245.1.
            
            Transcript Variant: This variant (3), as well as variants 4 and 5,
            encodes isoform c.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.74294.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144335, SAMEA2145240
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     Protein         1..642
                     /product="zinc finger protein 429 isoform c"
                     /calculated_mol_wt=74306
     Region          <1..31
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          115..135
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          143..163
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          171..191
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          197..592
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          199..219
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          227..247
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          255..275
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          283..303
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(288,290,292,294..295,298..299,302,316,318,322..323,
                     326..327,330,344,346,348,350..351,354..355,358)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          311..331
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          339..359
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          370..387
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          395..415
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(400,402,404,406..407,410..411,414,428,430,434..435,
                     438..439,442,456,458,460,462..463,466..467,470)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          423..443
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          451..471
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          479..499
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          507..527
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(512,514,516,518..519,522..523,526,540,542,546..547,
                     550..551,554,568,570,572,574..575,578..579,582)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          535..555
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          563..583
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          591..611
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..642
                     /gene="ZNF429"
                     /coded_by="NM_001346913.2:363..2291"
                     /note="isoform c is encoded by transcript variant 3"
                     /db_xref="GeneID:353088"
                     /db_xref="HGNC:HGNC:20817"
                     /db_xref="MIM:621242"
ORIGIN      
        1 mlenyrnlvf lgiavskpdl itclekekep ckmkrhemvd eppvvcshfa edfwpeqdik
       61 dsfqkvtlrr ydkrghenlq lrkgyktvgd cklykggyng lnqcltltqs kmyhcdiyvk
      121 vfyafsnadr yktrhtgkkp fqckkcgksf cmlsqltqhk kihirentyr ckefgnafnq
      181 ssaltnhkri yvgekhyrce ecgkafnhys tltnhkriht gekpykckec gkafsrystl
      241 tthkrihsge kpykcdecgk tfsisstftk hkiihteekp ykckecgkaf nrsstltshk
      301 rihtgekpyk ceecgkafnw sstltkhkvi htgekpykce ecgkafnqss rltrhkkiht
      361 geepykfekc grvftcsstl tqdkkihtge kpynceecgk vftysstltr hkrihteekp
      421 ykcnecgkaf nrsshltshr rihtgekpyk ceecgkafkq ssnlnshkki hsgekpykce
      481 ecgkafilss rltqhkkiht gekpykceec gkafnrssrl tqhkkihtge kpykckqcdk
      541 afthssnlss hkkihsgekp ykceecgkaf nrssrltqhk kihtrekpyk ceecakaftr
      601 ssrltqhkki hrmgvvahac npstlggrgg ritrsgdrdr pg
//
LOCUS       NP_001001415             674 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein 429 isoform a [Homo sapiens].
ACCESSION   NP_001001415
VERSION     NP_001001415.2
DBSOURCE    REFSEQ: accession NM_001001415.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 674)
  AUTHORS   Kim,H., Ramsay,E., Lee,H., Wahl,S. and Dionne,R.A.
  TITLE     Genome-wide association study of acute post-surgical pain in humans
  JOURNAL   Pharmacogenomics 10 (2), 171-179 (2009)
   PUBMED   19207018
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   2  (residues 1 to 674)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010615.9, DA533537.1 and BM981242.1.
            
            On Oct 18, 2006 this sequence version replaced NP_001001415.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DA533537.1, SRR3476690.968948.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000358491.9/ ENSP00000351280.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..674
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     Protein         1..674
                     /product="zinc finger protein 429 isoform a"
                     /calculated_mol_wt=78022
     Region          4..63
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          147..167
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          175..195
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          203..223
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          229..624
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          231..251
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          259..279
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          287..307
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          315..335
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(320,322,324,326..327,330..331,334,348,350,354..355,
                     358..359,362,376,378,380,382..383,386..387,390)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          343..363
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          371..391
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          402..419
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          427..447
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(432,434,436,438..439,442..443,446,460,462,466..467,
                     470..471,474,488,490,492,494..495,498..499,502)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          455..475
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          483..503
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          511..531
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          539..559
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(544,546,548,550..551,554..555,558,572,574,578..579,
                     582..583,586,600,602,604,606..607,610..611,614)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          567..587
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          595..615
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            605
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:P17019; propagated from
                     UniProtKB/Swiss-Prot (Q86V71.2)"
     Region          623..643
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          653..674
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q86V71.2)"
     CDS             1..674
                     /gene="ZNF429"
                     /coded_by="NM_001001415.4:171..2195"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS42537.1"
                     /db_xref="GeneID:353088"
                     /db_xref="HGNC:HGNC:20817"
                     /db_xref="MIM:621242"
ORIGIN      
        1 mgpltftdva iefsleewqc ldtaqqnlyr nvmlenyrnl vflgiavskp dlitclekek
       61 epckmkrhem vdeppvvcsh faedfwpeqd ikdsfqkvtl rrydkrghen lqlrkgyktv
      121 gdcklykggy nglnqcltlt qskmyhcdiy vkvfyafsna dryktrhtgk kpfqckkcgk
      181 sfcmlsqltq hkkihirent yrckefgnaf nqssaltnhk riyvgekhyr ceecgkafnh
      241 ystltnhkri htgekpykck ecgkafsrys tltthkrihs gekpykcdec gktfsisstf
      301 tkhkiihtee kpykckecgk afnrsstlts hkrihtgekp ykceecgkaf nwsstltkhk
      361 vihtgekpyk ceecgkafnq ssrltrhkki htgeepykfe kcgrvftcss tltqdkkiht
      421 gekpynceec gkvftysstl trhkrihtee kpykcnecgk afnrsshlts hrrihtgekp
      481 ykceecgkaf kqssnlnshk kihsgekpyk ceecgkafil ssrltqhkki htgekpykce
      541 ecgkafnrss rltqhkkiht gekpykckqc dkafthssnl sshkkihsge kpykceecgk
      601 afnrssrltq hkkihtrekp ykceecakaf trssrltqhk kihrmgvvah acnpstlggr
      661 ggritrsgdr drpg
//
LOCUS       NP_001287978             152 aa            linear   VRT 18-JUN-2025
DEFINITION  leptin b precursor [Oreochromis niloticus].
ACCESSION   NP_001287978
VERSION     NP_001287978.1
DBSOURCE    REFSEQ: accession NM_001301049.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 152)
  AUTHORS   Shpilman,M., Hollander-Cohen,L., Ventura,T., Gertler,A. and
            Levavi-Sivan,B.
  TITLE     Production, gene structure and characterization of two orthologs of
            leptin and a leptin receptor in tilapia
  JOURNAL   Gen Comp Endocrinol 207, 74-85 (2014)
   PUBMED   24852346
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KF955989.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KF955989.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767857, SAMN00767861
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..152
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG17"
                     /linkage_group="LG17"
     Protein         1..152
                     /product="leptin b precursor"
                     /calculated_mol_wt=14833
     sig_peptide     1..18
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2009
     CDS             1..152
                     /gene="lepb"
                     /coded_by="NM_001301049.1:1..459"
                     /db_xref="GeneID:100704338"
ORIGIN      
        1 mrnilallcv flmaadqsti lltkgesikn tihnivniaq itlvhikklk lpatptevpt
       61 psidglssis hdlgvldnel qhpfliqiqa dvsslegrvr sfalsmecpl kpkpavqtde
      121 svfpdsrlym tvakvqhyle klilnkgklk lc
//
LOCUS       NP_001337513             400 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform c [Homo
            sapiens].
ACCESSION   NP_001337513
VERSION     NP_001337513.1
DBSOURCE    REFSEQ: accession NM_001350584.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 400)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 400)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 400)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 400)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 400)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 400)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 400)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 400)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 400)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 400)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (6), as well as variants 3-5,
            encodes isoform c.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074967.196801.1,
                                           SRR18074969.435930.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148093, SAMEA2149876
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..400
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform c"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=46106
     Region          134..323
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..400
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350584.2:269..1471"
                     /note="isoform c is encoded by transcript variant 6"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mkrtvcaksi felwghgqsp eelysslkny pvekmvpflh sdstykikih tfnktltqee
       61 kikridalef lpfegkvnlk kpqhvfsvle dygldpncip enphniyfgr wiadgqreli
      121 esysvkkrhf igntsmdagl sfimanhgkv kendivfdpf vgtgglliac ahfgayvygt
      181 didyntvhgl gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask pswrkgtyfd
      241 aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf ldllnfaaet
      301 lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm ekvkkfenrd
      361 qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001244923             562 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog A isoform b [Homo
            sapiens].
ACCESSION   NP_001244923
VERSION     NP_001244923.1
DBSOURCE    REFSEQ: accession NM_001257994.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 562)
  AUTHORS   Witzenberger,M., Burczyk,S., Settele,D., Mayer,W., Welp,L.M.,
            Heiss,M., Wagner,M., Monecke,T., Janowski,R., Carell,T., Urlaub,H.,
            Hauck,S.M., Voigt,A. and Niessing,D.
  TITLE     Human TRMT2A methylates tRNA and contributes to translation
            fidelity
  JOURNAL   Nucleic Acids Res 51 (16), 8691-8710 (2023)
   PUBMED   37395448
  REMARK    GeneRIF: Human TRMT2A methylates tRNA and contributes to
            translation fidelity.
REFERENCE   2  (residues 1 to 562)
  AUTHORS   Dai,W., Li,A., Yu,N.J., Nguyen,T., Leach,R.W., Wuhr,M. and
            Kleiner,R.E.
  TITLE     Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated
            dihydrouridylation
  JOURNAL   Nat Chem Biol 17 (11), 1178-1187 (2021)
   PUBMED   34556860
REFERENCE   3  (residues 1 to 562)
  AUTHORS   Pereira,M., Ribeiro,D.R., Pinheiro,M.M., Ferreira,M., Kellner,S.
            and Soares,A.R.
  TITLE     m5U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation
            of tRNA-Derived Small RNAs
  JOURNAL   Int J Mol Sci 22 (6), 2941 (2021)
   PUBMED   33799331
  REMARK    GeneRIF: m(5)U54 tRNA Hypomodification by Lack of TRMT2A Drives the
            Generation of tRNA-Derived Small RNAs.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 562)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (residues 1 to 562)
  AUTHORS   Cheng,Q.Y., Xiong,J., Ma,C.J., Dai,Y., Ding,J.H., Liu,F.L.,
            Yuan,B.F. and Feng,Y.Q.
  TITLE     Chemical tagging for sensitive determination of uridine
            modifications in RNA
  JOURNAL   Chem Sci 11 (7), 1878-1891 (2020)
   PUBMED   34123281
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 562)
  AUTHORS   Hicks,D.G., Janarthanan,B.R., Vardarajan,R., Kulkarni,S.A.,
            Khoury,T., Dim,D., Budd,G.T., Yoder,B.J., Tubbs,R., Schreeder,M.T.,
            Estopinal,N.C., Beck,R.A., Wang,Y., Ring,B.Z., Seitz,R.S. and
            Ross,D.T.
  TITLE     The expression of TRMT2A, a novel cell cycle regulated protein,
            identifies a subset of breast cancer patients with HER2
            over-expression that are at an increased risk of recurrence
  JOURNAL   BMC Cancer 10, 108 (2010)
   PUBMED   20307320
  REMARK    GeneRIF: TRMT2A staining showed a strong correlation with
            likelihood of recurrence at five years in 67 HER2+ breast cancer.
            Publication Status: Online-Only
REFERENCE   7  (residues 1 to 562)
  AUTHORS   Liu,Y.L., Fann,C.S., Liu,C.M., Chang,C.C., Yang,W.C., Wu,J.Y.,
            Hung,S.I., Chan,H.Y., Chen,J.J., Hsieh,M.H., Hwang,T.J.,
            Faraone,S.V., Tsuang,M.T., Chen,W.J. and Hwu,H.G.
  TITLE     HTF9C gene of 22q11.21 region associates with schizophrenia having
            deficit-sustained attention
  JOURNAL   Psychiatr Genet 17 (6), 333-338 (2007)
   PUBMED   18075473
  REMARK    GeneRIF: Single nucleotid polymorphisms of this gene may be
            associated with a deficit in sustained attention within
            schizophrenia, in a Taiwanese cohort.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (residues 1 to 562)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
REFERENCE   9  (residues 1 to 562)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
REFERENCE   10 (residues 1 to 562)
  AUTHORS   Di Matteo,G., Salerno,M., Guarguaglini,G., Di Fiore,B., Palitti,F.
            and Lavia,P.
  TITLE     Interactions with single-stranded and double-stranded DNA-binding
            factors and alternative promoter conformation upon transcriptional
            activation of the Htf9-a/RanBP1 and Htf9-c genes
  JOURNAL   J Biol Chem 273 (1), 495-505 (1998)
   PUBMED   9417108
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK057029.1, AC006547.9 and
            AI539558.1.
            
            Summary: The protein encoded by this gene is of unknown function.
            However, it is orthologous to the mouse Trmt2a gene and contains an
            RNA methyltransferase domain. Expression of this gene varies during
            the cell cycle, with aberrant expression being a possible biomarker
            in certain breast cancers. Several transcript variants encoding two
            different isoforms have been found for this gene. [provided by
            RefSeq, Apr 2012].
            
            Transcript Variant: This variant (3) uses an alternate splice
            junction at the 5' end of a coding exon compared to variant 1. The
            resulting isoform (b) has a shorter and distinct C-terminus
            compared to isoform a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK057029.1, SRR14038195.498584.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.21"
     Protein         1..562
                     /product="tRNA (uracil-5-)-methyltransferase homolog A
                     isoform b"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog A; tRNA
                     methyltransferase 2 homolog A; hpaII tiny fragments locus
                     9c protein; TRM2 tRNA methyltransferase 2 homolog A; mRNA
                     (uracil-5-)-methyltransferase TRMT2A"
                     /calculated_mol_wt=61848
     Region          1..37
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Region          68..146
                     /region_name="RRM_TRMT2A"
                     /note="RNA recognition motif (RRM) found in tRNA
                     (uracil-5-)-methyltransferase homolog A (TRMT2A) and
                     similar proteins; cd12439"
                     /db_xref="CDD:409873"
     Region          145..165
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Region          <178..540
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     Site            378
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q8IZ69.2)"
     CDS             1..562
                     /gene="TRMT2A"
                     /gene_synonym="HTF9C"
                     /coded_by="NM_001257994.2:321..2009"
                     /note="isoform b is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS58793.1"
                     /db_xref="GeneID:27037"
                     /db_xref="HGNC:HGNC:24974"
                     /db_xref="MIM:611151"
ORIGIN      
        1 msenldnegp kpmescgqes ssalscptvs vppaapaale evekegagaa tgpgpqpgly
       61 syirddlfts eifklelqnv prhasfsdvr rflgrfglqp hktklfgqpp cafvtfrsaa
      121 erdkalrvlh galwkgrpls vrlarpkadp marrrrqege seppvtrvad vvtplwtvpy
      181 aeqlerkqle ceqvlqklak eigstnrall pwlleqrhkh nkaccplegv rpspqqteyr
      241 nkceflvgvg vdgedntvgc rlgkykggtc avaapfdtvh ipeatkqvvk afqefirstp
      301 ysaydpetyt ghwkqltvrt srrhqamaia yfhpqklspe elaelktsla qhftagpgra
      361 sgvtclyfve egqrktpsqe glplehvagd rcihedllgl tfrisphaff qvntpaaevl
      421 ytviqdwaql dagsmvldvc cgtgtiglal arkvkrvigv elcpeaveda rvnaqdnels
      481 nvefhcgrae dlvptlvsrl asqhlvaild ppraglhskv ilairraknl rrllyvscnp
      541 raamgnfvda plfppqplqs pi
//
LOCUS       NP_001380339             443 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA:m(4)X modification enzyme TRM13 homolog isoform 3 [Homo
            sapiens].
ACCESSION   NP_001380339
VERSION     NP_001380339.1
DBSOURCE    REFSEQ: accession NM_001393410.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 443)
  AUTHORS   Li,H., Dong,H., Xu,B., Xiong,Q.P., Li,C.T., Yang,W.Q., Li,J.,
            Huang,Z.X., Zeng,Q.Y., Wang,E.D. and Liu,R.J.
  TITLE     A dual role of human tRNA methyltransferase hTrmt13 in regulating
            translation and transcription
  JOURNAL   EMBO J 41 (6), e108544 (2022)
   PUBMED   34850409
  REMARK    GeneRIF: A dual role of human tRNA methyltransferase hTrmt13 in
            regulating translation and transcription.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445928.8.
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p21.2"
     Protein         1..443
                     /product="tRNA:m(4)X modification enzyme TRM13 homolog
                     isoform 3"
                     /EC_number="2.1.1.225"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM13
                     homolog; tRNA [Gm4] methyltransferase; coiled-coil
                     domain-containing protein 76; tRNA methyltransferase 13
                     homolog; coiled-coil domain containing 76; tRNA:m(4)X
                     modification enzyme TRM13 homolog"
                     /calculated_mol_wt=49619
     Region          17..45
                     /region_name="zf-TRM13_CCCH"
                     /note="CCCH zinc finger in TRM13 protein; pfam11722"
                     /db_xref="CDD:463331"
     Region          127..431
                     /region_name="TRM13"
                     /note="Methyltransferase TRM13; pfam05206"
                     /db_xref="CDD:398743"
     CDS             1..443
                     /gene="TRMT13"
                     /gene_synonym="CCDC76; hTrmt13"
                     /coded_by="NM_001393410.1:7..1338"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="GeneID:54482"
                     /db_xref="HGNC:HGNC:25502"
ORIGIN      
        1 matsatspha pgfpaegrcg yyvekkkrfc rmvvaagkrf cgehagaaed fyiqdinagl
       61 rdeteipeql vpisslseeq leklikklrk aseglnstlk dhimshpalh dalndpkngd
      121 satkhlkqqa silgnienlk llgprrcfve fgagkgklsh wvdialkdae kvhfilvekv
      181 ttrfkvdgkh rkknsvferl qidiqhlcln kipvlreekl pvvgigkhlc gmatdlalrc
      241 lvetyaasfe erneeplakr ikndktekei ytlakegnek nvpekwnpva givialcchh
      301 rcdwrhyvgk eyfralglga vefhyfqrms swatcgmrkt sletsnsttk rqdnqnddse
      361 ehddggyrit ddgadclpgl lsveekkkig hlckllidqg riqylqqkgf spalqyytdp
      421 lvslenvllt alpnhssspe tta
//
LOCUS       NP_079193                504 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog B isoform a [Homo
            sapiens].
ACCESSION   NP_079193
VERSION     NP_079193.2
DBSOURCE    REFSEQ: accession NM_024917.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 504)
  AUTHORS   Liu,Y., He,X., Yuan,Y., Li,B., Liu,Z., Li,W., Li,K., Tan,S.,
            Zhu,Q., Tang,Z., Han,F., Wu,Z., Shen,L., Jiang,H., Tang,B., Qiu,J.,
            Hu,Z. and Wang,J.
  TITLE     Association of TRMT2B gene variants with juvenile amyotrophic
            lateral sclerosis
  JOURNAL   Front Med 18 (1), 68-80 (2024)
   PUBMED   37874476
  REMARK    GeneRIF: Association of TRMT2B gene variants with juvenile
            amyotrophic lateral sclerosis.
REFERENCE   2  (residues 1 to 504)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   3  (residues 1 to 504)
  AUTHORS   Dai,W., Li,A., Yu,N.J., Nguyen,T., Leach,R.W., Wuhr,M. and
            Kleiner,R.E.
  TITLE     Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated
            dihydrouridylation
  JOURNAL   Nat Chem Biol 17 (11), 1178-1187 (2021)
   PUBMED   34556860
REFERENCE   4  (residues 1 to 504)
  AUTHORS   Powell,C.A. and Minczuk,M.
  TITLE     TRMT2B is responsible for both tRNA and rRNA m5U-methylation in
            human mitochondria
  JOURNAL   RNA Biol 17 (4), 451-462 (2020)
   PUBMED   31948311
  REMARK    GeneRIF: TRMT2B is responsible for both tRNA and rRNA
            m(5)U-methylation in human mitochondria.
REFERENCE   5  (residues 1 to 504)
  AUTHORS   Carter,J.M., Emmett,W., Mozos,I.R., Kotter,A., Helm,M., Ule,J. and
            Hussain,S.
  TITLE     FICC-Seq: a method for enzyme-specified profiling of
            methyl-5-uridine in cellular RNA
  JOURNAL   Nucleic Acids Res 47 (19), e113 (2019)
   PUBMED   31361898
REFERENCE   6  (residues 1 to 504)
  AUTHORS   Lee,S.Y., Kang,M.G., Park,J.S., Lee,G., Ting,A.Y. and Rhee,H.W.
  TITLE     APEX Fingerprinting Reveals the Subcellular Localization of
            Proteins of Interest
  JOURNAL   Cell Rep 15 (8), 1837-1847 (2016)
   PUBMED   27184847
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA454040.1, BC034272.2 and
            Z97985.16.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Apr 15, 2002 this sequence version replaced NP_079193.1.
            
            Summary: This gene encodes a homolog of the TRM2 gene in S.
            cerevisiae. The yeast gene encodes a tRNA methyltransferase that
            plays a role in tRNA maturation. The yeast protein also has
            endo-exonuclease activity and may be involved in DNA double strand
            break repair. Alternative splicing results in multiple transcripts
            encoding different isoforms. [provided by RefSeq, Nov 2009].
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2, and 4 all encode isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC034272.2, SRR14038197.200797.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000372936.4/ ENSP00000362027.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.1"
     Protein         1..504
                     /product="tRNA (uracil-5-)-methyltransferase homolog B
                     isoform a"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog; TRM2
                     homolog; tRNA (uracil(54)-C(5))-methyltransferase homolog;
                     TRM2 tRNA methyltransferase 2 homolog B; TRM2 homolog B;
                     rRNA (uracil-5-)-methyltransferase TRMT2B; tRNA
                     (uracil-5-)-methyltransferase homolog B"
                     /calculated_mol_wt=56345
     Region          <94..503
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     CDS             1..504
                     /gene="TRMT2B"
                     /gene_synonym="CXorf34; dJ341D10.3"
                     /coded_by="NM_024917.6:802..2316"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS14477.1"
                     /db_xref="GeneID:79979"
                     /db_xref="HGNC:HGNC:25748"
                     /db_xref="MIM:301128"
ORIGIN      
        1 maglkrrvpl hslryfismv glfskpgllp wyarnppgws qlflgtvckg dftrviatkc
       61 qkgqksqkkp shlgpldgsw qerladvvtp lwrlsyeeql kvkfaaqkki lqrlesyiqm
      121 lngvsvttav pkserlscll hpiipspvin gyrnkstfsv nrgpdgnpkt vgfylgtwrd
      181 gnvvcvqsnh lknipekhsq vaqyyevflr qsplepclvf heggywrelt vrtnsqghtm
      241 aiitfhpqkl sqeelhvqke ivkeffirgp gaacgltsly fqestmtrcs hqqspyqllf
      301 gepyifeell slkirispda ffqintagae mlyrtvgelt gvnsdtilld iccgtgvigl
      361 slaqhtsrvl gielleqave darwtaafng itnsefhtgq aekilpgllk skedgqsiva
      421 vvnparaglh ykviqairnf raihtlvfvs cklhgestrn vielccppdp akkllgepfv
      481 lqqavpvdlf phtphcelvl lftr
//
LOCUS       NP_001266387             521 aa            linear   VRT 18-JUN-2025
DEFINITION  cytochrome P450 17A2 [Oreochromis niloticus].
ACCESSION   NP_001266387 XP_003454718
VERSION     NP_001266387.1
DBSOURCE    REFSEQ: accession NM_001279458.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 521)
  AUTHORS   Zhou,L.Y., Wang,D.S., Kobayashi,T., Yano,A., Paul-Prasanth,B.,
            Suzuki,A., Sakai,F. and Nagahama,Y.
  TITLE     A novel type of P450c17 lacking the lyase activity is responsible
            for C21-steroid biosynthesis in the fish ovary and head kidney
  JOURNAL   Endocrinology 148 (9), 4282-4291 (2007)
   PUBMED   17569754
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EF423917.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003454718.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF423917.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767853, SAMN00767858
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG3"
                     /linkage_group="LG3"
     Protein         1..521
                     /product="cytochrome P450 17A2"
                     /note="cytochrome P450 family 17 polypeptide 2"
                     /calculated_mol_wt=57505
     Region          80..508
                     /region_name="cytochrome_P450"
                     /note="cytochrome P450 (CYP) superfamily; cl41757"
                     /db_xref="CDD:477761"
     Site            order(141,145,152,199,317..318,321..322,325..326,329,380,
                     390,392,415,451..453,457..461,464..465)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:410651"
     Site            order(225..226,317,320..321,325,388..391)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:410651"
     CDS             1..521
                     /gene="cyp17a2"
                     /coded_by="NM_001279458.1:87..1652"
                     /db_xref="GeneID:100702216"
ORIGIN      
        1 mltcllsflp pslspsvlit lftvvvvvlf lttcqlvpet epsargsipc lprlpflgsl
       61 pwlggglpph llftqmshry gplfglylgp hytvvinshq harevlmqkg kdfagrpsmv
      121 ttnlltrggk diafsdytpl wkyhrrlvhn sftlfgegtt rlqdivlsev dslcvellss
      181 ekqgfdpssa vtravtniic tlvfsatyrh gdaelqeviq ynngivetia rgglvdiypw
      241 lkvfpnksls klkkcitird qlltrklqeh klsrsdgdpc dlldallkgq tsgqgqksse
      301 skddgitddh vlmtaxeafg agvettsttl lwilayllhh pevqervqke ldehvgsert
      361 vtisyrgqlp ylnsvinegm rirpvspvli phtamtnssi gghavsqgtr vlvnmwsihh
      421 dphhwdkpdl fnperfldhh gqqvtpssfl pfgagprvcv gkslarlelf lflssllqrm
      481 sfrvprgapl pnlqgrlgvv lqpspfkvvv ipragwedgg k
//
LOCUS       NP_001337522             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337522
VERSION     NP_001337522.1
DBSOURCE    REFSEQ: accession NM_001350593.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (15), as well as variants 8-14 and
            16-19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.67559.1,
                                           SRR18074968.1190132.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2158188, SAMN04284274
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350593.2:1654..2346"
                     /note="isoform e is encoded by transcript variant 15"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001337516             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337516
VERSION     NP_001337516.1
DBSOURCE    REFSEQ: accession NM_001350587.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (9), as well as variants 8 and
            10-19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038196.2013426.1,
                                           SRR18074968.2025528.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA2144335
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350587.2:1300..1992"
                     /note="isoform e is encoded by transcript variant 9"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001266489             486 aa            linear   VRT 18-JUN-2025
DEFINITION  steroidogenic factor 1a [Oreochromis niloticus].
ACCESSION   NP_001266489 XP_003455075
VERSION     NP_001266489.2
DBSOURCE    REFSEQ: accession NM_001279560.2
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 486)
  AUTHORS   Cao,J., Chen,J., Jiang,Z., Luo,Y. and Gan,X.
  TITLE     Molecular cloning and expression analysis of FTZ-F1 in the GIFT
            tilapia, Oreochromis niloticus
  JOURNAL   Dongwuxue Yanjiu 33 (E3-4), E40-E46 (2012)
   PUBMED   22855453
REFERENCE   2  (residues 1 to 486)
  AUTHORS   Yoshiura,Y., Senthilkumaran,B., Watanabe,M., Oba,Y., Kobayashi,T.
            and Nagahama,Y.
  TITLE     Synergistic expression of Ad4BP/SF-1 and cytochrome P-450 aromatase
            (ovarian type) in the ovary of Nile tilapia, Oreochromis niloticus,
            during vitellogenesis suggests transcriptional interaction
  JOURNAL   Biol Reprod 68 (5), 1545-1553 (2003)
   PUBMED   12606465
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            MKQE02000012.1.
            
            On Mar 9, 2017 this sequence version replaced NP_001266489.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: JF742993.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN07160562 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG12"
                     /linkage_group="LG12"
     Protein         1..486
                     /product="steroidogenic factor 1a"
                     /note="fushi tarazu factor-1; steroidogenic factor-1;
                     nuclear receptor subfamily 5 group A member 1"
                     /calculated_mol_wt=54884
     Region          26..118
                     /region_name="NR_DBD_Lrh-1_like"
                     /note="The DNA-binding domain of Lrh-1 like nuclear
                     receptor family like is composed of two C4-type zinc
                     fingers; cd07167"
                     /db_xref="CDD:143541"
     Site            order(26,29,43,46,62,68,78,81)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:143541"
     Site            order(36..38,44..45,47,49,51..52,55,75..76,82,95..97,
                     100..106,112)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143541"
     Region          253..482
                     /region_name="NR_LBD_Ftz-F1_like"
                     /note="The ligand binding domain of FTZ-F1 like nuclear
                     receptors; cd06944"
                     /db_xref="CDD:132742"
     Site            order(285,288..289,325..326,329,333,348,370..371,456,
                     459..460,463)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:132742"
     Site            order(297,300,304,314,317..318,321..322,473..474,477..478)
                     /site_type="other"
                     /note="coactivator recognition site [polypeptide binding]"
                     /db_xref="CDD:132742"
     CDS             1..486
                     /gene="nr5a1a"
                     /gene_synonym="ftz-f1; nr5a1; SF-1; SF-1/Ad4BP"
                     /coded_by="NM_001279560.2:223..1683"
                     /db_xref="GeneID:100628563"
ORIGIN      
        1 mlgdkahgvt lkvmeytyde dleelcpvcg dkvsgyhygl ltcesckgff krtvqnnkry
       61 tcaenqecki dktqrkrcpf crfqkclnvg mrleavradr mrggrnkfgp mykrdralkq
      121 qkkalirsng fklestappp asplqadygf tgtlhtlpti sksllpstps sitptdyean
      181 lygppslgma mqshvplttq yqytafpgra ikaecpdyts spetltgypy pdmypsaspq
      241 ppslpplvle llrcdpdelv vqnkivthlq qeqngrgrle kpstfslmcr madqtlfsiv
      301 ewarsciffk elrvgdqmkl lhncwsellv ldhifrqvqh akedsillvt gqevelssil
      361 sqaegtlssl vqrgqelaar lrvlqvdrre iaclkflllf npnvkllenq afvegvqeqv
      421 naalleytls aypqfqekfs qllvrlpelr slstqaedyl cymhvsgevp cnnlliemlh
      481 akracv
//
LOCUS       NP_001337515             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337515
VERSION     NP_001337515.1
DBSOURCE    REFSEQ: accession NM_001350586.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (8), as well as variants 9-19,
            encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074969.956360.1,
                                           SRR14038192.3683007.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350586.2:1039..1731"
                     /note="isoform e is encoded by transcript variant 8"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001336416             157 aa            linear   PRI 18-JUN-2025
DEFINITION  E3 SUMO-protein ligase NSE2 isoform 2 [Homo sapiens].
ACCESSION   NP_001336416
VERSION     NP_001336416.1
DBSOURCE    REFSEQ: accession NM_001349487.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 157)
  AUTHORS   Di Benedetto,C., Oh,J., Choudhery,Z., Shi,W., Valdes,G. and
            Betancur,P.
  TITLE     NSMCE2, a novel super-enhancer-regulated gene, is linked to poor
            prognosis and therapy resistance in breast cancer
  JOURNAL   BMC Cancer 22 (1), 1056 (2022)
   PUBMED   36224576
  REMARK    GeneRIF: NSMCE2, a novel super-enhancer-regulated gene, is linked
            to poor prognosis and therapy resistance in breast cancer.
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 157)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (residues 1 to 157)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (residues 1 to 157)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   5  (residues 1 to 157)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 157)
  AUTHORS   Potts,P.R.
  TITLE     The Yin and Yang of the MMS21-SMC5/6 SUMO ligase complex in
            homologous recombination
  JOURNAL   DNA Repair (Amst) 8 (4), 499-506 (2009)
   PUBMED   19217832
  REMARK    Review article
REFERENCE   7  (residues 1 to 157)
  AUTHORS   Taylor,E.M., Copsey,A.C., Hudson,J.J., Vidot,S. and Lehmann,A.R.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   8  (residues 1 to 157)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   9  (residues 1 to 157)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   10 (residues 1 to 157)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     Human MMS21/NSE2 is a SUMO ligase required for DNA repair
  JOURNAL   Mol Cell Biol 25 (16), 7021-7032 (2005)
   PUBMED   16055714
  REMARK    GeneRIF: the human SMC5/6 complex and the SUMO ligase activity of
            hMMS21 are required for the prevention of DNA damage-induced
            apoptosis by facilitating DNA repair in human cells
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC126366.2 and BM993808.1.
            
            Summary: This gene encodes a member of a family of E3 small
            ubiquitin-related modifier (SUMO) ligases that mediates the
            attachment of a SUMO protein to proteins involved in nuclear
            transport, transcription, chromosome segregation and DNA repair.
            The encoded protein is part of the structural maintenance of
            chromosomes (SMC) 5/6 complex which plays a key role genome
            maintenance, facilitating chromosome segregation and suppressing
            mitotic recombination. A knockout of the orthologous mouse gene is
            lethal prior to embryonic day 10.5. Naturally occurring mutations
            in this gene, that abolish the SUMO ligase activity, are associated
            with primordial dwarfism and extreme insulin resistance. [provided
            by RefSeq, Mar 2017].
            
            Transcript Variant: This variant (4) lacks several exons and its 3'
            terminal exon extends past a splice site that is used in variant 1.
            This results in a novel 3' coding region and 3' UTR, compared to
            variant 1. It encodes isoform 2 which is shorter and has a distinct
            C-terminus, compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AL527284.3, AL548990.3 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..157
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.13"
     Protein         1..157
                     /product="E3 SUMO-protein ligase NSE2 isoform 2"
                     /note="E3 SUMO-protein ligase NSE2; methyl
                     methanesulfonate sensitivity gene 21; NSE2 (MMS21)
                     homolog, SMC5-SMC6 complex SUMO ligase; non-structural
                     maintenance of chromosomes element 2 homolog; zinc finger,
                     MIZ-type containing 7; non-SMC element 2, MMS21 homolog;
                     NSMCE2/PVT1 fusion; PVT1/NSMCE2 fusion; E3 SUMO-protein
                     transferase NSE2"
                     /calculated_mol_wt=17466
     Site            1
                     /site_type="acetylation"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0007744|PubMed:20068231; propagated from
                     UniProtKB/Swiss-Prot (Q96MF7.2)"
     Site            116
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q96MF7.2)"
     CDS             1..157
                     /gene="NSMCE2"
                     /gene_synonym="C8orf36; MMS21; NSE2; ZMIZ7"
                     /coded_by="NM_001349487.2:210..683"
                     /note="isoform 2 is encoded by transcript variant 4"
                     /db_xref="CCDS:CCDS87625.1"
                     /db_xref="GeneID:286053"
                     /db_xref="HGNC:HGNC:26513"
                     /db_xref="MIM:617246"
ORIGIN      
        1 mpgrsssnsg stgfisfsgv esalsslknf qacinsgmdt assvaldlve sqtevsseys
       61 mdkamvefat ldrqlnhyvk avqstinhvk eerpekipdl kllvekkfla lqsknsdadf
      121 qnnekfvqfk qqlkelkkqc kstcfalvrl feirelt
//
LOCUS       NP_001297020             215 aa            linear   VRT 18-JUN-2025
DEFINITION  suppressor of cytokine signaling 1a [Oreochromis niloticus].
ACCESSION   NP_001297020
VERSION     NP_001297020.1
DBSOURCE    REFSEQ: accession NM_001310091.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 215)
  AUTHORS   Liu,C.Z., He,A.Y., Chen,L.Q., Limbu,S.M., Wang,Y.W., Zhang,M.L. and
            Du,Z.Y.
  TITLE     Molecular characterization and immune response to
            lipopolysaccharide (LPS) of the suppressor of cytokine signaling
            (SOCS)-1, 2 and 3 genes in Nile tilapia (Oreochromis niloticus)
  JOURNAL   Fish Shellfish Immunol 50, 160-167 (2016)
   PUBMED   26820103
  REMARK    GeneRIF: NtSOCS-1 and 3 were highly expressed in immune-related
            tissues, such as gills, foregut and head kidney. However, NtSOCS-2
            was superlatively expressed in liver, brain and heart.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KR149237.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: KR149237.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..215
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG4"
                     /linkage_group="LG4"
     Protein         1..215
                     /product="suppressor of cytokine signaling 1a"
                     /calculated_mol_wt=24315
     Region          72..169
                     /region_name="SH2_SOCS1"
                     /note="Src homology 2 (SH2) domain found in suppressor of
                     cytokine signaling (SOCS) proteins; cd10382"
                     /db_xref="CDD:198245"
     Site            order(90,108,110,118,131)
                     /site_type="other"
                     /note="phosphotyrosine binding pocket [polypeptide
                     binding]"
                     /db_xref="CDD:198245"
     Site            order(141,143,158)
                     /site_type="other"
                     /note="hydrophobic binding pocket [polypeptide binding]"
                     /db_xref="CDD:198245"
     Region          175..211
                     /region_name="SOCS"
                     /note="SOCS (suppressors of cytokine signaling) box. The
                     SOCS box is found in the C-terminal region of CIS/SOCS
                     family proteins (in combination with a SH2 domain), ASBs
                     (ankyrin repeat-containing proteins with a SOCS box), SSBs
                     (SPRY domain-containing proteins...; cl02533"
                     /db_xref="CDD:470605"
     CDS             1..215
                     /gene="socs1a"
                     /gene_synonym="socs1"
                     /coded_by="NM_001310091.1:1..648"
                     /db_xref="GeneID:100706055"
ORIGIN      
        1 mvadgtvegh dktrlsslss ssssslssss sstlrteveq lqrqanqhrr tpsvylthfp
       61 tftckedcri itdtaskler cgfywgplgv edahrmlrda plgsflirds rqkdvfftls
      121 yhaktgpvsv ridykhqkfs lagnersfqt lfallehyin spkkslsvpy rkweptlqel
      181 crkrilelcg gasqvpelpl thvaqdflle fpykl
//
LOCUS       NP_001072994             500 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein Helios isoform 2 [Homo sapiens].
ACCESSION   NP_001072994 XP_005246444
VERSION     NP_001072994.1
DBSOURCE    REFSEQ: accession NM_001079526.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 500)
  AUTHORS   Velde,H.M., Vaseghi-Shanjani,M., Smits,J.J., Ramakrishnan,G.,
            Oostrik,J., Wesdorp,M., Astuti,G., Yntema,H.G., Hoefsloot,L.,
            Lanting,C.P., Huynen,M.A., Lehman,A., Turvey,S.E., Pennings,R.J.E.
            and Kremer,H.
  CONSRTM   DOOFNL Consortium
  TITLE     Exome variant prioritization in a large cohort of hearing-impaired
            individuals indicates IKZF2 to be associated with non-syndromic
            hearing loss and guides future research of unsolved cases
  JOURNAL   Hum Genet 143 (11), 1379-1399 (2024)
   PUBMED   39406892
REFERENCE   2  (residues 1 to 500)
  AUTHORS   Lukasik,M., Telec,M., Kazmierski,R., Wojtasz,I.,
            Andrzejewska-Gorczynska,N., Kociemba,W., Dworacki,G., Kozubski,W.P.
            and Frydrychowicz,M.
  TITLE     Temporal changes in regulatory T cell subsets defined by the
            transcription factor Helios in stroke and their potential role in
            stroke-associated infection: a prospective case-control study
  JOURNAL   J Neuroinflammation 20 (1), 275 (2023)
   PUBMED   37996909
  REMARK    GeneRIF: Temporal changes in regulatory T cell subsets defined by
            the transcription factor Helios in stroke and their potential role
            in stroke-associated infection: a prospective case-control study.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 500)
  AUTHORS   Mohajeri,A., Vaseghi-Shanjani,M., Rosenfeld,J.A., Yang,G.X., Lu,H.,
            Sharma,M., Lin,S., Salman,A., Waqas,M., Sababi Azamian,M.,
            Worley,K.C., Del Bel,K.L., Kozak,F.K., Rahmanian,R., Biggs,C.M.,
            Hildebrand,K.J., Lalani,S.R., Nicholas,S.K., Scott,D.A.,
            Mostafavi,S., van Karnebeek,C., Henkelman,E., Halparin,J.,
            Yang,C.L., Armstrong,L., Turvey,S.E. and Lehman,A.
  CONSRTM   Undiagnosed Diseases Network; Care4Rare Canada Consortium
  TITLE     Dominant negative variants in IKZF2 cause ICHAD syndrome, a new
            disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay
  JOURNAL   J Med Genet 60 (11), 1092-1104 (2023)
   PUBMED   37316189
  REMARK    GeneRIF: Dominant negative variants in IKZF2 cause ICHAD syndrome,
            a new disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay.
REFERENCE   4  (residues 1 to 500)
  AUTHORS   Tarighi,M., Shahbazi,M., Saadat,P., Daraei,A., Alizadeh Khatir,A.,
            Rahimifard,K. and Mohammadnia-Afrouzi,M.
  TITLE     Decreased frequency of regulatory T cells and level of helios gene
            expression in secondary progressive multiple sclerosis patients:
            Evidence about the development of multiple sclerosis
  JOURNAL   Int Immunopharmacol 116, 109797 (2023)
   PUBMED   36738680
  REMARK    GeneRIF: Decreased frequency of regulatory T cells and level of
            helios gene expression in secondary progressive multiple sclerosis
            patients: Evidence about the development of multiple sclerosis.
REFERENCE   5  (residues 1 to 500)
  AUTHORS   Zhang,H., Jadhav,R.R., Cao,W., Goronzy,I.N., Zhao,T.V., Jin,J.,
            Ohtsuki,S., Hu,Z., Morales,J., Greenleaf,W.J., Weyand,C.M. and
            Goronzy,J.J.
  TITLE     Aging-associated HELIOS deficiency in naive CD4+ T cells alters
            chromatin remodeling and promotes effector cell responses
  JOURNAL   Nat Immunol 24 (1), 96-109 (2023)
   PUBMED   36510022
  REMARK    GeneRIF: Aging-associated HELIOS deficiency in naive CD4[+] T cells
            alters chromatin remodeling and promotes effector cell responses.
REFERENCE   6  (residues 1 to 500)
  AUTHORS   Nakase,K., Ishimaru,F., Fujii,K., Tabayashi,T., Kozuka,T.,
            Sezaki,N., Matsuo,Y. and Harada,M.
  TITLE     Overexpression of novel short isoforms of Helios in a patient with
            T-cell acute lymphoblastic leukemia
  JOURNAL   Exp Hematol 30 (4), 313-317 (2002)
   PUBMED   11937265
  REMARK    GeneRIF: Novel short isoforms of Helios are overexpressed in a
            patient with T-cell acute lymphoblastic leukemia and may contribute
            to the development of T-cell malignancies. Data for unaltered
            Helios indicates tumor suppressor function.
REFERENCE   7  (residues 1 to 500)
  AUTHORS   Perdomo,J., Holmes,M., Chong,B. and Crossley,M.
  TITLE     Eos and pegasus, two members of the Ikaros family of proteins with
            distinct DNA binding activities
  JOURNAL   J Biol Chem 275 (49), 38347-38354 (2000)
   PUBMED   10978333
REFERENCE   8  (residues 1 to 500)
  AUTHORS   Hosokawa,Y., Maeda,Y. and Seto,M.
  TITLE     Human Helios, an Ikaros-related zinc finger DNA binding protein:
            cDNA cloning and tissue expression pattern
  JOURNAL   Immunogenetics 50 (1-2), 106-108 (1999)
   PUBMED   10541817
REFERENCE   9  (residues 1 to 500)
  AUTHORS   Kelley,C.M., Ikeda,T., Koipally,J., Avitahl,N., Wu,L.,
            Georgopoulos,K. and Morgan,B.A.
  TITLE     Helios, a novel dimerization partner of Ikaros expressed in the
            earliest hematopoietic progenitors
  JOURNAL   Curr Biol 8 (9), 508-515 (1998)
   PUBMED   9560339
REFERENCE   10 (residues 1 to 500)
  AUTHORS   Hahm,K., Cobb,B.S., McCarty,A.S., Brown,K.E., Klug,C.A., Lee,R.,
            Akashi,K., Weissman,I.L., Fisher,A.G. and Smale,S.T.
  TITLE     Helios, a T cell-restricted Ikaros family member that
            quantitatively associates with Ikaros at centromeric
            heterochromatin
  JOURNAL   Genes Dev 12 (6), 782-796 (1998)
   PUBMED   9512513
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC079610.4, BC028936.1,
            AC108066.3 and AI458439.1.
            
            On Aug 31, 2013 this sequence version replaced XP_005246444.1.
            
            Summary: This gene encodes a member of the Ikaros family of
            zinc-finger proteins. Three members of this protein family (Ikaros,
            Aiolos and Helios) are hematopoietic-specific transcription factors
            involved in the regulation of lymphocyte development. This protein
            forms homo- or hetero-dimers with other Ikaros family members, and
            is thought to function predominantly in early hematopoietic
            development. Multiple transcript variants encoding different
            isoforms have been found for this gene, but the biological validity
            of some variants has not been determined. [provided by RefSeq, Jul
            2008].
            
            Transcript Variant: This variant (2) differs in the 5' UTR and uses
            an alternate in-frame splice site in the coding region, compared to
            variant 1. The resulting protein (isoform 2) is shorter than
            isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC028936.1, SRR18074969.612271.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..500
                     /product="zinc finger protein Helios isoform 2"
                     /note="zinc finger protein, subfamily 1A, 2 (Helios); zinc
                     finger DNA binding protein Helios; zinc finger protein
                     Helios; ikaros family zinc finger protein 2"
                     /calculated_mol_wt=56635
     Region          107..>181
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          116..136
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(121,123,125,127..128,131..132,135,149,151,155..156,
                     159..160,163,177,179,181,183..184,187..188,192)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          128..153
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          144..164
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          172..193
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..500
                     /gene="IKZF2"
                     /gene_synonym="ANF1A2; HELIOS; ICHAD; IMDIA; ZNF1A2;
                     ZNFN1A2"
                     /coded_by="NM_001079526.2:320..1822"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="CCDS:CCDS46507.1"
                     /db_xref="GeneID:22807"
                     /db_xref="HGNC:HGNC:13177"
                     /db_xref="MIM:606234"
ORIGIN      
        1 meteaidgyi tcdnelsper ehsnmaidlt sstpngqhas pshmtstnsv klemqsdeec
       61 drkplsrede irghdegssl eepliessev adnrkvqelq geggirlpng erpfhcnqcg
      121 asftqkgnll rhiklhsgek pfkcpfcsya crrrdaltgh lrthsvgkph kcnycgrsyk
      181 qrssleehke rchnylqnvs meaagqvmsh hvppmedcke qepimdnnis lvpferpavi
      241 ekltgnmgkr ksstpqkfvg eklmrfsypd ihfdmnltye keaelmqshm mdqainnait
      301 ylgaealhpl mqhppstiae vapvissays qvyhpnrier pisretadsh ennmdgpisl
      361 irpksrpqer easpsnscld stdsesshdd hqsyqghpal npkrkqspay mkedvkaldt
      421 tkapkgslkd iykvfngege qirafkcehc rvlfldhvmy tihmgchgyr dplecnicgy
      481 rsqdryefss hivrgehtfh
//
LOCUS       NP_001269823             282 aa            linear   VRT 18-JUN-2025
DEFINITION  caspase-3a [Oreochromis niloticus].
ACCESSION   NP_001269823 XP_003449739
VERSION     NP_001269823.1
DBSOURCE    REFSEQ: accession NM_001282894.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 282)
  AUTHORS   Monteiro,S.M., dos Santos,N.M., Calejo,M., Fontainhas-Fernandes,A.
            and Sousa,M.
  TITLE     Copper toxicity in gills of the teleost fish, Oreochromis
            niloticus: effects in apoptosis induction and cell proliferation
  JOURNAL   Aquat Toxicol 94 (3), 219-228 (2009)
   PUBMED   19656581
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from GQ421464.1.
            
            On Sep 20, 2013 this sequence version replaced XP_003449739.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GQ421464.1, FF279597.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG6"
                     /linkage_group="LG6"
     Protein         1..282
                     /product="caspase-3a"
                     /EC_number="3.4.22.56"
                     /note="caspase-3"
                     /calculated_mol_wt=30899
     Region          45..280
                     /region_name="CASc"
                     /note="Caspase, interleukin-1 beta converting enzyme (ICE)
                     homologues; Cysteine-dependent aspartate-directed
                     proteases that mediate programmed cell death (apoptosis).
                     Caspases are synthesized as inactive zymogens and
                     activated by proteolysis of the peptide...; cd00032"
                     /db_xref="CDD:237997"
     Site            order(73,131,170,177,209..214,218..219)
                     /site_type="other"
                     /note="substrate pocket [chemical binding]"
                     /db_xref="CDD:237997"
     Site            order(130,172)
                     /site_type="active"
                     /db_xref="CDD:237997"
     Site            order(178,194..195,202,205,208,231,239,245,265,270..271,
                     273,276..277)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:237997"
     Site            order(179,193)
                     /site_type="active"
                     /note="proteolytic cleavage site [active]"
                     /db_xref="CDD:237997"
     CDS             1..282
                     /gene="casp3a"
                     /coded_by="NM_001282894.1:80..928"
                     /db_xref="GeneID:100534438"
ORIGIN      
        1 msengsgpgv ddtdakpgng krsagsssas vpmdvdakpq shsfryrldf psigqciiin
       61 nknfdrstgm nqrngtdvda gnamrvfknl gynvkmyndq tvdqmmnvlt daskedhsns
      121 asfvcillsh gdegvffgtd gsvalkhlts lfrgdrcksl vgkpqlffiq acrgtdldpg
      181 ietdsetdgv kipveanfly afspapgyys wrntmtgswf iqsvcdmisk ygkeleilhi
      241 mtrvnhkvav efesasnspg fdakkqipci vsmltkemyf sr
//
LOCUS       NP_001269824             512 aa            linear   VRT 18-JUN-2025
DEFINITION  cytochrome P450 26B1 [Oreochromis niloticus].
ACCESSION   NP_001269824 XP_003457386
VERSION     NP_001269824.1
DBSOURCE    REFSEQ: accession NM_001282895.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KC119084.1.
            
            On Sep 20, 2013 this sequence version replaced XP_003457386.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KC119084.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2482242, SAMEA2482244
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG3"
                     /linkage_group="LG3"
     Protein         1..512
                     /product="cytochrome P450 26B1"
                     /calculated_mol_wt=57657
     Region          60..490
                     /region_name="cytochrome_P450"
                     /note="cytochrome P450 (CYP) superfamily; cl41757"
                     /db_xref="CDD:477761"
     Site            order(138,142,149,193,292..293,296..297,300..301,304,362,
                     371,373,396,433..435,439..443,446..447)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:410651"
     Site            order(217..218,292,295..296,300,369..372)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:410651"
     CDS             1..512
                     /gene="cyp26b1"
                     /coded_by="NM_001282895.1:1..1539"
                     /db_xref="GeneID:100690880"
ORIGIN      
        1 mlfdsfdlvs alatlaaclv smalllavsq qlwqlrwtat rdkncklpmp kgsmgfpfig
       61 etchwllqgs sfhasrrqky gnvfkthllg rpvirvtgae nvrkvlmgeh tlvavdwpqs
      121 tstllgpnsl ansigdihrk rrkvfakvfs healesylpk iqqviqeslr vwsstpepin
      181 vyresqrlsf tmavrvllgf rvteeemkhl fstfqdfvnn lfslpidlpf sgyrrgirar
      241 dtlqksieka irekplctqg kdysdaldvl mesakengse ltmqelkest ielifaafat
      301 tasastslim qllrhpqvle rlreelrsrg llhngclcpe aelrlgtiis lkyldcvike
      361 vlrlftpvsg ayrtamqtfe ldgvqipkgw svmysirdth dtaavfkdvd afdpdrfsqe
      421 rsedkegrfh ylpfgggvrs clgkqlatlf lrilaielac tsrfelatrn fprvitvpvv
      481 hpvdglkvkf ygldsnqnei makseellga tv
//
LOCUS       NP_892029                625 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog A isoform a [Homo
            sapiens].
ACCESSION   NP_892029
VERSION     NP_892029.2
DBSOURCE    REFSEQ: accession NM_182984.5
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 625)
  AUTHORS   Witzenberger,M., Burczyk,S., Settele,D., Mayer,W., Welp,L.M.,
            Heiss,M., Wagner,M., Monecke,T., Janowski,R., Carell,T., Urlaub,H.,
            Hauck,S.M., Voigt,A. and Niessing,D.
  TITLE     Human TRMT2A methylates tRNA and contributes to translation
            fidelity
  JOURNAL   Nucleic Acids Res 51 (16), 8691-8710 (2023)
   PUBMED   37395448
  REMARK    GeneRIF: Human TRMT2A methylates tRNA and contributes to
            translation fidelity.
REFERENCE   2  (residues 1 to 625)
  AUTHORS   Dai,W., Li,A., Yu,N.J., Nguyen,T., Leach,R.W., Wuhr,M. and
            Kleiner,R.E.
  TITLE     Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated
            dihydrouridylation
  JOURNAL   Nat Chem Biol 17 (11), 1178-1187 (2021)
   PUBMED   34556860
REFERENCE   3  (residues 1 to 625)
  AUTHORS   Pereira,M., Ribeiro,D.R., Pinheiro,M.M., Ferreira,M., Kellner,S.
            and Soares,A.R.
  TITLE     m5U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation
            of tRNA-Derived Small RNAs
  JOURNAL   Int J Mol Sci 22 (6), 2941 (2021)
   PUBMED   33799331
  REMARK    GeneRIF: m(5)U54 tRNA Hypomodification by Lack of TRMT2A Drives the
            Generation of tRNA-Derived Small RNAs.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 625)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (residues 1 to 625)
  AUTHORS   Cheng,Q.Y., Xiong,J., Ma,C.J., Dai,Y., Ding,J.H., Liu,F.L.,
            Yuan,B.F. and Feng,Y.Q.
  TITLE     Chemical tagging for sensitive determination of uridine
            modifications in RNA
  JOURNAL   Chem Sci 11 (7), 1878-1891 (2020)
   PUBMED   34123281
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 625)
  AUTHORS   Hicks,D.G., Janarthanan,B.R., Vardarajan,R., Kulkarni,S.A.,
            Khoury,T., Dim,D., Budd,G.T., Yoder,B.J., Tubbs,R., Schreeder,M.T.,
            Estopinal,N.C., Beck,R.A., Wang,Y., Ring,B.Z., Seitz,R.S. and
            Ross,D.T.
  TITLE     The expression of TRMT2A, a novel cell cycle regulated protein,
            identifies a subset of breast cancer patients with HER2
            over-expression that are at an increased risk of recurrence
  JOURNAL   BMC Cancer 10, 108 (2010)
   PUBMED   20307320
  REMARK    GeneRIF: TRMT2A staining showed a strong correlation with
            likelihood of recurrence at five years in 67 HER2+ breast cancer.
            Publication Status: Online-Only
REFERENCE   7  (residues 1 to 625)
  AUTHORS   Liu,Y.L., Fann,C.S., Liu,C.M., Chang,C.C., Yang,W.C., Wu,J.Y.,
            Hung,S.I., Chan,H.Y., Chen,J.J., Hsieh,M.H., Hwang,T.J.,
            Faraone,S.V., Tsuang,M.T., Chen,W.J. and Hwu,H.G.
  TITLE     HTF9C gene of 22q11.21 region associates with schizophrenia having
            deficit-sustained attention
  JOURNAL   Psychiatr Genet 17 (6), 333-338 (2007)
   PUBMED   18075473
  REMARK    GeneRIF: Single nucleotid polymorphisms of this gene may be
            associated with a deficit in sustained attention within
            schizophrenia, in a Taiwanese cohort.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (residues 1 to 625)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
REFERENCE   9  (residues 1 to 625)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
REFERENCE   10 (residues 1 to 625)
  AUTHORS   Di Matteo,G., Salerno,M., Guarguaglini,G., Di Fiore,B., Palitti,F.
            and Lavia,P.
  TITLE     Interactions with single-stranded and double-stranded DNA-binding
            factors and alternative promoter conformation upon transcriptional
            activation of the Htf9-a/RanBP1 and Htf9-c genes
  JOURNAL   J Biol Chem 273 (1), 495-505 (1998)
   PUBMED   9417108
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX349795.2, BC017184.2 and
            AI539558.1.
            
            On Aug 26, 2003 this sequence version replaced NP_892029.1.
            
            Summary: The protein encoded by this gene is of unknown function.
            However, it is orthologous to the mouse Trmt2a gene and contains an
            RNA methyltransferase domain. Expression of this gene varies during
            the cell cycle, with aberrant expression being a possible biomarker
            in certain breast cancers. Several transcript variants encoding two
            different isoforms have been found for this gene. [provided by
            RefSeq, Apr 2012].
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 both encode the same isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC017184.2, SRR18074968.48248.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.21"
     Protein         1..625
                     /product="tRNA (uracil-5-)-methyltransferase homolog A
                     isoform a"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog A; tRNA
                     methyltransferase 2 homolog A; hpaII tiny fragments locus
                     9c protein; TRM2 tRNA methyltransferase 2 homolog A; mRNA
                     (uracil-5-)-methyltransferase TRMT2A"
                     /calculated_mol_wt=68595
     Region          1..37
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Region          68..146
                     /region_name="RRM_TRMT2A"
                     /note="RNA recognition motif (RRM) found in tRNA
                     (uracil-5-)-methyltransferase homolog A (TRMT2A) and
                     similar proteins; cd12439"
                     /db_xref="CDD:409873"
     Region          145..165
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Region          <178..587
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     Site            378
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Region          594..625
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Site            602
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:18669648,
                     ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q8IZ69.2)"
     CDS             1..625
                     /gene="TRMT2A"
                     /gene_synonym="HTF9C"
                     /coded_by="NM_182984.5:197..2074"
                     /note="isoform a is encoded by transcript variant 2"
                     /db_xref="CCDS:CCDS13774.1"
                     /db_xref="GeneID:27037"
                     /db_xref="HGNC:HGNC:24974"
                     /db_xref="MIM:611151"
ORIGIN      
        1 msenldnegp kpmescgqes ssalscptvs vppaapaale evekegagaa tgpgpqpgly
       61 syirddlfts eifklelqnv prhasfsdvr rflgrfglqp hktklfgqpp cafvtfrsaa
      121 erdkalrvlh galwkgrpls vrlarpkadp marrrrqege seppvtrvad vvtplwtvpy
      181 aeqlerkqle ceqvlqklak eigstnrall pwlleqrhkh nkaccplegv rpspqqteyr
      241 nkceflvgvg vdgedntvgc rlgkykggtc avaapfdtvh ipeatkqvvk afqefirstp
      301 ysaydpetyt ghwkqltvrt srrhqamaia yfhpqklspe elaelktsla qhftagpgra
      361 sgvtclyfve egqrktpsqe glplehvagd rcihedllgl tfrisphaff qvntpaaevl
      421 ytviqdwaql dagsmvldvc cgtgtiglal arkvkrvigv elcpeaveda rvnaqdnels
      481 nvefhcgrae dlvptlvsrl asqhlvaild ppraglhskv ilairraknl rrllyvscnp
      541 raamgnfvdl crapsnrvkg ipfrpvkava vdlfpqtphc emlilferve hpngtgvlgp
      601 hsppaqptpg ppdntlqetg tfpss
//
LOCUS       NP_001380341             306 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA:m(4)X modification enzyme TRM13 homolog isoform 5 [Homo
            sapiens].
ACCESSION   NP_001380341 XP_016856994
VERSION     NP_001380341.1
DBSOURCE    REFSEQ: accession NM_001393412.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 306)
  AUTHORS   Li,H., Dong,H., Xu,B., Xiong,Q.P., Li,C.T., Yang,W.Q., Li,J.,
            Huang,Z.X., Zeng,Q.Y., Wang,E.D. and Liu,R.J.
  TITLE     A dual role of human tRNA methyltransferase hTrmt13 in regulating
            translation and transcription
  JOURNAL   EMBO J 41 (6), e108544 (2022)
   PUBMED   34850409
  REMARK    GeneRIF: A dual role of human tRNA methyltransferase hTrmt13 in
            regulating translation and transcription.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445928.8.
            
            On Feb 9, 2021 this sequence version replaced XP_016856994.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.135259.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p21.2"
     Protein         1..306
                     /product="tRNA:m(4)X modification enzyme TRM13 homolog
                     isoform 5"
                     /EC_number="2.1.1.225"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM13
                     homolog; tRNA [Gm4] methyltransferase; coiled-coil
                     domain-containing protein 76; tRNA methyltransferase 13
                     homolog; coiled-coil domain containing 76; tRNA:m(4)X
                     modification enzyme TRM13 homolog"
                     /calculated_mol_wt=33900
     Region          17..45
                     /region_name="zf-TRM13_CCCH"
                     /note="CCCH zinc finger in TRM13 protein; pfam11722"
                     /db_xref="CDD:463331"
     Region          56..80
                     /region_name="zf-U11-48K"
                     /note="U11-48K-like CHHC zinc finger; pfam05253"
                     /db_xref="CDD:461603"
     Region          151..>259
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     CDS             1..306
                     /gene="TRMT13"
                     /gene_synonym="CCDC76; hTrmt13"
                     /coded_by="NM_001393412.1:7..927"
                     /note="isoform 5 is encoded by transcript variant 5"
                     /db_xref="GeneID:54482"
                     /db_xref="HGNC:HGNC:25502"
ORIGIN      
        1 matsatspha pgfpaegrcg yyvekkkrfc rmvvaagkrf cgehagaaee edarkrilcp
       61 ldpkhtvyed qlakhlkkcn srekpkpdfy iqdinaglrd eteipeqlvp isslseeqle
      121 klikklrkas ealhdalndp kngdsatkhl kqqasilgni enlkllgprr cfvefgagkg
      181 klshwvdial kdaekvhfil vekvttrfkv dgkhrkknsv ferlqidiqh lclnkipvlr
      241 eeklpvvgig khlcgmatdg vslcrpdwsa vaqsrltats asrlqaillp qppellglqt
      301 rattpg
//
LOCUS       NP_001337511             400 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform c [Homo
            sapiens].
ACCESSION   NP_001337511
VERSION     NP_001337511.1
DBSOURCE    REFSEQ: accession NM_001350582.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 400)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 400)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 400)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 400)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 400)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 400)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 400)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 400)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 400)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 400)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (4), as well as variants 3, 5, and
            6, encodes isoform c.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189661.114054.1,
                                           SRR18074967.4019218.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..400
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform c"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=46106
     Region          134..323
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..400
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350582.2:170..1372"
                     /note="isoform c is encoded by transcript variant 4"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mkrtvcaksi felwghgqsp eelysslkny pvekmvpflh sdstykikih tfnktltqee
       61 kikridalef lpfegkvnlk kpqhvfsvle dygldpncip enphniyfgr wiadgqreli
      121 esysvkkrhf igntsmdagl sfimanhgkv kendivfdpf vgtgglliac ahfgayvygt
      181 didyntvhgl gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask pswrkgtyfd
      241 aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf ldllnfaaet
      301 lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm ekvkkfenrd
      361 qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001298266             117 aa            linear   VRT 18-JUN-2025
DEFINITION  CD59 glycoprotein precursor [Oreochromis niloticus].
ACCESSION   NP_001298266 XP_003460314
VERSION     NP_001298266.1
DBSOURCE    REFSEQ: accession NM_001311337.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 117)
  AUTHORS   Gan,Z., Wang,B., Zhou,W., Lu,Y., Zhu,W., Tang,J., Jian,J. and Wu,Z.
  TITLE     Molecular and functional characterization of CD59 from Nile tilapia
            (Oreochromis niloticus) involved in the immune response to
            Streptococcus agalactiae
  JOURNAL   Fish Shellfish Immunol 44 (1), 50-59 (2015)
   PUBMED   25661843
  REMARK    GeneRIF: CD59 was cloned from Nile tilapia (Oreochromis
            niloticus)and the expressed protein was found to have
            complement-inhibitory activity.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KM823662.1.
            
            On Aug 7, 2015 this sequence version replaced XP_003460314.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KM823662.1, GR607910.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767853, SAMN00767854
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..117
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
     Protein         1..117
                     /product="CD59 glycoprotein precursor"
                     /calculated_mol_wt=10877
     sig_peptide     1..21
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2117
     Region          22..92
                     /region_name="TFP_LU_ECD_CD59"
                     /note="extracellular domain (ECD) found in CD59
                     glycoprotein and similar proteins; cd23554"
                     /db_xref="CDD:467084"
     CDS             1..117
                     /gene="cd59a"
                     /gene_synonym="CD59"
                     /coded_by="NM_001311337.1:75..428"
                     /db_xref="GeneID:100705993"
ORIGIN      
        1 mkhslgiclv icstliglgs aircyrckdy tasctkerec syddacltlr erggmtyrqc
       61 mkysdceygr laqmfpqass ftfkccnsdl cnsapssats svigvlasla vmwwcih
//
LOCUS       NP_115666               1058 aa            linear   PRI 18-JUN-2025
DEFINITION  SMC5-SMC6 complex localization factor protein 1 [Homo sapiens].
ACCESSION   NP_115666
VERSION     NP_115666.2
DBSOURCE    REFSEQ: accession NM_032290.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 1058)
  AUTHORS   Oravcova,M., Nie,M., Zilio,N., Maeda,S., Jami-Alahmadi,Y.,
            Lazzerini-Denchi,E., Wohlschlegel,J.A., Ulrich,H.D., Otomo,T. and
            Boddy,M.N.
  TITLE     The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral
            replication centers
  JOURNAL   Elife 11, e79676 (2022)
   PUBMED   36373674
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 1058)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (residues 1 to 1058)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   4  (residues 1 to 1058)
  AUTHORS   Hein,M.Y., Hubner,N.C., Poser,I., Cox,J., Nagaraj,N., Toyoda,Y.,
            Gak,I.A., Weisswange,I., Mansfeld,J., Buchholz,F., Hyman,A.A. and
            Mann,M.
  TITLE     A human interactome in three quantitative dimensions organized by
            stoichiometries and abundances
  JOURNAL   Cell 163 (3), 712-723 (2015)
   PUBMED   26496610
REFERENCE   5  (residues 1 to 1058)
  AUTHORS   Raschle,M., Smeenk,G., Hansen,R.K., Temu,T., Oka,Y., Hein,M.Y.,
            Nagaraj,N., Long,D.T., Walter,J.C., Hofmann,K., Storchova,Z.,
            Cox,J., Bekker-Jensen,S., Mailand,N. and Mann,M.
  TITLE     DNA repair. Proteomics reveals dynamic assembly of repair complexes
            during bypass of DNA cross-links
  JOURNAL   Science 348 (6234), 1253671 (2015)
   PUBMED   25931565
REFERENCE   6  (residues 1 to 1058)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   7  (residues 1 to 1058)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   8  (residues 1 to 1058)
  AUTHORS   Adams,D.J., van der Weyden,L., Gergely,F.V., Arends,M.J., Ng,B.L.,
            Tannahill,D., Kanaar,R., Markus,A., Morris,B.J. and Bradley,A.
  TITLE     BRCTx is a novel, highly conserved RAD18-interacting protein
  JOURNAL   Mol Cell Biol 25 (2), 779-788 (2005)
   PUBMED   15632077
  REMARK    GeneRIF: Results describe the cloning, characterization, and
            targeted mutagenesis of Brctx, a novel gene with a BRCT motif
            [Brctx].
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC025766.4, DR001089.1, BU431750.1, CR936768.1, BC063674.1 and
            AC008534.7.
            
            On May 15, 2008 this sequence version replaced NP_115666.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.135035.1,
                                           SRR1803613.139220.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000265140.10/ ENSP00000265140.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q15"
     Protein         1..1058
                     /product="SMC5-SMC6 complex localization factor protein 1"
                     /note="BRCT domain containing 1; ankyrin repeat
                     domain-containing protein 32; BRCT domain-containing
                     protein 1; ankyrin repeat domain 32; smc5/6 localization
                     factor 1; SMC5-SMC6 complex localization factor 1"
                     /calculated_mol_wt=120920
     Region          5..85
                     /region_name="BRCT_SLF1"
                     /note="BRCT domain of SMC5-SMC6 complex localization
                     factor protein 1 (SLF1) and similar proteins; cd17750"
                     /db_xref="CDD:349381"
     Region          127..198
                     /region_name="BRCT"
                     /note="C-terminal domain of the breast cancer suppressor
                     protein (BRCA1) and related domains; cl00038"
                     /db_xref="CDD:469589"
     Region          410..1058
                     /region_name="NSE5-like domain, mediates interaction with
                     SLF2. /evidence=ECO:0000269|PubMed:36373674"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BQI6.2)"
     Region          <796..>916
                     /region_name="ANKYR"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     COG0666"
                     /db_xref="CDD:440430"
     Region          807..838
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Site            order(808,812..813,816..818,820..821,825,828,838,840,842,
                     846..847,850..852,854..855,859,862,871,874,876,880..881,
                     884..886,888..889,893,896)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:293786"
     Region          840..871
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     Region          874..904
                     /region_name="ANK repeat"
                     /note="ANK repeat [structural motif]"
                     /db_xref="CDD:293786"
     CDS             1..1058
                     /gene="SLF1"
                     /gene_synonym="ANKRD32; BRCTD1; BRCTx; hNSE5"
                     /coded_by="NM_032290.4:98..3274"
                     /db_xref="CCDS:CCDS4071.2"
                     /db_xref="GeneID:84250"
                     /db_xref="HGNC:HGNC:25408"
                     /db_xref="MIM:618467"
ORIGIN      
        1 medgtpkhii qmtgfkmeek ealvklllkl dctfikseky kncthliaer lcksekflaa
       61 caagkwiltk dyiihsaksg rwldettyew gykiekdsry spqmqsapkr wreelkrtga
      121 pgafhrwkvv llvrtdkrsd slirvleagk anvilpkssp sgithviasn arikaekekd
      181 nfkapfypiq ylgdflleke iqndedsqtn svwtehsnee tnkdfrkdag flemkgalre
      241 tmyrtqkemq nhedvnvgsi liqhhkkekf sgsskdlkfv kmrntfgsht yenqkeikkk
      301 dediqrsytl rrkrkkgkes nckkgvehek ikstlrrhiy nrdqkemkns ifaeyakesk
      361 amaiktdvdv veikntlrkh iyraqavryn ciridkqpvy nvevknaefp rgvlnliesl
      421 ieghffkeai eelstlqahy ippvcvlhal lenvlqdnid tfsgryfhil sallhlhppw
      481 kspamsryyl elfqcptcmk gawslvevli rsclfnesfc hqisenigsk vlhltllkff
      541 fnliesevqh lsqklydwsd sqnlkitgka mlleifwsgs etsglltkpv nmllewtiys
      601 hkekfksndv fkhelaylla gilgaaidyw iflglkmgrn vmrhmsddlg syvslscddf
      661 ssqeleific sfssswlqmf vaeavfkklc lqssgsvsse plslqkmvys ylpalgktgv
      721 lgsgkiqvsk kigqrpcfds qrtllmlngt kqkqveglpe lldlnlakcs sslkklkkks
      781 egelscsken cpsvvkkmnf hktnlkgeta lhracinnqv eklilllslp gidinvkdna
      841 gwtplheacn ygntvcvqei lqrcpevdll tqvdgvtplh dalsnghvei gklllqhggp
      901 vllqqrnakg elpldyvvsp qikeelfait kiedtvenfh aqaekhfhyq qlefgsflls
      961 rmllnfcsif dlssefilas kglthlnell mackshkett svhtdwlldl yagniktlqk
     1021 lphilkelpe nlkvcpgvht ealmitlemm crsvmefs
//
LOCUS       NP_001009905             346 aa            linear   PRI 18-JUN-2025
DEFINITION  queuosine-tRNA galactosyltransferase isoform a [Homo sapiens].
ACCESSION   NP_001009905 NP_919264
VERSION     NP_001009905.2
DBSOURCE    REFSEQ: accession NM_001009905.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 346)
  AUTHORS   Zhao,X., Ma,D., Ishiguro,K., Saito,H., Akichika,S., Matsuzawa,I.,
            Mito,M., Irie,T., Ishibashi,K., Wakabayashi,K., Sakaguchi,Y.,
            Yokoyama,T., Mishima,Y., Shirouzu,M., Iwasaki,S., Suzuki,T. and
            Suzuki,T.
  TITLE     Glycosylated queuosines in tRNAs optimize translational rate and
            post-embryonic growth
  JOURNAL   Cell 186 (25), 5517-5535 (2023)
   PUBMED   37992713
REFERENCE   2  (residues 1 to 346)
  AUTHORS   Zheng,H., Li,Y., Ji,C., Li,J., Zhang,J., Yin,G., Xu,J., Ye,X.,
            Wu,M., Zou,X., Gu,S., Xie,Y. and Mao,Y.
  TITLE     Characterization of a cDNA encoding a protein with limited
            similarity to beta1, 3-N-acetylglucosaminyltransferase
  JOURNAL   Mol Biol Rep 31 (3), 171-175 (2004)
   PUBMED   15560372
  REMARK    GeneRIF: beta3-GnTL1 is similar to beta1,
            3-N-acetylglucosaminyltransferase
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130371.4.
            
            On Jan 13, 2021 this sequence version replaced NP_001009905.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY634364.1, AY304503.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000320865.4/ ENSP00000319979.4
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.3"
     Protein         1..346
                     /product="queuosine-tRNA galactosyltransferase isoform a"
                     /EC_number="2.4.1.-"
                     /note="UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 8;
                     UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase-like protein 1;
                     BGnT-like protein 1; UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase like 1;
                     beta3Gn-T-like protein 1;
                     beta1,3-N-acetylglucosaminyltransferase-like protein 1;
                     beta-1,3-Gn-T8"
                     /calculated_mol_wt=39263
     Region          7..225
                     /region_name="beta3GnTL1_like"
                     /note="Beta 1, 3-N-acetylglucosaminyltransferase is
                     essential for the formation of poly-N-acetyllactosamine;
                     cd06913"
                     /db_xref="CDD:133063"
     CDS             1..346
                     /gene="QTGAL"
                     /gene_synonym="3-Gn-T8; B3GNT8; B3GNTL1; beta-1;
                     beta3Gn-T8; beta3GnTL1; BGnT-8"
                     /coded_by="NM_001009905.3:20..1060"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS32778.2"
                     /db_xref="GeneID:146712"
                     /db_xref="HGNC:HGNC:21727"
                     /db_xref="MIM:615337"
ORIGIN      
        1 mqahvsiilp vhnaepwlde clrsvlqqdf egtmelsvfn daskdksgai iekwrvkled
       61 sgvhviiggh dspsprgvgy aknqavaqss gsylcfldsd dvmmpqrvrl qheaavqhps
      121 siigcrvrrd ppnsterytr winqltpeql ltqvftsngp tvimptwfcs rawfshvgpf
      181 neggqgvped llffyehlrk gggvirvdqs lllyrhhpqa athcvletti wthrvrflee
      241 qalprwaaft iwnagkqgrr lyrsltagsq rkvvafcdvd enkirkgfyc hedsqerpkp
      301 ripilhfraa rppfvicvkl dltggafedn lrslhlqegq dflhfs
//
LOCUS       NP_001380343             268 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA:m(4)X modification enzyme TRM13 homolog isoform 7 [Homo
            sapiens].
ACCESSION   NP_001380343
VERSION     NP_001380343.1
DBSOURCE    REFSEQ: accession NM_001393414.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 268)
  AUTHORS   Li,H., Dong,H., Xu,B., Xiong,Q.P., Li,C.T., Yang,W.Q., Li,J.,
            Huang,Z.X., Zeng,Q.Y., Wang,E.D. and Liu,R.J.
  TITLE     A dual role of human tRNA methyltransferase hTrmt13 in regulating
            translation and transcription
  JOURNAL   EMBO J 41 (6), e108544 (2022)
   PUBMED   34850409
  REMARK    GeneRIF: A dual role of human tRNA methyltransferase hTrmt13 in
            regulating translation and transcription.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445928.8.
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p21.2"
     Protein         1..268
                     /product="tRNA:m(4)X modification enzyme TRM13 homolog
                     isoform 7"
                     /EC_number="2.1.1.225"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM13
                     homolog; tRNA [Gm4] methyltransferase; coiled-coil
                     domain-containing protein 76; tRNA methyltransferase 13
                     homolog; coiled-coil domain containing 76; tRNA:m(4)X
                     modification enzyme TRM13 homolog"
                     /calculated_mol_wt=30100
     Region          17..45
                     /region_name="zf-TRM13_CCCH"
                     /note="CCCH zinc finger in TRM13 protein; pfam11722"
                     /db_xref="CDD:463331"
     Region          56..80
                     /region_name="zf-U11-48K"
                     /note="U11-48K-like CHHC zinc finger; pfam05253"
                     /db_xref="CDD:461603"
     Region          151..>260
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     CDS             1..268
                     /gene="TRMT13"
                     /gene_synonym="CCDC76; hTrmt13"
                     /coded_by="NM_001393414.1:7..813"
                     /note="isoform 7 is encoded by transcript variant 7"
                     /db_xref="GeneID:54482"
                     /db_xref="HGNC:HGNC:25502"
ORIGIN      
        1 matsatspha pgfpaegrcg yyvekkkrfc rmvvaagkrf cgehagaaee edarkrilcp
       61 ldpkhtvyed qlakhlkkcn srekpkpdfy iqdinaglrd eteipeqlvp isslseeqle
      121 klikklrkas ealhdalndp kngdsatkhl kqqasilgni enlkllgprr cfvefgagkg
      181 klshwvdial kdaekvhfil vekvttrfkv dgkhrkknsv ferlqidiqh lclnkipvlr
      241 eeklpvvgig khlcgmatgf lvlkkrrk
//
LOCUS       NP_619649                304 aa            linear   PRI 18-JUN-2025
DEFINITION  non-structural maintenance of chromosomes element 3 homolog [Homo
            sapiens].
ACCESSION   NP_619649
VERSION     NP_619649.1
DBSOURCE    REFSEQ: accession NM_138704.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 304)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (residues 1 to 304)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   3  (residues 1 to 304)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (residues 1 to 304)
  AUTHORS   van der Crabben,S.N., Hennus,M.P., McGregor,G.A., Ritter,D.I.,
            Nagamani,S.C., Wells,O.S., Harakalova,M., Chinn,I.K., Alt,A.,
            Vondrova,L., Hochstenbach,R., van Montfrans,J.M.,
            Terheggen-Lagro,S.W., van Lieshout,S., van Roosmalen,M.J.,
            Renkens,I., Duran,K., Nijman,I.J., Kloosterman,W.P., Hennekam,E.,
            Orange,J.S., van Hasselt,P.M., Wheeler,D.A., Palecek,J.J.,
            Lehmann,A.R., Oliver,A.W., Pearl,L.H., Plon,S.E., Murray,J.M. and
            van Haaften,G.
  TITLE     Destabilized SMC5/6 complex leads to chromosome breakage syndrome
            with severe lung disease
  JOURNAL   J Clin Invest 126 (8), 2881-2892 (2016)
   PUBMED   27427983
  REMARK    GeneRIF: NSMCE3 (also known as NDNL2) gene encodes a subunit of the
            SMC5/6 complex that is essential for DNA damage response and
            chromosome segregation
REFERENCE   5  (residues 1 to 304)
  AUTHORS   Hein,M.Y., Hubner,N.C., Poser,I., Cox,J., Nagaraj,N., Toyoda,Y.,
            Gak,I.A., Weisswange,I., Mansfeld,J., Buchholz,F., Hyman,A.A. and
            Mann,M.
  TITLE     A human interactome in three quantitative dimensions organized by
            stoichiometries and abundances
  JOURNAL   Cell 163 (3), 712-723 (2015)
   PUBMED   26496610
REFERENCE   6  (residues 1 to 304)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   7  (residues 1 to 304)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   8  (residues 1 to 304)
  AUTHORS   Andersen,J.S., Lam,Y.W., Leung,A.K., Ong,S.E., Lyon,C.E.,
            Lamond,A.I. and Mann,M.
  TITLE     Nucleolar proteome dynamics
  JOURNAL   Nature 433 (7021), 77-83 (2005)
   PUBMED   15635413
REFERENCE   9  (residues 1 to 304)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (33), 12130-12135 (2004)
   PUBMED   15302935
REFERENCE   10 (residues 1 to 304)
  AUTHORS   Chibuk,T.K., Bischof,J.M. and Wevrick,R.
  TITLE     A necdin/MAGE-like gene in the chromosome 15 autism susceptibility
            region: expression, imprinting, and mapping of the human and mouse
            orthologues
  JOURNAL   BMC Genet 2, 22 (2001)
   PUBMED   11782285
  REMARK    GeneRIF: gene expression, imprinting, and chromosome mapping of
            NDNL2
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC061965.16, AU310582.1 and
            BC053999.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The protein encoded by this gene is part of the SMC5-6
            chromatin reorganizing complex and is a member of the MAGE
            superfamily. This is an intronless gene. [provided by RefSeq, May
            2011].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR1660805.354412.1, DRR138512.517665.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000332303.6/ ENSP00000330694.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q13.1"
     Protein         1..304
                     /product="non-structural maintenance of chromosomes
                     element 3 homolog"
                     /note="necdin-like gene 2; hepatocellular
                     carcinoma-associated protein HCA4; melanoma antigen,
                     family G, 1; necdin-like 2, SMC5-SMC6 complex component;
                     melanoma-associated antigen G1; MAGE-G1 antigen;
                     necdin-like protein 2; hepatocellular carcinoma-associated
                     protein 4; non-SMC element 3 homolog; NSE3 homolog,
                     SMC5-SMC6 complex component"
                     /calculated_mol_wt=34177
     Region          1..82
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96MG7.1)"
     Site            57
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:18669648,
                     ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q96MG7.1)"
     Site            60
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q96MG7.1)"
     Site            64
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:18669648,
                     ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569;
                     propagated from UniProtKB/Swiss-Prot (Q96MG7.1)"
     Region          78..304
                     /region_name="Interaction with NSMCE1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96MG7.1)"
     Region          92..261
                     /region_name="MAGE"
                     /note="MAGE homology domain; pfam01454"
                     /db_xref="CDD:426270"
     Region          285..304
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96MG7.1)"
     CDS             1..304
                     /gene="NSMCE3"
                     /gene_synonym="HCA4; LICS; MAGEG1; MAGEL3; NDNL2; NSE3"
                     /coded_by="NM_138704.4:118..1032"
                     /db_xref="CCDS:CCDS10023.1"
                     /db_xref="GeneID:56160"
                     /db_xref="HGNC:HGNC:7677"
                     /db_xref="MIM:608243"
ORIGIN      
        1 mlqkprnrgr sggqaerdrd wshsgnpgas ragedarvlr dgfaeeapst srgpggsqgs
       61 qgpspqgarr aqaapavgpr sqkqlelkvs elvqfllikd qkkipikrad ilkhvigdyk
      121 difpdlfkra aerlqyvfgy klvelepksn tyilintlep veedaemrgd qgtpttgllm
      181 ivlglifmkg ntiketeawd flrrlgvypt kkhlifgdpk klitedfvrq ryleyrriph
      241 tdpvdyefqw gprtnletsk mkvlkfvakv hnqdpkdwpa qycealadee nrarpqpsgp
      301 apss
//
LOCUS       NP_073564                625 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog A isoform a [Homo
            sapiens].
ACCESSION   NP_073564
VERSION     NP_073564.3
DBSOURCE    REFSEQ: accession NM_022727.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 625)
  AUTHORS   Witzenberger,M., Burczyk,S., Settele,D., Mayer,W., Welp,L.M.,
            Heiss,M., Wagner,M., Monecke,T., Janowski,R., Carell,T., Urlaub,H.,
            Hauck,S.M., Voigt,A. and Niessing,D.
  TITLE     Human TRMT2A methylates tRNA and contributes to translation
            fidelity
  JOURNAL   Nucleic Acids Res 51 (16), 8691-8710 (2023)
   PUBMED   37395448
  REMARK    GeneRIF: Human TRMT2A methylates tRNA and contributes to
            translation fidelity.
REFERENCE   2  (residues 1 to 625)
  AUTHORS   Dai,W., Li,A., Yu,N.J., Nguyen,T., Leach,R.W., Wuhr,M. and
            Kleiner,R.E.
  TITLE     Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated
            dihydrouridylation
  JOURNAL   Nat Chem Biol 17 (11), 1178-1187 (2021)
   PUBMED   34556860
REFERENCE   3  (residues 1 to 625)
  AUTHORS   Pereira,M., Ribeiro,D.R., Pinheiro,M.M., Ferreira,M., Kellner,S.
            and Soares,A.R.
  TITLE     m5U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation
            of tRNA-Derived Small RNAs
  JOURNAL   Int J Mol Sci 22 (6), 2941 (2021)
   PUBMED   33799331
  REMARK    GeneRIF: m(5)U54 tRNA Hypomodification by Lack of TRMT2A Drives the
            Generation of tRNA-Derived Small RNAs.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 625)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (residues 1 to 625)
  AUTHORS   Cheng,Q.Y., Xiong,J., Ma,C.J., Dai,Y., Ding,J.H., Liu,F.L.,
            Yuan,B.F. and Feng,Y.Q.
  TITLE     Chemical tagging for sensitive determination of uridine
            modifications in RNA
  JOURNAL   Chem Sci 11 (7), 1878-1891 (2020)
   PUBMED   34123281
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 625)
  AUTHORS   Hicks,D.G., Janarthanan,B.R., Vardarajan,R., Kulkarni,S.A.,
            Khoury,T., Dim,D., Budd,G.T., Yoder,B.J., Tubbs,R., Schreeder,M.T.,
            Estopinal,N.C., Beck,R.A., Wang,Y., Ring,B.Z., Seitz,R.S. and
            Ross,D.T.
  TITLE     The expression of TRMT2A, a novel cell cycle regulated protein,
            identifies a subset of breast cancer patients with HER2
            over-expression that are at an increased risk of recurrence
  JOURNAL   BMC Cancer 10, 108 (2010)
   PUBMED   20307320
  REMARK    GeneRIF: TRMT2A staining showed a strong correlation with
            likelihood of recurrence at five years in 67 HER2+ breast cancer.
            Publication Status: Online-Only
REFERENCE   7  (residues 1 to 625)
  AUTHORS   Liu,Y.L., Fann,C.S., Liu,C.M., Chang,C.C., Yang,W.C., Wu,J.Y.,
            Hung,S.I., Chan,H.Y., Chen,J.J., Hsieh,M.H., Hwang,T.J.,
            Faraone,S.V., Tsuang,M.T., Chen,W.J. and Hwu,H.G.
  TITLE     HTF9C gene of 22q11.21 region associates with schizophrenia having
            deficit-sustained attention
  JOURNAL   Psychiatr Genet 17 (6), 333-338 (2007)
   PUBMED   18075473
  REMARK    GeneRIF: Single nucleotid polymorphisms of this gene may be
            associated with a deficit in sustained attention within
            schizophrenia, in a Taiwanese cohort.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (residues 1 to 625)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
REFERENCE   9  (residues 1 to 625)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
REFERENCE   10 (residues 1 to 625)
  AUTHORS   Di Matteo,G., Salerno,M., Guarguaglini,G., Di Fiore,B., Palitti,F.
            and Lavia,P.
  TITLE     Interactions with single-stranded and double-stranded DNA-binding
            factors and alternative promoter conformation upon transcriptional
            activation of the Htf9-a/RanBP1 and Htf9-c genes
  JOURNAL   J Biol Chem 273 (1), 495-505 (1998)
   PUBMED   9417108
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX349795.2, AC006547.9,
            BC017184.2 and AI539558.1.
            
            On Aug 12, 2004 this sequence version replaced NP_073564.2.
            
            Summary: The protein encoded by this gene is of unknown function.
            However, it is orthologous to the mouse Trmt2a gene and contains an
            RNA methyltransferase domain. Expression of this gene varies during
            the cell cycle, with aberrant expression being a possible biomarker
            in certain breast cancers. Several transcript variants encoding two
            different isoforms have been found for this gene. [provided by
            RefSeq, Apr 2012].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (a). Variants 1 and 2 both encode the same isoform (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC108251.1, CR456354.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000252136.12/ ENSP00000252136.7
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.21"
     Protein         1..625
                     /product="tRNA (uracil-5-)-methyltransferase homolog A
                     isoform a"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog A; tRNA
                     methyltransferase 2 homolog A; hpaII tiny fragments locus
                     9c protein; TRM2 tRNA methyltransferase 2 homolog A; mRNA
                     (uracil-5-)-methyltransferase TRMT2A"
                     /calculated_mol_wt=68595
     Region          1..37
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Region          68..146
                     /region_name="RRM_TRMT2A"
                     /note="RNA recognition motif (RRM) found in tRNA
                     (uracil-5-)-methyltransferase homolog A (TRMT2A) and
                     similar proteins; cd12439"
                     /db_xref="CDD:409873"
     Region          145..165
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Region          <178..587
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     Site            378
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Region          594..625
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IZ69.2)"
     Site            602
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:18669648,
                     ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q8IZ69.2)"
     CDS             1..625
                     /gene="TRMT2A"
                     /gene_synonym="HTF9C"
                     /coded_by="NM_022727.6:321..2198"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS13774.1"
                     /db_xref="GeneID:27037"
                     /db_xref="HGNC:HGNC:24974"
                     /db_xref="MIM:611151"
ORIGIN      
        1 msenldnegp kpmescgqes ssalscptvs vppaapaale evekegagaa tgpgpqpgly
       61 syirddlfts eifklelqnv prhasfsdvr rflgrfglqp hktklfgqpp cafvtfrsaa
      121 erdkalrvlh galwkgrpls vrlarpkadp marrrrqege seppvtrvad vvtplwtvpy
      181 aeqlerkqle ceqvlqklak eigstnrall pwlleqrhkh nkaccplegv rpspqqteyr
      241 nkceflvgvg vdgedntvgc rlgkykggtc avaapfdtvh ipeatkqvvk afqefirstp
      301 ysaydpetyt ghwkqltvrt srrhqamaia yfhpqklspe elaelktsla qhftagpgra
      361 sgvtclyfve egqrktpsqe glplehvagd rcihedllgl tfrisphaff qvntpaaevl
      421 ytviqdwaql dagsmvldvc cgtgtiglal arkvkrvigv elcpeaveda rvnaqdnels
      481 nvefhcgrae dlvptlvsrl asqhlvaild ppraglhskv ilairraknl rrllyvscnp
      541 raamgnfvdl crapsnrvkg ipfrpvkava vdlfpqtphc emlilferve hpngtgvlgp
      601 hsppaqptpg ppdntlqetg tfpss
//
LOCUS       NP_060085                385 aa            linear   PRI 18-JUN-2025
DEFINITION  non-structural maintenance of chromosomes element 4 homolog A
            isoform 1 [Homo sapiens].
ACCESSION   NP_060085
VERSION     NP_060085.2
DBSOURCE    REFSEQ: accession NM_017615.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 385)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (residues 1 to 385)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (residues 1 to 385)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   4  (residues 1 to 385)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   5  (residues 1 to 385)
  AUTHORS   van der Crabben,S.N., Hennus,M.P., McGregor,G.A., Ritter,D.I.,
            Nagamani,S.C., Wells,O.S., Harakalova,M., Chinn,I.K., Alt,A.,
            Vondrova,L., Hochstenbach,R., van Montfrans,J.M.,
            Terheggen-Lagro,S.W., van Lieshout,S., van Roosmalen,M.J.,
            Renkens,I., Duran,K., Nijman,I.J., Kloosterman,W.P., Hennekam,E.,
            Orange,J.S., van Hasselt,P.M., Wheeler,D.A., Palecek,J.J.,
            Lehmann,A.R., Oliver,A.W., Pearl,L.H., Plon,S.E., Murray,J.M. and
            van Haaften,G.
  TITLE     Destabilized SMC5/6 complex leads to chromosome breakage syndrome
            with severe lung disease
  JOURNAL   J Clin Invest 126 (8), 2881-2892 (2016)
   PUBMED   27427983
REFERENCE   6  (residues 1 to 385)
  AUTHORS   Doyle,J.M., Gao,J., Wang,J., Yang,M. and Potts,P.R.
  TITLE     MAGE-RING protein complexes comprise a family of E3 ubiquitin
            ligases
  JOURNAL   Mol Cell 39 (6), 963-974 (2010)
   PUBMED   20864041
REFERENCE   7  (residues 1 to 385)
  AUTHORS   Taylor,E.M., Copsey,A.C., Hudson,J.J., Vidot,S. and Lehmann,A.R.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   8  (residues 1 to 385)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   9  (residues 1 to 385)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   10 (residues 1 to 385)
  AUTHORS   Hu,B., Liao,C., Millson,S.H., Mollapour,M., Prodromou,C.,
            Pearl,L.H., Piper,P.W. and Panaretou,B.
  TITLE     Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex
  JOURNAL   Mol Microbiol 55 (6), 1735-1750 (2005)
   PUBMED   15752197
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA567626.1, AK000010.1 and AL731566.7.
            
            On Nov 24, 2009 this sequence version replaced NP_060085.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK000010.1, AK222487.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000369023.8/ ENSP00000358019.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.13"
     Protein         1..385
                     /product="non-structural maintenance of chromosomes
                     element 4 homolog A isoform 1"
                     /note="non-structural maintenance of chromosomes element 4
                     homolog A; non-SMC element 4 homolog A; NSE4 homolog A,
                     SMC5-SMC6 complex component; NSE4 homolog, SMC5-SMC6
                     complex component A"
                     /calculated_mol_wt=44170
     Region          1..69
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NXX6.2)"
     Region          133..187
                     /region_name="Nse4-Nse3_bdg"
                     /note="Binding domain of Nse4/EID3 to Nse3-MAGE;
                     pfam15412"
                     /db_xref="CDD:464708"
     Region          285..374
                     /region_name="Nse4_C"
                     /note="Nse4 C-terminal; pfam08743"
                     /db_xref="CDD:462585"
     Site            345
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:17525332; propagated from
                     UniProtKB/Swiss-Prot (Q9NXX6.2)"
     Site            377
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17525332; propagated from
                     UniProtKB/Swiss-Prot (Q9NXX6.2)"
     CDS             1..385
                     /gene="NSMCE4A"
                     /gene_synonym="C10orf86; NS4EA; NSE4A"
                     /coded_by="NM_017615.3:53..1210"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS7624.1"
                     /db_xref="GeneID:54780"
                     /db_xref="HGNC:HGNC:25935"
                     /db_xref="MIM:612987"
ORIGIN      
        1 msgdssgrgp egrgrgrdph rdrtrsrsrs rsplsprsrr gsarerreap erpsledtep
       61 sdsgdemmdp asleaeadqg lcrqirhqyr alinsvqqnr edilnagdkl tevleeantl
      121 fnevsrarea vldahflvla sdlgkekakq lrsdlssfdm lryvetllth mgvnpleaee
      181 lirdedspdf efivydswki tgrtaentfn kthtfhfllg siygecpvpk prvdrprkvp
      241 viqeerampa qlrrmeeshq eatekeveri lgllqtyfre dpdtpmsffd fvvdphsfpr
      301 tvenifhvsf iirdgfarir ldqdrlpvie pvsineeneg fehntqvrnq giialsyrdw
      361 eeivktfeis epvitpsqrq qkpsa
//
LOCUS       NP_001333844             642 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein 429 isoform c [Homo sapiens].
ACCESSION   NP_001333844 XP_016882243
VERSION     NP_001333844.1
DBSOURCE    REFSEQ: accession NM_001346915.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 642)
  AUTHORS   Kim,H., Ramsay,E., Lee,H., Wahl,S. and Dionne,R.A.
  TITLE     Genome-wide association study of acute post-surgical pain in humans
  JOURNAL   Pharmacogenomics 10 (2), 171-179 (2009)
   PUBMED   19207018
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   2  (residues 1 to 642)
  AUTHORS   Abrink,M., Aveskogh,M. and Hellman,L.
  TITLE     Isolation of cDNA clones for 42 different Kruppel-related zinc
            finger proteins expressed in the human monoblast cell line U-937
  JOURNAL   DNA Cell Biol 14 (2), 125-136 (1995)
   PUBMED   7865130
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010615.9.
            
            On Nov 8, 2016 this sequence version replaced XP_016882243.1.
            
            Transcript Variant: This variant (5), as well as variants 3 and 4,
            encodes isoform c.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.263117.1,
                                           SRR1803616.13502.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p12"
     Protein         1..642
                     /product="zinc finger protein 429 isoform c"
                     /calculated_mol_wt=74306
     Region          <1..31
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          115..135
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          143..163
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          171..191
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          197..592
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          199..219
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          227..247
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          255..275
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          283..303
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(288,290,292,294..295,298..299,302,316,318,322..323,
                     326..327,330,344,346,348,350..351,354..355,358)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          311..331
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          339..359
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          370..387
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          395..415
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(400,402,404,406..407,410..411,414,428,430,434..435,
                     438..439,442,456,458,460,462..463,466..467,470)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          423..443
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          451..471
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          479..499
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          507..527
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(512,514,516,518..519,522..523,526,540,542,546..547,
                     550..551,554,568,570,572,574..575,578..579,582)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          535..555
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          563..583
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          591..611
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..642
                     /gene="ZNF429"
                     /coded_by="NM_001346915.2:356..2284"
                     /note="isoform c is encoded by transcript variant 5"
                     /db_xref="GeneID:353088"
                     /db_xref="HGNC:HGNC:20817"
                     /db_xref="MIM:621242"
ORIGIN      
        1 mlenyrnlvf lgiavskpdl itclekekep ckmkrhemvd eppvvcshfa edfwpeqdik
       61 dsfqkvtlrr ydkrghenlq lrkgyktvgd cklykggyng lnqcltltqs kmyhcdiyvk
      121 vfyafsnadr yktrhtgkkp fqckkcgksf cmlsqltqhk kihirentyr ckefgnafnq
      181 ssaltnhkri yvgekhyrce ecgkafnhys tltnhkriht gekpykckec gkafsrystl
      241 tthkrihsge kpykcdecgk tfsisstftk hkiihteekp ykckecgkaf nrsstltshk
      301 rihtgekpyk ceecgkafnw sstltkhkvi htgekpykce ecgkafnqss rltrhkkiht
      361 geepykfekc grvftcsstl tqdkkihtge kpynceecgk vftysstltr hkrihteekp
      421 ykcnecgkaf nrsshltshr rihtgekpyk ceecgkafkq ssnlnshkki hsgekpykce
      481 ecgkafilss rltqhkkiht gekpykceec gkafnrssrl tqhkkihtge kpykckqcdk
      541 afthssnlss hkkihsgekp ykceecgkaf nrssrltqhk kihtrekpyk ceecakaftr
      601 ssrltqhkki hrmgvvahac npstlggrgg ritrsgdrdr pg
//
LOCUS       NP_001358203             526 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein Helios isoform 1 [Homo sapiens].
ACCESSION   NP_001358203 XP_011509116
VERSION     NP_001358203.1
DBSOURCE    REFSEQ: accession NM_001371274.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 526)
  AUTHORS   Velde,H.M., Vaseghi-Shanjani,M., Smits,J.J., Ramakrishnan,G.,
            Oostrik,J., Wesdorp,M., Astuti,G., Yntema,H.G., Hoefsloot,L.,
            Lanting,C.P., Huynen,M.A., Lehman,A., Turvey,S.E., Pennings,R.J.E.
            and Kremer,H.
  CONSRTM   DOOFNL Consortium
  TITLE     Exome variant prioritization in a large cohort of hearing-impaired
            individuals indicates IKZF2 to be associated with non-syndromic
            hearing loss and guides future research of unsolved cases
  JOURNAL   Hum Genet 143 (11), 1379-1399 (2024)
   PUBMED   39406892
REFERENCE   2  (residues 1 to 526)
  AUTHORS   Lukasik,M., Telec,M., Kazmierski,R., Wojtasz,I.,
            Andrzejewska-Gorczynska,N., Kociemba,W., Dworacki,G., Kozubski,W.P.
            and Frydrychowicz,M.
  TITLE     Temporal changes in regulatory T cell subsets defined by the
            transcription factor Helios in stroke and their potential role in
            stroke-associated infection: a prospective case-control study
  JOURNAL   J Neuroinflammation 20 (1), 275 (2023)
   PUBMED   37996909
  REMARK    GeneRIF: Temporal changes in regulatory T cell subsets defined by
            the transcription factor Helios in stroke and their potential role
            in stroke-associated infection: a prospective case-control study.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 526)
  AUTHORS   Mohajeri,A., Vaseghi-Shanjani,M., Rosenfeld,J.A., Yang,G.X., Lu,H.,
            Sharma,M., Lin,S., Salman,A., Waqas,M., Sababi Azamian,M.,
            Worley,K.C., Del Bel,K.L., Kozak,F.K., Rahmanian,R., Biggs,C.M.,
            Hildebrand,K.J., Lalani,S.R., Nicholas,S.K., Scott,D.A.,
            Mostafavi,S., van Karnebeek,C., Henkelman,E., Halparin,J.,
            Yang,C.L., Armstrong,L., Turvey,S.E. and Lehman,A.
  CONSRTM   Undiagnosed Diseases Network; Care4Rare Canada Consortium
  TITLE     Dominant negative variants in IKZF2 cause ICHAD syndrome, a new
            disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay
  JOURNAL   J Med Genet 60 (11), 1092-1104 (2023)
   PUBMED   37316189
  REMARK    GeneRIF: Dominant negative variants in IKZF2 cause ICHAD syndrome,
            a new disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay.
REFERENCE   4  (residues 1 to 526)
  AUTHORS   Tarighi,M., Shahbazi,M., Saadat,P., Daraei,A., Alizadeh Khatir,A.,
            Rahimifard,K. and Mohammadnia-Afrouzi,M.
  TITLE     Decreased frequency of regulatory T cells and level of helios gene
            expression in secondary progressive multiple sclerosis patients:
            Evidence about the development of multiple sclerosis
  JOURNAL   Int Immunopharmacol 116, 109797 (2023)
   PUBMED   36738680
  REMARK    GeneRIF: Decreased frequency of regulatory T cells and level of
            helios gene expression in secondary progressive multiple sclerosis
            patients: Evidence about the development of multiple sclerosis.
REFERENCE   5  (residues 1 to 526)
  AUTHORS   Zhang,H., Jadhav,R.R., Cao,W., Goronzy,I.N., Zhao,T.V., Jin,J.,
            Ohtsuki,S., Hu,Z., Morales,J., Greenleaf,W.J., Weyand,C.M. and
            Goronzy,J.J.
  TITLE     Aging-associated HELIOS deficiency in naive CD4+ T cells alters
            chromatin remodeling and promotes effector cell responses
  JOURNAL   Nat Immunol 24 (1), 96-109 (2023)
   PUBMED   36510022
  REMARK    GeneRIF: Aging-associated HELIOS deficiency in naive CD4[+] T cells
            alters chromatin remodeling and promotes effector cell responses.
REFERENCE   6  (residues 1 to 526)
  AUTHORS   Nakase,K., Ishimaru,F., Fujii,K., Tabayashi,T., Kozuka,T.,
            Sezaki,N., Matsuo,Y. and Harada,M.
  TITLE     Overexpression of novel short isoforms of Helios in a patient with
            T-cell acute lymphoblastic leukemia
  JOURNAL   Exp Hematol 30 (4), 313-317 (2002)
   PUBMED   11937265
  REMARK    GeneRIF: Novel short isoforms of Helios are overexpressed in a
            patient with T-cell acute lymphoblastic leukemia and may contribute
            to the development of T-cell malignancies. Data for unaltered
            Helios indicates tumor suppressor function.
REFERENCE   7  (residues 1 to 526)
  AUTHORS   Perdomo,J., Holmes,M., Chong,B. and Crossley,M.
  TITLE     Eos and pegasus, two members of the Ikaros family of proteins with
            distinct DNA binding activities
  JOURNAL   J Biol Chem 275 (49), 38347-38354 (2000)
   PUBMED   10978333
REFERENCE   8  (residues 1 to 526)
  AUTHORS   Hosokawa,Y., Maeda,Y. and Seto,M.
  TITLE     Human Helios, an Ikaros-related zinc finger DNA binding protein:
            cDNA cloning and tissue expression pattern
  JOURNAL   Immunogenetics 50 (1-2), 106-108 (1999)
   PUBMED   10541817
REFERENCE   9  (residues 1 to 526)
  AUTHORS   Kelley,C.M., Ikeda,T., Koipally,J., Avitahl,N., Wu,L.,
            Georgopoulos,K. and Morgan,B.A.
  TITLE     Helios, a novel dimerization partner of Ikaros expressed in the
            earliest hematopoietic progenitors
  JOURNAL   Curr Biol 8 (9), 508-515 (1998)
   PUBMED   9560339
REFERENCE   10 (residues 1 to 526)
  AUTHORS   Hahm,K., Cobb,B.S., McCarty,A.S., Brown,K.E., Klug,C.A., Lee,R.,
            Akashi,K., Weissman,I.L., Fisher,A.G. and Smale,S.T.
  TITLE     Helios, a T cell-restricted Ikaros family member that
            quantitatively associates with Ikaros at centromeric
            heterochromatin
  JOURNAL   Genes Dev 12 (6), 782-796 (1998)
   PUBMED   9512513
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC079610.4, AC013736.9 and
            AC108066.3.
            
            On Jul 6, 2019 this sequence version replaced XP_011509116.1.
            
            Summary: This gene encodes a member of the Ikaros family of
            zinc-finger proteins. Three members of this protein family (Ikaros,
            Aiolos and Helios) are hematopoietic-specific transcription factors
            involved in the regulation of lymphocyte development. This protein
            forms homo- or hetero-dimers with other Ikaros family members, and
            is thought to function predominantly in early hematopoietic
            development. Multiple transcript variants encoding different
            isoforms have been found for this gene, but the biological validity
            of some variants has not been determined. [provided by RefSeq, Jul
            2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038192.1483446.1,
                                           SRR14038191.1770697.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..526
                     /product="zinc finger protein Helios isoform 1"
                     /note="zinc finger protein, subfamily 1A, 2 (Helios); zinc
                     finger DNA binding protein Helios; zinc finger protein
                     Helios; ikaros family zinc finger protein 2"
                     /calculated_mol_wt=59443
     Region          28..91
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            56
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            78
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Site            79
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Region          114..134
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(119,121,123,125..126,129..130,133,147,149,153..154,
                     157..158,161,175,177,179,181..182,185..186,189)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          127..151
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          142..162
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          154..179
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          170..190
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          186..207
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          198..219
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            288
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:19608861; propagated from
                     UniProtKB/Swiss-Prot (Q9UKS7.2)"
     Region          370..435
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKS7.2)"
     CDS             1..526
                     /gene="IKZF2"
                     /gene_synonym="ANF1A2; HELIOS; ICHAD; IMDIA; ZNF1A2;
                     ZNFN1A2"
                     /coded_by="NM_001371274.1:347..1927"
                     /note="isoform 1 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS2395.1"
                     /db_xref="GeneID:22807"
                     /db_xref="HGNC:HGNC:13177"
                     /db_xref="MIM:606234"
ORIGIN      
        1 meteaidgyi tcdnelsper ehsnmaidlt sstpngqhas pshmtstnsv klemqsdeec
       61 drkplsrede irghdegssl eepliessev adnrkvqelq geggirlpng klkcdvcgmv
      121 cigpnvlmvh krshtgerpf hcnqcgasft qkgnllrhik lhsgekpfkc pfcsyacrrr
      181 daltghlrth svgkphkcny cgrsykqrss leehkerchn ylqnvsmeaa gqvmshhvpp
      241 medckeqepi mdnnislvpf erpavieklt gnmgkrksst pqkfvgeklm rfsypdihfd
      301 mnltyekeae lmqshmmdqa innaitylga ealhplmqhp pstiaevapv issaysqvyh
      361 pnrierpisr etadshennm dgpislirpk srpqereasp snscldstds esshddhqsy
      421 qghpalnpkr kqspaymked vkaldttkap kgslkdiykv fngegeqira fkcehcrvlf
      481 ldhvmytihm gchgyrdple cnicgyrsqd ryefsshivr gehtfh
//
LOCUS       NP_001161443             459 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog B isoform b [Homo
            sapiens].
ACCESSION   NP_001161443
VERSION     NP_001161443.1
DBSOURCE    REFSEQ: accession NM_001167971.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 459)
  AUTHORS   Liu,Y., He,X., Yuan,Y., Li,B., Liu,Z., Li,W., Li,K., Tan,S.,
            Zhu,Q., Tang,Z., Han,F., Wu,Z., Shen,L., Jiang,H., Tang,B., Qiu,J.,
            Hu,Z. and Wang,J.
  TITLE     Association of TRMT2B gene variants with juvenile amyotrophic
            lateral sclerosis
  JOURNAL   Front Med 18 (1), 68-80 (2024)
   PUBMED   37874476
  REMARK    GeneRIF: Association of TRMT2B gene variants with juvenile
            amyotrophic lateral sclerosis.
REFERENCE   2  (residues 1 to 459)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   3  (residues 1 to 459)
  AUTHORS   Dai,W., Li,A., Yu,N.J., Nguyen,T., Leach,R.W., Wuhr,M. and
            Kleiner,R.E.
  TITLE     Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated
            dihydrouridylation
  JOURNAL   Nat Chem Biol 17 (11), 1178-1187 (2021)
   PUBMED   34556860
REFERENCE   4  (residues 1 to 459)
  AUTHORS   Powell,C.A. and Minczuk,M.
  TITLE     TRMT2B is responsible for both tRNA and rRNA m5U-methylation in
            human mitochondria
  JOURNAL   RNA Biol 17 (4), 451-462 (2020)
   PUBMED   31948311
  REMARK    GeneRIF: TRMT2B is responsible for both tRNA and rRNA
            m(5)U-methylation in human mitochondria.
REFERENCE   5  (residues 1 to 459)
  AUTHORS   Carter,J.M., Emmett,W., Mozos,I.R., Kotter,A., Helm,M., Ule,J. and
            Hussain,S.
  TITLE     FICC-Seq: a method for enzyme-specified profiling of
            methyl-5-uridine in cellular RNA
  JOURNAL   Nucleic Acids Res 47 (19), e113 (2019)
   PUBMED   31361898
REFERENCE   6  (residues 1 to 459)
  AUTHORS   Lee,S.Y., Kang,M.G., Park,J.S., Lee,G., Ting,A.Y. and Rhee,H.W.
  TITLE     APEX Fingerprinting Reveals the Subcellular Localization of
            Proteins of Interest
  JOURNAL   Cell Rep 15 (8), 1837-1847 (2016)
   PUBMED   27184847
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA454040.1, AL832849.1,
            BG747665.1 and Z97985.16.
            
            Summary: This gene encodes a homolog of the TRM2 gene in S.
            cerevisiae. The yeast gene encodes a tRNA methyltransferase that
            plays a role in tRNA maturation. The yeast protein also has
            endo-exonuclease activity and may be involved in DNA double strand
            break repair. Alternative splicing results in multiple transcripts
            encoding different isoforms. [provided by RefSeq, Nov 2009].
            
            Transcript Variant: This variant (3) differs in the 5' UTR and
            lacks an in-frame exon in the coding region, compared to variant 1.
            It encodes isoform b, which is shorter than isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AL832849.1, SRR14372080.4182793.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.1"
     Protein         1..459
                     /product="tRNA (uracil-5-)-methyltransferase homolog B
                     isoform b"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog; TRM2
                     homolog; tRNA (uracil(54)-C(5))-methyltransferase homolog;
                     TRM2 tRNA methyltransferase 2 homolog B; TRM2 homolog B;
                     rRNA (uracil-5-)-methyltransferase TRMT2B; tRNA
                     (uracil-5-)-methyltransferase homolog B"
                     /calculated_mol_wt=51354
     Region          <256..458
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     CDS             1..459
                     /gene="TRMT2B"
                     /gene_synonym="CXorf34; dJ341D10.3"
                     /coded_by="NM_001167971.2:525..1904"
                     /note="isoform b is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS55464.1"
                     /db_xref="GeneID:79979"
                     /db_xref="HGNC:HGNC:25748"
                     /db_xref="MIM:301128"
ORIGIN      
        1 maglkrrvpl hslryfismv glfskpgllp wyarnppgws qlflgtvckg dftrviatkc
       61 qkgqksqkkp shlgpldgsw qerladvvtp lwrlsyeeql kpvingyrnk stfsvnrgpd
      121 gnpktvgfyl gtwrdgnvvc vqsnhlknip ekhsqvaqyy evflrqsple pclvfheggy
      181 wreltvrtns qghtmaiitf hpqklsqeel hvqkeivkef firgpgaacg ltslyfqest
      241 mtrcshqqsp yqllfgepyi feellslkir ispdaffqin tagaemlyrt vgeltgvnsd
      301 tilldiccgt gviglslaqh tsrvlgiell eqavedarwt aafngitnse fhtgqaekil
      361 pgllkskedg qsivavvnpa raglhykviq airnfraiht lvfvscklhg estrnvielc
      421 cppdpakkll gepfvlqqav pvdlfphtph celvllftr
//
LOCUS       NP_001266539             621 aa            linear   VRT 18-JUN-2025
DEFINITION  putative ATP-dependent RNA helicase DDX4 [Oreochromis niloticus].
ACCESSION   NP_001266539 XP_003440976
VERSION     NP_001266539.1
DBSOURCE    REFSEQ: accession NM_001279610.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 621)
  AUTHORS   Kobayashi,T., Kajiura-Kobayashi,H. and Nagahama,Y.
  TITLE     Two isoforms of vasa homologs in a teleost fish: their differential
            expression during germ cell differentiation
  JOURNAL   Mech Dev 111 (1-2), 167-171 (2002)
   PUBMED   11804791
REFERENCE   2  (residues 1 to 621)
  AUTHORS   Kobayashi,T., Kajiura-Kobayashi,H. and Nagahama,Y.
  TITLE     Differential expression of vasa homologue gene in the germ cells
            during oogenesis and spermatogenesis in a teleost fish, tilapia,
            Oreochromis niloticus
  JOURNAL   Mech Dev 99 (1-2), 139-142 (2000)
   PUBMED   11091081
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB051835.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003440976.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB051835.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2482243, SAMEA2482244
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG5"
                     /linkage_group="LG5"
     Protein         1..621
                     /product="putative ATP-dependent RNA helicase DDX4"
                     /EC_number="3.6.4.13"
                     /note="vasa; ATP-dependent RNA helicase DDX4"
                     /calculated_mol_wt=67521
     Region          141..404
                     /region_name="DEADc_DDX4"
                     /note="DEAD-box helicase domain of DEAD box protein 4;
                     cd18052"
                     /db_xref="CDD:350810"
     Site            order(163,173,185,203,205..207,210,228..234,341..342,377)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:350810"
     Site            order(268..270,296..297,317..320,323,345,351)
                     /site_type="other"
                     /note="RNA binding site [nucleotide binding]"
                     /db_xref="CDD:350810"
     Region          410..539
                     /region_name="SF2_C_DEAD"
                     /note="C-terminal helicase domain of the DEAD box
                     helicases; cd18787"
                     /db_xref="CDD:350174"
     Site            order(498,500,525,528..529)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:350174"
     CDS             1..621
                     /gene="ddx4"
                     /gene_synonym="vas; vas-s"
                     /coded_by="NM_001279610.1:48..1913"
                     /db_xref="GeneID:100534408"
ORIGIN      
        1 mdeweeqeta tsgtcaltsd tstggtqgdf wnsdhgefqg grggrgrgrg gfknsffsdg
       61 dgqnntaers sfsrrggran eedgdnknvs rgrrrgrggg eqggrsgfgg gyrgkdeksl
      121 lkargypaen adasdrprvt yvppppsede esifshyesg vnfdkydeil vdvsgtnppp
      181 aimtfdeaal ceslkrnvsk sgyvkptpvq khgipiisag rdlmacaqtg sgktaafllp
      241 ilqqlmadga aascfsemqe pdaiivaptr elinqiylea rkfaygtcvr pvvvyggvst
      301 ghqirdllrg cnvlcgtpgr lldmigrgkv gltkvrylvl deadrmldmg fepdmrrlvg
      361 spgmpskenr qtlmfsatfp ediqrlaadf lktdylflav givggacsdv eqtfvqvtkf
      421 akreqlidll kstgsertmv fvetkrqadf iatilcqekf pttsihgdre qwqreqalgd
      481 frsgkcsvlv atsvgargld ipdvqfvvnf dlpnnideyv hrigrtgrcg ntgravsfyd
      541 pgadselars lvtilskaqq evpswleefa fsghspsgfn pprkhfastd lrkgpqggff
      601 qdgsvtsqla aqtaaddeew e
//
LOCUS       NP_061956                481 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA:m(4)X modification enzyme TRM13 homolog isoform 1 [Homo
            sapiens].
ACCESSION   NP_061956
VERSION     NP_061956.2
DBSOURCE    REFSEQ: accession NM_019083.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 481)
  AUTHORS   Li,H., Dong,H., Xu,B., Xiong,Q.P., Li,C.T., Yang,W.Q., Li,J.,
            Huang,Z.X., Zeng,Q.Y., Wang,E.D. and Liu,R.J.
  TITLE     A dual role of human tRNA methyltransferase hTrmt13 in regulating
            translation and transcription
  JOURNAL   EMBO J 41 (6), e108544 (2022)
   PUBMED   34850409
  REMARK    GeneRIF: A dual role of human tRNA methyltransferase hTrmt13 in
            regulating translation and transcription.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445928.8.
            
            On Apr 10, 2009 this sequence version replaced NP_061956.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002081.1, BC075811.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000370141.8/ ENSP00000359160.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p21.2"
     Protein         1..481
                     /product="tRNA:m(4)X modification enzyme TRM13 homolog
                     isoform 1"
                     /EC_number="2.1.1.225"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM13
                     homolog; tRNA [Gm4] methyltransferase; coiled-coil
                     domain-containing protein 76; tRNA methyltransferase 13
                     homolog; coiled-coil domain containing 76; tRNA:m(4)X
                     modification enzyme TRM13 homolog"
                     /calculated_mol_wt=54116
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0007744|PubMed:19413330,
                     ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:22223895;
                     propagated from UniProtKB/Swiss-Prot (Q9NUP7.2)"
     Region          17..45
                     /region_name="zf-TRM13_CCCH"
                     /note="CCCH zinc finger in TRM13 protein; pfam11722"
                     /db_xref="CDD:463331"
     Region          56..80
                     /region_name="zf-U11-48K"
                     /note="U11-48K-like CHHC zinc finger; pfam05253"
                     /db_xref="CDD:461603"
     Region          165..469
                     /region_name="TRM13"
                     /note="Methyltransferase TRM13; pfam05206"
                     /db_xref="CDD:398743"
     Region          381..408
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NUP7.2)"
     CDS             1..481
                     /gene="TRMT13"
                     /gene_synonym="CCDC76; hTrmt13"
                     /coded_by="NM_019083.3:7..1452"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS765.1"
                     /db_xref="GeneID:54482"
                     /db_xref="HGNC:HGNC:25502"
ORIGIN      
        1 matsatspha pgfpaegrcg yyvekkkrfc rmvvaagkrf cgehagaaee edarkrilcp
       61 ldpkhtvyed qlakhlkkcn srekpkpdfy iqdinaglrd eteipeqlvp isslseeqle
      121 klikklrkas eglnstlkdh imshpalhda lndpkngdsa tkhlkqqasi lgnienlkll
      181 gprrcfvefg agkgklshwv dialkdaekv hfilvekvtt rfkvdgkhrk knsvferlqi
      241 diqhlclnki pvlreeklpv vgigkhlcgm atdlalrclv etyaasfeer neeplakrik
      301 ndktekeiyt lakegneknv pekwnpvagi vialcchhrc dwrhyvgkey fralglgave
      361 fhyfqrmssw atcgmrktsl etsnsttkrq dnqnddseeh ddggyritdd gadclpglls
      421 veekkkighl ckllidqgri qylqqkgfsp alqyytdplv slenvlltal pnhssspett
      481 a
//
LOCUS       NP_001161444             504 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog B isoform a [Homo
            sapiens].
ACCESSION   NP_001161444
VERSION     NP_001161444.1
DBSOURCE    REFSEQ: accession NM_001167972.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 504)
  AUTHORS   Liu,Y., He,X., Yuan,Y., Li,B., Liu,Z., Li,W., Li,K., Tan,S.,
            Zhu,Q., Tang,Z., Han,F., Wu,Z., Shen,L., Jiang,H., Tang,B., Qiu,J.,
            Hu,Z. and Wang,J.
  TITLE     Association of TRMT2B gene variants with juvenile amyotrophic
            lateral sclerosis
  JOURNAL   Front Med 18 (1), 68-80 (2024)
   PUBMED   37874476
  REMARK    GeneRIF: Association of TRMT2B gene variants with juvenile
            amyotrophic lateral sclerosis.
REFERENCE   2  (residues 1 to 504)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   3  (residues 1 to 504)
  AUTHORS   Dai,W., Li,A., Yu,N.J., Nguyen,T., Leach,R.W., Wuhr,M. and
            Kleiner,R.E.
  TITLE     Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated
            dihydrouridylation
  JOURNAL   Nat Chem Biol 17 (11), 1178-1187 (2021)
   PUBMED   34556860
REFERENCE   4  (residues 1 to 504)
  AUTHORS   Powell,C.A. and Minczuk,M.
  TITLE     TRMT2B is responsible for both tRNA and rRNA m5U-methylation in
            human mitochondria
  JOURNAL   RNA Biol 17 (4), 451-462 (2020)
   PUBMED   31948311
  REMARK    GeneRIF: TRMT2B is responsible for both tRNA and rRNA
            m(5)U-methylation in human mitochondria.
REFERENCE   5  (residues 1 to 504)
  AUTHORS   Carter,J.M., Emmett,W., Mozos,I.R., Kotter,A., Helm,M., Ule,J. and
            Hussain,S.
  TITLE     FICC-Seq: a method for enzyme-specified profiling of
            methyl-5-uridine in cellular RNA
  JOURNAL   Nucleic Acids Res 47 (19), e113 (2019)
   PUBMED   31361898
REFERENCE   6  (residues 1 to 504)
  AUTHORS   Lee,S.Y., Kang,M.G., Park,J.S., Lee,G., Ting,A.Y. and Rhee,H.W.
  TITLE     APEX Fingerprinting Reveals the Subcellular Localization of
            Proteins of Interest
  JOURNAL   Cell Rep 15 (8), 1837-1847 (2016)
   PUBMED   27184847
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX647969.1, BC009437.1 and
            Z97985.16.
            
            Summary: This gene encodes a homolog of the TRM2 gene in S.
            cerevisiae. The yeast gene encodes a tRNA methyltransferase that
            plays a role in tRNA maturation. The yeast protein also has
            endo-exonuclease activity and may be involved in DNA double strand
            break repair. Alternative splicing results in multiple transcripts
            encoding different isoforms. [provided by RefSeq, Nov 2009].
            
            Transcript Variant: This variant (a) differs in the 5' UTR,
            compared to variant 1. Variants 1, 2, and 4 all encode isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX647969.1, BC009437.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.1"
     Protein         1..504
                     /product="tRNA (uracil-5-)-methyltransferase homolog B
                     isoform a"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog; TRM2
                     homolog; tRNA (uracil(54)-C(5))-methyltransferase homolog;
                     TRM2 tRNA methyltransferase 2 homolog B; TRM2 homolog B;
                     rRNA (uracil-5-)-methyltransferase TRMT2B; tRNA
                     (uracil-5-)-methyltransferase homolog B"
                     /calculated_mol_wt=56345
     Region          <94..503
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     CDS             1..504
                     /gene="TRMT2B"
                     /gene_synonym="CXorf34; dJ341D10.3"
                     /coded_by="NM_001167972.2:352..1866"
                     /note="isoform a is encoded by transcript variant 4"
                     /db_xref="CCDS:CCDS14477.1"
                     /db_xref="GeneID:79979"
                     /db_xref="HGNC:HGNC:25748"
                     /db_xref="MIM:301128"
ORIGIN      
        1 maglkrrvpl hslryfismv glfskpgllp wyarnppgws qlflgtvckg dftrviatkc
       61 qkgqksqkkp shlgpldgsw qerladvvtp lwrlsyeeql kvkfaaqkki lqrlesyiqm
      121 lngvsvttav pkserlscll hpiipspvin gyrnkstfsv nrgpdgnpkt vgfylgtwrd
      181 gnvvcvqsnh lknipekhsq vaqyyevflr qsplepclvf heggywrelt vrtnsqghtm
      241 aiitfhpqkl sqeelhvqke ivkeffirgp gaacgltsly fqestmtrcs hqqspyqllf
      301 gepyifeell slkirispda ffqintagae mlyrtvgelt gvnsdtilld iccgtgvigl
      361 slaqhtsrvl gielleqave darwtaafng itnsefhtgq aekilpgllk skedgqsiva
      421 vvnparaglh ykviqairnf raihtlvfvs cklhgestrn vielccppdp akkllgepfv
      481 lqqavpvdlf phtphcelvl lftr
//
LOCUS       NP_775956                247 aa            linear   PRI 18-JUN-2025
DEFINITION  E3 SUMO-protein ligase NSE2 isoform 1 [Homo sapiens].
ACCESSION   NP_775956
VERSION     NP_775956.1
DBSOURCE    REFSEQ: accession NM_173685.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 247)
  AUTHORS   Di Benedetto,C., Oh,J., Choudhery,Z., Shi,W., Valdes,G. and
            Betancur,P.
  TITLE     NSMCE2, a novel super-enhancer-regulated gene, is linked to poor
            prognosis and therapy resistance in breast cancer
  JOURNAL   BMC Cancer 22 (1), 1056 (2022)
   PUBMED   36224576
  REMARK    GeneRIF: NSMCE2, a novel super-enhancer-regulated gene, is linked
            to poor prognosis and therapy resistance in breast cancer.
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 247)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (residues 1 to 247)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (residues 1 to 247)
  AUTHORS   Adamus,M., Lelkes,E., Potesil,D., Ganji,S.R., Kolesar,P.,
            Zabrady,K., Zdrahal,Z. and Palecek,J.J.
  TITLE     Molecular Insights into the Architecture of the Human SMC5/6
            Complex
  JOURNAL   J Mol Biol 432 (13), 3820-3837 (2020)
   PUBMED   32389690
REFERENCE   5  (residues 1 to 247)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 247)
  AUTHORS   Potts,P.R.
  TITLE     The Yin and Yang of the MMS21-SMC5/6 SUMO ligase complex in
            homologous recombination
  JOURNAL   DNA Repair (Amst) 8 (4), 499-506 (2009)
   PUBMED   19217832
  REMARK    Review article
REFERENCE   7  (residues 1 to 247)
  AUTHORS   Taylor,E.M., Copsey,A.C., Hudson,J.J., Vidot,S. and Lehmann,A.R.
  TITLE     Identification of the proteins, including MAGEG1, that make up the
            human SMC5-6 protein complex
  JOURNAL   Mol Cell Biol 28 (4), 1197-1206 (2008)
   PUBMED   18086888
REFERENCE   8  (residues 1 to 247)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   9  (residues 1 to 247)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   10 (residues 1 to 247)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     Human MMS21/NSE2 is a SUMO ligase required for DNA repair
  JOURNAL   Mol Cell Biol 25 (16), 7021-7032 (2005)
   PUBMED   16055714
  REMARK    GeneRIF: the human SMC5/6 complex and the SUMO ligase activity of
            hMMS21 are required for the prevention of DNA damage-induced
            apoptosis by facilitating DNA repair in human cells
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CB217595.1 and BC032797.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes a member of a family of E3 small
            ubiquitin-related modifier (SUMO) ligases that mediates the
            attachment of a SUMO protein to proteins involved in nuclear
            transport, transcription, chromosome segregation and DNA repair.
            The encoded protein is part of the structural maintenance of
            chromosomes (SMC) 5/6 complex which plays a key role genome
            maintenance, facilitating chromosome segregation and suppressing
            mitotic recombination. A knockout of the orthologous mouse gene is
            lethal prior to embryonic day 10.5. Naturally occurring mutations
            in this gene, that abolish the SUMO ligase activity, are associated
            with primordial dwarfism and extreme insulin resistance. [provided
            by RefSeq, Mar 2017].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1). Variants 1-3 encode the same isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC032797.1, SRR1803616.418268.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000287437.8/ ENSP00000287437.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.13"
     Protein         1..247
                     /product="E3 SUMO-protein ligase NSE2 isoform 1"
                     /note="E3 SUMO-protein ligase NSE2; methyl
                     methanesulfonate sensitivity gene 21; NSE2 (MMS21)
                     homolog, SMC5-SMC6 complex SUMO ligase; non-structural
                     maintenance of chromosomes element 2 homolog; zinc finger,
                     MIZ-type containing 7; non-SMC element 2, MMS21 homolog;
                     NSMCE2/PVT1 fusion; PVT1/NSMCE2 fusion; E3 SUMO-protein
                     transferase NSE2"
                     /calculated_mol_wt=27801
     Site            1
                     /site_type="acetylation"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0007744|PubMed:20068231; propagated from
                     UniProtKB/Swiss-Prot (Q96MF7.2)"
     Site            116
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q96MF7.2)"
     Region          167..237
                     /region_name="SPL-RING_NSE2"
                     /note="SPL-RING finger found in E3 SUMO-protein ligase
                     NSE2 and similar proteins; cd16651"
                     /db_xref="CDD:438313"
     CDS             1..247
                     /gene="NSMCE2"
                     /gene_synonym="C8orf36; MMS21; NSE2; ZMIZ7"
                     /coded_by="NM_173685.4:210..953"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS6356.1"
                     /db_xref="GeneID:286053"
                     /db_xref="HGNC:HGNC:26513"
                     /db_xref="MIM:617246"
ORIGIN      
        1 mpgrsssnsg stgfisfsgv esalsslknf qacinsgmdt assvaldlve sqtevsseys
       61 mdkamvefat ldrqlnhyvk avqstinhvk eerpekipdl kllvekkfla lqsknsdadf
      121 qnnekfvqfk qqlkelkkqc glqadreadg tegvdediiv tqsqtnftcp itkeemkkpv
      181 knkvcghtye edaivrmies rqkrkkkayc pqigcshtdi rksdliqdea lrraienhnk
      241 krhrhse
//
LOCUS       NP_001266594             510 aa            linear   VRT 18-JUN-2025
DEFINITION  muscarinic acetylcholine receptor M5b [Oreochromis niloticus].
ACCESSION   NP_001266594 XP_003446316
VERSION     NP_001266594.1
DBSOURCE    REFSEQ: accession NM_001279665.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 510)
  AUTHORS   Seo,J.S., Kim,M.S., Park,E.M., Ahn,S.J., Kim,N.Y., Jung,S.H.,
            Kim,J.W., Lee,H.H. and Chung,J.K.
  TITLE     Cloning and characterization of muscarinic receptor genes from the
            nile tilapia (Oreochromis niloticus)
  JOURNAL   Mol Cells 27 (3), 383-390 (2009)
   PUBMED   19326086
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EU729328.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003446316.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: EU729328.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG15"
                     /linkage_group="LG15"
     Protein         1..510
                     /product="muscarinic acetylcholine receptor M5b"
                     /note="muscarinic receptor 5B subtype; cholinergic
                     receptor muscarinic 5"
                     /calculated_mol_wt=57056
     Region          25..478
                     /region_name="7tmA_mAChR"
                     /note="muscarinic acetylcholine receptor subfamily, member
                     of the class A family of seven-transmembrane G
                     protein-coupled receptors; cd15049"
                     /db_xref="CDD:341322"
     Region          26..52
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:341322"
     Region          59..85
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:341322"
     Region          97..127
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:341322"
     Site            order(104..105,108..109,156,188,191..192,195..196,427,
                     430..431,453,456..457)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:341322"
     Region          139..162
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:341322"
     Region          184..305
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:341322"
     Region          407..437
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:341322"
     Region          446..471
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:341322"
     CDS             1..510
                     /gene="chrm5b"
                     /gene_synonym="chrm5"
                     /coded_by="NM_001279665.1:1..1533"
                     /db_xref="GeneID:100534444"
ORIGIN      
        1 mdasnstfgn tshvspaphs lweaiaiatv saivslitiv gnvlvmlsfk vnsqlktvnn
       61 yyllslafad liigvlsmnl yttyilmgyw slgnlacdlw lavdyvasna svmnllvisf
      121 dryfsitrpl tyrakrtpkr aaimiglawl vsfvlwappi lcwqyfvger tvqmnqcqiq
      181 fltqpvitfg taiaafyipv simtilycri yketqkrtkd laelqgltke hvpxgakpqk
      241 tiirscfhft reprdqsqas wsssnqsnat ktttrsdeaw aktdqitsfn sytsseeeeq
      301 hvsietpqgs fkepgsgetn kxgqvtdyae deyfstpqkk nskkcisyrf klgskgkngn
      361 pmsatssppe aelptknasp ssssttskpm dtalknqitk rkrmvlvkek kaaqtlsail
      421 lafiptwtpy nimvlistfc seciptslwh lgywlcyvns tinpmsyalc nktfqktfhm
      481 lllcqwrkrr rgedklywgg qnpnvnnkmt
//
LOCUS       NP_001337518             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337518
VERSION     NP_001337518.1
DBSOURCE    REFSEQ: accession NM_001350589.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (11), as well as variants 8-10 and
            12-19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074968.269889.1,
                                           SRR14038195.1523423.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350589.2:1241..1933"
                     /note="isoform e is encoded by transcript variant 11"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001298246             979 aa            linear   VRT 18-JUN-2025
DEFINITION  toll-like receptor 21 precursor [Oreochromis niloticus].
ACCESSION   NP_001298246
VERSION     NP_001298246.1
DBSOURCE    REFSEQ: accession NM_001311317.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KJ010824.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KJ010824.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2482243, SAMEA2482244
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..979
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG11"
                     /linkage_group="LG11"
     Protein         1..979
                     /product="toll-like receptor 21 precursor"
                     /EC_number="3.2.2.6"
                     /note="TLR21 receptor protein"
                     /calculated_mol_wt=110203
     sig_peptide     1..23
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2409
     Region          20..447
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          85..108
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          109..132
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          133..156
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          157..182
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          183..206
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          207..229
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          230..253
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          316..677
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          353..385
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          387..409
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          410..433
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          434..457
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          458..481
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          482..505
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          506..530
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          531..557
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          558..584
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          585..608
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          609..632
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          635..658
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          659..680
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          797..943
                     /region_name="TIR"
                     /note="Toll - interleukin 1 - resistance; smart00255"
                     /db_xref="CDD:214587"
     CDS             1..979
                     /gene="tlr21"
                     /coded_by="NM_001311317.1:224..3163"
                     /db_xref="GeneID:100703036"
ORIGIN      
        1 mgnlthqlls vtivlaavql issysfrnci aeadsdgktf ncihrnamni fdivsdlpps
       61 ainltilrtr lthlpnnsfs nladlqhlri dnnslttisq lafqglyqlk tlnmslnkis
      121 elnpslfkdl qnltslfman nalkqlpgdi fssvlkldtl ilrqnslsdf sgiaksvahl
      181 tnlttldlcf nnltslrhsn vslpqsltvl yvcknnlltl gcqpsflsfi nildlsynsr
      241 lptkafdqid lstinylllh stnvtivefl disninashv dfsgtglnnd smlkelcill
      301 kkkvkeknlk nmnlgnngir iltnstlsyc pnitgaldls rnnlndtycl eflrrhvyie
      361 dfkaehnhls flkycktnkm fylkkmenls yrynrilnvd pyafyntpnl rtlqlninsi
      421 afldqhalkg lkkletlrld nnlltdlfsv tfedlvslqi lnlrnnrisv ifkrtffnlk
      481 flntldlggn kithfqqsgl dglkslskly ldgnqlkhid pvlyhafqdt ltvldlqsnq
      541 iryvtethes pfmnlsrltd lkldrqrpng ltvlprtllr glyslkslcl tnnniyhlap
      601 dtfddltdls fltldnccvg vtklepgvfk nlrnlsrlaa enmgiqnfsk evfgnltqlr
      661 slqlnrnamq tlsvdalmgl pmlryldird npvsctcnna plqnytknnt dvqvvylynl
      721 scqhnpklkf hnfdtkvcrg digmylffst saaiflftii plfyvklywk mrysyyvfra
      781 wfseqwsrlh eeeenckyda fisynssdeq wvmdqllpnl egggssfklc lhhrdfelgr
      841 divdnivsav yssrkticvv srnflqsewc sleiqlasyr lfdehrdvll lvflepiser
      901 qlssyhrmrk vmlkktylqw pgsdctnptq aqelfwnqlr raiktgtrle teecsathes
      961 keaedfkeer sdenfylqp
//
LOCUS       NP_060591               1173 aa            linear   PRI 18-JUN-2025
DEFINITION  SMC5-SMC6 complex localization factor protein 2 isoform 1 [Homo
            sapiens].
ACCESSION   NP_060591
VERSION     NP_060591.3
DBSOURCE    REFSEQ: accession NM_018121.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 1173)
  AUTHORS   Zhang,L., Wirth,M., Patra,U., Stroh,J., Isaakidis,K., Rieger,L.,
            Kossatz,S., Milanovic,M., Zang,C., Demel,U., Keiten-Schmitz,J.,
            Wagner,K., Steiger,K., Rad,R., Bassermann,F., Muller,S., Keller,U.
            and Schick,M.
  TITLE     Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs
            the DNA damage response
  JOURNAL   EMBO Mol Med 15 (9), e16431 (2023)
   PUBMED   37485814
  REMARK    GeneRIF: Actionable loss of SLF2 drives B-cell lymphomagenesis and
            impairs the DNA damage response.
REFERENCE   2  (residues 1 to 1173)
  AUTHORS   Oravcova,M., Nie,M., Zilio,N., Maeda,S., Jami-Alahmadi,Y.,
            Lazzerini-Denchi,E., Wohlschlegel,J.A., Ulrich,H.D., Otomo,T. and
            Boddy,M.N.
  TITLE     The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral
            replication centers
  JOURNAL   Elife 11, e79676 (2022)
   PUBMED   36373674
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1173)
  AUTHORS   Grange,L.J., Reynolds,J.J., Ullah,F., Isidor,B., Shearer,R.F.,
            Latypova,X., Baxley,R.M., Oliver,A.W., Ganesh,A., Cooke,S.L.,
            Jhujh,S.S., McNee,G.S., Hollingworth,R., Higgs,M.R., Natsume,T.,
            Khan,T., Martos-Moreno,G.A., Chupp,S., Mathew,C.G., Parry,D.,
            Simpson,M.A., Nahavandi,N., Yuksel,Z., Drasdo,M., Kron,A., Vogt,P.,
            Jonasson,A., Seth,S.A., Gonzaga-Jauregui,C., Brigatti,K.W.,
            Stegmann,A.P.A., Kanemaki,M., Josifova,D., Uchiyama,Y., Oh,Y.,
            Morimoto,A., Osaka,H., Ammous,Z., Argente,J., Matsumoto,N.,
            Stumpel,C.T.R.M., Taylor,A.M.R., Jackson,A.P., Bielinsky,A.K.,
            Mailand,N., Le Caignec,C., Davis,E.E. and Stewart,G.S.
  TITLE     Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes
            and mosaic variegated hyperploidy
  JOURNAL   Nat Commun 13 (1), 6664 (2022)
   PUBMED   36333305
  REMARK    GeneRIF: Pathogenic variants in SLF2 and SMC5 cause segmented
            chromosomes and mosaic variegated hyperploidy.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 1173)
  AUTHORS   Scott,W.A., Dhanji,E.Z., Dyakov,B.J.A., Dreseris,E.S., Asa,J.S.,
            Grange,L.J., Mirceta,M., Pearson,C.E., Stewart,G.S., Gingras,A.C.
            and Campos,E.I.
  TITLE     ATRX proximal protein associations boast roles beyond histone
            deposition
  JOURNAL   PLoS Genet 17 (11), e1009909 (2021)
   PUBMED   34780483
  REMARK    GeneRIF: ATRX proximal protein associations boast roles beyond
            histone deposition.
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 1173)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (residues 1 to 1173)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   7  (residues 1 to 1173)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   8  (residues 1 to 1173)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   9  (residues 1 to 1173)
  AUTHORS   Grupe,A., Li,Y., Rowland,C., Nowotny,P., Hinrichs,A.L., Smemo,S.,
            Kauwe,J.S., Maxwell,T.J., Cherny,S., Doil,L., Tacey,K., van
            Luchene,R., Myers,A., Wavrant-De Vrieze,F., Kaleem,M.,
            Hollingworth,P., Jehu,L., Foy,C., Archer,N., Hamilton,G.,
            Holmans,P., Morris,C.M., Catanese,J., Sninsky,J., White,T.J.,
            Powell,J., Hardy,J., O'Donovan,M., Lovestone,S., Jones,L.,
            Morris,J.C., Thal,L., Owen,M., Williams,J. and Goate,A.
  TITLE     A scan of chromosome 10 identifies a novel locus showing strong
            association with late-onset Alzheimer disease
  JOURNAL   Am J Hum Genet 78 (1), 78-88 (2006)
   PUBMED   16385451
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   10 (residues 1 to 1173)
  AUTHORS   Nikali,K., Saharinen,J. and Peltonen,L.
  TITLE     cDNA cloning, expression profile and genomic structure of a novel
            human transcript on chromosome 10q24, and its analyses as a
            candidate gene for infantile onset spinocerebellar ataxia
  JOURNAL   Gene 299 (1-2), 111-115 (2002)
   PUBMED   12459258
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF460991.1, BC030565.1 and AI282394.1.
            
            On Jul 4, 2007 this sequence version replaced NP_060591.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.180591.1, AF460991.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000238961.9/ ENSP00000238961.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q24.31"
     Protein         1..1173
                     /product="SMC5-SMC6 complex localization factor protein 2
                     isoform 1"
                     /note="protein FAM178A; family with sequence similarity
                     178, member A; smc5/6 localization factor 1; SMC5-SMC6
                     complex localization factor protein 2; SMC5-SMC6 complex
                     localization factor 2"
                     /calculated_mol_wt=131743
     Region          1..109
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          137..149
                     /region_name="APIM motif"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          161..230
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          256..275
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          280..373
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          <335..624
                     /region_name="PTZ00108"
                     /note="DNA topoisomerase 2-like protein; Provisional"
                     /db_xref="CDD:240271"
     Region          394..620
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Site            481
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q8IX21.2)"
     Site            603
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (Q8IX21.2)"
     Site            607
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (Q8IX21.2)"
     Site            614
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          635..1173
                     /region_name="Interaction with SIMC1.
                     /evidence=ECO:0000269|PubMed:36373674"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          635..663
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          657..1031
                     /region_name="CANIN"
                     /note="Coiled-coil and Nse Interacting (CANIN) domain;
                     pfam14816"
                     /db_xref="CDD:464331"
     Region          664..1166
                     /region_name="NSE6-like domain.
                     /evidence=ECO:0000269|PubMed:36373674"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          702..1173
                     /region_name="Required for interaction with SLF1 and
                     RAD18. /evidence=ECO:0000269|PubMed:36333305"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     CDS             1..1173
                     /gene="SLF2"
                     /gene_synonym="ATELS1; C10orf6; FAM178A; hNSE6"
                     /coded_by="NM_018121.4:149..3670"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS7500.1"
                     /db_xref="GeneID:55719"
                     /db_xref="HGNC:HGNC:17814"
                     /db_xref="MIM:610348"
ORIGIN      
        1 mtrrcmparp gfpsspapgs spprchlrpg stahaaagkr tespgdrkqs iidffkpask
       61 qdrhmldspq ksnikyggsr lsitgteqfe rklsspkesk pkrvppeksp iieafmkgvk
      121 ehhedhgihe srrpclslas kylakgtniy vpssyhlpke mkslkkkhrs perrkslfih
      181 ennekndrdr gktnadskkq ttvaeadifn nssrslssrs slsrhhpees plgakfqlsl
      241 asycrerelk rlrkeqmeqr insensfsea sslslkssie rkykprqeqr kqndiipgkn
      301 nlsnvenghl srkrsssdsw eptsagskqn kfpekrkrns vdsdlkstre smipkaresf
      361 lekrpdgphq kekfikhial ktpgdvlrle diskepsdet dgssaglaps nsgnsghhst
      421 rnsdqiqvag tketkmqkph lplsqeksai kkasnlqknk tassttkeke tklpllsrvp
      481 sagsslvpln akncalpvsk kdkerssske csghstestk hkehkaktnk adsnvssgki
      541 sggplrseyg tptksppaal evvpcipspa apsdkapseg essgnsnags salkrklrgd
      601 fdsdeeslgy nldsdeeeet lksleeimal nfnqtpaatg kppalskglr sqssdytghv
      661 hpgtytntle rlvkemedtq rldelqkqlq edirqgrgik spirigeeds tddedgllee
      721 hkeflkkfsv tidaipdhhp geeifnflns gkifnqytld lrdsgfigqs aveklilksg
      781 ktdqiflttq gfltsayhyv qcpvpvlkwl frmmsvhtdc ivsvqilstl meitirndtf
      841 sdspvwpwip slsdvaavff nmgidfrslf plenlqpdfn edylvsetqt tsrgkeseds
      901 sykpifstlp etnilnvvkf lglctsihpe gyqdreimll ilmlfkmsle kqlkqiplvd
      961 fqsllinlmk nirdwntkvp elclginels shphnllwlv qlvpnwtsrg rqlrqclslv
     1021 iisklldekh edvpnasnlq vsvlhrylvq mkpsdllkkm vlkkkaeqpd giiddslhle
     1081 lekqayylty illhlvgevs cshsfssgqr khfvllcgal ekhvkcdire darlfyrtkv
     1141 kdlvarihgk wqeiiqncrp tqgqlhdfwv pds
//
LOCUS       NP_001230699              63 aa            linear   PRI 18-JUN-2025
DEFINITION  SMC5-SMC6 complex localization factor protein 2 isoform 3 [Homo
            sapiens].
ACCESSION   NP_001230699
VERSION     NP_001230699.1
DBSOURCE    REFSEQ: accession NM_001243770.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 63)
  AUTHORS   Zhang,L., Wirth,M., Patra,U., Stroh,J., Isaakidis,K., Rieger,L.,
            Kossatz,S., Milanovic,M., Zang,C., Demel,U., Keiten-Schmitz,J.,
            Wagner,K., Steiger,K., Rad,R., Bassermann,F., Muller,S., Keller,U.
            and Schick,M.
  TITLE     Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs
            the DNA damage response
  JOURNAL   EMBO Mol Med 15 (9), e16431 (2023)
   PUBMED   37485814
  REMARK    GeneRIF: Actionable loss of SLF2 drives B-cell lymphomagenesis and
            impairs the DNA damage response.
REFERENCE   2  (residues 1 to 63)
  AUTHORS   Oravcova,M., Nie,M., Zilio,N., Maeda,S., Jami-Alahmadi,Y.,
            Lazzerini-Denchi,E., Wohlschlegel,J.A., Ulrich,H.D., Otomo,T. and
            Boddy,M.N.
  TITLE     The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral
            replication centers
  JOURNAL   Elife 11, e79676 (2022)
   PUBMED   36373674
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 63)
  AUTHORS   Grange,L.J., Reynolds,J.J., Ullah,F., Isidor,B., Shearer,R.F.,
            Latypova,X., Baxley,R.M., Oliver,A.W., Ganesh,A., Cooke,S.L.,
            Jhujh,S.S., McNee,G.S., Hollingworth,R., Higgs,M.R., Natsume,T.,
            Khan,T., Martos-Moreno,G.A., Chupp,S., Mathew,C.G., Parry,D.,
            Simpson,M.A., Nahavandi,N., Yuksel,Z., Drasdo,M., Kron,A., Vogt,P.,
            Jonasson,A., Seth,S.A., Gonzaga-Jauregui,C., Brigatti,K.W.,
            Stegmann,A.P.A., Kanemaki,M., Josifova,D., Uchiyama,Y., Oh,Y.,
            Morimoto,A., Osaka,H., Ammous,Z., Argente,J., Matsumoto,N.,
            Stumpel,C.T.R.M., Taylor,A.M.R., Jackson,A.P., Bielinsky,A.K.,
            Mailand,N., Le Caignec,C., Davis,E.E. and Stewart,G.S.
  TITLE     Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes
            and mosaic variegated hyperploidy
  JOURNAL   Nat Commun 13 (1), 6664 (2022)
   PUBMED   36333305
  REMARK    GeneRIF: Pathogenic variants in SLF2 and SMC5 cause segmented
            chromosomes and mosaic variegated hyperploidy.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 63)
  AUTHORS   Scott,W.A., Dhanji,E.Z., Dyakov,B.J.A., Dreseris,E.S., Asa,J.S.,
            Grange,L.J., Mirceta,M., Pearson,C.E., Stewart,G.S., Gingras,A.C.
            and Campos,E.I.
  TITLE     ATRX proximal protein associations boast roles beyond histone
            deposition
  JOURNAL   PLoS Genet 17 (11), e1009909 (2021)
   PUBMED   34780483
  REMARK    GeneRIF: ATRX proximal protein associations boast roles beyond
            histone deposition.
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 63)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (residues 1 to 63)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   7  (residues 1 to 63)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   8  (residues 1 to 63)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   9  (residues 1 to 63)
  AUTHORS   Grupe,A., Li,Y., Rowland,C., Nowotny,P., Hinrichs,A.L., Smemo,S.,
            Kauwe,J.S., Maxwell,T.J., Cherny,S., Doil,L., Tacey,K., van
            Luchene,R., Myers,A., Wavrant-De Vrieze,F., Kaleem,M.,
            Hollingworth,P., Jehu,L., Foy,C., Archer,N., Hamilton,G.,
            Holmans,P., Morris,C.M., Catanese,J., Sninsky,J., White,T.J.,
            Powell,J., Hardy,J., O'Donovan,M., Lovestone,S., Jones,L.,
            Morris,J.C., Thal,L., Owen,M., Williams,J. and Goate,A.
  TITLE     A scan of chromosome 10 identifies a novel locus showing strong
            association with late-onset Alzheimer disease
  JOURNAL   Am J Hum Genet 78 (1), 78-88 (2006)
   PUBMED   16385451
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   10 (residues 1 to 63)
  AUTHORS   Nikali,K., Saharinen,J. and Peltonen,L.
  TITLE     cDNA cloning, expression profile and genomic structure of a novel
            human transcript on chromosome 10q24, and its analyses as a
            candidate gene for infantile onset spinocerebellar ataxia
  JOURNAL   Gene 299 (1-2), 111-115 (2002)
   PUBMED   12459258
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF460991.1, BC073832.1 and AA829402.1.
            
            Transcript Variant: This variant (3) is unspliced, lacks a large
            portion of the coding region and differs in the 3' UTR, compared to
            variant 1. The encoded isoform (3) is significantly shorter and has
            a distinct C-terminus, compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR7410570.466696.1,
                                        SRR1163655.673601.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..63
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q24.31"
     Protein         1..63
                     /product="SMC5-SMC6 complex localization factor protein 2
                     isoform 3"
                     /note="protein FAM178A; family with sequence similarity
                     178, member A; smc5/6 localization factor 1; SMC5-SMC6
                     complex localization factor protein 2; SMC5-SMC6 complex
                     localization factor 2"
                     /calculated_mol_wt=6536
     CDS             1..63
                     /gene="SLF2"
                     /gene_synonym="ATELS1; C10orf6; FAM178A; hNSE6"
                     /coded_by="NM_001243770.2:149..340"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS65918.1"
                     /db_xref="GeneID:55719"
                     /db_xref="HGNC:HGNC:17814"
                     /db_xref="MIM:610348"
ORIGIN      
        1 mtrrcmparp gfpsspapgs spprchlrpg stahaaagkr tespgdryra eglrrgrvag
       61 arv
//
LOCUS       NP_001298244             810 aa            linear   VRT 18-JUN-2025
DEFINITION  fibroblast growth factor receptor 1-A precursor [Oreochromis
            niloticus].
ACCESSION   NP_001298244
VERSION     NP_001298244.1
DBSOURCE    REFSEQ: accession NM_001311315.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KC841657.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KC841657.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..810
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG12"
                     /linkage_group="LG12"
     Protein         1..810
                     /product="fibroblast growth factor receptor 1-A precursor"
                     /EC_number="2.7.10.1"
                     /note="fibroblast growth factor receptor 1"
                     /calculated_mol_wt=87606
     sig_peptide     1..27
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=3056
     Region          24..111
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          47..51
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          59..63
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          80..84
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          94..99
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          104..107
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          144..238
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          165..169
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          178..182
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          204..208
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          218..223
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          231..234
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          246..349
                     /region_name="Ig"
                     /note="Immunoglobulin domain; cl11960"
                     /db_xref="CDD:472250"
     Region          264..268
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          277..281
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          315..319
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          329..334
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          342..345
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     Region          452..753
                     /region_name="PTKc_FGFR1"
                     /note="Catalytic domain of the Protein Tyrosine Kinase,
                     Fibroblast Growth Factor Receptor 1; cd05098"
                     /db_xref="CDD:270678"
     Site            order(472..473,475,477,480,500,502,533,549..552,556,611,
                     615..616,618,629,647..651,660,694)
                     /site_type="active"
                     /db_xref="CDD:270678"
     Site            order(472..473,475,477,480,500,502,533,549..552,556,
                     615..616,618,629)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:270678"
     Site            order(611,615,647..651,660,694)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270678"
     Site            628..653
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270678"
     CDS             1..810
                     /gene="fgfr1a"
                     /gene_synonym="FGFR-1"
                     /coded_by="NM_001311315.1:1..2433"
                     /db_xref="GeneID:100698136"
ORIGIN      
        1 mlmrpsillk lalfaqvlrt qcrpanadev svetqaelyt lsiadrldlt ccakdylhav
       61 nwtkdhvavv dgehtrirng qleiesvelt dsglytcttf pnhsiffnvt vhisassedd
      121 ddgeesssee nkllgsqklm amapqwahpv kmekkqhavp asktvkykcq asgnptptlk
      181 wylngkefkr dhriggfkvr dhmwtiimes vvpsdkgnyt cvvenkygsi nhtyqldvve
      241 rsphrpilqa glpanrtvvv gsdvefeckv fsdpqphiqw lkhievngnr tgpdglpyvk
      301 irptagvntt dkemevlqlr nvsfddagey tclagnsigy shhsawltvf eapphyspas
      361 htylevviyc vgfffiaimi aiaiivkirt tsskksdfns qlavhklaks iplrrqvsvd
      421 ssssihsgvm lvrpsrlsss gspmlsgvse celpqdprwe lprdrlvlgk plgegcfgqv
      481 vmgeavgldk ekpnrvtkva vkmlkadate kdlsdlisem emmkiigkhk niinllgact
      541 qdgplyvive yaskgnlrey lrarrppgme ycsnpdqvpv envsikdlvs fayqvargme
      601 ylaslkcihr dlaarnvlvt ddsvmkiadf glardihhid yykkttngrl pvkwmapeal
      661 fdriythqsd vwsfgvllwe iftlggspyp gvpveelfkl lkeghrmdkp stcthelymm
      721 mrdcwhavps qrptfkqlve dldralamts nqeylelsvp ldqyspsypd trsstcssge
      781 dsvfshdaga eeaclpkfpp hsngaaikkr
//
LOCUS       NP_001337521             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337521
VERSION     NP_001337521.1
DBSOURCE    REFSEQ: accession NM_001350592.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (14), as well as variants 8-13 and
            15-19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038196.1430496.1,
                                           SRR1660809.27636.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350592.2:1152..1844"
                     /note="isoform e is encoded by transcript variant 14"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001266682             515 aa            linear   VRT 18-JUN-2025
DEFINITION  lipoprotein lipase precursor [Oreochromis niloticus].
ACCESSION   NP_001266682 XP_003439889
VERSION     NP_001266682.1
DBSOURCE    REFSEQ: accession NM_001279753.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 515)
  AUTHORS   Han,C., Wen,X., Zheng,Q. and Li,H.
  TITLE     Effect of starvation on activities and mRNA expression of
            lipoprotein lipase and hormone-sensitive lipase in tilapia
            (Oreochromis niloticus x O. areus)
  JOURNAL   Fish Physiol Biochem 37 (1), 113-122 (2011)
   PUBMED   20706869
REFERENCE   2  (residues 1 to 515)
  AUTHORS   Huang,Y., Liang,X.F., Wang,L., Li,G.Z., Liu,X.X. and Yao,Y.
  TITLE     [Molecular characterization and evolutional analysis of liportein
            lipase and hepatic lipase gene in Chinese Sturgeon and other six
            freshwater fishes]
  JOURNAL   Dongwuxue Yanjiu 31 (3), 239-249 (2010)
   PUBMED   20672411
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from GU433189.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003439889.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GU433189.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06335335 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..515
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG23"
                     /linkage_group="LG23"
     Protein         1..515
                     /product="lipoprotein lipase precursor"
                     /EC_number="3.1.1.34"
                     /calculated_mol_wt=54359
     sig_peptide     1..34
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=3740
     Region          52..496
                     /region_name="lipo_lipase"
                     /note="lipoprotein lipase; TIGR03230"
                     /db_xref="CDD:132274"
     CDS             1..515
                     /gene="lpla"
                     /gene_synonym="lpl"
                     /coded_by="NM_001279753.1:127..1674"
                     /db_xref="GeneID:100534504"
ORIGIN      
        1 mgkqnicflt awiilgkifa tfssdlesnt tafanetvti dqllnttewl tdytdivskf
       61 slrtadtpdd dmcyivpgrp etikecnfns etqtfvvihg wtvtgmfesw vpklvsalyd
      121 rvptanvivv dwltranqhy ptsaaytklv grdvakfvtw iqnelqlpwd rvhllgyslg
      181 ahvagiagdl tnhkisritg ldpagptfeh adeqstlsrg daqfvdvlht ntrgspdrsi
      241 giqrpvghid iypnggtfqp gcdiqntlmg ialegikglq nmdqlvkcsh ersihlfids
      301 llnieqqsva lrcnskdtfn kgmclscrkn rcnkigynvk kvrtarstrm ylktrgmmpf
      361 kvfhyqvkah ffsqnqqsft eqpmkislyg tngekediaf vlpslnsntt qsflittdtd
      421 igdlmivklr werdafisws nwwgstkfni rklrikcget qskviftakd gefvdltrgg
      481 enavfvkske dnqsrkekla nklktkgslf gqqda
//
LOCUS       NP_001337524             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337524
VERSION     NP_001337524.1
DBSOURCE    REFSEQ: accession NM_001350595.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (17), as well as variants 8-16,
            18, and 19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.205154.1,
                                           SRR1803611.31508.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148093, SAMEA2149876
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350595.2:1220..1912"
                     /note="isoform e is encoded by transcript variant 17"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001161442             504 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog B isoform a [Homo
            sapiens].
ACCESSION   NP_001161442
VERSION     NP_001161442.1
DBSOURCE    REFSEQ: accession NM_001167970.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 504)
  AUTHORS   Liu,Y., He,X., Yuan,Y., Li,B., Liu,Z., Li,W., Li,K., Tan,S.,
            Zhu,Q., Tang,Z., Han,F., Wu,Z., Shen,L., Jiang,H., Tang,B., Qiu,J.,
            Hu,Z. and Wang,J.
  TITLE     Association of TRMT2B gene variants with juvenile amyotrophic
            lateral sclerosis
  JOURNAL   Front Med 18 (1), 68-80 (2024)
   PUBMED   37874476
  REMARK    GeneRIF: Association of TRMT2B gene variants with juvenile
            amyotrophic lateral sclerosis.
REFERENCE   2  (residues 1 to 504)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   3  (residues 1 to 504)
  AUTHORS   Dai,W., Li,A., Yu,N.J., Nguyen,T., Leach,R.W., Wuhr,M. and
            Kleiner,R.E.
  TITLE     Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated
            dihydrouridylation
  JOURNAL   Nat Chem Biol 17 (11), 1178-1187 (2021)
   PUBMED   34556860
REFERENCE   4  (residues 1 to 504)
  AUTHORS   Powell,C.A. and Minczuk,M.
  TITLE     TRMT2B is responsible for both tRNA and rRNA m5U-methylation in
            human mitochondria
  JOURNAL   RNA Biol 17 (4), 451-462 (2020)
   PUBMED   31948311
  REMARK    GeneRIF: TRMT2B is responsible for both tRNA and rRNA
            m(5)U-methylation in human mitochondria.
REFERENCE   5  (residues 1 to 504)
  AUTHORS   Carter,J.M., Emmett,W., Mozos,I.R., Kotter,A., Helm,M., Ule,J. and
            Hussain,S.
  TITLE     FICC-Seq: a method for enzyme-specified profiling of
            methyl-5-uridine in cellular RNA
  JOURNAL   Nucleic Acids Res 47 (19), e113 (2019)
   PUBMED   31361898
REFERENCE   6  (residues 1 to 504)
  AUTHORS   Lee,S.Y., Kang,M.G., Park,J.S., Lee,G., Ting,A.Y. and Rhee,H.W.
  TITLE     APEX Fingerprinting Reveals the Subcellular Localization of
            Proteins of Interest
  JOURNAL   Cell Rep 15 (8), 1837-1847 (2016)
   PUBMED   27184847
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA454040.1, BC020116.1,
            DA391184.1 and Z97985.16.
            
            Summary: This gene encodes a homolog of the TRM2 gene in S.
            cerevisiae. The yeast gene encodes a tRNA methyltransferase that
            plays a role in tRNA maturation. The yeast protein also has
            endo-exonuclease activity and may be involved in DNA double strand
            break repair. Alternative splicing results in multiple transcripts
            encoding different isoforms. [provided by RefSeq, Nov 2009].
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1, 2, and 4 all encode isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC020116.1, SRR1660807.167796.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.1"
     Protein         1..504
                     /product="tRNA (uracil-5-)-methyltransferase homolog B
                     isoform a"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog; TRM2
                     homolog; tRNA (uracil(54)-C(5))-methyltransferase homolog;
                     TRM2 tRNA methyltransferase 2 homolog B; TRM2 homolog B;
                     rRNA (uracil-5-)-methyltransferase TRMT2B; tRNA
                     (uracil-5-)-methyltransferase homolog B"
                     /calculated_mol_wt=56345
     Region          <94..503
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     CDS             1..504
                     /gene="TRMT2B"
                     /gene_synonym="CXorf34; dJ341D10.3"
                     /coded_by="NM_001167970.2:409..1923"
                     /note="isoform a is encoded by transcript variant 2"
                     /db_xref="CCDS:CCDS14477.1"
                     /db_xref="GeneID:79979"
                     /db_xref="HGNC:HGNC:25748"
                     /db_xref="MIM:301128"
ORIGIN      
        1 maglkrrvpl hslryfismv glfskpgllp wyarnppgws qlflgtvckg dftrviatkc
       61 qkgqksqkkp shlgpldgsw qerladvvtp lwrlsyeeql kvkfaaqkki lqrlesyiqm
      121 lngvsvttav pkserlscll hpiipspvin gyrnkstfsv nrgpdgnpkt vgfylgtwrd
      181 gnvvcvqsnh lknipekhsq vaqyyevflr qsplepclvf heggywrelt vrtnsqghtm
      241 aiitfhpqkl sqeelhvqke ivkeffirgp gaacgltsly fqestmtrcs hqqspyqllf
      301 gepyifeell slkirispda ffqintagae mlyrtvgelt gvnsdtilld iccgtgvigl
      361 slaqhtsrvl gielleqave darwtaafng itnsefhtgq aekilpgllk skedgqsiva
      421 vvnparaglh ykviqairnf raihtlvfvs cklhgestrn vielccppdp akkllgepfv
      481 lqqavpvdlf phtphcelvl lftr
//
LOCUS       NP_001317968             643 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog A isoform c [Homo
            sapiens].
ACCESSION   NP_001317968 XP_016884259
VERSION     NP_001317968.1
DBSOURCE    REFSEQ: accession NM_001331039.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 643)
  AUTHORS   Witzenberger,M., Burczyk,S., Settele,D., Mayer,W., Welp,L.M.,
            Heiss,M., Wagner,M., Monecke,T., Janowski,R., Carell,T., Urlaub,H.,
            Hauck,S.M., Voigt,A. and Niessing,D.
  TITLE     Human TRMT2A methylates tRNA and contributes to translation
            fidelity
  JOURNAL   Nucleic Acids Res 51 (16), 8691-8710 (2023)
   PUBMED   37395448
  REMARK    GeneRIF: Human TRMT2A methylates tRNA and contributes to
            translation fidelity.
REFERENCE   2  (residues 1 to 643)
  AUTHORS   Dai,W., Li,A., Yu,N.J., Nguyen,T., Leach,R.W., Wuhr,M. and
            Kleiner,R.E.
  TITLE     Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated
            dihydrouridylation
  JOURNAL   Nat Chem Biol 17 (11), 1178-1187 (2021)
   PUBMED   34556860
REFERENCE   3  (residues 1 to 643)
  AUTHORS   Pereira,M., Ribeiro,D.R., Pinheiro,M.M., Ferreira,M., Kellner,S.
            and Soares,A.R.
  TITLE     m5U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation
            of tRNA-Derived Small RNAs
  JOURNAL   Int J Mol Sci 22 (6), 2941 (2021)
   PUBMED   33799331
  REMARK    GeneRIF: m(5)U54 tRNA Hypomodification by Lack of TRMT2A Drives the
            Generation of tRNA-Derived Small RNAs.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 643)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (residues 1 to 643)
  AUTHORS   Cheng,Q.Y., Xiong,J., Ma,C.J., Dai,Y., Ding,J.H., Liu,F.L.,
            Yuan,B.F. and Feng,Y.Q.
  TITLE     Chemical tagging for sensitive determination of uridine
            modifications in RNA
  JOURNAL   Chem Sci 11 (7), 1878-1891 (2020)
   PUBMED   34123281
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 643)
  AUTHORS   Hicks,D.G., Janarthanan,B.R., Vardarajan,R., Kulkarni,S.A.,
            Khoury,T., Dim,D., Budd,G.T., Yoder,B.J., Tubbs,R., Schreeder,M.T.,
            Estopinal,N.C., Beck,R.A., Wang,Y., Ring,B.Z., Seitz,R.S. and
            Ross,D.T.
  TITLE     The expression of TRMT2A, a novel cell cycle regulated protein,
            identifies a subset of breast cancer patients with HER2
            over-expression that are at an increased risk of recurrence
  JOURNAL   BMC Cancer 10, 108 (2010)
   PUBMED   20307320
  REMARK    GeneRIF: TRMT2A staining showed a strong correlation with
            likelihood of recurrence at five years in 67 HER2+ breast cancer.
            Publication Status: Online-Only
REFERENCE   7  (residues 1 to 643)
  AUTHORS   Liu,Y.L., Fann,C.S., Liu,C.M., Chang,C.C., Yang,W.C., Wu,J.Y.,
            Hung,S.I., Chan,H.Y., Chen,J.J., Hsieh,M.H., Hwang,T.J.,
            Faraone,S.V., Tsuang,M.T., Chen,W.J. and Hwu,H.G.
  TITLE     HTF9C gene of 22q11.21 region associates with schizophrenia having
            deficit-sustained attention
  JOURNAL   Psychiatr Genet 17 (6), 333-338 (2007)
   PUBMED   18075473
  REMARK    GeneRIF: Single nucleotid polymorphisms of this gene may be
            associated with a deficit in sustained attention within
            schizophrenia, in a Taiwanese cohort.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (residues 1 to 643)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
REFERENCE   9  (residues 1 to 643)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
REFERENCE   10 (residues 1 to 643)
  AUTHORS   Di Matteo,G., Salerno,M., Guarguaglini,G., Di Fiore,B., Palitti,F.
            and Lavia,P.
  TITLE     Interactions with single-stranded and double-stranded DNA-binding
            factors and alternative promoter conformation upon transcriptional
            activation of the Htf9-a/RanBP1 and Htf9-c genes
  JOURNAL   J Biol Chem 273 (1), 495-505 (1998)
   PUBMED   9417108
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC006547.9 and CA440188.1.
            
            On Sep 3, 2016 this sequence version replaced XP_016884259.1.
            
            Summary: The protein encoded by this gene is of unknown function.
            However, it is orthologous to the mouse Trmt2a gene and contains an
            RNA methyltransferase domain. Expression of this gene varies during
            the cell cycle, with aberrant expression being a possible biomarker
            in certain breast cancers. Several transcript variants encoding two
            different isoforms have been found for this gene. [provided by
            RefSeq, Apr 2012].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038193.4199665.1,
                                           SRR18074969.1442195.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.21"
     Protein         1..643
                     /product="tRNA (uracil-5-)-methyltransferase homolog A
                     isoform c"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog A; tRNA
                     methyltransferase 2 homolog A; hpaII tiny fragments locus
                     9c protein; TRM2 tRNA methyltransferase 2 homolog A; mRNA
                     (uracil-5-)-methyltransferase TRMT2A"
                     /calculated_mol_wt=70704
     Region          68..146
                     /region_name="RRM_TRMT2A"
                     /note="RNA recognition motif (RRM) found in tRNA
                     (uracil-5-)-methyltransferase homolog A (TRMT2A) and
                     similar proteins; cd12439"
                     /db_xref="CDD:409873"
     Region          <178..605
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     CDS             1..643
                     /gene="TRMT2A"
                     /gene_synonym="HTF9C"
                     /coded_by="NM_001331039.2:321..2252"
                     /note="isoform c is encoded by transcript variant 4"
                     /db_xref="CCDS:CCDS82693.1"
                     /db_xref="GeneID:27037"
                     /db_xref="HGNC:HGNC:24974"
                     /db_xref="MIM:611151"
ORIGIN      
        1 msenldnegp kpmescgqes ssalscptvs vppaapaale evekegagaa tgpgpqpgly
       61 syirddlfts eifklelqnv prhasfsdvr rflgrfglqp hktklfgqpp cafvtfrsaa
      121 erdkalrvlh galwkgrpls vrlarpkadp marrrrqege seppvtrvad vvtplwtvpy
      181 aeqlerkqle ceqvlqklak eigstnrall pwlleqrhkh nkaccplegv rpspqqteyr
      241 nkceflvgvg vdgedntvgc rlgkykggtc avaapfdtvh ipeatkqvvk afqefirstp
      301 ysaydpetyt ghwkqltvrt srrhqamaia yfhpqklspe elaelktsla qhftagpgra
      361 sgvtclyfve egqrktpsqe glplehvagd rcihedllgl tfrisphaff qvntpaaevl
      421 ytviqdwaql dagsmvldvc cgtgtiglal argpmysppw vgrhhaflfq kvkrvigvel
      481 cpeavedarv naqdnelsnv efhcgraedl vptlvsrlas qhlvaildpp raglhskvil
      541 airraknlrr llyvscnpra amgnfvdlcr apsnrvkgip frpvkavavd lfpqtphcem
      601 lilfervehp ngtgvlgphs ppaqptpgpp dntlqetgtf pss
//
LOCUS       NP_001380342             282 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA:m(4)X modification enzyme TRM13 homolog isoform 6 [Homo
            sapiens].
ACCESSION   NP_001380342
VERSION     NP_001380342.1
DBSOURCE    REFSEQ: accession NM_001393413.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 282)
  AUTHORS   Li,H., Dong,H., Xu,B., Xiong,Q.P., Li,C.T., Yang,W.Q., Li,J.,
            Huang,Z.X., Zeng,Q.Y., Wang,E.D. and Liu,R.J.
  TITLE     A dual role of human tRNA methyltransferase hTrmt13 in regulating
            translation and transcription
  JOURNAL   EMBO J 41 (6), e108544 (2022)
   PUBMED   34850409
  REMARK    GeneRIF: A dual role of human tRNA methyltransferase hTrmt13 in
            regulating translation and transcription.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445928.8.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC057226.1, SRR1803613.383873.1
                                           [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p21.2"
     Protein         1..282
                     /product="tRNA:m(4)X modification enzyme TRM13 homolog
                     isoform 6"
                     /EC_number="2.1.1.225"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM13
                     homolog; tRNA [Gm4] methyltransferase; coiled-coil
                     domain-containing protein 76; tRNA methyltransferase 13
                     homolog; coiled-coil domain containing 76; tRNA:m(4)X
                     modification enzyme TRM13 homolog"
                     /calculated_mol_wt=31632
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0007744|PubMed:19413330,
                     ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:22223895;
                     propagated from UniProtKB/Swiss-Prot (Q9NUP7.2)"
     Region          17..45
                     /region_name="zf-TRM13_CCCH"
                     /note="CCCH zinc finger in TRM13 protein; pfam11722"
                     /db_xref="CDD:463331"
     Region          56..80
                     /region_name="zf-U11-48K"
                     /note="U11-48K-like CHHC zinc finger; pfam05253"
                     /db_xref="CDD:461603"
     Region          165..>274
                     /region_name="AdoMet_MTases"
                     /note="S-adenosylmethionine-dependent methyltransferases
                     (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes
                     that use S-adenosyl-L-methionine (SAM or AdoMet) as a
                     substrate for methyltransfer, creating the product
                     S-adenosyl-L-homocysteine (AdoHcy); cl17173"
                     /db_xref="CDD:473071"
     CDS             1..282
                     /gene="TRMT13"
                     /gene_synonym="CCDC76; hTrmt13"
                     /coded_by="NM_001393413.1:7..855"
                     /note="isoform 6 is encoded by transcript variant 6"
                     /db_xref="GeneID:54482"
                     /db_xref="HGNC:HGNC:25502"
ORIGIN      
        1 matsatspha pgfpaegrcg yyvekkkrfc rmvvaagkrf cgehagaaee edarkrilcp
       61 ldpkhtvyed qlakhlkkcn srekpkpdfy iqdinaglrd eteipeqlvp isslseeqle
      121 klikklrkas eglnstlkdh imshpalhda lndpkngdsa tkhlkqqasi lgnienlkll
      181 gprrcfvefg agkgklshwv dialkdaekv hfilvekvtt rfkvdgkhrk knsvferlqi
      241 diqhlclnki pvlreeklpv vgigkhlcgm atgflvlkkr rk
//
LOCUS       NP_001337520             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337520
VERSION     NP_001337520.1
DBSOURCE    REFSEQ: accession NM_001350591.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (13), as well as variants 8-12 and
            14-19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038196.2738451.1,
                                           SRR18074968.3356135.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350591.2:1128..1820"
                     /note="isoform e is encoded by transcript variant 13"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001337525             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337525
VERSION     NP_001337525.1
DBSOURCE    REFSEQ: accession NM_001350596.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (18), as well as variants 8-17 and
            19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074968.1927856.1,
                                           SRR1803616.186339.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350596.2:1279..1971"
                     /note="isoform e is encoded by transcript variant 18"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_060426                448 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA wybutosine-synthesizing protein 2 homolog [Homo sapiens].
ACCESSION   NP_060426
VERSION     NP_060426.2
DBSOURCE    REFSEQ: accession NM_017956.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 448)
  AUTHORS   Rossello-Tortella,M., Llinas-Arias,P., Sakaguchi,Y., Miyauchi,K.,
            Davalos,V., Setien,F., Calleja-Cervantes,M.E., Pineyro,D.,
            Martinez-Gomez,J., Guil,S., Joshi,R., Villanueva,A., Suzuki,T. and
            Esteller,M.
  TITLE     Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces
            ribosome frameshifts in colon cancer
  JOURNAL   Proc Natl Acad Sci U S A 117 (34), 20785-20793 (2020)
   PUBMED   32778592
  REMARK    GeneRIF: Epigenetic loss of the transfer RNA-modifying enzyme TYW2
            induces ribosome frameshifts in colon cancer.
REFERENCE   2  (residues 1 to 448)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (residues 1 to 448)
  AUTHORS   Rodriguez,V., Vasudevan,S., Noma,A., Carlson,B.A., Green,J.E.,
            Suzuki,T. and Chandrasekharappa,S.C.
  TITLE     Structure-function analysis of human TYW2 enzyme required for the
            biosynthesis of a highly modified Wybutosine (yW) base in
            phenylalanine-tRNA
  JOURNAL   PLoS One 7 (6), e39297 (2012)
   PUBMED   22761755
REFERENCE   4  (residues 1 to 448)
  AUTHORS   Rodriguez,V., Chen,Y., Elkahloun,A., Dutra,A., Pak,E. and
            Chandrasekharappa,S.
  TITLE     Chromosome 8 BAC array comparative genomic hybridization and
            expression analysis identify amplification and overexpression of
            TRMT12 in breast cancer
  JOURNAL   Genes Chromosomes Cancer 46 (7), 694-707 (2007)
   PUBMED   17440925
  REMARK    GeneRIF: analysis by RT-qPCR using RNA from 30 breast tumors showed
            TRMT12 was overexpressed >2 fold in 87% of the tumors. TRMT12 is a
            homologue of a yeast gene encoding a tRNA methyltransferase
            involved in the posttranscriptional modification of tRNA(Phe)
REFERENCE   5  (residues 1 to 448)
  AUTHORS   Noma,A. and Suzuki,T.
  TITLE     Ribonucleome analysis identified enzyme genes responsible for
            wybutosine synthesis
  JOURNAL   Nucleic Acids Symp Ser (Oxf) (50), 65-66 (2006)
   PUBMED   17150819
REFERENCE   6  (residues 1 to 448)
  AUTHORS   Kalhor,H.R., Penjwini,M. and Clarke,S.
  TITLE     A novel methyltransferase required for the formation of the
            hypermodified nucleoside wybutosine in eucaryotic tRNA
  JOURNAL   Biochem Biophys Res Commun 334 (2), 433-440 (2005)
   PUBMED   16005430
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP342608.1, AK222727.1 and AA608716.1.
            
            On Sep 20, 2007 this sequence version replaced NP_060426.1.
            
            Summary: Wybutosine (yW) is a hypermodified guanosine at the
            3-prime position adjacent to the anticodon of phenylalanine tRNA
            that stabilizes codon-anticodon interactions during decoding on the
            ribosome. TRMT12 is the human homolog of a yeast gene essential for
            yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK225083.1, SRR1660803.138373.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000328599.4/ ENSP00000329858.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..448
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.13"
     Protein         1..448
                     /product="tRNA wybutosine-synthesizing protein 2 homolog"
                     /EC_number="2.5.1.114"
                     /note="homolog of yeast tRNA methyltransferase;
                     tRNA-yW-synthesizing protein 2;
                     alpha-amino-alpha-carboxypropyl transferase TYW2; tRNA
                     methyltranferase 12 homolog; tRNA methyltransferase 12
                     homolog; tRNA(Phe) (4-demethylwyosine(37)-C(7))
                     aminocarboxypropyltransferase"
                     /calculated_mol_wt=50105
     Region          30..441
                     /region_name="Trm5"
                     /note="tRNA G37 N-methylase Trm5 [Translation, ribosomal
                     structure and biogenesis]; COG2520"
                     /db_xref="CDD:442010"
     CDS             1..448
                     /gene="TYW2"
                     /gene_synonym="TRM12; TRMT12"
                     /coded_by="NM_017956.4:109..1455"
                     /db_xref="CCDS:CCDS6349.1"
                     /db_xref="GeneID:55039"
                     /db_xref="HGNC:HGNC:26091"
                     /db_xref="MIM:611244"
ORIGIN      
        1 mrenvvvsnm eresgkpvav vavvtepwft qryreylqrq klfdtqhrve kmpdgsvalp
       61 vlgetlpeqh lqelrnrvap gspcmltqlp dpvpskraqg cspaqklcle vsrwvegrgv
      121 kwsaeleadl prswqrhgnl lllsedcfqa kqwknlgpel wetvalalgv qrlakrgrvs
      181 pdgtrtpavt lllgdhgwve hvdngirykf dvtqcmfsfg niteklrvas lscagevlvd
      241 lyagigyftl pflvhagaaf vhacewnpha vvalrnnlei ngvadrcqih fgdnrklkls
      301 niadrvilgl ipsseegwpi acqvlrqdag gilhihqnve sfpgknlqal gvskvekehw
      361 lypqqittnq wkngatrdsr gkmlspatkp ewqrwaesae triatllqqv hgkpwktqil
      421 hiqpvksyap hvdhivldle ccpcpsvg
//
LOCUS       NP_001266707             303 aa            linear   VRT 18-JUN-2025
DEFINITION  forkhead box protein L2a [Oreochromis niloticus].
ACCESSION   NP_001266707 XP_003459563
VERSION     NP_001266707.1
DBSOURCE    REFSEQ: accession NM_001279778.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 303)
  AUTHORS   Dai,S., Qi,S., Wei,X., Liu,X., Li,Y., Zhou,X., Xiao,H., Lu,B.,
            Wang,D. and Li,M.
  TITLE     Germline sexual fate is determined by the antagonistic action of
            dmrt1 and foxl3/foxl2 in tilapia
  JOURNAL   Development 148 (8) (2021)
   PUBMED   33741713
  REMARK    GeneRIF: Germline sexual fate is determined by the antagonistic
            action of dmrt1 and foxl3/foxl2 in tilapia.
REFERENCE   2  (residues 1 to 303)
  AUTHORS   Shirak,A., Seroussi,E., Cnaani,A., Howe,A.E., Domokhovsky,R.,
            Zilberman,N., Kocher,T.D., Hulata,G. and Ron,M.
  TITLE     Amh and Dmrta2 genes map to tilapia (Oreochromis spp.) linkage
            group 23 within quantitative trait locus regions for sex
            determination
  JOURNAL   Genetics 174 (3), 1573-1581 (2006)
   PUBMED   16951079
REFERENCE   3  (residues 1 to 303)
  AUTHORS   Wang,D., Kobayashi,T., Zhou,L. and Nagahama,Y.
  TITLE     Molecular cloning and gene expression of Foxl2 in the Nile tilapia,
            Oreochromis niloticus
  JOURNAL   Biochem Biophys Res Commun 320 (1), 83-89 (2004)
   PUBMED   15207705
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY554172.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003459563.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AY554172.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG14"
                     /linkage_group="LG14"
     Protein         1..303
                     /product="forkhead box protein L2a"
                     /note="forkhead transcription factor L2; forkhead box L2"
                     /calculated_mol_wt=34204
     Region          47..135
                     /region_name="FH_FOXL2"
                     /note="Forkhead (FH) domain found in Forkhead box protein
                     L2 (FOXL2) and similar proteins; cd20028"
                     /db_xref="CDD:410802"
     Site            order(52,70..71,74,93..94,96..97,100,107,117..119,121)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:410802"
     CDS             1..303
                     /gene="foxl2a"
                     /gene_synonym="foxl2"
                     /coded_by="NM_001279778.1:209..1120"
                     /db_xref="GeneID:100534517"
ORIGIN      
        1 mmatyqnped damalmihdt nttkekerpk eepvqdkvse kpdpsqkppy syvaliamai
       61 ressekrltl sgiyqyiitk fpfyeknkkg wqnsirhnls lnecfikvpr egggerkgny
      121 wtldpacedm fekgnyrrrr rmkrpfrppp thfqpgkalf ggdsygylsp pkylqssfmn
      181 nswslgqppt pmsytscqma sgnvspvnvk glsapssynp ysrvqsmalp smvnsyngms
      241 hhhhphhtqq lspataappp vsssngaglq facsrqpael smmhcsyweh etkhsalhtr
      301 idi
//
LOCUS       NP_001266406             667 aa            linear   VRT 18-JUN-2025
DEFINITION  estrogen receptor 2b [Oreochromis niloticus].
ACCESSION   NP_001266406 XP_003451222
VERSION     NP_001266406.1
DBSOURCE    REFSEQ: accession NM_001279477.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 667)
  AUTHORS   Yan,L., Feng,H., Wang,F., Lu,B., Liu,X., Sun,L. and Wang,D.
  TITLE     Establishment of three estrogen receptors (esr1, esr2a, esr2b)
            knockout lines for functional study in Nile tilapia
  JOURNAL   J Steroid Biochem Mol Biol 191, 105379 (2019)
   PUBMED   31078694
  REMARK    GeneRIF: This study provides evidence for differential functions of
            estrogen receptors - esr1, esr2a and esr2b in fish reproduction.
REFERENCE   2  (residues 1 to 667)
  AUTHORS   Kitahashi,T., Ogawa,S., Soga,T., Sakuma,Y. and Parhar,I.
  TITLE     Sexual maturation modulates expression of nuclear receptor types in
            laser-captured single cells of the cichlid (Oreochromis niloticus)
            pituitary
  JOURNAL   Endocrinology 148 (12), 5822-5830 (2007)
   PUBMED   17823257
REFERENCE   3  (residues 1 to 667)
  AUTHORS   Wang,D.S., Senthilkumaran,B., Sudhakumari,C.C., Sakai,F.,
            Matsuda,M., Kobayashi,T., Yoshikuni,M. and Nagahama,Y.
  TITLE     Molecular cloning, gene expression and characterization of the
            third estrogen receptor of the Nile tilapia, Oreochromis niloticus
  JOURNAL   Fish Physiol Biochem 31 (2-3), 255-266 (2005)
   PUBMED   20035467
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from DQ462608.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003451222.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ462608.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN07160561 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..667
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG19"
                     /linkage_group="LG19"
     Protein         1..667
                     /product="estrogen receptor 2b"
                     /note="estrogen receptor beta 2; estrogen receptor 2"
                     /calculated_mol_wt=73319
     Region          30..138
                     /region_name="ERbeta_N"
                     /note="Estrogen receptor beta; pfam12497"
                     /db_xref="CDD:463610"
     Region          176..257
                     /region_name="NR_DBD_ER"
                     /note="DNA-binding domain of estrogen receptors (ER) is
                     composed of two C4-type zinc fingers; cd07171"
                     /db_xref="CDD:143545"
     Site            order(181,184,198,201,217,223,233,236)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:143545"
     Site            order(190..193,199..200,202..204,206..207,230..231,234,
                     237)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143545"
     Site            order(216..219,223..224,229,232)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:143545"
     Region          314..550
                     /region_name="NR_LBD_ER"
                     /note="Ligand binding domain of Estrogen receptor, which
                     are activated by the hormone 17beta-estradiol (estrogen);
                     cd06949"
                     /db_xref="CDD:132747"
     Site            order(350,355,357,391,398,525,528)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:132747"
     Site            order(362,366,379..380,384,542,546..547)
                     /site_type="other"
                     /note="coactivator recognition site [polypeptide binding]"
                     /db_xref="CDD:132747"
     Site            order(455,459,461..462,483,487..488,491,505..506,508..510,
                     512..513,516..517,519..520,523)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:132747"
     CDS             1..667
                     /gene="esr2b"
                     /gene_synonym="er-b2; ERbeta; esr2"
                     /coded_by="NM_001279477.1:345..2348"
                     /db_xref="GeneID:100534556"
ORIGIN      
        1 mtsspaldad plpllqleev dsskatervs spgllpamys ppvgidshtv cipspytvsn
       61 hdynhghgpl tfyspsmlsy trppitdsps slcpplspsa fwpshthhsv psltlhctqp
      121 lvynepspha pwldpkvhsi spgssiitcn kllgkksedg aegvkssscs salgkadmhf
      181 cavchdyasg yhygvwsceg ckaffkrsiq ghndyicpat nqctidknrr kscqacrlrk
      241 cyevgmmkcg vrrercgfrg arhrrggpqp rdttgqslvr vglgsrgqrh lhlgtplstl
      301 tpvphtnhth hstmspkefi srimeaeppe iylmedlkkp fteasmmmtl tnladkelvl
      361 miswakkipg fvelsltdqi hllkccwlei lmlglmwrsv dhpgklifsp dfklnrgegq
      421 cvegimeifd mllaatsrfr elklqreeyv clkamillns nlctsspqtp eelesrnkll
      481 rlldsvidal vwaisklgls tqqqtlrlgh ltmllshirh vsnkgmdhls tmkrknvvlv
      541 ydlllemlda niassssqts tsspgsdtss eqqqfpppps hlqpgpdqta taadnttvpp
      601 vevpvldrhl htfqstspsq nlagshldsn dyixaehwsl nngdagpgps aepttyvipd
      661 rvvteta
//
LOCUS       NP_001266694             516 aa            linear   VRT 18-JUN-2025
DEFINITION  steroid 17-alpha-hydroxylase/17,20 lyase [Oreochromis niloticus].
ACCESSION   NP_001266694 XP_003455048
VERSION     NP_001266694.1
DBSOURCE    REFSEQ: accession NM_001279765.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 516)
  AUTHORS   Zhou,L.Y., Wang,D.S., Kobayashi,T., Yano,A., Paul-Prasanth,B.,
            Suzuki,A., Sakai,F. and Nagahama,Y.
  TITLE     A novel type of P450c17 lacking the lyase activity is responsible
            for C21-steroid biosynthesis in the fish ovary and head kidney
  JOURNAL   Endocrinology 148 (9), 4282-4291 (2007)
   PUBMED   17569754
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB292401.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003455048.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB292401.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767858, SAMN00767860
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG13"
                     /linkage_group="LG13"
     Protein         1..516
                     /product="steroid 17-alpha-hydroxylase/17,20 lyase"
                     /note="cytochrome P450 C-17"
                     /calculated_mol_wt=57464
     Region          66..500
                     /region_name="CYP17A1"
                     /note="cytochrome P450 family 17, subfamily A, polypeptide
                     1; cd20673"
                     /db_xref="CDD:410766"
     Site            order(92,102,118..119,127,131,307..308,311..312,315..316,
                     319,375,379,382,443..445,449..453,457)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:410766"
     Site            order(111,119..120,209..210,213..214,217,247,306..307,
                     310..311,314..315,375..376,380,451,491..492)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:410766"
     CDS             1..516
                     /gene="cyp17a1"
                     /gene_synonym="cyp17"
                     /coded_by="NM_001279765.1:54..1604"
                     /db_xref="GeneID:100703469"
ORIGIN      
        1 mawflclcvf mavgltllal qfkfrmsahg sgepphlpal plmgsllslr selpphvlfk
       61 elqvkyghty slmmgshsvi vinqhvhake vllkkgktfa grprtvttdi ltrdgkdiaf
      121 gdysatwkfh rkivhgalcm fgegsasiek ticaeaqslc svlseaadvg laldlapelt
      181 ravtnvicsl cfnssycrgd sefetmlqys qgivdtvakd slvdifpwlq ifpnadlrll
      241 khcvsirdkl lqrkfdehkv nyndhvqrdl idallrakrs aennntseis aesvglsddh
      301 ilmtvgdifg agvettttvl kwaitylihh pevqrriqde ldrtvgdsrs pkltdrgslp
      361 yleatirevl rirpvaplli phvalcdtsi gdftvrkgtr viinlwalhh dekewknper
      421 fdpgrflkse gtgltipsps ylpfgaglrv clgealakme lflflswilq rftlsvppgh
      481 slpslegkfg vvlqtakykv natirpdwar hkcqae
//
LOCUS       NP_001358205             500 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein Helios isoform 2 [Homo sapiens].
ACCESSION   NP_001358205 XP_016859079
VERSION     NP_001358205.1
DBSOURCE    REFSEQ: accession NM_001371276.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 500)
  AUTHORS   Velde,H.M., Vaseghi-Shanjani,M., Smits,J.J., Ramakrishnan,G.,
            Oostrik,J., Wesdorp,M., Astuti,G., Yntema,H.G., Hoefsloot,L.,
            Lanting,C.P., Huynen,M.A., Lehman,A., Turvey,S.E., Pennings,R.J.E.
            and Kremer,H.
  CONSRTM   DOOFNL Consortium
  TITLE     Exome variant prioritization in a large cohort of hearing-impaired
            individuals indicates IKZF2 to be associated with non-syndromic
            hearing loss and guides future research of unsolved cases
  JOURNAL   Hum Genet 143 (11), 1379-1399 (2024)
   PUBMED   39406892
REFERENCE   2  (residues 1 to 500)
  AUTHORS   Lukasik,M., Telec,M., Kazmierski,R., Wojtasz,I.,
            Andrzejewska-Gorczynska,N., Kociemba,W., Dworacki,G., Kozubski,W.P.
            and Frydrychowicz,M.
  TITLE     Temporal changes in regulatory T cell subsets defined by the
            transcription factor Helios in stroke and their potential role in
            stroke-associated infection: a prospective case-control study
  JOURNAL   J Neuroinflammation 20 (1), 275 (2023)
   PUBMED   37996909
  REMARK    GeneRIF: Temporal changes in regulatory T cell subsets defined by
            the transcription factor Helios in stroke and their potential role
            in stroke-associated infection: a prospective case-control study.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 500)
  AUTHORS   Mohajeri,A., Vaseghi-Shanjani,M., Rosenfeld,J.A., Yang,G.X., Lu,H.,
            Sharma,M., Lin,S., Salman,A., Waqas,M., Sababi Azamian,M.,
            Worley,K.C., Del Bel,K.L., Kozak,F.K., Rahmanian,R., Biggs,C.M.,
            Hildebrand,K.J., Lalani,S.R., Nicholas,S.K., Scott,D.A.,
            Mostafavi,S., van Karnebeek,C., Henkelman,E., Halparin,J.,
            Yang,C.L., Armstrong,L., Turvey,S.E. and Lehman,A.
  CONSRTM   Undiagnosed Diseases Network; Care4Rare Canada Consortium
  TITLE     Dominant negative variants in IKZF2 cause ICHAD syndrome, a new
            disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay
  JOURNAL   J Med Genet 60 (11), 1092-1104 (2023)
   PUBMED   37316189
  REMARK    GeneRIF: Dominant negative variants in IKZF2 cause ICHAD syndrome,
            a new disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay.
REFERENCE   4  (residues 1 to 500)
  AUTHORS   Tarighi,M., Shahbazi,M., Saadat,P., Daraei,A., Alizadeh Khatir,A.,
            Rahimifard,K. and Mohammadnia-Afrouzi,M.
  TITLE     Decreased frequency of regulatory T cells and level of helios gene
            expression in secondary progressive multiple sclerosis patients:
            Evidence about the development of multiple sclerosis
  JOURNAL   Int Immunopharmacol 116, 109797 (2023)
   PUBMED   36738680
  REMARK    GeneRIF: Decreased frequency of regulatory T cells and level of
            helios gene expression in secondary progressive multiple sclerosis
            patients: Evidence about the development of multiple sclerosis.
REFERENCE   5  (residues 1 to 500)
  AUTHORS   Zhang,H., Jadhav,R.R., Cao,W., Goronzy,I.N., Zhao,T.V., Jin,J.,
            Ohtsuki,S., Hu,Z., Morales,J., Greenleaf,W.J., Weyand,C.M. and
            Goronzy,J.J.
  TITLE     Aging-associated HELIOS deficiency in naive CD4+ T cells alters
            chromatin remodeling and promotes effector cell responses
  JOURNAL   Nat Immunol 24 (1), 96-109 (2023)
   PUBMED   36510022
  REMARK    GeneRIF: Aging-associated HELIOS deficiency in naive CD4[+] T cells
            alters chromatin remodeling and promotes effector cell responses.
REFERENCE   6  (residues 1 to 500)
  AUTHORS   Nakase,K., Ishimaru,F., Fujii,K., Tabayashi,T., Kozuka,T.,
            Sezaki,N., Matsuo,Y. and Harada,M.
  TITLE     Overexpression of novel short isoforms of Helios in a patient with
            T-cell acute lymphoblastic leukemia
  JOURNAL   Exp Hematol 30 (4), 313-317 (2002)
   PUBMED   11937265
  REMARK    GeneRIF: Novel short isoforms of Helios are overexpressed in a
            patient with T-cell acute lymphoblastic leukemia and may contribute
            to the development of T-cell malignancies. Data for unaltered
            Helios indicates tumor suppressor function.
REFERENCE   7  (residues 1 to 500)
  AUTHORS   Perdomo,J., Holmes,M., Chong,B. and Crossley,M.
  TITLE     Eos and pegasus, two members of the Ikaros family of proteins with
            distinct DNA binding activities
  JOURNAL   J Biol Chem 275 (49), 38347-38354 (2000)
   PUBMED   10978333
REFERENCE   8  (residues 1 to 500)
  AUTHORS   Hosokawa,Y., Maeda,Y. and Seto,M.
  TITLE     Human Helios, an Ikaros-related zinc finger DNA binding protein:
            cDNA cloning and tissue expression pattern
  JOURNAL   Immunogenetics 50 (1-2), 106-108 (1999)
   PUBMED   10541817
REFERENCE   9  (residues 1 to 500)
  AUTHORS   Kelley,C.M., Ikeda,T., Koipally,J., Avitahl,N., Wu,L.,
            Georgopoulos,K. and Morgan,B.A.
  TITLE     Helios, a novel dimerization partner of Ikaros expressed in the
            earliest hematopoietic progenitors
  JOURNAL   Curr Biol 8 (9), 508-515 (1998)
   PUBMED   9560339
REFERENCE   10 (residues 1 to 500)
  AUTHORS   Hahm,K., Cobb,B.S., McCarty,A.S., Brown,K.E., Klug,C.A., Lee,R.,
            Akashi,K., Weissman,I.L., Fisher,A.G. and Smale,S.T.
  TITLE     Helios, a T cell-restricted Ikaros family member that
            quantitatively associates with Ikaros at centromeric
            heterochromatin
  JOURNAL   Genes Dev 12 (6), 782-796 (1998)
   PUBMED   9512513
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC079610.4, AC013736.9 and
            AC108066.3.
            
            On Jul 6, 2019 this sequence version replaced XP_016859079.1.
            
            Summary: This gene encodes a member of the Ikaros family of
            zinc-finger proteins. Three members of this protein family (Ikaros,
            Aiolos and Helios) are hematopoietic-specific transcription factors
            involved in the regulation of lymphocyte development. This protein
            forms homo- or hetero-dimers with other Ikaros family members, and
            is thought to function predominantly in early hematopoietic
            development. Multiple transcript variants encoding different
            isoforms have been found for this gene, but the biological validity
            of some variants has not been determined. [provided by RefSeq, Jul
            2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.239193.1,
                                           SRR14038194.4450520.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..500
                     /product="zinc finger protein Helios isoform 2"
                     /note="zinc finger protein, subfamily 1A, 2 (Helios); zinc
                     finger DNA binding protein Helios; zinc finger protein
                     Helios; ikaros family zinc finger protein 2"
                     /calculated_mol_wt=56635
     Region          107..>181
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          116..136
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(121,123,125,127..128,131..132,135,149,151,155..156,
                     159..160,163,177,179,181,183..184,187..188,192)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          128..153
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          144..164
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          172..193
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..500
                     /gene="IKZF2"
                     /gene_synonym="ANF1A2; HELIOS; ICHAD; IMDIA; ZNF1A2;
                     ZNFN1A2"
                     /coded_by="NM_001371276.1:216..1718"
                     /note="isoform 2 is encoded by transcript variant 5"
                     /db_xref="CCDS:CCDS46507.1"
                     /db_xref="GeneID:22807"
                     /db_xref="HGNC:HGNC:13177"
                     /db_xref="MIM:606234"
ORIGIN      
        1 meteaidgyi tcdnelsper ehsnmaidlt sstpngqhas pshmtstnsv klemqsdeec
       61 drkplsrede irghdegssl eepliessev adnrkvqelq geggirlpng erpfhcnqcg
      121 asftqkgnll rhiklhsgek pfkcpfcsya crrrdaltgh lrthsvgkph kcnycgrsyk
      181 qrssleehke rchnylqnvs meaagqvmsh hvppmedcke qepimdnnis lvpferpavi
      241 ekltgnmgkr ksstpqkfvg eklmrfsypd ihfdmnltye keaelmqshm mdqainnait
      301 ylgaealhpl mqhppstiae vapvissays qvyhpnrier pisretadsh ennmdgpisl
      361 irpksrpqer easpsnscld stdsesshdd hqsyqghpal npkrkqspay mkedvkaldt
      421 tkapkgslkd iykvfngege qirafkcehc rvlfldhvmy tihmgchgyr dplecnicgy
      481 rsqdryefss hivrgehtfh
//
LOCUS       NP_001026882             463 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform a [Homo
            sapiens].
ACCESSION   NP_001026882
VERSION     NP_001026882.2
DBSOURCE    REFSEQ: accession NM_001031712.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 463)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 463)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 463)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 463)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 463)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 463)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 463)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 463)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 463)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 463)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC056878.1 and AF532977.1.
            
            On Apr 28, 2006 this sequence version replaced NP_001026882.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF532977.1, SRR3476690.36675.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000334379.11/ ENSP00000333934.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..463
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform a"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=53290
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0007744|PubMed:22223895,
                     ECO:0007744|PubMed:22814378; propagated from
                     UniProtKB/Swiss-Prot (Q7Z4G4.1)"
     Region          10..332
                     /region_name="TIGR01177"
                     /note="putative methyltransferase, TIGR01177 family"
                     /db_xref="CDD:273486"
     CDS             1..463
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001031712.3:12..1403"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS35496.1"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 malsctlnry lllmaqehle frlpeiksll llfggqfass qetygkspfw ilsipsedia
       61 rnlmkrtvca ksifelwghg qspeelyssl knypvekmvp flhsdstyki kihtfnktlt
      121 qeekikrida leflpfegkv nlkkpqhvfs vledygldpn cipenphniy fgrwiadgqr
      181 eliesysvkk rhfigntsmd aglsfimanh gkvkendivf dpfvgtggll iacahfgayv
      241 ygtdidyntv hglgkatrkn qkwrgpdeni ranlrqygle kyyldvlvsd askpswrkgt
      301 yfdaiitdpp ygirestrrt gsqkeipkgi ekwekcpesh vpvslsyhls dmfldllnfa
      361 aetlvlggrl vywlpvytpe yteemvpwhp clelvsnceq klsshtsrrl itmekvkkfe
      421 nrdqyshlls dhflpyqghn sfrekyfsgv tkriakeeks tqe
//
LOCUS       NP_001266640             191 aa            linear   VRT 18-JUN-2025
DEFINITION  glutathione peroxidase 1a [Oreochromis niloticus].
ACCESSION   NP_001266640 XP_003448383
VERSION     NP_001266640.1
DBSOURCE    REFSEQ: accession NM_001279711.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
REFERENCE   1  (residues 1 to 191)
  AUTHORS   Caxico Vieira,C.A.S., Vieira,J.S., Bastos,M.S., Zancanela,V.,
            Barbosa,L.T., Gasparino,E. and Del Vesco,A.P.
  TITLE     Expression of genes related to antioxidant activity in Nile tilapia
            kept under salinity stress and fed diets containing different
            levels of vitamin C
  JOURNAL   J Toxicol Environ Health A 81 (1-3), 20-30 (2018)
   PUBMED   29173066
  REMARK    GeneRIF: After 24 h, fish raised in 21 per thousand salinity and
            fed with the diet supplemented with vitamin C showed similar GPx
            expression as the control freshwater group.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from GQ853451.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003448383.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GQ853451.1, GR639987.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2482241, SAMEA2482242
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            protein contains selenocysteine :: inferred from conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..191
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG5"
                     /linkage_group="LG5"
     Protein         1..191
                     /product="glutathione peroxidase 1a"
                     /EC_number="1.11.1.9"
                     /calculated_mol_wt=21791
     Region          8..183
                     /region_name="GSH_Peroxidase"
                     /note="Glutathione (GSH) peroxidase family; tetrameric
                     selenoenzymes that catalyze the reduction of a variety of
                     hydroperoxides including lipid peroxidases, using GSH as a
                     specific electron donor substrate. GSH peroxidase contains
                     one selenocysteine residue per...; cd00340"
                     /db_xref="CDD:238207"
     Site            order(40,75,153)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:238207"
     Site            40
                     /site_type="other"
                     /note="Selenocysteine"
     Site            order(74,77,79,82,85,89)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238207"
     CDS             1..191
                     /gene="gpx1a"
                     /coded_by="NM_001279711.1:57..632"
                     /db_xref="GeneID:100534483"
ORIGIN      
        1 maghlkrfyd ltakllsget lrfsalkdkv vlienvaslu gtttrdytqv ndlhsrysae
       61 glvilgvpcn qfghqenckn deilrslkyv rpgngfepkf qllekvdvng kdahplfvyl
      121 keklpfpcdd alglmndpky iiwspvcrnd vswnfekflv gpdgepykry srnfltsdie
      181 adikqllkri k
//
LOCUS       NP_001129595            1186 aa            linear   PRI 18-JUN-2025
DEFINITION  SMC5-SMC6 complex localization factor protein 2 isoform 2 [Homo
            sapiens].
ACCESSION   NP_001129595
VERSION     NP_001129595.1
DBSOURCE    REFSEQ: accession NM_001136123.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 1186)
  AUTHORS   Zhang,L., Wirth,M., Patra,U., Stroh,J., Isaakidis,K., Rieger,L.,
            Kossatz,S., Milanovic,M., Zang,C., Demel,U., Keiten-Schmitz,J.,
            Wagner,K., Steiger,K., Rad,R., Bassermann,F., Muller,S., Keller,U.
            and Schick,M.
  TITLE     Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs
            the DNA damage response
  JOURNAL   EMBO Mol Med 15 (9), e16431 (2023)
   PUBMED   37485814
  REMARK    GeneRIF: Actionable loss of SLF2 drives B-cell lymphomagenesis and
            impairs the DNA damage response.
REFERENCE   2  (residues 1 to 1186)
  AUTHORS   Oravcova,M., Nie,M., Zilio,N., Maeda,S., Jami-Alahmadi,Y.,
            Lazzerini-Denchi,E., Wohlschlegel,J.A., Ulrich,H.D., Otomo,T. and
            Boddy,M.N.
  TITLE     The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral
            replication centers
  JOURNAL   Elife 11, e79676 (2022)
   PUBMED   36373674
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1186)
  AUTHORS   Grange,L.J., Reynolds,J.J., Ullah,F., Isidor,B., Shearer,R.F.,
            Latypova,X., Baxley,R.M., Oliver,A.W., Ganesh,A., Cooke,S.L.,
            Jhujh,S.S., McNee,G.S., Hollingworth,R., Higgs,M.R., Natsume,T.,
            Khan,T., Martos-Moreno,G.A., Chupp,S., Mathew,C.G., Parry,D.,
            Simpson,M.A., Nahavandi,N., Yuksel,Z., Drasdo,M., Kron,A., Vogt,P.,
            Jonasson,A., Seth,S.A., Gonzaga-Jauregui,C., Brigatti,K.W.,
            Stegmann,A.P.A., Kanemaki,M., Josifova,D., Uchiyama,Y., Oh,Y.,
            Morimoto,A., Osaka,H., Ammous,Z., Argente,J., Matsumoto,N.,
            Stumpel,C.T.R.M., Taylor,A.M.R., Jackson,A.P., Bielinsky,A.K.,
            Mailand,N., Le Caignec,C., Davis,E.E. and Stewart,G.S.
  TITLE     Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes
            and mosaic variegated hyperploidy
  JOURNAL   Nat Commun 13 (1), 6664 (2022)
   PUBMED   36333305
  REMARK    GeneRIF: Pathogenic variants in SLF2 and SMC5 cause segmented
            chromosomes and mosaic variegated hyperploidy.
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 1186)
  AUTHORS   Scott,W.A., Dhanji,E.Z., Dyakov,B.J.A., Dreseris,E.S., Asa,J.S.,
            Grange,L.J., Mirceta,M., Pearson,C.E., Stewart,G.S., Gingras,A.C.
            and Campos,E.I.
  TITLE     ATRX proximal protein associations boast roles beyond histone
            deposition
  JOURNAL   PLoS Genet 17 (11), e1009909 (2021)
   PUBMED   34780483
  REMARK    GeneRIF: ATRX proximal protein associations boast roles beyond
            histone deposition.
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 1186)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (residues 1 to 1186)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   7  (residues 1 to 1186)
  AUTHORS   Potts,P.R. and Yu,H.
  TITLE     The SMC5/6 complex maintains telomere length in ALT cancer cells
            through SUMOylation of telomere-binding proteins
  JOURNAL   Nat Struct Mol Biol 14 (7), 581-590 (2007)
   PUBMED   17589526
REFERENCE   8  (residues 1 to 1186)
  AUTHORS   Potts,P.R., Porteus,M.H. and Yu,H.
  TITLE     Human SMC5/6 complex promotes sister chromatid homologous
            recombination by recruiting the SMC1/3 cohesin complex to
            double-strand breaks
  JOURNAL   EMBO J 25 (14), 3377-3388 (2006)
   PUBMED   16810316
REFERENCE   9  (residues 1 to 1186)
  AUTHORS   Grupe,A., Li,Y., Rowland,C., Nowotny,P., Hinrichs,A.L., Smemo,S.,
            Kauwe,J.S., Maxwell,T.J., Cherny,S., Doil,L., Tacey,K., van
            Luchene,R., Myers,A., Wavrant-De Vrieze,F., Kaleem,M.,
            Hollingworth,P., Jehu,L., Foy,C., Archer,N., Hamilton,G.,
            Holmans,P., Morris,C.M., Catanese,J., Sninsky,J., White,T.J.,
            Powell,J., Hardy,J., O'Donovan,M., Lovestone,S., Jones,L.,
            Morris,J.C., Thal,L., Owen,M., Williams,J. and Goate,A.
  TITLE     A scan of chromosome 10 identifies a novel locus showing strong
            association with late-onset Alzheimer disease
  JOURNAL   Am J Hum Genet 78 (1), 78-88 (2006)
   PUBMED   16385451
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   10 (residues 1 to 1186)
  AUTHORS   Nikali,K., Saharinen,J. and Peltonen,L.
  TITLE     cDNA cloning, expression profile and genomic structure of a novel
            human transcript on chromosome 10q24, and its analyses as a
            candidate gene for infantile onset spinocerebellar ataxia
  JOURNAL   Gene 299 (1-2), 111-115 (2002)
   PUBMED   12459258
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF460992.1 and BC030565.1.
            
            Transcript Variant: This variant (2) lacks an exon and differs in
            the 3' UTR, compared to variant 1. The encoded isoform (2) is
            longer and has a distinct C-terminus, compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853559.4800.1, BC030565.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1186
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q24.31"
     Protein         1..1186
                     /product="SMC5-SMC6 complex localization factor protein 2
                     isoform 2"
                     /note="protein FAM178A; family with sequence similarity
                     178, member A; smc5/6 localization factor 1; SMC5-SMC6
                     complex localization factor protein 2; SMC5-SMC6 complex
                     localization factor 2"
                     /calculated_mol_wt=133245
     Region          1..109
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          137..149
                     /region_name="APIM motif"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          161..230
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          256..275
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          280..373
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          <335..624
                     /region_name="PTZ00108"
                     /note="DNA topoisomerase 2-like protein; Provisional"
                     /db_xref="CDD:240271"
     Region          394..620
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Site            481
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (Q8IX21.2)"
     Site            603
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (Q8IX21.2)"
     Site            607
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (Q8IX21.2)"
     Site            614
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          635..663
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8IX21.2)"
     Region          657..1031
                     /region_name="CANIN"
                     /note="Coiled-coil and Nse Interacting (CANIN) domain;
                     pfam14816"
                     /db_xref="CDD:464331"
     CDS             1..1186
                     /gene="SLF2"
                     /gene_synonym="ATELS1; C10orf6; FAM178A; hNSE6"
                     /coded_by="NM_001136123.2:149..3709"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="CCDS:CCDS44470.1"
                     /db_xref="GeneID:55719"
                     /db_xref="HGNC:HGNC:17814"
                     /db_xref="MIM:610348"
ORIGIN      
        1 mtrrcmparp gfpsspapgs spprchlrpg stahaaagkr tespgdrkqs iidffkpask
       61 qdrhmldspq ksnikyggsr lsitgteqfe rklsspkesk pkrvppeksp iieafmkgvk
      121 ehhedhgihe srrpclslas kylakgtniy vpssyhlpke mkslkkkhrs perrkslfih
      181 ennekndrdr gktnadskkq ttvaeadifn nssrslssrs slsrhhpees plgakfqlsl
      241 asycrerelk rlrkeqmeqr insensfsea sslslkssie rkykprqeqr kqndiipgkn
      301 nlsnvenghl srkrsssdsw eptsagskqn kfpekrkrns vdsdlkstre smipkaresf
      361 lekrpdgphq kekfikhial ktpgdvlrle diskepsdet dgssaglaps nsgnsghhst
      421 rnsdqiqvag tketkmqkph lplsqeksai kkasnlqknk tassttkeke tklpllsrvp
      481 sagsslvpln akncalpvsk kdkerssske csghstestk hkehkaktnk adsnvssgki
      541 sggplrseyg tptksppaal evvpcipspa apsdkapseg essgnsnags salkrklrgd
      601 fdsdeeslgy nldsdeeeet lksleeimal nfnqtpaatg kppalskglr sqssdytghv
      661 hpgtytntle rlvkemedtq rldelqkqlq edirqgrgik spirigeeds tddedgllee
      721 hkeflkkfsv tidaipdhhp geeifnflns gkifnqytld lrdsgfigqs aveklilksg
      781 ktdqiflttq gfltsayhyv qcpvpvlkwl frmmsvhtdc ivsvqilstl meitirndtf
      841 sdspvwpwip slsdvaavff nmgidfrslf plenlqpdfn edylvsetqt tsrgkeseds
      901 sykpifstlp etnilnvvkf lglctsihpe gyqdreimll ilmlfkmsle kqlkqiplvd
      961 fqsllinlmk nirdwntkvp elclginels shphnllwlv qlvpnwtsrg rqlrqclslv
     1021 iisklldekh edvpnasnlq vsvlhrylvq mkpsdllkkm vlkkkaeqpd giiddslhle
     1081 lekqayylty illhlvgevs cshsfssgqr khfvllcgal ekhvkcdire darlfyrtkv
     1141 kdlvarihgk wqeiiqncrp tqvsfcytis cilnsfaewh ssyclk
//
LOCUS       NP_001428470             249 aa            linear   VRT 18-JUN-2025
DEFINITION  trypsin-like serine protease domain-containing protein precursor
            [Danio rerio].
ACCESSION   NP_001428470 XP_021329145
VERSION     NP_001428470.1
DBSOURCE    REFSEQ: accession NM_001441541.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 249)
  AUTHORS   Bayes,A., Collins,M.O., Reig-Viader,R., Gou,G., Goulding,D.,
            Izquierdo,A., Choudhary,J.S., Emes,R.D. and Grant,S.G.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 249)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000022.1.
            
            On Jun 13, 2025 this sequence version replaced XP_021329145.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GFIL01037095.1, GDQQ01001875.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476786, SAMEA708836
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..249
                     /organism="Danio rerio"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="22"
                     /map="22"
     Protein         1..249
                     /product="trypsin-like serine protease domain-containing
                     protein precursor"
                     /note="trypsin-like serine protease domain-containing
                     protein"
                     /calculated_mol_wt=25431
     sig_peptide     1..19
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2112
     CDS             1..249
                     /gene="si:dkey-21e2.10"
                     /coded_by="NM_001441541.1:157..906"
                     /db_xref="GeneID:556860"
                     /db_xref="ZFIN:ZDB-GENE-050208-778"
ORIGIN      
        1 mtiisllllv slvphltfta rvgiqdgtea kphsrpymvs lqfyklhmcg gsliteefvl
       61 taahcweedd vltvvtgahd lrkkainnvy kvksyiphpd fnsktlendi mllqlktkvr
      121 lsnnvglisl pkdgedvkad tlcsvagwgd lwskgpetdr lreaetvivn naecerrwes
      181 dyvaskmicv yghggtcsgd sggplvcgdt vvgitsfgep ylcnsrlfpd vhtrisaylp
      241 wihnitgkv
//
LOCUS       NP_001337517             230 aa            linear   PRI 18-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform e [Homo
            sapiens].
ACCESSION   NP_001337517
VERSION     NP_001337517.1
DBSOURCE    REFSEQ: accession NM_001350588.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 230)
  AUTHORS   Wang,C., Ulryck,N., Herzel,L., Pythoud,N., Kleiber,N.,
            Guerineau,V., Jactel,V., Moritz,C., Bohnsack,M.T., Carapito,C.,
            Touboul,D., Bohnsack,K.E. and Graille,M.
  TITLE     N 2-methylguanosine modifications on human tRNAs and snRNA U6 are
            important for cell proliferation, protein translation and pre-mRNA
            splicing
  JOURNAL   Nucleic Acids Res 51 (14), 7496-7519 (2023)
   PUBMED   37283053
  REMARK    Erratum:[Nucleic Acids Res. 2024 Jul 22;52(13):8033. doi:
            10.1093/nar/gkae524. PMID: 38888115]
REFERENCE   2  (residues 1 to 230)
  AUTHORS   Brumele,B., Mutso,M., Telanne,L., Ounap,K., Spunde,K., Abroi,A. and
            Kurg,R.
  TITLE     Human TRMT112-Methyltransferase Network Consists of Seven Partners
            Interacting with a Common Co-Factor
  JOURNAL   Int J Mol Sci 22 (24), 13593 (2021)
   PUBMED   34948388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 230)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   4  (residues 1 to 230)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (residues 1 to 230)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (residues 1 to 230)
  AUTHORS   Kohli,M., Riska,S.M., Mahoney,D.W., Chai,H.S., Hillman,D.W.,
            Rider,D.N., Costello,B.A., Qin,R., Lamba,J., Sahasrabudhe,D.M. and
            Cerhan,J.R.
  TITLE     Germline predictors of androgen deprivation therapy response in
            advanced prostate cancer
  JOURNAL   Mayo Clin Proc 87 (3), 240-246 (2012)
   PUBMED   22386179
  REMARK    GeneRIF: SNPs associated with androgen deprivation failure in
            advanced prostate cancer
REFERENCE   7  (residues 1 to 230)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   8  (residues 1 to 230)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
REFERENCE   9  (residues 1 to 230)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
REFERENCE   10 (residues 1 to 230)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035689.26.
            
            Transcript Variant: This variant (10), as well as variants 8, 9,
            and 11-19, encodes isoform e.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074968.4147304.1,
                                           SRR14038195.1283579.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968189
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q22.32"
     Protein         1..230
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform e"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=26782
     Region          <38..153
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..230
                     /gene="TRMT11"
                     /gene_synonym="C6orf75; MDS024; TRM11; TRMT11-1"
                     /coded_by="NM_001350588.2:1190..1882"
                     /note="isoform e is encoded by transcript variant 10"
                     /db_xref="GeneID:60487"
                     /db_xref="HGNC:HGNC:21080"
ORIGIN      
        1 mtenkntlfn tfslpfsfps gkatrknqkw rgpdeniran lrqyglekyy ldvlvsdask
       61 pswrkgtyfd aiitdppygi restrrtgsq keipkgiekw ekcpeshvpv slsyhlsdmf
      121 ldllnfaaet lvlggrlvyw lpvytpeyte emvpwhpcle lvsnceqkls shtsrrlitm
      181 ekvkkfenrd qyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekstqe
//
LOCUS       NP_001358204             500 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein Helios isoform 2 [Homo sapiens].
ACCESSION   NP_001358204 XP_016859078
VERSION     NP_001358204.1
DBSOURCE    REFSEQ: accession NM_001371275.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 500)
  AUTHORS   Velde,H.M., Vaseghi-Shanjani,M., Smits,J.J., Ramakrishnan,G.,
            Oostrik,J., Wesdorp,M., Astuti,G., Yntema,H.G., Hoefsloot,L.,
            Lanting,C.P., Huynen,M.A., Lehman,A., Turvey,S.E., Pennings,R.J.E.
            and Kremer,H.
  CONSRTM   DOOFNL Consortium
  TITLE     Exome variant prioritization in a large cohort of hearing-impaired
            individuals indicates IKZF2 to be associated with non-syndromic
            hearing loss and guides future research of unsolved cases
  JOURNAL   Hum Genet 143 (11), 1379-1399 (2024)
   PUBMED   39406892
REFERENCE   2  (residues 1 to 500)
  AUTHORS   Lukasik,M., Telec,M., Kazmierski,R., Wojtasz,I.,
            Andrzejewska-Gorczynska,N., Kociemba,W., Dworacki,G., Kozubski,W.P.
            and Frydrychowicz,M.
  TITLE     Temporal changes in regulatory T cell subsets defined by the
            transcription factor Helios in stroke and their potential role in
            stroke-associated infection: a prospective case-control study
  JOURNAL   J Neuroinflammation 20 (1), 275 (2023)
   PUBMED   37996909
  REMARK    GeneRIF: Temporal changes in regulatory T cell subsets defined by
            the transcription factor Helios in stroke and their potential role
            in stroke-associated infection: a prospective case-control study.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 500)
  AUTHORS   Mohajeri,A., Vaseghi-Shanjani,M., Rosenfeld,J.A., Yang,G.X., Lu,H.,
            Sharma,M., Lin,S., Salman,A., Waqas,M., Sababi Azamian,M.,
            Worley,K.C., Del Bel,K.L., Kozak,F.K., Rahmanian,R., Biggs,C.M.,
            Hildebrand,K.J., Lalani,S.R., Nicholas,S.K., Scott,D.A.,
            Mostafavi,S., van Karnebeek,C., Henkelman,E., Halparin,J.,
            Yang,C.L., Armstrong,L., Turvey,S.E. and Lehman,A.
  CONSRTM   Undiagnosed Diseases Network; Care4Rare Canada Consortium
  TITLE     Dominant negative variants in IKZF2 cause ICHAD syndrome, a new
            disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay
  JOURNAL   J Med Genet 60 (11), 1092-1104 (2023)
   PUBMED   37316189
  REMARK    GeneRIF: Dominant negative variants in IKZF2 cause ICHAD syndrome,
            a new disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay.
REFERENCE   4  (residues 1 to 500)
  AUTHORS   Tarighi,M., Shahbazi,M., Saadat,P., Daraei,A., Alizadeh Khatir,A.,
            Rahimifard,K. and Mohammadnia-Afrouzi,M.
  TITLE     Decreased frequency of regulatory T cells and level of helios gene
            expression in secondary progressive multiple sclerosis patients:
            Evidence about the development of multiple sclerosis
  JOURNAL   Int Immunopharmacol 116, 109797 (2023)
   PUBMED   36738680
  REMARK    GeneRIF: Decreased frequency of regulatory T cells and level of
            helios gene expression in secondary progressive multiple sclerosis
            patients: Evidence about the development of multiple sclerosis.
REFERENCE   5  (residues 1 to 500)
  AUTHORS   Zhang,H., Jadhav,R.R., Cao,W., Goronzy,I.N., Zhao,T.V., Jin,J.,
            Ohtsuki,S., Hu,Z., Morales,J., Greenleaf,W.J., Weyand,C.M. and
            Goronzy,J.J.
  TITLE     Aging-associated HELIOS deficiency in naive CD4+ T cells alters
            chromatin remodeling and promotes effector cell responses
  JOURNAL   Nat Immunol 24 (1), 96-109 (2023)
   PUBMED   36510022
  REMARK    GeneRIF: Aging-associated HELIOS deficiency in naive CD4[+] T cells
            alters chromatin remodeling and promotes effector cell responses.
REFERENCE   6  (residues 1 to 500)
  AUTHORS   Nakase,K., Ishimaru,F., Fujii,K., Tabayashi,T., Kozuka,T.,
            Sezaki,N., Matsuo,Y. and Harada,M.
  TITLE     Overexpression of novel short isoforms of Helios in a patient with
            T-cell acute lymphoblastic leukemia
  JOURNAL   Exp Hematol 30 (4), 313-317 (2002)
   PUBMED   11937265
  REMARK    GeneRIF: Novel short isoforms of Helios are overexpressed in a
            patient with T-cell acute lymphoblastic leukemia and may contribute
            to the development of T-cell malignancies. Data for unaltered
            Helios indicates tumor suppressor function.
REFERENCE   7  (residues 1 to 500)
  AUTHORS   Perdomo,J., Holmes,M., Chong,B. and Crossley,M.
  TITLE     Eos and pegasus, two members of the Ikaros family of proteins with
            distinct DNA binding activities
  JOURNAL   J Biol Chem 275 (49), 38347-38354 (2000)
   PUBMED   10978333
REFERENCE   8  (residues 1 to 500)
  AUTHORS   Hosokawa,Y., Maeda,Y. and Seto,M.
  TITLE     Human Helios, an Ikaros-related zinc finger DNA binding protein:
            cDNA cloning and tissue expression pattern
  JOURNAL   Immunogenetics 50 (1-2), 106-108 (1999)
   PUBMED   10541817
REFERENCE   9  (residues 1 to 500)
  AUTHORS   Kelley,C.M., Ikeda,T., Koipally,J., Avitahl,N., Wu,L.,
            Georgopoulos,K. and Morgan,B.A.
  TITLE     Helios, a novel dimerization partner of Ikaros expressed in the
            earliest hematopoietic progenitors
  JOURNAL   Curr Biol 8 (9), 508-515 (1998)
   PUBMED   9560339
REFERENCE   10 (residues 1 to 500)
  AUTHORS   Hahm,K., Cobb,B.S., McCarty,A.S., Brown,K.E., Klug,C.A., Lee,R.,
            Akashi,K., Weissman,I.L., Fisher,A.G. and Smale,S.T.
  TITLE     Helios, a T cell-restricted Ikaros family member that
            quantitatively associates with Ikaros at centromeric
            heterochromatin
  JOURNAL   Genes Dev 12 (6), 782-796 (1998)
   PUBMED   9512513
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC079610.4, AC013736.9 and
            AC108066.3.
            
            On Jul 6, 2019 this sequence version replaced XP_016859078.1.
            
            Summary: This gene encodes a member of the Ikaros family of
            zinc-finger proteins. Three members of this protein family (Ikaros,
            Aiolos and Helios) are hematopoietic-specific transcription factors
            involved in the regulation of lymphocyte development. This protein
            forms homo- or hetero-dimers with other Ikaros family members, and
            is thought to function predominantly in early hematopoietic
            development. Multiple transcript variants encoding different
            isoforms have been found for this gene, but the biological validity
            of some variants has not been determined. [provided by RefSeq, Jul
            2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.1512945.1,
                                           SRR14038193.2531153.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..500
                     /product="zinc finger protein Helios isoform 2"
                     /note="zinc finger protein, subfamily 1A, 2 (Helios); zinc
                     finger DNA binding protein Helios; zinc finger protein
                     Helios; ikaros family zinc finger protein 2"
                     /calculated_mol_wt=56635
     Region          107..>181
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          116..136
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(121,123,125,127..128,131..132,135,149,151,155..156,
                     159..160,163,177,179,181,183..184,187..188,192)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          128..153
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          144..164
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          172..193
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..500
                     /gene="IKZF2"
                     /gene_synonym="ANF1A2; HELIOS; ICHAD; IMDIA; ZNF1A2;
                     ZNFN1A2"
                     /coded_by="NM_001371275.1:310..1812"
                     /note="isoform 2 is encoded by transcript variant 4"
                     /db_xref="CCDS:CCDS46507.1"
                     /db_xref="GeneID:22807"
                     /db_xref="HGNC:HGNC:13177"
                     /db_xref="MIM:606234"
ORIGIN      
        1 meteaidgyi tcdnelsper ehsnmaidlt sstpngqhas pshmtstnsv klemqsdeec
       61 drkplsrede irghdegssl eepliessev adnrkvqelq geggirlpng erpfhcnqcg
      121 asftqkgnll rhiklhsgek pfkcpfcsya crrrdaltgh lrthsvgkph kcnycgrsyk
      181 qrssleehke rchnylqnvs meaagqvmsh hvppmedcke qepimdnnis lvpferpavi
      241 ekltgnmgkr ksstpqkfvg eklmrfsypd ihfdmnltye keaelmqshm mdqainnait
      301 ylgaealhpl mqhppstiae vapvissays qvyhpnrier pisretadsh ennmdgpisl
      361 irpksrpqer easpsnscld stdsesshdd hqsyqghpal npkrkqspay mkedvkaldt
      421 tkapkgslkd iykvfngege qirafkcehc rvlfldhvmy tihmgchgyr dplecnicgy
      481 rsqdryefss hivrgehtfh
//
LOCUS       NP_001266402             443 aa            linear   VRT 18-JUN-2025
DEFINITION  doublesex- and mab-3-related transcription factor 2b [Oreochromis
            niloticus].
ACCESSION   NP_001266402 XP_003452379
VERSION     NP_001266402.1
DBSOURCE    REFSEQ: accession NM_001279473.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY198325.2.
            
            On Jul 22, 2013 this sequence version replaced XP_003452379.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY198325.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00767854, SAMN00767863
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG17"
                     /linkage_group="LG17"
     Protein         1..443
                     /product="doublesex- and mab-3-related transcription
                     factor 2b"
                     /note="DM-related transcriptional factor Dmrt2b"
                     /calculated_mol_wt=49146
     Region          63..109
                     /region_name="DM"
                     /note="DM DNA binding domain; pfam00751"
                     /db_xref="CDD:459924"
     CDS             1..443
                     /gene="dmrt2b"
                     /coded_by="NM_001279473.1:526..1857"
                     /db_xref="GeneID:100534554"
ORIGIN      
        1 msaqlggglq pettvkleel kseevfdvts ppgcprdgge nkvvlfpegq qqqpqmkprk
       61 mtrspkcarc rnhgvvsclk ghkrfcrwrd crcaccllvv erqrvmaaqv alrrqqaaev
      121 rraqgqgkkg vrcaaplrrt ayqcytraae ssivaksilq gikpavpped dtpcwskqtq
      181 rdqthfmcps isarmrkrra fadkelenvm lehelrqrel qndlfppsal lpmlhppplp
      241 ispglhccpp skdpttegqs syvplckykp fyecdfqlyq ffplksryst gndyndfllc
      301 qssqqsrqek evqngwkdse ktkqaevips tsiqrlrndg kamscaipvk spskraeimd
      361 sngsstvtla isasdqgvlg qpdisapsrt fdprpltaks wssdtpadqa aphadsvksp
      421 hggsirtpav rplpfsveal lra
//
LOCUS       NP_001358206             451 aa            linear   PRI 18-JUN-2025
DEFINITION  zinc finger protein Helios isoform 3 [Homo sapiens].
ACCESSION   NP_001358206
VERSION     NP_001358206.1
DBSOURCE    REFSEQ: accession NM_001371277.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 451)
  AUTHORS   Velde,H.M., Vaseghi-Shanjani,M., Smits,J.J., Ramakrishnan,G.,
            Oostrik,J., Wesdorp,M., Astuti,G., Yntema,H.G., Hoefsloot,L.,
            Lanting,C.P., Huynen,M.A., Lehman,A., Turvey,S.E., Pennings,R.J.E.
            and Kremer,H.
  CONSRTM   DOOFNL Consortium
  TITLE     Exome variant prioritization in a large cohort of hearing-impaired
            individuals indicates IKZF2 to be associated with non-syndromic
            hearing loss and guides future research of unsolved cases
  JOURNAL   Hum Genet 143 (11), 1379-1399 (2024)
   PUBMED   39406892
REFERENCE   2  (residues 1 to 451)
  AUTHORS   Lukasik,M., Telec,M., Kazmierski,R., Wojtasz,I.,
            Andrzejewska-Gorczynska,N., Kociemba,W., Dworacki,G., Kozubski,W.P.
            and Frydrychowicz,M.
  TITLE     Temporal changes in regulatory T cell subsets defined by the
            transcription factor Helios in stroke and their potential role in
            stroke-associated infection: a prospective case-control study
  JOURNAL   J Neuroinflammation 20 (1), 275 (2023)
   PUBMED   37996909
  REMARK    GeneRIF: Temporal changes in regulatory T cell subsets defined by
            the transcription factor Helios in stroke and their potential role
            in stroke-associated infection: a prospective case-control study.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 451)
  AUTHORS   Mohajeri,A., Vaseghi-Shanjani,M., Rosenfeld,J.A., Yang,G.X., Lu,H.,
            Sharma,M., Lin,S., Salman,A., Waqas,M., Sababi Azamian,M.,
            Worley,K.C., Del Bel,K.L., Kozak,F.K., Rahmanian,R., Biggs,C.M.,
            Hildebrand,K.J., Lalani,S.R., Nicholas,S.K., Scott,D.A.,
            Mostafavi,S., van Karnebeek,C., Henkelman,E., Halparin,J.,
            Yang,C.L., Armstrong,L., Turvey,S.E. and Lehman,A.
  CONSRTM   Undiagnosed Diseases Network; Care4Rare Canada Consortium
  TITLE     Dominant negative variants in IKZF2 cause ICHAD syndrome, a new
            disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay
  JOURNAL   J Med Genet 60 (11), 1092-1104 (2023)
   PUBMED   37316189
  REMARK    GeneRIF: Dominant negative variants in IKZF2 cause ICHAD syndrome,
            a new disorder characterised by immunodysregulation, craniofacial
            anomalies, hearing impairment, athelia and developmental delay.
REFERENCE   4  (residues 1 to 451)
  AUTHORS   Tarighi,M., Shahbazi,M., Saadat,P., Daraei,A., Alizadeh Khatir,A.,
            Rahimifard,K. and Mohammadnia-Afrouzi,M.
  TITLE     Decreased frequency of regulatory T cells and level of helios gene
            expression in secondary progressive multiple sclerosis patients:
            Evidence about the development of multiple sclerosis
  JOURNAL   Int Immunopharmacol 116, 109797 (2023)
   PUBMED   36738680
  REMARK    GeneRIF: Decreased frequency of regulatory T cells and level of
            helios gene expression in secondary progressive multiple sclerosis
            patients: Evidence about the development of multiple sclerosis.
REFERENCE   5  (residues 1 to 451)
  AUTHORS   Zhang,H., Jadhav,R.R., Cao,W., Goronzy,I.N., Zhao,T.V., Jin,J.,
            Ohtsuki,S., Hu,Z., Morales,J., Greenleaf,W.J., Weyand,C.M. and
            Goronzy,J.J.
  TITLE     Aging-associated HELIOS deficiency in naive CD4+ T cells alters
            chromatin remodeling and promotes effector cell responses
  JOURNAL   Nat Immunol 24 (1), 96-109 (2023)
   PUBMED   36510022
  REMARK    GeneRIF: Aging-associated HELIOS deficiency in naive CD4[+] T cells
            alters chromatin remodeling and promotes effector cell responses.
REFERENCE   6  (residues 1 to 451)
  AUTHORS   Nakase,K., Ishimaru,F., Fujii,K., Tabayashi,T., Kozuka,T.,
            Sezaki,N., Matsuo,Y. and Harada,M.
  TITLE     Overexpression of novel short isoforms of Helios in a patient with
            T-cell acute lymphoblastic leukemia
  JOURNAL   Exp Hematol 30 (4), 313-317 (2002)
   PUBMED   11937265
  REMARK    GeneRIF: Novel short isoforms of Helios are overexpressed in a
            patient with T-cell acute lymphoblastic leukemia and may contribute
            to the development of T-cell malignancies. Data for unaltered
            Helios indicates tumor suppressor function.
REFERENCE   7  (residues 1 to 451)
  AUTHORS   Perdomo,J., Holmes,M., Chong,B. and Crossley,M.
  TITLE     Eos and pegasus, two members of the Ikaros family of proteins with
            distinct DNA binding activities
  JOURNAL   J Biol Chem 275 (49), 38347-38354 (2000)
   PUBMED   10978333
REFERENCE   8  (residues 1 to 451)
  AUTHORS   Hosokawa,Y., Maeda,Y. and Seto,M.
  TITLE     Human Helios, an Ikaros-related zinc finger DNA binding protein:
            cDNA cloning and tissue expression pattern
  JOURNAL   Immunogenetics 50 (1-2), 106-108 (1999)
   PUBMED   10541817
REFERENCE   9  (residues 1 to 451)
  AUTHORS   Kelley,C.M., Ikeda,T., Koipally,J., Avitahl,N., Wu,L.,
            Georgopoulos,K. and Morgan,B.A.
  TITLE     Helios, a novel dimerization partner of Ikaros expressed in the
            earliest hematopoietic progenitors
  JOURNAL   Curr Biol 8 (9), 508-515 (1998)
   PUBMED   9560339
REFERENCE   10 (residues 1 to 451)
  AUTHORS   Hahm,K., Cobb,B.S., McCarty,A.S., Brown,K.E., Klug,C.A., Lee,R.,
            Akashi,K., Weissman,I.L., Fisher,A.G. and Smale,S.T.
  TITLE     Helios, a T cell-restricted Ikaros family member that
            quantitatively associates with Ikaros at centromeric
            heterochromatin
  JOURNAL   Genes Dev 12 (6), 782-796 (1998)
   PUBMED   9512513
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC079610.4, AC013736.9 and
            AC108066.3.
            
            Summary: This gene encodes a member of the Ikaros family of
            zinc-finger proteins. Three members of this protein family (Ikaros,
            Aiolos and Helios) are hematopoietic-specific transcription factors
            involved in the regulation of lymphocyte development. This protein
            forms homo- or hetero-dimers with other Ikaros family members, and
            is thought to function predominantly in early hematopoietic
            development. Multiple transcript variants encoding different
            isoforms have been found for this gene, but the biological validity
            of some variants has not been determined. [provided by RefSeq, Jul
            2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA2142853, SAMEA2144333
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q34"
     Protein         1..451
                     /product="zinc finger protein Helios isoform 3"
                     /note="zinc finger protein, subfamily 1A, 2 (Helios); zinc
                     finger DNA binding protein Helios; zinc finger protein
                     Helios; ikaros family zinc finger protein 2"
                     /calculated_mol_wt=51135
     Region          106..>423
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          115..135
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(120,122,124,126..127,130..131,134,148,150,154..155,
                     158..159,162,176,178,180,182..183,186..187,191)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          143..163
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          171..192
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..451
                     /gene="IKZF2"
                     /gene_synonym="ANF1A2; HELIOS; ICHAD; IMDIA; ZNF1A2;
                     ZNFN1A2"
                     /coded_by="NM_001371277.1:347..1702"
                     /note="isoform 3 is encoded by transcript variant 6"
                     /db_xref="GeneID:22807"
                     /db_xref="HGNC:HGNC:13177"
                     /db_xref="MIM:606234"
ORIGIN      
        1 meteaidgyi tcdnelsper ehsnmaidlt sstpngqhas pshmttnsvk lemqsdeecd
       61 rkplsredei rghdegssle epliesseva dnrkvqelqg eggirlpnge rpfhcnqcga
      121 sftqkgnllr hiklhsgekp fkcpfcsyac rrrdaltghl rthsvgkphk cnycgrsykq
      181 rssleehker chnylqnvsm eaagqvmshh geklmrfsyp dihfdmnlty ekeaelmqsh
      241 mmdqainnai tylgaealhp lmqhppstia evapvissay sqvyhpnrie rpisretads
      301 hennmdgpis lirpksrpqe reaspsnscl dstdsesshd dhqsyqghpa lnpkrkqspa
      361 ymkedvkald ttkapkgslk diykvfngeg eqirafkceh crvlfldhvm ytihmgchgy
      421 rdplecnicg yrsqdryefs shivrgehtf h
//
LOCUS       NP_001266527             317 aa            linear   VRT 18-JUN-2025
DEFINITION  annexin A5b [Oreochromis niloticus].
ACCESSION   NP_001266527 XP_003449732
VERSION     NP_001266527.1
DBSOURCE    REFSEQ: accession NM_001279598.1
KEYWORDS    RefSeq.
SOURCE      Oreochromis niloticus (Nile tilapia)
  ORGANISM  Oreochromis niloticus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes;
            Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini;
            Oreochromis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from DQ915162.1.
            
            On Jul 22, 2013 this sequence version replaced XP_003449732.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ915162.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN07788117 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Oreochromis niloticus"
                     /db_xref="taxon:8128"
                     /map="LG6"
                     /linkage_group="LG6"
     Protein         1..317
                     /product="annexin A5b"
                     /note="annexin A5; annexin A10"
                     /calculated_mol_wt=34657
     Region          18..82
                     /region_name="Annexin"
                     /note="pfam00191"
                     /db_xref="CDD:395139"
     Region          89..154
                     /region_name="Annexin"
                     /note="pfam00191"
                     /db_xref="CDD:395139"
     Region          171..236
                     /region_name="Annexin"
                     /note="pfam00191"
                     /db_xref="CDD:395139"
     Region          246..311
                     /region_name="Annexin"
                     /note="pfam00191"
                     /db_xref="CDD:395139"
     CDS             1..317
                     /gene="anxa5b"
                     /gene_synonym="anxa10"
                     /coded_by="NM_001279598.1:165..1118"
                     /db_xref="GeneID:100534399"
ORIGIN      
        1 manrgtvkps tnfnasadae vlhkamkglg tnedailqlv tarsnaqrqe ikasyktlyg
       61 kdligdlkge lggkfetliv almtspityd vtslhnaikg agtdekvlve ilasrtsqqv
      121 kqivaaykqe ydhdlekdit gdtsghfqrl lvillqanrq tgiqaesies daqalfkage
      181 qkfgtdeqsf vtilgnrsae hlrkvfdaym klsgyeiees ikretsgnlk dlllavvkca
      241 rsvpayfaet lyyamkgsgt ddntlirvmv trseadlldi raqfrrlfac slhsmikgdt
      301 sgdyrkalla lcggdda
//
LOCUS       NP_079163                334 aa            linear   PRI 18-JUN-2025
DEFINITION  dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform
            2 [Homo sapiens].
ACCESSION   NP_079163
VERSION     NP_079163.2
DBSOURCE    REFSEQ: accession NM_024887.4
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 334)
  AUTHORS   Williams,L.J., Waller,S., Qiu,J., Innes,E., Elserafy,N.,
            Procopis,P., Sampaio,H., Mahant,N., Tchan,M.C., Mohammad,S.S.,
            Morales-Briceno,H. and Fung,V.S.C.
  TITLE     DHDDS and NUS1: A Converging Pathway and Common Phenotype
  JOURNAL   Mov Disord Clin Pract 11 (1), 76-85 (2024)
   PUBMED   38291835
  REMARK    Review article
REFERENCE   2  (residues 1 to 334)
  AUTHORS   Jiao,X., Xue,Y., Yang,S., Gong,P., Niu,Y., Wang,Q., Yang,H.,
            Xiong,H., Zhang,Y. and Yang,Z.
  TITLE     Phenotype of heterozygous variants of dehydrodolichol diphosphate
            synthase
  JOURNAL   Dev Med Child Neurol 64 (1), 125-134 (2022)
   PUBMED   34275143
  REMARK    GeneRIF: Phenotype of heterozygous variants of dehydrodolichol
            diphosphate synthase.
REFERENCE   3  (residues 1 to 334)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (residues 1 to 334)
  AUTHORS   Bar-El,M.L., Vankova,P., Yeheskel,A., Simhaev,L., Engel,H., Man,P.,
            Haitin,Y. and Giladi,M.
  TITLE     Structural basis of heterotetrameric assembly and disease mutations
            in the human cis-prenyltransferase complex
  JOURNAL   Nat Commun 11 (1), 5273 (2020)
   PUBMED   33077723
  REMARK    GeneRIF: Structural basis of heterotetrameric assembly and disease
            mutations in the human cis-prenyltransferase complex.
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 334)
  AUTHORS   Jones,J., Viswanathan,K., Krag,S.S. and Betenbaugh,M.J.
  TITLE     Polyprenyl lipid synthesis in mammalian cells expressing human
            cis-prenyl transferase
  JOURNAL   Biochem Biophys Res Commun 331 (2), 379-383 (2005)
   PUBMED   15850770
  REMARK    GeneRIF: molecular cloning; results suggest a regulatory
            relationship between CPT activity and dolichol biosynthesis, and
            may implicate CPT in the levels of dolichol-oligosaccharide
            intermediate biosynthesis
REFERENCE   6  (residues 1 to 334)
  AUTHORS   Kharel,Y., Takahashi,S., Yamashita,S. and Koyama,T.
  TITLE     In vivo interaction between the human dehydrodolichyl diphosphate
            synthase and the Niemann-Pick C2 protein revealed by a yeast
            two-hybrid system
  JOURNAL   Biochem Biophys Res Commun 318 (1), 198-203 (2004)
   PUBMED   15110773
REFERENCE   7  (residues 1 to 334)
  AUTHORS   Shridas,P., Rush,J.S. and Waechter,C.J.
  TITLE     Identification and characterization of a cDNA encoding a long-chain
            cis-isoprenyltranferase involved in dolichyl monophosphate
            biosynthesis in the ER of brain cells
  JOURNAL   Biochem Biophys Res Commun 312 (4), 1349-1356 (2003)
   PUBMED   14652022
  REMARK    GeneRIF: identification and characterization; overexpression of CIT
            in CHO cells results in a modest increase in
            cis-isoprenyltransferase activity associated with microsomal
            fractions
REFERENCE   8  (residues 1 to 334)
  AUTHORS   Endo,S., Zhang,Y.W., Takahashi,S. and Koyama,T.
  TITLE     Identification of human dehydrodolichyl diphosphate synthase gene
  JOURNAL   Biochim Biophys Acta 1625 (3), 291-295 (2003)
   PUBMED   12591616
  REMARK    GeneRIF: identification and amino acid sequence expressed in yeast
REFERENCE   9  (residues 1 to 334)
  AUTHORS   Fahim,A.T., Daiger,S.P. and Weleber,R.G.
  TITLE     Nonsyndromic Retinitis Pigmentosa Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301590
REFERENCE   10 (residues 1 to 334)
  AUTHORS   Sparks,S.E. and Krasnewich,D.M.
  TITLE     Congenital Disorders of N-Linked Glycosylation and Multiple Pathway
            Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301507
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX648507.1, AK023164.1 and
            AW294595.1.
            
            On Mar 18, 2004 this sequence version replaced NP_079163.1.
            
            Summary: The protein encoded by this gene catalyzes cis-prenyl
            chain elongation to produce the polyprenyl backbone of dolichol, a
            glycosyl carrier lipid required for the biosynthesis of several
            classes of glycoproteins. Mutations in this gene are associated
            with retinitis pigmentosa type 59. Alternatively spliced transcript
            variants encoding different isoforms have been described for this
            gene. [provided by RefSeq, Aug 2011].
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            acceptor splice site at the 3' terminal exon compared to variant 1.
            This results in an isoform (2), which is 1 aa longer than isoform
            1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK023164.1, SRR14038195.660240.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     Protein         1..334
                     /product="dehydrodolichyl diphosphate synthase complex
                     subunit DHDDS isoform 2"
                     /EC_number="2.5.1.87"
                     /note="cis-prenyl transferase; cis-isoprenyltransferase;
                     dedol-PP synthase; cis-IPTase; epididymis tissue protein
                     Li 189m; dehydrodolichyl diphosphate syntase complex
                     subunit DHDDS; cis-prenyltransferase subunit hCIT;
                     dehydrodolichyl diphosphate synthase complex subunit
                     DHDDS"
                     /calculated_mol_wt=38655
     Region          28..248
                     /region_name="Cis_IPPS"
                     /note="Cis (Z)-Isoprenyl Diphosphate Synthases; cd00475"
                     /db_xref="CDD:259850"
     Site            order(33..38,47,51,55,58,77,85,89,96..97,100,152,205,211,
                     213)
                     /site_type="active"
                     /db_xref="CDD:259850"
     Site            order(159..160,162..163,166..167,183..185,188,199,
                     210..214,217..219,221..225,227)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:259850"
     CDS             1..334
                     /gene="DHDDS"
                     /gene_synonym="CIT; CPT; DEDSM; DS; hCIT; HDS; RP59"
                     /coded_by="NM_024887.4:112..1116"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="CCDS:CCDS281.1"
                     /db_xref="GeneID:79947"
                     /db_xref="HGNC:HGNC:20603"
                     /db_xref="MIM:608172"
ORIGIN      
        1 mswikegels lwerfcanii kagpmpkhia fimdgnrrya kkcqverqeg hsqgfnklae
       61 tlrwclnlgi levtvyafsi enfkrsksev dglmdlarqk fsrlmeekek lqkhgvcirv
      121 lgdlhllpld lqeliaqavq atknynkcfl nvcfaytsrh eisnavrema wgveqglldp
      181 sdiseslldk clytnrsphp dilirtsgev rlsdfllwqt shsclvfqpv lwpeytfwnl
      241 feailqfqmn hsvlqqkard myaeerkrqq lerdqatvte qllreglqas gdaqlrrtrl
      301 hklsarreer vqgflqalel kradwlarlg tasa
//
LOCUS       NP_060734                732 aa            linear   PRI 18-JUN-2025
DEFINITION  S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
            TYW1 [Homo sapiens].
ACCESSION   NP_060734
VERSION     NP_060734.2
DBSOURCE    REFSEQ: accession NM_018264.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 732)
  AUTHORS   Young,A.P. and Bandarian,V.
  TITLE     Eukaryotic TYW1 Is a Radical SAM Flavoenzyme
  JOURNAL   Biochemistry 60 (27), 2179-2185 (2021)
   PUBMED   34184886
REFERENCE   2  (residues 1 to 732)
  AUTHORS   Noma,A. and Suzuki,T.
  TITLE     Ribonucleome analysis identified enzyme genes responsible for
            wybutosine synthesis
  JOURNAL   Nucleic Acids Symp Ser (Oxf) (50), 65-66 (2006)
   PUBMED   17150819
REFERENCE   3  (residues 1 to 732)
  AUTHORS   Waas,W.F., de Crecy-Lagard,V. and Schimmel,P.
  TITLE     Discovery of a gene family critical to wyosine base formation in a
            subset of phenylalanine-specific transfer RNAs
  JOURNAL   J Biol Chem 280 (45), 37616-37622 (2005)
   PUBMED   16162496
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC079920.6, AC073089.5 and
            AC006480.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jul 28, 2004 this sequence version replaced NP_060734.1.
            
            Summary: Wybutosine (yW) is a hypermodified guanosine found in
            phenylalanine tRNA adjacent to the anticodon that stabilizes
            codon-anticodon interactions in the ribosome. In yeast, the homolog
            of this gene is essential for the synthesis of wybutosine.
            Alternative splicing results in multiple transcript variants.
            [provided by RefSeq, Dec 2015].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the functional protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC015591.2, SRR1660809.63784.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000359626.10/ ENSP00000352645.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q11.21"
     Protein         1..732
                     /product="S-adenosyl-L-methionine-dependent tRNA
                     4-demethylwyosine synthase TYW1"
                     /EC_number="4.1.3.44"
                     /note="radical S-adenosyl methionine and flavodoxin
                     domains 1; tRNA-yW synthesizing protein 1 homolog A; tRNA
                     wybutosine-synthesizing protein 1 homolog; radical
                     S-adenosyl methionine and flavodoxin domain-containing
                     protein 1"
                     /calculated_mol_wt=83571
     Region          81..>246
                     /region_name="CysJ"
                     /note="Flavoprotein (flavin reductase) subunit CysJ of
                     sulfite and N-hydroxylaminopurine reductases [Nucleotide
                     transport and metabolism, Inorganic ion transport and
                     metabolism]; COG0369"
                     /db_xref="CDD:440138"
     Region          248..314
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9NV66.2)"
     Region          360..656
                     /region_name="rSAM_TYW1"
                     /note="wyosine biosynthesis protein TYW1; TIGR03972"
                     /db_xref="CDD:274890"
     CDS             1..732
                     /gene="TYW1"
                     /gene_synonym="RSAFD1; TYW1A; YPL207W"
                     /coded_by="NM_018264.4:147..2345"
                     /db_xref="CCDS:CCDS5538.1"
                     /db_xref="GeneID:55253"
                     /db_xref="HGNC:HGNC:25598"
                     /db_xref="MIM:611243"
ORIGIN      
        1 mdpsadtwdl fsplislwin rfyiylgfav sislwicvqi viktqgknlq eksvpkaaqd
       61 lmtngyvslq ekdifvsgvk ifygsqtgta kgfatvlaea vtsldlpvai inlkeydpdd
      121 hlieevtskn vcvflvatyt dglptesaew fckwleeasi dfrfgktylk gmryavfglg
      181 nsayashfnk vgknvdkwlw mlgahrvmsr gegdcdvvks khgsieadfr awktkfisql
      241 qalqkgerkk scgghckkgk ceshqhgsee reegsheqde lhhrdteeee pfessseeef
      301 ggedhqslns ivdvedlgki mdhvkkekre keqqeeksgl frnmgrnedg erramitpal
      361 realtkqgyq ligshsgvkl crwtksmlrg rggcykhtfy gieshrcmet tpslacankc
      421 vfcwrhhtnp vgtewrwkmd qpemilkeai enhqnmikqf kgvpgvkaer feegmtvkhc
      481 alslvgepim ypeinrflkl lhqckissfl vtnaqfpaei rnlepvtqly vsvdastkds
      541 lkkidrplfk dfwqrfldsl kalavkqqrt vyrltlvkaw nvdelqayaq lvslgnpdfi
      601 evkgvtycge ssassltmah vpwheevvqf vhelvdlipe yeiacehehs nclliahrkf
      661 kiggewwtwi dynrfqeliq eyedsggskt fsakdymart phwalfgase rgfdpkdtrh
      721 qrknkskais gc
//
LOCUS       NP_001230493             299 aa            linear   PRI 18-JUN-2025
DEFINITION  dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform
            3 [Homo sapiens].
ACCESSION   NP_001230493
VERSION     NP_001230493.1
DBSOURCE    REFSEQ: accession NM_001243564.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 299)
  AUTHORS   Williams,L.J., Waller,S., Qiu,J., Innes,E., Elserafy,N.,
            Procopis,P., Sampaio,H., Mahant,N., Tchan,M.C., Mohammad,S.S.,
            Morales-Briceno,H. and Fung,V.S.C.
  TITLE     DHDDS and NUS1: A Converging Pathway and Common Phenotype
  JOURNAL   Mov Disord Clin Pract 11 (1), 76-85 (2024)
   PUBMED   38291835
  REMARK    Review article
REFERENCE   2  (residues 1 to 299)
  AUTHORS   Jiao,X., Xue,Y., Yang,S., Gong,P., Niu,Y., Wang,Q., Yang,H.,
            Xiong,H., Zhang,Y. and Yang,Z.
  TITLE     Phenotype of heterozygous variants of dehydrodolichol diphosphate
            synthase
  JOURNAL   Dev Med Child Neurol 64 (1), 125-134 (2022)
   PUBMED   34275143
  REMARK    GeneRIF: Phenotype of heterozygous variants of dehydrodolichol
            diphosphate synthase.
REFERENCE   3  (residues 1 to 299)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (residues 1 to 299)
  AUTHORS   Bar-El,M.L., Vankova,P., Yeheskel,A., Simhaev,L., Engel,H., Man,P.,
            Haitin,Y. and Giladi,M.
  TITLE     Structural basis of heterotetrameric assembly and disease mutations
            in the human cis-prenyltransferase complex
  JOURNAL   Nat Commun 11 (1), 5273 (2020)
   PUBMED   33077723
  REMARK    GeneRIF: Structural basis of heterotetrameric assembly and disease
            mutations in the human cis-prenyltransferase complex.
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 299)
  AUTHORS   Jones,J., Viswanathan,K., Krag,S.S. and Betenbaugh,M.J.
  TITLE     Polyprenyl lipid synthesis in mammalian cells expressing human
            cis-prenyl transferase
  JOURNAL   Biochem Biophys Res Commun 331 (2), 379-383 (2005)
   PUBMED   15850770
  REMARK    GeneRIF: molecular cloning; results suggest a regulatory
            relationship between CPT activity and dolichol biosynthesis, and
            may implicate CPT in the levels of dolichol-oligosaccharide
            intermediate biosynthesis
REFERENCE   6  (residues 1 to 299)
  AUTHORS   Kharel,Y., Takahashi,S., Yamashita,S. and Koyama,T.
  TITLE     In vivo interaction between the human dehydrodolichyl diphosphate
            synthase and the Niemann-Pick C2 protein revealed by a yeast
            two-hybrid system
  JOURNAL   Biochem Biophys Res Commun 318 (1), 198-203 (2004)
   PUBMED   15110773
REFERENCE   7  (residues 1 to 299)
  AUTHORS   Shridas,P., Rush,J.S. and Waechter,C.J.
  TITLE     Identification and characterization of a cDNA encoding a long-chain
            cis-isoprenyltranferase involved in dolichyl monophosphate
            biosynthesis in the ER of brain cells
  JOURNAL   Biochem Biophys Res Commun 312 (4), 1349-1356 (2003)
   PUBMED   14652022
  REMARK    GeneRIF: identification and characterization; overexpression of CIT
            in CHO cells results in a modest increase in
            cis-isoprenyltransferase activity associated with microsomal
            fractions
REFERENCE   8  (residues 1 to 299)
  AUTHORS   Endo,S., Zhang,Y.W., Takahashi,S. and Koyama,T.
  TITLE     Identification of human dehydrodolichyl diphosphate synthase gene
  JOURNAL   Biochim Biophys Acta 1625 (3), 291-295 (2003)
   PUBMED   12591616
  REMARK    GeneRIF: identification and amino acid sequence expressed in yeast
REFERENCE   9  (residues 1 to 299)
  AUTHORS   Fahim,A.T., Daiger,S.P. and Weleber,R.G.
  TITLE     Nonsyndromic Retinitis Pigmentosa Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301590
REFERENCE   10 (residues 1 to 299)
  AUTHORS   Sparks,S.E. and Krasnewich,D.M.
  TITLE     Congenital Disorders of N-Linked Glycosylation and Multiple Pathway
            Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301507
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX648507.1, AK316485.1,
            AK297134.1, AK023164.1 and AW294595.1.
            
            Summary: The protein encoded by this gene catalyzes cis-prenyl
            chain elongation to produce the polyprenyl backbone of dolichol, a
            glycosyl carrier lipid required for the biosynthesis of several
            classes of glycoproteins. Mutations in this gene are associated
            with retinitis pigmentosa type 59. Alternatively spliced transcript
            variants encoding different isoforms have been described for this
            gene. [provided by RefSeq, Aug 2011].
            
            Transcript Variant: This variant (3) lacks an in-frame coding exon
            compared to variant 1. This results in a shorter isoform (3)
            missing an internal protein segment compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074967.3965593.1,
                                           SRR14038194.874049.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     Protein         1..299
                     /product="dehydrodolichyl diphosphate synthase complex
                     subunit DHDDS isoform 3"
                     /EC_number="2.5.1.87"
                     /note="cis-prenyl transferase; cis-isoprenyltransferase;
                     dedol-PP synthase; cis-IPTase; epididymis tissue protein
                     Li 189m; dehydrodolichyl diphosphate syntase complex
                     subunit DHDDS; cis-prenyltransferase subunit hCIT;
                     dehydrodolichyl diphosphate synthase complex subunit
                     DHDDS"
                     /calculated_mol_wt=34686
     Region          28..214
                     /region_name="Cis_IPPS"
                     /note="Cis (Z)-Isoprenyl Diphosphate Synthases; cd00475"
                     /db_xref="CDD:259850"
     Site            order(33..38,47,51,55,58,77,85,89,96..97,100,171,177,179)
                     /site_type="active"
                     /db_xref="CDD:259850"
     CDS             1..299
                     /gene="DHDDS"
                     /gene_synonym="CIT; CPT; DEDSM; DS; hCIT; HDS; RP59"
                     /coded_by="NM_001243564.2:112..1011"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS57983.1"
                     /db_xref="GeneID:79947"
                     /db_xref="HGNC:HGNC:20603"
                     /db_xref="MIM:608172"
ORIGIN      
        1 mswikegels lwerfcanii kagpmpkhia fimdgnrrya kkcqverqeg hsqgfnklae
       61 tlrwclnlgi levtvyafsi enfkrsksev dglmdlarqk fsrlmeekek lqkhgvcirv
      121 lgdlhllpld lqeliaqavq atknynndis eslldkclyt nrsphpdili rtsgevrlsd
      181 fllwqtshsc lvfqpvlwpe ytfwnlfeai lqfqmnhsvl qkardmyaee rkrqqlerdq
      241 atvteqllre glqasgdaql rrtrlhklsa rreervqgfl qalelkradw larlgtasa
//
LOCUS       NP_001306888             240 aa            linear   PRI 18-JUN-2025
DEFINITION  dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform
            5 [Homo sapiens].
ACCESSION   NP_001306888 XP_006710982
VERSION     NP_001306888.1
DBSOURCE    REFSEQ: accession NM_001319959.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 240)
  AUTHORS   Williams,L.J., Waller,S., Qiu,J., Innes,E., Elserafy,N.,
            Procopis,P., Sampaio,H., Mahant,N., Tchan,M.C., Mohammad,S.S.,
            Morales-Briceno,H. and Fung,V.S.C.
  TITLE     DHDDS and NUS1: A Converging Pathway and Common Phenotype
  JOURNAL   Mov Disord Clin Pract 11 (1), 76-85 (2024)
   PUBMED   38291835
  REMARK    Review article
REFERENCE   2  (residues 1 to 240)
  AUTHORS   Jiao,X., Xue,Y., Yang,S., Gong,P., Niu,Y., Wang,Q., Yang,H.,
            Xiong,H., Zhang,Y. and Yang,Z.
  TITLE     Phenotype of heterozygous variants of dehydrodolichol diphosphate
            synthase
  JOURNAL   Dev Med Child Neurol 64 (1), 125-134 (2022)
   PUBMED   34275143
  REMARK    GeneRIF: Phenotype of heterozygous variants of dehydrodolichol
            diphosphate synthase.
REFERENCE   3  (residues 1 to 240)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (residues 1 to 240)
  AUTHORS   Bar-El,M.L., Vankova,P., Yeheskel,A., Simhaev,L., Engel,H., Man,P.,
            Haitin,Y. and Giladi,M.
  TITLE     Structural basis of heterotetrameric assembly and disease mutations
            in the human cis-prenyltransferase complex
  JOURNAL   Nat Commun 11 (1), 5273 (2020)
   PUBMED   33077723
  REMARK    GeneRIF: Structural basis of heterotetrameric assembly and disease
            mutations in the human cis-prenyltransferase complex.
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 240)
  AUTHORS   Jones,J., Viswanathan,K., Krag,S.S. and Betenbaugh,M.J.
  TITLE     Polyprenyl lipid synthesis in mammalian cells expressing human
            cis-prenyl transferase
  JOURNAL   Biochem Biophys Res Commun 331 (2), 379-383 (2005)
   PUBMED   15850770
  REMARK    GeneRIF: molecular cloning; results suggest a regulatory
            relationship between CPT activity and dolichol biosynthesis, and
            may implicate CPT in the levels of dolichol-oligosaccharide
            intermediate biosynthesis
REFERENCE   6  (residues 1 to 240)
  AUTHORS   Kharel,Y., Takahashi,S., Yamashita,S. and Koyama,T.
  TITLE     In vivo interaction between the human dehydrodolichyl diphosphate
            synthase and the Niemann-Pick C2 protein revealed by a yeast
            two-hybrid system
  JOURNAL   Biochem Biophys Res Commun 318 (1), 198-203 (2004)
   PUBMED   15110773
REFERENCE   7  (residues 1 to 240)
  AUTHORS   Shridas,P., Rush,J.S. and Waechter,C.J.
  TITLE     Identification and characterization of a cDNA encoding a long-chain
            cis-isoprenyltranferase involved in dolichyl monophosphate
            biosynthesis in the ER of brain cells
  JOURNAL   Biochem Biophys Res Commun 312 (4), 1349-1356 (2003)
   PUBMED   14652022
  REMARK    GeneRIF: identification and characterization; overexpression of CIT
            in CHO cells results in a modest increase in
            cis-isoprenyltransferase activity associated with microsomal
            fractions
REFERENCE   8  (residues 1 to 240)
  AUTHORS   Endo,S., Zhang,Y.W., Takahashi,S. and Koyama,T.
  TITLE     Identification of human dehydrodolichyl diphosphate synthase gene
  JOURNAL   Biochim Biophys Acta 1625 (3), 291-295 (2003)
   PUBMED   12591616
  REMARK    GeneRIF: identification and amino acid sequence expressed in yeast
REFERENCE   9  (residues 1 to 240)
  AUTHORS   Fahim,A.T., Daiger,S.P. and Weleber,R.G.
  TITLE     Nonsyndromic Retinitis Pigmentosa Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301590
REFERENCE   10 (residues 1 to 240)
  AUTHORS   Sparks,S.E. and Krasnewich,D.M.
  TITLE     Congenital Disorders of N-Linked Glycosylation and Multiple Pathway
            Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301507
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX648507.1, DA756178.1,
            AL513365.27 and AW294595.1.
            
            On Feb 6, 2016 this sequence version replaced XP_006710982.1.
            
            Summary: The protein encoded by this gene catalyzes cis-prenyl
            chain elongation to produce the polyprenyl backbone of dolichol, a
            glycosyl carrier lipid required for the biosynthesis of several
            classes of glycoproteins. Mutations in this gene are associated
            with retinitis pigmentosa type 59. Alternatively spliced transcript
            variants encoding different isoforms have been described for this
            gene. [provided by RefSeq, Aug 2011].
            
            Transcript Variant: This variant (5) uses an alternate splice
            junction compared to variant 1. The resulting isoform (5) is
            shorter at the N-terminus compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX648507.1, SRR14038196.2392399.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..240
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     Protein         1..240
                     /product="dehydrodolichyl diphosphate synthase complex
                     subunit DHDDS isoform 5"
                     /EC_number="2.5.1.87"
                     /note="cis-prenyl transferase; cis-isoprenyltransferase;
                     dedol-PP synthase; cis-IPTase; epididymis tissue protein
                     Li 189m; dehydrodolichyl diphosphate syntase complex
                     subunit DHDDS; cis-prenyltransferase subunit hCIT;
                     dehydrodolichyl diphosphate synthase complex subunit
                     DHDDS"
                     /calculated_mol_wt=27780
     Region          <1..155
                     /region_name="Cis_IPPS"
                     /note="Cis (Z)-Isoprenyl Diphosphate Synthases; cd00475"
                     /db_xref="CDD:259850"
     Site            order(66..67,69..70,73..74,90..92,95,106,117..121,
                     124..126,128..132,134)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:259850"
     CDS             1..240
                     /gene="DHDDS"
                     /gene_synonym="CIT; CPT; DEDSM; DS; hCIT; HDS; RP59"
                     /coded_by="NM_001319959.2:414..1136"
                     /note="isoform 5 is encoded by transcript variant 5"
                     /db_xref="GeneID:79947"
                     /db_xref="HGNC:HGNC:20603"
                     /db_xref="MIM:608172"
ORIGIN      
        1 mdlarqkfsr lmeekeklqk hgvcirvlgd lhllpldlqe liaqavqatk nynkcflnvc
       61 faytsrheis navremawgv eqglldpsdi seslldkcly tnrsphpdil irtsgevrls
      121 dfllwqtshs clvfqpvlwp eytfwnlfea ilqfqmnhsv lqkardmyae erkrqqlerd
      181 qatvteqllr eglqasgdaq lrrtrlhkls arreervqgf lqalelkrad wlarlgtasa
//
LOCUS       NP_001230494             294 aa            linear   PRI 18-JUN-2025
DEFINITION  dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform
            4 [Homo sapiens].
ACCESSION   NP_001230494
VERSION     NP_001230494.1
DBSOURCE    REFSEQ: accession NM_001243565.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 294)
  AUTHORS   Williams,L.J., Waller,S., Qiu,J., Innes,E., Elserafy,N.,
            Procopis,P., Sampaio,H., Mahant,N., Tchan,M.C., Mohammad,S.S.,
            Morales-Briceno,H. and Fung,V.S.C.
  TITLE     DHDDS and NUS1: A Converging Pathway and Common Phenotype
  JOURNAL   Mov Disord Clin Pract 11 (1), 76-85 (2024)
   PUBMED   38291835
  REMARK    Review article
REFERENCE   2  (residues 1 to 294)
  AUTHORS   Jiao,X., Xue,Y., Yang,S., Gong,P., Niu,Y., Wang,Q., Yang,H.,
            Xiong,H., Zhang,Y. and Yang,Z.
  TITLE     Phenotype of heterozygous variants of dehydrodolichol diphosphate
            synthase
  JOURNAL   Dev Med Child Neurol 64 (1), 125-134 (2022)
   PUBMED   34275143
  REMARK    GeneRIF: Phenotype of heterozygous variants of dehydrodolichol
            diphosphate synthase.
REFERENCE   3  (residues 1 to 294)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (residues 1 to 294)
  AUTHORS   Bar-El,M.L., Vankova,P., Yeheskel,A., Simhaev,L., Engel,H., Man,P.,
            Haitin,Y. and Giladi,M.
  TITLE     Structural basis of heterotetrameric assembly and disease mutations
            in the human cis-prenyltransferase complex
  JOURNAL   Nat Commun 11 (1), 5273 (2020)
   PUBMED   33077723
  REMARK    GeneRIF: Structural basis of heterotetrameric assembly and disease
            mutations in the human cis-prenyltransferase complex.
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 294)
  AUTHORS   Jones,J., Viswanathan,K., Krag,S.S. and Betenbaugh,M.J.
  TITLE     Polyprenyl lipid synthesis in mammalian cells expressing human
            cis-prenyl transferase
  JOURNAL   Biochem Biophys Res Commun 331 (2), 379-383 (2005)
   PUBMED   15850770
  REMARK    GeneRIF: molecular cloning; results suggest a regulatory
            relationship between CPT activity and dolichol biosynthesis, and
            may implicate CPT in the levels of dolichol-oligosaccharide
            intermediate biosynthesis
REFERENCE   6  (residues 1 to 294)
  AUTHORS   Kharel,Y., Takahashi,S., Yamashita,S. and Koyama,T.
  TITLE     In vivo interaction between the human dehydrodolichyl diphosphate
            synthase and the Niemann-Pick C2 protein revealed by a yeast
            two-hybrid system
  JOURNAL   Biochem Biophys Res Commun 318 (1), 198-203 (2004)
   PUBMED   15110773
REFERENCE   7  (residues 1 to 294)
  AUTHORS   Shridas,P., Rush,J.S. and Waechter,C.J.
  TITLE     Identification and characterization of a cDNA encoding a long-chain
            cis-isoprenyltranferase involved in dolichyl monophosphate
            biosynthesis in the ER of brain cells
  JOURNAL   Biochem Biophys Res Commun 312 (4), 1349-1356 (2003)
   PUBMED   14652022
  REMARK    GeneRIF: identification and characterization; overexpression of CIT
            in CHO cells results in a modest increase in
            cis-isoprenyltransferase activity associated with microsomal
            fractions
REFERENCE   8  (residues 1 to 294)
  AUTHORS   Endo,S., Zhang,Y.W., Takahashi,S. and Koyama,T.
  TITLE     Identification of human dehydrodolichyl diphosphate synthase gene
  JOURNAL   Biochim Biophys Acta 1625 (3), 291-295 (2003)
   PUBMED   12591616
  REMARK    GeneRIF: identification and amino acid sequence expressed in yeast
REFERENCE   9  (residues 1 to 294)
  AUTHORS   Fahim,A.T., Daiger,S.P. and Weleber,R.G.
  TITLE     Nonsyndromic Retinitis Pigmentosa Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301590
REFERENCE   10 (residues 1 to 294)
  AUTHORS   Sparks,S.E. and Krasnewich,D.M.
  TITLE     Congenital Disorders of N-Linked Glycosylation and Multiple Pathway
            Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301507
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX648507.1, BC004117.2,
            AK023164.1 and AW294595.1.
            
            Summary: The protein encoded by this gene catalyzes cis-prenyl
            chain elongation to produce the polyprenyl backbone of dolichol, a
            glycosyl carrier lipid required for the biosynthesis of several
            classes of glycoproteins. Mutations in this gene are associated
            with retinitis pigmentosa type 59. Alternatively spliced transcript
            variants encoding different isoforms have been described for this
            gene. [provided by RefSeq, Aug 2011].
            
            Transcript Variant: This variant (4) lacks an in-frame coding exon
            compared to variant 1. This results in a shorter isoform (4)
            missing an internal protein segment compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.151150.1,
                                           SRR14038194.3723806.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142670, SAMEA2144835
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     Protein         1..294
                     /product="dehydrodolichyl diphosphate synthase complex
                     subunit DHDDS isoform 4"
                     /EC_number="2.5.1.87"
                     /note="cis-prenyl transferase; cis-isoprenyltransferase;
                     dedol-PP synthase; cis-IPTase; epididymis tissue protein
                     Li 189m; dehydrodolichyl diphosphate syntase complex
                     subunit DHDDS; cis-prenyltransferase subunit hCIT;
                     dehydrodolichyl diphosphate synthase complex subunit
                     DHDDS"
                     /calculated_mol_wt=34133
     Region          28..209
                     /region_name="Cis_IPPS"
                     /note="Cis (Z)-Isoprenyl Diphosphate Synthases; cd00475"
                     /db_xref="CDD:259850"
     Site            order(33..38,47,51,55,58,77,85,89,96..97,100,113,166,172,
                     174)
                     /site_type="active"
                     /db_xref="CDD:259850"
     Site            order(120..121,123..124,127..128,144..146,149,160,
                     171..175,178..180,182..186,188)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:259850"
     CDS             1..294
                     /gene="DHDDS"
                     /gene_synonym="CIT; CPT; DEDSM; DS; hCIT; HDS; RP59"
                     /coded_by="NM_001243565.2:112..996"
                     /note="isoform 4 is encoded by transcript variant 4"
                     /db_xref="CCDS:CCDS57984.1"
                     /db_xref="GeneID:79947"
                     /db_xref="HGNC:HGNC:20603"
                     /db_xref="MIM:608172"
ORIGIN      
        1 mswikegels lwerfcanii kagpmpkhia fimdgnrrya kkcqverqeg hsqgfnklae
       61 tlrwclnlgi levtvyafsi enfkrsksev dglmdlarqk fsrlmeekcf lnvcfaytsr
      121 heisnavrem awgveqglld psdiseslld kclytnrsph pdilirtsge vrlsdfllwq
      181 tshsclvfqp vlwpeytfwn lfeailqfqm nhsvlqkard myaeerkrqq lerdqatvte
      241 qllreglqas gdaqlrrtrl hklsarreer vqgflqalel kradwlarlg tasa
//
LOCUS       NP_001287791             501 aa            linear   PRI 18-JUN-2025
DEFINITION  MPN domain-containing protein isoform 3 [Homo sapiens].
ACCESSION   NP_001287791 XP_005259720
VERSION     NP_001287791.1
DBSOURCE    REFSEQ: accession NM_001300862.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 501)
  AUTHORS   Yang,M., Li,X., Tian,Z., Ma,L., Ma,J., Liu,Y., Shang,G., Liang,A.,
            Wu,W. and Chen,Z.
  TITLE     Structures of MPND Reveal the Molecular Recognition of Nucleosomes
  JOURNAL   Int J Mol Sci 24 (4), 3368 (2023)
   PUBMED   36834777
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 501)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (residues 1 to 501)
  AUTHORS   Kweon,S.M., Chen,Y., Moon,E., Kvederaviciute,K., Klimasauskas,S.
            and Feldman,D.E.
  TITLE     An Adversarial DNA N6-Methyladenine-Sensor Network Preserves
            Polycomb Silencing
  JOURNAL   Mol Cell 74 (6), 1138-1147 (2019)
   PUBMED   30982744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007292.1.
            
            On Jul 15, 2014 this sequence version replaced XP_005259720.1.
            
            Transcript Variant: This variant (3) represents the longest
            transcript and encodes the longest isoform (3).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038194.4281748.1,
                                           SRR1163655.375461.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000599840.6/ ENSP00000471735.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     Protein         1..501
                     /product="MPN domain-containing protein isoform 3"
                     /note="MPN domain-containing protein"
                     /calculated_mol_wt=54029
     Region          70..164
                     /region_name="RAMA"
                     /note="Restriction Enzyme Adenine Methylase Associated;
                     pfam18755"
                     /db_xref="CDD:465856"
     Region          266..450
                     /region_name="MPN_2A_DUB"
                     /note="Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase;
                     cd08067"
                     /db_xref="CDD:163698"
     Site            order(292,349,351,359,362)
                     /site_type="active"
                     /note="MPN+ (JAMM) motif [active]"
                     /db_xref="CDD:163698"
     Site            order(349,351,362)
                     /site_type="other"
                     /note="Zinc-binding site [ion binding]"
                     /db_xref="CDD:163698"
     CDS             1..501
                     /gene="MPND"
                     /coded_by="NM_001300862.2:33..1538"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /db_xref="CCDS:CCDS74261.1"
                     /db_xref="GeneID:84954"
                     /db_xref="HGNC:HGNC:25934"
ORIGIN      
        1 maapeplspa ggageeapee dedeaeaedp erpnagaggg rsggggssvs gggggggaga
       61 ggcggpggal trravtlrvl lkdallepga gvlsiyylgk kflgdlqpdg rimwqetgqt
      121 fnspsawath ckklvnpakk sgcgwasvky kgqkldkyka twlrlhqlht pataadespa
      181 segeeeellm eeeeedvlag vsaedksrrp lgkspsepah peattpgkrv dskirvpvry
      241 cmlgsrdlar nphtlvevts faainkfqpf nvavssnvlf lldfhshltr sevvgylggr
      301 wdvnsqmltv lrafpcrsrl gdaetaaaie eeiyqslflr glslvgwyhs hphspalpsl
      361 qdidaqmdyq lrlqgssngf qpclallcsp yysgnpgpes kispfwvmpp peqrpsdygi
      421 pmdvemayvq dsfltndilh emmllvefyk gspdlvrlqe pwsqehtyld klkislasrt
      481 pkdqslchvl eqvcgvlkqg s
//
LOCUS       NP_001153318             451 aa            linear   PRI 18-JUN-2025
DEFINITION  MPN domain-containing protein isoform 2 [Homo sapiens].
ACCESSION   NP_001153318
VERSION     NP_001153318.1
DBSOURCE    REFSEQ: accession NM_001159846.3
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 451)
  AUTHORS   Yang,M., Li,X., Tian,Z., Ma,L., Ma,J., Liu,Y., Shang,G., Liang,A.,
            Wu,W. and Chen,Z.
  TITLE     Structures of MPND Reveal the Molecular Recognition of Nucleosomes
  JOURNAL   Int J Mol Sci 24 (4), 3368 (2023)
   PUBMED   36834777
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 451)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (residues 1 to 451)
  AUTHORS   Kweon,S.M., Chen,Y., Moon,E., Kvederaviciute,K., Klimasauskas,S.
            and Feldman,D.E.
  TITLE     An Adversarial DNA N6-Methyladenine-Sensor Network Preserves
            Polycomb Silencing
  JOURNAL   Mol Cell 74 (6), 1138-1147 (2019)
   PUBMED   30982744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007292.1.
            
            Transcript Variant: This variant (2) lacks two consecutive
            alternate exons in the 3' coding region, compared to variant 3. It
            encodes isoform 2, which lacks an internal in-frame segment and is
            shorter, compared to isoform 3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK027887.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     Protein         1..451
                     /product="MPN domain-containing protein isoform 2"
                     /note="MPN domain-containing protein"
                     /calculated_mol_wt=48455
     Region          70..164
                     /region_name="RAMA"
                     /note="Restriction Enzyme Adenine Methylase Associated;
                     pfam18755"
                     /db_xref="CDD:465856"
     Region          266..400
                     /region_name="MPN"
                     /note="Mpr1p, Pad1p N-terminal (MPN) domains; cl13996"
                     /db_xref="CDD:472685"
     CDS             1..451
                     /gene="MPND"
                     /coded_by="NM_001159846.3:33..1388"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="CCDS:CCDS54200.1"
                     /db_xref="GeneID:84954"
                     /db_xref="HGNC:HGNC:25934"
ORIGIN      
        1 maapeplspa ggageeapee dedeaeaedp erpnagaggg rsggggssvs gggggggaga
       61 ggcggpggal trravtlrvl lkdallepga gvlsiyylgk kflgdlqpdg rimwqetgqt
      121 fnspsawath ckklvnpakk sgcgwasvky kgqkldkyka twlrlhqlht pataadespa
      181 segeeeellm eeeeedvlag vsaedksrrp lgkspsepah peattpgkrv dskirvpvry
      241 cmlgsrdlar nphtlvevts faainkfqpf nvavssnvlf lliyqslflr glslvgwyhs
      301 hphspalpsl qdidaqmdyq lrlqgssngf qpclallcsp yysgnpgpes kispfwvmpp
      361 peqrpsdygi pmdvemayvq dsfltndilh emmllvefyk gspdlvrlqe pwsqehtyld
      421 klkislasrt pkdqslchvl eqvcgvlkqg s
//
LOCUS       NP_995583                333 aa            linear   PRI 18-JUN-2025
DEFINITION  dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform
            1 [Homo sapiens].
ACCESSION   NP_995583
VERSION     NP_995583.1
DBSOURCE    REFSEQ: accession NM_205861.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 333)
  AUTHORS   Williams,L.J., Waller,S., Qiu,J., Innes,E., Elserafy,N.,
            Procopis,P., Sampaio,H., Mahant,N., Tchan,M.C., Mohammad,S.S.,
            Morales-Briceno,H. and Fung,V.S.C.
  TITLE     DHDDS and NUS1: A Converging Pathway and Common Phenotype
  JOURNAL   Mov Disord Clin Pract 11 (1), 76-85 (2024)
   PUBMED   38291835
  REMARK    Review article
REFERENCE   2  (residues 1 to 333)
  AUTHORS   Jiao,X., Xue,Y., Yang,S., Gong,P., Niu,Y., Wang,Q., Yang,H.,
            Xiong,H., Zhang,Y. and Yang,Z.
  TITLE     Phenotype of heterozygous variants of dehydrodolichol diphosphate
            synthase
  JOURNAL   Dev Med Child Neurol 64 (1), 125-134 (2022)
   PUBMED   34275143
  REMARK    GeneRIF: Phenotype of heterozygous variants of dehydrodolichol
            diphosphate synthase.
REFERENCE   3  (residues 1 to 333)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (residues 1 to 333)
  AUTHORS   Bar-El,M.L., Vankova,P., Yeheskel,A., Simhaev,L., Engel,H., Man,P.,
            Haitin,Y. and Giladi,M.
  TITLE     Structural basis of heterotetrameric assembly and disease mutations
            in the human cis-prenyltransferase complex
  JOURNAL   Nat Commun 11 (1), 5273 (2020)
   PUBMED   33077723
  REMARK    GeneRIF: Structural basis of heterotetrameric assembly and disease
            mutations in the human cis-prenyltransferase complex.
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 333)
  AUTHORS   Jones,J., Viswanathan,K., Krag,S.S. and Betenbaugh,M.J.
  TITLE     Polyprenyl lipid synthesis in mammalian cells expressing human
            cis-prenyl transferase
  JOURNAL   Biochem Biophys Res Commun 331 (2), 379-383 (2005)
   PUBMED   15850770
  REMARK    GeneRIF: molecular cloning; results suggest a regulatory
            relationship between CPT activity and dolichol biosynthesis, and
            may implicate CPT in the levels of dolichol-oligosaccharide
            intermediate biosynthesis
REFERENCE   6  (residues 1 to 333)
  AUTHORS   Kharel,Y., Takahashi,S., Yamashita,S. and Koyama,T.
  TITLE     In vivo interaction between the human dehydrodolichyl diphosphate
            synthase and the Niemann-Pick C2 protein revealed by a yeast
            two-hybrid system
  JOURNAL   Biochem Biophys Res Commun 318 (1), 198-203 (2004)
   PUBMED   15110773
REFERENCE   7  (residues 1 to 333)
  AUTHORS   Shridas,P., Rush,J.S. and Waechter,C.J.
  TITLE     Identification and characterization of a cDNA encoding a long-chain
            cis-isoprenyltranferase involved in dolichyl monophosphate
            biosynthesis in the ER of brain cells
  JOURNAL   Biochem Biophys Res Commun 312 (4), 1349-1356 (2003)
   PUBMED   14652022
  REMARK    GeneRIF: identification and characterization; overexpression of CIT
            in CHO cells results in a modest increase in
            cis-isoprenyltransferase activity associated with microsomal
            fractions
REFERENCE   8  (residues 1 to 333)
  AUTHORS   Endo,S., Zhang,Y.W., Takahashi,S. and Koyama,T.
  TITLE     Identification of human dehydrodolichyl diphosphate synthase gene
  JOURNAL   Biochim Biophys Acta 1625 (3), 291-295 (2003)
   PUBMED   12591616
  REMARK    GeneRIF: identification and amino acid sequence expressed in yeast
REFERENCE   9  (residues 1 to 333)
  AUTHORS   Fahim,A.T., Daiger,S.P. and Weleber,R.G.
  TITLE     Nonsyndromic Retinitis Pigmentosa Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301590
REFERENCE   10 (residues 1 to 333)
  AUTHORS   Sparks,S.E. and Krasnewich,D.M.
  TITLE     Congenital Disorders of N-Linked Glycosylation and Multiple Pathway
            Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301507
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BX648507.1, BC003643.2,
            AB090852.1, AK023164.1 and AW294595.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The protein encoded by this gene catalyzes cis-prenyl
            chain elongation to produce the polyprenyl backbone of dolichol, a
            glycosyl carrier lipid required for the biosynthesis of several
            classes of glycoproteins. Mutations in this gene are associated
            with retinitis pigmentosa type 59. Alternatively spliced transcript
            variants encoding different isoforms have been described for this
            gene. [provided by RefSeq, Aug 2011].
            
            Transcript Variant: This variant (1) represents the predominant
            transcript, and encodes isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.194.1, SRR1803616.49989.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000236342.12/ ENSP00000236342.7
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     Protein         1..333
                     /product="dehydrodolichyl diphosphate synthase complex
                     subunit DHDDS isoform 1"
                     /EC_number="2.5.1.87"
                     /note="cis-prenyl transferase; cis-isoprenyltransferase;
                     dedol-PP synthase; cis-IPTase; epididymis tissue protein
                     Li 189m; dehydrodolichyl diphosphate syntase complex
                     subunit DHDDS; cis-prenyltransferase subunit hCIT;
                     dehydrodolichyl diphosphate synthase complex subunit
                     DHDDS"
                     /calculated_mol_wt=38526
     Region          28..248
                     /region_name="Cis_IPPS"
                     /note="Cis (Z)-Isoprenyl Diphosphate Synthases; cd00475"
                     /db_xref="CDD:259850"
     Site            order(33..38,47,51,55,58,77,85,89,96..97,100,152,205,211,
                     213)
                     /site_type="active"
                     /db_xref="CDD:259850"
     Site            order(159..160,162..163,166..167,183..185,188,199,
                     210..214,217..219,221..225,227)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:259850"
     CDS             1..333
                     /gene="DHDDS"
                     /gene_synonym="CIT; CPT; DEDSM; DS; hCIT; HDS; RP59"
                     /coded_by="NM_205861.3:112..1113"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS282.1"
                     /db_xref="GeneID:79947"
                     /db_xref="HGNC:HGNC:20603"
                     /db_xref="MIM:608172"
ORIGIN      
        1 mswikegels lwerfcanii kagpmpkhia fimdgnrrya kkcqverqeg hsqgfnklae
       61 tlrwclnlgi levtvyafsi enfkrsksev dglmdlarqk fsrlmeekek lqkhgvcirv
      121 lgdlhllpld lqeliaqavq atknynkcfl nvcfaytsrh eisnavrema wgveqglldp
      181 sdiseslldk clytnrsphp dilirtsgev rlsdfllwqt shsclvfqpv lwpeytfwnl
      241 feailqfqmn hsvlqkardm yaeerkrqql erdqatvteq llreglqasg daqlrrtrlh
      301 klsarreerv qgflqalelk radwlarlgt asa
//
LOCUS       NP_116257                471 aa            linear   PRI 18-JUN-2025
DEFINITION  MPN domain-containing protein isoform 1 [Homo sapiens].
ACCESSION   NP_116257
VERSION     NP_116257.2
DBSOURCE    REFSEQ: accession NM_032868.6
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 471)
  AUTHORS   Yang,M., Li,X., Tian,Z., Ma,L., Ma,J., Liu,Y., Shang,G., Liang,A.,
            Wu,W. and Chen,Z.
  TITLE     Structures of MPND Reveal the Molecular Recognition of Nucleosomes
  JOURNAL   Int J Mol Sci 24 (4), 3368 (2023)
   PUBMED   36834777
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 471)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (residues 1 to 471)
  AUTHORS   Kweon,S.M., Chen,Y., Moon,E., Kvederaviciute,K., Klimasauskas,S.
            and Feldman,D.E.
  TITLE     An Adversarial DNA N6-Methyladenine-Sensor Network Preserves
            Polycomb Silencing
  JOURNAL   Mol Cell 74 (6), 1138-1147 (2019)
   PUBMED   30982744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007292.1.
            
            On Jun 9, 2003 this sequence version replaced NP_116257.1.
            
            Transcript Variant: This variant (1) lacks an alternate in-frame
            exon in the 3' coding region, compared to variant 3. It encodes
            isoform 1, which lacks an internal segment and is shorter, compared
            to isoform 3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC032652.1, ERR4352443.591020.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA2152568
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     Protein         1..471
                     /product="MPN domain-containing protein isoform 1"
                     /note="MPN domain-containing protein"
                     /calculated_mol_wt=50531
     Region          1..63
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8N594.1)"
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (Q8N594.1)"
     Site            8
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (Q8N594.1)"
     Region          70..164
                     /region_name="RAMA"
                     /note="Restriction Enzyme Adenine Methylase Associated;
                     pfam18755"
                     /db_xref="CDD:465856"
     Region          170..229
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8N594.1)"
     Site            178
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17081983; propagated from
                     UniProtKB/Swiss-Prot (Q8N594.1)"
     Site            181
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:17081983; propagated from
                     UniProtKB/Swiss-Prot (Q8N594.1)"
     Region          266..443
                     /region_name="MPN_2A_DUB"
                     /note="Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase;
                     cd08067"
                     /db_xref="CDD:163698"
     Site            order(292,349,351,359,362)
                     /site_type="active"
                     /note="MPN+ (JAMM) motif [active]"
                     /db_xref="CDD:163698"
     Region          349..362
                     /region_name="JAMM motif.
                     /evidence=ECO:0000255|PROSITE-ProRule:PRU01182"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8N594.1)"
     Site            order(349,351,362)
                     /site_type="other"
                     /note="Zinc-binding site [ion binding]"
                     /db_xref="CDD:163698"
     CDS             1..471
                     /gene="MPND"
                     /coded_by="NM_032868.6:33..1448"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS42470.1"
                     /db_xref="GeneID:84954"
                     /db_xref="HGNC:HGNC:25934"
ORIGIN      
        1 maapeplspa ggageeapee dedeaeaedp erpnagaggg rsggggssvs gggggggaga
       61 ggcggpggal trravtlrvl lkdallepga gvlsiyylgk kflgdlqpdg rimwqetgqt
      121 fnspsawath ckklvnpakk sgcgwasvky kgqkldkyka twlrlhqlht pataadespa
      181 segeeeellm eeeeedvlag vsaedksrrp lgkspsepah peattpgkrv dskirvpvry
      241 cmlgsrdlar nphtlvevts faainkfqpf nvavssnvlf lldfhshltr sevvgylggr
      301 wdvnsqmltv lrafpcrsrl gdaetaaaie eeiyqslflr glslvgwyhs hphspalpsl
      361 qdidaqmdyq lrlqgssngf qpclallcsp yysgnpgpes kispfwvmpp pemllvefyk
      421 gspdlvrlqe pwsqehtyld klkislasrt pkdqslchvl eqvcgvlkqg s
//
LOCUS       NP_001315162             419 aa            linear   VRT 19-JUN-2025
DEFINITION  growth/differentiation factor 2 precursor [Cynoglossus semilaevis].
ACCESSION   NP_001315162 XP_008313025
VERSION     NP_001315162.1
DBSOURCE    REFSEQ: accession NM_001328233.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KC422337.1.
            
            On Jun 9, 2016 this sequence version replaced XP_008313025.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KC422337.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN04556680
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="8"
                     /map="8"
     Protein         1..419
                     /product="growth/differentiation factor 2 precursor"
                     /note="dorsalin-1-like protein"
                     /calculated_mol_wt=44170
     sig_peptide     1..24
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2565
     Region          37..>207
                     /region_name="TGFb_propeptide"
                     /note="TGF-beta propeptide; cl46657"
                     /db_xref="CDD:480997"
     Region          317..419
                     /region_name="TGF_beta_SF"
                     /note="transforming growth factor beta (TGF-beta) like
                     domain found in TGF-beta superfamily; cl40434"
                     /db_xref="CDD:477357"
     Site            order(323,325,344..348,382..386,389,409..411)
                     /site_type="other"
                     /note="homodimer interface 1 [polypeptide binding]"
                     /db_xref="CDD:381627"
     Site            order(382..383,385,405,409..410)
                     /site_type="other"
                     /note="homodimer interface 2 [polypeptide binding]"
                     /db_xref="CDD:381627"
     CDS             1..419
                     /gene="gdf2"
                     /coded_by="NM_001328233.1:154..1413"
                     /db_xref="GeneID:103382126"
ORIGIN      
        1 mlssrafllr vclslavysg sstckplsnd vesqdpegld iqlsdddlle kedvdmrmen
       61 llgnmkegfl kklnlsdvpq ehskmsppqf mmelynkyaa drstspqsdv irsfsvqdft
      121 islingtktk hrlqfnvtip shekivtsel qlfffpdnts itssksivkv hevghnltst
      181 tllegkevts shgvwasfdv taavegwsrs gcgatvldvv vdrkdcvapp ggdeaagcln
      241 vslsvggnts aavivfsddl ssrrqenkke lremihreee ailhsgadwn rggdlpneil
      301 eaqhprrtkr kasgreycrr tslkvnfkdi gwdswivapp eydayecrgl cyhpltdest
      361 pskhaliqtl inirdpgkan maccvpikld pitvmyqeng rltirylyee mkvaecgcr
//
LOCUS       NP_001281140             200 aa            linear   VRT 19-JUN-2025
DEFINITION  somatotropin precursor [Cynoglossus semilaevis].
ACCESSION   NP_001281140 XP_008320739
VERSION     NP_001281140.1
DBSOURCE    REFSEQ: accession NM_001294211.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 200)
  AUTHORS   Ma,Q., Liu,S., Zhuang,Z., Lin,L., Sun,Z., Liu,C., Ma,H., Su,Y. and
            Tang,Q.
  TITLE     Genomic structure, polymorphism and expression analysis of the
            growth hormone (GH) gene in female and male Half-smooth tongue sole
            (Cynoglossus semilaevis)
  JOURNAL   Gene 493 (1), 92-104 (2012)
   PUBMED   22120536
REFERENCE   2  (residues 1 to 200)
  AUTHORS   Ji,X.S., Liu,H.W., Chen,S.L., Jiang,Y.L. and Tian,Y.S.
  TITLE     Growth differences and dimorphic expression of growth hormone (GH)
            in female and male Cynoglossus semilaevis after male sexual
            maturation
  JOURNAL   Mar Genomics 4 (1), 9-16 (2011)
   PUBMED   21429460
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from HQ334196.1.
            
            On Jun 26, 2014 this sequence version replaced XP_008320739.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HQ334196.1, FJ608663.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN03753709
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..200
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="12"
                     /map="12"
     Protein         1..200
                     /product="somatotropin precursor"
                     /calculated_mol_wt=21287
     sig_peptide     1..17
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=1884
     Region          25..198
                     /region_name="somatotropin_like"
                     /note="Somatotropin or growth hormone (GH), placental
                     lactogen, and related pituitary gland hormones; cd10285"
                     /db_xref="CDD:198435"
     Site            order(25,28,31..32,34,37..38,41,57..58,61..62,64,75..78,
                     81..82,123,126..127,130,172,175..176,179..180,182..183,
                     186..187,190,198)
                     /site_type="other"
                     /note="receptor binding interface [polypeptide binding]"
                     /db_xref="CDD:198435"
     CDS             1..200
                     /gene="gh1"
                     /gene_synonym="GH"
                     /coded_by="NM_001294211.1:63..665"
                     /db_xref="GeneID:103387754"
ORIGIN      
        1 mdklvlllsm lcmsvstqpv idqrrfsiav skvqhlhlla qkyfsdfens lqtedqrqfn
       61 kfhqdfcnpd niiipdnkhe tqrssvlnll liskrlvdsr efsihfitwn lfprnqvlhr
      121 lsdlkkgiqm lieasdgaem sdsitlpvtp fgnfyenlgg nesqkrnyel lacfkkdmhk
      181 vetyltvakc rlspeanctl
//
LOCUS       NP_001415071             809 aa            linear   VRT 19-JUN-2025
DEFINITION  echinoderm microtubule-associated protein-like 2 isoform 2 [Xenopus
            tropicalis].
ACCESSION   NP_001415071 XP_012823785
VERSION     NP_001415071.1
DBSOURCE    REFSEQ: accession NM_001428142.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (residues 1 to 809)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AAMC04000008.1.
            
            On Feb 15, 2024 this sequence version replaced XP_012823785.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00028301,
                              SAMD00028302 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Xenopus tropicalis"
                     /db_xref="taxon:8364"
                     /chromosome="8"
                     /map="8"
     Protein         1..809
                     /product="echinoderm microtubule-associated protein-like 2
                     isoform 2"
                     /note="echinoderm microtubule associated protein like 1"
                     /calculated_mol_wt=88167
     CDS             1..809
                     /gene="eml1"
                     /coded_by="NM_001428142.1:68..2497"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /db_xref="GeneID:548488"
                     /db_xref="Xenbase:XB-GENE-949779"
ORIGIN      
        1 msesgaggss vydtssllqy cnddglsgps amdtddrisn leqrlqlqed emqvlraals
       61 dalrrlrice ergdairgrq svhivkpppr saqngtaprr rtglstspss pkmggtpvfv
      121 ksvrrslspe rmsflkrdis dtrsrvlatc sgrrdgkskq vvfypeegvv klylrgrsvp
      181 lyvpdslvas ysldakgelp trelqlewvy gyrgrdcrsn lfvlpsgell yftaavcvly
      241 dpaagtqrhy rghtddiksl avhpdsvtia sgqvagnsqd gkalpphvri whsvslctlh
      301 vigvgsfera vtclsfsktd ggsllcacde sgdhvlsvwq wqrenkitev kcstepvlat
      361 ifhptepnli itcgksqlyy wslegttggg ttsggatlsk rqgvfekhek prfvlcvafa
      421 engdvvtgds ngnlyvwgkg shrishavsn ahdgsifalc vcrdgtllsg ggkdgrvilw
      481 grdykkvqet ripecfgpvr tiaegrgggt lyvgttkncv msgnlesgls cliqghtdel
      541 wglcthptld lfltcghdkf vhlwnskehq pvwsttleda arvagfhpsg svvavgtssg
      601 rflvldsqth vivtsvsdaa eqisvtsysp dghylavgsh dnfiylyeva eegreyrrvg
      661 kctghssfvt hldwasdsss fmtnsgdyei lywdpdsckq ivsaenvrni dwenssctlg
      721 fyvlgiwpdg adgtdinavt rshdrkqlat gddfggvrly nypcvvprap shkysghssh
      781 vtrvvflhnd svllsaggkd stvlqwavl
//
LOCUS       NP_001125616             266 aa            linear   PRI 19-JUN-2025
DEFINITION  non-structural maintenance of chromosomes element 1 homolog [Pongo
            abelii].
ACCESSION   NP_001125616
VERSION     NP_001125616.1
DBSOURCE    REFSEQ: accession NM_001132144.1
KEYWORDS    RefSeq.
SOURCE      Pongo abelii (Sumatran orangutan)
  ORGANISM  Pongo abelii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Pongo.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CR858866.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR858866.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA2058385,
                                           SAMN07839603 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Pongo abelii"
                     /db_xref="taxon:9601"
                     /chromosome="18"
                     /map="18"
     Protein         1..266
                     /product="non-structural maintenance of chromosomes
                     element 1 homolog"
                     /EC_number="2.3.2.27"
                     /note="non-SMC element 1 homolog; NSE1 homolog, SMC5-SMC6
                     complex component"
                     /calculated_mol_wt=30769
     Region          1..102
                     /region_name="Interaction with NSMCE3.
                     /evidence=ECO:0000250|UniProtKB:Q8WV22"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5RAZ5.1)"
     Region          16..175
                     /region_name="SMC_Nse1"
                     /note="Nse1 non-SMC component of SMC5-6 complex;
                     pfam07574"
                     /db_xref="CDD:462214"
     Region          189..235
                     /region_name="RING-CH-C4HC3_NSE1"
                     /note="RING-CH finger, H2 subclass (C4HC3-type), found in
                     non-structural maintenance of chromosomes (SMC) element 1
                     homolog (NSE1) and similar proteins; cd16493"
                     /db_xref="CDD:438156"
     Region          245..266
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5RAZ5.1)"
     Site            251
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WV22; propagated from
                     UniProtKB/Swiss-Prot (Q5RAZ5.1)"
     CDS             1..266
                     /gene="NSMCE1"
                     /coded_by="NM_001132144.1:43..843"
                     /db_xref="GeneID:100172534"
ORIGIN      
        1 mqgstrrmsv mtdvhrrflq llmthgvlee wdvkrlqrhc ykvhdrnatv dkledfinni
       61 nsvleslyie ikrgvteddg rpiyalvnla ttsiskmatd faeneldlfr kaleliidse
      121 tgfgsstnil nlvdqlkgkk mrkkeaeqvl qkfvqnkwli ekegeftlhg railemeqyi
      181 retypdavki cnichslliq gqscetcgir mhlpcvakyf qsnaeprcph cndywpheip
      241 kvfdpekere sgvsksnkks lrsrqh
//
LOCUS       NP_001281141             177 aa            linear   VRT 19-JUN-2025
DEFINITION  ferritin, heavy polypeptide-like 27 [Cynoglossus semilaevis].
ACCESSION   NP_001281141 XP_008328898
VERSION     NP_001281141.1
DBSOURCE    REFSEQ: accession NM_001294212.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 177)
  AUTHORS   Wang,W., Zhang,M. and Sun,L.
  TITLE     Ferritin M of Cynoglossus semilaevis: an iron-binding protein and a
            broad-spectrum antimicrobial that depends on the integrity of the
            ferroxidase center and nucleation center for biological activity
  JOURNAL   Fish Shellfish Immunol 31 (2), 269-274 (2011)
   PUBMED   21651984
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from HQ913639.1.
            
            On Jun 26, 2014 this sequence version replaced XP_008328898.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HQ913639.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01766803, SAMN03753712
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..177
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="17"
                     /map="17"
     Protein         1..177
                     /product="ferritin, heavy polypeptide-like 27"
                     /EC_number="1.16.3.1"
                     /note="ferritin M subunit; ferritin, middle subunit"
                     /calculated_mol_wt=20561
     Region          10..170
                     /region_name="Euk_Ferritin"
                     /note="eukaryotic ferritins; cd01056"
                     /db_xref="CDD:153114"
     Site            order(24,31,58..59,62,104,138)
                     /site_type="other"
                     /note="ferroxidase diiron center [ion binding]"
                     /db_xref="CDD:153114"
     Site            order(54,57..58,61)
                     /site_type="active"
                     /note="ferrihydrite nucleation center [active]"
                     /db_xref="CDD:153114"
     Site            order(115,128,131)
                     /site_type="active"
                     /note="iron ion channel [active]"
                     /db_xref="CDD:153114"
     CDS             1..177
                     /gene="fthl27"
                     /gene_synonym="FerM"
                     /coded_by="NM_001294212.1:1..534"
                     /db_xref="GeneID:103393642"
ORIGIN      
        1 mesqvrqnyh rdceaavnrm inmelfasyn ytsmafhfsr ddvalpgfah ffkensheer
       61 ehaekllsfq nkrggriflq dikkperdew vngldameha lqlektvnqa lldlhklase
      121 hgdphmcdfl ethylneqve aikklgdyit nlkrldpann kmaeylfdkh tlhggks
//
LOCUS       NP_001306746             551 aa            linear   VRT 19-JUN-2025
DEFINITION  ATP synthase F(1) complex subunit alpha, mitochondrial [Cynoglossus
            semilaevis].
ACCESSION   NP_001306746 XP_008324506
VERSION     NP_001306746.1
DBSOURCE    REFSEQ: accession NM_001319817.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KJ813813.1.
            
            On Feb 4, 2016 this sequence version replaced XP_008324506.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KJ813813.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN08193245, SAMN08493827
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="14"
                     /map="14"
     Protein         1..551
                     /product="ATP synthase F(1) complex subunit alpha,
                     mitochondrial"
                     /note="mitochondrial ATP synthase subunit alpha"
                     /calculated_mol_wt=59691
     Region          48..550
                     /region_name="AtpA"
                     /note="FoF1-type ATP synthase, alpha subunit [Energy
                     production and conversion]; COG0056"
                     /db_xref="CDD:439826"
     CDS             1..551
                     /gene="atp5fa1"
                     /coded_by="NM_001319817.1:1..1656"
                     /db_xref="GeneID:103390430"
ORIGIN      
        1 mlsvrvastl vrtlprragf vsknvaaacv gvknlhtsrp wlqktgtaev ssileekimg
       61 adtsaeleet grvlsigdgi arvyglrnvq aeemvefssg lkgmslnlep dnvgvvvfgn
      121 dklikegdiv krtgaivdvp vgeellgrvv dalgnaidgk gplgssirrr vglkapgiip
      181 risvrepmqt gikavdslvp igrgqrelii gdrqtgktai aidtiinqkr fnegtdekkk
      241 lyciyvaigq krstvaqlvk rltdtdamky tivvsatasd aaplqylapy agcsmgeyfr
      301 dngkhaliiy ddlskhavay rqmslllrrp pgreaypgdv fylhsrller aakmndnfgg
      361 gsltalpvie tqagdvsayi ptnvisitdg qifletelfy kgirpainvg lsvsrvgsaa
      421 qtramkqvag tmklelaqyr evaafaqfgs dldaatqqll nrgvrltell kqgqyapmai
      481 eeqvtviyag vrgyldkmep skitkfekaf lqhilsqqqd llaaikadgk iseasdaklk
      541 qvvlnflssf e
//
LOCUS       NP_001428423             761 aa            linear   ROD 19-JUN-2025
DEFINITION  transmembrane channel-like protein 1 isoform 1 [Mus musculus].
ACCESSION   NP_001428423
VERSION     NP_001428423.1
DBSOURCE    REFSEQ: accession NM_001441494.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 761)
  AUTHORS   Beurg,M., Konrad,D.E. and Fettiplace,R.
  TITLE     Hair cell apoptosis and deafness in Tmc1 mutations
  JOURNAL   Proc Natl Acad Sci U S A 122 (12), e2425215122 (2025)
   PUBMED   40100636
REFERENCE   2  (residues 1 to 761)
  AUTHORS   Wang,P., Miller,K.K., He,E., Dhawan,S.S., Cunningham,C.L. and
            Grillet,N.
  TITLE     LOXHD1 is indispensable for maintaining TMC1 auditory
            mechanosensitive channels at the site of force transmission
  JOURNAL   Nat Commun 15 (1), 7865 (2024)
   PUBMED   39256406
  REMARK    Erratum:[Nat Commun. 2024 Oct 15;15(1):8878. doi:
            10.1038/s41467-024-52972-5. PMID: 39406713]
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 761)
  AUTHORS   Harmon,T.C., Madlon-Kay,S., Pearson,J. and Mooney,R.
  TITLE     Vocalization modulates the mouse auditory cortex even in the
            absence of hearing
  JOURNAL   Cell Rep 43 (8), 114611 (2024)
   PUBMED   39116205
REFERENCE   4  (residues 1 to 761)
  AUTHORS   Lee,J.H., Perez-Flores,M.C., Park,S., Kim,H.J., Chen,Y., Kang,M.,
            Kersigo,J., Choi,J., Thai,P.N., Woltz,R.L., Perez-Flores,D.C.,
            Perkins,G., Sihn,C.R., Trinh,P., Zhang,X.D., Sirish,P., Dong,Y.,
            Feng,W.W., Pessah,I.N., Dixon,R.E., Sokolowski,B., Fritzsch,B.,
            Chiamvimonvat,N. and Yamoah,E.N.
  TITLE     The Piezo channel is a mechano-sensitive complex component in the
            mammalian inner ear hair cell
  JOURNAL   Nat Commun 15 (1), 526 (2024)
   PUBMED   38228630
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 761)
  AUTHORS   Beurg,M., Schwalbach,E.T. and Fettiplace,R.
  TITLE     LHFPL5 is a key element in force transmission from the tip link to
            the hair cell mechanotransducer channel
  JOURNAL   Proc Natl Acad Sci U S A 121 (3), e2318270121 (2024)
   PUBMED   38194445
REFERENCE   6  (residues 1 to 761)
  AUTHORS   Webster,D.B.
  TITLE     Degeneration followed by partial regeneration of the organ of Corti
            in deafness (dn/dn) mice
  JOURNAL   Exp Neurol 115 (1), 27-31 (1992)
   PUBMED   1728569
REFERENCE   7  (residues 1 to 761)
  AUTHORS   Horner,K.C., Lenoir,M. and Bock,G.R.
  TITLE     Distortion product otoacoustic emissions in hearing-impaired mutant
            mice
  JOURNAL   J Acoust Soc Am 78 (5), 1603-1611 (1985)
   PUBMED   4067076
REFERENCE   8  (residues 1 to 761)
  AUTHORS   Steel,K.P. and Bock,G.R.
  TITLE     Electrically-evoked responses in animals with progressive spiral
            ganglion degeneration
  JOURNAL   Hear Res 15 (1), 59-67 (1984)
   PUBMED   6541219
REFERENCE   9  (residues 1 to 761)
  AUTHORS   Pujol,R., Shnerson,A., Lenoir,M. and Deol,M.S.
  TITLE     Early degeneration of sensory and ganglion cells in the inner ear
            of mice with uncomplicated genetic deafness (dn): preliminary
            observations
  JOURNAL   Hear Res 12 (1), 57-63 (1983)
   PUBMED   6662828
REFERENCE   10 (residues 1 to 761)
  AUTHORS   Bock,G.R., Frank,M.P. and Steel,K.P.
  TITLE     Preservation of central auditory function in the deafness mouse
  JOURNAL   Brain Res 239 (2), 608-612 (1982)
   PUBMED   7093705
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC102790.7 and AC162458.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: LC566569.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849374,
                                           SAMN00849377 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 13.98 cM"
     Protein         1..761
                     /product="transmembrane channel-like protein 1 isoform 1"
                     /note="transmembrane, cochlear expressed 1; transmembrane
                     channel-like protein 1; deafness protein; transmembrane
                     cochlear-expressed protein 1"
                     /calculated_mol_wt=87570
     CDS             1..761
                     /gene="Tmc1"
                     /gene_synonym="4933416G09Rik; Beethoven; Bth; CWEA1; dn;
                     TMC1ex1"
                     /coded_by="NM_001441494.1:103..2388"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:13409"
                     /db_xref="MGI:MGI:2151016"
ORIGIN      
        1 mppkkvqiqv eekeedtees sseeeedklp rreslrpkrk rtrdvinedd pepepedeet
       61 rkarekerrr rlrrgaeeee eideeelerl kalldenrqm iatvkckpwk mekkievlke
      121 akkfvseneg algkgkgkkw fafkmmmakk wakflrdfen fkaacvpwen kikaiesqfg
      181 ssvasyflfl rwmygvnmvl fvltfsliml peylwglpyg slprktvpra eeasaanfgv
      241 lydfnglaqy svlfygyydn krtigwlnfr lplsyflvgi mcigysflvv lkamtknigd
      301 dgggddntfn fswkvfcswd ylignpetad nkfnsitmnf keaiieeraa qveenihlir
      361 flrflanffv fltlgasgyl ifwavkrsqe faqqdpdtlg wweknemnmv msllgmfcpt
      421 lfdlfaeled yhplialkwl lgrifalllg nlyvfilalm deinnkieee klvkanitlw
      481 eanmikayne slsglsgntt gapffvhpad vprgpcwetm vgqefvrltv sdvlttyvti
      541 ligdflracf vrfcnycwcw dleygypsyt efdisgnvla lifnqgmiwm gsffapslpg
      601 inilrlhtsm yfqcwavmcc nvpearvfka srsnnfylgm lllilflstm pvlymivslp
      661 psfdcgpfsg knrmfevige tlehdfpswm akilrqlsnp glviavilvm vltiyylnat
      721 akgqkaanld lkkkmkqqal enkmrnkkma aaraaaaagg q
//
LOCUS       NP_001281126             633 aa            linear   VRT 19-JUN-2025
DEFINITION  growth hormone receptor a precursor [Cynoglossus semilaevis].
ACCESSION   NP_001281126
VERSION     NP_001281126.1
DBSOURCE    REFSEQ: accession NM_001294197.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 633)
  AUTHORS   Ma,Q., Liu,S.F., Zhuang,Z.M., Sun,Z.Z., Liu,C.L. and Tang,Q.S.
  TITLE     The co-existence of two growth hormone receptors and their
            differential expression profiles between female and male tongue
            sole (Cynoglossus semilaevis)
  JOURNAL   Gene 511 (2), 341-352 (2012)
   PUBMED   23026213
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from HQ334200.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HQ334200.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN04556680
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="Z"
                     /map="Z"
     Protein         1..633
                     /product="growth hormone receptor a precursor"
                     /note="growth hormone receptor 1"
                     /calculated_mol_wt=67799
     sig_peptide     1..28
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2935
     Region          43..>115
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cl21522"
                     /db_xref="CDD:473895"
     Region          142..226
                     /region_name="FN3"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; cd00063"
                     /db_xref="CDD:238020"
     Region          305..595
                     /region_name="GHBP"
                     /note="Growth hormone receptor binding; pfam12772"
                     /db_xref="CDD:463696"
     CDS             1..633
                     /gene="ghra"
                     /gene_synonym="ghr"
                     /coded_by="NM_001294197.1:166..2067"
                     /db_xref="GeneID:103397680"
ORIGIN      
        1 maihslschl lllllmssld glikpgsafi hdwdqrassv tlephitgcl srdqetfrcw
       61 wspgnfqnls ssgalrffyl kkespnsqwk ecphyiysnr ecffnmtyts vwitycmqlr
      121 gennvtfyne ndcfsvediv rpdppvnlnw tvlsispsgv sfdvrvkwep ppsadmatgw
      181 irvhyelqyr ernttkweal emqpqhqqti fglhigkkye vhircrmigf kkfgelsdsi
      241 fievsevest ettfsftivv vfgivgilil vmliivsqqh rfmkillppv papkikgina
      301 emlkkgklee lnlilsgggm gglppfaadf yqdepwvefi evdaedtdsg ekedhqgldt
      361 qrllglpqpi nqpmnigcan tisfpdddsg rascydpdll dqdtpvlvtt llpgqpenge
      421 alldvvggts tperserplv qiqttgpqtw vntdfyaqvs nvmpsggvvl spgqqlrtqe
      481 stssteqeet qkrekdsege ekkeqqfelv vvdpeghgna tesiaqqalt tpvspipgeg
      541 yqtiqpqqve trqaaasedn qspyvgpefp maqfsvpvsd ytivqevdtq hslllhppph
      601 qspppclpqp ppkslfgmpv gyitpdllgn lsp
//
LOCUS       NP_001015771             659 aa            linear   VRT 19-JUN-2025
DEFINITION  echinoderm microtubule-associated protein-like 2 isoform 1 [Xenopus
            tropicalis].
ACCESSION   NP_001015771
VERSION     NP_001015771.1
DBSOURCE    REFSEQ: accession NM_001015771.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (residues 1 to 659)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC089711.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089711.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Xenopus tropicalis"
                     /db_xref="taxon:8364"
                     /chromosome="8"
                     /map="8"
     Protein         1..659
                     /product="echinoderm microtubule-associated protein-like 2
                     isoform 1"
                     /note="echinoderm microtubule associated protein like 1"
                     /calculated_mol_wt=71780
     Region          21..92
                     /region_name="HELP"
                     /note="HELP motif; pfam03451"
                     /db_xref="CDD:460922"
     Region          107..153
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          162..204
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          181..547
                     /region_name="WD40"
                     /note="WD40 repeat [General function prediction only];
                     COG2319"
                     /db_xref="CDD:441893"
     Region          211..256
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          264..296
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          307..344
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          349..385
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          391..426
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          433..465
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          473..513
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          519..543
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          586..625
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     CDS             1..659
                     /gene="eml1"
                     /coded_by="NM_001015771.1:12..1991"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:548488"
                     /db_xref="Xenbase:XB-GENE-949779"
ORIGIN      
        1 mkktsskskq vvfypeegvv klylrgrsvp lyvpdslvas ysldakgelp trelqlewvy
       61 gyrgrdcrsn lfvlpsgell yftaavcvly dpaagtqrhy rghtddiksl avhpdsvtia
      121 sgqvagnsqd gkalpphvri whsvslctlh vigvgsfera vtclsfsktd ggsllcacde
      181 sgdhvlsvwq wqrenkitev kcstepvlat ifhptepnli itcgksqlyy wslegttggg
      241 ttsggatlsk rqgvfekhek prfvlcvafa engdvvtgds ngnlyvwgkg shrishavsn
      301 ahdgsifalc vcrdgtllsg ggkdgrvilw grdykkvqet ripecfgpvr tiaegrgggt
      361 lyvgttkncv msgnlesgls cliqghtdel wglcthptld lfltcghdkf vhlwnskehq
      421 pvwsttleda arvagfhpsg svvavgtssg rflvldsqth vivtsvsdaa eqisvtsysp
      481 dghylavgsh dnfiylyeva eegreyrrvg kctghssfvt hldwasdsss fmtnsgdyei
      541 lywdpdsckq ivsaenvrni dwenssctlg fyvlgiwpdg adgtdinavt rshdrkqlat
      601 gddfggvrly nypcvvprap shkysghssh vtrvvflhnd svllsaggkd stvlqwavl
//
LOCUS       NP_001281137             509 aa            linear   VRT 19-JUN-2025
DEFINITION  steroid 17-alpha-hydroxylase/17,20 lyase [Cynoglossus semilaevis].
ACCESSION   NP_001281137
VERSION     NP_001281137.1
DBSOURCE    REFSEQ: accession NM_001294208.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 509)
  AUTHORS   Chen,C.F., Wen,H.S., Wang,Z.P., He,F., Zhang,J.R., Chen,X.Y.,
            Jin,G.X., Shi,B., Shi,D., Yang,Y.P., Li,J.F., Qi,B.X. and Li,N.
  TITLE     Cloning and expression of P450c17-I
            (17alpha-hydroxylase/17,20-lyase) in brain and ovary during gonad
            development in Cynoglossus semilaevis
  JOURNAL   Fish Physiol Biochem 36 (4), 1001-1012 (2010)
   PUBMED   20069358
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from GU338001.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GU338001.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06859058 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="12"
                     /map="12"
     Protein         1..509
                     /product="steroid 17-alpha-hydroxylase/17,20 lyase"
                     /note="cytochrome P450c17-I; cytochrome P450c17Ib"
                     /calculated_mol_wt=56339
     Region          59..493
                     /region_name="CYP17A1"
                     /note="cytochrome P450 family 17, subfamily A, polypeptide
                     1; cd20673"
                     /db_xref="CDD:410766"
     Site            order(85,95,111..112,120,124,300..301,304..305,308..309,
                     312,368,372,375,436..438,442..446,450)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:410766"
     Site            order(104,112..113,202..203,206..207,210,240,299..300,
                     303..304,307..308,368..369,373,444,484..485)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:410766"
     CDS             1..509
                     /gene="cyp17a1"
                     /gene_synonym="cyp17I"
                     /coded_by="NM_001294208.1:14..1543"
                     /db_xref="GeneID:103387725"
ORIGIN      
        1 mclpvfftsf ttlavvalgl kpqpqepphl pslpligsll slwsplapyi lfkqlqrkyg
       61 hiyslkmgsh hvvvvnhykd akevllkkgk tfagrprtvt tdiltrdgkd iafgnfsatw
      121 kfhrkivhga lcmfgessvs iekiicaeak tlcsvlseaa saghsldlsp eltravtnvi
      181 cflcfnssys rgdpefetml eysqgivdpv akdslvdifp wlqifpnagl rllrkcgstr
      241 dallqkkydq hkvdysdhvq rdlldallra krsaennnta eirdesvgls ddhilmtvgd
      301 ifgagvettt tvlkwaiiyl lhypqvqrli qeeldtkvgs grspklsdrg nlpyleatir
      361 evlrirpvap lliphvalsd tslgdfairk gsrviinlws lhhdenewkn pelfdpgrfi
      421 dskgtglilp sssylpfgag irvclgeala kmelflflsw ilqhftlsvp pgdelpsleg
      481 kfgvvlqpak ykvtatprqg gainegetl
//
LOCUS       NP_001124606             486 aa            linear   PRI 19-JUN-2025
DEFINITION  tRNA (uracil-5-)-methyltransferase homolog B [Pongo abelii].
ACCESSION   NP_001124606
VERSION     NP_001124606.1
DBSOURCE    REFSEQ: accession NM_001131134.1
KEYWORDS    RefSeq.
SOURCE      Pongo abelii (Sumatran orangutan)
  ORGANISM  Pongo abelii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Pongo.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CR857127.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR857127.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN10521808 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Pongo abelii"
                     /db_xref="taxon:9601"
                     /chromosome="X"
                     /map="X"
     Protein         1..486
                     /product="tRNA (uracil-5-)-methyltransferase homolog B"
                     /EC_number="2.1.1.35"
                     /note="tRNA (uracil-5-)-methyltransferase homolog;
                     Putative methyltransferase CXorf34 homolog; TRM2 homolog;
                     tRNA (uracil(54)-C(5))-methyltransferase homolog; TRM2
                     homolog B; rRNA (uracil-5-)-methyltransferase TRMT2B; tRNA
                     methyltransferase 2 homolog B"
                     /calculated_mol_wt=54419
     Region          <76..485
                     /region_name="TrmA"
                     /note="tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD
                     family [Translation, ribosomal structure and biogenesis];
                     COG2265"
                     /db_xref="CDD:441866"
     CDS             1..486
                     /gene="TRMT2B"
                     /gene_synonym="CXorf34"
                     /coded_by="NM_001131134.1:405..1865"
                     /db_xref="GeneID:100171443"
ORIGIN      
        1 maglffkpgl lpwyarnppg wsqlflgtvc kgdftrviat kcqkgqksqk kpshlgpldg
       61 swqerladvv tplwrlsyee qlkvkfaaqk kilqrlesyi qmlngvsvtt avpkserlsc
      121 llhpiipspv ingyrnkstf svnrgpdgnp ktvgfylgtw rdgnmvcvqs nhlknipekh
      181 sqvaqyyevf lrqsplepcl vfheggywre ltvrtnsqgh tmaiitfhpq nlsqeefhvq
      241 keivkeffir gpgaacdlts lyfqestmtr cshqqspyql lfgepyifee llslkirisp
      301 daffqintag aemlyrtvge ltgvnsdtil ldiccgtgvi glslsqhtsr vlgielveqa
      361 vedarwtaaf ngitnsefht graekilpgl lkskedgqsi vavvnparag lhykviqair
      421 nfraihtlvf vscklhgest rnvielccpp dpakkllgep fvlqqvvpvd lfphtphcel
      481 vllftr
//
LOCUS       NP_001348133             387 aa            linear   VRT 19-JUN-2025
DEFINITION  growth/differentiation factor 10b precursor [Scleropages formosus].
ACCESSION   NP_001348133 XP_018604991
VERSION     NP_001348133.1
DBSOURCE    REFSEQ: accession NM_001361204.1
KEYWORDS    RefSeq.
SOURCE      Scleropages formosus (Asian bonytongue)
  ORGANISM  Scleropages formosus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
            Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from LR584069.1.
            
            On Mar 7, 2018 this sequence version replaced XP_018604991.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN05880667,
                              SAMN05880668 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Scleropages formosus"
                     /db_xref="taxon:113540"
                     /chromosome="4"
                     /map="4"
     Protein         1..387
                     /product="growth/differentiation factor 10b precursor"
                     /calculated_mol_wt=40145
     sig_peptide     1..24
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2368
     Region          18..108
                     /region_name="Tissue_fac"
                     /note="Tissue factor; pfam01108"
                     /db_xref="CDD:460067"
     CDS             1..387
                     /gene="ifngr1l"
                     /coded_by="NM_001361204.1:166..1329"
                     /db_xref="GeneID:108932840"
ORIGIN      
        1 maaraealla lllllgvsta svlailppvn vtvkcknfen vlywnysasa lpayfnvnvy
       61 ryvsssphtv gscsnttqhy cdisvetrev eehyyatvta tvgsnvssea dstqftyynl
      121 fdghlcavdf ppvnvsfeed kmvlsfqhpf rfyrktlkhv knkgeykkfh fyikygnest
      181 hqtftcdlrs iceeeilikd gvqvvhlwgq mntmnlstsk eivvnlprke rnslmmlyli
      241 paiitlvlli ggigfpiyrk lthsstsipk amasllstsp rgasilsper pntvvvvqst
      301 dspssetfll pdgdcppvdg apkdgsrfpi gvgidkdtsa gsggsgseae sseanrsvsq
      361 afvsgydrpk qlgvemapgd tvfgyrd
//
LOCUS       NP_001281150             663 aa            linear   VRT 19-JUN-2025
DEFINITION  putative ATP-dependent RNA helicase DDX4 [Cynoglossus semilaevis].
ACCESSION   NP_001281150
VERSION     NP_001281150.1
DBSOURCE    REFSEQ: accession NM_001294221.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 663)
  AUTHORS   Wang,Z., Gao,J., Song,H., Wu,X., Sun,Y., Qi,J., Yu,H., Wang,Z. and
            Zhang,Q.
  TITLE     Sexually dimorphic expression of vasa isoforms in the tongue sole
            (Cynoglossus semilaevis)
  JOURNAL   PLoS One 9 (3), e93380 (2014)
   PUBMED   24671276
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KF856012.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KF856012.1, HQ727561.2 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMN00752404, SAMN03753710
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="14"
                     /map="14"
     Protein         1..663
                     /product="putative ATP-dependent RNA helicase DDX4"
                     /EC_number="3.6.4.13"
                     /note="ATP dependent RNA helicase; DEAD-box helicase 4"
                     /calculated_mol_wt=72736
     Region          178..441
                     /region_name="DEADc_DDX4"
                     /note="DEAD-box helicase domain of DEAD box protein 4;
                     cd18052"
                     /db_xref="CDD:350810"
     Site            order(200,210,222,240,242..244,247,265..271,378..379,414)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:350810"
     Site            order(305..307,333..334,354..357,360,382,388)
                     /site_type="other"
                     /note="RNA binding site [nucleotide binding]"
                     /db_xref="CDD:350810"
     Region          447..576
                     /region_name="SF2_C_DEAD"
                     /note="C-terminal helicase domain of the DEAD box
                     helicases; cd18787"
                     /db_xref="CDD:350174"
     Site            order(535,537,562,565..566)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:350174"
     CDS             1..663
                     /gene="ddx4"
                     /gene_synonym="vas-l; vas-m; vas-s; vasa"
                     /coded_by="NM_001294221.1:69..2060"
                     /db_xref="GeneID:103389588"
ORIGIN      
        1 mddweetena evvsvtscas tegsrehfwk ddssgkrade ksngtgtitg tssfnqdwef
       61 fkntegqqgg irgrgrgrgf grenrsdfng dsngfcesef rgvsrgghgg rggrgrgfrr
      121 gteggsrggf redgeqrgrg gfrggyrgkg ennffqeken kelkqrdegs adkpkvsyip
      181 palaedensv fahyetginf dkyddilvnv sgtnppqaim tfeeaalcds lsknvsrsgy
      241 vkptpvqkhg ipiisagrdl macaqtgsgk taafllpilh qlmiggasss ffselqepka
      301 iivaptreli nqiflearkf aygtvvrpvv vyggvsirhq vsdlnkgcnv lcgtpgrlmd
      361 miergkvgls kvqyfvldea drmldmgfep dmrrlvaspg mpsregrqtl mfsatfpeei
      421 qklaadflkp dylflavgiv ggacsdveqt fievgkfskr eqlldlvktc gnertivfve
      481 kkrqadfiat flcqenvptt sihgdreqwq reqaladfky gkcpvlvats vaargldipd
      541 vqhvvnfdlp gsideyvhri grtgrcgnvg ravsffdtdv dghlsrplis ilskaqqevp
      601 pwleqlafss assggnfnan knnfaftdsr kgqqrgssfq gntvqsqvta vlqpppeeee
      661 ewe
//
LOCUS       NP_001315182             734 aa            linear   VRT 19-JUN-2025
DEFINITION  relaxin receptor 2a [Cynoglossus semilaevis].
ACCESSION   NP_001315182 XP_016896940
VERSION     NP_001315182.1
DBSOURCE    REFSEQ: accession NM_001328253.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KP749830.1.
            
            On Jun 9, 2016 this sequence version replaced XP_016896940.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KP749830.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMN08493838 [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="19"
                     /map="19"
     Protein         1..734
                     /product="relaxin receptor 2a"
                     /note="leucine-rich repeat-containing G protein coupled
                     receptor 8; relaxin/insulin like family peptide receptor
                     2; relaxin family peptide receptor 2"
                     /calculated_mol_wt=83282
     Region          19..54
                     /region_name="LDLa"
                     /note="Low Density Lipoprotein Receptor Class A domain, a
                     cysteine-rich repeat that plays a central role in
                     mammalian cholesterol metabolism; the receptor protein
                     binds LDL and transports it into cells by endocytosis; 7
                     successive cysteine-rich repeats of about...; cd00112"
                     /db_xref="CDD:238060"
     Site            order(24,33,44..45)
                     /site_type="active"
                     /note="putative binding surface [active]"
                     /db_xref="CDD:238060"
     Site            order(37,40,44,50..51)
                     /site_type="other"
                     /note="calcium-binding site [ion binding]"
                     /db_xref="CDD:238060"
     Site            47..51
                     /site_type="other"
                     /note="D-X-S-D-E motif"
                     /db_xref="CDD:238060"
     Region          <113..>346
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          115..138
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          139..162
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          163..186
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          187..210
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          211..235
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          236..259
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          260..283
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          284..307
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          309..332
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          333..351
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          394..680
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          396..420
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410628"
     Region          429..450
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410628"
     Region          474..496
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410628"
     Region          518..534
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410628"
     Region          566..589
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:410628"
     Region          615..637
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:410628"
     Region          648..673
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:410628"
     CDS             1..734
                     /gene="rxfp2a"
                     /gene_synonym="LGR8; rxfp2"
                     /coded_by="NM_001328253.1:273..2477"
                     /db_xref="GeneID:103395234"
ORIGIN      
        1 mslplsmsls skveaevrcp lgqfpcgnls eclpqalqcn ghkdcpngad errcgdnigw
       61 adivgetlen tnpvdqysgd ecflqeypds cdciqtevvc vevnlqnvpp lspnvtwlsl
      121 ranriqvltd fvfseypalq rlflqnnslq fisrhafrgl hklkrlflsd nlisslspgv
      181 fgdlhqlewl mldnnplril aqdtfiglqs lvylsmvgts leqlphpsfc qhmpsldwld
      241 legnqiqtln ysllntcskl rvlflmdnmi krvpentfls lwkltelnls snrirelpkn
      301 tfkslsnsll rlnvshnpll qiqpshfnhl tqlqslaleg ieipdiqtkm flpmknlshi
      361 yfkkfqycsy aphvrsckpn tdgissfedl lanvvlrvsv wviafitcfg nlfvigmrsl
      421 iraennlhaa cikvlccadc lmgvylffvg vfdvkfrgqy nrnallwmes vecrtigfla
      481 mlssevsvll ltyltlekfl vivfpfsnlr pgklqtgvvl asiwvlgfii aavplmneev
      541 fgnyygrngv cfplhsdrqe kptakgystg iflglnvvaf lvivfsyfsm fysiyktgin
      601 atdlrsrlhr dvavanrfff ivfsdalcwi piflvkilsl lkveipgtis swvvifilpi
      661 nsalnpilyt lttsffreqv evllcrwqrr hilkkdrksl tsstifmeas rpqcyqqpay
      721 lqrisltgad prya
//
LOCUS       NP_001281167             269 aa            linear   VRT 19-JUN-2025
DEFINITION  interferon regulatory factor 1b [Cynoglossus semilaevis].
ACCESSION   NP_001281167
VERSION     NP_001281167.1
DBSOURCE    REFSEQ: accession NM_001294238.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 269)
  AUTHORS   Lu,Y., Wang,Q., Liu,Y., Shao,C., Chen,S. and Sha,Z.
  TITLE     Gene cloning and expression analysis of IRF1 in half-smooth tongue
            sole (Cynoglossus semilaevis)
  JOURNAL   Mol Biol Rep 41 (6), 4093-4101 (2014)
   PUBMED   24584575
  REMARK    GeneRIF: These results suggested that CsIRF1 gene might involve in
            not only antiviral activity but also antibacterial procedure,
            indicating its vital role in Cynoglossus semilaevis innate defense
            system.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from JF930152.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: JF930152.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN08493835 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="19"
                     /map="19"
     Protein         1..269
                     /product="interferon regulatory factor 1b"
                     /note="interferon regulatory factor 1"
                     /calculated_mol_wt=31251
     Region          7..111
                     /region_name="IRF"
                     /note="Interferon regulatory factor transcription factor;
                     pfam00605"
                     /db_xref="CDD:459863"
     Site            order(40,79,81..82,85)
                     /site_type="other"
                     /note="DNA sequence recognition sites [nucleotide
                     binding]"
                     /db_xref="CDD:238051"
     Site            order(84..85,87,90)
                     /site_type="metal-binding"
                     /db_xref="CDD:238051"
     CDS             1..269
                     /gene="irf1b"
                     /gene_synonym="irf1"
                     /coded_by="NM_001294238.1:105..914"
                     /db_xref="GeneID:103394766"
ORIGIN      
        1 mpvtrmrmrp wlekmidskc isgltwmdke rtmfsipwkh aarhgwemdk daclfkkwai
       61 htgkyiegqa cdpktwkanf rcamnslpdi eevkdksvnk gqqamrifrm lpvsgksrdr
      121 rrkakvklsk knstdkteed tdysdtqspq stspseepaf dvkdmlqrht ievgpwngdm
      181 eydsddittn nfevlapycn rfqlspphrh dysenilenf qhyldqqdms lsslftdqss
      241 sdetdenvny tildnvqpsl tvnpwsdvf
//
LOCUS       NP_001120622             469 aa            linear   VRT 19-JUN-2025
DEFINITION  aldehyde dehydrogenase family 3 member B1 [Xenopus tropicalis].
ACCESSION   NP_001120622
VERSION     NP_001120622.1
DBSOURCE    REFSEQ: accession NM_001127150.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (residues 1 to 469)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC161766.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161766.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Xenopus tropicalis"
                     /db_xref="taxon:8364"
                     /chromosome="3"
                     /map="3"
     Protein         1..469
                     /product="aldehyde dehydrogenase family 3 member B1"
                     /EC_number="1.2.1.5"
                     /note="aldehyde dehydrogenase 3 family member B2"
                     /calculated_mol_wt=52132
     Region          5..447
                     /region_name="ALDH_F3AB"
                     /note="Aldehyde dehydrogenase family 3 members A1, A2, and
                     B1 and related proteins; cd07132"
                     /db_xref="CDD:143450"
     Site            order(57,87..88,92,99,103,105,180,182,190,194,197,204,224,
                     227,230..231,234,271,281,359..360,364,369,375,378,
                     381..390,396,401,404..405,407,410,424,426..427,429..433,
                     437,439..440,442..446)
                     /site_type="other"
                     /note="homodimeric interface [polypeptide binding]"
                     /db_xref="CDD:143450"
     Site            order(113..115,141,170,188,287,289..290,293,334,336)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:143450"
     Site            order(115,210,241,244)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143450"
     CDS             1..469
                     /gene="aldh3b1"
                     /gene_synonym="aldh3b2; aldh8"
                     /coded_by="NM_001127150.1:13..1422"
                     /db_xref="GeneID:100145787"
                     /db_xref="Xenbase:XB-GENE-5776192"
ORIGIN      
        1 mepqeetlrr lrssflagrt rgakfrfaql ealarfleen kkeisqslkm dlskpqfete
       61 lselslvrse inlalsslga wmkdefvakn lattfdtafi rkdpfgvvli igpwnypvhl
      121 tllplvgaia agncviikps eisqnterll aehlpryldk dcfavlcaga edtsrllenk
      181 fdyifftgna hvgkivmaaa akhltpvtle lggknpcyvd eecdisnaar riswsryfna
      241 gqtclapdyv lctertrdrl vkalkatvre fygqdpkqsp dlgriindrh frrvsallss
      301 gtivtggqtd eaekyiapti lidvkesdpv mqeeifgpvl pvmtigglda alefinkrer
      361 plaayvyssk sqvvdrfleg tssggfcand gllhstlisl pfggighsgm gkyhgkfsfd
      421 tfshhracll rsdgreklne iryppyteqh lgmavyamev kkgwscslq
//
LOCUS       NP_005078                621 aa            linear   PRI 19-JUN-2025
DEFINITION  RNA-binding protein FXR1 isoform a [Homo sapiens].
ACCESSION   NP_005078
VERSION     NP_005078.2
DBSOURCE    REFSEQ: accession NM_005087.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 621)
  AUTHORS   Khoroshkin,M., Buyan,A., Dodel,M., Navickas,A., Yu,J., Trejo,F.,
            Doty,A., Baratam,R., Zhou,S., Lee,S.B., Joshi,T., Garcia,K.,
            Choi,B., Miglani,S., Subramanyam,V., Modi,H., Carpenter,C.,
            Markett,D., Corces,M.R., Mardakheh,F.K., Kulakovskiy,I.V. and
            Goodarzi,H.
  TITLE     Systematic identification of post-transcriptional regulatory
            modules
  JOURNAL   Nat Commun 15 (1), 7872 (2024)
   PUBMED   39251607
  REMARK    Erratum:[Nat Commun. 2024 Oct 28;15(1):9277. doi:
            10.1038/s41467-024-52903-4. PMID: 39468017]
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 621)
  AUTHORS   Chen,X., Fansler,M.M., Janjos,U., Ule,J. and Mayr,C.
  TITLE     The FXR1 network acts as a signaling scaffold for actomyosin
            remodeling
  JOURNAL   Cell 187 (18), 5048-5063 (2024)
   PUBMED   39106863
  REMARK    GeneRIF: The FXR1 network acts as a signaling scaffold for
            actomyosin remodeling.
REFERENCE   3  (residues 1 to 621)
  AUTHORS   Li,M., Hou,Y., Zhou,Y., Yang,Z., Zhao,H., Jian,T., Yu,Q., Zeng,F.,
            Liu,X., Zhang,Z. and Zhao,Y.G.
  TITLE     LLPS of FXR proteins drives replication organelle clustering for
            beta-coronaviral proliferation
  JOURNAL   J Cell Biol 223 (6) (2024)
   PUBMED   38587486
  REMARK    GeneRIF: LLPS of FXR proteins drives replication organelle
            clustering for beta-coronaviral proliferation.
REFERENCE   4  (residues 1 to 621)
  AUTHORS   Khan,F.A., Fang,N., Zhang,W. and Ji,S.
  TITLE     The multifaceted role of Fragile X-Related Protein 1 (FXR1) in
            cellular processes: an updated review on cancer and clinical
            applications
  JOURNAL   Cell Death Dis 15 (1), 72 (2024)
   PUBMED   38238286
  REMARK    GeneRIF: The multifaceted role of Fragile X-Related Protein 1
            (FXR1) in cellular processes: an updated review on cancer and
            clinical applications.
            Review article
            Publication Status: Online-Only
REFERENCE   5  (residues 1 to 621)
  AUTHORS   Hsu,Y.H., Pintacuda,G., Liu,R., Nacu,E., Kim,A., Tsafou,K.,
            Petrossian,N., Crotty,W., Suh,J.M., Riseman,J., Martin,J.M.,
            Biagini,J.C., Mena,D., Ching,J.K.T., Malolepsza,E., Li,T.,
            Singh,T., Ge,T., Egri,S.B., Tanenbaum,B., Stanclift,C.R.,
            Apffel,A.M., Carr,S.A., Schenone,M., Jaffe,J., Fornelos,N.,
            Huang,H., Eggan,K.C. and Lage,K.
  CONSRTM   Schizophrenia Working Group of the Psychiatric Genomics Consortium;
            Stanley Global Asia Initiatives
  TITLE     Using brain cell-type-specific protein interactomes to interpret
            neurodevelopmental genetic signals in schizophrenia
  JOURNAL   iScience 26 (5), 106701 (2023)
   PUBMED   37207277
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 621)
  AUTHORS   Tamanini,F., Willemsen,R., van Unen,L., Bontekoe,C., Galjaard,H.,
            Oostra,B.A. and Hoogeveen,A.T.
  TITLE     Differential expression of FMR1, FXR1 and FXR2 proteins in human
            brain and testis
  JOURNAL   Hum Mol Genet 6 (8), 1315-1322 (1997)
   PUBMED   9259278
REFERENCE   7  (residues 1 to 621)
  AUTHORS   Siomi,M.C., Zhang,Y., Siomi,H. and Dreyfuss,G.
  TITLE     Specific sequences in the fragile X syndrome protein FMR1 and the
            FXR proteins mediate their binding to 60S ribosomal subunits and
            the interactions among them
  JOURNAL   Mol Cell Biol 16 (7), 3825-3832 (1996)
   PUBMED   8668200
REFERENCE   8  (residues 1 to 621)
  AUTHORS   Coy,J.F., Sedlacek,Z., Bachner,D., Hameister,H., Joos,S.,
            Lichter,P., Delius,H. and Poustka,A.
  TITLE     Highly conserved 3' UTR and expression pattern of FXR1 points to a
            divergent gene regulation of FXR1 and FMR1
  JOURNAL   Hum Mol Genet 4 (12), 2209-2218 (1995)
   PUBMED   8634689
REFERENCE   9  (residues 1 to 621)
  AUTHORS   Zhang,Y., O'Connor,J.P., Siomi,M.C., Srinivasan,S., Dutra,A.,
            Nussbaum,R.L. and Dreyfuss,G.
  TITLE     The fragile X mental retardation syndrome protein interacts with
            novel homologs FXR1 and FXR2
  JOURNAL   EMBO J 14 (21), 5358-5366 (1995)
   PUBMED   7489725
REFERENCE   10 (residues 1 to 621)
  AUTHORS   Siomi,M.C., Siomi,H., Sauer,W.H., Srinivasan,S., Nussbaum,R.L. and
            Dreyfuss,G.
  TITLE     FXR1, an autosomal homolog of the fragile X mental retardation gene
  JOURNAL   EMBO J 14 (11), 2401-2408 (1995)
   PUBMED   7781595
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC352767.1, AK292633.1 and
            AC008009.5.
            
            On Mar 25, 2005 this sequence version replaced NP_005078.1.
            
            Summary: The protein encoded by this gene is an RNA binding protein
            that interacts with the functionally-similar proteins FMR1 and
            FXR2. These proteins shuttle between the nucleus and cytoplasm and
            associate with polyribosomes, predominantly with the 60S ribosomal
            subunit. Three transcript variants encoding different isoforms have
            been found for this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.24403.1,
                                           SRR1803617.183754.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000357559.9/ ENSP00000350170.3
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q26.33"
     Protein         1..621
                     /product="RNA-binding protein FXR1 isoform a"
                     /note="RNA-binding protein FXR1; FMR1 autosomal
                     protein-like protein 1"
                     /calculated_mol_wt=69590
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine. /evidence=ECO:0000269|Ref.5,
                     ECO:0007744|PubMed:22814378; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Region          3..57
                     /region_name="Tudor_Agenet_FXR1_rpt1"
                     /note="first Tudor-like Agenet domain found in fragile X
                     mental retardation syndrome-related protein 1 (FXR1) and
                     similar proteins; cd20472"
                     /db_xref="CDD:410543"
     Site            order(10,14,16,32,36,38)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:410543"
     Region          61..126
                     /region_name="Tudor_Agenet_FXR1_rpt2"
                     /note="second Tudor-like Agenet domain found in fragile X
                     mental retardation syndrome-related protein 1 (FXR1) and
                     similar proteins; cd20475"
                     /db_xref="CDD:410546"
     Site            68
                     /site_type="phosphorylation"
                     /note="Phosphotyrosine.
                     /evidence=ECO:0000250|UniProtKB:Q61584; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            order(69,78,80,96,101,103)
                     /site_type="other"
                     /note="putative peptide binding site [polypeptide
                     binding]"
                     /db_xref="CDD:410546"
     Region          123..199
                     /region_name="KH_I_FXR1_rpt1"
                     /note="first type I K homology (KH) RNA-binding domain
                     found in fragile X mental retardation syndrome-related
                     protein 1 (FXR1) and similar proteins; cd22504"
                     /db_xref="CDD:411932"
     Region          201..208
                     /region_name="CC1 domain.
                     /evidence=ECO:0000269|PubMed:39106863"
                     /note="propagated from UniProtKB/Swiss-Prot (P51114.3)"
     Region          218..280
                     /region_name="KH_I_FXR1_rpt2"
                     /note="second type I K homology (KH) RNA-binding domain
                     found in fragile X mental retardation syndrome-related
                     protein 1 (FXR1) and similar proteins; cd22507"
                     /db_xref="CDD:411935"
     Site            order(228,230..232,234..238,241..242,245..246,252..255)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:411935"
     Region          281..358
                     /region_name="KH_I_FXR1_rpt3"
                     /note="third type I K homology (KH) RNA-binding domain
                     found in fragile X mental retardation syndrome-related
                     protein 1 (FXR1) and similar proteins; cd22510"
                     /db_xref="CDD:411938"
     Site            order(291,293..295,297..301,304..305,308..309,315..318)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:411938"
     Region          353..379
                     /region_name="CC2 domain.
                     /evidence=ECO:0000269|PubMed:39106863"
                     /note="propagated from UniProtKB/Swiss-Prot (P51114.3)"
     Region          354..438
                     /region_name="FXMRP1_C_core"
                     /note="Fragile X-related 1 protein core C terminal;
                     pfam12235"
                     /db_xref="CDD:463501"
     Region          381..530
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P51114.3)"
     Site            401
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            403
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q5XI81; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            406
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:18669648,
                     ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692,
                     ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            409
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:18669648,
                     ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692,
                     ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            420
                     /site_type="phosphorylation"
                     /note="Phosphoserine, by PAK1.
                     /evidence=ECO:0000269|PubMed:20417602,
                     ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692,
                     ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            423
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:20068231,
                     ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163;
                     propagated from UniProtKB/Swiss-Prot (P51114.3)"
     Site            432
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Region          442..457
                     /region_name="RNA-binding RGG-box"
                     /note="propagated from UniProtKB/Swiss-Prot (P51114.3)"
     Site            447
                     /site_type="methylation"
                     /note="Asymmetric dimethylarginine, alternate.
                     /evidence=ECO:0000250|UniProtKB:P35922;
                     Omega-N-methylarginine, alternate.
                     /evidence=ECO:0000250|UniProtKB:P35922; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            453
                     /site_type="methylation"
                     /note="Asymmetric dimethylarginine, alternate.
                     /evidence=ECO:0000250|UniProtKB:P35922;
                     Omega-N-methylarginine, alternate.
                     /evidence=ECO:0000250|UniProtKB:P35922; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            455
                     /site_type="methylation"
                     /note="Asymmetric dimethylarginine, alternate.
                     /evidence=ECO:0000250|UniProtKB:P35922;
                     Omega-N-methylarginine, alternate.
                     /evidence=ECO:0000250|UniProtKB:P35922; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Region          462..535
                     /region_name="FXR_C1"
                     /note="Fragile X-related 1 protein C-terminal region 2;
                     pfam16096"
                     /db_xref="CDD:465019"
     Site            483
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q61584; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            485
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21406692; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            524
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:P51116; Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Site            528
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     Region          545..621
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P51114.3)"
     Region          554..620
                     /region_name="FXR_C3"
                     /note="Fragile X-related 1 protein C-terminal region 3;
                     pfam16097"
                     /db_xref="CDD:435134"
     Site            587
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332,
                     ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163;
                     propagated from UniProtKB/Swiss-Prot (P51114.3)"
     Site            611
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0007744|PubMed:21406692,
                     ECO:0007744|PubMed:23186163; propagated from
                     UniProtKB/Swiss-Prot (P51114.3)"
     CDS             1..621
                     /gene="FXR1"
                     /gene_synonym="CMYO9A; CMYO9B; CMYP9A; CMYP9B; FXR1P;
                     MYOPMIL; MYORIBF"
                     /coded_by="NM_005087.4:17..1882"
                     /note="isoform a is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS3238.1"
                     /db_xref="GeneID:8087"
                     /db_xref="HGNC:HGNC:4023"
                     /db_xref="MIM:600819"
ORIGIN      
        1 maeltvevrg sngafykgfi kdvhedsltv vfennwqper qvpfnevrlp pppdikkeis
       61 egdevevysr andqepcgww lakvrmmkge fyvieyaacd atyneivtfe rlrpvnqnkt
      121 vkkntffkct vdvpedlrea canenahkdf kkavgacrif yhpettqlmi lsaseatvkr
      181 vnilsdmhlr sirtklmlms rneeatkhle ctkqlaaafh eefvvredlm glaigthgsn
      241 iqqarkvpgv taieldedtg tfriygesad avkkargfle fvedfiqvpr nlvgkvigkn
      301 gkviqeivdk sgvvrvrieg dnenklpred gmvpfvfvgt kesignvqvl leyhiaylke
      361 veqlrmerlq ideqlrqigs rsysgrgrgr rgpnytsgyg tnselsnpse teserkdels
      421 dwslageddr dsrhqrdsrr rpggrgrsvs ggrgrggprg gkssissvlk dpdsnpysll
      481 dntesdqtad tdaseshhst nrrrrsrrrr tdedavlmdg mtesdtasvn englvtvady
      541 israesqsrq rnlpretlak nkkemakdvi eehgpsekai ngptsasgdd isklqrtpge
      601 ekintlkeen tqeaavlngv s
//
LOCUS       NP_001284516             524 aa            linear   VRT 19-JUN-2025
DEFINITION  cytochrome P450 17A2 [Cynoglossus semilaevis].
ACCESSION   NP_001284516
VERSION     NP_001284516.1
DBSOURCE    REFSEQ: accession NM_001297587.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EU732518.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU732518.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03753709, SAMN03753710
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..524
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="1"
                     /map="1"
     Protein         1..524
                     /product="cytochrome P450 17A2"
                     /note="cytochrome P450c17-II"
                     /calculated_mol_wt=57816
     Region          87..511
                     /region_name="cytochrome_P450"
                     /note="cytochrome P450 (CYP) superfamily; cl41757"
                     /db_xref="CDD:477761"
     Site            order(148,152,159,206,320..321,324..325,328..329,332,383,
                     393,395,418,454..456,460..464,467..468)
                     /site_type="other"
                     /note="heme binding site [chemical binding]"
                     /db_xref="CDD:410766"
     Site            order(232..233,320,323..324,328,391..394)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:410766"
     CDS             1..524
                     /gene="cyp17a2"
                     /coded_by="NM_001297587.1:27..1601"
                     /db_xref="GeneID:103389439"
ORIGIN      
        1 mfthllscll lssssspffl illslvllvi lylfgrgsfs sssssplpnt aggsipclpr
       61 lpllgslpwl sqhlpphllf cklshrygsl fgfylgpyyt lvvnnhhhar evllqrgrdf
      121 agrprmvttd lltrggkdia fsdysalwkl hrrlvhnsft lfgegssrlq dialssvdgl
      181 caellsstgs afdpapaitr aitnavcklv fsatyepgda elqevihynd givqtiargg
      241 lvdiypwmkv fpnksltklk dciyirdrll trkleehkas lsdgdprdll dallkgqtar
      301 stgsqdeqis ddhvlmtaae afgagvetts ttllwilayl lhhpevqrrv qqeldeqvgs
      361 eravnmsdrg rlpyldcvin egmrirpvsp vliphmamtn ssigghsipr gtrvlvnmwa
      421 ihhdphhwdk pdlftperfl dangqrdtps cflpfgagpr vcvgeslarl elflflssll
      481 qrisfklpdg asppnlqgrl gvvlqplpyk vtvsprlgwe ggak
//
LOCUS       NP_001284508             352 aa            linear   VRT 19-JUN-2025
DEFINITION  membrane progestin receptor alpha-B [Cynoglossus semilaevis].
ACCESSION   NP_001284508 XP_008321809
VERSION     NP_001284508.1
DBSOURCE    REFSEQ: accession NM_001297579.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from JQ322819.1.
            
            On Jul 3, 2014 this sequence version replaced XP_008321809.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: JQ322819.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN03753709
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..352
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="13"
                     /map="13"
     Protein         1..352
                     /product="membrane progestin receptor alpha-B"
                     /note="membrane progestin receptor alpha"
                     /calculated_mol_wt=40677
     Region          70..296
                     /region_name="HlyIII"
                     /note="Haemolysin-III related; pfam03006"
                     /db_xref="CDD:427098"
     CDS             1..352
                     /gene="paqr7b"
                     /coded_by="NM_001297579.1:154..1212"
                     /db_xref="GeneID:103388542"
ORIGIN      
        1 matvvmeqig rlfinaqqlr qipqllesaf ptlpctvkvs dvpwvfqerh ilsgyrqpdq
       61 swryyfltlf qrhnetlnvw thllaaliil vkwqeisetv dflrdphaqp lfivllaaft
      121 ylsfsalahl lsakselscy tfyfldyigv avyqygsala hyyyaiekew htrvqglflp
      181 aaaflawltc fgccygkyas rdipkfvlkl fqvvpsalay cldispvvhr iyscyqegcs
      241 dpvvayhfyh vvfflisayf fccphperff pgkcdfigqg hqifhvfvvv ctltqiealr
      301 tdfterrply erlhgdlahd avalfiftac csaltafyvr krvrvalhek ee
//
LOCUS       NP_001124554            1174 aa            linear   PRI 19-JUN-2025
DEFINITION  SMC5-SMC6 complex localization factor protein 2 [Pongo abelii].
ACCESSION   NP_001124554
VERSION     NP_001124554.1
DBSOURCE    REFSEQ: accession NM_001131082.1
KEYWORDS    RefSeq.
SOURCE      Pongo abelii (Sumatran orangutan)
  ORGANISM  Pongo abelii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Pongo.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CR857575.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR857575.1, SRR6713218.2874.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2058382, SAMEA2058383
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Pongo abelii"
                     /db_xref="taxon:9601"
                     /chromosome="8"
                     /map="8"
     Protein         1..1174
                     /product="SMC5-SMC6 complex localization factor protein 2"
                     /note="Protein FAM178A; SMC5-SMC6 complex localization
                     factor 2"
                     /calculated_mol_wt=131886
     Region          1..110
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     Region          162..233
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     Region          256..374
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     Region          396..474
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     Site            482
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8IX21; propagated from
                     UniProtKB/Swiss-Prot (Q5REF4.1)"
     Region          498..621
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     Site            604
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8IX21; propagated from
                     UniProtKB/Swiss-Prot (Q5REF4.1)"
     Site            608
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8IX21; propagated from
                     UniProtKB/Swiss-Prot (Q5REF4.1)"
     Site            615
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8IX21; propagated from
                     UniProtKB/Swiss-Prot (Q5REF4.1)"
     Region          635..666
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     Region          636..1174
                     /region_name="Interaction with SIMC1.
                     /evidence=ECO:0000250|UniProtKB:Q8IX21"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     Region          658..1032
                     /region_name="CANIN"
                     /note="Coiled-coil and Nse Interacting (CANIN) domain;
                     pfam14816"
                     /db_xref="CDD:464331"
     Region          665..1167
                     /region_name="NSE6-like domain.
                     /evidence=ECO:0000250|UniProtKB:Q8IX21"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     Region          703..1174
                     /region_name="Required for interaction with SLF1 and
                     RAD18. /evidence=ECO:0000250|UniProtKB:Q8IX21"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5REF4.1)"
     CDS             1..1174
                     /gene="SLF2"
                     /gene_synonym="C10orf6; FAM178A"
                     /coded_by="NM_001131082.1:149..3673"
                     /db_xref="GeneID:100127098"
ORIGIN      
        1 mtrrcmparp gfpsspapgs spprchlrpg stahaaagkr tespgdrkqs iidffkpask
       61 qgrhmldspq ksnikyggsr lsitgterfe rklsspkksk tkrvppeksp iieafmkgvk
      121 ehhedhgihe scrpcvslas kylakgtniy vpssyhlake mkslkknhrs perrkslfih
      181 ennekndrdr gktnadskkq ttvaeadifk nssrslssrs slsrhhpges plgakfqlsl
      241 asycrerelk rlrkeqmeqr insensfsea snlslksssi erkykprqeq rkqndvipgk
      301 nnlsnvengh lsrkrsssds weptsagskq nkfpekrkrn svdsdlkstr esmipkares
      361 flekrpdgph qkekfikhia lktpgdvlrl ediskepnde tdcssaglap snsgssghhs
      421 trnsdqirva gtketkmqkp hlplsqeksa ikkasnlqkn kttssmtkek etklpllshv
      481 psagsslvpl nakncalpvs kkdkersssk ecsghstest khkehkaktn kadsnvssgk
      541 isggplcsey gaptksppaa levvpcvpsp aapsdkapse ressgnsnag ssalkrklrg
      601 dfdsdeeslg ynldsdeeee tlksleeima lnfnqtpatt gkppalskel rsqssdytgh
      661 dhpgtytntl erlvkemedt qrldelqkql qedirqgrgi kspirigeed stddedglle
      721 ehkeflkkfs vtidaipdhh pgeeifnfln sgkifnqytl dlrdsgfigq saveklilks
      781 gktdqifltt qgfltsayhy vqcpvpvlkw lfrmmsvhtd civsvqilst lmeitirndt
      841 fsdspvwpwi pslsdvaavf fnmgidfrsl fplenlqpdf nedylvsetq ttsrgkesed
      901 ssykpifstl petnilnvvk flglctsihp egyqdreiml lilmlfkmsl ekqlkqiplv
      961 dfqsllinlm knirdwntkv pelclginel sshphnllwl vqlvpnwtsr grqlrqclsl
     1021 viisklldek hedvpnasnl qvsvlhrylv qmkpsdllkk mvlkkkaeqp dgiiddslhl
     1081 elekqayylt yillhlvgev scshsfssgq rkhfvllcga lekhvkcdir edarlfyrtk
     1141 vkdlvarihg kwqeiiqncr ptqgqlhdfw vpds
//
LOCUS       NP_001315173             697 aa            linear   VRT 19-JUN-2025
DEFINITION  long-chain-fatty-acid--CoA ligase 1a [Cynoglossus semilaevis].
ACCESSION   NP_001315173
VERSION     NP_001315173.1
DBSOURCE    REFSEQ: accession NM_001328244.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KP033458.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KP033458.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06859058 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="9"
                     /map="9"
     Protein         1..697
                     /product="long-chain-fatty-acid--CoA ligase 1a"
                     /EC_number="6.2.1.3"
                     /note="long chain fatty acyl CoA synthetase; acyl-CoA
                     synthetase long chain family member 1"
                     /calculated_mol_wt=77851
     Region          116..693
                     /region_name="LC-FACS_euk"
                     /note="Eukaryotic long-chain fatty acid CoA synthetase
                     (LC-FACS); cd05927"
                     /db_xref="CDD:341250"
     Site            order(272,275..280,282..283)
                     /site_type="other"
                     /note="acyl-activating enzyme (AAE) consensus motif"
                     /db_xref="CDD:341250"
     Site            order(275,392..393,455..460,539,551,554,566,672)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341250"
     Site            order(275,319..320,365,367..368,371,392..393,455..460,539,
                     551,554,563..566,649)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341250"
     Site            order(319,367..368,371,392,563..565,647,649)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341250"
     CDS             1..697
                     /gene="acsl1a"
                     /gene_synonym="ACSL; acsl1"
                     /coded_by="NM_001328244.1:100..2193"
                     /db_xref="GeneID:103383665"
ORIGIN      
        1 mqtqevlrql ripdldevrq yvrglptnal mgmgafaait tywfasrpra lkppcdlamq
       61 sveipgeera rrsalnegde hptyfysdar tmyqmfqrgl rvsndgpclg srkpgqpydw
      121 lsykevsdra enlgsaflhk ghsqtgdkfi gvfsqnrpew tiselacyty slvvvplydt
      181 lgqeaigfii ekavistvic dvpdkaqiil dcvngkgqsv ktivimedfh sdlvtrgkdc
      241 gveilslkdf edlgkahhqk pmppkpedla licftsgttg npkgamlthc nvisntaafl
      301 ritkvhcmld qhdihisylp lahvferlvq gvvlihgari gyfqggirll mddlktlqpt
      361 vfpvvprlln rmfdkvfsqa ntplkrwvld fafrrkesem krgvvrkdsm wdrlifkkvq
      421 aslggrvrlm itgaapvspt iltflraalg cqfyegygqt ectagctmsm pgdwtaghvg
      481 pplpcntvkl vdvaemnyls vngegevcvk gpnvfqgylk dpektaeald kdgwlhtgdi
      541 grwlpngtlk iidrkkhifk laqgeyvape kietiysrse avaqifihgd slqaclvgiv
      601 vtdpdflpiw akskgiegsy selckkkevk dailqellql gkdaglktfe qvrdialhse
      661 mftvqngllt ptlkakrael qkrfrelide lyakikm
//
LOCUS       NP_001295108             375 aa            linear   VRT 19-JUN-2025
DEFINITION  actin, cytoplasmic 2 [Cynoglossus semilaevis].
ACCESSION   NP_001295108
VERSION     NP_001295108.1
DBSOURCE    REFSEQ: accession NM_001308179.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KF932267.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KF932267.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN08493838 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="17"
                     /map="17"
     Protein         1..375
                     /product="actin, cytoplasmic 2"
                     /note="putative beta-actin"
                     /calculated_mol_wt=41636
     Region          6..370
                     /region_name="ASKHA_NBD_actin"
                     /note="nucleotide-binding domain (NBD) of actin and
                     similar proteins; cd10224"
                     /db_xref="CDD:466823"
     CDS             1..375
                     /gene="actb2"
                     /gene_synonym="actb; beta-actin"
                     /coded_by="NM_001308179.1:1..1128"
                     /db_xref="GeneID:103393304"
ORIGIN      
        1 medeiaalvv dngsgmckag fagddaprav fpsivgrprh qgvmvgmgqk dsyvgdeaqs
       61 krgiltlkyp iehgivtnwd dmekiwhhtf ynelrvapee hpvllteapl npkanrekmt
      121 qimfetfntp amyvaiqavl slyasgrttg ivmdsgdgvt htvpiyegya lphailrldl
      181 agrdltdylm kiltergysf tttaereivr dikeklcyva ldfeqemgta assssleksy
      241 elpdgqviti gnerfrcpea lfqpsflgme scgihettyn simkcdvdir kdlyantvls
      301 ggttmypgia drmqkeital apstmkikii apperkysvw iggsilasls tfqqmwiskq
      361 eydesgpsiv hrkcf
//
LOCUS       NP_001281133             158 aa            linear   VRT 19-JUN-2025
DEFINITION  lutropin subunit beta precursor [Cynoglossus semilaevis].
ACCESSION   NP_001281133 XP_008319616
VERSION     NP_001281133.1
DBSOURCE    REFSEQ: accession NM_001294204.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from JQ277934.1.
            
            On Jun 26, 2014 this sequence version replaced XP_008319616.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: JQ277934.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03753709, SAMN03753710
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..158
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="12"
                     /map="12"
     Protein         1..158
                     /product="lutropin subunit beta precursor"
                     /note="luteinizing hormone beta subunit"
                     /calculated_mol_wt=14920
     sig_peptide     1..25
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2754
     Region          37..151
                     /region_name="GHB"
                     /note="Glycoprotein hormone beta chain homologues;
                     smart00068"
                     /db_xref="CDD:214502"
     Site            order(40,65,69,97,128,130)
                     /site_type="other"
                     /note="cysteine knot motif"
                     /db_xref="CDD:200450"
     Site            order(47,50,64..77,96..97,133,135,138..143)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:200450"
     Site            order(77,135..136,139,141..143)
                     /site_type="other"
                     /note="receptor binding site [polypeptide binding]"
                     /db_xref="CDD:200450"
     CDS             1..158
                     /gene="lhb"
                     /coded_by="NM_001294204.1:47..523"
                     /db_xref="GeneID:103386947"
ORIGIN      
        1 mlvavqmhrl ivhltltlll passpdwllt paaafmlpgc qlinqtvsle kegcpichsv
       61 etticsghcr tkepnikvpl ykmpsfqspf nvfqqvctye hvhyktfelp dcppgvdpti
      121 typvalschc glcdmkkadc tveslrpdic mndvlfny
//
LOCUS       NP_001281162             223 aa            linear   VRT 19-JUN-2025
DEFINITION  CD28 molecule precursor [Cynoglossus semilaevis].
ACCESSION   NP_001281162 XP_008323710
VERSION     NP_001281162.1
DBSOURCE    REFSEQ: accession NM_001294233.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 223)
  AUTHORS   Hu,Y.H., Sun,B.G., Deng,T. and Sun,L.
  TITLE     Molecular characterization of Cynoglossus semilaevis CD28
  JOURNAL   Fish Shellfish Immunol 32 (5), 934-938 (2012)
   PUBMED   22530241
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from JN380202.1.
            
            On Jun 26, 2014 this sequence version replaced XP_008323710.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: JN380202.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN03753709
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..223
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="14"
                     /map="14"
     Protein         1..223
                     /product="CD28 molecule precursor"
                     /calculated_mol_wt=22980
     sig_peptide     1..18
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2084
     CDS             1..223
                     /gene="si:dkey-1h24.6"
                     /coded_by="NM_001294233.1:19..690"
                     /db_xref="GeneID:103389879"
ORIGIN      
        1 mrvcwmlviv lgcswseask slgkdcgnvq lrsfcsicnt pvlvpcpnit aaemvfklfk
       61 dqeylsnisc ihsnstltce lsktsadiqv qkhqqeksvs flltgvtdss qgiygcegtk
      121 kfpppmitvq sdvriqvlqg hickckensr psgedpqfrl dllliilvvl lsiysiifti
      181 iavvqwvkqr stdshndyin tkprapqdrk rnkgvqkpvp rhf
//
LOCUS       NP_001244436             299 aa            linear   PRI 19-JUN-2025
DEFINITION  non-structural maintenance of chromosomes element 3 homolog [Macaca
            mulatta].
ACCESSION   NP_001244436 XP_001109764
VERSION     NP_001244436.1
DBSOURCE    REFSEQ: accession NM_001257507.1
KEYWORDS    RefSeq.
SOURCE      Macaca mulatta (Rhesus monkey)
  ORGANISM  Macaca mulatta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
REFERENCE   1  (residues 1 to 299)
  AUTHORS   Zimin,A.V., Cornish,A.S., Maudhoo,M.D., Gibbs,R.M., Zhang,X.,
            Pandey,S., Meehan,D.T., Wipfler,K., Bosinger,S.E., Johnson,Z.P.,
            Tharp,G.K., Marcais,G., Roberts,M., Ferguson,B., Fox,H.S.,
            Treangen,T., Salzberg,S.L., Yorke,J.A. and Norgren,R.B. Jr.
  TITLE     A new rhesus macaque assembly and annotation for next-generation
            sequencing analyses
  JOURNAL   Biol Direct 9 (1), 20 (2014)
   PUBMED   25319552
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 299)
  AUTHORS   Yan,G., Zhang,G., Fang,X., Zhang,Y., Li,C., Ling,F., Cooper,D.N.,
            Li,Q., Li,Y., van Gool,A.J., Du,H., Chen,J., Chen,R., Zhang,P.,
            Huang,Z., Thompson,J.R., Meng,Y., Bai,Y., Wang,J., Zhuo,M.,
            Wang,T., Huang,Y., Wei,L., Li,J., Wang,Z., Hu,H., Yang,P., Le,L.,
            Stenson,P.D., Li,B., Liu,X., Ball,E.V., An,N., Huang,Q., Zhang,Y.,
            Fan,W., Zhang,X., Li,Y., Wang,W., Katze,M.G., Su,B., Nielsen,R.,
            Yang,H., Wang,J., Wang,X. and Wang,J.
  TITLE     Genome sequencing and comparison of two nonhuman primate animal
            models, the cynomolgus and Chinese rhesus macaques
  JOURNAL   Nat Biotechnol 29 (11), 1019-1023 (2011)
   PUBMED   22002653
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from JU335479.1.
            
            On Apr 12, 2012 this sequence version replaced XP_001109764.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: JU335479.1, JV622409.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Macaca mulatta"
                     /db_xref="taxon:9544"
                     /chromosome="7"
                     /map="7"
     Protein         1..299
                     /product="non-structural maintenance of chromosomes
                     element 3 homolog"
                     /note="melanoma-associated antigen G1; necdin-like 2; NSE3
                     homolog, SMC5-SMC6 complex component"
                     /calculated_mol_wt=33690
     Region          87..256
                     /region_name="MAGE"
                     /note="MAGE homology domain; pfam01454"
                     /db_xref="CDD:426270"
     CDS             1..299
                     /gene="NSMCE3"
                     /gene_synonym="NDNL2"
                     /coded_by="NM_001257507.1:95..994"
                     /db_xref="GeneID:712714"
ORIGIN      
        1 mlqkprnrgr sggqaerdsd wsrggnsgas ragehararr dgfaeeapst srgpggsqgs
       61 qgarrsqasp avgprtqkqq elkvselvqf llikdqkkip ikradilkhv igdykdifpd
      121 llkraaerlq yvfgyklvel epksntyili ntlepveeda evrgdqgtpt tgllmivlgl
      181 ifmkgntvke tevwdflrrl gvyptkkhfi fgdpkklite dfvrqryley rriphtdpvd
      241 yefqwgprtn letskmkvlk fvakvhnqdp kdwpaqycea ladeenrarp qpsgsapss
//
LOCUS       NP_001281116             735 aa            linear   VRT 19-JUN-2025
DEFINITION  hypoxia inducible factor 1 subunit alpha a [Cynoglossus
            semilaevis].
ACCESSION   NP_001281116 XP_008305696
VERSION     NP_001281116.1
DBSOURCE    REFSEQ: accession NM_001294187.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from HQ909440.1.
            
            On Jun 26, 2014 this sequence version replaced XP_008305696.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HQ909440.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN03753709
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="1"
                     /map="1"
     Protein         1..735
                     /product="hypoxia inducible factor 1 subunit alpha a"
                     /note="hypoxia inducible factor 1, alpha subunit (basic
                     helix-loop-helix transcription factor); hypoxia-inducible
                     factor 1 alpha; hypoxia inducible factor 1 alpha subunit"
                     /calculated_mol_wt=82110
     Region          12..82
                     /region_name="bHLH_SF"
                     /note="basic Helix Loop Helix (bHLH) domain superfamily;
                     cl00081"
                     /db_xref="CDD:469605"
     Site            order(25..26,28,33,54..55)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:381392"
     Site            order(31..32,35..36,38..39,43,55..56,59..60,63,65..66,
                     69..70)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:381392"
     Region          88..151
                     /region_name="PAS"
                     /note="PAS domain; smart00091"
                     /db_xref="CDD:214512"
     Region          251..338
                     /region_name="PAS_3"
                     /note="PAS fold; pfam08447"
                     /db_xref="CDD:430001"
     Site            order(254,258,264,277..280,306,311)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:238075"
     Site            order(274,278,286,289..290,318,320)
                     /site_type="other"
                     /note="heme pocket [chemical binding]"
                     /db_xref="CDD:238075"
     Region          537..564
                     /region_name="HIF-1"
                     /note="Hypoxia-inducible factor-1; pfam11413"
                     /db_xref="CDD:463274"
     Region          698..734
                     /region_name="HIF-1a_CTAD"
                     /note="HIF-1 alpha C terminal transactivation domain;
                     pfam08778"
                     /db_xref="CDD:430212"
     CDS             1..735
                     /gene="hif1aa"
                     /gene_synonym="hif-1alpha; HIF-alpha; hif1a"
                     /coded_by="NM_001294187.1:244..2451"
                     /db_xref="GeneID:103376909"
ORIGIN      
        1 mdtgivpekk rvsserrkek srdaarcrrg kesevfyela qqlplphsis ssldkasimr
       61 ltisylrirk llnpddmmak eeteldiqln ssylkaldgf lmvlseggdi iyltenvnkc
      121 lglaqfdltg hsvfdfthpc dqeelremli hrsgskknke qnterslflr mkctltsrgr
      181 tvnvksatwk vlhcsghvrv ydnnteqtng hkdppvpyli licdpiphps nieapldtkt
      241 flsrhtmdmk ftycderite lmgydpedll nrsvyeyyha ldsdhlnkth hslfakgqvs
      301 tgqyrmlakr ggfvwvetqa tviynnknsq pqcvvcvnfv lsgiqeekli lsleqtedvk
      361 pvkeeqeeek aevlsglsdm pltllkeeed tkvpeldvtk vftqsvdtss slydqlkgep
      421 ealtllapaa gdtiisldfs cspdseiqll ndaplyndvm lppseplnit vttgsdnsks
      481 esyappppaa ttsncssetd sqldfcfpmd sdfkldyvek lfaidtepkt sfnseimadi
      541 dlemlapyip mdddfqlrcl tpeepltgvq vksqhssplh ikqdltgsyp sspasrtasp
      601 alpepvnsln larligkrsp qsdkdvslrt lvaqntqrkr klcdlkeiie qgtllegqge
      661 qgkklkatel gstttilllp sdlasrllgs tsdgtgslft lphltrydce vnaplqgrqy
      721 llqgeellra ldhvi
//
LOCUS       NP_001121149             365 aa            linear   VRT 19-JUN-2025
DEFINITION  zinc finger TRAF-type-containing protein 1-B [Xenopus laevis].
ACCESSION   NP_001121149
VERSION     NP_001121149.1
DBSOURCE    REFSEQ: accession NM_001127677.1
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (residues 1 to 365)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC122465.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC122465.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00012418, SAMD00012419
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Xenopus laevis"
                     /db_xref="taxon:8355"
                     /chromosome="6S"
                     /map="6S"
     Protein         1..365
                     /product="zinc finger TRAF-type-containing protein 1-B"
                     /note="cysteine and histidine-rich protein 1-B; Cysteine
                     and histidine-rich protein 1B; cysteine/histidine-rich 1 S
                     homeolog"
                     /calculated_mol_wt=41358
     Region          1..56
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q2TAD9.2)"
     Region          61..122
                     /region_name="RING-HC_CYHR1"
                     /note="RING finger, HC subclass, found in cysteine and
                     histidine-rich protein 1 (CYHR1) and similar proteins;
                     cd16505"
                     /db_xref="CDD:438168"
     Region          127..>188
                     /region_name="Sina"
                     /note="Seven in absentia protein family; pfam03145"
                     /db_xref="CDD:460824"
     Region          210..365
                     /region_name="CYHR1_C"
                     /note="C-terminal domain of cysteine and histidine-rich
                     protein 1 and similar proteins; cd22861"
                     /db_xref="CDD:439370"
     CDS             1..365
                     /gene="zftraf1.S"
                     /gene_synonym="chrp; cyhr1; cyhr1-a; cyhr1-b; cyhr1.S;
                     tmem276.S; zftraf1; zftraf1-b"
                     /coded_by="NM_001127677.1:59..1156"
                     /db_xref="GeneID:733442"
                     /db_xref="Xenbase:XB-GENE-5917347"
ORIGIN      
        1 mseereapgp lasssaglga evgqeevpgg agparllllp sdsdgppkkr lrseaepgsv
       61 rleerlysvl ccavcldlpk asvyqctngh lmcagcfihl ladarlkeeq atcpncrcei
      121 skslccrnla vekaiselps dcgfclkqfp rsllerhkke ecqdrvtqck ykrigcpwqg
      181 pyheltvhes ecchptktgn elmeildemd qthkkemqly nsifsllsfe kigytevqfr
      241 pyrtddfitr lyyetprftv lnqtwvlkar vndsernpnl sckrtlsfql ilkskvnspm
      301 ecsflllkgp yddvkihpvi yqfvftnenn eteyvplpii dsvecnklla akninlrlfi
      361 fqiqk
//
LOCUS       NP_001127452             463 aa            linear   PRI 19-JUN-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 [Pongo abelii].
ACCESSION   NP_001127452
VERSION     NP_001127452.1
DBSOURCE    REFSEQ: accession NM_001133980.1
KEYWORDS    RefSeq.
SOURCE      Pongo abelii (Sumatran orangutan)
  ORGANISM  Pongo abelii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Pongo.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CR859531.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR859531.1, SRR6713218.15311.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2058381, SAMEA2058382
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Pongo abelii"
                     /db_xref="taxon:9601"
                     /chromosome="5"
                     /map="5"
     Protein         1..463
                     /product="tRNA (guanine(10)-N(2))-methyltransferase
                     TRMT11"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     methyltransferase 11 homolog"
                     /calculated_mol_wt=53248
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:Q7Z4G4; propagated from
                     UniProtKB/Swiss-Prot (Q5R962.1)"
     Region          10..332
                     /region_name="TIGR01177"
                     /note="putative methyltransferase, TIGR01177 family"
                     /db_xref="CDD:273486"
     Region          197..386
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..463
                     /gene="TRMT11"
                     /coded_by="NM_001133980.1:23..1414"
                     /db_xref="GeneID:100174524"
ORIGIN      
        1 malsctlnry lllmaqehle frlpeiksll slfggqfgss qetfgkspfw ilsipsedia
       61 rnlmkrtvca ksifelwghg qspeelyssl knypvekmvp flhsdstyki kihtfnktlt
      121 qeekikrida leflpfegkv nlkkpqhvfs vledygldpn cipenphniy fgrwiadgqr
      181 eliesysvkk rhfigntsmd aglsfimanh gkvkendivf dpfvgtggll iacahfgayv
      241 ygtdidyntv hglgkatrkn qkwrgpdeni ranlrqygle kyyldvlvsd askpswrkgt
      301 yfdaiitdpp ygirestrrt gsqkeipkgi ekwekcpesh vpvslsyhls dmfldllnfa
      361 aetlvlggrl vywlpvytpe yteemvpwhp clelisnceq klsshtsrrl itmekvkkfe
      421 nrdqyshlls dhflpyqghn sfrekyfsgv tkriakeeks tqe
//
LOCUS       NP_001281121             261 aa            linear   VRT 19-JUN-2025
DEFINITION  aquaporin-1a.1 [Cynoglossus semilaevis].
ACCESSION   NP_001281121
VERSION     NP_001281121.1
DBSOURCE    REFSEQ: accession NM_001294192.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 261)
  AUTHORS   Guo,H., Wei,M., Liu,Y., Zhu,Y., Xu,W., Meng,L., Wang,N., Shao,C.,
            Lu,S., Gao,F., Cui,Z., Wei,Z., Zhao,F. and Chen,S.
  TITLE     Molecular cloning and expression analysis of the aqp1aa gene in
            half-smooth tongue sole (Cynoglossus semilaevis)
  JOURNAL   PLoS One 12 (4), e0175033 (2017)
   PUBMED   28380032
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from HM013715.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HM013715.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN01766803
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="20"
                     /map="20"
     Protein         1..261
                     /product="aquaporin-1a.1"
                     /EC_number="2.7.1.21"
                     /note="aquaporin 1 (Colton blood group)"
                     /calculated_mol_wt=27318
     Region          3..219
                     /region_name="MIP"
                     /note="Major intrinsic protein; pfam00230"
                     /db_xref="CDD:395174"
     Site            order(50,68..70,180..181,184,187)
                     /site_type="active"
                     /note="amphipathic channel [active]"
                     /db_xref="CDD:238204"
     Site            order(70..72,184..186)
                     /site_type="other"
                     /note="Asn-Pro-Ala signature motifs"
                     /db_xref="CDD:238204"
     CDS             1..261
                     /gene="aqp1a.1"
                     /gene_synonym="aqp1"
                     /coded_by="NM_001294192.1:64..849"
                     /db_xref="GeneID:103396389"
ORIGIN      
        1 mkefkskefw ravlaelvgm tlfiflslas aigntnnsnp dqevkvllaf glaiatlaqs
       61 lghisgahld pavtlgmlas cqisvfkaam ymiaqmlgsa lasgimygar psttdalgln
      121 alngvtpsqg vgiellatfq lvlcviavtd krrrdvtgsa plaiglsvtl ghlaaisytg
      181 cginparsfg palilnnfen hwvywvgpmc ggvaaaliyd fmlspkfedf pdrmkvlvsg
      241 pagdydvngg ndvgnvemgt k
//
LOCUS       NP_001284515             212 aa            linear   VRT 19-JUN-2025
DEFINITION  high mobility group protein B2a [Cynoglossus semilaevis].
ACCESSION   NP_001284515
VERSION     NP_001284515.1
DBSOURCE    REFSEQ: accession NM_001297586.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 212)
  AUTHORS   Long,H., Chen,C., Zhang,J. and Sun,L.
  TITLE     Antibacterial and antiviral properties of tongue sole (Cynoglossus
            semilaevis) high mobility group B2 protein are largely independent
            on the acidic C-terminal domain
  JOURNAL   Fish Shellfish Immunol 37 (1), 66-74 (2014)
   PUBMED   24468324
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KF573414.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KF573414.1, GH234892.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN08193245, SAMN08493829
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..212
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="9"
                     /map="9"
     Protein         1..212
                     /product="high mobility group protein B2a"
                     /note="putative high mobility group B2 protein; high
                     mobility group box 2"
                     /calculated_mol_wt=23819
     Region          7..75
                     /region_name="HMG-box_HMGB_rpt1"
                     /note="first high mobility group (HMG)-box found in the
                     high mobility group protein B (HMGB) family; cd21978"
                     /db_xref="CDD:438794"
     Site            order(7..9,12,15..16,18..20,24,27,34..35,37..38,40..42,
                     44..45,49)
                     /site_type="other"
                     /note="p53 binding site [polypeptide binding]"
                     /db_xref="CDD:438794"
     Site            order(7,9..10,12..16,19..20,35,37..38,40..42,45,48)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:438794"
     Region          93..163
                     /region_name="HMG-box_HMGB_rpt2"
                     /note="second high mobility group (HMG)-box found in the
                     high mobility group protein B (HMGB) family; cd21979"
                     /db_xref="CDD:438795"
     Site            order(94..100,102..104,106..107,110,122..123,125..127,130,
                     133,152,155..156,159,162..163)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:438795"
     CDS             1..212
                     /gene="hmgb2a"
                     /gene_synonym="hmgb2"
                     /coded_by="NM_001297586.1:1..639"
                     /db_xref="GeneID:103384319"
ORIGIN      
        1 mtkdpnrprg ktssyaffva tcreehkkkh pgtsvnfsef skkcserwkt ksgkekgkfe
       61 elakndkvry eremktyvpp kgakkgkkek dpnapkrpps affvfcsdhr prikeehpgi
      121 sigeiakklg elwstqsskd kapyeakaak lkekyekeva ayraksgtgk sdagkksgpg
      181 rppkkaepad ddddddddee eddddddddd de
//
LOCUS       NP_001079316             315 aa            linear   VRT 19-JUN-2025
DEFINITION  olfactory receptor family 11 subfamily L member 1 L homeolog
            [Xenopus laevis].
ACCESSION   NP_001079316
VERSION     NP_001079316.1
DBSOURCE    REFSEQ: accession NM_001085847.1
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ250756.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ250756.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Xenopus laevis"
                     /db_xref="taxon:8355"
                     /chromosome="3L"
                     /map="3L"
     Protein         1..315
                     /product="olfactory receptor family 11 subfamily L member
                     1 L homeolog"
                     /function="putative receptor for odorants"
                     /note="olfactory receptor class II (xb180 gene); olfactory
                     receptor, family 11, subfamily L, member 1; olfactory
                     receptor family 11 subfamily L member 1 like L homeolog"
                     /calculated_mol_wt=35849
     Region          23..291
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          25..49
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410628"
     Region          58..80
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410628"
     Region          96..118
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410628"
     Region          141..157
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410628"
     Region          194..217
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:410628"
     Region          236..258
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:410628"
     Region          267..291
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:410628"
     CDS             1..315
                     /gene="or11l1.L"
                     /gene_synonym="or11l1; or11l1l.L; or2-b; xb180"
                     /coded_by="NM_001085847.1:1..948"
                     /db_xref="GeneID:378628"
                     /db_xref="Xenbase:XB-GENE-6252392"
ORIGIN      
        1 mknqtlvsei vllgfqnlhn ikiplfslfl liyimiicen vliivlvsss rnlqspmyff
       61 lqqlsvcdfl estiivpill qtvknegatm yfvdclvqfy ffslteafec fllavmsydr
      121 yvaiciplry ssimshrvcv tlifvswlls ligvliiaki matlqfcdqn tinhffcdff
      181 pivelscsdt ylvhinimlq sipvifipfi litisyicia hailkivsnt grqkafstcs
      241 shlavvsify galiaiyvvp prkelqtisk vlsllytvvt plvnpliysl rskdirdvlq
      301 rilnrlhqap rgqiy
//
LOCUS       NP_001281155             107 aa            linear   VRT 19-JUN-2025
DEFINITION  thioredoxin b [Cynoglossus semilaevis].
ACCESSION   NP_001281155 XP_008321486
VERSION     NP_001281155.1
DBSOURCE    REFSEQ: accession NM_001294226.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 107)
  AUTHORS   Li,Y.X., Hu,Y.H., Sun,J.S. and Sun,L.
  TITLE     CsCXCe1: A novel Cynoglossus semilaevis CXC chemokine that
            functions as a chemoattractant and an immunomodulator for
            peripheral blood leukocytes
  JOURNAL   Dev Comp Immunol 37 (1), 55-64 (2012)
   PUBMED   22210524
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from JN862929.1.
            
            On Jun 26, 2014 this sequence version replaced XP_008321486.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: JN862929.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01766803, SAMN04556680
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..107
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="1"
                     /map="1"
     Protein         1..107
                     /product="thioredoxin b"
                     /note="thioredoxin"
                     /calculated_mol_wt=12285
     Region          10..102
                     /region_name="TRX_family"
                     /note="TRX family; composed of two groups: Group I, which
                     includes proteins that exclusively encode a TRX domain;
                     and Group II, which are composed of fusion proteins of TRX
                     and additional domains. Group I TRX is a small ancient
                     protein that alter the redox...; cd02947"
                     /db_xref="CDD:239245"
     Site            order(32,35)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239245"
     CDS             1..107
                     /gene="txnb"
                     /gene_synonym="trx1; txn"
                     /coded_by="NM_001294226.1:24..347"
                     /db_xref="GeneID:103388327"
ORIGIN      
        1 mvyevkdynd ftqqlkragn klvvvdftat wcqpcknisp vfeelanqyk nvvflkvdvd
       61 eaddvstece incmptflfy rnekrvhsfs gansdtlraa vkqyeke
//
LOCUS       NP_001428429             759 aa            linear   ROD 19-JUN-2025
DEFINITION  transmembrane channel-like protein 1 isoform 1 [Rattus norvegicus].
ACCESSION   NP_001428429
VERSION     NP_001428429.1
DBSOURCE    REFSEQ: accession NM_001441500.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 759)
  AUTHORS   Beurg,M., Kim,K.X. and Fettiplace,R.
  TITLE     Conductance and block of hair-cell mechanotransducer channels in
            transmembrane channel-like protein mutants
  JOURNAL   J Gen Physiol 144 (1), 55-69 (2014)
   PUBMED   24981230
REFERENCE   2  (residues 1 to 759)
  AUTHORS   Pan,B., Geleoc,G.S., Asai,Y., Horwitz,G.C., Kurima,K., Ishikawa,K.,
            Kawashima,Y., Griffith,A.J. and Holt,J.R.
  TITLE     TMC1 and TMC2 are components of the mechanotransduction channel in
            hair cells of the mammalian inner ear
  JOURNAL   Neuron 79 (3), 504-515 (2013)
   PUBMED   23871232
REFERENCE   3  (residues 1 to 759)
  AUTHORS   Kawashima,Y., Geleoc,G.S., Kurima,K., Labay,V., Lelli,A., Asai,Y.,
            Makishima,T., Wu,D.K., Della Santina,C.C., Holt,J.R. and
            Griffith,A.J.
  TITLE     Mechanotransduction in mouse inner ear hair cells requires
            transmembrane channel-like genes
  JOURNAL   J Clin Invest 121 (12), 4796-4809 (2011)
   PUBMED   22105175
REFERENCE   4  (residues 1 to 759)
  AUTHORS   Takayanagi,S., Hiroyama,T., Yamazaki,S., Nakajima,T., Morita,Y.,
            Usui,J., Eto,K., Motohashi,T., Shiomi,K., Keino-Masu,K., Masu,M.,
            Oike,Y., Mori,S., Yoshida,N., Iwama,A. and Nakauchi,H.
  TITLE     Genetic marking of hematopoietic stem and endothelial cells:
            identification of the Tmtsp gene encoding a novel cell surface
            protein with the thrombospondin-1 domain
  JOURNAL   Blood 107 (11), 4317-4325 (2006)
   PUBMED   16455951
REFERENCE   5  (residues 1 to 759)
  AUTHORS   Kurima,K., Peters,L.M., Yang,Y., Riazuddin,S., Ahmed,Z.M., Naz,S.,
            Arnaud,D., Drury,S., Mo,J., Makishima,T., Ghosh,M., Menon,P.S.,
            Deshmukh,D., Oddoux,C., Ostrer,H., Khan,S., Riazuddin,S.,
            Deininger,P.L., Hampton,L.L., Sullivan,S.L., Battey,J.F. Jr.,
            Keats,B.J., Wilcox,E.R., Friedman,T.B. and Griffith,A.J.
  TITLE     Dominant and recessive deafness caused by mutations of a novel
            gene, TMC1, required for cochlear hair-cell function
  JOURNAL   Nat Genet 30 (3), 277-284 (2002)
   PUBMED   11850618
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760389
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q51"
     Protein         1..759
                     /product="transmembrane channel-like protein 1 isoform 1"
                     /note="transmembrane channel-like protein 1; transmembrane
                     channel-like gene family 1"
                     /calculated_mol_wt=87324
     CDS             1..759
                     /gene="Tmc1"
                     /coded_by="NM_001441500.1:102..2381"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="GeneID:361739"
                     /db_xref="RGD:1308682"
ORIGIN      
        1 mppkkvqiqv egkeddtdas sseeeeedkl prreslrpkr krtrdvined dpepepedee
       61 trkarekerr rrlrrgaeee eeideeeler lkalldenrq miatvkckpw kmekkievlk
      121 eakkfvsene galgkgkgkk wfafkmmmak kwakflrdfe nfkaacvpwe nkikaiesqf
      181 gssvasyflf lrwmygvnmv lfiltfslim lpeylwglpy gslprktvpr aeeasaanfg
      241 vlydfnglaq ysvlfygyyd nkrtigwlnf rlplsyflvg imcigysflv vlkamtknig
      301 ddgggddntf nfswkvfcsw dylignpeta dnkfnsitmn fkeaiieera aqveenihli
      361 rflrflanff vfltlgasgy lifwavkrsq efaqqdpdtl gwweknemnm vmsllgmfcp
      421 tlfdlfaele dyhplialkw llgrifalll gnlyvfilal mdeinnkiee eklvkanitl
      481 weanmikayn eslsgnttgp pffvhpadvp rgpcwetmvg qefvrltvsd vlttyvtili
      541 gdflracfvr fcnycwcwdl eygypsytef disgnvlali fnqgmiwmgs ffapslpgin
      601 ilrlhtsmyf qcwavmccnv pearvfkasr snnfylgmll lilflstmpv lymivslpps
      661 fdcgpfsgkn rmfevigetl ehdfpswmak ilrqlsnpgl viavilvmvl tiyylnatak
      721 gqkaanldlk kkmkqqalen kmrnkkmaaa raaaaaggq
//
LOCUS       NP_001315174             422 aa            linear   VRT 19-JUN-2025
DEFINITION  bone morphogenetic protein 2b precursor [Cynoglossus semilaevis].
ACCESSION   NP_001315174 XP_008311457
VERSION     NP_001315174.1
DBSOURCE    REFSEQ: accession NM_001328245.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from KC422338.1.
            
            On Jun 9, 2016 this sequence version replaced XP_008311457.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: KC422338.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN03753709
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="7"
                     /map="7"
     Protein         1..422
                     /product="bone morphogenetic protein 2b precursor"
                     /note="bone morphogenetic protein 2"
                     /calculated_mol_wt=45205
     sig_peptide     1..23
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2354
     Region          48..289
                     /region_name="TGFb_propeptide"
                     /note="TGF-beta propeptide; pfam00688"
                     /db_xref="CDD:459906"
     Region          322..422
                     /region_name="TGF_beta_BMP2_like"
                     /note="transforming growth factor beta (TGF-beta) like
                     domain found in bone morphogenetic protein 2 (BMP-2), 4
                     (BMP-4) and similar proteins; cd13760"
                     /db_xref="CDD:381638"
     Site            order(327,329,333..334,336,346,348..350,367..368,371..372,
                     374..375,378,381..383,386,388..389,392,412..414,416,422)
                     /site_type="other"
                     /note="putative homodimer interface [polypeptide binding]"
                     /db_xref="CDD:381638"
     CDS             1..422
                     /gene="bmp2b"
                     /gene_synonym="bmp2"
                     /coded_by="NM_001328245.1:443..1711"
                     /db_xref="GeneID:103381057"
ORIGIN      
        1 mvavvrslmv lllaqvlleg aaglipdvgr rkysesgkqs peqsesflnd felrllnmfg
       61 lrrrptpskh avvpqymvdl yrmhsangdh stkrpksmgk haeraaskan tirsfhhees
      121 mealaslkgk ttqqfffnlt sipdeelits aelriyrdqv tgeahpnnss rnssssssgs
      181 agglhqiniy eifgapasqn getlarlldt rlvqdslsrw esfdvspavs qwtsgkrhnh
      241 gfmvevfhph qgeveerhaq krsrhvrvsr slhqdqdswp qarpllvtys hdgrgdsvlh
      301 trekrqatlr knrrkqqhka scrrhdlyvd fsdvgwnewi vappgyhafy chgecpfpla
      361 dhlnstnhai vqtlvnsvns nipkaccvpt dlsaisllyl dengkvilkn yqdmvvegcg
      421 cr
//
LOCUS       NP_001284511             312 aa            linear   VRT 19-JUN-2025
DEFINITION  zona pellucida glycoprotein 3f, tandem duplicate 1 precursor
            [Cynoglossus semilaevis].
ACCESSION   NP_001284511 XP_008332969
VERSION     NP_001284511.2
DBSOURCE    REFSEQ: accession NM_001297582.2
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
REFERENCE   1  (residues 1 to 312)
  AUTHORS   Sun,Y., Yu,H., Zhang,Q., Qi,J., Zhong,Q., Chen,Y. and Li,C.
  TITLE     Molecular characterization and expression pattern of two zona
            pellucida genes in half-smooth tongue sole (Cynoglossus semilaevis)
  JOURNAL   Comp Biochem Physiol B Biochem Mol Biol 155 (3), 316-321 (2010)
   PUBMED   20135848
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AGRG01018760.1.
            
            On Sep 12, 2018 this sequence version replaced NP_001284511.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU399872.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00752404, SAMN03753709
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="20"
                     /map="20"
     Protein         1..312
                     /product="zona pellucida glycoprotein 3f, tandem duplicate
                     1 precursor"
                     /calculated_mol_wt=32268
     sig_peptide     1..22
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2519
     Region          28..257
                     /region_name="Zona_pellucida"
                     /note="Zona pellucida-like domain; pfam00100"
                     /db_xref="CDD:459673"
     CDS             1..312
                     /gene="zp3f.1"
                     /gene_synonym="ZPC1"
                     /coded_by="NM_001297582.2:11..949"
                     /db_xref="GeneID:103396601"
ORIGIN      
        1 mmafsrqcvl ffcllaafsv yadmrldcrp dfvtlvwtes rihvdpsllr lgscfptsvt
       61 ameavfsvdl ndcnfdrlvt gdqmiytndl tyisshesfs hpvvcvydrp kdwfpliydp
      121 vfnthgeagl vfhaglmndd fsgpavsntf plgssipvma sveeathqpl lllleeclaa
      181 dtpqlvpesn vytvignkgc lvdsrvsrsr feprikssei kvslqafrfa lgkevfihck
      241 llawdpmgld ntkkachyvk dhgwelldnp aysnlcdccd sscksrktrs igsgelglrh
      301 kavigpltit et
//
LOCUS       NP_001232401             243 aa            linear   VRT 19-JUN-2025
DEFINITION  non-structural maintenance of chromosomes element 1 homolog
            [Taeniopygia guttata].
ACCESSION   NP_001232401 XP_002198117 XP_002198123 XP_002198126
VERSION     NP_001232401.1
DBSOURCE    REFSEQ: accession NM_001245472.1
KEYWORDS    RefSeq.
SOURCE      Taeniopygia guttata (zebra finch)
  ORGANISM  Taeniopygia guttata
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
            Passeriformes; Passeroidea; Estrildidae; Estrildinae; Taeniopygia.
REFERENCE   1  (residues 1 to 243)
  AUTHORS   Wada,K., Howard,J.T., McConnell,P., Whitney,O., Lints,T.,
            Rivas,M.V., Horita,H., Patterson,M.A., White,S.A., Scharff,C.,
            Haesler,S., Zhao,S., Sakaguchi,H., Hagiwara,M., Shiraki,T.,
            Hirozane-Kishikawa,T., Skene,P., Hayashizaki,Y., Carninci,P. and
            Jarvis,E.D.
  TITLE     A molecular neuroethological approach for identifying and
            characterizing a cascade of behaviorally regulated genes
  JOURNAL   Proc Natl Acad Sci U S A 103 (41), 15212-15217 (2006)
   PUBMED   17018643
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):17064]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EF191932.1.
            
            On or before Oct 10, 2011 this sequence version replaced
            XP_002198126.1, XP_002198123.1, XP_002198117.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF191932.1, DQ214048.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00179581, SAMN17710057
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..243
                     /organism="Taeniopygia guttata"
                     /db_xref="taxon:59729"
                     /chromosome="14"
                     /map="14"
     Protein         1..243
                     /product="non-structural maintenance of chromosomes
                     element 1 homolog"
                     /EC_number="2.3.2.27"
                     /note="putative non-structural maintenance of chromosomes
                     element 1 protein; non-structural maintenance of
                     chromosomes element 1 protein-like; NSE1 homolog,
                     SMC5-SMC6 complex component"
                     /calculated_mol_wt=27622
     Region          10..169
                     /region_name="SMC_Nse1"
                     /note="Nse1 non-SMC component of SMC5-6 complex;
                     pfam07574"
                     /db_xref="CDD:462214"
     Region          183..229
                     /region_name="RING-CH-C4HC3_NSE1"
                     /note="RING-CH finger, H2 subclass (C4HC3-type), found in
                     non-structural maintenance of chromosomes (SMC) element 1
                     homolog (NSE1) and similar proteins; cd16493"
                     /db_xref="CDD:438156"
     CDS             1..243
                     /gene="NSMCE1"
                     /coded_by="NM_001245472.1:148..879"
                     /db_xref="GeneID:100190587"
ORIGIN      
        1 maaqmtnahr rflqalmsng itegseakkl hqhccetdkv yyahdklddf istinshlqp
       61 lfmqirkgis eddgrahyav vnlaetevtk masdytesel elfrktmdli ilsengfass
      121 tdilnladql ktkkmkkkea eqvlkvfved kwlsekngey tlhtrciiem eqyilsnyqd
      181 varkcnichs laiqsqgces cgigmhlpcv rkyfrgqtep rcpecnefws cdtpgvsrmg
      241 sqt
//
LOCUS       NP_065184                590 aa            linear   PRI 19-JUN-2025
DEFINITION  selenoprotein N isoform 2 [Homo sapiens].
ACCESSION   NP_065184
VERSION     NP_065184.2
DBSOURCE    REFSEQ: accession NM_020451.3
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 590)
  AUTHORS   Castets,P., Lescure,A., Guicheney,P. and Allamand,V.
  TITLE     Selenoprotein N in skeletal muscle: from diseases to function
  JOURNAL   J Mol Med (Berl) 90 (10), 1095-1107 (2012)
   PUBMED   22527882
  REMARK    GeneRIF: The physiological function of SelN in muscle tissue and
            the pathogenesis leading to SEPN1-related myopathies. [Review]
            Review article
REFERENCE   2  (residues 1 to 590)
  AUTHORS   Maiti,B., Arbogast,S., Allamand,V., Moyle,M.W., Anderson,C.B.,
            Richard,P., Guicheney,P., Ferreiro,A., Flanigan,K.M. and
            Howard,M.T.
  TITLE     A mutation in the SEPN1 selenocysteine redefinition element (SRE)
            reduces selenocysteine incorporation and leads to SEPN1-related
            myopathy
  JOURNAL   Hum Mutat 30 (3), 411-416 (2009)
   PUBMED   19067361
  REMARK    GeneRIF: Data highlights the importance of the SRE element during
            SelN expression and illustrates a novel molecular mechanism by
            which point mutations may lead to SEPN1-related myopathy.
REFERENCE   3  (residues 1 to 590)
  AUTHORS   Allamand,V., Richard,P., Lescure,A., Ledeuil,C., Desjardin,D.,
            Petit,N., Gartioux,C., Ferreiro,A., Krol,A., Pellegrini,N.,
            Urtizberea,J.A. and Guicheney,P.
  TITLE     A single homozygous point mutation in a 3'untranslated region motif
            of selenoprotein N mRNA causes SEPN1-related myopathy
  JOURNAL   EMBO Rep 7 (4), 450-454 (2006)
   PUBMED   16498447
  REMARK    GeneRIF: identification of this mutation affecting a conserved base
            in the selenocysteine insertion sequence functional motif thereby
            reveals the structural basis for a novel pathological mechanism
            leading to SEPN1-related myopathy
REFERENCE   4  (residues 1 to 590)
  AUTHORS   Howard,M.T., Aggarwal,G., Anderson,C.B., Khatri,S., Flanigan,K.M.
            and Atkins,J.F.
  TITLE     Recoding elements located adjacent to a subset of eukaryal
            selenocysteine-specifying UGA codons
  JOURNAL   EMBO J 24 (8), 1596-1607 (2005)
   PUBMED   15791204
REFERENCE   5  (residues 1 to 590)
  AUTHORS   Petit,N., Lescure,A., Rederstorff,M., Krol,A., Moghadaszadeh,B.,
            Wewer,U.M. and Guicheney,P.
  TITLE     Selenoprotein N: an endoplasmic reticulum glycoprotein with an
            early developmental expression pattern
  JOURNAL   Hum Mol Genet 12 (9), 1045-1053 (2003)
   PUBMED   12700173
REFERENCE   6  (residues 1 to 590)
  AUTHORS   Moghadaszadeh,B., Petit,N., Jaillard,C., Brockington,M., Quijano
            Roy,S., Merlini,L., Romero,N., Estournet,B., Desguerre,I.,
            Chaigne,D., Muntoni,F., Topaloglu,H. and Guicheney,P.
  TITLE     Mutations in SEPN1 cause congenital muscular dystrophy with spinal
            rigidity and restrictive respiratory syndrome
  JOURNAL   Nat Genet 29 (1), 17-18 (2001)
   PUBMED   11528383
REFERENCE   7  (residues 1 to 590)
  AUTHORS   Lescure,A., Gautheret,D., Carbon,P. and Krol,A.
  TITLE     Novel selenoproteins identified in silico and in vivo by using a
            conserved RNA structural motif
  JOURNAL   J Biol Chem 274 (53), 38147-38154 (1999)
   PUBMED   10608886
REFERENCE   8  (residues 1 to 590)
  AUTHORS   Sparks,S.E., Quijano-Roy,S., Harper,A., Rutkowski,A., Gordon,E.,
            Hoffman,E.P. and Pegoraro,E.
  TITLE     Congenital Muscular Dystrophy Overview - RETIRED CHAPTER, FOR
            HISTORICAL REFERENCE ONLY
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301468
REFERENCE   9  (residues 1 to 590)
  AUTHORS   Beggs,A.H. and Agrawal,P.B.
  TITLE     Multiminicore Disease - RETIRED CHAPTER, FOR HISTORICAL REFERENCE
            ONLY
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301467
REFERENCE   10 (residues 1 to 590)
  AUTHORS   DeChene,E.T., Kang,P.B. and Beggs,A.H.
  TITLE     Congenital Fiber-Type Disproportion - RETIRED CHAPTER, FOR
            HISTORICAL REFERENCE ONLY
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301436
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AJ306399.1, AA613025.1,
            BQ217758.1 and BC021028.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 24, 2004 this sequence version replaced NP_065184.1.
            
            Summary: This gene encodes a glycoprotein that is localized in the
            endoplasmic reticulum. It plays an important role in cell
            protection against oxidative stress, and in the regulation of
            redox-related calcium homeostasis. Mutations in this gene are
            associated with early onset muscle disorders, referred to as
            SEPN1-related myopathy. SEPN1-related myopathy consists of 4
            autosomal recessive disorders, originally thought to be separate
            entities: rigid spine muscular dystrophy (RSMD1), the classical
            form of multiminicore disease, desmin related myopathy with
            Mallory-body like inclusions, and congenital fiber-type
            disproportion (CFTD). This protein is a selenoprotein, containing
            the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA
            codon, which normally signals translation termination. The 3' UTRs
            of selenoprotein mRNAs contain a conserved stem-loop structure,
            designated the Sec insertion sequence (SECIS) element, that is
            necessary for the recognition of UGA as a Sec codon, rather than as
            a stop signal. A second stop-codon redefinition element (SRE)
            adjacent to the UGA codon has been identified in this gene
            (PMID:15791204). SRE is a phylogenetically conserved stem-loop
            structure that stimulates readthrough at the UGA codon, and
            augments the Sec insertion efficiency by SECIS. Alternatively
            spliced transcript variants have been found for this gene.
            [provided by RefSeq, Dec 2016].
            
            Transcript Variant: This variant (2) contains an additional
            in-frame, Alu-derived coding exon in the 5' region compared to
            variant 1. The encoded isoform (2) is longer than isoform 1,
            containing two potential selenocysteine (Sec) residues. The first
            Sec found in the novel exon is not conserved, while the second Sec
            is highly conserved. Expression of isoform 2 was not detected in
            vivo or in transfection studies, leaving open the possibility that
            the UGA codon in the novel exon may be recognized as a stop codon,
            and not as a Sec codon (PMID:12700173).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ306399.1, DRR138518.258546.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            protein contains selenocysteine :: PMID: 10608886
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     Protein         1..590
                     /product="selenoprotein N isoform 2"
                     /note="selenoprotein N, 1"
                     /calculated_mol_wt=65682
     Site            127
                     /site_type="other"
                     /note="Selenocysteine"
     Site            462
                     /site_type="other"
                     /note="Selenocysteine"
     CDS             1..590
                     /gene="SELENON"
                     /gene_synonym="CFTD; CMYO3; CMYP3; MDRS1; RSMD1; RSS;
                     SELN; SEPN1"
                     /coded_by="NM_020451.3:39..1811"
                     /note="UGA stop codons recoded as selenocysteine; isoform
                     2 is encoded by transcript variant 2"
                     /db_xref="CCDS:CCDS41282.1"
                     /db_xref="GeneID:57190"
                     /db_xref="HGNC:HGNC:15999"
                     /db_xref="MIM:606210"
ORIGIN      
        1 mgrarpgqrg ppspgpaaqp papprrrars lallgallaa aaaaavrvca rhaeaqaaar
       61 qelalktlgt dglflfssld tdgdmyispe efkpiaeklt gscsvtqtgv qwcshsslqp
      121 qlpwlnussc lsllrstpaa sceeeelppd pseetltiea rfqpllpetm tkskdgflgv
      181 srlalsglrn wtaaaspsav fatrhfqpfl pppgqelgep wwiipselsm ftgylsnnrf
      241 yppppkgkev iihrllsmfh prpfvktrfa pqgavaclta isdfyytvmf rihaefqlse
      301 ppdfpfwfsp aqftghiils kdathvrdfr lfvpnhrsln vdmewlygas essnmevdig
      361 yipqmeleat gpsvpsvild edgsmidshl psgeplqfvf eeikwqqels weeaarrlev
      421 amypfkkvsy lpfteafdra kaenklvhsi llwgalddqs cugsgrtlre tvlesspilt
      481 llnesfistw slvkeleelq nnqensshqk laglhlekys fpvemmiclp ngtvvhhina
      541 nyflditsvk peeiesnlfs fsstfedpst atymqflkeg lrrglpllqp
//
LOCUS       NP_001016129             502 aa            linear   VRT 19-JUN-2025
DEFINITION  aldehyde dehydrogenase 3 family member B4 [Xenopus tropicalis].
ACCESSION   NP_001016129
VERSION     NP_001016129.1
DBSOURCE    REFSEQ: accession NM_001016129.2
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (residues 1 to 502)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CR762057.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR762057.2, BC170900.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028305, SAMN04272115
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Xenopus tropicalis"
                     /db_xref="taxon:8364"
                     /chromosome="1"
                     /map="1"
     Protein         1..502
                     /product="aldehyde dehydrogenase 3 family member B4"
                     /EC_number="1.2.1.5"
                     /note="aldehyde dehydrogenase 3 family member B1"
                     /calculated_mol_wt=55796
     Region          37..479
                     /region_name="ALDH-SF"
                     /note="NAD(P)+-dependent aldehyde dehydrogenase
                     superfamily; cl11961"
                     /db_xref="CDD:448367"
     Site            order(143..147,155,170,172..173,218..221,224,227..228,
                     242..244,276,366,368,394,434)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:143395"
     Site            order(147,242,273,276)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143395"
     CDS             1..502
                     /gene="aldh3b4"
                     /gene_synonym="aldh3b1; aldh4; aldh7"
                     /coded_by="NM_001016129.2:92..1600"
                     /db_xref="GeneID:548883"
                     /db_xref="Xenbase:XB-GENE-5749635"
ORIGIN      
        1 mdnvksspsp arwfrvlkrt vsgdcqqkkf vtpslcedal rkcreafssg ktrpcsfrsl
       61 qleailnmld kheeefigal eqdmhrprfe tilseinsvk nealyalnnl ekwtqpvpgq
      121 ksmsnlldsc fiqmepvgvv liisgwsfpi qlsliplvga vaagncvvlq psgtcthaan
      181 llqrliplyl dnscyhvacg gqnelmklle nkfdhilytg drltgravml aaakyitpvs
      241 lvlggknpcy vdnscdinma arriawarfv nagqsslapd yilcqpeird tlihelsicv
      301 eefygknpre ssnygrlasv elylqvkdll scgqvafgge tddseryiap tvltdvkead
      361 pimqteilgp vlpiltvenl deaiqminrk drplavyvys eservisdil crtssgsfcs
      421 ndsmiqsiyt smpcgiigns gigiyrgkhc feafsqsrac llrntavecv tylryppyae
      481 kplrlllwac sisrkkslch il
//
LOCUS       NP_001088478             778 aa            linear   VRT 19-JUN-2025
DEFINITION  EMAP like 1 S homeolog [Xenopus laevis].
ACCESSION   NP_001088478
VERSION     NP_001088478.1
DBSOURCE    REFSEQ: accession NM_001095009.1
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (residues 1 to 778)
  AUTHORS   Klein,S.L., Strausberg,R.L., Wagner,L., Pontius,J., Clifton,S.W.
            and Richardson,P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC084807.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC084807.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00012419, SAMN04111048
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..778
                     /organism="Xenopus laevis"
                     /db_xref="taxon:8355"
                     /chromosome="8S"
                     /map="8S"
     Protein         1..778
                     /product="EMAP like 1 S homeolog"
                     /note="echinoderm microtubule associated protein like 1 S
                     homeolog"
                     /calculated_mol_wt=85424
     Region          1..48
                     /region_name="TD_EMAP2"
                     /note="trimerization domain of echinoderm
                     microtubule-associated protein-like 2; cd21948"
                     /db_xref="CDD:409269"
     Site            order(3..4,6..7,10..11,13..14,17..18,20..21,24..25,27..28,
                     31..32,34..36,38..39,41)
                     /site_type="other"
                     /note="trimer interface [polypeptide binding]"
                     /db_xref="CDD:409269"
     Region          140..211
                     /region_name="HELP"
                     /note="HELP motif; pfam03451"
                     /db_xref="CDD:460922"
     Region          184..221
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          226..272
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          281..323
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          300..666
                     /region_name="WD40"
                     /note="WD40 repeat [General function prediction only];
                     COG2319"
                     /db_xref="CDD:441893"
     Region          330..375
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          384..419
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          425..495
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          510..545
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          552..584
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          592..632
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          638..662
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          705..742
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     CDS             1..778
                     /gene="eml1.S"
                     /gene_synonym="eml1"
                     /coded_by="NM_001095009.1:159..2495"
                     /db_xref="GeneID:495344"
                     /db_xref="Xenbase:XB-GENE-949784"
ORIGIN      
        1 mdtddrisnl eqrlqlqede mqvlraalsd alrrlrvcee rgdairgrqs vhivkppprp
       61 vqngtaprrr iglstspssp kmggtpvfak svrralsper msflkrdisd trsrvlascs
      121 grrdgkskqv vfypeegvvk lylrgravpl yvpdslvasy tpdakgelpt relqlewvyg
      181 yrgrdcrsnl fvlpsgelly ftaavcvlyd paagtqrhyr ghtddikslt vhpdsvtias
      241 gqvagnsqdg kalpphvriw hsvslctlhv lgvgsferav tclsfsktdg gsllcacdes
      301 gdhvlsvwqw qretkmaevk cstepvlati fhptepnlii tcgksqlyyw slegatgggs
      361 tsggatlskr qgvfekyekp rfvlcvafae ngdvitgdsn gnlfvwgkgs hrishavsna
      421 hdgsifalcv crdgtilsgg gkdgrvilwn rdyrkvqetr ipecfgpvrt iaegrggetl
      481 yvgttkncvm sgnlesglsc liqghtdelw glcthpildl fltcghdkfv hlwnskehqp
      541 vwsttledaa rvagfhpsgs vvaigtssgr flvldsqthv ivtsisdaae qisvtryspd
      601 ghylavgshd nfiylyeved egreyrrvgk ctghssfvth ldwasdsscf mtnsgdyeil
      661 ywdpdsckqi vsaenirnid wenssctlgf yvlgiwpdga dgtdinavtr shdrkllatg
      721 ddfggvrlyn ypcvvprass hkycghsshv trvvflhnds vmlsaggkds tvlqwavl
//
LOCUS       NP_001281128             307 aa            linear   VRT 19-JUN-2025
DEFINITION  forkhead box protein L2a [Cynoglossus semilaevis].
ACCESSION   NP_001281128 XP_008307586
VERSION     NP_001281128.1
DBSOURCE    REFSEQ: accession NM_001294199.1
KEYWORDS    RefSeq.
SOURCE      Cynoglossus semilaevis (tongue sole)
  ORGANISM  Cynoglossus semilaevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei;
            Cynoglossidae; Cynoglossinae; Cynoglossus.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from GQ402462.1.
            
            On Jun 26, 2014 this sequence version replaced XP_008307586.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: GQ402462.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Cynoglossus semilaevis"
                     /db_xref="taxon:244447"
                     /chromosome="4"
                     /map="4"
     Protein         1..307
                     /product="forkhead box protein L2a"
                     /note="forkhead box transcription factor Foxl2; forkhead
                     box L2"
                     /calculated_mol_wt=34471
     Region          48..136
                     /region_name="FH_FOXL2"
                     /note="Forkhead (FH) domain found in Forkhead box protein
                     L2 (FOXL2) and similar proteins; cd20028"
                     /db_xref="CDD:410802"
     Site            order(53,71..72,75,94..95,97..98,101,108,118..120,122)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:410802"
     CDS             1..307
                     /gene="foxl2a"
                     /gene_synonym="foxl2"
                     /coded_by="NM_001294199.1:269..1192"
                     /db_xref="GeneID:103378228"
ORIGIN      
        1 mmaayrsaeg demaliihds nannkekerp keepvqekvc ekpdptqkpp ysyvaliama
       61 iressekrlt lsgiyqyiis kfpfyeknkk gwqnsirhnl slnecfikvp regggerkgn
      121 ywtldpaced mfekgnyrrr rrmkrpfrpp pthfqpgksl fgtdsygyls ppkylqssfm
      181 nnswslsqpp apisytscqm asgnvspvnm kglsppssyn pysrvqsmal pgmvnsyngm
      241 shhhhpvhph pgqqlssaaa gppsvsssng aglqfacsrq paelsmmhcs ywdheskhsa
      301 lhtridi
//
