1 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 1 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 1 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 1 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 1 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 1 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 1 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 1 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 1 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 1 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 100 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 100 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 100 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 100 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 100 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 100 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 100 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 100 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 100 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 100 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 100 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 100 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 100 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 100 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 100 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 100 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 100 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 100 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 10002 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 10002 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 10002 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 10002 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 10002 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 10002 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 10002 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 10002 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 10002 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 10002 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 10002 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 10002 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 10002 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 10002 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 10002 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 10002 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 10002 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 10002 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 10002 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 10002 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 10010 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 10010 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 10010 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 10010 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 10010 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 10010 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 10010 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 10010 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 10010 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 10010 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 10090 R-BTA-388828 https://reactome.org/PathwayBrowser/#/R-BTA-388828 PD-1 binds B7DC and B7H1 IEA Bos taurus 10090 R-BTA-9679421 https://reactome.org/PathwayBrowser/#/R-BTA-9679421 PDCD1 binds PDCD1 inhibitors IEA Bos taurus 10090 R-BTA-9936162 https://reactome.org/PathwayBrowser/#/R-BTA-9936162 PD-1 binds PD-L1,PD-L2 IEA Bos taurus 10090 R-CFA-388828 https://reactome.org/PathwayBrowser/#/R-CFA-388828 PD-1 binds B7DC and B7H1 IEA Canis familiaris 10090 R-CFA-9679421 https://reactome.org/PathwayBrowser/#/R-CFA-9679421 PDCD1 binds PDCD1 inhibitors IEA Canis familiaris 10090 R-CFA-9936162 https://reactome.org/PathwayBrowser/#/R-CFA-9936162 PD-1 binds PD-L1,PD-L2 IEA Canis familiaris 10090 R-GGA-388828 https://reactome.org/PathwayBrowser/#/R-GGA-388828 PD-1 binds B7DC and B7H1 IEA Gallus gallus 10090 R-GGA-9679421 https://reactome.org/PathwayBrowser/#/R-GGA-9679421 PDCD1 binds PDCD1 inhibitors IEA Gallus gallus 10090 R-GGA-9936162 https://reactome.org/PathwayBrowser/#/R-GGA-9936162 PD-1 binds PD-L1,PD-L2 IEA Gallus gallus 10090 R-HSA-388828 https://reactome.org/PathwayBrowser/#/R-HSA-388828 PD-1 binds B7DC and B7H1 TAS Homo sapiens 10090 R-HSA-9679421 https://reactome.org/PathwayBrowser/#/R-HSA-9679421 PDCD1 binds PDCD1 inhibitors TAS Homo sapiens 10090 R-HSA-9936162 https://reactome.org/PathwayBrowser/#/R-HSA-9936162 PD-1 binds PD-L1,PD-L2 TAS Homo sapiens 10090 R-MMU-388828 https://reactome.org/PathwayBrowser/#/R-MMU-388828 PD-1 binds B7DC and B7H1 IEA Mus musculus 10090 R-MMU-9679421 https://reactome.org/PathwayBrowser/#/R-MMU-9679421 PDCD1 binds PDCD1 inhibitors IEA Mus musculus 10090 R-MMU-9936162 https://reactome.org/PathwayBrowser/#/R-MMU-9936162 PD-1 binds PD-L1,PD-L2 IEA Mus musculus 10090 R-RNO-388828 https://reactome.org/PathwayBrowser/#/R-RNO-388828 PD-1 binds B7DC and B7H1 IEA Rattus norvegicus 10090 R-RNO-9679421 https://reactome.org/PathwayBrowser/#/R-RNO-9679421 PDCD1 binds PDCD1 inhibitors IEA Rattus norvegicus 10090 R-RNO-9936162 https://reactome.org/PathwayBrowser/#/R-RNO-9936162 PD-1 binds PD-L1,PD-L2 IEA Rattus norvegicus 10090 R-SSC-388828 https://reactome.org/PathwayBrowser/#/R-SSC-388828 PD-1 binds B7DC and B7H1 IEA Sus scrofa 10090 R-SSC-9679421 https://reactome.org/PathwayBrowser/#/R-SSC-9679421 PDCD1 binds PDCD1 inhibitors IEA Sus scrofa 10090 R-SSC-9936162 https://reactome.org/PathwayBrowser/#/R-SSC-9936162 PD-1 binds PD-L1,PD-L2 IEA Sus scrofa 10100 R-BTA-9611839 https://reactome.org/PathwayBrowser/#/R-BTA-9611839 β3-agonists bind ADRB3 IEA Bos taurus 10100 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 10100 R-CFA-9611839 https://reactome.org/PathwayBrowser/#/R-CFA-9611839 β3-agonists bind ADRB3 IEA Canis familiaris 10100 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 10100 R-DME-9611839 https://reactome.org/PathwayBrowser/#/R-DME-9611839 β3-agonists bind ADRB3 IEA Drosophila melanogaster 10100 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 10100 R-GGA-9611839 https://reactome.org/PathwayBrowser/#/R-GGA-9611839 β3-agonists bind ADRB3 IEA Gallus gallus 10100 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 10100 R-HSA-9611839 https://reactome.org/PathwayBrowser/#/R-HSA-9611839 β3-agonists bind ADRB3 TAS Homo sapiens 10100 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 10100 R-MMU-9611839 https://reactome.org/PathwayBrowser/#/R-MMU-9611839 β3-agonists bind ADRB3 IEA Mus musculus 10100 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 10100 R-RNO-9611839 https://reactome.org/PathwayBrowser/#/R-RNO-9611839 β3-agonists bind ADRB3 IEA Rattus norvegicus 10100 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 10100 R-SSC-9611839 https://reactome.org/PathwayBrowser/#/R-SSC-9611839 β3-agonists bind ADRB3 IEA Sus scrofa 10100 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 10102 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 10102 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 10102 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 10102 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 10102 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 10102 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 10102 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 10102 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 10103 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 10103 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 10103 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 10103 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 10103 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 10103 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 10103 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 10103 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 10129 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 10129 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 10129 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 10129 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 10129 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 10129 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 10129 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 10129 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 10129 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 10129 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 10129 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 1013 R-BTA-176521 https://reactome.org/PathwayBrowser/#/R-BTA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Bos taurus 1013 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 1013 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 1013 R-BTA-5693390 https://reactome.org/PathwayBrowser/#/R-BTA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Bos taurus 1013 R-BTA-5696822 https://reactome.org/PathwayBrowser/#/R-BTA-5696822 AKR1B15 reduces EST17b to E1 IEA Bos taurus 1013 R-BTA-6810594 https://reactome.org/PathwayBrowser/#/R-BTA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 1013 R-BTA-804969 https://reactome.org/PathwayBrowser/#/R-BTA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Bos taurus 1013 R-BTA-8862137 https://reactome.org/PathwayBrowser/#/R-BTA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 1013 R-BTA-9008258 https://reactome.org/PathwayBrowser/#/R-BTA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Bos taurus 1013 R-BTA-9008270 https://reactome.org/PathwayBrowser/#/R-BTA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Bos taurus 1013 R-BTA-9008271 https://reactome.org/PathwayBrowser/#/R-BTA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Bos taurus 1013 R-BTA-9008285 https://reactome.org/PathwayBrowser/#/R-BTA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Bos taurus 1013 R-BTA-9009526 https://reactome.org/PathwayBrowser/#/R-BTA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 1013 R-BTA-9009533 https://reactome.org/PathwayBrowser/#/R-BTA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Bos taurus 1013 R-BTA-9009536 https://reactome.org/PathwayBrowser/#/R-BTA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Bos taurus 1013 R-BTA-9009541 https://reactome.org/PathwayBrowser/#/R-BTA-9009541 ESR1 binds to TFF1 gene promoter IEA Bos taurus 1013 R-BTA-9023860 https://reactome.org/PathwayBrowser/#/R-BTA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Bos taurus 1013 R-BTA-9023861 https://reactome.org/PathwayBrowser/#/R-BTA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 1013 R-BTA-9023884 https://reactome.org/PathwayBrowser/#/R-BTA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Bos taurus 1013 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 1013 R-CEL-5696822 https://reactome.org/PathwayBrowser/#/R-CEL-5696822 AKR1B15 reduces EST17b to E1 IEA Caenorhabditis elegans 1013 R-CFA-176521 https://reactome.org/PathwayBrowser/#/R-CFA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Canis familiaris 1013 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 1013 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 1013 R-CFA-5693390 https://reactome.org/PathwayBrowser/#/R-CFA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Canis familiaris 1013 R-CFA-804969 https://reactome.org/PathwayBrowser/#/R-CFA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Canis familiaris 1013 R-CFA-8862137 https://reactome.org/PathwayBrowser/#/R-CFA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Canis familiaris 1013 R-CFA-9008258 https://reactome.org/PathwayBrowser/#/R-CFA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Canis familiaris 1013 R-CFA-9008270 https://reactome.org/PathwayBrowser/#/R-CFA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Canis familiaris 1013 R-CFA-9008271 https://reactome.org/PathwayBrowser/#/R-CFA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Canis familiaris 1013 R-CFA-9008285 https://reactome.org/PathwayBrowser/#/R-CFA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Canis familiaris 1013 R-CFA-9009526 https://reactome.org/PathwayBrowser/#/R-CFA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 1013 R-CFA-9009533 https://reactome.org/PathwayBrowser/#/R-CFA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Canis familiaris 1013 R-CFA-9009536 https://reactome.org/PathwayBrowser/#/R-CFA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Canis familiaris 1013 R-CFA-9009541 https://reactome.org/PathwayBrowser/#/R-CFA-9009541 ESR1 binds to TFF1 gene promoter IEA Canis familiaris 1013 R-CFA-9023860 https://reactome.org/PathwayBrowser/#/R-CFA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Canis familiaris 1013 R-CFA-9023861 https://reactome.org/PathwayBrowser/#/R-CFA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 1013 R-CFA-9023884 https://reactome.org/PathwayBrowser/#/R-CFA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Canis familiaris 1013 R-DDI-5696822 https://reactome.org/PathwayBrowser/#/R-DDI-5696822 AKR1B15 reduces EST17b to E1 IEA Dictyostelium discoideum 1013 R-DDI-804969 https://reactome.org/PathwayBrowser/#/R-DDI-804969 HSD17B1 hydrogenates E1 to EST17b IEA Dictyostelium discoideum 1013 R-DDI-9023860 https://reactome.org/PathwayBrowser/#/R-DDI-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Dictyostelium discoideum 1013 R-DME-176521 https://reactome.org/PathwayBrowser/#/R-DME-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Drosophila melanogaster 1013 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 1013 R-DME-5693390 https://reactome.org/PathwayBrowser/#/R-DME-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Drosophila melanogaster 1013 R-DME-5696822 https://reactome.org/PathwayBrowser/#/R-DME-5696822 AKR1B15 reduces EST17b to E1 IEA Drosophila melanogaster 1013 R-DME-8862137 https://reactome.org/PathwayBrowser/#/R-DME-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Drosophila melanogaster 1013 R-DME-9008258 https://reactome.org/PathwayBrowser/#/R-DME-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Drosophila melanogaster 1013 R-DME-9008270 https://reactome.org/PathwayBrowser/#/R-DME-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Drosophila melanogaster 1013 R-DME-9008285 https://reactome.org/PathwayBrowser/#/R-DME-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Drosophila melanogaster 1013 R-DME-9009526 https://reactome.org/PathwayBrowser/#/R-DME-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 1013 R-DME-9009533 https://reactome.org/PathwayBrowser/#/R-DME-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Drosophila melanogaster 1013 R-DME-9009536 https://reactome.org/PathwayBrowser/#/R-DME-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Drosophila melanogaster 1013 R-DME-9009541 https://reactome.org/PathwayBrowser/#/R-DME-9009541 ESR1 binds to TFF1 gene promoter IEA Drosophila melanogaster 1013 R-DME-9023860 https://reactome.org/PathwayBrowser/#/R-DME-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Drosophila melanogaster 1013 R-DME-9023861 https://reactome.org/PathwayBrowser/#/R-DME-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 1013 R-DME-9023884 https://reactome.org/PathwayBrowser/#/R-DME-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Drosophila melanogaster 1013 R-DRE-176521 https://reactome.org/PathwayBrowser/#/R-DRE-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Danio rerio 1013 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 1013 R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 1013 R-DRE-5696822 https://reactome.org/PathwayBrowser/#/R-DRE-5696822 AKR1B15 reduces EST17b to E1 IEA Danio rerio 1013 R-DRE-6810594 https://reactome.org/PathwayBrowser/#/R-DRE-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Danio rerio 1013 R-DRE-9009526 https://reactome.org/PathwayBrowser/#/R-DRE-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Danio rerio 1013 R-DRE-9009533 https://reactome.org/PathwayBrowser/#/R-DRE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Danio rerio 1013 R-DRE-9009541 https://reactome.org/PathwayBrowser/#/R-DRE-9009541 ESR1 binds to TFF1 gene promoter IEA Danio rerio 1013 R-DRE-9023860 https://reactome.org/PathwayBrowser/#/R-DRE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Danio rerio 1013 R-GGA-176521 https://reactome.org/PathwayBrowser/#/R-GGA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Gallus gallus 1013 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 1013 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 1013 R-GGA-5693390 https://reactome.org/PathwayBrowser/#/R-GGA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Gallus gallus 1013 R-GGA-5696822 https://reactome.org/PathwayBrowser/#/R-GGA-5696822 AKR1B15 reduces EST17b to E1 IEA Gallus gallus 1013 R-GGA-8862137 https://reactome.org/PathwayBrowser/#/R-GGA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Gallus gallus 1013 R-GGA-9008258 https://reactome.org/PathwayBrowser/#/R-GGA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Gallus gallus 1013 R-GGA-9008270 https://reactome.org/PathwayBrowser/#/R-GGA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Gallus gallus 1013 R-GGA-9008285 https://reactome.org/PathwayBrowser/#/R-GGA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Gallus gallus 1013 R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus 1013 R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus 1013 R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus 1013 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus 1013 R-GGA-9023884 https://reactome.org/PathwayBrowser/#/R-GGA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Gallus gallus 1013 R-HSA-176521 https://reactome.org/PathwayBrowser/#/R-HSA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP TAS Homo sapiens 1013 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 1013 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 1013 R-HSA-5605147 https://reactome.org/PathwayBrowser/#/R-HSA-5605147 Defective CYP1B1 does not 4-hydroxylate EST17b TAS Homo sapiens 1013 R-HSA-5693390 https://reactome.org/PathwayBrowser/#/R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 TAS Homo sapiens 1013 R-HSA-5696822 https://reactome.org/PathwayBrowser/#/R-HSA-5696822 AKR1B15 reduces EST17b to E1 TAS Homo sapiens 1013 R-HSA-6810594 https://reactome.org/PathwayBrowser/#/R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 1013 R-HSA-804969 https://reactome.org/PathwayBrowser/#/R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b TAS Homo sapiens 1013 R-HSA-8862137 https://reactome.org/PathwayBrowser/#/R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 1013 R-HSA-9008258 https://reactome.org/PathwayBrowser/#/R-HSA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene TAS Homo sapiens 1013 R-HSA-9008267 https://reactome.org/PathwayBrowser/#/R-HSA-9008267 ESR1 binds to TGFA gene promoter TAS Homo sapiens 1013 R-HSA-9008270 https://reactome.org/PathwayBrowser/#/R-HSA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene TAS Homo sapiens 1013 R-HSA-9008271 https://reactome.org/PathwayBrowser/#/R-HSA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter TAS Homo sapiens 1013 R-HSA-9008285 https://reactome.org/PathwayBrowser/#/R-HSA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 TAS Homo sapiens 1013 R-HSA-9008315 https://reactome.org/PathwayBrowser/#/R-HSA-9008315 TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen TAS Homo sapiens 1013 R-HSA-9009526 https://reactome.org/PathwayBrowser/#/R-HSA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 1013 R-HSA-9009533 https://reactome.org/PathwayBrowser/#/R-HSA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter TAS Homo sapiens 1013 R-HSA-9009536 https://reactome.org/PathwayBrowser/#/R-HSA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter TAS Homo sapiens 1013 R-HSA-9009541 https://reactome.org/PathwayBrowser/#/R-HSA-9009541 ESR1 binds to TFF1 gene promoter TAS Homo sapiens 1013 R-HSA-9023859 https://reactome.org/PathwayBrowser/#/R-HSA-9023859 Estrogen-responsive TFF1 gene expression TAS Homo sapiens 1013 R-HSA-9023860 https://reactome.org/PathwayBrowser/#/R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene TAS Homo sapiens 1013 R-HSA-9023861 https://reactome.org/PathwayBrowser/#/R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 1013 R-HSA-9023884 https://reactome.org/PathwayBrowser/#/R-HSA-9023884 NCOA1 recruits EP300 to TGFA promoter TAS Homo sapiens 1013 R-MMU-176521 https://reactome.org/PathwayBrowser/#/R-MMU-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Mus musculus 1013 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 1013 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 1013 R-MMU-5693390 https://reactome.org/PathwayBrowser/#/R-MMU-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Mus musculus 1013 R-MMU-5696822 https://reactome.org/PathwayBrowser/#/R-MMU-5696822 AKR1B15 reduces EST17b to E1 IEA Mus musculus 1013 R-MMU-6810594 https://reactome.org/PathwayBrowser/#/R-MMU-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 1013 R-MMU-804969 https://reactome.org/PathwayBrowser/#/R-MMU-804969 HSD17B1 hydrogenates E1 to EST17b IEA Mus musculus 1013 R-MMU-8862137 https://reactome.org/PathwayBrowser/#/R-MMU-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 1013 R-MMU-9008258 https://reactome.org/PathwayBrowser/#/R-MMU-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Mus musculus 1013 R-MMU-9008270 https://reactome.org/PathwayBrowser/#/R-MMU-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Mus musculus 1013 R-MMU-9008271 https://reactome.org/PathwayBrowser/#/R-MMU-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Mus musculus 1013 R-MMU-9008285 https://reactome.org/PathwayBrowser/#/R-MMU-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Mus musculus 1013 R-MMU-9009526 https://reactome.org/PathwayBrowser/#/R-MMU-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 1013 R-MMU-9009533 https://reactome.org/PathwayBrowser/#/R-MMU-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Mus musculus 1013 R-MMU-9009536 https://reactome.org/PathwayBrowser/#/R-MMU-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Mus musculus 1013 R-MMU-9009541 https://reactome.org/PathwayBrowser/#/R-MMU-9009541 ESR1 binds to TFF1 gene promoter IEA Mus musculus 1013 R-MMU-9023860 https://reactome.org/PathwayBrowser/#/R-MMU-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Mus musculus 1013 R-MMU-9023861 https://reactome.org/PathwayBrowser/#/R-MMU-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 1013 R-MMU-9023884 https://reactome.org/PathwayBrowser/#/R-MMU-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Mus musculus 1013 R-RNO-176521 https://reactome.org/PathwayBrowser/#/R-RNO-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Rattus norvegicus 1013 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 1013 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 1013 R-RNO-5693390 https://reactome.org/PathwayBrowser/#/R-RNO-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Rattus norvegicus 1013 R-RNO-5696822 https://reactome.org/PathwayBrowser/#/R-RNO-5696822 AKR1B15 reduces EST17b to E1 IEA Rattus norvegicus 1013 R-RNO-6810594 https://reactome.org/PathwayBrowser/#/R-RNO-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 1013 R-RNO-804969 https://reactome.org/PathwayBrowser/#/R-RNO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Rattus norvegicus 1013 R-RNO-8862137 https://reactome.org/PathwayBrowser/#/R-RNO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 1013 R-RNO-9008258 https://reactome.org/PathwayBrowser/#/R-RNO-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Rattus norvegicus 1013 R-RNO-9008270 https://reactome.org/PathwayBrowser/#/R-RNO-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Rattus norvegicus 1013 R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus 1013 R-RNO-9008285 https://reactome.org/PathwayBrowser/#/R-RNO-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Rattus norvegicus 1013 R-RNO-9009526 https://reactome.org/PathwayBrowser/#/R-RNO-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 1013 R-RNO-9009533 https://reactome.org/PathwayBrowser/#/R-RNO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Rattus norvegicus 1013 R-RNO-9009536 https://reactome.org/PathwayBrowser/#/R-RNO-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Rattus norvegicus 1013 R-RNO-9009541 https://reactome.org/PathwayBrowser/#/R-RNO-9009541 ESR1 binds to TFF1 gene promoter IEA Rattus norvegicus 1013 R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus 1013 R-RNO-9023861 https://reactome.org/PathwayBrowser/#/R-RNO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 1013 R-RNO-9023884 https://reactome.org/PathwayBrowser/#/R-RNO-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Rattus norvegicus 1013 R-SCE-5693390 https://reactome.org/PathwayBrowser/#/R-SCE-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Saccharomyces cerevisiae 1013 R-SCE-5696822 https://reactome.org/PathwayBrowser/#/R-SCE-5696822 AKR1B15 reduces EST17b to E1 IEA Saccharomyces cerevisiae 1013 R-SCE-9009533 https://reactome.org/PathwayBrowser/#/R-SCE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Saccharomyces cerevisiae 1013 R-SCE-9023860 https://reactome.org/PathwayBrowser/#/R-SCE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Saccharomyces cerevisiae 1013 R-SCE-9023861 https://reactome.org/PathwayBrowser/#/R-SCE-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Saccharomyces cerevisiae 1013 R-SPO-5696822 https://reactome.org/PathwayBrowser/#/R-SPO-5696822 AKR1B15 reduces EST17b to E1 IEA Schizosaccharomyces pombe 1013 R-SPO-804969 https://reactome.org/PathwayBrowser/#/R-SPO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Schizosaccharomyces pombe 1013 R-SPO-8862137 https://reactome.org/PathwayBrowser/#/R-SPO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Schizosaccharomyces pombe 1013 R-SPO-9009533 https://reactome.org/PathwayBrowser/#/R-SPO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Schizosaccharomyces pombe 1013 R-SPO-9023860 https://reactome.org/PathwayBrowser/#/R-SPO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Schizosaccharomyces pombe 1013 R-SPO-9023861 https://reactome.org/PathwayBrowser/#/R-SPO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Schizosaccharomyces pombe 1013 R-SSC-176521 https://reactome.org/PathwayBrowser/#/R-SSC-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Sus scrofa 1013 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 1013 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 1013 R-SSC-5693390 https://reactome.org/PathwayBrowser/#/R-SSC-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Sus scrofa 1013 R-SSC-804969 https://reactome.org/PathwayBrowser/#/R-SSC-804969 HSD17B1 hydrogenates E1 to EST17b IEA Sus scrofa 1013 R-SSC-8862137 https://reactome.org/PathwayBrowser/#/R-SSC-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Sus scrofa 1013 R-SSC-9008258 https://reactome.org/PathwayBrowser/#/R-SSC-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Sus scrofa 1013 R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa 1013 R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa 1013 R-SSC-9008285 https://reactome.org/PathwayBrowser/#/R-SSC-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Sus scrofa 1013 R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 1013 R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa 1013 R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa 1013 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa 1013 R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 1013 R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa 1013 R-XTR-176521 https://reactome.org/PathwayBrowser/#/R-XTR-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP IEA Xenopus tropicalis 1013 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 1013 R-XTR-5693390 https://reactome.org/PathwayBrowser/#/R-XTR-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Xenopus tropicalis 1013 R-XTR-5696822 https://reactome.org/PathwayBrowser/#/R-XTR-5696822 AKR1B15 reduces EST17b to E1 IEA Xenopus tropicalis 1013 R-XTR-6810594 https://reactome.org/PathwayBrowser/#/R-XTR-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 1013 R-XTR-804969 https://reactome.org/PathwayBrowser/#/R-XTR-804969 HSD17B1 hydrogenates E1 to EST17b IEA Xenopus tropicalis 1013 R-XTR-8862137 https://reactome.org/PathwayBrowser/#/R-XTR-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 1013 R-XTR-9008258 https://reactome.org/PathwayBrowser/#/R-XTR-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Xenopus tropicalis 1013 R-XTR-9008285 https://reactome.org/PathwayBrowser/#/R-XTR-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Xenopus tropicalis 1013 R-XTR-9023860 https://reactome.org/PathwayBrowser/#/R-XTR-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Xenopus tropicalis 1015 R-BTA-9716913 https://reactome.org/PathwayBrowser/#/R-BTA-9716913 ESR1 binds ESR1 antagonists IEA Bos taurus 1015 R-DME-9716913 https://reactome.org/PathwayBrowser/#/R-DME-9716913 ESR1 binds ESR1 antagonists IEA Drosophila melanogaster 1015 R-DRE-9716913 https://reactome.org/PathwayBrowser/#/R-DRE-9716913 ESR1 binds ESR1 antagonists IEA Danio rerio 1015 R-GGA-9716913 https://reactome.org/PathwayBrowser/#/R-GGA-9716913 ESR1 binds ESR1 antagonists IEA Gallus gallus 1015 R-HSA-9716913 https://reactome.org/PathwayBrowser/#/R-HSA-9716913 ESR1 binds ESR1 antagonists TAS Homo sapiens 1015 R-MMU-9716913 https://reactome.org/PathwayBrowser/#/R-MMU-9716913 ESR1 binds ESR1 antagonists IEA Mus musculus 1015 R-RNO-9716913 https://reactome.org/PathwayBrowser/#/R-RNO-9716913 ESR1 binds ESR1 antagonists IEA Rattus norvegicus 1015 R-SSC-9716913 https://reactome.org/PathwayBrowser/#/R-SSC-9716913 ESR1 binds ESR1 antagonists IEA Sus scrofa 1015 R-XTR-9716913 https://reactome.org/PathwayBrowser/#/R-XTR-9716913 ESR1 binds ESR1 antagonists IEA Xenopus tropicalis 10159 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 10159 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 10159 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 10159 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 10159 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 10159 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 10159 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 10159 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 10159 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 10159 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 10159 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 10159 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 10159 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 10159 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 10159 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 1016 R-BTA-174916 https://reactome.org/PathwayBrowser/#/R-BTA-174916 Formation of N-glucuronides IEA Bos taurus 1016 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 1016 R-BTA-9716913 https://reactome.org/PathwayBrowser/#/R-BTA-9716913 ESR1 binds ESR1 antagonists IEA Bos taurus 1016 R-BTA-9716947 https://reactome.org/PathwayBrowser/#/R-BTA-9716947 ESR1 binds ESR1 agonists IEA Bos taurus 1016 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 1016 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 1016 R-DDI-174916 https://reactome.org/PathwayBrowser/#/R-DDI-174916 Formation of N-glucuronides IEA Dictyostelium discoideum 1016 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 1016 R-DME-9716913 https://reactome.org/PathwayBrowser/#/R-DME-9716913 ESR1 binds ESR1 antagonists IEA Drosophila melanogaster 1016 R-DME-9716947 https://reactome.org/PathwayBrowser/#/R-DME-9716947 ESR1 binds ESR1 agonists IEA Drosophila melanogaster 1016 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 1016 R-DRE-9716913 https://reactome.org/PathwayBrowser/#/R-DRE-9716913 ESR1 binds ESR1 antagonists IEA Danio rerio 1016 R-DRE-9716947 https://reactome.org/PathwayBrowser/#/R-DRE-9716947 ESR1 binds ESR1 agonists IEA Danio rerio 1016 R-GGA-174916 https://reactome.org/PathwayBrowser/#/R-GGA-174916 Formation of N-glucuronides IEA Gallus gallus 1016 R-GGA-9716913 https://reactome.org/PathwayBrowser/#/R-GGA-9716913 ESR1 binds ESR1 antagonists IEA Gallus gallus 1016 R-GGA-9716947 https://reactome.org/PathwayBrowser/#/R-GGA-9716947 ESR1 binds ESR1 agonists IEA Gallus gallus 1016 R-HSA-174916 https://reactome.org/PathwayBrowser/#/R-HSA-174916 Formation of N-glucuronides TAS Homo sapiens 1016 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 1016 R-HSA-9716913 https://reactome.org/PathwayBrowser/#/R-HSA-9716913 ESR1 binds ESR1 antagonists TAS Homo sapiens 1016 R-HSA-9716947 https://reactome.org/PathwayBrowser/#/R-HSA-9716947 ESR1 binds ESR1 agonists TAS Homo sapiens 1016 R-MMU-174916 https://reactome.org/PathwayBrowser/#/R-MMU-174916 Formation of N-glucuronides IEA Mus musculus 1016 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 1016 R-MMU-9716913 https://reactome.org/PathwayBrowser/#/R-MMU-9716913 ESR1 binds ESR1 antagonists IEA Mus musculus 1016 R-MMU-9716947 https://reactome.org/PathwayBrowser/#/R-MMU-9716947 ESR1 binds ESR1 agonists IEA Mus musculus 1016 R-RNO-174916 https://reactome.org/PathwayBrowser/#/R-RNO-174916 Formation of N-glucuronides IEA Rattus norvegicus 1016 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 1016 R-RNO-9716913 https://reactome.org/PathwayBrowser/#/R-RNO-9716913 ESR1 binds ESR1 antagonists IEA Rattus norvegicus 1016 R-RNO-9716947 https://reactome.org/PathwayBrowser/#/R-RNO-9716947 ESR1 binds ESR1 agonists IEA Rattus norvegicus 1016 R-SSC-174916 https://reactome.org/PathwayBrowser/#/R-SSC-174916 Formation of N-glucuronides IEA Sus scrofa 1016 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 1016 R-SSC-9716913 https://reactome.org/PathwayBrowser/#/R-SSC-9716913 ESR1 binds ESR1 antagonists IEA Sus scrofa 1016 R-SSC-9716947 https://reactome.org/PathwayBrowser/#/R-SSC-9716947 ESR1 binds ESR1 agonists IEA Sus scrofa 1016 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 1016 R-XTR-9716913 https://reactome.org/PathwayBrowser/#/R-XTR-9716913 ESR1 binds ESR1 antagonists IEA Xenopus tropicalis 1016 R-XTR-9716947 https://reactome.org/PathwayBrowser/#/R-XTR-9716947 ESR1 binds ESR1 agonists IEA Xenopus tropicalis 10160 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 10160 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 10160 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 10160 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 10160 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 10160 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 10160 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 10160 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 10160 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 10160 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 10168 R-BTA-9691621 https://reactome.org/PathwayBrowser/#/R-BTA-9691621 C5 binds C5 inhibitors IEA Bos taurus 10168 R-CFA-9691621 https://reactome.org/PathwayBrowser/#/R-CFA-9691621 C5 binds C5 inhibitors IEA Canis familiaris 10168 R-GGA-9691621 https://reactome.org/PathwayBrowser/#/R-GGA-9691621 C5 binds C5 inhibitors IEA Gallus gallus 10168 R-HSA-9691621 https://reactome.org/PathwayBrowser/#/R-HSA-9691621 C5 binds C5 inhibitors TAS Homo sapiens 10168 R-MMU-9691621 https://reactome.org/PathwayBrowser/#/R-MMU-9691621 C5 binds C5 inhibitors IEA Mus musculus 10168 R-RNO-9691621 https://reactome.org/PathwayBrowser/#/R-RNO-9691621 C5 binds C5 inhibitors IEA Rattus norvegicus 10168 R-SSC-9691621 https://reactome.org/PathwayBrowser/#/R-SSC-9691621 C5 binds C5 inhibitors IEA Sus scrofa 10172 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 10176 R-BTA-9702849 https://reactome.org/PathwayBrowser/#/R-BTA-9702849 CALCR binds gepants IEA Bos taurus 10176 R-CEL-9702849 https://reactome.org/PathwayBrowser/#/R-CEL-9702849 CALCR binds gepants IEA Caenorhabditis elegans 10176 R-CFA-9702849 https://reactome.org/PathwayBrowser/#/R-CFA-9702849 CALCR binds gepants IEA Canis familiaris 10176 R-DME-9702849 https://reactome.org/PathwayBrowser/#/R-DME-9702849 CALCR binds gepants IEA Drosophila melanogaster 10176 R-GGA-9702849 https://reactome.org/PathwayBrowser/#/R-GGA-9702849 CALCR binds gepants IEA Gallus gallus 10176 R-HSA-9702849 https://reactome.org/PathwayBrowser/#/R-HSA-9702849 CALCR binds gepants TAS Homo sapiens 10176 R-MMU-9702849 https://reactome.org/PathwayBrowser/#/R-MMU-9702849 CALCR binds gepants IEA Mus musculus 10176 R-RNO-9702849 https://reactome.org/PathwayBrowser/#/R-RNO-9702849 CALCR binds gepants IEA Rattus norvegicus 10176 R-SSC-9702849 https://reactome.org/PathwayBrowser/#/R-SSC-9702849 CALCR binds gepants IEA Sus scrofa 10176 R-XTR-9702849 https://reactome.org/PathwayBrowser/#/R-XTR-9702849 CALCR binds gepants IEA Xenopus tropicalis 10199 R-HSA-9700266 https://reactome.org/PathwayBrowser/#/R-HSA-9700266 CFTR F508del binds CFTR correctors TAS Homo sapiens 102 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 102 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 102 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 102 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 102 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 102 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 102 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 102 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 102 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 102 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 102 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 102 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 102 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 102 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 102 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 102 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 102 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 102 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 102 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 102 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 102 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 102 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 102 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 102 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 102 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 102 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 102 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 102 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 102 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 102 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 102 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 102 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 102 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 102 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 102 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 102 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 102 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 102 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 102 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 102 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 102 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 102 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 102 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 102 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 102 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 102 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 102 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 102 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 102 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 102 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 102 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 102 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 10209 R-BTA-9678766 https://reactome.org/PathwayBrowser/#/R-BTA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Bos taurus 10209 R-CFA-9678766 https://reactome.org/PathwayBrowser/#/R-CFA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Canis familiaris 10209 R-DRE-9678766 https://reactome.org/PathwayBrowser/#/R-DRE-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Danio rerio 10209 R-GGA-9678766 https://reactome.org/PathwayBrowser/#/R-GGA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Gallus gallus 10209 R-HSA-9678766 https://reactome.org/PathwayBrowser/#/R-HSA-9678766 CYP3A4 binds CYP3A4 inhibitors TAS Homo sapiens 10209 R-MMU-9678766 https://reactome.org/PathwayBrowser/#/R-MMU-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Mus musculus 10209 R-RNO-9678766 https://reactome.org/PathwayBrowser/#/R-RNO-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Rattus norvegicus 10209 R-SSC-9678766 https://reactome.org/PathwayBrowser/#/R-SSC-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Sus scrofa 10209 R-XTR-9678766 https://reactome.org/PathwayBrowser/#/R-XTR-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Xenopus tropicalis 10219 R-BTA-9695917 https://reactome.org/PathwayBrowser/#/R-BTA-9695917 SPHK2 binds SPHK2 inhibitors IEA Bos taurus 10219 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 10219 R-CEL-9695917 https://reactome.org/PathwayBrowser/#/R-CEL-9695917 SPHK2 binds SPHK2 inhibitors IEA Caenorhabditis elegans 10219 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 10219 R-CFA-9695917 https://reactome.org/PathwayBrowser/#/R-CFA-9695917 SPHK2 binds SPHK2 inhibitors IEA Canis familiaris 10219 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 10219 R-DDI-9695917 https://reactome.org/PathwayBrowser/#/R-DDI-9695917 SPHK2 binds SPHK2 inhibitors IEA Dictyostelium discoideum 10219 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 10219 R-DME-9695917 https://reactome.org/PathwayBrowser/#/R-DME-9695917 SPHK2 binds SPHK2 inhibitors IEA Drosophila melanogaster 10219 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 10219 R-HSA-9695917 https://reactome.org/PathwayBrowser/#/R-HSA-9695917 SPHK2 binds SPHK2 inhibitors TAS Homo sapiens 10219 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 10219 R-MMU-9695917 https://reactome.org/PathwayBrowser/#/R-MMU-9695917 SPHK2 binds SPHK2 inhibitors IEA Mus musculus 10219 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 10219 R-RNO-9695917 https://reactome.org/PathwayBrowser/#/R-RNO-9695917 SPHK2 binds SPHK2 inhibitors IEA Rattus norvegicus 10219 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 10219 R-SCE-9695917 https://reactome.org/PathwayBrowser/#/R-SCE-9695917 SPHK2 binds SPHK2 inhibitors IEA Saccharomyces cerevisiae 10219 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 10219 R-SPO-9695917 https://reactome.org/PathwayBrowser/#/R-SPO-9695917 SPHK2 binds SPHK2 inhibitors IEA Schizosaccharomyces pombe 10219 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 10219 R-SSC-9695917 https://reactome.org/PathwayBrowser/#/R-SSC-9695917 SPHK2 binds SPHK2 inhibitors IEA Sus scrofa 10219 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 10219 R-XTR-9695917 https://reactome.org/PathwayBrowser/#/R-XTR-9695917 SPHK2 binds SPHK2 inhibitors IEA Xenopus tropicalis 10219 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 1024 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 1024 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 1024 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 1024 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 1024 R-HSA-2025882 https://reactome.org/PathwayBrowser/#/R-HSA-2025882 Calcineurin dephosphorylates NFATC1,2,3 IEA Homo sapiens 1024 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 1024 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 1024 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 1024 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 1024 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 1024 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 103 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 103 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 103 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 103 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 103 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 103 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 103 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 103 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 103 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 103 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 103 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 103 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 103 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 103 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 103 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 103 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 103 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 103 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 103 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 103 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 10313 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 10313 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 10313 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 10313 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 10313 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 10313 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 10313 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 10313 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 10313 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 10313 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 10313 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 10313 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 10313 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 10313 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 10313 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 10313 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 10313 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 10313 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 10313 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 10313 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 10313 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 10313 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 10313 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 10313 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 10313 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 10313 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 10313 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 10313 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 10313 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 10342 R-BTA-9714580 https://reactome.org/PathwayBrowser/#/R-BTA-9714580 SLC6A3 binds DRIs IEA Bos taurus 10342 R-CEL-9714580 https://reactome.org/PathwayBrowser/#/R-CEL-9714580 SLC6A3 binds DRIs IEA Caenorhabditis elegans 10342 R-CFA-9714580 https://reactome.org/PathwayBrowser/#/R-CFA-9714580 SLC6A3 binds DRIs IEA Canis familiaris 10342 R-DME-9714580 https://reactome.org/PathwayBrowser/#/R-DME-9714580 SLC6A3 binds DRIs IEA Drosophila melanogaster 10342 R-DRE-9714580 https://reactome.org/PathwayBrowser/#/R-DRE-9714580 SLC6A3 binds DRIs IEA Danio rerio 10342 R-HSA-9714580 https://reactome.org/PathwayBrowser/#/R-HSA-9714580 SLC6A3 binds DRIs TAS Homo sapiens 10342 R-MMU-9714580 https://reactome.org/PathwayBrowser/#/R-MMU-9714580 SLC6A3 binds DRIs IEA Mus musculus 10342 R-PFA-9714580 https://reactome.org/PathwayBrowser/#/R-PFA-9714580 SLC6A3 binds DRIs IEA Plasmodium falciparum 10342 R-RNO-9714580 https://reactome.org/PathwayBrowser/#/R-RNO-9714580 SLC6A3 binds DRIs IEA Rattus norvegicus 10342 R-SSC-9714580 https://reactome.org/PathwayBrowser/#/R-SSC-9714580 SLC6A3 binds DRIs IEA Sus scrofa 10342 R-XTR-9714580 https://reactome.org/PathwayBrowser/#/R-XTR-9714580 SLC6A3 binds DRIs IEA Xenopus tropicalis 10346 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 10346 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 10346 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 10346 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 10346 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 10346 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 10346 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 10346 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 10346 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 10346 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 10346 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 10346 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 10346 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 10346 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 10346 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 10346 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 10346 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 10346 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 10346 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 10346 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 10368 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 10368 R-BTA-389083 https://reactome.org/PathwayBrowser/#/R-BTA-389083 Autophosphorylation of PDGF alpha receptors IEA Bos taurus 10368 R-BTA-9669893 https://reactome.org/PathwayBrowser/#/R-BTA-9669893 KIT binds type I TKIs IEA Bos taurus 10368 R-BTA-9674093 https://reactome.org/PathwayBrowser/#/R-BTA-9674093 PDGFRs bind type I TKI IEA Bos taurus 10368 R-CEL-389083 https://reactome.org/PathwayBrowser/#/R-CEL-389083 Autophosphorylation of PDGF alpha receptors IEA Caenorhabditis elegans 10368 R-CEL-9674093 https://reactome.org/PathwayBrowser/#/R-CEL-9674093 PDGFRs bind type I TKI IEA Caenorhabditis elegans 10368 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 10368 R-CFA-389083 https://reactome.org/PathwayBrowser/#/R-CFA-389083 Autophosphorylation of PDGF alpha receptors IEA Canis familiaris 10368 R-CFA-9669893 https://reactome.org/PathwayBrowser/#/R-CFA-9669893 KIT binds type I TKIs IEA Canis familiaris 10368 R-CFA-9674093 https://reactome.org/PathwayBrowser/#/R-CFA-9674093 PDGFRs bind type I TKI IEA Canis familiaris 10368 R-DME-389083 https://reactome.org/PathwayBrowser/#/R-DME-389083 Autophosphorylation of PDGF alpha receptors IEA Drosophila melanogaster 10368 R-DME-9674093 https://reactome.org/PathwayBrowser/#/R-DME-9674093 PDGFRs bind type I TKI IEA Drosophila melanogaster 10368 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 10368 R-DRE-389083 https://reactome.org/PathwayBrowser/#/R-DRE-389083 Autophosphorylation of PDGF alpha receptors IEA Danio rerio 10368 R-DRE-9669893 https://reactome.org/PathwayBrowser/#/R-DRE-9669893 KIT binds type I TKIs IEA Danio rerio 10368 R-DRE-9674093 https://reactome.org/PathwayBrowser/#/R-DRE-9674093 PDGFRs bind type I TKI IEA Danio rerio 10368 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 10368 R-GGA-389083 https://reactome.org/PathwayBrowser/#/R-GGA-389083 Autophosphorylation of PDGF alpha receptors IEA Gallus gallus 10368 R-GGA-9669893 https://reactome.org/PathwayBrowser/#/R-GGA-9669893 KIT binds type I TKIs IEA Gallus gallus 10368 R-GGA-9674093 https://reactome.org/PathwayBrowser/#/R-GGA-9674093 PDGFRs bind type I TKI IEA Gallus gallus 10368 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 10368 R-HSA-389083 https://reactome.org/PathwayBrowser/#/R-HSA-389083 Autophosphorylation of PDGF alpha receptors TAS Homo sapiens 10368 R-HSA-9669893 https://reactome.org/PathwayBrowser/#/R-HSA-9669893 KIT binds type I TKIs TAS Homo sapiens 10368 R-HSA-9669898 https://reactome.org/PathwayBrowser/#/R-HSA-9669898 KIT mutants bind type I TKIs TAS Homo sapiens 10368 R-HSA-9674093 https://reactome.org/PathwayBrowser/#/R-HSA-9674093 PDGFRs bind type I TKI TAS Homo sapiens 10368 R-HSA-9674427 https://reactome.org/PathwayBrowser/#/R-HSA-9674427 PDGFR mutants bind type I TKIs TAS Homo sapiens 10368 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 10368 R-MMU-389083 https://reactome.org/PathwayBrowser/#/R-MMU-389083 Autophosphorylation of PDGF alpha receptors IEA Mus musculus 10368 R-MMU-9669893 https://reactome.org/PathwayBrowser/#/R-MMU-9669893 KIT binds type I TKIs IEA Mus musculus 10368 R-MMU-9674093 https://reactome.org/PathwayBrowser/#/R-MMU-9674093 PDGFRs bind type I TKI IEA Mus musculus 10368 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 10368 R-RNO-389083 https://reactome.org/PathwayBrowser/#/R-RNO-389083 Autophosphorylation of PDGF alpha receptors IEA Rattus norvegicus 10368 R-RNO-9669893 https://reactome.org/PathwayBrowser/#/R-RNO-9669893 KIT binds type I TKIs IEA Rattus norvegicus 10368 R-RNO-9674093 https://reactome.org/PathwayBrowser/#/R-RNO-9674093 PDGFRs bind type I TKI IEA Rattus norvegicus 10368 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 10368 R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa 10368 R-SSC-9669893 https://reactome.org/PathwayBrowser/#/R-SSC-9669893 KIT binds type I TKIs IEA Sus scrofa 10368 R-SSC-9674093 https://reactome.org/PathwayBrowser/#/R-SSC-9674093 PDGFRs bind type I TKI IEA Sus scrofa 10368 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 10368 R-XTR-9669893 https://reactome.org/PathwayBrowser/#/R-XTR-9669893 KIT binds type I TKIs IEA Xenopus tropicalis 10369 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 10369 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 10369 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 10369 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 10369 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 10369 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 10369 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 10369 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 10369 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 10369 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 10369 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 10387 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 10387 R-BTA-9653108 https://reactome.org/PathwayBrowser/#/R-BTA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Bos taurus 10387 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 10387 R-CEL-9653108 https://reactome.org/PathwayBrowser/#/R-CEL-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Caenorhabditis elegans 10387 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 10387 R-CFA-9653108 https://reactome.org/PathwayBrowser/#/R-CFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Canis familiaris 10387 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 10387 R-DME-9653108 https://reactome.org/PathwayBrowser/#/R-DME-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Drosophila melanogaster 10387 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 10387 R-GGA-9653108 https://reactome.org/PathwayBrowser/#/R-GGA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Gallus gallus 10387 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 10387 R-HSA-9653108 https://reactome.org/PathwayBrowser/#/R-HSA-9653108 Raf dimer inhibitors bind RAF heterodimers TAS Homo sapiens 10387 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 10387 R-MMU-9653108 https://reactome.org/PathwayBrowser/#/R-MMU-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Mus musculus 10387 R-PFA-9653108 https://reactome.org/PathwayBrowser/#/R-PFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Plasmodium falciparum 10387 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 10387 R-RNO-9653108 https://reactome.org/PathwayBrowser/#/R-RNO-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Rattus norvegicus 10387 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 10387 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa 10404 R-BTA-9691621 https://reactome.org/PathwayBrowser/#/R-BTA-9691621 C5 binds C5 inhibitors IEA Bos taurus 10404 R-CFA-9691621 https://reactome.org/PathwayBrowser/#/R-CFA-9691621 C5 binds C5 inhibitors IEA Canis familiaris 10404 R-GGA-9691621 https://reactome.org/PathwayBrowser/#/R-GGA-9691621 C5 binds C5 inhibitors IEA Gallus gallus 10404 R-HSA-9691621 https://reactome.org/PathwayBrowser/#/R-HSA-9691621 C5 binds C5 inhibitors TAS Homo sapiens 10404 R-MMU-9691621 https://reactome.org/PathwayBrowser/#/R-MMU-9691621 C5 binds C5 inhibitors IEA Mus musculus 10404 R-RNO-9691621 https://reactome.org/PathwayBrowser/#/R-RNO-9691621 C5 binds C5 inhibitors IEA Rattus norvegicus 10404 R-SSC-9691621 https://reactome.org/PathwayBrowser/#/R-SSC-9691621 C5 binds C5 inhibitors IEA Sus scrofa 10423 R-BTA-419049 https://reactome.org/PathwayBrowser/#/R-BTA-419049 ROCK activation by RHO IEA Bos taurus 10423 R-BTA-9680443 https://reactome.org/PathwayBrowser/#/R-BTA-9680443 ROCK1,2 bind ROCKi IEA Bos taurus 10423 R-CEL-419049 https://reactome.org/PathwayBrowser/#/R-CEL-419049 ROCK activation by RHO IEA Caenorhabditis elegans 10423 R-CEL-9680443 https://reactome.org/PathwayBrowser/#/R-CEL-9680443 ROCK1,2 bind ROCKi IEA Caenorhabditis elegans 10423 R-CFA-419049 https://reactome.org/PathwayBrowser/#/R-CFA-419049 ROCK activation by RHO IEA Canis familiaris 10423 R-CFA-9680443 https://reactome.org/PathwayBrowser/#/R-CFA-9680443 ROCK1,2 bind ROCKi IEA Canis familiaris 10423 R-DME-419049 https://reactome.org/PathwayBrowser/#/R-DME-419049 ROCK activation by RHO IEA Drosophila melanogaster 10423 R-DME-9680443 https://reactome.org/PathwayBrowser/#/R-DME-9680443 ROCK1,2 bind ROCKi IEA Drosophila melanogaster 10423 R-DRE-419049 https://reactome.org/PathwayBrowser/#/R-DRE-419049 ROCK activation by RHO IEA Danio rerio 10423 R-DRE-9680443 https://reactome.org/PathwayBrowser/#/R-DRE-9680443 ROCK1,2 bind ROCKi IEA Danio rerio 10423 R-GGA-419049 https://reactome.org/PathwayBrowser/#/R-GGA-419049 ROCK activation by RHO IEA Gallus gallus 10423 R-GGA-9680443 https://reactome.org/PathwayBrowser/#/R-GGA-9680443 ROCK1,2 bind ROCKi IEA Gallus gallus 10423 R-HSA-419049 https://reactome.org/PathwayBrowser/#/R-HSA-419049 ROCK activation by RHO TAS Homo sapiens 10423 R-HSA-9680443 https://reactome.org/PathwayBrowser/#/R-HSA-9680443 ROCK1,2 bind ROCKi TAS Homo sapiens 10423 R-MMU-419049 https://reactome.org/PathwayBrowser/#/R-MMU-419049 ROCK activation by RHO IEA Mus musculus 10423 R-MMU-9680443 https://reactome.org/PathwayBrowser/#/R-MMU-9680443 ROCK1,2 bind ROCKi IEA Mus musculus 10423 R-RNO-419049 https://reactome.org/PathwayBrowser/#/R-RNO-419049 ROCK activation by RHO IEA Rattus norvegicus 10423 R-RNO-9680443 https://reactome.org/PathwayBrowser/#/R-RNO-9680443 ROCK1,2 bind ROCKi IEA Rattus norvegicus 10423 R-SSC-419049 https://reactome.org/PathwayBrowser/#/R-SSC-419049 ROCK activation by RHO IEA Sus scrofa 10423 R-SSC-9680443 https://reactome.org/PathwayBrowser/#/R-SSC-9680443 ROCK1,2 bind ROCKi IEA Sus scrofa 10423 R-XTR-419049 https://reactome.org/PathwayBrowser/#/R-XTR-419049 ROCK activation by RHO IEA Xenopus tropicalis 10423 R-XTR-9680443 https://reactome.org/PathwayBrowser/#/R-XTR-9680443 ROCK1,2 bind ROCKi IEA Xenopus tropicalis 10426 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 10426 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 10426 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 10426 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 10426 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 10426 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 10426 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 10426 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 10426 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 10426 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 10426 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 10426 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 10426 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 10426 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 10426 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 10426 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 10426 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 10426 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 10426 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 10426 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 10426 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 10426 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 10426 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 10426 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 10426 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 10426 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 10426 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 10426 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 10426 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 10439 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 10439 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 10439 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 10439 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 10439 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 10439 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 10439 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 10439 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 10439 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 10439 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 10439 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 10470 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 10470 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 10470 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 10470 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 10470 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 10470 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 10470 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 10470 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 10470 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 10470 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 10470 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 1049 R-BTA-2026996 https://reactome.org/PathwayBrowser/#/R-BTA-2026996 FABP1 transports fatty acids into the nucleus IEA Bos taurus 1049 R-BTA-2046085 https://reactome.org/PathwayBrowser/#/R-BTA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Bos taurus 1049 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 1049 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 1049 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 1049 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 1049 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 1049 R-CEL-2026996 https://reactome.org/PathwayBrowser/#/R-CEL-2026996 FABP1 transports fatty acids into the nucleus IEA Caenorhabditis elegans 1049 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 1049 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 1049 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 1049 R-CFA-2026996 https://reactome.org/PathwayBrowser/#/R-CFA-2026996 FABP1 transports fatty acids into the nucleus IEA Canis familiaris 1049 R-CFA-2046085 https://reactome.org/PathwayBrowser/#/R-CFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Canis familiaris 1049 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 1049 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 1049 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 1049 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 1049 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 1049 R-DDI-2046085 https://reactome.org/PathwayBrowser/#/R-DDI-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Dictyostelium discoideum 1049 R-DME-2026996 https://reactome.org/PathwayBrowser/#/R-DME-2026996 FABP1 transports fatty acids into the nucleus IEA Drosophila melanogaster 1049 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 1049 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 1049 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 1049 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 1049 R-DRE-2026996 https://reactome.org/PathwayBrowser/#/R-DRE-2026996 FABP1 transports fatty acids into the nucleus IEA Danio rerio 1049 R-DRE-2046085 https://reactome.org/PathwayBrowser/#/R-DRE-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Danio rerio 1049 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 1049 R-GGA-2026996 https://reactome.org/PathwayBrowser/#/R-GGA-2026996 FABP1 transports fatty acids into the nucleus IEA Gallus gallus 1049 R-GGA-2046085 https://reactome.org/PathwayBrowser/#/R-GGA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Gallus gallus 1049 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 1049 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 1049 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 1049 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 1049 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 1049 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 RORA and PPARA positively regulate and NR1D1 negatively regulates expression of NPAS2 IEA Homo sapiens 1049 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 1049 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 1049 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 1049 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 1049 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of Carnitine O-palmitoyltransferase 1 CPT1A IEA Homo sapiens 1049 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 1049 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 1049 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 1049 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 1049 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 1049 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 1049 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 1049 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 1049 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 1049 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 1049 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 1049 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 1049 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 1049 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 1049 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 1049 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 1049 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 1049 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 1049 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 1049 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 1049 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 1049 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 1049 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 1049 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 1049 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 1049 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 1049 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 1049 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 1049 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 1049 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 1049 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 1049 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 1049 R-HSA-2026996 https://reactome.org/PathwayBrowser/#/R-HSA-2026996 FABP1 transports fatty acids into the nucleus TAS Homo sapiens 1049 R-HSA-2046085 https://reactome.org/PathwayBrowser/#/R-HSA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA TAS Homo sapiens 1049 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 1049 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 1049 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 1049 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 1049 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 1049 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 1049 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 1049 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 1049 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 1049 R-MMU-2026996 https://reactome.org/PathwayBrowser/#/R-MMU-2026996 FABP1 transports fatty acids into the nucleus IEA Mus musculus 1049 R-MMU-2046085 https://reactome.org/PathwayBrowser/#/R-MMU-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Mus musculus 1049 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 1049 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 1049 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 1049 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 1049 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 1049 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 1049 R-PFA-2046085 https://reactome.org/PathwayBrowser/#/R-PFA-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Plasmodium falciparum 1049 R-RNO-2026996 https://reactome.org/PathwayBrowser/#/R-RNO-2026996 FABP1 transports fatty acids into the nucleus IEA Rattus norvegicus 1049 R-RNO-2046085 https://reactome.org/PathwayBrowser/#/R-RNO-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Rattus norvegicus 1049 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 1049 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 1049 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 1049 R-SSC-2046085 https://reactome.org/PathwayBrowser/#/R-SSC-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Sus scrofa 1049 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 1049 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 1049 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 1049 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 1049 R-XTR-2026996 https://reactome.org/PathwayBrowser/#/R-XTR-2026996 FABP1 transports fatty acids into the nucleus IEA Xenopus tropicalis 1049 R-XTR-2046085 https://reactome.org/PathwayBrowser/#/R-XTR-2046085 Activation of alpha-linolenic acid to alpha-linolenoyl-CoA IEA Xenopus tropicalis 1049 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 10507 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 10507 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 10507 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 10507 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 10507 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 10507 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 10507 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 10507 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 10507 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 10507 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 10507 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 10507 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 10507 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 10507 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 10507 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 10507 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 10507 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 10507 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 10512 R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 10512 R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 10512 R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 10512 R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 10512 R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 10512 R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 10512 R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 1052 R-BTA-2026996 https://reactome.org/PathwayBrowser/#/R-BTA-2026996 FABP1 transports fatty acids into the nucleus IEA Bos taurus 1052 R-BTA-2046098 https://reactome.org/PathwayBrowser/#/R-BTA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Bos taurus 1052 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 1052 R-BTA-400143 https://reactome.org/PathwayBrowser/#/R-BTA-400143 Fatty acid ligands activate PPARA IEA Bos taurus 1052 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 1052 R-CEL-2026996 https://reactome.org/PathwayBrowser/#/R-CEL-2026996 FABP1 transports fatty acids into the nucleus IEA Caenorhabditis elegans 1052 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 1052 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 1052 R-CFA-2026996 https://reactome.org/PathwayBrowser/#/R-CFA-2026996 FABP1 transports fatty acids into the nucleus IEA Canis familiaris 1052 R-CFA-2046098 https://reactome.org/PathwayBrowser/#/R-CFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Canis familiaris 1052 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 1052 R-CFA-400143 https://reactome.org/PathwayBrowser/#/R-CFA-400143 Fatty acid ligands activate PPARA IEA Canis familiaris 1052 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 1052 R-DDI-2046098 https://reactome.org/PathwayBrowser/#/R-DDI-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Dictyostelium discoideum 1052 R-DME-2026996 https://reactome.org/PathwayBrowser/#/R-DME-2026996 FABP1 transports fatty acids into the nucleus IEA Drosophila melanogaster 1052 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 1052 R-DME-400143 https://reactome.org/PathwayBrowser/#/R-DME-400143 Fatty acid ligands activate PPARA IEA Drosophila melanogaster 1052 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 1052 R-DRE-2026996 https://reactome.org/PathwayBrowser/#/R-DRE-2026996 FABP1 transports fatty acids into the nucleus IEA Danio rerio 1052 R-DRE-2046098 https://reactome.org/PathwayBrowser/#/R-DRE-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Danio rerio 1052 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 1052 R-DRE-400143 https://reactome.org/PathwayBrowser/#/R-DRE-400143 Fatty acid ligands activate PPARA IEA Danio rerio 1052 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 1052 R-GGA-2026996 https://reactome.org/PathwayBrowser/#/R-GGA-2026996 FABP1 transports fatty acids into the nucleus IEA Gallus gallus 1052 R-GGA-2046098 https://reactome.org/PathwayBrowser/#/R-GGA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Gallus gallus 1052 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 1052 R-GGA-400143 https://reactome.org/PathwayBrowser/#/R-GGA-400143 Fatty acid ligands activate PPARA IEA Gallus gallus 1052 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 1052 R-HSA-1368065 https://reactome.org/PathwayBrowser/#/R-HSA-1368065 RORA and PPARA positively regulate and NR1D1 negatively regulates expression of NPAS2 IEA Homo sapiens 1052 R-HSA-1592238 https://reactome.org/PathwayBrowser/#/R-HSA-1592238 Expression of ALAS1 TAS Homo sapiens 1052 R-HSA-1655826 https://reactome.org/PathwayBrowser/#/R-HSA-1655826 Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) TAS Homo sapiens 1052 R-HSA-1655848 https://reactome.org/PathwayBrowser/#/R-HSA-1655848 Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) TAS Homo sapiens 1052 R-HSA-1655850 https://reactome.org/PathwayBrowser/#/R-HSA-1655850 Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) TAS Homo sapiens 1052 R-HSA-1801587 https://reactome.org/PathwayBrowser/#/R-HSA-1801587 Expression of Carnitine O-palmitoyltransferase 1 CPT1A IEA Homo sapiens 1052 R-HSA-1989745 https://reactome.org/PathwayBrowser/#/R-HSA-1989745 Expression of ACADM TAS Homo sapiens 1052 R-HSA-1989746 https://reactome.org/PathwayBrowser/#/R-HSA-1989746 Expression of CYP7A1 TAS Homo sapiens 1052 R-HSA-1989747 https://reactome.org/PathwayBrowser/#/R-HSA-1989747 Expression of FHL2 TAS Homo sapiens 1052 R-HSA-1989748 https://reactome.org/PathwayBrowser/#/R-HSA-1989748 Expression of GRHL1 TAS Homo sapiens 1052 R-HSA-1989749 https://reactome.org/PathwayBrowser/#/R-HSA-1989749 Expression of ACOX1 TAS Homo sapiens 1052 R-HSA-1989750 https://reactome.org/PathwayBrowser/#/R-HSA-1989750 Expression of FATP1 (SLC27A1) TAS Homo sapiens 1052 R-HSA-1989751 https://reactome.org/PathwayBrowser/#/R-HSA-1989751 Expression of FABP1 TAS Homo sapiens 1052 R-HSA-1989752 https://reactome.org/PathwayBrowser/#/R-HSA-1989752 Expression of TXNRD1 TAS Homo sapiens 1052 R-HSA-1989753 https://reactome.org/PathwayBrowser/#/R-HSA-1989753 Expression of PEX11A TAS Homo sapiens 1052 R-HSA-1989754 https://reactome.org/PathwayBrowser/#/R-HSA-1989754 Expression of APOA1 TAS Homo sapiens 1052 R-HSA-1989755 https://reactome.org/PathwayBrowser/#/R-HSA-1989755 Expression of CYP4A11 TAS Homo sapiens 1052 R-HSA-1989756 https://reactome.org/PathwayBrowser/#/R-HSA-1989756 Expression of ME1 TAS Homo sapiens 1052 R-HSA-1989757 https://reactome.org/PathwayBrowser/#/R-HSA-1989757 Expression of FADS1 TAS Homo sapiens 1052 R-HSA-1989758 https://reactome.org/PathwayBrowser/#/R-HSA-1989758 Expression of UGT1A9 TAS Homo sapiens 1052 R-HSA-1989759 https://reactome.org/PathwayBrowser/#/R-HSA-1989759 Expression of G0S2 TAS Homo sapiens 1052 R-HSA-1989760 https://reactome.org/PathwayBrowser/#/R-HSA-1989760 Expression of HMGCS2 TAS Homo sapiens 1052 R-HSA-1989761 https://reactome.org/PathwayBrowser/#/R-HSA-1989761 Expression of APOA5 TAS Homo sapiens 1052 R-HSA-1989762 https://reactome.org/PathwayBrowser/#/R-HSA-1989762 Expression of ABCB4 TAS Homo sapiens 1052 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 1052 R-HSA-1989765 https://reactome.org/PathwayBrowser/#/R-HSA-1989765 Expression of ABCA1 TAS Homo sapiens 1052 R-HSA-1989767 https://reactome.org/PathwayBrowser/#/R-HSA-1989767 Expression of TRIB3 TAS Homo sapiens 1052 R-HSA-1989768 https://reactome.org/PathwayBrowser/#/R-HSA-1989768 Expression of TIAM2 TAS Homo sapiens 1052 R-HSA-1989770 https://reactome.org/PathwayBrowser/#/R-HSA-1989770 Expression of PLIN2 TAS Homo sapiens 1052 R-HSA-1989771 https://reactome.org/PathwayBrowser/#/R-HSA-1989771 Expression of TNFRSF21 TAS Homo sapiens 1052 R-HSA-1989772 https://reactome.org/PathwayBrowser/#/R-HSA-1989772 Expression of GLIPR1 TAS Homo sapiens 1052 R-HSA-1989773 https://reactome.org/PathwayBrowser/#/R-HSA-1989773 Expression of CPT2 TAS Homo sapiens 1052 R-HSA-1989774 https://reactome.org/PathwayBrowser/#/R-HSA-1989774 Expression of AGT TAS Homo sapiens 1052 R-HSA-1989775 https://reactome.org/PathwayBrowser/#/R-HSA-1989775 Expression of SULT2A1 TAS Homo sapiens 1052 R-HSA-1989776 https://reactome.org/PathwayBrowser/#/R-HSA-1989776 Expression of APOA2 TAS Homo sapiens 1052 R-HSA-1989777 https://reactome.org/PathwayBrowser/#/R-HSA-1989777 Expression of RGL1 TAS Homo sapiens 1052 R-HSA-1989778 https://reactome.org/PathwayBrowser/#/R-HSA-1989778 Expression of ACSL1 TAS Homo sapiens 1052 R-HSA-1989779 https://reactome.org/PathwayBrowser/#/R-HSA-1989779 Expression of ANKRD1 TAS Homo sapiens 1052 R-HSA-2026996 https://reactome.org/PathwayBrowser/#/R-HSA-2026996 FABP1 transports fatty acids into the nucleus TAS Homo sapiens 1052 R-HSA-2046098 https://reactome.org/PathwayBrowser/#/R-HSA-2046098 Activation of linoleic acid to linoleoyl-CoA TAS Homo sapiens 1052 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 1052 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 1052 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 1052 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 1052 R-HSA-400143 https://reactome.org/PathwayBrowser/#/R-HSA-400143 Fatty acid ligands activate PPARA TAS Homo sapiens 1052 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 1052 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 1052 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 1052 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 1052 R-HSA-879724 https://reactome.org/PathwayBrowser/#/R-HSA-879724 Expression of PPARA IEA Homo sapiens 1052 R-MMU-2026996 https://reactome.org/PathwayBrowser/#/R-MMU-2026996 FABP1 transports fatty acids into the nucleus IEA Mus musculus 1052 R-MMU-2046098 https://reactome.org/PathwayBrowser/#/R-MMU-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Mus musculus 1052 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 1052 R-MMU-400143 https://reactome.org/PathwayBrowser/#/R-MMU-400143 Fatty acid ligands activate PPARA IEA Mus musculus 1052 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 1052 R-PFA-2046098 https://reactome.org/PathwayBrowser/#/R-PFA-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Plasmodium falciparum 1052 R-RNO-2026996 https://reactome.org/PathwayBrowser/#/R-RNO-2026996 FABP1 transports fatty acids into the nucleus IEA Rattus norvegicus 1052 R-RNO-2046098 https://reactome.org/PathwayBrowser/#/R-RNO-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Rattus norvegicus 1052 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 1052 R-RNO-400143 https://reactome.org/PathwayBrowser/#/R-RNO-400143 Fatty acid ligands activate PPARA IEA Rattus norvegicus 1052 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 1052 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 1052 R-SSC-2046098 https://reactome.org/PathwayBrowser/#/R-SSC-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Sus scrofa 1052 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 1052 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 1052 R-XTR-2026996 https://reactome.org/PathwayBrowser/#/R-XTR-2026996 FABP1 transports fatty acids into the nucleus IEA Xenopus tropicalis 1052 R-XTR-2046098 https://reactome.org/PathwayBrowser/#/R-XTR-2046098 Activation of linoleic acid to linoleoyl-CoA IEA Xenopus tropicalis 1052 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 1052 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 10522 R-HSA-9681169 https://reactome.org/PathwayBrowser/#/R-HSA-9681169 CRBN binds IMiDs TAS Homo sapiens 10525 R-BTA-9716258 https://reactome.org/PathwayBrowser/#/R-BTA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Bos taurus 10525 R-CFA-9716258 https://reactome.org/PathwayBrowser/#/R-CFA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Canis familiaris 10525 R-GGA-9716258 https://reactome.org/PathwayBrowser/#/R-GGA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Gallus gallus 10525 R-HSA-9716258 https://reactome.org/PathwayBrowser/#/R-HSA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD TAS Homo sapiens 10525 R-MMU-9716258 https://reactome.org/PathwayBrowser/#/R-MMU-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Mus musculus 10525 R-RNO-9716258 https://reactome.org/PathwayBrowser/#/R-RNO-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Rattus norvegicus 10525 R-SSC-9716258 https://reactome.org/PathwayBrowser/#/R-SSC-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Sus scrofa 10552 R-HSA-9700266 https://reactome.org/PathwayBrowser/#/R-HSA-9700266 CFTR F508del binds CFTR correctors TAS Homo sapiens 10553 R-HSA-9700266 https://reactome.org/PathwayBrowser/#/R-HSA-9700266 CFTR F508del binds CFTR correctors TAS Homo sapiens 1056 R-BTA-9732527 https://reactome.org/PathwayBrowser/#/R-BTA-9732527 FFAR1 binds rosiglitazone IEA Bos taurus 1056 R-BTA-9732629 https://reactome.org/PathwayBrowser/#/R-BTA-9732629 PPARG binds PPARG agonists IEA Bos taurus 1056 R-CEL-9732629 https://reactome.org/PathwayBrowser/#/R-CEL-9732629 PPARG binds PPARG agonists IEA Caenorhabditis elegans 1056 R-CFA-9732527 https://reactome.org/PathwayBrowser/#/R-CFA-9732527 FFAR1 binds rosiglitazone IEA Canis familiaris 1056 R-CFA-9732629 https://reactome.org/PathwayBrowser/#/R-CFA-9732629 PPARG binds PPARG agonists IEA Canis familiaris 1056 R-DME-9732629 https://reactome.org/PathwayBrowser/#/R-DME-9732629 PPARG binds PPARG agonists IEA Drosophila melanogaster 1056 R-GGA-9732629 https://reactome.org/PathwayBrowser/#/R-GGA-9732629 PPARG binds PPARG agonists IEA Gallus gallus 1056 R-HSA-9732527 https://reactome.org/PathwayBrowser/#/R-HSA-9732527 FFAR1 binds rosiglitazone TAS Homo sapiens 1056 R-HSA-9732629 https://reactome.org/PathwayBrowser/#/R-HSA-9732629 PPARG binds PPARG agonists TAS Homo sapiens 1056 R-MMU-9732527 https://reactome.org/PathwayBrowser/#/R-MMU-9732527 FFAR1 binds rosiglitazone IEA Mus musculus 1056 R-MMU-9732629 https://reactome.org/PathwayBrowser/#/R-MMU-9732629 PPARG binds PPARG agonists IEA Mus musculus 1056 R-RNO-9732527 https://reactome.org/PathwayBrowser/#/R-RNO-9732527 FFAR1 binds rosiglitazone IEA Rattus norvegicus 1056 R-RNO-9732629 https://reactome.org/PathwayBrowser/#/R-RNO-9732629 PPARG binds PPARG agonists IEA Rattus norvegicus 1056 R-SSC-9732629 https://reactome.org/PathwayBrowser/#/R-SSC-9732629 PPARG binds PPARG agonists IEA Sus scrofa 1058 R-BTA-162857 https://reactome.org/PathwayBrowser/#/R-BTA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Bos taurus 1058 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 1058 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Bos taurus 1058 R-BTA-444047 https://reactome.org/PathwayBrowser/#/R-BTA-444047 Receptor FFAR3 binds carboxylates IEA Bos taurus 1058 R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 1058 R-BTA-5691507 https://reactome.org/PathwayBrowser/#/R-BTA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Bos taurus 1058 R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 1058 R-BTA-71735 https://reactome.org/PathwayBrowser/#/R-BTA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Bos taurus 1058 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 1058 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 1058 R-BTA-8869206 https://reactome.org/PathwayBrowser/#/R-BTA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Bos taurus 1058 R-BTA-9701565 https://reactome.org/PathwayBrowser/#/R-BTA-9701565 HDACs deacetylate p-STAT3 dimers IEA Bos taurus 1058 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 1058 R-CEL-162857 https://reactome.org/PathwayBrowser/#/R-CEL-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Caenorhabditis elegans 1058 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 1058 R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 1058 R-CEL-71735 https://reactome.org/PathwayBrowser/#/R-CEL-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Caenorhabditis elegans 1058 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 1058 R-CEL-8869206 https://reactome.org/PathwayBrowser/#/R-CEL-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Caenorhabditis elegans 1058 R-CEL-9701565 https://reactome.org/PathwayBrowser/#/R-CEL-9701565 HDACs deacetylate p-STAT3 dimers IEA Caenorhabditis elegans 1058 R-CFA-162857 https://reactome.org/PathwayBrowser/#/R-CFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Canis familiaris 1058 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 1058 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Canis familiaris 1058 R-CFA-444047 https://reactome.org/PathwayBrowser/#/R-CFA-444047 Receptor FFAR3 binds carboxylates IEA Canis familiaris 1058 R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 1058 R-CFA-5691507 https://reactome.org/PathwayBrowser/#/R-CFA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Canis familiaris 1058 R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 1058 R-CFA-71735 https://reactome.org/PathwayBrowser/#/R-CFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Canis familiaris 1058 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 1058 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 1058 R-CFA-8869206 https://reactome.org/PathwayBrowser/#/R-CFA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Canis familiaris 1058 R-CFA-9701565 https://reactome.org/PathwayBrowser/#/R-CFA-9701565 HDACs deacetylate p-STAT3 dimers IEA Canis familiaris 1058 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 1058 R-DDI-162857 https://reactome.org/PathwayBrowser/#/R-DDI-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Dictyostelium discoideum 1058 R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 1058 R-DDI-71735 https://reactome.org/PathwayBrowser/#/R-DDI-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Dictyostelium discoideum 1058 R-DDI-9701565 https://reactome.org/PathwayBrowser/#/R-DDI-9701565 HDACs deacetylate p-STAT3 dimers IEA Dictyostelium discoideum 1058 R-DME-162857 https://reactome.org/PathwayBrowser/#/R-DME-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Drosophila melanogaster 1058 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 1058 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 1058 R-DME-71735 https://reactome.org/PathwayBrowser/#/R-DME-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Drosophila melanogaster 1058 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 1058 R-DME-8952069 https://reactome.org/PathwayBrowser/#/R-DME-8952069 HDAC4 deacetylates RUNX3 IEA Drosophila melanogaster 1058 R-DME-9701565 https://reactome.org/PathwayBrowser/#/R-DME-9701565 HDACs deacetylate p-STAT3 dimers IEA Drosophila melanogaster 1058 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 1058 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Danio rerio 1058 R-DRE-444047 https://reactome.org/PathwayBrowser/#/R-DRE-444047 Receptor FFAR3 binds carboxylates IEA Danio rerio 1058 R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 1058 R-DRE-5691507 https://reactome.org/PathwayBrowser/#/R-DRE-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Danio rerio 1058 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 1058 R-GGA-162857 https://reactome.org/PathwayBrowser/#/R-GGA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Gallus gallus 1058 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 1058 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Gallus gallus 1058 R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 1058 R-GGA-5691507 https://reactome.org/PathwayBrowser/#/R-GGA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Gallus gallus 1058 R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 1058 R-GGA-71735 https://reactome.org/PathwayBrowser/#/R-GGA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Gallus gallus 1058 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 1058 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 1058 R-GGA-8869206 https://reactome.org/PathwayBrowser/#/R-GGA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Gallus gallus 1058 R-GGA-9701565 https://reactome.org/PathwayBrowser/#/R-GGA-9701565 HDACs deacetylate p-STAT3 dimers IEA Gallus gallus 1058 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 1058 R-HSA-162857 https://reactome.org/PathwayBrowser/#/R-HSA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate TAS Homo sapiens 1058 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 1058 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol TAS Homo sapiens 1058 R-HSA-433672 https://reactome.org/PathwayBrowser/#/R-HSA-433672 NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 IEA Homo sapiens 1058 R-HSA-444047 https://reactome.org/PathwayBrowser/#/R-HSA-444047 Receptor FFAR3 binds carboxylates TAS Homo sapiens 1058 R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 1058 R-HSA-5691507 https://reactome.org/PathwayBrowser/#/R-HSA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate TAS Homo sapiens 1058 R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 1058 R-HSA-71735 https://reactome.org/PathwayBrowser/#/R-HSA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] TAS Homo sapiens 1058 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 1058 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 1058 R-HSA-8869206 https://reactome.org/PathwayBrowser/#/R-HSA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate TAS Homo sapiens 1058 R-HSA-8952069 https://reactome.org/PathwayBrowser/#/R-HSA-8952069 HDAC4 deacetylates RUNX3 TAS Homo sapiens 1058 R-HSA-9701565 https://reactome.org/PathwayBrowser/#/R-HSA-9701565 HDACs deacetylate p-STAT3 dimers TAS Homo sapiens 1058 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 1058 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 1058 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 1058 R-HSA-9737111 https://reactome.org/PathwayBrowser/#/R-HSA-9737111 Protonated weak acid translocates across the plasma membrane IEA Homo sapiens 1058 R-MMU-162857 https://reactome.org/PathwayBrowser/#/R-MMU-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Mus musculus 1058 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 1058 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Mus musculus 1058 R-MMU-444047 https://reactome.org/PathwayBrowser/#/R-MMU-444047 Receptor FFAR3 binds carboxylates IEA Mus musculus 1058 R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 1058 R-MMU-5691507 https://reactome.org/PathwayBrowser/#/R-MMU-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Mus musculus 1058 R-MMU-573376 https://reactome.org/PathwayBrowser/#/R-MMU-573376 NoRC:intergenic spacer:Hdac:Dnmt complex deacetylates histone H4 and dimethylates lysine-9 of histone H3 in main promoter of the rRNA gene TAS Mus musculus 1058 R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 1058 R-MMU-71735 https://reactome.org/PathwayBrowser/#/R-MMU-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Mus musculus 1058 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 1058 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 1058 R-MMU-8869206 https://reactome.org/PathwayBrowser/#/R-MMU-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Mus musculus 1058 R-MMU-9701565 https://reactome.org/PathwayBrowser/#/R-MMU-9701565 HDACs deacetylate p-STAT3 dimers IEA Mus musculus 1058 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 1058 R-MMU-9750040 https://reactome.org/PathwayBrowser/#/R-MMU-9750040 Protonated weak acid translocates across the plasma membrane TAS Mus musculus 1058 R-MTU-879327 https://reactome.org/PathwayBrowser/#/R-MTU-879327 acetylglucosamine-inositol is deacetylated by Mca TAS Mycobacterium tuberculosis 1058 R-MTU-936642 https://reactome.org/PathwayBrowser/#/R-MTU-936642 deacetylation of O-acetylserine and sulfhydrylation using CysK1 TAS Mycobacterium tuberculosis 1058 R-MTU-936745 https://reactome.org/PathwayBrowser/#/R-MTU-936745 deacetylation of O-acetylserine and sulfhydrylation using CysK2 TAS Mycobacterium tuberculosis 1058 R-PFA-162857 https://reactome.org/PathwayBrowser/#/R-PFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Plasmodium falciparum 1058 R-PFA-71735 https://reactome.org/PathwayBrowser/#/R-PFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Plasmodium falciparum 1058 R-RNO-162857 https://reactome.org/PathwayBrowser/#/R-RNO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Rattus norvegicus 1058 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 1058 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Rattus norvegicus 1058 R-RNO-444047 https://reactome.org/PathwayBrowser/#/R-RNO-444047 Receptor FFAR3 binds carboxylates IEA Rattus norvegicus 1058 R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 1058 R-RNO-5691507 https://reactome.org/PathwayBrowser/#/R-RNO-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Rattus norvegicus 1058 R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 1058 R-RNO-71735 https://reactome.org/PathwayBrowser/#/R-RNO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Rattus norvegicus 1058 R-RNO-8869206 https://reactome.org/PathwayBrowser/#/R-RNO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Rattus norvegicus 1058 R-RNO-9701565 https://reactome.org/PathwayBrowser/#/R-RNO-9701565 HDACs deacetylate p-STAT3 dimers IEA Rattus norvegicus 1058 R-RNO-9749957 https://reactome.org/PathwayBrowser/#/R-RNO-9749957 Protonated weak acid translocates across the plasma membrane TAS Rattus norvegicus 1058 R-SCE-162857 https://reactome.org/PathwayBrowser/#/R-SCE-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Saccharomyces cerevisiae 1058 R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 1058 R-SCE-71735 https://reactome.org/PathwayBrowser/#/R-SCE-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Saccharomyces cerevisiae 1058 R-SPO-162857 https://reactome.org/PathwayBrowser/#/R-SPO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Schizosaccharomyces pombe 1058 R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 1058 R-SPO-71735 https://reactome.org/PathwayBrowser/#/R-SPO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Schizosaccharomyces pombe 1058 R-SPO-8869206 https://reactome.org/PathwayBrowser/#/R-SPO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Schizosaccharomyces pombe 1058 R-SSC-162857 https://reactome.org/PathwayBrowser/#/R-SSC-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Sus scrofa 1058 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 1058 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Sus scrofa 1058 R-SSC-444047 https://reactome.org/PathwayBrowser/#/R-SSC-444047 Receptor FFAR3 binds carboxylates IEA Sus scrofa 1058 R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 1058 R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Sus scrofa 1058 R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 1058 R-SSC-71735 https://reactome.org/PathwayBrowser/#/R-SSC-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Sus scrofa 1058 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 1058 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 1058 R-SSC-8869206 https://reactome.org/PathwayBrowser/#/R-SSC-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Sus scrofa 1058 R-SSC-9701565 https://reactome.org/PathwayBrowser/#/R-SSC-9701565 HDACs deacetylate p-STAT3 dimers IEA Sus scrofa 1058 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 1058 R-XTR-162857 https://reactome.org/PathwayBrowser/#/R-XTR-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Xenopus tropicalis 1058 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 1058 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 1058 R-XTR-5691507 https://reactome.org/PathwayBrowser/#/R-XTR-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Xenopus tropicalis 1058 R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 1058 R-XTR-71735 https://reactome.org/PathwayBrowser/#/R-XTR-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Xenopus tropicalis 1058 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 1058 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 1058 R-XTR-8869206 https://reactome.org/PathwayBrowser/#/R-XTR-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Xenopus tropicalis 1058 R-XTR-9701565 https://reactome.org/PathwayBrowser/#/R-XTR-9701565 HDACs deacetylate p-STAT3 dimers IEA Xenopus tropicalis 10583 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 10583 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 10583 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 10583 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 10583 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 10583 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 10583 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 10583 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 10583 R-HSA-9731708 https://reactome.org/PathwayBrowser/#/R-HSA-9731708 nsp10:nsp14 binds to ExoN inhibitors TAS Homo sapiens 10608 R-BTA-9701211 https://reactome.org/PathwayBrowser/#/R-BTA-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Bos taurus 10608 R-CFA-9701211 https://reactome.org/PathwayBrowser/#/R-CFA-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Canis familiaris 10608 R-DDI-9701211 https://reactome.org/PathwayBrowser/#/R-DDI-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Dictyostelium discoideum 10608 R-DME-9701211 https://reactome.org/PathwayBrowser/#/R-DME-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Drosophila melanogaster 10608 R-DRE-9701211 https://reactome.org/PathwayBrowser/#/R-DRE-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Danio rerio 10608 R-GGA-9701211 https://reactome.org/PathwayBrowser/#/R-GGA-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Gallus gallus 10608 R-HSA-9701211 https://reactome.org/PathwayBrowser/#/R-HSA-9701211 TRPA1 tetramer binds TRPA1 antagonists TAS Homo sapiens 10608 R-MMU-9701211 https://reactome.org/PathwayBrowser/#/R-MMU-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Mus musculus 10608 R-RNO-9701211 https://reactome.org/PathwayBrowser/#/R-RNO-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Rattus norvegicus 10608 R-SCE-9701211 https://reactome.org/PathwayBrowser/#/R-SCE-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Saccharomyces cerevisiae 10608 R-SSC-9701211 https://reactome.org/PathwayBrowser/#/R-SSC-9701211 TRPA1 tetramer binds TRPA1 antagonists IEA Sus scrofa 1062 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 1062 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Bos taurus 1062 R-BTA-444047 https://reactome.org/PathwayBrowser/#/R-BTA-444047 Receptor FFAR3 binds carboxylates IEA Bos taurus 1062 R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 1062 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 1062 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 1062 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 1062 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 1062 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 1062 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 1062 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Canis familiaris 1062 R-CFA-444047 https://reactome.org/PathwayBrowser/#/R-CFA-444047 Receptor FFAR3 binds carboxylates IEA Canis familiaris 1062 R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 1062 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 1062 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 1062 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 1062 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 1062 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 1062 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 1062 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Danio rerio 1062 R-DRE-444047 https://reactome.org/PathwayBrowser/#/R-DRE-444047 Receptor FFAR3 binds carboxylates IEA Danio rerio 1062 R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 1062 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 1062 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 1062 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Gallus gallus 1062 R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 1062 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 1062 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 1062 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 1062 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 1062 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol TAS Homo sapiens 1062 R-HSA-444047 https://reactome.org/PathwayBrowser/#/R-HSA-444047 Receptor FFAR3 binds carboxylates TAS Homo sapiens 1062 R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 1062 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 1062 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 1062 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 1062 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 1062 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 1062 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 1062 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Mus musculus 1062 R-MMU-444047 https://reactome.org/PathwayBrowser/#/R-MMU-444047 Receptor FFAR3 binds carboxylates IEA Mus musculus 1062 R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 1062 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 1062 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 1062 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 1062 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 1062 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Rattus norvegicus 1062 R-RNO-444047 https://reactome.org/PathwayBrowser/#/R-RNO-444047 Receptor FFAR3 binds carboxylates IEA Rattus norvegicus 1062 R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 1062 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 1062 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Sus scrofa 1062 R-SSC-444047 https://reactome.org/PathwayBrowser/#/R-SSC-444047 Receptor FFAR3 binds carboxylates IEA Sus scrofa 1062 R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 1062 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 1062 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 1062 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 1062 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 1062 R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 1062 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 1062 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 10641 R-BTA-9695917 https://reactome.org/PathwayBrowser/#/R-BTA-9695917 SPHK2 binds SPHK2 inhibitors IEA Bos taurus 10641 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 10641 R-CEL-9695917 https://reactome.org/PathwayBrowser/#/R-CEL-9695917 SPHK2 binds SPHK2 inhibitors IEA Caenorhabditis elegans 10641 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 10641 R-CFA-9695917 https://reactome.org/PathwayBrowser/#/R-CFA-9695917 SPHK2 binds SPHK2 inhibitors IEA Canis familiaris 10641 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 10641 R-DDI-9695917 https://reactome.org/PathwayBrowser/#/R-DDI-9695917 SPHK2 binds SPHK2 inhibitors IEA Dictyostelium discoideum 10641 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 10641 R-DME-9695917 https://reactome.org/PathwayBrowser/#/R-DME-9695917 SPHK2 binds SPHK2 inhibitors IEA Drosophila melanogaster 10641 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 10641 R-HSA-9695917 https://reactome.org/PathwayBrowser/#/R-HSA-9695917 SPHK2 binds SPHK2 inhibitors TAS Homo sapiens 10641 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 10641 R-MMU-9695917 https://reactome.org/PathwayBrowser/#/R-MMU-9695917 SPHK2 binds SPHK2 inhibitors IEA Mus musculus 10641 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 10641 R-RNO-9695917 https://reactome.org/PathwayBrowser/#/R-RNO-9695917 SPHK2 binds SPHK2 inhibitors IEA Rattus norvegicus 10641 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 10641 R-SCE-9695917 https://reactome.org/PathwayBrowser/#/R-SCE-9695917 SPHK2 binds SPHK2 inhibitors IEA Saccharomyces cerevisiae 10641 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 10641 R-SPO-9695917 https://reactome.org/PathwayBrowser/#/R-SPO-9695917 SPHK2 binds SPHK2 inhibitors IEA Schizosaccharomyces pombe 10641 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 10641 R-SSC-9695917 https://reactome.org/PathwayBrowser/#/R-SSC-9695917 SPHK2 binds SPHK2 inhibitors IEA Sus scrofa 10641 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 10641 R-XTR-9695917 https://reactome.org/PathwayBrowser/#/R-XTR-9695917 SPHK2 binds SPHK2 inhibitors IEA Xenopus tropicalis 10641 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 10694 R-BTA-9702354 https://reactome.org/PathwayBrowser/#/R-BTA-9702354 CALCA(83-119) binds CALCA antibodies IEA Bos taurus 10694 R-CFA-9702354 https://reactome.org/PathwayBrowser/#/R-CFA-9702354 CALCA(83-119) binds CALCA antibodies IEA Canis familiaris 10694 R-DRE-9702354 https://reactome.org/PathwayBrowser/#/R-DRE-9702354 CALCA(83-119) binds CALCA antibodies IEA Danio rerio 10694 R-GGA-9702354 https://reactome.org/PathwayBrowser/#/R-GGA-9702354 CALCA(83-119) binds CALCA antibodies IEA Gallus gallus 10694 R-HSA-9702354 https://reactome.org/PathwayBrowser/#/R-HSA-9702354 CALCA(83-119) binds CALCA antibodies TAS Homo sapiens 10694 R-MMU-9702354 https://reactome.org/PathwayBrowser/#/R-MMU-9702354 CALCA(83-119) binds CALCA antibodies IEA Mus musculus 10694 R-RNO-9702354 https://reactome.org/PathwayBrowser/#/R-RNO-9702354 CALCA(83-119) binds CALCA antibodies IEA Rattus norvegicus 10694 R-SSC-9702354 https://reactome.org/PathwayBrowser/#/R-SSC-9702354 CALCA(83-119) binds CALCA antibodies IEA Sus scrofa 10694 R-XTR-9702354 https://reactome.org/PathwayBrowser/#/R-XTR-9702354 CALCA(83-119) binds CALCA antibodies IEA Xenopus tropicalis 10704 R-BTA-9702849 https://reactome.org/PathwayBrowser/#/R-BTA-9702849 CALCR binds gepants IEA Bos taurus 10704 R-CEL-9702849 https://reactome.org/PathwayBrowser/#/R-CEL-9702849 CALCR binds gepants IEA Caenorhabditis elegans 10704 R-CFA-9702849 https://reactome.org/PathwayBrowser/#/R-CFA-9702849 CALCR binds gepants IEA Canis familiaris 10704 R-DME-9702849 https://reactome.org/PathwayBrowser/#/R-DME-9702849 CALCR binds gepants IEA Drosophila melanogaster 10704 R-GGA-9702849 https://reactome.org/PathwayBrowser/#/R-GGA-9702849 CALCR binds gepants IEA Gallus gallus 10704 R-HSA-9702849 https://reactome.org/PathwayBrowser/#/R-HSA-9702849 CALCR binds gepants TAS Homo sapiens 10704 R-MMU-9702849 https://reactome.org/PathwayBrowser/#/R-MMU-9702849 CALCR binds gepants IEA Mus musculus 10704 R-RNO-9702849 https://reactome.org/PathwayBrowser/#/R-RNO-9702849 CALCR binds gepants IEA Rattus norvegicus 10704 R-SSC-9702849 https://reactome.org/PathwayBrowser/#/R-SSC-9702849 CALCR binds gepants IEA Sus scrofa 10704 R-XTR-9702849 https://reactome.org/PathwayBrowser/#/R-XTR-9702849 CALCR binds gepants IEA Xenopus tropicalis 10705 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 10705 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 10705 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 10705 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 10705 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 10705 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 10705 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 10705 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 10714 R-HSA-9685655 https://reactome.org/PathwayBrowser/#/R-HSA-9685655 CTSL bind CTSL inhibitors TAS Homo sapiens 10714 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 10714 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 10715 R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 10715 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 10715 R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 10715 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 10715 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 10715 R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 10715 R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 10715 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 10715 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 10715 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 10715 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 10715 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 10715 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 10715 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 10720 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 10720 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 10720 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 10720 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 10720 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 10720 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 10720 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 10720 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 10732 R-HSA-9681514 https://reactome.org/PathwayBrowser/#/R-HSA-9681514 TMPRSS2 binds TMPRSS2 inhibitors TAS Homo sapiens 10732 R-HSA-9686731 https://reactome.org/PathwayBrowser/#/R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 10732 R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 10733 R-HSA-9681514 https://reactome.org/PathwayBrowser/#/R-HSA-9681514 TMPRSS2 binds TMPRSS2 inhibitors TAS Homo sapiens 10733 R-HSA-9686731 https://reactome.org/PathwayBrowser/#/R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 10733 R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 10737 R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 10737 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 10737 R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 10737 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 10737 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 10737 R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 10737 R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 10737 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 10737 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 10737 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 10737 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 10737 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 10737 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 10737 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 10829 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 10882 R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 10894 R-HSA-9911462 https://reactome.org/PathwayBrowser/#/R-HSA-9911462 Aminoglycoside antibiotics bind Kpn 16S rRNA TAS Homo sapiens 10894 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 10894 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 10900 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 10902 R-HSA-9793564 https://reactome.org/PathwayBrowser/#/R-HSA-9793564 Cipro HCl dissolves TAS Homo sapiens 10902 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 10902 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 10902 R-HSA-9913142 https://reactome.org/PathwayBrowser/#/R-HSA-9913142 Fluoroquinolones bind gyrase TAS Homo sapiens 10902 R-HSA-9913373 https://reactome.org/PathwayBrowser/#/R-HSA-9913373 AAC(6′)-Ib acetylates ciprofloxacin TAS Homo sapiens 10902 R-HSA-9913437 https://reactome.org/PathwayBrowser/#/R-HSA-9913437 Pef exports fluoroquinolones TAS Homo sapiens 10902 R-HSA-9913672 https://reactome.org/PathwayBrowser/#/R-HSA-9913672 OqxA exports fluoroquinolones TAS Homo sapiens 10911 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 10911 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 10911 R-HSA-9913142 https://reactome.org/PathwayBrowser/#/R-HSA-9913142 Fluoroquinolones bind gyrase TAS Homo sapiens 10911 R-HSA-9913437 https://reactome.org/PathwayBrowser/#/R-HSA-9913437 Pef exports fluoroquinolones TAS Homo sapiens 10911 R-HSA-9913672 https://reactome.org/PathwayBrowser/#/R-HSA-9913672 OqxA exports fluoroquinolones TAS Homo sapiens 10923 R-HSA-9911462 https://reactome.org/PathwayBrowser/#/R-HSA-9911462 Aminoglycoside antibiotics bind Kpn 16S rRNA TAS Homo sapiens 10923 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 10923 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 10924 R-HSA-9685655 https://reactome.org/PathwayBrowser/#/R-HSA-9685655 CTSL bind CTSL inhibitors TAS Homo sapiens 10924 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 10924 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 10927 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 10927 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 10927 R-HSA-9911517 https://reactome.org/PathwayBrowser/#/R-HSA-9911517 MdfA transports tetracyclines from the cytosol to the periplasmic space TAS Homo sapiens 10927 R-HSA-9912784 https://reactome.org/PathwayBrowser/#/R-HSA-9912784 Tetracycline antibiotics bind to 16S rRNA TAS Homo sapiens 10927 R-HSA-9913106 https://reactome.org/PathwayBrowser/#/R-HSA-9913106 TetB exports tetracyclines TAS Homo sapiens 10927 R-HSA-9913128 https://reactome.org/PathwayBrowser/#/R-HSA-9913128 TetA exports tetracyclines TAS Homo sapiens 10928 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 10930 R-HSA-9911462 https://reactome.org/PathwayBrowser/#/R-HSA-9911462 Aminoglycoside antibiotics bind Kpn 16S rRNA TAS Homo sapiens 10930 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 10930 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 10935 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 10937 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 10948 R-HSA-164504 https://reactome.org/PathwayBrowser/#/R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) TAS Homo sapiens 10948 R-HSA-9697051 https://reactome.org/PathwayBrowser/#/R-HSA-9697051 RTC binds NRTIs TAS Homo sapiens 11090 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 11090 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 11090 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 11090 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 11090 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 11090 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 11090 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 11090 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 11134 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 11134 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 11134 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 11134 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 11134 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 11134 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 11134 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 11152 R-BTA-2161500 https://reactome.org/PathwayBrowser/#/R-BTA-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Bos taurus 11152 R-BTA-2162078 https://reactome.org/PathwayBrowser/#/R-BTA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Bos taurus 11152 R-CEL-2161500 https://reactome.org/PathwayBrowser/#/R-CEL-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Caenorhabditis elegans 11152 R-CEL-2162078 https://reactome.org/PathwayBrowser/#/R-CEL-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Caenorhabditis elegans 11152 R-CFA-2161500 https://reactome.org/PathwayBrowser/#/R-CFA-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Canis familiaris 11152 R-CFA-2162078 https://reactome.org/PathwayBrowser/#/R-CFA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Canis familiaris 11152 R-DDI-2162078 https://reactome.org/PathwayBrowser/#/R-DDI-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Dictyostelium discoideum 11152 R-DME-2161500 https://reactome.org/PathwayBrowser/#/R-DME-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Drosophila melanogaster 11152 R-DME-2162078 https://reactome.org/PathwayBrowser/#/R-DME-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Drosophila melanogaster 11152 R-DRE-2161500 https://reactome.org/PathwayBrowser/#/R-DRE-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Danio rerio 11152 R-DRE-2162078 https://reactome.org/PathwayBrowser/#/R-DRE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Danio rerio 11152 R-GGA-2161500 https://reactome.org/PathwayBrowser/#/R-GGA-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Gallus gallus 11152 R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus 11152 R-HSA-2161193 https://reactome.org/PathwayBrowser/#/R-HSA-2161193 abacavir + AMP => abacavir monophosphate + adenosine TAS Homo sapiens 11152 R-HSA-2161500 https://reactome.org/PathwayBrowser/#/R-HSA-2161500 abacavir [extracellular] => abacavir [cytosol] TAS Homo sapiens 11152 R-HSA-2161506 https://reactome.org/PathwayBrowser/#/R-HSA-2161506 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 11152 R-HSA-2161538 https://reactome.org/PathwayBrowser/#/R-HSA-2161538 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 11152 R-HSA-2162078 https://reactome.org/PathwayBrowser/#/R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ TAS Homo sapiens 11152 R-HSA-2162099 https://reactome.org/PathwayBrowser/#/R-HSA-2162099 abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP TAS Homo sapiens 11152 R-MMU-2161500 https://reactome.org/PathwayBrowser/#/R-MMU-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Mus musculus 11152 R-MMU-2161526 https://reactome.org/PathwayBrowser/#/R-MMU-2161526 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 11152 R-MMU-2161533 https://reactome.org/PathwayBrowser/#/R-MMU-2161533 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 11152 R-MMU-2162078 https://reactome.org/PathwayBrowser/#/R-MMU-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Mus musculus 11152 R-RNO-2161500 https://reactome.org/PathwayBrowser/#/R-RNO-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Rattus norvegicus 11152 R-RNO-2162078 https://reactome.org/PathwayBrowser/#/R-RNO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Rattus norvegicus 11152 R-SCE-2162078 https://reactome.org/PathwayBrowser/#/R-SCE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Saccharomyces cerevisiae 11152 R-SPO-2162078 https://reactome.org/PathwayBrowser/#/R-SPO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Schizosaccharomyces pombe 11152 R-SSC-2161500 https://reactome.org/PathwayBrowser/#/R-SSC-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Sus scrofa 11152 R-SSC-2162078 https://reactome.org/PathwayBrowser/#/R-SSC-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Sus scrofa 11152 R-XTR-2161500 https://reactome.org/PathwayBrowser/#/R-XTR-2161500 abacavir [extracellular] => abacavir [cytosol] IEA Xenopus tropicalis 11152 R-XTR-2162078 https://reactome.org/PathwayBrowser/#/R-XTR-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Xenopus tropicalis 11163 R-BTA-9708759 https://reactome.org/PathwayBrowser/#/R-BTA-9708759 DHODH:FMN binds DHODH inhibitors IEA Bos taurus 11163 R-CEL-9708759 https://reactome.org/PathwayBrowser/#/R-CEL-9708759 DHODH:FMN binds DHODH inhibitors IEA Caenorhabditis elegans 11163 R-CFA-9708759 https://reactome.org/PathwayBrowser/#/R-CFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Canis familiaris 11163 R-DME-9708759 https://reactome.org/PathwayBrowser/#/R-DME-9708759 DHODH:FMN binds DHODH inhibitors IEA Drosophila melanogaster 11163 R-DRE-9708759 https://reactome.org/PathwayBrowser/#/R-DRE-9708759 DHODH:FMN binds DHODH inhibitors IEA Danio rerio 11163 R-GGA-9708759 https://reactome.org/PathwayBrowser/#/R-GGA-9708759 DHODH:FMN binds DHODH inhibitors IEA Gallus gallus 11163 R-HSA-9708759 https://reactome.org/PathwayBrowser/#/R-HSA-9708759 DHODH:FMN binds DHODH inhibitors TAS Homo sapiens 11163 R-MMU-9708759 https://reactome.org/PathwayBrowser/#/R-MMU-9708759 DHODH:FMN binds DHODH inhibitors IEA Mus musculus 11163 R-PFA-9708759 https://reactome.org/PathwayBrowser/#/R-PFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Plasmodium falciparum 11163 R-RNO-9708759 https://reactome.org/PathwayBrowser/#/R-RNO-9708759 DHODH:FMN binds DHODH inhibitors IEA Rattus norvegicus 11163 R-SPO-9708759 https://reactome.org/PathwayBrowser/#/R-SPO-9708759 DHODH:FMN binds DHODH inhibitors IEA Schizosaccharomyces pombe 11163 R-SSC-9708759 https://reactome.org/PathwayBrowser/#/R-SSC-9708759 DHODH:FMN binds DHODH inhibitors IEA Sus scrofa 11163 R-XTR-9708759 https://reactome.org/PathwayBrowser/#/R-XTR-9708759 DHODH:FMN binds DHODH inhibitors IEA Xenopus tropicalis 11164 R-BTA-9708759 https://reactome.org/PathwayBrowser/#/R-BTA-9708759 DHODH:FMN binds DHODH inhibitors IEA Bos taurus 11164 R-CEL-9708759 https://reactome.org/PathwayBrowser/#/R-CEL-9708759 DHODH:FMN binds DHODH inhibitors IEA Caenorhabditis elegans 11164 R-CFA-9708759 https://reactome.org/PathwayBrowser/#/R-CFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Canis familiaris 11164 R-DME-9708759 https://reactome.org/PathwayBrowser/#/R-DME-9708759 DHODH:FMN binds DHODH inhibitors IEA Drosophila melanogaster 11164 R-DRE-9708759 https://reactome.org/PathwayBrowser/#/R-DRE-9708759 DHODH:FMN binds DHODH inhibitors IEA Danio rerio 11164 R-GGA-9708759 https://reactome.org/PathwayBrowser/#/R-GGA-9708759 DHODH:FMN binds DHODH inhibitors IEA Gallus gallus 11164 R-HSA-9708759 https://reactome.org/PathwayBrowser/#/R-HSA-9708759 DHODH:FMN binds DHODH inhibitors TAS Homo sapiens 11164 R-MMU-9708759 https://reactome.org/PathwayBrowser/#/R-MMU-9708759 DHODH:FMN binds DHODH inhibitors IEA Mus musculus 11164 R-PFA-9708759 https://reactome.org/PathwayBrowser/#/R-PFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Plasmodium falciparum 11164 R-RNO-9708759 https://reactome.org/PathwayBrowser/#/R-RNO-9708759 DHODH:FMN binds DHODH inhibitors IEA Rattus norvegicus 11164 R-SPO-9708759 https://reactome.org/PathwayBrowser/#/R-SPO-9708759 DHODH:FMN binds DHODH inhibitors IEA Schizosaccharomyces pombe 11164 R-SSC-9708759 https://reactome.org/PathwayBrowser/#/R-SSC-9708759 DHODH:FMN binds DHODH inhibitors IEA Sus scrofa 11164 R-XTR-9708759 https://reactome.org/PathwayBrowser/#/R-XTR-9708759 DHODH:FMN binds DHODH inhibitors IEA Xenopus tropicalis 11167 R-HSA-5340560 https://reactome.org/PathwayBrowser/#/R-HSA-5340560 PORCN-inhibitor LGK974 prevents WNT ligand palmitoyltation and secretion TAS Homo sapiens 11189 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 11189 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 11189 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 11189 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 11189 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 11189 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 11189 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 11189 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 11189 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 11189 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 11189 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 11189 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 11189 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 11189 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 11189 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 11189 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 11189 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 11189 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 11189 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 11189 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 11189 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 11189 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 11189 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 11189 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 11189 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 11189 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 11189 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 11189 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 11189 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 11215 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 11215 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 11215 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 11215 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 11215 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 11215 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 11215 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 11215 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 11215 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 11215 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 11215 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 11236 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 11236 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 11237 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 11237 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 11243 R-HSA-3139027 https://reactome.org/PathwayBrowser/#/R-HSA-3139027 Maturation of HIV Virion TAS Homo sapiens 11243 R-HSA-9697043 https://reactome.org/PathwayBrowser/#/R-HSA-9697043 Protease binds protease inhibitors TAS Homo sapiens 11244 R-HSA-164504 https://reactome.org/PathwayBrowser/#/R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) TAS Homo sapiens 11244 R-HSA-9697051 https://reactome.org/PathwayBrowser/#/R-HSA-9697051 RTC binds NRTIs TAS Homo sapiens 11250 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 11250 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 11250 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 11250 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 11250 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 11250 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 11250 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 11250 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 11273 R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 11320 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 11320 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 11325 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 11325 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 1133 R-BTA-9728664 https://reactome.org/PathwayBrowser/#/R-BTA-9728664 GLP1R binds GLP1R agonists IEA Bos taurus 1133 R-CFA-9728664 https://reactome.org/PathwayBrowser/#/R-CFA-9728664 GLP1R binds GLP1R agonists IEA Canis familiaris 1133 R-DRE-9728664 https://reactome.org/PathwayBrowser/#/R-DRE-9728664 GLP1R binds GLP1R agonists IEA Danio rerio 1133 R-HSA-9728664 https://reactome.org/PathwayBrowser/#/R-HSA-9728664 GLP1R binds GLP1R agonists TAS Homo sapiens 1133 R-MMU-9728664 https://reactome.org/PathwayBrowser/#/R-MMU-9728664 GLP1R binds GLP1R agonists IEA Mus musculus 1133 R-RNO-9728664 https://reactome.org/PathwayBrowser/#/R-RNO-9728664 GLP1R binds GLP1R agonists IEA Rattus norvegicus 1133 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa 11331 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 11331 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 1135 R-BTA-9728664 https://reactome.org/PathwayBrowser/#/R-BTA-9728664 GLP1R binds GLP1R agonists IEA Bos taurus 1135 R-CFA-9728664 https://reactome.org/PathwayBrowser/#/R-CFA-9728664 GLP1R binds GLP1R agonists IEA Canis familiaris 1135 R-DRE-9728664 https://reactome.org/PathwayBrowser/#/R-DRE-9728664 GLP1R binds GLP1R agonists IEA Danio rerio 1135 R-HSA-9728664 https://reactome.org/PathwayBrowser/#/R-HSA-9728664 GLP1R binds GLP1R agonists TAS Homo sapiens 1135 R-MMU-9728664 https://reactome.org/PathwayBrowser/#/R-MMU-9728664 GLP1R binds GLP1R agonists IEA Mus musculus 1135 R-RNO-9728664 https://reactome.org/PathwayBrowser/#/R-RNO-9728664 GLP1R binds GLP1R agonists IEA Rattus norvegicus 1135 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa 11503 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 11503 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 11503 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 11503 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 11503 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 11503 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 11503 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 11503 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 11569 R-BTA-9707186 https://reactome.org/PathwayBrowser/#/R-BTA-9707186 ALOX5 binds ALOX5 inhibitors IEA Bos taurus 11569 R-CFA-9707186 https://reactome.org/PathwayBrowser/#/R-CFA-9707186 ALOX5 binds ALOX5 inhibitors IEA Canis familiaris 11569 R-DDI-9707186 https://reactome.org/PathwayBrowser/#/R-DDI-9707186 ALOX5 binds ALOX5 inhibitors IEA Dictyostelium discoideum 11569 R-GGA-9707186 https://reactome.org/PathwayBrowser/#/R-GGA-9707186 ALOX5 binds ALOX5 inhibitors IEA Gallus gallus 11569 R-HSA-9707186 https://reactome.org/PathwayBrowser/#/R-HSA-9707186 ALOX5 binds ALOX5 inhibitors TAS Homo sapiens 11569 R-MMU-9707186 https://reactome.org/PathwayBrowser/#/R-MMU-9707186 ALOX5 binds ALOX5 inhibitors IEA Mus musculus 11569 R-RNO-9707186 https://reactome.org/PathwayBrowser/#/R-RNO-9707186 ALOX5 binds ALOX5 inhibitors IEA Rattus norvegicus 11569 R-SSC-9707186 https://reactome.org/PathwayBrowser/#/R-SSC-9707186 ALOX5 binds ALOX5 inhibitors IEA Sus scrofa 11569 R-XTR-9707186 https://reactome.org/PathwayBrowser/#/R-XTR-9707186 ALOX5 binds ALOX5 inhibitors IEA Xenopus tropicalis 11570 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 11570 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 11570 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 11570 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 11570 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 11570 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 11570 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 11570 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 11570 R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 11571 R-HSA-9731708 https://reactome.org/PathwayBrowser/#/R-HSA-9731708 nsp10:nsp14 binds to ExoN inhibitors TAS Homo sapiens 11572 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 11572 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 11572 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 11572 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 11572 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 11572 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 11572 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 11572 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 11573 R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 11576 R-BTA-9701064 https://reactome.org/PathwayBrowser/#/R-BTA-9701064 TRPV1 binds TRPV1 agonists IEA Bos taurus 11576 R-CEL-9701064 https://reactome.org/PathwayBrowser/#/R-CEL-9701064 TRPV1 binds TRPV1 agonists IEA Caenorhabditis elegans 11576 R-CFA-9701064 https://reactome.org/PathwayBrowser/#/R-CFA-9701064 TRPV1 binds TRPV1 agonists IEA Canis familiaris 11576 R-DME-9701064 https://reactome.org/PathwayBrowser/#/R-DME-9701064 TRPV1 binds TRPV1 agonists IEA Drosophila melanogaster 11576 R-DRE-9701064 https://reactome.org/PathwayBrowser/#/R-DRE-9701064 TRPV1 binds TRPV1 agonists IEA Danio rerio 11576 R-GGA-9701064 https://reactome.org/PathwayBrowser/#/R-GGA-9701064 TRPV1 binds TRPV1 agonists IEA Gallus gallus 11576 R-HSA-9701064 https://reactome.org/PathwayBrowser/#/R-HSA-9701064 TRPV1 binds TRPV1 agonists TAS Homo sapiens 11576 R-MMU-9701064 https://reactome.org/PathwayBrowser/#/R-MMU-9701064 TRPV1 binds TRPV1 agonists IEA Mus musculus 11576 R-RNO-9701064 https://reactome.org/PathwayBrowser/#/R-RNO-9701064 TRPV1 binds TRPV1 agonists IEA Rattus norvegicus 11576 R-SCE-9701064 https://reactome.org/PathwayBrowser/#/R-SCE-9701064 TRPV1 binds TRPV1 agonists IEA Saccharomyces cerevisiae 11576 R-SSC-9701064 https://reactome.org/PathwayBrowser/#/R-SSC-9701064 TRPV1 binds TRPV1 agonists IEA Sus scrofa 11576 R-XTR-9701064 https://reactome.org/PathwayBrowser/#/R-XTR-9701064 TRPV1 binds TRPV1 agonists IEA Xenopus tropicalis 11577 R-BTA-9708104 https://reactome.org/PathwayBrowser/#/R-BTA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Bos taurus 11577 R-CFA-9708104 https://reactome.org/PathwayBrowser/#/R-CFA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Canis familiaris 11577 R-DME-9708104 https://reactome.org/PathwayBrowser/#/R-DME-9708104 PDE5A dimer binds PDE5A inhibitors IEA Drosophila melanogaster 11577 R-GGA-9708104 https://reactome.org/PathwayBrowser/#/R-GGA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Gallus gallus 11577 R-HSA-9708104 https://reactome.org/PathwayBrowser/#/R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors TAS Homo sapiens 11577 R-MMU-9708104 https://reactome.org/PathwayBrowser/#/R-MMU-9708104 PDE5A dimer binds PDE5A inhibitors IEA Mus musculus 11577 R-RNO-9708104 https://reactome.org/PathwayBrowser/#/R-RNO-9708104 PDE5A dimer binds PDE5A inhibitors IEA Rattus norvegicus 11577 R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa 11577 R-XTR-9708104 https://reactome.org/PathwayBrowser/#/R-XTR-9708104 PDE5A dimer binds PDE5A inhibitors IEA Xenopus tropicalis 11578 R-BTA-9707186 https://reactome.org/PathwayBrowser/#/R-BTA-9707186 ALOX5 binds ALOX5 inhibitors IEA Bos taurus 11578 R-CFA-9707186 https://reactome.org/PathwayBrowser/#/R-CFA-9707186 ALOX5 binds ALOX5 inhibitors IEA Canis familiaris 11578 R-DDI-9707186 https://reactome.org/PathwayBrowser/#/R-DDI-9707186 ALOX5 binds ALOX5 inhibitors IEA Dictyostelium discoideum 11578 R-GGA-9707186 https://reactome.org/PathwayBrowser/#/R-GGA-9707186 ALOX5 binds ALOX5 inhibitors IEA Gallus gallus 11578 R-HSA-9707186 https://reactome.org/PathwayBrowser/#/R-HSA-9707186 ALOX5 binds ALOX5 inhibitors TAS Homo sapiens 11578 R-MMU-9707186 https://reactome.org/PathwayBrowser/#/R-MMU-9707186 ALOX5 binds ALOX5 inhibitors IEA Mus musculus 11578 R-RNO-9707186 https://reactome.org/PathwayBrowser/#/R-RNO-9707186 ALOX5 binds ALOX5 inhibitors IEA Rattus norvegicus 11578 R-SSC-9707186 https://reactome.org/PathwayBrowser/#/R-SSC-9707186 ALOX5 binds ALOX5 inhibitors IEA Sus scrofa 11578 R-XTR-9707186 https://reactome.org/PathwayBrowser/#/R-XTR-9707186 ALOX5 binds ALOX5 inhibitors IEA Xenopus tropicalis 11579 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 11579 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 11579 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 11579 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 11579 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 11579 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 11579 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 11579 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 11580 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 11580 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 11580 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 11580 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 11580 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 11580 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 11580 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 11580 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 11580 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 11580 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 11580 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 11580 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 11580 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 11580 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 11580 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 11580 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 11580 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 11580 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 11580 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 11580 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 11580 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 11580 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 11580 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 11581 R-HSA-2077421 https://reactome.org/PathwayBrowser/#/R-HSA-2077421 FP-1039 acts as a ligand-trap for FGFR2b-binding ligands in endometrial cancer TAS Homo sapiens 11582 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 11582 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 11582 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 11582 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 11582 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 11582 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 11582 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 11582 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 11582 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 11582 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 11582 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 11582 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 11738 R-BTA-9708104 https://reactome.org/PathwayBrowser/#/R-BTA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Bos taurus 11738 R-CFA-9708104 https://reactome.org/PathwayBrowser/#/R-CFA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Canis familiaris 11738 R-DME-9708104 https://reactome.org/PathwayBrowser/#/R-DME-9708104 PDE5A dimer binds PDE5A inhibitors IEA Drosophila melanogaster 11738 R-GGA-9708104 https://reactome.org/PathwayBrowser/#/R-GGA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Gallus gallus 11738 R-HSA-9708104 https://reactome.org/PathwayBrowser/#/R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors TAS Homo sapiens 11738 R-MMU-9708104 https://reactome.org/PathwayBrowser/#/R-MMU-9708104 PDE5A dimer binds PDE5A inhibitors IEA Mus musculus 11738 R-RNO-9708104 https://reactome.org/PathwayBrowser/#/R-RNO-9708104 PDE5A dimer binds PDE5A inhibitors IEA Rattus norvegicus 11738 R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa 11738 R-XTR-9708104 https://reactome.org/PathwayBrowser/#/R-XTR-9708104 PDE5A dimer binds PDE5A inhibitors IEA Xenopus tropicalis 11739 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 11739 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 11739 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 11739 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 11739 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 11739 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 11739 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 11739 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 11739 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 11739 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 11739 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 11739 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 11739 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 11739 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 11739 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 11740 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 11740 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 11740 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 11740 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 11740 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 11740 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 11740 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 11740 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 11740 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 11740 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 11741 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 11741 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 11741 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 11741 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 11741 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 11741 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 11741 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 11741 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 11741 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 11741 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 11742 R-BTA-9677917 https://reactome.org/PathwayBrowser/#/R-BTA-9677917 MAOA inhibitors bind MAOA:FAD IEA Bos taurus 11742 R-CFA-9677917 https://reactome.org/PathwayBrowser/#/R-CFA-9677917 MAOA inhibitors bind MAOA:FAD IEA Canis familiaris 11742 R-DDI-9677917 https://reactome.org/PathwayBrowser/#/R-DDI-9677917 MAOA inhibitors bind MAOA:FAD IEA Dictyostelium discoideum 11742 R-GGA-9677917 https://reactome.org/PathwayBrowser/#/R-GGA-9677917 MAOA inhibitors bind MAOA:FAD IEA Gallus gallus 11742 R-HSA-9677917 https://reactome.org/PathwayBrowser/#/R-HSA-9677917 MAOA inhibitors bind MAOA:FAD TAS Homo sapiens 11742 R-MMU-9677917 https://reactome.org/PathwayBrowser/#/R-MMU-9677917 MAOA inhibitors bind MAOA:FAD IEA Mus musculus 11742 R-RNO-9677917 https://reactome.org/PathwayBrowser/#/R-RNO-9677917 MAOA inhibitors bind MAOA:FAD IEA Rattus norvegicus 11742 R-SSC-9677917 https://reactome.org/PathwayBrowser/#/R-SSC-9677917 MAOA inhibitors bind MAOA:FAD IEA Sus scrofa 11744 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 11744 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 11744 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 11744 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 11744 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 11744 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 11744 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 11744 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 11744 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 11744 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 11745 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 11745 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 11745 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 11745 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 11745 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 11745 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 11745 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 11745 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 11745 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 11745 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 1175 R-BTA-9718360 https://reactome.org/PathwayBrowser/#/R-BTA-9718360 GNRHR binds GNRHR peptide agonists IEA Bos taurus 1175 R-CEL-9718360 https://reactome.org/PathwayBrowser/#/R-CEL-9718360 GNRHR binds GNRHR peptide agonists IEA Caenorhabditis elegans 1175 R-CFA-9718360 https://reactome.org/PathwayBrowser/#/R-CFA-9718360 GNRHR binds GNRHR peptide agonists IEA Canis familiaris 1175 R-DME-9718360 https://reactome.org/PathwayBrowser/#/R-DME-9718360 GNRHR binds GNRHR peptide agonists IEA Drosophila melanogaster 1175 R-DRE-9718360 https://reactome.org/PathwayBrowser/#/R-DRE-9718360 GNRHR binds GNRHR peptide agonists IEA Danio rerio 1175 R-GGA-9718360 https://reactome.org/PathwayBrowser/#/R-GGA-9718360 GNRHR binds GNRHR peptide agonists IEA Gallus gallus 1175 R-HSA-9718360 https://reactome.org/PathwayBrowser/#/R-HSA-9718360 GNRHR binds GNRHR peptide agonists TAS Homo sapiens 1175 R-MMU-9718360 https://reactome.org/PathwayBrowser/#/R-MMU-9718360 GNRHR binds GNRHR peptide agonists IEA Mus musculus 1175 R-RNO-9718360 https://reactome.org/PathwayBrowser/#/R-RNO-9718360 GNRHR binds GNRHR peptide agonists IEA Rattus norvegicus 1175 R-SSC-9718360 https://reactome.org/PathwayBrowser/#/R-SSC-9718360 GNRHR binds GNRHR peptide agonists IEA Sus scrofa 1175 R-XTR-9718360 https://reactome.org/PathwayBrowser/#/R-XTR-9718360 GNRHR binds GNRHR peptide agonists IEA Xenopus tropicalis 1177 R-BTA-9718360 https://reactome.org/PathwayBrowser/#/R-BTA-9718360 GNRHR binds GNRHR peptide agonists IEA Bos taurus 1177 R-CEL-9718360 https://reactome.org/PathwayBrowser/#/R-CEL-9718360 GNRHR binds GNRHR peptide agonists IEA Caenorhabditis elegans 1177 R-CFA-9718360 https://reactome.org/PathwayBrowser/#/R-CFA-9718360 GNRHR binds GNRHR peptide agonists IEA Canis familiaris 1177 R-DME-9718360 https://reactome.org/PathwayBrowser/#/R-DME-9718360 GNRHR binds GNRHR peptide agonists IEA Drosophila melanogaster 1177 R-DRE-9718360 https://reactome.org/PathwayBrowser/#/R-DRE-9718360 GNRHR binds GNRHR peptide agonists IEA Danio rerio 1177 R-GGA-9718360 https://reactome.org/PathwayBrowser/#/R-GGA-9718360 GNRHR binds GNRHR peptide agonists IEA Gallus gallus 1177 R-HSA-9718360 https://reactome.org/PathwayBrowser/#/R-HSA-9718360 GNRHR binds GNRHR peptide agonists TAS Homo sapiens 1177 R-MMU-9718360 https://reactome.org/PathwayBrowser/#/R-MMU-9718360 GNRHR binds GNRHR peptide agonists IEA Mus musculus 1177 R-RNO-9718360 https://reactome.org/PathwayBrowser/#/R-RNO-9718360 GNRHR binds GNRHR peptide agonists IEA Rattus norvegicus 1177 R-SSC-9718360 https://reactome.org/PathwayBrowser/#/R-SSC-9718360 GNRHR binds GNRHR peptide agonists IEA Sus scrofa 1177 R-XTR-9718360 https://reactome.org/PathwayBrowser/#/R-XTR-9718360 GNRHR binds GNRHR peptide agonists IEA Xenopus tropicalis 1188 R-BTA-9718394 https://reactome.org/PathwayBrowser/#/R-BTA-9718394 GNRHR binds GNRHR peptide antagonists IEA Bos taurus 1188 R-CEL-9718394 https://reactome.org/PathwayBrowser/#/R-CEL-9718394 GNRHR binds GNRHR peptide antagonists IEA Caenorhabditis elegans 1188 R-CFA-9718394 https://reactome.org/PathwayBrowser/#/R-CFA-9718394 GNRHR binds GNRHR peptide antagonists IEA Canis familiaris 1188 R-DME-9718394 https://reactome.org/PathwayBrowser/#/R-DME-9718394 GNRHR binds GNRHR peptide antagonists IEA Drosophila melanogaster 1188 R-DRE-9718394 https://reactome.org/PathwayBrowser/#/R-DRE-9718394 GNRHR binds GNRHR peptide antagonists IEA Danio rerio 1188 R-GGA-9718394 https://reactome.org/PathwayBrowser/#/R-GGA-9718394 GNRHR binds GNRHR peptide antagonists IEA Gallus gallus 1188 R-HSA-9718394 https://reactome.org/PathwayBrowser/#/R-HSA-9718394 GNRHR binds GNRHR peptide antagonists TAS Homo sapiens 1188 R-MMU-9718394 https://reactome.org/PathwayBrowser/#/R-MMU-9718394 GNRHR binds GNRHR peptide antagonists IEA Mus musculus 1188 R-RNO-9718394 https://reactome.org/PathwayBrowser/#/R-RNO-9718394 GNRHR binds GNRHR peptide antagonists IEA Rattus norvegicus 1188 R-SSC-9718394 https://reactome.org/PathwayBrowser/#/R-SSC-9718394 GNRHR binds GNRHR peptide antagonists IEA Sus scrofa 1188 R-XTR-9718394 https://reactome.org/PathwayBrowser/#/R-XTR-9718394 GNRHR binds GNRHR peptide antagonists IEA Xenopus tropicalis 1190 R-BTA-9718394 https://reactome.org/PathwayBrowser/#/R-BTA-9718394 GNRHR binds GNRHR peptide antagonists IEA Bos taurus 1190 R-CEL-9718394 https://reactome.org/PathwayBrowser/#/R-CEL-9718394 GNRHR binds GNRHR peptide antagonists IEA Caenorhabditis elegans 1190 R-CFA-9718394 https://reactome.org/PathwayBrowser/#/R-CFA-9718394 GNRHR binds GNRHR peptide antagonists IEA Canis familiaris 1190 R-DME-9718394 https://reactome.org/PathwayBrowser/#/R-DME-9718394 GNRHR binds GNRHR peptide antagonists IEA Drosophila melanogaster 1190 R-DRE-9718394 https://reactome.org/PathwayBrowser/#/R-DRE-9718394 GNRHR binds GNRHR peptide antagonists IEA Danio rerio 1190 R-GGA-9718394 https://reactome.org/PathwayBrowser/#/R-GGA-9718394 GNRHR binds GNRHR peptide antagonists IEA Gallus gallus 1190 R-HSA-9718394 https://reactome.org/PathwayBrowser/#/R-HSA-9718394 GNRHR binds GNRHR peptide antagonists TAS Homo sapiens 1190 R-MMU-9718394 https://reactome.org/PathwayBrowser/#/R-MMU-9718394 GNRHR binds GNRHR peptide antagonists IEA Mus musculus 1190 R-RNO-9718394 https://reactome.org/PathwayBrowser/#/R-RNO-9718394 GNRHR binds GNRHR peptide antagonists IEA Rattus norvegicus 1190 R-SSC-9718394 https://reactome.org/PathwayBrowser/#/R-SSC-9718394 GNRHR binds GNRHR peptide antagonists IEA Sus scrofa 1190 R-XTR-9718394 https://reactome.org/PathwayBrowser/#/R-XTR-9718394 GNRHR binds GNRHR peptide antagonists IEA Xenopus tropicalis 11900 R-BTA-380608 https://reactome.org/PathwayBrowser/#/R-BTA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Bos taurus 11900 R-CEL-380608 https://reactome.org/PathwayBrowser/#/R-CEL-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Caenorhabditis elegans 11900 R-CFA-380608 https://reactome.org/PathwayBrowser/#/R-CFA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Canis familiaris 11900 R-DDI-380608 https://reactome.org/PathwayBrowser/#/R-DDI-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Dictyostelium discoideum 11900 R-DME-380608 https://reactome.org/PathwayBrowser/#/R-DME-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Drosophila melanogaster 11900 R-DRE-380608 https://reactome.org/PathwayBrowser/#/R-DRE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Danio rerio 11900 R-GGA-380608 https://reactome.org/PathwayBrowser/#/R-GGA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Gallus gallus 11900 R-HSA-380608 https://reactome.org/PathwayBrowser/#/R-HSA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid TAS Homo sapiens 11900 R-MMU-380608 https://reactome.org/PathwayBrowser/#/R-MMU-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Mus musculus 11900 R-RNO-380608 https://reactome.org/PathwayBrowser/#/R-RNO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Rattus norvegicus 11900 R-SCE-380608 https://reactome.org/PathwayBrowser/#/R-SCE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Saccharomyces cerevisiae 11900 R-SPO-380608 https://reactome.org/PathwayBrowser/#/R-SPO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Schizosaccharomyces pombe 11900 R-SSC-380608 https://reactome.org/PathwayBrowser/#/R-SSC-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Sus scrofa 11900 R-XTR-380608 https://reactome.org/PathwayBrowser/#/R-XTR-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Xenopus tropicalis 11986 R-BTA-9957021 https://reactome.org/PathwayBrowser/#/R-BTA-9957021 C3 binds C3 inhibitors IEA Bos taurus 11986 R-CFA-9957021 https://reactome.org/PathwayBrowser/#/R-CFA-9957021 C3 binds C3 inhibitors IEA Canis familiaris 11986 R-DRE-9957021 https://reactome.org/PathwayBrowser/#/R-DRE-9957021 C3 binds C3 inhibitors IEA Danio rerio 11986 R-GGA-9957021 https://reactome.org/PathwayBrowser/#/R-GGA-9957021 C3 binds C3 inhibitors IEA Gallus gallus 11986 R-HSA-9957021 https://reactome.org/PathwayBrowser/#/R-HSA-9957021 C3 binds C3 inhibitors TAS Homo sapiens 11986 R-MMU-9957021 https://reactome.org/PathwayBrowser/#/R-MMU-9957021 C3 binds C3 inhibitors IEA Mus musculus 11986 R-RNO-9957021 https://reactome.org/PathwayBrowser/#/R-RNO-9957021 C3 binds C3 inhibitors IEA Rattus norvegicus 11986 R-SSC-9957021 https://reactome.org/PathwayBrowser/#/R-SSC-9957021 C3 binds C3 inhibitors IEA Sus scrofa 11986 R-XTR-9957021 https://reactome.org/PathwayBrowser/#/R-XTR-9957021 C3 binds C3 inhibitors IEA Xenopus tropicalis 1222 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 1222 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 1222 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 1222 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 1222 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 1222 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 1222 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 1222 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 1224 R-BTA-9704297 https://reactome.org/PathwayBrowser/#/R-BTA-9704297 CHRM2 binds CHRM2 antagonists IEA Bos taurus 1224 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 1224 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 1224 R-CEL-9704297 https://reactome.org/PathwayBrowser/#/R-CEL-9704297 CHRM2 binds CHRM2 antagonists IEA Caenorhabditis elegans 1224 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 1224 R-CFA-9704297 https://reactome.org/PathwayBrowser/#/R-CFA-9704297 CHRM2 binds CHRM2 antagonists IEA Canis familiaris 1224 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 1224 R-DME-9704297 https://reactome.org/PathwayBrowser/#/R-DME-9704297 CHRM2 binds CHRM2 antagonists IEA Drosophila melanogaster 1224 R-DRE-9704297 https://reactome.org/PathwayBrowser/#/R-DRE-9704297 CHRM2 binds CHRM2 antagonists IEA Danio rerio 1224 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 1224 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 1224 R-GGA-9704297 https://reactome.org/PathwayBrowser/#/R-GGA-9704297 CHRM2 binds CHRM2 antagonists IEA Gallus gallus 1224 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 1224 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 1224 R-HSA-9704297 https://reactome.org/PathwayBrowser/#/R-HSA-9704297 CHRM2 binds CHRM2 antagonists TAS Homo sapiens 1224 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 1224 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 1224 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 1224 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 1224 R-MMU-9704297 https://reactome.org/PathwayBrowser/#/R-MMU-9704297 CHRM2 binds CHRM2 antagonists IEA Mus musculus 1224 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 1224 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 1224 R-RNO-9704297 https://reactome.org/PathwayBrowser/#/R-RNO-9704297 CHRM2 binds CHRM2 antagonists IEA Rattus norvegicus 1224 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 1224 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 1224 R-SSC-9704297 https://reactome.org/PathwayBrowser/#/R-SSC-9704297 CHRM2 binds CHRM2 antagonists IEA Sus scrofa 1224 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 1224 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 1224 R-XTR-9704297 https://reactome.org/PathwayBrowser/#/R-XTR-9704297 CHRM2 binds CHRM2 antagonists IEA Xenopus tropicalis 1225 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 1225 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 1225 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 1225 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 1225 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 1225 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 1225 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 1225 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 1225 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 1225 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 1225 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 1225 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 1225 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 1225 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 1225 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 1225 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 1225 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 1225 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 1225 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 1225 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 1225 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 1227 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 1227 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 1227 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 1227 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 1227 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 1227 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 1227 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 1227 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 1228 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 1228 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 1228 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 1228 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 1228 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 1228 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 1228 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 1228 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 1231 R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 1231 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 1231 R-BTA-561041 https://reactome.org/PathwayBrowser/#/R-BTA-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Bos taurus 1231 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 1231 R-BTA-9692738 https://reactome.org/PathwayBrowser/#/R-BTA-9692738 HRH2 binds HRH2 antagonists IEA Bos taurus 1231 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 1231 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans 1231 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 1231 R-CEL-9692738 https://reactome.org/PathwayBrowser/#/R-CEL-9692738 HRH2 binds HRH2 antagonists IEA Caenorhabditis elegans 1231 R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 1231 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 1231 R-CFA-561041 https://reactome.org/PathwayBrowser/#/R-CFA-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Canis familiaris 1231 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 1231 R-CFA-9692738 https://reactome.org/PathwayBrowser/#/R-CFA-9692738 HRH2 binds HRH2 antagonists IEA Canis familiaris 1231 R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 1231 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 1231 R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster 1231 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 1231 R-DME-9692738 https://reactome.org/PathwayBrowser/#/R-DME-9692738 HRH2 binds HRH2 antagonists IEA Drosophila melanogaster 1231 R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 1231 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 1231 R-DRE-561041 https://reactome.org/PathwayBrowser/#/R-DRE-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Danio rerio 1231 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 1231 R-DRE-9692738 https://reactome.org/PathwayBrowser/#/R-DRE-9692738 HRH2 binds HRH2 antagonists IEA Danio rerio 1231 R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 1231 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 1231 R-GGA-561041 https://reactome.org/PathwayBrowser/#/R-GGA-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Gallus gallus 1231 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 1231 R-GGA-9692738 https://reactome.org/PathwayBrowser/#/R-GGA-9692738 HRH2 binds HRH2 antagonists IEA Gallus gallus 1231 R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 1231 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 1231 R-HSA-561041 https://reactome.org/PathwayBrowser/#/R-HSA-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids TAS Homo sapiens 1231 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 1231 R-HSA-9692738 https://reactome.org/PathwayBrowser/#/R-HSA-9692738 HRH2 binds HRH2 antagonists TAS Homo sapiens 1231 R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 1231 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 1231 R-MMU-561041 https://reactome.org/PathwayBrowser/#/R-MMU-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Mus musculus 1231 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 1231 R-MMU-9692738 https://reactome.org/PathwayBrowser/#/R-MMU-9692738 HRH2 binds HRH2 antagonists IEA Mus musculus 1231 R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 1231 R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 1231 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 1231 R-RNO-561041 https://reactome.org/PathwayBrowser/#/R-RNO-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Rattus norvegicus 1231 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 1231 R-RNO-9692738 https://reactome.org/PathwayBrowser/#/R-RNO-9692738 HRH2 binds HRH2 antagonists IEA Rattus norvegicus 1231 R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 1231 R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 1231 R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 1231 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 1231 R-SSC-561041 https://reactome.org/PathwayBrowser/#/R-SSC-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Sus scrofa 1231 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 1231 R-SSC-9692738 https://reactome.org/PathwayBrowser/#/R-SSC-9692738 HRH2 binds HRH2 antagonists IEA Sus scrofa 1231 R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 1231 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 1231 R-XTR-561041 https://reactome.org/PathwayBrowser/#/R-XTR-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Xenopus tropicalis 1231 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 1231 R-XTR-9692738 https://reactome.org/PathwayBrowser/#/R-XTR-9692738 HRH2 binds HRH2 antagonists IEA Xenopus tropicalis 1234 R-BTA-9692738 https://reactome.org/PathwayBrowser/#/R-BTA-9692738 HRH2 binds HRH2 antagonists IEA Bos taurus 1234 R-CEL-9692738 https://reactome.org/PathwayBrowser/#/R-CEL-9692738 HRH2 binds HRH2 antagonists IEA Caenorhabditis elegans 1234 R-CFA-9692738 https://reactome.org/PathwayBrowser/#/R-CFA-9692738 HRH2 binds HRH2 antagonists IEA Canis familiaris 1234 R-DME-9692738 https://reactome.org/PathwayBrowser/#/R-DME-9692738 HRH2 binds HRH2 antagonists IEA Drosophila melanogaster 1234 R-DRE-9692738 https://reactome.org/PathwayBrowser/#/R-DRE-9692738 HRH2 binds HRH2 antagonists IEA Danio rerio 1234 R-GGA-9692738 https://reactome.org/PathwayBrowser/#/R-GGA-9692738 HRH2 binds HRH2 antagonists IEA Gallus gallus 1234 R-HSA-9692738 https://reactome.org/PathwayBrowser/#/R-HSA-9692738 HRH2 binds HRH2 antagonists TAS Homo sapiens 1234 R-MMU-9692738 https://reactome.org/PathwayBrowser/#/R-MMU-9692738 HRH2 binds HRH2 antagonists IEA Mus musculus 1234 R-RNO-9692738 https://reactome.org/PathwayBrowser/#/R-RNO-9692738 HRH2 binds HRH2 antagonists IEA Rattus norvegicus 1234 R-SSC-9692738 https://reactome.org/PathwayBrowser/#/R-SSC-9692738 HRH2 binds HRH2 antagonists IEA Sus scrofa 1234 R-XTR-9692738 https://reactome.org/PathwayBrowser/#/R-XTR-9692738 HRH2 binds HRH2 antagonists IEA Xenopus tropicalis 124 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 124 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 124 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 124 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 124 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 124 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 124 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 124 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 124 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 124 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 124 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 124 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 124 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 124 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 124 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 124 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 124 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 124 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 124 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 124 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 124 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 124 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 12432 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 12432 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 12432 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 12432 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 12432 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12432 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 12432 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 12432 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 12432 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 12432 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12432 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 12432 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 12432 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12432 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 12432 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 12432 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 12432 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 12432 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12432 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 12432 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 12432 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 12432 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 12432 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12432 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12432 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12432 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 12432 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 12432 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 12432 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 12432 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12432 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 12432 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 12432 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12432 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 12432 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 12432 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 12432 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 12432 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12432 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 12432 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 12432 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 12432 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 12438 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 12438 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 12438 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 12438 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 12438 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12438 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 12438 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 12438 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 12438 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 12438 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12438 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 12438 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 12438 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12438 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 12438 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 12438 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 12438 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 12438 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12438 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 12438 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 12438 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 12438 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 12438 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12438 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12438 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12438 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 12438 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 12438 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 12438 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 12438 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12438 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 12438 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 12438 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12438 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 12438 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 12438 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 12438 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 12438 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12438 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 12438 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 12438 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 12438 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 12454 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 12454 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 12454 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 12454 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 12454 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12454 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 12454 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 12454 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 12454 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 12454 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12454 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 12454 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 12454 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12454 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 12454 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 12454 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 12454 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 12454 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12454 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 12454 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 12454 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 12454 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 12454 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12454 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12454 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12454 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 12454 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 12454 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 12454 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 12454 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12454 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 12454 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 12454 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12454 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 12454 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 12454 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 12454 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 12454 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12454 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 12454 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 12454 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 12454 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 12458 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 12458 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 12458 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 12458 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 12458 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12458 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 12458 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 12458 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 12458 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 12458 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12458 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 12458 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 12458 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12458 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 12458 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 12458 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 12458 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 12458 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12458 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 12458 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 12458 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 12458 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 12458 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12458 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12458 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12458 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 12458 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 12458 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 12458 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 12458 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12458 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 12458 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 12458 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12458 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 12458 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 12458 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 12458 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 12458 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12458 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 12458 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 12458 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 12458 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 12459 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 12459 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 12459 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 12459 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 12459 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12459 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 12459 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 12459 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 12459 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 12459 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12459 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 12459 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 12459 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12459 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 12459 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 12459 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 12459 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 12459 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12459 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 12459 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 12459 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 12459 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 12459 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12459 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12459 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12459 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 12459 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 12459 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 12459 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 12459 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12459 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 12459 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 12459 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12459 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 12459 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 12459 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 12459 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 12459 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12459 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 12459 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 12459 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 12459 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 12460 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12460 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12460 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12460 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12460 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12460 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12460 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12460 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12460 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12460 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12468 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 12468 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 12468 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 12468 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 12468 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12468 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 12468 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 12468 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 12468 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 12468 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12468 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 12468 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 12468 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12468 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 12468 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 12468 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 12468 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 12468 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12468 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 12468 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 12468 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 12468 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 12468 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12468 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12468 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12468 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 12468 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 12468 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 12468 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 12468 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12468 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 12468 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 12468 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12468 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 12468 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 12468 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 12468 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 12468 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12468 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 12468 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 12468 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 12468 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 12496 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12496 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12496 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12496 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12496 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12496 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12496 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12496 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12496 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12496 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12498 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 12498 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 12498 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 12498 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 12498 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 12498 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 12498 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 12498 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 12498 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 12498 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 12498 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 12498 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 12498 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 12498 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 12498 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 12498 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 12498 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 12498 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 12498 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 12498 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 12498 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 12498 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 12498 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 12498 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 12498 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 12498 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 12498 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 12498 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 12498 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 12498 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 12498 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 12498 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 12498 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 12498 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 12498 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 12498 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 12498 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 12498 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 12498 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 12498 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 12498 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 12498 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 12631 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 12631 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 12631 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 12631 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 12631 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 12631 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 12631 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 12633 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 12633 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 12633 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 12633 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 12633 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 12633 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 12633 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 12761 R-BTA-174967 https://reactome.org/PathwayBrowser/#/R-BTA-174967 NAT2 acetylation IEA Bos taurus 12761 R-DRE-174967 https://reactome.org/PathwayBrowser/#/R-DRE-174967 NAT2 acetylation IEA Danio rerio 12761 R-GGA-174967 https://reactome.org/PathwayBrowser/#/R-GGA-174967 NAT2 acetylation IEA Gallus gallus 12761 R-HSA-174967 https://reactome.org/PathwayBrowser/#/R-HSA-174967 NAT2 acetylation TAS Homo sapiens 12761 R-MMU-174967 https://reactome.org/PathwayBrowser/#/R-MMU-174967 NAT2 acetylation IEA Mus musculus 12761 R-RNO-174967 https://reactome.org/PathwayBrowser/#/R-RNO-174967 NAT2 acetylation IEA Rattus norvegicus 12761 R-SSC-174967 https://reactome.org/PathwayBrowser/#/R-SSC-174967 NAT2 acetylation IEA Sus scrofa 12790 R-BTA-9691621 https://reactome.org/PathwayBrowser/#/R-BTA-9691621 C5 binds C5 inhibitors IEA Bos taurus 12790 R-CFA-9691621 https://reactome.org/PathwayBrowser/#/R-CFA-9691621 C5 binds C5 inhibitors IEA Canis familiaris 12790 R-GGA-9691621 https://reactome.org/PathwayBrowser/#/R-GGA-9691621 C5 binds C5 inhibitors IEA Gallus gallus 12790 R-HSA-9691621 https://reactome.org/PathwayBrowser/#/R-HSA-9691621 C5 binds C5 inhibitors TAS Homo sapiens 12790 R-MMU-9691621 https://reactome.org/PathwayBrowser/#/R-MMU-9691621 C5 binds C5 inhibitors IEA Mus musculus 12790 R-RNO-9691621 https://reactome.org/PathwayBrowser/#/R-RNO-9691621 C5 binds C5 inhibitors IEA Rattus norvegicus 12790 R-SSC-9691621 https://reactome.org/PathwayBrowser/#/R-SSC-9691621 C5 binds C5 inhibitors IEA Sus scrofa 12857 R-BTA-9691621 https://reactome.org/PathwayBrowser/#/R-BTA-9691621 C5 binds C5 inhibitors IEA Bos taurus 12857 R-CFA-9691621 https://reactome.org/PathwayBrowser/#/R-CFA-9691621 C5 binds C5 inhibitors IEA Canis familiaris 12857 R-GGA-9691621 https://reactome.org/PathwayBrowser/#/R-GGA-9691621 C5 binds C5 inhibitors IEA Gallus gallus 12857 R-HSA-9691621 https://reactome.org/PathwayBrowser/#/R-HSA-9691621 C5 binds C5 inhibitors TAS Homo sapiens 12857 R-MMU-9691621 https://reactome.org/PathwayBrowser/#/R-MMU-9691621 C5 binds C5 inhibitors IEA Mus musculus 12857 R-RNO-9691621 https://reactome.org/PathwayBrowser/#/R-RNO-9691621 C5 binds C5 inhibitors IEA Rattus norvegicus 12857 R-SSC-9691621 https://reactome.org/PathwayBrowser/#/R-SSC-9691621 C5 binds C5 inhibitors IEA Sus scrofa 12900 R-BTA-9691621 https://reactome.org/PathwayBrowser/#/R-BTA-9691621 C5 binds C5 inhibitors IEA Bos taurus 12900 R-CFA-9691621 https://reactome.org/PathwayBrowser/#/R-CFA-9691621 C5 binds C5 inhibitors IEA Canis familiaris 12900 R-GGA-9691621 https://reactome.org/PathwayBrowser/#/R-GGA-9691621 C5 binds C5 inhibitors IEA Gallus gallus 12900 R-HSA-9691621 https://reactome.org/PathwayBrowser/#/R-HSA-9691621 C5 binds C5 inhibitors TAS Homo sapiens 12900 R-MMU-9691621 https://reactome.org/PathwayBrowser/#/R-MMU-9691621 C5 binds C5 inhibitors IEA Mus musculus 12900 R-RNO-9691621 https://reactome.org/PathwayBrowser/#/R-RNO-9691621 C5 binds C5 inhibitors IEA Rattus norvegicus 12900 R-SSC-9691621 https://reactome.org/PathwayBrowser/#/R-SSC-9691621 C5 binds C5 inhibitors IEA Sus scrofa 13137 R-BTA-2396009 https://reactome.org/PathwayBrowser/#/R-BTA-2396009 STING binds c-di-GMP IEA Bos taurus 13137 R-BTA-9013869 https://reactome.org/PathwayBrowser/#/R-BTA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Bos taurus 13137 R-CEL-9013869 https://reactome.org/PathwayBrowser/#/R-CEL-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Caenorhabditis elegans 13137 R-CFA-9013869 https://reactome.org/PathwayBrowser/#/R-CFA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Canis familiaris 13137 R-DDI-9013869 https://reactome.org/PathwayBrowser/#/R-DDI-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Dictyostelium discoideum 13137 R-DME-2396009 https://reactome.org/PathwayBrowser/#/R-DME-2396009 STING binds c-di-GMP IEA Drosophila melanogaster 13137 R-DME-9013869 https://reactome.org/PathwayBrowser/#/R-DME-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Drosophila melanogaster 13137 R-DRE-2396009 https://reactome.org/PathwayBrowser/#/R-DRE-2396009 STING binds c-di-GMP IEA Danio rerio 13137 R-GGA-2396009 https://reactome.org/PathwayBrowser/#/R-GGA-2396009 STING binds c-di-GMP IEA Gallus gallus 13137 R-GGA-9013869 https://reactome.org/PathwayBrowser/#/R-GGA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Gallus gallus 13137 R-HSA-1834939 https://reactome.org/PathwayBrowser/#/R-HSA-1834939 STING recruits TBK1 and IRF3 TAS Homo sapiens 13137 R-HSA-2396009 https://reactome.org/PathwayBrowser/#/R-HSA-2396009 STING binds c-di-GMP TAS Homo sapiens 13137 R-HSA-9013869 https://reactome.org/PathwayBrowser/#/R-HSA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP TAS Homo sapiens 13137 R-MMU-2396009 https://reactome.org/PathwayBrowser/#/R-MMU-2396009 STING binds c-di-GMP IEA Mus musculus 13137 R-MMU-9013869 https://reactome.org/PathwayBrowser/#/R-MMU-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Mus musculus 13137 R-RNO-2396009 https://reactome.org/PathwayBrowser/#/R-RNO-2396009 STING binds c-di-GMP IEA Rattus norvegicus 13137 R-RNO-9013869 https://reactome.org/PathwayBrowser/#/R-RNO-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Rattus norvegicus 13137 R-SSC-2396009 https://reactome.org/PathwayBrowser/#/R-SSC-2396009 STING binds c-di-GMP IEA Sus scrofa 13137 R-SSC-9013869 https://reactome.org/PathwayBrowser/#/R-SSC-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Sus scrofa 13137 R-XTR-2396009 https://reactome.org/PathwayBrowser/#/R-XTR-2396009 STING binds c-di-GMP IEA Xenopus tropicalis 13137 R-XTR-9013869 https://reactome.org/PathwayBrowser/#/R-XTR-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP IEA Xenopus tropicalis 13147 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 13147 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 13147 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 13147 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 13147 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 13147 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 13147 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 13147 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 13147 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 13147 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 13147 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 13147 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 13147 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 13147 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 13147 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 13147 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 13147 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 13147 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 13147 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 13147 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 13147 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 13147 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 13147 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 13147 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 13147 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 13147 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 13147 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 13147 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 13147 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 13147 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 13147 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 13147 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 13147 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 13147 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 13147 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 13147 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 13147 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 13147 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 13147 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 13147 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 13147 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 13147 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 13597 R-HSA-9856737 https://reactome.org/PathwayBrowser/#/R-HSA-9856737 Unknown enzyme(s) process 4-HMA to 4-Hbz TAS Homo sapiens 13597 R-HSA-9856794 https://reactome.org/PathwayBrowser/#/R-HSA-9856794 Unknown dehydrogenase oxidizes 4-HBz IEA Homo sapiens 13597 R-SCE-9856799 https://reactome.org/PathwayBrowser/#/R-SCE-9856799 HFD1 oxidizes 4-HBz TAS Saccharomyces cerevisiae 13652 R-BTA-174963 https://reactome.org/PathwayBrowser/#/R-BTA-174963 NAT1 acetylation IEA Bos taurus 13652 R-DRE-174963 https://reactome.org/PathwayBrowser/#/R-DRE-174963 NAT1 acetylation IEA Danio rerio 13652 R-GGA-174963 https://reactome.org/PathwayBrowser/#/R-GGA-174963 NAT1 acetylation IEA Gallus gallus 13652 R-HSA-174963 https://reactome.org/PathwayBrowser/#/R-HSA-174963 NAT1 acetylation TAS Homo sapiens 13652 R-MMU-174963 https://reactome.org/PathwayBrowser/#/R-MMU-174963 NAT1 acetylation IEA Mus musculus 13652 R-RNO-174963 https://reactome.org/PathwayBrowser/#/R-RNO-174963 NAT1 acetylation IEA Rattus norvegicus 13652 R-SSC-174963 https://reactome.org/PathwayBrowser/#/R-SSC-174963 NAT1 acetylation IEA Sus scrofa 13826 R-BTA-9957021 https://reactome.org/PathwayBrowser/#/R-BTA-9957021 C3 binds C3 inhibitors IEA Bos taurus 13826 R-CFA-9957021 https://reactome.org/PathwayBrowser/#/R-CFA-9957021 C3 binds C3 inhibitors IEA Canis familiaris 13826 R-DRE-9957021 https://reactome.org/PathwayBrowser/#/R-DRE-9957021 C3 binds C3 inhibitors IEA Danio rerio 13826 R-GGA-9957021 https://reactome.org/PathwayBrowser/#/R-GGA-9957021 C3 binds C3 inhibitors IEA Gallus gallus 13826 R-HSA-9957021 https://reactome.org/PathwayBrowser/#/R-HSA-9957021 C3 binds C3 inhibitors TAS Homo sapiens 13826 R-MMU-9957021 https://reactome.org/PathwayBrowser/#/R-MMU-9957021 C3 binds C3 inhibitors IEA Mus musculus 13826 R-RNO-9957021 https://reactome.org/PathwayBrowser/#/R-RNO-9957021 C3 binds C3 inhibitors IEA Rattus norvegicus 13826 R-SSC-9957021 https://reactome.org/PathwayBrowser/#/R-SSC-9957021 C3 binds C3 inhibitors IEA Sus scrofa 13826 R-XTR-9957021 https://reactome.org/PathwayBrowser/#/R-XTR-9957021 C3 binds C3 inhibitors IEA Xenopus tropicalis 1456 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 1456 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 1456 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 1456 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 1456 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 1456 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 1456 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 1456 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 1456 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 1456 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 1456 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 1456 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 1456 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 1456 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 1456 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 1456 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 1456 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 1456 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 1456 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 1456 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 1593 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 1593 R-BTA-444661 https://reactome.org/PathwayBrowser/#/R-BTA-444661 HCAR2 binds HCAR2 ligands IEA Bos taurus 1593 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 1593 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 1593 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 1593 R-CFA-444661 https://reactome.org/PathwayBrowser/#/R-CFA-444661 HCAR2 binds HCAR2 ligands IEA Canis familiaris 1593 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 1593 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 1593 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 1593 R-DRE-444661 https://reactome.org/PathwayBrowser/#/R-DRE-444661 HCAR2 binds HCAR2 ligands IEA Danio rerio 1593 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 1593 R-HSA-444661 https://reactome.org/PathwayBrowser/#/R-HSA-444661 HCAR2 binds HCAR2 ligands TAS Homo sapiens 1593 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 1593 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 1593 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 1593 R-MMU-444661 https://reactome.org/PathwayBrowser/#/R-MMU-444661 HCAR2 binds HCAR2 ligands IEA Mus musculus 1593 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 1593 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 1593 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 1593 R-RNO-444661 https://reactome.org/PathwayBrowser/#/R-RNO-444661 HCAR2 binds HCAR2 ligands IEA Rattus norvegicus 1593 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 1593 R-SSC-444661 https://reactome.org/PathwayBrowser/#/R-SSC-444661 HCAR2 binds HCAR2 ligands IEA Sus scrofa 1593 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 1593 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 1728 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 1728 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 1728 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 1728 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 1728 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 1728 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 1728 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 1728 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 1732 R-BTA-9825788 https://reactome.org/PathwayBrowser/#/R-BTA-9825788 p-S207 KARS displaces HINT1 IEA Bos taurus 1732 R-BTA-9825790 https://reactome.org/PathwayBrowser/#/R-BTA-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Bos taurus 1732 R-CEL-9825788 https://reactome.org/PathwayBrowser/#/R-CEL-9825788 p-S207 KARS displaces HINT1 IEA Caenorhabditis elegans 1732 R-CEL-9825790 https://reactome.org/PathwayBrowser/#/R-CEL-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Caenorhabditis elegans 1732 R-CFA-9825788 https://reactome.org/PathwayBrowser/#/R-CFA-9825788 p-S207 KARS displaces HINT1 IEA Canis familiaris 1732 R-CFA-9825790 https://reactome.org/PathwayBrowser/#/R-CFA-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Canis familiaris 1732 R-DME-9825788 https://reactome.org/PathwayBrowser/#/R-DME-9825788 p-S207 KARS displaces HINT1 IEA Drosophila melanogaster 1732 R-DME-9825790 https://reactome.org/PathwayBrowser/#/R-DME-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Drosophila melanogaster 1732 R-DRE-9825788 https://reactome.org/PathwayBrowser/#/R-DRE-9825788 p-S207 KARS displaces HINT1 IEA Danio rerio 1732 R-DRE-9825790 https://reactome.org/PathwayBrowser/#/R-DRE-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Danio rerio 1732 R-GGA-9825788 https://reactome.org/PathwayBrowser/#/R-GGA-9825788 p-S207 KARS displaces HINT1 IEA Gallus gallus 1732 R-GGA-9825790 https://reactome.org/PathwayBrowser/#/R-GGA-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Gallus gallus 1732 R-HSA-9825788 https://reactome.org/PathwayBrowser/#/R-HSA-9825788 p-S207 KARS displaces HINT1 TAS Homo sapiens 1732 R-HSA-9825790 https://reactome.org/PathwayBrowser/#/R-HSA-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A TAS Homo sapiens 1732 R-MMU-9825788 https://reactome.org/PathwayBrowser/#/R-MMU-9825788 p-S207 KARS displaces HINT1 IEA Mus musculus 1732 R-MMU-9825790 https://reactome.org/PathwayBrowser/#/R-MMU-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Mus musculus 1732 R-RNO-9825788 https://reactome.org/PathwayBrowser/#/R-RNO-9825788 p-S207 KARS displaces HINT1 IEA Rattus norvegicus 1732 R-RNO-9825790 https://reactome.org/PathwayBrowser/#/R-RNO-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Rattus norvegicus 1732 R-SSC-9825788 https://reactome.org/PathwayBrowser/#/R-SSC-9825788 p-S207 KARS displaces HINT1 IEA Sus scrofa 1732 R-SSC-9825790 https://reactome.org/PathwayBrowser/#/R-SSC-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Sus scrofa 1742 R-BTA-1675883 https://reactome.org/PathwayBrowser/#/R-BTA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Bos taurus 1742 R-BTA-1676152 https://reactome.org/PathwayBrowser/#/R-BTA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Bos taurus 1742 R-BTA-2213248 https://reactome.org/PathwayBrowser/#/R-BTA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Bos taurus 1742 R-BTA-432237 https://reactome.org/PathwayBrowser/#/R-BTA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Bos taurus 1742 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 1742 R-BTA-5624127 https://reactome.org/PathwayBrowser/#/R-BTA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Bos taurus 1742 R-BTA-5624130 https://reactome.org/PathwayBrowser/#/R-BTA-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Bos taurus 1742 R-BTA-5624133 https://reactome.org/PathwayBrowser/#/R-BTA-5624133 ARL3:GTP binds the UNC119B complex IEA Bos taurus 1742 R-BTA-5624949 https://reactome.org/PathwayBrowser/#/R-BTA-5624949 Assembly of the anterograde IFT train IEA Bos taurus 1742 R-BTA-5625416 https://reactome.org/PathwayBrowser/#/R-BTA-5625416 Anterograde IFT IEA Bos taurus 1742 R-BTA-5625426 https://reactome.org/PathwayBrowser/#/R-BTA-5625426 Retrograde IFT IEA Bos taurus 1742 R-BTA-5638004 https://reactome.org/PathwayBrowser/#/R-BTA-5638004 RP2 binds ARL3:GTP:UNC119B IEA Bos taurus 1742 R-BTA-5638006 https://reactome.org/PathwayBrowser/#/R-BTA-5638006 ARL3 hydrolyzes GTP IEA Bos taurus 1742 R-BTA-5638007 https://reactome.org/PathwayBrowser/#/R-BTA-5638007 RP2 activates the GTPase activity of ARL3 IEA Bos taurus 1742 R-BTA-8847880 https://reactome.org/PathwayBrowser/#/R-BTA-8847880 CYTH proteins bind ARF1:GTP IEA Bos taurus 1742 R-BTA-8847883 https://reactome.org/PathwayBrowser/#/R-BTA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Bos taurus 1742 R-BTA-8854255 https://reactome.org/PathwayBrowser/#/R-BTA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Bos taurus 1742 R-BTA-8854329 https://reactome.org/PathwayBrowser/#/R-BTA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Bos taurus 1742 R-BTA-8854604 https://reactome.org/PathwayBrowser/#/R-BTA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Bos taurus 1742 R-BTA-8871366 https://reactome.org/PathwayBrowser/#/R-BTA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Bos taurus 1742 R-BTA-983422 https://reactome.org/PathwayBrowser/#/R-BTA-983422 Disassembly of COPII coated vesicle IEA Bos taurus 1742 R-BTA-983424 https://reactome.org/PathwayBrowser/#/R-BTA-983424 Budding of COPII coated vesicle IEA Bos taurus 1742 R-CEL-1675883 https://reactome.org/PathwayBrowser/#/R-CEL-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Caenorhabditis elegans 1742 R-CEL-1676152 https://reactome.org/PathwayBrowser/#/R-CEL-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Caenorhabditis elegans 1742 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 1742 R-CEL-5624127 https://reactome.org/PathwayBrowser/#/R-CEL-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Caenorhabditis elegans 1742 R-CEL-5625416 https://reactome.org/PathwayBrowser/#/R-CEL-5625416 Anterograde IFT IEA Caenorhabditis elegans 1742 R-CEL-5625426 https://reactome.org/PathwayBrowser/#/R-CEL-5625426 Retrograde IFT IEA Caenorhabditis elegans 1742 R-CEL-5638004 https://reactome.org/PathwayBrowser/#/R-CEL-5638004 RP2 binds ARL3:GTP:UNC119B IEA Caenorhabditis elegans 1742 R-CEL-5638006 https://reactome.org/PathwayBrowser/#/R-CEL-5638006 ARL3 hydrolyzes GTP IEA Caenorhabditis elegans 1742 R-CEL-5638007 https://reactome.org/PathwayBrowser/#/R-CEL-5638007 RP2 activates the GTPase activity of ARL3 IEA Caenorhabditis elegans 1742 R-CEL-8854222 https://reactome.org/PathwayBrowser/#/R-CEL-8854222 TBC1D3 associates with RAB5 IEA Caenorhabditis elegans 1742 R-CEL-8854255 https://reactome.org/PathwayBrowser/#/R-CEL-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 1742 R-CEL-8854329 https://reactome.org/PathwayBrowser/#/R-CEL-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 1742 R-CFA-1675883 https://reactome.org/PathwayBrowser/#/R-CFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Canis familiaris 1742 R-CFA-1676152 https://reactome.org/PathwayBrowser/#/R-CFA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Canis familiaris 1742 R-CFA-2213248 https://reactome.org/PathwayBrowser/#/R-CFA-2213248 Transport of antigen loaded MHC II molecules to surface IEA Canis familiaris 1742 R-CFA-432237 https://reactome.org/PathwayBrowser/#/R-CFA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Canis familiaris 1742 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 1742 R-CFA-5624127 https://reactome.org/PathwayBrowser/#/R-CFA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Canis familiaris 1742 R-CFA-5624130 https://reactome.org/PathwayBrowser/#/R-CFA-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Canis familiaris 1742 R-CFA-5624133 https://reactome.org/PathwayBrowser/#/R-CFA-5624133 ARL3:GTP binds the UNC119B complex IEA Canis familiaris 1742 R-CFA-5624949 https://reactome.org/PathwayBrowser/#/R-CFA-5624949 Assembly of the anterograde IFT train IEA Canis familiaris 1742 R-CFA-5624952 https://reactome.org/PathwayBrowser/#/R-CFA-5624952 Assembly of the retrograde IFT train IEA Canis familiaris 1742 R-CFA-5625416 https://reactome.org/PathwayBrowser/#/R-CFA-5625416 Anterograde IFT IEA Canis familiaris 1742 R-CFA-5625421 https://reactome.org/PathwayBrowser/#/R-CFA-5625421 The anterograde IFT train dissociates IEA Canis familiaris 1742 R-CFA-5625424 https://reactome.org/PathwayBrowser/#/R-CFA-5625424 The retrograde IFT train dissociates IEA Canis familiaris 1742 R-CFA-5625426 https://reactome.org/PathwayBrowser/#/R-CFA-5625426 Retrograde IFT IEA Canis familiaris 1742 R-CFA-5638004 https://reactome.org/PathwayBrowser/#/R-CFA-5638004 RP2 binds ARL3:GTP:UNC119B IEA Canis familiaris 1742 R-CFA-5638006 https://reactome.org/PathwayBrowser/#/R-CFA-5638006 ARL3 hydrolyzes GTP IEA Canis familiaris 1742 R-CFA-5638007 https://reactome.org/PathwayBrowser/#/R-CFA-5638007 RP2 activates the GTPase activity of ARL3 IEA Canis familiaris 1742 R-CFA-8847875 https://reactome.org/PathwayBrowser/#/R-CFA-8847875 ARF1:GTP binds Golgin TRIP11 IEA Canis familiaris 1742 R-CFA-8847880 https://reactome.org/PathwayBrowser/#/R-CFA-8847880 CYTH proteins bind ARF1:GTP IEA Canis familiaris 1742 R-CFA-8847883 https://reactome.org/PathwayBrowser/#/R-CFA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Canis familiaris 1742 R-CFA-8854255 https://reactome.org/PathwayBrowser/#/R-CFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 1742 R-CFA-8854329 https://reactome.org/PathwayBrowser/#/R-CFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 1742 R-CFA-8854604 https://reactome.org/PathwayBrowser/#/R-CFA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Canis familiaris 1742 R-CFA-983422 https://reactome.org/PathwayBrowser/#/R-CFA-983422 Disassembly of COPII coated vesicle IEA Canis familiaris 1742 R-CFA-983424 https://reactome.org/PathwayBrowser/#/R-CFA-983424 Budding of COPII coated vesicle IEA Canis familiaris 1742 R-DDI-1675883 https://reactome.org/PathwayBrowser/#/R-DDI-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Dictyostelium discoideum 1742 R-DDI-1676152 https://reactome.org/PathwayBrowser/#/R-DDI-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Dictyostelium discoideum 1742 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 1742 R-DDI-8847880 https://reactome.org/PathwayBrowser/#/R-DDI-8847880 CYTH proteins bind ARF1:GTP IEA Dictyostelium discoideum 1742 R-DDI-8847883 https://reactome.org/PathwayBrowser/#/R-DDI-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Dictyostelium discoideum 1742 R-DDI-8854255 https://reactome.org/PathwayBrowser/#/R-DDI-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 1742 R-DDI-8854329 https://reactome.org/PathwayBrowser/#/R-DDI-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 1742 R-DDI-8854604 https://reactome.org/PathwayBrowser/#/R-DDI-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Dictyostelium discoideum 1742 R-DME-1675883 https://reactome.org/PathwayBrowser/#/R-DME-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Drosophila melanogaster 1742 R-DME-1676152 https://reactome.org/PathwayBrowser/#/R-DME-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Drosophila melanogaster 1742 R-DME-432237 https://reactome.org/PathwayBrowser/#/R-DME-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Drosophila melanogaster 1742 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 1742 R-DME-8847875 https://reactome.org/PathwayBrowser/#/R-DME-8847875 ARF1:GTP binds Golgin TRIP11 IEA Drosophila melanogaster 1742 R-DME-8847880 https://reactome.org/PathwayBrowser/#/R-DME-8847880 CYTH proteins bind ARF1:GTP IEA Drosophila melanogaster 1742 R-DME-8847883 https://reactome.org/PathwayBrowser/#/R-DME-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Drosophila melanogaster 1742 R-DME-8854222 https://reactome.org/PathwayBrowser/#/R-DME-8854222 TBC1D3 associates with RAB5 IEA Drosophila melanogaster 1742 R-DME-8854255 https://reactome.org/PathwayBrowser/#/R-DME-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 1742 R-DME-8854329 https://reactome.org/PathwayBrowser/#/R-DME-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 1742 R-DME-8854604 https://reactome.org/PathwayBrowser/#/R-DME-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Drosophila melanogaster 1742 R-DME-8871366 https://reactome.org/PathwayBrowser/#/R-DME-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Drosophila melanogaster 1742 R-DRE-1675883 https://reactome.org/PathwayBrowser/#/R-DRE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Danio rerio 1742 R-DRE-1676152 https://reactome.org/PathwayBrowser/#/R-DRE-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Danio rerio 1742 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 1742 R-DRE-5624130 https://reactome.org/PathwayBrowser/#/R-DRE-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Danio rerio 1742 R-DRE-5624133 https://reactome.org/PathwayBrowser/#/R-DRE-5624133 ARL3:GTP binds the UNC119B complex IEA Danio rerio 1742 R-DRE-5638004 https://reactome.org/PathwayBrowser/#/R-DRE-5638004 RP2 binds ARL3:GTP:UNC119B IEA Danio rerio 1742 R-DRE-5638006 https://reactome.org/PathwayBrowser/#/R-DRE-5638006 ARL3 hydrolyzes GTP IEA Danio rerio 1742 R-DRE-5638007 https://reactome.org/PathwayBrowser/#/R-DRE-5638007 RP2 activates the GTPase activity of ARL3 IEA Danio rerio 1742 R-DRE-8854255 https://reactome.org/PathwayBrowser/#/R-DRE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Danio rerio 1742 R-DRE-8854329 https://reactome.org/PathwayBrowser/#/R-DRE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Danio rerio 1742 R-DRE-8854604 https://reactome.org/PathwayBrowser/#/R-DRE-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Danio rerio 1742 R-DRE-983424 https://reactome.org/PathwayBrowser/#/R-DRE-983424 Budding of COPII coated vesicle IEA Danio rerio 1742 R-GGA-1675883 https://reactome.org/PathwayBrowser/#/R-GGA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Gallus gallus 1742 R-GGA-1676152 https://reactome.org/PathwayBrowser/#/R-GGA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Gallus gallus 1742 R-GGA-432237 https://reactome.org/PathwayBrowser/#/R-GGA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Gallus gallus 1742 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 1742 R-GGA-5624127 https://reactome.org/PathwayBrowser/#/R-GGA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Gallus gallus 1742 R-GGA-5624949 https://reactome.org/PathwayBrowser/#/R-GGA-5624949 Assembly of the anterograde IFT train IEA Gallus gallus 1742 R-GGA-5625416 https://reactome.org/PathwayBrowser/#/R-GGA-5625416 Anterograde IFT IEA Gallus gallus 1742 R-GGA-5625426 https://reactome.org/PathwayBrowser/#/R-GGA-5625426 Retrograde IFT IEA Gallus gallus 1742 R-GGA-5638004 https://reactome.org/PathwayBrowser/#/R-GGA-5638004 RP2 binds ARL3:GTP:UNC119B IEA Gallus gallus 1742 R-GGA-5638006 https://reactome.org/PathwayBrowser/#/R-GGA-5638006 ARL3 hydrolyzes GTP IEA Gallus gallus 1742 R-GGA-5638007 https://reactome.org/PathwayBrowser/#/R-GGA-5638007 RP2 activates the GTPase activity of ARL3 IEA Gallus gallus 1742 R-GGA-8847875 https://reactome.org/PathwayBrowser/#/R-GGA-8847875 ARF1:GTP binds Golgin TRIP11 IEA Gallus gallus 1742 R-GGA-8847880 https://reactome.org/PathwayBrowser/#/R-GGA-8847880 CYTH proteins bind ARF1:GTP IEA Gallus gallus 1742 R-GGA-8847883 https://reactome.org/PathwayBrowser/#/R-GGA-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Gallus gallus 1742 R-GGA-8854222 https://reactome.org/PathwayBrowser/#/R-GGA-8854222 TBC1D3 associates with RAB5 IEA Gallus gallus 1742 R-GGA-8854255 https://reactome.org/PathwayBrowser/#/R-GGA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 1742 R-GGA-8854329 https://reactome.org/PathwayBrowser/#/R-GGA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 1742 R-GGA-8854604 https://reactome.org/PathwayBrowser/#/R-GGA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Gallus gallus 1742 R-GGA-8871366 https://reactome.org/PathwayBrowser/#/R-GGA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Gallus gallus 1742 R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus 1742 R-GGA-983424 https://reactome.org/PathwayBrowser/#/R-GGA-983424 Budding of COPII coated vesicle IEA Gallus gallus 1742 R-HSA-1445143 https://reactome.org/PathwayBrowser/#/R-HSA-1445143 RAB8A,10,13,14 hydrolyze GTP IEA Homo sapiens 1742 R-HSA-1458485 https://reactome.org/PathwayBrowser/#/R-HSA-1458485 RALA hydrolyzes GTP IEA Homo sapiens 1742 R-HSA-1675883 https://reactome.org/PathwayBrowser/#/R-HSA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane TAS Homo sapiens 1742 R-HSA-1676152 https://reactome.org/PathwayBrowser/#/R-HSA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane TAS Homo sapiens 1742 R-HSA-2213248 https://reactome.org/PathwayBrowser/#/R-HSA-2213248 Transport of antigen loaded MHC II molecules to surface TAS Homo sapiens 1742 R-HSA-2255342 https://reactome.org/PathwayBrowser/#/R-HSA-2255342 RALA exchanges GDP for GTP IEA Homo sapiens 1742 R-HSA-2255343 https://reactome.org/PathwayBrowser/#/R-HSA-2255343 RAB8A,10,13,14 exchange GDP for GTP IEA Homo sapiens 1742 R-HSA-2316347 https://reactome.org/PathwayBrowser/#/R-HSA-2316347 RAB4A:GTP binds KIF3 and activates KIF3 IEA Homo sapiens 1742 R-HSA-2316349 https://reactome.org/PathwayBrowser/#/R-HSA-2316349 RALA:GTP binds MYO1C:CALM1 and activates MYO1C IEA Homo sapiens 1742 R-HSA-2316352 https://reactome.org/PathwayBrowser/#/R-HSA-2316352 SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane IEA Homo sapiens 1742 R-HSA-432237 https://reactome.org/PathwayBrowser/#/R-HSA-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane TAS Homo sapiens 1742 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 1742 R-HSA-5624127 https://reactome.org/PathwayBrowser/#/R-HSA-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium TAS Homo sapiens 1742 R-HSA-5624130 https://reactome.org/PathwayBrowser/#/R-HSA-5624130 Myristoylated NPHP3 translocates into the ciliary membrane TAS Homo sapiens 1742 R-HSA-5624133 https://reactome.org/PathwayBrowser/#/R-HSA-5624133 ARL3:GTP binds the UNC119B complex TAS Homo sapiens 1742 R-HSA-5624949 https://reactome.org/PathwayBrowser/#/R-HSA-5624949 Assembly of the anterograde IFT train TAS Homo sapiens 1742 R-HSA-5624952 https://reactome.org/PathwayBrowser/#/R-HSA-5624952 Assembly of the retrograde IFT train TAS Homo sapiens 1742 R-HSA-5625416 https://reactome.org/PathwayBrowser/#/R-HSA-5625416 Anterograde IFT TAS Homo sapiens 1742 R-HSA-5625421 https://reactome.org/PathwayBrowser/#/R-HSA-5625421 The anterograde IFT train dissociates TAS Homo sapiens 1742 R-HSA-5625424 https://reactome.org/PathwayBrowser/#/R-HSA-5625424 The retrograde IFT train dissociates TAS Homo sapiens 1742 R-HSA-5625426 https://reactome.org/PathwayBrowser/#/R-HSA-5625426 Retrograde IFT TAS Homo sapiens 1742 R-HSA-5638004 https://reactome.org/PathwayBrowser/#/R-HSA-5638004 RP2 binds ARL3:GTP:UNC119B TAS Homo sapiens 1742 R-HSA-5638006 https://reactome.org/PathwayBrowser/#/R-HSA-5638006 ARL3 hydrolyzes GTP TAS Homo sapiens 1742 R-HSA-5638007 https://reactome.org/PathwayBrowser/#/R-HSA-5638007 RP2 activates the GTPase activity of ARL3 TAS Homo sapiens 1742 R-HSA-8847875 https://reactome.org/PathwayBrowser/#/R-HSA-8847875 ARF1:GTP binds Golgin TRIP11 TAS Homo sapiens 1742 R-HSA-8847880 https://reactome.org/PathwayBrowser/#/R-HSA-8847880 CYTH proteins bind ARF1:GTP TAS Homo sapiens 1742 R-HSA-8847883 https://reactome.org/PathwayBrowser/#/R-HSA-8847883 CYTH proteins stimulate ARF1 GTPase activity TAS Homo sapiens 1742 R-HSA-8854222 https://reactome.org/PathwayBrowser/#/R-HSA-8854222 TBC1D3 associates with RAB5 TAS Homo sapiens 1742 R-HSA-8854255 https://reactome.org/PathwayBrowser/#/R-HSA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 1742 R-HSA-8854329 https://reactome.org/PathwayBrowser/#/R-HSA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 1742 R-HSA-8854604 https://reactome.org/PathwayBrowser/#/R-HSA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A TAS Homo sapiens 1742 R-HSA-8871366 https://reactome.org/PathwayBrowser/#/R-HSA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP TAS Homo sapiens 1742 R-HSA-983422 https://reactome.org/PathwayBrowser/#/R-HSA-983422 Disassembly of COPII coated vesicle TAS Homo sapiens 1742 R-HSA-983424 https://reactome.org/PathwayBrowser/#/R-HSA-983424 Budding of COPII coated vesicle TAS Homo sapiens 1742 R-MMU-1449633 https://reactome.org/PathwayBrowser/#/R-MMU-1449633 Rab8a/10/13/14 Hydrolyze GTP TAS Mus musculus 1742 R-MMU-1458501 https://reactome.org/PathwayBrowser/#/R-MMU-1458501 RalA Hydrolyzes GTP TAS Mus musculus 1742 R-MMU-1675883 https://reactome.org/PathwayBrowser/#/R-MMU-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Mus musculus 1742 R-MMU-1676152 https://reactome.org/PathwayBrowser/#/R-MMU-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Mus musculus 1742 R-MMU-2213248 https://reactome.org/PathwayBrowser/#/R-MMU-2213248 Transport of antigen loaded MHC II molecules to surface IEA Mus musculus 1742 R-MMU-2255339 https://reactome.org/PathwayBrowser/#/R-MMU-2255339 RalA Exchanges GDP for GTP TAS Mus musculus 1742 R-MMU-2255341 https://reactome.org/PathwayBrowser/#/R-MMU-2255341 Rab8A/10/13/14 Exchange GDP for GTP TAS Mus musculus 1742 R-MMU-2316348 https://reactome.org/PathwayBrowser/#/R-MMU-2316348 RalA:GTP binds Myo1c:Calm1 and F-actin TAS Mus musculus 1742 R-MMU-2316350 https://reactome.org/PathwayBrowser/#/R-MMU-2316350 Rab4a:GTP Activates Kif3 TAS Mus musculus 1742 R-MMU-2316351 https://reactome.org/PathwayBrowser/#/R-MMU-2316351 Translocation of Glut4 Vesicle and Docking at the Plasma Membrane TAS Mus musculus 1742 R-MMU-432237 https://reactome.org/PathwayBrowser/#/R-MMU-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Mus musculus 1742 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 1742 R-MMU-5624127 https://reactome.org/PathwayBrowser/#/R-MMU-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Mus musculus 1742 R-MMU-5624130 https://reactome.org/PathwayBrowser/#/R-MMU-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Mus musculus 1742 R-MMU-5624133 https://reactome.org/PathwayBrowser/#/R-MMU-5624133 ARL3:GTP binds the UNC119B complex IEA Mus musculus 1742 R-MMU-5624949 https://reactome.org/PathwayBrowser/#/R-MMU-5624949 Assembly of the anterograde IFT train IEA Mus musculus 1742 R-MMU-5624952 https://reactome.org/PathwayBrowser/#/R-MMU-5624952 Assembly of the retrograde IFT train IEA Mus musculus 1742 R-MMU-5625416 https://reactome.org/PathwayBrowser/#/R-MMU-5625416 Anterograde IFT IEA Mus musculus 1742 R-MMU-5625421 https://reactome.org/PathwayBrowser/#/R-MMU-5625421 The anterograde IFT train dissociates IEA Mus musculus 1742 R-MMU-5625424 https://reactome.org/PathwayBrowser/#/R-MMU-5625424 The retrograde IFT train dissociates IEA Mus musculus 1742 R-MMU-5625426 https://reactome.org/PathwayBrowser/#/R-MMU-5625426 Retrograde IFT IEA Mus musculus 1742 R-MMU-5638004 https://reactome.org/PathwayBrowser/#/R-MMU-5638004 RP2 binds ARL3:GTP:UNC119B IEA Mus musculus 1742 R-MMU-5638006 https://reactome.org/PathwayBrowser/#/R-MMU-5638006 ARL3 hydrolyzes GTP IEA Mus musculus 1742 R-MMU-5638007 https://reactome.org/PathwayBrowser/#/R-MMU-5638007 RP2 activates the GTPase activity of ARL3 IEA Mus musculus 1742 R-MMU-8847875 https://reactome.org/PathwayBrowser/#/R-MMU-8847875 ARF1:GTP binds Golgin TRIP11 IEA Mus musculus 1742 R-MMU-8847880 https://reactome.org/PathwayBrowser/#/R-MMU-8847880 CYTH proteins bind ARF1:GTP IEA Mus musculus 1742 R-MMU-8847883 https://reactome.org/PathwayBrowser/#/R-MMU-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Mus musculus 1742 R-MMU-8854255 https://reactome.org/PathwayBrowser/#/R-MMU-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Mus musculus 1742 R-MMU-8854329 https://reactome.org/PathwayBrowser/#/R-MMU-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Mus musculus 1742 R-MMU-8854604 https://reactome.org/PathwayBrowser/#/R-MMU-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Mus musculus 1742 R-MMU-8871366 https://reactome.org/PathwayBrowser/#/R-MMU-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Mus musculus 1742 R-MMU-983422 https://reactome.org/PathwayBrowser/#/R-MMU-983422 Disassembly of COPII coated vesicle IEA Mus musculus 1742 R-MMU-983424 https://reactome.org/PathwayBrowser/#/R-MMU-983424 Budding of COPII coated vesicle IEA Mus musculus 1742 R-PFA-1675883 https://reactome.org/PathwayBrowser/#/R-PFA-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Plasmodium falciparum 1742 R-PFA-1676152 https://reactome.org/PathwayBrowser/#/R-PFA-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Plasmodium falciparum 1742 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 1742 R-PFA-8854255 https://reactome.org/PathwayBrowser/#/R-PFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 1742 R-PFA-8854329 https://reactome.org/PathwayBrowser/#/R-PFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 1742 R-RNO-1675883 https://reactome.org/PathwayBrowser/#/R-RNO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Rattus norvegicus 1742 R-RNO-1676152 https://reactome.org/PathwayBrowser/#/R-RNO-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Rattus norvegicus 1742 R-RNO-2213248 https://reactome.org/PathwayBrowser/#/R-RNO-2213248 Transport of antigen loaded MHC II molecules to surface IEA Rattus norvegicus 1742 R-RNO-2457808 https://reactome.org/PathwayBrowser/#/R-RNO-2457808 Rab8A/13/14 Exchange GDP for GTP TAS Rattus norvegicus 1742 R-RNO-432237 https://reactome.org/PathwayBrowser/#/R-RNO-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Rattus norvegicus 1742 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 1742 R-RNO-5624127 https://reactome.org/PathwayBrowser/#/R-RNO-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Rattus norvegicus 1742 R-RNO-5624130 https://reactome.org/PathwayBrowser/#/R-RNO-5624130 Myristoylated NPHP3 translocates into the ciliary membrane IEA Rattus norvegicus 1742 R-RNO-5624133 https://reactome.org/PathwayBrowser/#/R-RNO-5624133 ARL3:GTP binds the UNC119B complex IEA Rattus norvegicus 1742 R-RNO-5624949 https://reactome.org/PathwayBrowser/#/R-RNO-5624949 Assembly of the anterograde IFT train IEA Rattus norvegicus 1742 R-RNO-5624952 https://reactome.org/PathwayBrowser/#/R-RNO-5624952 Assembly of the retrograde IFT train IEA Rattus norvegicus 1742 R-RNO-5625416 https://reactome.org/PathwayBrowser/#/R-RNO-5625416 Anterograde IFT IEA Rattus norvegicus 1742 R-RNO-5625421 https://reactome.org/PathwayBrowser/#/R-RNO-5625421 The anterograde IFT train dissociates IEA Rattus norvegicus 1742 R-RNO-5625424 https://reactome.org/PathwayBrowser/#/R-RNO-5625424 The retrograde IFT train dissociates IEA Rattus norvegicus 1742 R-RNO-5625426 https://reactome.org/PathwayBrowser/#/R-RNO-5625426 Retrograde IFT IEA Rattus norvegicus 1742 R-RNO-5638004 https://reactome.org/PathwayBrowser/#/R-RNO-5638004 RP2 binds ARL3:GTP:UNC119B IEA Rattus norvegicus 1742 R-RNO-5638006 https://reactome.org/PathwayBrowser/#/R-RNO-5638006 ARL3 hydrolyzes GTP IEA Rattus norvegicus 1742 R-RNO-5638007 https://reactome.org/PathwayBrowser/#/R-RNO-5638007 RP2 activates the GTPase activity of ARL3 IEA Rattus norvegicus 1742 R-RNO-8847875 https://reactome.org/PathwayBrowser/#/R-RNO-8847875 ARF1:GTP binds Golgin TRIP11 IEA Rattus norvegicus 1742 R-RNO-8847880 https://reactome.org/PathwayBrowser/#/R-RNO-8847880 CYTH proteins bind ARF1:GTP IEA Rattus norvegicus 1742 R-RNO-8847883 https://reactome.org/PathwayBrowser/#/R-RNO-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Rattus norvegicus 1742 R-RNO-8854255 https://reactome.org/PathwayBrowser/#/R-RNO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 1742 R-RNO-8854329 https://reactome.org/PathwayBrowser/#/R-RNO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 1742 R-RNO-8854604 https://reactome.org/PathwayBrowser/#/R-RNO-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Rattus norvegicus 1742 R-RNO-8871366 https://reactome.org/PathwayBrowser/#/R-RNO-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP IEA Rattus norvegicus 1742 R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus 1742 R-RNO-983424 https://reactome.org/PathwayBrowser/#/R-RNO-983424 Budding of COPII coated vesicle IEA Rattus norvegicus 1742 R-SCE-1675883 https://reactome.org/PathwayBrowser/#/R-SCE-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Saccharomyces cerevisiae 1742 R-SCE-1676152 https://reactome.org/PathwayBrowser/#/R-SCE-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Saccharomyces cerevisiae 1742 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 1742 R-SCE-8847880 https://reactome.org/PathwayBrowser/#/R-SCE-8847880 CYTH proteins bind ARF1:GTP IEA Saccharomyces cerevisiae 1742 R-SCE-8847883 https://reactome.org/PathwayBrowser/#/R-SCE-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Saccharomyces cerevisiae 1742 R-SCE-8854255 https://reactome.org/PathwayBrowser/#/R-SCE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 1742 R-SCE-8854329 https://reactome.org/PathwayBrowser/#/R-SCE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 1742 R-SPO-1675883 https://reactome.org/PathwayBrowser/#/R-SPO-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Schizosaccharomyces pombe 1742 R-SPO-1676152 https://reactome.org/PathwayBrowser/#/R-SPO-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Schizosaccharomyces pombe 1742 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 1742 R-SPO-8847880 https://reactome.org/PathwayBrowser/#/R-SPO-8847880 CYTH proteins bind ARF1:GTP IEA Schizosaccharomyces pombe 1742 R-SPO-8847883 https://reactome.org/PathwayBrowser/#/R-SPO-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Schizosaccharomyces pombe 1742 R-SPO-8854255 https://reactome.org/PathwayBrowser/#/R-SPO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 1742 R-SPO-8854329 https://reactome.org/PathwayBrowser/#/R-SPO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 1742 R-SSC-1675883 https://reactome.org/PathwayBrowser/#/R-SSC-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Sus scrofa 1742 R-SSC-1676152 https://reactome.org/PathwayBrowser/#/R-SSC-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Sus scrofa 1742 R-SSC-2213248 https://reactome.org/PathwayBrowser/#/R-SSC-2213248 Transport of antigen loaded MHC II molecules to surface IEA Sus scrofa 1742 R-SSC-432237 https://reactome.org/PathwayBrowser/#/R-SSC-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Sus scrofa 1742 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 1742 R-SSC-5624127 https://reactome.org/PathwayBrowser/#/R-SSC-5624127 ARL6:GTP and the BBSome target cargo to the primary cilium IEA Sus scrofa 1742 R-SSC-5624949 https://reactome.org/PathwayBrowser/#/R-SSC-5624949 Assembly of the anterograde IFT train IEA Sus scrofa 1742 R-SSC-5624952 https://reactome.org/PathwayBrowser/#/R-SSC-5624952 Assembly of the retrograde IFT train IEA Sus scrofa 1742 R-SSC-5625416 https://reactome.org/PathwayBrowser/#/R-SSC-5625416 Anterograde IFT IEA Sus scrofa 1742 R-SSC-5625421 https://reactome.org/PathwayBrowser/#/R-SSC-5625421 The anterograde IFT train dissociates IEA Sus scrofa 1742 R-SSC-5625424 https://reactome.org/PathwayBrowser/#/R-SSC-5625424 The retrograde IFT train dissociates IEA Sus scrofa 1742 R-SSC-5625426 https://reactome.org/PathwayBrowser/#/R-SSC-5625426 Retrograde IFT IEA Sus scrofa 1742 R-SSC-8847875 https://reactome.org/PathwayBrowser/#/R-SSC-8847875 ARF1:GTP binds Golgin TRIP11 IEA Sus scrofa 1742 R-SSC-8847880 https://reactome.org/PathwayBrowser/#/R-SSC-8847880 CYTH proteins bind ARF1:GTP IEA Sus scrofa 1742 R-SSC-8847883 https://reactome.org/PathwayBrowser/#/R-SSC-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Sus scrofa 1742 R-SSC-8854222 https://reactome.org/PathwayBrowser/#/R-SSC-8854222 TBC1D3 associates with RAB5 IEA Sus scrofa 1742 R-SSC-8854255 https://reactome.org/PathwayBrowser/#/R-SSC-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 1742 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 1742 R-SSC-8854604 https://reactome.org/PathwayBrowser/#/R-SSC-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Sus scrofa 1742 R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa 1742 R-SSC-983424 https://reactome.org/PathwayBrowser/#/R-SSC-983424 Budding of COPII coated vesicle IEA Sus scrofa 1742 R-XTR-1675883 https://reactome.org/PathwayBrowser/#/R-XTR-1675883 PI is phosphorylated to PI4P by PI4KB at the Golgi membrane IEA Xenopus tropicalis 1742 R-XTR-1676152 https://reactome.org/PathwayBrowser/#/R-XTR-1676152 PI4KB binds to ARF1/3:GTP at the Golgi membrane IEA Xenopus tropicalis 1742 R-XTR-432237 https://reactome.org/PathwayBrowser/#/R-XTR-432237 Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane IEA Xenopus tropicalis 1742 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 1742 R-XTR-8847875 https://reactome.org/PathwayBrowser/#/R-XTR-8847875 ARF1:GTP binds Golgin TRIP11 IEA Xenopus tropicalis 1742 R-XTR-8847880 https://reactome.org/PathwayBrowser/#/R-XTR-8847880 CYTH proteins bind ARF1:GTP IEA Xenopus tropicalis 1742 R-XTR-8847883 https://reactome.org/PathwayBrowser/#/R-XTR-8847883 CYTH proteins stimulate ARF1 GTPase activity IEA Xenopus tropicalis 1742 R-XTR-8854255 https://reactome.org/PathwayBrowser/#/R-XTR-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 1742 R-XTR-8854329 https://reactome.org/PathwayBrowser/#/R-XTR-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 1742 R-XTR-983424 https://reactome.org/PathwayBrowser/#/R-XTR-983424 Budding of COPII coated vesicle IEA Xenopus tropicalis 1749 R-HSA-9683648 https://reactome.org/PathwayBrowser/#/R-HSA-9683648 Spike trimer glycoside chains are extended TAS Homo sapiens 1749 R-HSA-9683760 https://reactome.org/PathwayBrowser/#/R-HSA-9683760 GalNAc is transferred onto 3a TAS Homo sapiens 1749 R-HSA-9694438 https://reactome.org/PathwayBrowser/#/R-HSA-9694438 GalNAc is transferred onto 3a IEA Homo sapiens 1765 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 1765 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 1765 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 1765 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 1765 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 1765 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 1765 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 1765 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 1765 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 1765 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 1765 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 1765 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 1765 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 1765 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 1765 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 1765 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 1771 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 1771 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 1771 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 1771 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 1771 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 1771 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 1771 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 1771 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 1771 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 1771 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 1771 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 1771 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 1771 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 1771 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 1771 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 1771 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 1772 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 1772 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 1772 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 1772 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 1772 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 1772 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 1772 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 1772 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 1772 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 1772 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 1772 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 1772 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 1772 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 1772 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 1772 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 1772 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 1776 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 1776 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 1776 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 1776 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 1776 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 1776 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 1776 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 1776 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 1776 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 1776 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 1776 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 1776 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 1776 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 1776 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 1776 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 1776 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 1882 R-BTA-879528 https://reactome.org/PathwayBrowser/#/R-BTA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Bos taurus 1882 R-BTA-879584 https://reactome.org/PathwayBrowser/#/R-BTA-879584 SLCO3A1 isoform 1 has a broad substrate specificity IEA Bos taurus 1882 R-CEL-879528 https://reactome.org/PathwayBrowser/#/R-CEL-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Caenorhabditis elegans 1882 R-CFA-879528 https://reactome.org/PathwayBrowser/#/R-CFA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Canis familiaris 1882 R-CFA-879584 https://reactome.org/PathwayBrowser/#/R-CFA-879584 SLCO3A1 isoform 1 has a broad substrate specificity IEA Canis familiaris 1882 R-DME-879528 https://reactome.org/PathwayBrowser/#/R-DME-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Drosophila melanogaster 1882 R-GGA-879528 https://reactome.org/PathwayBrowser/#/R-GGA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Gallus gallus 1882 R-GGA-879584 https://reactome.org/PathwayBrowser/#/R-GGA-879584 SLCO3A1 isoform 1 has a broad substrate specificity IEA Gallus gallus 1882 R-HSA-5661188 https://reactome.org/PathwayBrowser/#/R-HSA-5661188 Defective SLCO2A1 does not transport PGT substrates from extracellular region to cytosol TAS Homo sapiens 1882 R-HSA-879528 https://reactome.org/PathwayBrowser/#/R-HSA-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol TAS Homo sapiens 1882 R-HSA-879584 https://reactome.org/PathwayBrowser/#/R-HSA-879584 SLCO3A1 isoform 1 has a broad substrate specificity TAS Homo sapiens 1882 R-MMU-879528 https://reactome.org/PathwayBrowser/#/R-MMU-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Mus musculus 1882 R-MMU-879584 https://reactome.org/PathwayBrowser/#/R-MMU-879584 SLCO3A1 isoform 1 has a broad substrate specificity IEA Mus musculus 1882 R-RNO-879528 https://reactome.org/PathwayBrowser/#/R-RNO-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Rattus norvegicus 1882 R-RNO-879584 https://reactome.org/PathwayBrowser/#/R-RNO-879584 SLCO3A1 isoform 1 has a broad substrate specificity IEA Rattus norvegicus 1882 R-SSC-879528 https://reactome.org/PathwayBrowser/#/R-SSC-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Sus scrofa 1882 R-SSC-879584 https://reactome.org/PathwayBrowser/#/R-SSC-879584 SLCO3A1 isoform 1 has a broad substrate specificity IEA Sus scrofa 1882 R-XTR-879528 https://reactome.org/PathwayBrowser/#/R-XTR-879528 SLCO2A1 transports PGT substrates from extracellular region to cytosol IEA Xenopus tropicalis 1895 R-BTA-9726949 https://reactome.org/PathwayBrowser/#/R-BTA-9726949 PTGIR binds PTGIR agonists IEA Bos taurus 1895 R-CFA-9726949 https://reactome.org/PathwayBrowser/#/R-CFA-9726949 PTGIR binds PTGIR agonists IEA Canis familiaris 1895 R-DME-9726949 https://reactome.org/PathwayBrowser/#/R-DME-9726949 PTGIR binds PTGIR agonists IEA Drosophila melanogaster 1895 R-DRE-9726949 https://reactome.org/PathwayBrowser/#/R-DRE-9726949 PTGIR binds PTGIR agonists IEA Danio rerio 1895 R-HSA-9726949 https://reactome.org/PathwayBrowser/#/R-HSA-9726949 PTGIR binds PTGIR agonists TAS Homo sapiens 1895 R-MMU-9726949 https://reactome.org/PathwayBrowser/#/R-MMU-9726949 PTGIR binds PTGIR agonists IEA Mus musculus 1895 R-RNO-9726949 https://reactome.org/PathwayBrowser/#/R-RNO-9726949 PTGIR binds PTGIR agonists IEA Rattus norvegicus 1895 R-SSC-9726949 https://reactome.org/PathwayBrowser/#/R-SSC-9726949 PTGIR binds PTGIR agonists IEA Sus scrofa 1895 R-XTR-9726949 https://reactome.org/PathwayBrowser/#/R-XTR-9726949 PTGIR binds PTGIR agonists IEA Xenopus tropicalis 1909 R-BTA-9677320 https://reactome.org/PathwayBrowser/#/R-BTA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Bos taurus 1909 R-CFA-9677320 https://reactome.org/PathwayBrowser/#/R-CFA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Canis familiaris 1909 R-DRE-9677320 https://reactome.org/PathwayBrowser/#/R-DRE-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Danio rerio 1909 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus 1909 R-HSA-9677320 https://reactome.org/PathwayBrowser/#/R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors TAS Homo sapiens 1909 R-MMU-9677320 https://reactome.org/PathwayBrowser/#/R-MMU-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Mus musculus 1909 R-RNO-9677320 https://reactome.org/PathwayBrowser/#/R-RNO-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Rattus norvegicus 1909 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa 1909 R-XTR-9677320 https://reactome.org/PathwayBrowser/#/R-XTR-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Xenopus tropicalis 1940 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 1940 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 1940 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 1940 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 1940 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 1940 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 1940 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 1940 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 1940 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 1940 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 1959 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 1959 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 1959 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 1959 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 1959 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 1959 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 1959 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 1959 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 1959 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 1959 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 1960 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 1960 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 1960 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 1960 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 1960 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 1960 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 1960 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 1960 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 1960 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 1960 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 200 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 200 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 200 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 200 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 200 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 200 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 200 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 200 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 200 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 200 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 200 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 200 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 200 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 200 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 200 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 200 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 200 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 200 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 200 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 200 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 200 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 200 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 200 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 200 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 200 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 200 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 200 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 200 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 200 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 200 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 200 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 201 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 201 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 201 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 201 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 201 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 201 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 201 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 201 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 201 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 201 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 201 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 201 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 202 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 202 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 202 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 202 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 202 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 202 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 202 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 202 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 202 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 202 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 202 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 202 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 203 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 203 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 203 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 203 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 203 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 203 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 203 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 203 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 203 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 203 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 203 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 203 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 204 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 204 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 204 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 204 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 204 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 204 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 204 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 204 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 204 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 204 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 204 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 204 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 204 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 204 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 204 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 204 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 204 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 204 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 205 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 205 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 205 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 205 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 205 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 205 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 205 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 205 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 205 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 205 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 205 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 205 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 205 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 205 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 205 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 205 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 205 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 205 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 207 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 207 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 207 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 207 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 207 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 207 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 207 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 207 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 209 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 209 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 209 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 209 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 209 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 209 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 209 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 209 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 209 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 209 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 209 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 209 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 209 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 209 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 209 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 209 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 209 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 209 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 212 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 212 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 212 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 212 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 212 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 212 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 212 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 212 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 214 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 214 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 214 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 214 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 214 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 214 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 214 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 214 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 214 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 214 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 214 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 214 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 214 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 214 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 214 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 214 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 214 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 214 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 2144 R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 2144 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 2144 R-BTA-391211 https://reactome.org/PathwayBrowser/#/R-BTA-391211 Trace amine-associated receptors can bind trace amines IEA Bos taurus 2144 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 2144 R-CEL-391211 https://reactome.org/PathwayBrowser/#/R-CEL-391211 Trace amine-associated receptors can bind trace amines IEA Caenorhabditis elegans 2144 R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 2144 R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 2144 R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 2144 R-DRE-391211 https://reactome.org/PathwayBrowser/#/R-DRE-391211 Trace amine-associated receptors can bind trace amines IEA Danio rerio 2144 R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 2144 R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 2144 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 2144 R-HSA-391211 https://reactome.org/PathwayBrowser/#/R-HSA-391211 Trace amine-associated receptors can bind trace amines TAS Homo sapiens 2144 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 2144 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 2144 R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 2144 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 2144 R-MMU-391211 https://reactome.org/PathwayBrowser/#/R-MMU-391211 Trace amine-associated receptors can bind trace amines IEA Mus musculus 2144 R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 2144 R-RNO-391211 https://reactome.org/PathwayBrowser/#/R-RNO-391211 Trace amine-associated receptors can bind trace amines IEA Rattus norvegicus 2144 R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 2144 R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 2144 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 2144 R-XTR-391211 https://reactome.org/PathwayBrowser/#/R-XTR-391211 Trace amine-associated receptors can bind trace amines IEA Xenopus tropicalis 2147 R-BTA-9714580 https://reactome.org/PathwayBrowser/#/R-BTA-9714580 SLC6A3 binds DRIs IEA Bos taurus 2147 R-CEL-9714580 https://reactome.org/PathwayBrowser/#/R-CEL-9714580 SLC6A3 binds DRIs IEA Caenorhabditis elegans 2147 R-CFA-9714580 https://reactome.org/PathwayBrowser/#/R-CFA-9714580 SLC6A3 binds DRIs IEA Canis familiaris 2147 R-DME-9714580 https://reactome.org/PathwayBrowser/#/R-DME-9714580 SLC6A3 binds DRIs IEA Drosophila melanogaster 2147 R-DRE-9714580 https://reactome.org/PathwayBrowser/#/R-DRE-9714580 SLC6A3 binds DRIs IEA Danio rerio 2147 R-HSA-9714580 https://reactome.org/PathwayBrowser/#/R-HSA-9714580 SLC6A3 binds DRIs TAS Homo sapiens 2147 R-MMU-9714580 https://reactome.org/PathwayBrowser/#/R-MMU-9714580 SLC6A3 binds DRIs IEA Mus musculus 2147 R-PFA-9714580 https://reactome.org/PathwayBrowser/#/R-PFA-9714580 SLC6A3 binds DRIs IEA Plasmodium falciparum 2147 R-RNO-9714580 https://reactome.org/PathwayBrowser/#/R-RNO-9714580 SLC6A3 binds DRIs IEA Rattus norvegicus 2147 R-SSC-9714580 https://reactome.org/PathwayBrowser/#/R-SSC-9714580 SLC6A3 binds DRIs IEA Sus scrofa 2147 R-XTR-9714580 https://reactome.org/PathwayBrowser/#/R-XTR-9714580 SLC6A3 binds DRIs IEA Xenopus tropicalis 2150 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 2150 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 2150 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 2150 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 2150 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 2150 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 2150 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 2150 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 2150 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 2150 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 2150 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 2150 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 2150 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 2150 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 2150 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 2150 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 2182 R-BTA-9667456 https://reactome.org/PathwayBrowser/#/R-BTA-9667456 AVPR1A,B bind desmopressin IEA Bos taurus 2182 R-BTA-9667563 https://reactome.org/PathwayBrowser/#/R-BTA-9667563 AVPR2 bind desmopressin IEA Bos taurus 2182 R-CFA-9667456 https://reactome.org/PathwayBrowser/#/R-CFA-9667456 AVPR1A,B bind desmopressin IEA Canis familiaris 2182 R-CFA-9667563 https://reactome.org/PathwayBrowser/#/R-CFA-9667563 AVPR2 bind desmopressin IEA Canis familiaris 2182 R-DRE-9667456 https://reactome.org/PathwayBrowser/#/R-DRE-9667456 AVPR1A,B bind desmopressin IEA Danio rerio 2182 R-DRE-9667563 https://reactome.org/PathwayBrowser/#/R-DRE-9667563 AVPR2 bind desmopressin IEA Danio rerio 2182 R-GGA-9667456 https://reactome.org/PathwayBrowser/#/R-GGA-9667456 AVPR1A,B bind desmopressin IEA Gallus gallus 2182 R-HSA-9667456 https://reactome.org/PathwayBrowser/#/R-HSA-9667456 AVPR1A,B bind desmopressin TAS Homo sapiens 2182 R-HSA-9667563 https://reactome.org/PathwayBrowser/#/R-HSA-9667563 AVPR2 bind desmopressin TAS Homo sapiens 2182 R-MMU-9667456 https://reactome.org/PathwayBrowser/#/R-MMU-9667456 AVPR1A,B bind desmopressin IEA Mus musculus 2182 R-MMU-9667563 https://reactome.org/PathwayBrowser/#/R-MMU-9667563 AVPR2 bind desmopressin IEA Mus musculus 2182 R-RNO-9667456 https://reactome.org/PathwayBrowser/#/R-RNO-9667456 AVPR1A,B bind desmopressin IEA Rattus norvegicus 2182 R-RNO-9667563 https://reactome.org/PathwayBrowser/#/R-RNO-9667563 AVPR2 bind desmopressin IEA Rattus norvegicus 2182 R-SSC-9667456 https://reactome.org/PathwayBrowser/#/R-SSC-9667456 AVPR1A,B bind desmopressin IEA Sus scrofa 2182 R-SSC-9667563 https://reactome.org/PathwayBrowser/#/R-SSC-9667563 AVPR2 bind desmopressin IEA Sus scrofa 2182 R-XTR-9667456 https://reactome.org/PathwayBrowser/#/R-XTR-9667456 AVPR1A,B bind desmopressin IEA Xenopus tropicalis 2182 R-XTR-9667563 https://reactome.org/PathwayBrowser/#/R-XTR-9667563 AVPR2 bind desmopressin IEA Xenopus tropicalis 2197 R-BTA-9667569 https://reactome.org/PathwayBrowser/#/R-BTA-9667569 AVPR1A,2 bind AVPR antagonists IEA Bos taurus 2197 R-CFA-9667569 https://reactome.org/PathwayBrowser/#/R-CFA-9667569 AVPR1A,2 bind AVPR antagonists IEA Canis familiaris 2197 R-DRE-9667569 https://reactome.org/PathwayBrowser/#/R-DRE-9667569 AVPR1A,2 bind AVPR antagonists IEA Danio rerio 2197 R-GGA-9667569 https://reactome.org/PathwayBrowser/#/R-GGA-9667569 AVPR1A,2 bind AVPR antagonists IEA Gallus gallus 2197 R-HSA-9667569 https://reactome.org/PathwayBrowser/#/R-HSA-9667569 AVPR1A,2 bind AVPR antagonists TAS Homo sapiens 2197 R-MMU-9667569 https://reactome.org/PathwayBrowser/#/R-MMU-9667569 AVPR1A,2 bind AVPR antagonists IEA Mus musculus 2197 R-RNO-9667569 https://reactome.org/PathwayBrowser/#/R-RNO-9667569 AVPR1A,2 bind AVPR antagonists IEA Rattus norvegicus 2197 R-SSC-9667569 https://reactome.org/PathwayBrowser/#/R-SSC-9667569 AVPR1A,2 bind AVPR antagonists IEA Sus scrofa 2197 R-XTR-9667569 https://reactome.org/PathwayBrowser/#/R-XTR-9667569 AVPR1A,2 bind AVPR antagonists IEA Xenopus tropicalis 2199 R-BTA-9667569 https://reactome.org/PathwayBrowser/#/R-BTA-9667569 AVPR1A,2 bind AVPR antagonists IEA Bos taurus 2199 R-CFA-9667569 https://reactome.org/PathwayBrowser/#/R-CFA-9667569 AVPR1A,2 bind AVPR antagonists IEA Canis familiaris 2199 R-DRE-9667569 https://reactome.org/PathwayBrowser/#/R-DRE-9667569 AVPR1A,2 bind AVPR antagonists IEA Danio rerio 2199 R-GGA-9667569 https://reactome.org/PathwayBrowser/#/R-GGA-9667569 AVPR1A,2 bind AVPR antagonists IEA Gallus gallus 2199 R-HSA-9667569 https://reactome.org/PathwayBrowser/#/R-HSA-9667569 AVPR1A,2 bind AVPR antagonists TAS Homo sapiens 2199 R-MMU-9667569 https://reactome.org/PathwayBrowser/#/R-MMU-9667569 AVPR1A,2 bind AVPR antagonists IEA Mus musculus 2199 R-RNO-9667569 https://reactome.org/PathwayBrowser/#/R-RNO-9667569 AVPR1A,2 bind AVPR antagonists IEA Rattus norvegicus 2199 R-SSC-9667569 https://reactome.org/PathwayBrowser/#/R-SSC-9667569 AVPR1A,2 bind AVPR antagonists IEA Sus scrofa 2199 R-XTR-9667569 https://reactome.org/PathwayBrowser/#/R-XTR-9667569 AVPR1A,2 bind AVPR antagonists IEA Xenopus tropicalis 22 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 22 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 22 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 22 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 22 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 22 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 22 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 22 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 22 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 22 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 22 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 22 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 22 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 22 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 22 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 22 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 22 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 22 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 22 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 22 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 22 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 22 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 22 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 22 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 22 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 22 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 22 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 22 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 2203 R-BTA-9667569 https://reactome.org/PathwayBrowser/#/R-BTA-9667569 AVPR1A,2 bind AVPR antagonists IEA Bos taurus 2203 R-CFA-9667569 https://reactome.org/PathwayBrowser/#/R-CFA-9667569 AVPR1A,2 bind AVPR antagonists IEA Canis familiaris 2203 R-DRE-9667569 https://reactome.org/PathwayBrowser/#/R-DRE-9667569 AVPR1A,2 bind AVPR antagonists IEA Danio rerio 2203 R-GGA-9667569 https://reactome.org/PathwayBrowser/#/R-GGA-9667569 AVPR1A,2 bind AVPR antagonists IEA Gallus gallus 2203 R-HSA-9667569 https://reactome.org/PathwayBrowser/#/R-HSA-9667569 AVPR1A,2 bind AVPR antagonists TAS Homo sapiens 2203 R-MMU-9667569 https://reactome.org/PathwayBrowser/#/R-MMU-9667569 AVPR1A,2 bind AVPR antagonists IEA Mus musculus 2203 R-RNO-9667569 https://reactome.org/PathwayBrowser/#/R-RNO-9667569 AVPR1A,2 bind AVPR antagonists IEA Rattus norvegicus 2203 R-SSC-9667569 https://reactome.org/PathwayBrowser/#/R-SSC-9667569 AVPR1A,2 bind AVPR antagonists IEA Sus scrofa 2203 R-XTR-9667569 https://reactome.org/PathwayBrowser/#/R-XTR-9667569 AVPR1A,2 bind AVPR antagonists IEA Xenopus tropicalis 2213 R-BTA-9667619 https://reactome.org/PathwayBrowser/#/R-BTA-9667619 AVPR1A,B,2 bind atosiban IEA Bos taurus 2213 R-CFA-9667619 https://reactome.org/PathwayBrowser/#/R-CFA-9667619 AVPR1A,B,2 bind atosiban IEA Canis familiaris 2213 R-DRE-9667619 https://reactome.org/PathwayBrowser/#/R-DRE-9667619 AVPR1A,B,2 bind atosiban IEA Danio rerio 2213 R-GGA-9667619 https://reactome.org/PathwayBrowser/#/R-GGA-9667619 AVPR1A,B,2 bind atosiban IEA Gallus gallus 2213 R-HSA-9667619 https://reactome.org/PathwayBrowser/#/R-HSA-9667619 AVPR1A,B,2 bind atosiban TAS Homo sapiens 2213 R-MMU-9667619 https://reactome.org/PathwayBrowser/#/R-MMU-9667619 AVPR1A,B,2 bind atosiban IEA Mus musculus 2213 R-RNO-9667619 https://reactome.org/PathwayBrowser/#/R-RNO-9667619 AVPR1A,B,2 bind atosiban IEA Rattus norvegicus 2213 R-SSC-9667619 https://reactome.org/PathwayBrowser/#/R-SSC-9667619 AVPR1A,B,2 bind atosiban IEA Sus scrofa 2213 R-XTR-9667619 https://reactome.org/PathwayBrowser/#/R-XTR-9667619 AVPR1A,B,2 bind atosiban IEA Xenopus tropicalis 2226 R-BTA-9667569 https://reactome.org/PathwayBrowser/#/R-BTA-9667569 AVPR1A,2 bind AVPR antagonists IEA Bos taurus 2226 R-CFA-9667569 https://reactome.org/PathwayBrowser/#/R-CFA-9667569 AVPR1A,2 bind AVPR antagonists IEA Canis familiaris 2226 R-DRE-9667569 https://reactome.org/PathwayBrowser/#/R-DRE-9667569 AVPR1A,2 bind AVPR antagonists IEA Danio rerio 2226 R-GGA-9667569 https://reactome.org/PathwayBrowser/#/R-GGA-9667569 AVPR1A,2 bind AVPR antagonists IEA Gallus gallus 2226 R-HSA-9667569 https://reactome.org/PathwayBrowser/#/R-HSA-9667569 AVPR1A,2 bind AVPR antagonists TAS Homo sapiens 2226 R-MMU-9667569 https://reactome.org/PathwayBrowser/#/R-MMU-9667569 AVPR1A,2 bind AVPR antagonists IEA Mus musculus 2226 R-RNO-9667569 https://reactome.org/PathwayBrowser/#/R-RNO-9667569 AVPR1A,2 bind AVPR antagonists IEA Rattus norvegicus 2226 R-SSC-9667569 https://reactome.org/PathwayBrowser/#/R-SSC-9667569 AVPR1A,2 bind AVPR antagonists IEA Sus scrofa 2226 R-XTR-9667569 https://reactome.org/PathwayBrowser/#/R-XTR-9667569 AVPR1A,2 bind AVPR antagonists IEA Xenopus tropicalis 2238 R-BTA-9667569 https://reactome.org/PathwayBrowser/#/R-BTA-9667569 AVPR1A,2 bind AVPR antagonists IEA Bos taurus 2238 R-CFA-9667569 https://reactome.org/PathwayBrowser/#/R-CFA-9667569 AVPR1A,2 bind AVPR antagonists IEA Canis familiaris 2238 R-DRE-9667569 https://reactome.org/PathwayBrowser/#/R-DRE-9667569 AVPR1A,2 bind AVPR antagonists IEA Danio rerio 2238 R-GGA-9667569 https://reactome.org/PathwayBrowser/#/R-GGA-9667569 AVPR1A,2 bind AVPR antagonists IEA Gallus gallus 2238 R-HSA-9667569 https://reactome.org/PathwayBrowser/#/R-HSA-9667569 AVPR1A,2 bind AVPR antagonists TAS Homo sapiens 2238 R-MMU-9667569 https://reactome.org/PathwayBrowser/#/R-MMU-9667569 AVPR1A,2 bind AVPR antagonists IEA Mus musculus 2238 R-RNO-9667569 https://reactome.org/PathwayBrowser/#/R-RNO-9667569 AVPR1A,2 bind AVPR antagonists IEA Rattus norvegicus 2238 R-SSC-9667569 https://reactome.org/PathwayBrowser/#/R-SSC-9667569 AVPR1A,2 bind AVPR antagonists IEA Sus scrofa 2238 R-XTR-9667569 https://reactome.org/PathwayBrowser/#/R-XTR-9667569 AVPR1A,2 bind AVPR antagonists IEA Xenopus tropicalis 224 R-BTA-209821 https://reactome.org/PathwayBrowser/#/R-BTA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Bos taurus 224 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 224 R-BTA-419334 https://reactome.org/PathwayBrowser/#/R-BTA-419334 Melatonin receptors can bind melatonin IEA Bos taurus 224 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 224 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 224 R-BTA-8936519 https://reactome.org/PathwayBrowser/#/R-BTA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Bos taurus 224 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 224 R-CEL-419334 https://reactome.org/PathwayBrowser/#/R-CEL-419334 Melatonin receptors can bind melatonin IEA Caenorhabditis elegans 224 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 224 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 224 R-CFA-209821 https://reactome.org/PathwayBrowser/#/R-CFA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Canis familiaris 224 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 224 R-CFA-419334 https://reactome.org/PathwayBrowser/#/R-CFA-419334 Melatonin receptors can bind melatonin IEA Canis familiaris 224 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 224 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 224 R-CFA-8936519 https://reactome.org/PathwayBrowser/#/R-CFA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Canis familiaris 224 R-DDI-209821 https://reactome.org/PathwayBrowser/#/R-DDI-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Dictyostelium discoideum 224 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 224 R-DME-419334 https://reactome.org/PathwayBrowser/#/R-DME-419334 Melatonin receptors can bind melatonin IEA Drosophila melanogaster 224 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 224 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 224 R-DRE-209821 https://reactome.org/PathwayBrowser/#/R-DRE-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Danio rerio 224 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 224 R-DRE-419334 https://reactome.org/PathwayBrowser/#/R-DRE-419334 Melatonin receptors can bind melatonin IEA Danio rerio 224 R-GGA-209821 https://reactome.org/PathwayBrowser/#/R-GGA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Gallus gallus 224 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 224 R-GGA-419334 https://reactome.org/PathwayBrowser/#/R-GGA-419334 Melatonin receptors can bind melatonin IEA Gallus gallus 224 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 224 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 224 R-GGA-8936519 https://reactome.org/PathwayBrowser/#/R-GGA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Gallus gallus 224 R-HSA-209821 https://reactome.org/PathwayBrowser/#/R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin TAS Homo sapiens 224 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 224 R-HSA-419334 https://reactome.org/PathwayBrowser/#/R-HSA-419334 Melatonin receptors can bind melatonin TAS Homo sapiens 224 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 224 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 224 R-HSA-8936519 https://reactome.org/PathwayBrowser/#/R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones TAS Homo sapiens 224 R-MMU-209821 https://reactome.org/PathwayBrowser/#/R-MMU-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Mus musculus 224 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 224 R-MMU-419334 https://reactome.org/PathwayBrowser/#/R-MMU-419334 Melatonin receptors can bind melatonin IEA Mus musculus 224 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 224 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 224 R-MMU-8936519 https://reactome.org/PathwayBrowser/#/R-MMU-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Mus musculus 224 R-RNO-209821 https://reactome.org/PathwayBrowser/#/R-RNO-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Rattus norvegicus 224 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 224 R-RNO-419334 https://reactome.org/PathwayBrowser/#/R-RNO-419334 Melatonin receptors can bind melatonin IEA Rattus norvegicus 224 R-RNO-8936519 https://reactome.org/PathwayBrowser/#/R-RNO-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Rattus norvegicus 224 R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa 224 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 224 R-SSC-419334 https://reactome.org/PathwayBrowser/#/R-SSC-419334 Melatonin receptors can bind melatonin IEA Sus scrofa 224 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 224 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 224 R-SSC-8936519 https://reactome.org/PathwayBrowser/#/R-SSC-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Sus scrofa 224 R-XTR-209821 https://reactome.org/PathwayBrowser/#/R-XTR-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Xenopus tropicalis 224 R-XTR-8936519 https://reactome.org/PathwayBrowser/#/R-XTR-8936519 NQO2:FAD dimer reduces quinones to hydroquinones IEA Xenopus tropicalis 2285 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 2285 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 2285 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 2285 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 2285 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 2285 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 2285 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 2286 R-BTA-5693691 https://reactome.org/PathwayBrowser/#/R-BTA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Bos taurus 2286 R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans 2286 R-CFA-5693691 https://reactome.org/PathwayBrowser/#/R-CFA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Canis familiaris 2286 R-DDI-5693691 https://reactome.org/PathwayBrowser/#/R-DDI-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Dictyostelium discoideum 2286 R-DME-5693691 https://reactome.org/PathwayBrowser/#/R-DME-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Drosophila melanogaster 2286 R-DRE-5693691 https://reactome.org/PathwayBrowser/#/R-DRE-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Danio rerio 2286 R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus 2286 R-HSA-5693691 https://reactome.org/PathwayBrowser/#/R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG TAS Homo sapiens 2286 R-MMU-5693691 https://reactome.org/PathwayBrowser/#/R-MMU-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Mus musculus 2286 R-RNO-5693691 https://reactome.org/PathwayBrowser/#/R-RNO-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Rattus norvegicus 2286 R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa 2286 R-XTR-5693691 https://reactome.org/PathwayBrowser/#/R-XTR-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Xenopus tropicalis 2290 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 2290 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 2290 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 2290 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 2290 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 2290 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 2290 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 2291 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 2291 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2291 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2291 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2291 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2291 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 2291 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2291 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2291 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2291 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2291 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 2291 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2291 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2291 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 2291 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2291 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2291 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2291 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2291 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 2291 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2291 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2291 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2291 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2291 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2291 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2291 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 2291 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2291 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2291 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2291 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2291 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 2291 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2291 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2291 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 2291 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2291 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2291 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2291 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2291 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 2291 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2291 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2291 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2296 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 2296 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 2296 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 2296 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 2296 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 2296 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 2296 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 2297 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 2297 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 2297 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 2297 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 2297 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 2297 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 2297 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 2298 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2298 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2298 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2298 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2298 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2298 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2298 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2298 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2298 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2298 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 2299 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 2299 R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 2299 R-BTA-9727567 https://reactome.org/PathwayBrowser/#/R-BTA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Bos taurus 2299 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 2299 R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 2299 R-CEL-9727567 https://reactome.org/PathwayBrowser/#/R-CEL-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Caenorhabditis elegans 2299 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 2299 R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 2299 R-CFA-9727567 https://reactome.org/PathwayBrowser/#/R-CFA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Canis familiaris 2299 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 2299 R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 2299 R-DDI-9727567 https://reactome.org/PathwayBrowser/#/R-DDI-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Dictyostelium discoideum 2299 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 2299 R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 2299 R-DME-9727567 https://reactome.org/PathwayBrowser/#/R-DME-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Drosophila melanogaster 2299 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 2299 R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 2299 R-DRE-9727567 https://reactome.org/PathwayBrowser/#/R-DRE-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Danio rerio 2299 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 2299 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 2299 R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus 2299 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 2299 R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 2299 R-HSA-9727567 https://reactome.org/PathwayBrowser/#/R-HSA-9727567 CES1 hydrolyses sacubitril to sacubitrilat TAS Homo sapiens 2299 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 2299 R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 2299 R-MMU-9727567 https://reactome.org/PathwayBrowser/#/R-MMU-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Mus musculus 2299 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 2299 R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 2299 R-RNO-9727567 https://reactome.org/PathwayBrowser/#/R-RNO-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Rattus norvegicus 2299 R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 2299 R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 2299 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 2299 R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 2299 R-SSC-9727567 https://reactome.org/PathwayBrowser/#/R-SSC-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Sus scrofa 2299 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 2299 R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 2299 R-XTR-9727567 https://reactome.org/PathwayBrowser/#/R-XTR-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Xenopus tropicalis 2300 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 2300 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 2300 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 2300 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 2300 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 2300 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 2300 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 2301 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 2301 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 2301 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 2301 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 2301 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 2301 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 2301 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 2313 R-HSA-9931565 https://reactome.org/PathwayBrowser/#/R-HSA-9931565 EmrE dimer exports xenobiotics to periplasm TAS Homo sapiens 2334 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2334 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2334 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2334 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2334 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2334 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2334 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2334 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2334 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2334 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 2337 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 2337 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 2337 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 2337 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 2337 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 2342 R-BTA-597628 https://reactome.org/PathwayBrowser/#/R-BTA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Bos taurus 2342 R-CEL-597628 https://reactome.org/PathwayBrowser/#/R-CEL-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Caenorhabditis elegans 2342 R-CFA-597628 https://reactome.org/PathwayBrowser/#/R-CFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Canis familiaris 2342 R-DRE-597628 https://reactome.org/PathwayBrowser/#/R-DRE-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Danio rerio 2342 R-GGA-597628 https://reactome.org/PathwayBrowser/#/R-GGA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Gallus gallus 2342 R-HSA-5625574 https://reactome.org/PathwayBrowser/#/R-HSA-5625574 Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+ TAS Homo sapiens 2342 R-HSA-597628 https://reactome.org/PathwayBrowser/#/R-HSA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ TAS Homo sapiens 2342 R-MMU-597628 https://reactome.org/PathwayBrowser/#/R-MMU-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Mus musculus 2342 R-PFA-597628 https://reactome.org/PathwayBrowser/#/R-PFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Plasmodium falciparum 2342 R-RNO-597628 https://reactome.org/PathwayBrowser/#/R-RNO-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Rattus norvegicus 2342 R-SSC-597628 https://reactome.org/PathwayBrowser/#/R-SSC-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Sus scrofa 2342 R-XTR-597628 https://reactome.org/PathwayBrowser/#/R-XTR-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Xenopus tropicalis 2347 R-BTA-2514865 https://reactome.org/PathwayBrowser/#/R-BTA-2514865 cGMP dissociates from CNG channels IEA Bos taurus 2347 R-BTA-2514867 https://reactome.org/PathwayBrowser/#/R-BTA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Bos taurus 2347 R-BTA-4086392 https://reactome.org/PathwayBrowser/#/R-BTA-4086392 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 2347 R-BTA-418456 https://reactome.org/PathwayBrowser/#/R-BTA-418456 cGMP is degraded by PDEs IEA Bos taurus 2347 R-BTA-445813 https://reactome.org/PathwayBrowser/#/R-BTA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Bos taurus 2347 R-BTA-561041 https://reactome.org/PathwayBrowser/#/R-BTA-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Bos taurus 2347 R-BTA-74031 https://reactome.org/PathwayBrowser/#/R-BTA-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Bos taurus 2347 R-BTA-74059 https://reactome.org/PathwayBrowser/#/R-BTA-74059 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 2347 R-BTA-74885 https://reactome.org/PathwayBrowser/#/R-BTA-74885 GUCYs converts GTP to cGMP IEA Bos taurus 2347 R-BTA-9653503 https://reactome.org/PathwayBrowser/#/R-BTA-9653503 KRAS4B is phosphorylated on serine 181 IEA Bos taurus 2347 R-CEL-2514865 https://reactome.org/PathwayBrowser/#/R-CEL-2514865 cGMP dissociates from CNG channels IEA Caenorhabditis elegans 2347 R-CEL-2514867 https://reactome.org/PathwayBrowser/#/R-CEL-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Caenorhabditis elegans 2347 R-CEL-418456 https://reactome.org/PathwayBrowser/#/R-CEL-418456 cGMP is degraded by PDEs IEA Caenorhabditis elegans 2347 R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans 2347 R-CEL-74031 https://reactome.org/PathwayBrowser/#/R-CEL-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Caenorhabditis elegans 2347 R-CEL-74885 https://reactome.org/PathwayBrowser/#/R-CEL-74885 GUCYs converts GTP to cGMP IEA Caenorhabditis elegans 2347 R-CFA-2514865 https://reactome.org/PathwayBrowser/#/R-CFA-2514865 cGMP dissociates from CNG channels IEA Canis familiaris 2347 R-CFA-2514867 https://reactome.org/PathwayBrowser/#/R-CFA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Canis familiaris 2347 R-CFA-4086392 https://reactome.org/PathwayBrowser/#/R-CFA-4086392 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 2347 R-CFA-418456 https://reactome.org/PathwayBrowser/#/R-CFA-418456 cGMP is degraded by PDEs IEA Canis familiaris 2347 R-CFA-445813 https://reactome.org/PathwayBrowser/#/R-CFA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Canis familiaris 2347 R-CFA-561041 https://reactome.org/PathwayBrowser/#/R-CFA-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Canis familiaris 2347 R-CFA-74031 https://reactome.org/PathwayBrowser/#/R-CFA-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Canis familiaris 2347 R-CFA-74059 https://reactome.org/PathwayBrowser/#/R-CFA-74059 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 2347 R-CFA-74885 https://reactome.org/PathwayBrowser/#/R-CFA-74885 GUCYs converts GTP to cGMP IEA Canis familiaris 2347 R-CFA-9653503 https://reactome.org/PathwayBrowser/#/R-CFA-9653503 KRAS4B is phosphorylated on serine 181 IEA Canis familiaris 2347 R-DDI-418456 https://reactome.org/PathwayBrowser/#/R-DDI-418456 cGMP is degraded by PDEs IEA Dictyostelium discoideum 2347 R-DDI-74885 https://reactome.org/PathwayBrowser/#/R-DDI-74885 GUCYs converts GTP to cGMP IEA Dictyostelium discoideum 2347 R-DME-2514865 https://reactome.org/PathwayBrowser/#/R-DME-2514865 cGMP dissociates from CNG channels IEA Drosophila melanogaster 2347 R-DME-2514867 https://reactome.org/PathwayBrowser/#/R-DME-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Drosophila melanogaster 2347 R-DME-418456 https://reactome.org/PathwayBrowser/#/R-DME-418456 cGMP is degraded by PDEs IEA Drosophila melanogaster 2347 R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster 2347 R-DME-74031 https://reactome.org/PathwayBrowser/#/R-DME-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Drosophila melanogaster 2347 R-DME-74885 https://reactome.org/PathwayBrowser/#/R-DME-74885 GUCYs converts GTP to cGMP IEA Drosophila melanogaster 2347 R-DME-9653503 https://reactome.org/PathwayBrowser/#/R-DME-9653503 KRAS4B is phosphorylated on serine 181 IEA Drosophila melanogaster 2347 R-DRE-561041 https://reactome.org/PathwayBrowser/#/R-DRE-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Danio rerio 2347 R-GGA-2514865 https://reactome.org/PathwayBrowser/#/R-GGA-2514865 cGMP dissociates from CNG channels IEA Gallus gallus 2347 R-GGA-2514867 https://reactome.org/PathwayBrowser/#/R-GGA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Gallus gallus 2347 R-GGA-4086392 https://reactome.org/PathwayBrowser/#/R-GGA-4086392 PDE6 hydrolyses cGMP to GMP IEA Gallus gallus 2347 R-GGA-418456 https://reactome.org/PathwayBrowser/#/R-GGA-418456 cGMP is degraded by PDEs IEA Gallus gallus 2347 R-GGA-445813 https://reactome.org/PathwayBrowser/#/R-GGA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Gallus gallus 2347 R-GGA-561041 https://reactome.org/PathwayBrowser/#/R-GGA-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Gallus gallus 2347 R-GGA-74031 https://reactome.org/PathwayBrowser/#/R-GGA-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Gallus gallus 2347 R-GGA-9653503 https://reactome.org/PathwayBrowser/#/R-GGA-9653503 KRAS4B is phosphorylated on serine 181 IEA Gallus gallus 2347 R-HAM-427308 https://reactome.org/PathwayBrowser/#/R-HAM-427308 cGMP stimulates Protein Kinase G TAS Homarus americanus 2347 R-HSA-2514865 https://reactome.org/PathwayBrowser/#/R-HSA-2514865 cGMP dissociates from CNG channels TAS Homo sapiens 2347 R-HSA-2514867 https://reactome.org/PathwayBrowser/#/R-HSA-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment TAS Homo sapiens 2347 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 2347 R-HSA-4086392 https://reactome.org/PathwayBrowser/#/R-HSA-4086392 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 2347 R-HSA-418451 https://reactome.org/PathwayBrowser/#/R-HSA-418451 cGMP stimulates Protein Kinase G IEA Homo sapiens 2347 R-HSA-418456 https://reactome.org/PathwayBrowser/#/R-HSA-418456 cGMP is degraded by PDEs TAS Homo sapiens 2347 R-HSA-445813 https://reactome.org/PathwayBrowser/#/R-HSA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains TAS Homo sapiens 2347 R-HSA-4551453 https://reactome.org/PathwayBrowser/#/R-HSA-4551453 PRKG is activated by binding to high levels of cGMP in the absence of WNT signaling IEA Homo sapiens 2347 R-HSA-561041 https://reactome.org/PathwayBrowser/#/R-HSA-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids TAS Homo sapiens 2347 R-HSA-74031 https://reactome.org/PathwayBrowser/#/R-HSA-74031 cGMP binds CNG channel to form cGMP:CNG channel TAS Homo sapiens 2347 R-HSA-74059 https://reactome.org/PathwayBrowser/#/R-HSA-74059 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 2347 R-HSA-74885 https://reactome.org/PathwayBrowser/#/R-HSA-74885 GUCYs converts GTP to cGMP TAS Homo sapiens 2347 R-HSA-9653503 https://reactome.org/PathwayBrowser/#/R-HSA-9653503 KRAS4B is phosphorylated on serine 181 TAS Homo sapiens 2347 R-MMU-2514865 https://reactome.org/PathwayBrowser/#/R-MMU-2514865 cGMP dissociates from CNG channels IEA Mus musculus 2347 R-MMU-2514867 https://reactome.org/PathwayBrowser/#/R-MMU-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Mus musculus 2347 R-MMU-4086392 https://reactome.org/PathwayBrowser/#/R-MMU-4086392 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 2347 R-MMU-418456 https://reactome.org/PathwayBrowser/#/R-MMU-418456 cGMP is degraded by PDEs IEA Mus musculus 2347 R-MMU-445813 https://reactome.org/PathwayBrowser/#/R-MMU-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Mus musculus 2347 R-MMU-4551446 https://reactome.org/PathwayBrowser/#/R-MMU-4551446 Prkg is activated upon cGMP binding TAS Mus musculus 2347 R-MMU-561041 https://reactome.org/PathwayBrowser/#/R-MMU-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Mus musculus 2347 R-MMU-74031 https://reactome.org/PathwayBrowser/#/R-MMU-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Mus musculus 2347 R-MMU-74059 https://reactome.org/PathwayBrowser/#/R-MMU-74059 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 2347 R-MMU-74885 https://reactome.org/PathwayBrowser/#/R-MMU-74885 GUCYs converts GTP to cGMP IEA Mus musculus 2347 R-MMU-9653503 https://reactome.org/PathwayBrowser/#/R-MMU-9653503 KRAS4B is phosphorylated on serine 181 IEA Mus musculus 2347 R-PFA-418456 https://reactome.org/PathwayBrowser/#/R-PFA-418456 cGMP is degraded by PDEs IEA Plasmodium falciparum 2347 R-RNO-2514865 https://reactome.org/PathwayBrowser/#/R-RNO-2514865 cGMP dissociates from CNG channels IEA Rattus norvegicus 2347 R-RNO-2514867 https://reactome.org/PathwayBrowser/#/R-RNO-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Rattus norvegicus 2347 R-RNO-4086392 https://reactome.org/PathwayBrowser/#/R-RNO-4086392 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 2347 R-RNO-418456 https://reactome.org/PathwayBrowser/#/R-RNO-418456 cGMP is degraded by PDEs IEA Rattus norvegicus 2347 R-RNO-427288 https://reactome.org/PathwayBrowser/#/R-RNO-427288 Soluble guanylate cyclase converts GTP to cGMP TAS Rattus norvegicus 2347 R-RNO-445813 https://reactome.org/PathwayBrowser/#/R-RNO-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Rattus norvegicus 2347 R-RNO-561041 https://reactome.org/PathwayBrowser/#/R-RNO-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Rattus norvegicus 2347 R-RNO-74031 https://reactome.org/PathwayBrowser/#/R-RNO-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Rattus norvegicus 2347 R-RNO-74059 https://reactome.org/PathwayBrowser/#/R-RNO-74059 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 2347 R-RNO-74885 https://reactome.org/PathwayBrowser/#/R-RNO-74885 GUCYs converts GTP to cGMP IEA Rattus norvegicus 2347 R-RNO-9653503 https://reactome.org/PathwayBrowser/#/R-RNO-9653503 KRAS4B is phosphorylated on serine 181 IEA Rattus norvegicus 2347 R-SCE-418456 https://reactome.org/PathwayBrowser/#/R-SCE-418456 cGMP is degraded by PDEs IEA Saccharomyces cerevisiae 2347 R-SSC-2514865 https://reactome.org/PathwayBrowser/#/R-SSC-2514865 cGMP dissociates from CNG channels IEA Sus scrofa 2347 R-SSC-2514867 https://reactome.org/PathwayBrowser/#/R-SSC-2514867 cGMP:CNG transports Na+ and Ca2+ into the rod outer segment IEA Sus scrofa 2347 R-SSC-4086392 https://reactome.org/PathwayBrowser/#/R-SSC-4086392 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 2347 R-SSC-418456 https://reactome.org/PathwayBrowser/#/R-SSC-418456 cGMP is degraded by PDEs IEA Sus scrofa 2347 R-SSC-445813 https://reactome.org/PathwayBrowser/#/R-SSC-445813 Phosphorylation of Smooth Muscle Myosin Light Chains IEA Sus scrofa 2347 R-SSC-561041 https://reactome.org/PathwayBrowser/#/R-SSC-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Sus scrofa 2347 R-SSC-74031 https://reactome.org/PathwayBrowser/#/R-SSC-74031 cGMP binds CNG channel to form cGMP:CNG channel IEA Sus scrofa 2347 R-SSC-74059 https://reactome.org/PathwayBrowser/#/R-SSC-74059 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 2347 R-SSC-74885 https://reactome.org/PathwayBrowser/#/R-SSC-74885 GUCYs converts GTP to cGMP IEA Sus scrofa 2347 R-SSC-9653503 https://reactome.org/PathwayBrowser/#/R-SSC-9653503 KRAS4B is phosphorylated on serine 181 IEA Sus scrofa 2347 R-XTR-4086392 https://reactome.org/PathwayBrowser/#/R-XTR-4086392 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 2347 R-XTR-418456 https://reactome.org/PathwayBrowser/#/R-XTR-418456 cGMP is degraded by PDEs IEA Xenopus tropicalis 2347 R-XTR-561041 https://reactome.org/PathwayBrowser/#/R-XTR-561041 OAT1,2,3 transport organic anions with antiport of dicarboxylic acids IEA Xenopus tropicalis 2347 R-XTR-74059 https://reactome.org/PathwayBrowser/#/R-XTR-74059 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 2347 R-XTR-74885 https://reactome.org/PathwayBrowser/#/R-XTR-74885 GUCYs converts GTP to cGMP IEA Xenopus tropicalis 2350 R-BTA-1467466 https://reactome.org/PathwayBrowser/#/R-BTA-1467466 ABCA4 mediates atRAL transport IEA Bos taurus 2350 R-BTA-2399913 https://reactome.org/PathwayBrowser/#/R-BTA-2399913 atRAL binds to RBP2 IEA Bos taurus 2350 R-BTA-2464776 https://reactome.org/PathwayBrowser/#/R-BTA-2464776 Rdh8 reduces atRAL to atROL TAS Bos taurus 2350 R-BTA-2464822 https://reactome.org/PathwayBrowser/#/R-BTA-2464822 RDH12 reduces atRAL to atROL IEA Bos taurus 2350 R-BTA-2465940 https://reactome.org/PathwayBrowser/#/R-BTA-2465940 atRAL is reduced to atROL IEA Bos taurus 2350 R-BTA-2466085 https://reactome.org/PathwayBrowser/#/R-BTA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Bos taurus 2350 R-BTA-2530504 https://reactome.org/PathwayBrowser/#/R-BTA-2530504 MII catalyses GDP/GTP exchange on Gt TAS Bos taurus 2350 R-BTA-2581495 https://reactome.org/PathwayBrowser/#/R-BTA-2581495 Sag binds p-MII to form p-MII:Sag TAS Bos taurus 2350 R-BTA-2632521 https://reactome.org/PathwayBrowser/#/R-BTA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Bos taurus 2350 R-BTA-2855252 https://reactome.org/PathwayBrowser/#/R-BTA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Bos taurus 2350 R-BTA-5362518 https://reactome.org/PathwayBrowser/#/R-BTA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Bos taurus 2350 R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 2350 R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 2350 R-BTA-5419165 https://reactome.org/PathwayBrowser/#/R-BTA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Bos taurus 2350 R-BTA-5615668 https://reactome.org/PathwayBrowser/#/R-BTA-5615668 AKR1C3 reduces atRAL to atROL IEA Bos taurus 2350 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 2350 R-BTA-74831 https://reactome.org/PathwayBrowser/#/R-BTA-74831 p-MII:Sag dissociates to p-Rho and Sag TAS Bos taurus 2350 R-BTA-975629 https://reactome.org/PathwayBrowser/#/R-BTA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Bos taurus 2350 R-BTA-975635 https://reactome.org/PathwayBrowser/#/R-BTA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Bos taurus 2350 R-CEL-1467466 https://reactome.org/PathwayBrowser/#/R-CEL-1467466 ABCA4 mediates atRAL transport IEA Caenorhabditis elegans 2350 R-CEL-2399913 https://reactome.org/PathwayBrowser/#/R-CEL-2399913 atRAL binds to RBP2 IEA Caenorhabditis elegans 2350 R-CEL-2465940 https://reactome.org/PathwayBrowser/#/R-CEL-2465940 atRAL is reduced to atROL IEA Caenorhabditis elegans 2350 R-CEL-2466085 https://reactome.org/PathwayBrowser/#/R-CEL-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Caenorhabditis elegans 2350 R-CEL-2632521 https://reactome.org/PathwayBrowser/#/R-CEL-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Caenorhabditis elegans 2350 R-CEL-2855252 https://reactome.org/PathwayBrowser/#/R-CEL-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Caenorhabditis elegans 2350 R-CEL-5362518 https://reactome.org/PathwayBrowser/#/R-CEL-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Caenorhabditis elegans 2350 R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 2350 R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 2350 R-CEL-5419165 https://reactome.org/PathwayBrowser/#/R-CEL-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Caenorhabditis elegans 2350 R-CEL-5615668 https://reactome.org/PathwayBrowser/#/R-CEL-5615668 AKR1C3 reduces atRAL to atROL IEA Caenorhabditis elegans 2350 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 2350 R-CEL-975635 https://reactome.org/PathwayBrowser/#/R-CEL-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Caenorhabditis elegans 2350 R-CFA-1467466 https://reactome.org/PathwayBrowser/#/R-CFA-1467466 ABCA4 mediates atRAL transport IEA Canis familiaris 2350 R-CFA-2399913 https://reactome.org/PathwayBrowser/#/R-CFA-2399913 atRAL binds to RBP2 IEA Canis familiaris 2350 R-CFA-2464822 https://reactome.org/PathwayBrowser/#/R-CFA-2464822 RDH12 reduces atRAL to atROL IEA Canis familiaris 2350 R-CFA-2465940 https://reactome.org/PathwayBrowser/#/R-CFA-2465940 atRAL is reduced to atROL IEA Canis familiaris 2350 R-CFA-2466085 https://reactome.org/PathwayBrowser/#/R-CFA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Canis familiaris 2350 R-CFA-2632521 https://reactome.org/PathwayBrowser/#/R-CFA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Canis familiaris 2350 R-CFA-5362518 https://reactome.org/PathwayBrowser/#/R-CFA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Canis familiaris 2350 R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 2350 R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 2350 R-CFA-5419165 https://reactome.org/PathwayBrowser/#/R-CFA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Canis familiaris 2350 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 2350 R-CFA-975635 https://reactome.org/PathwayBrowser/#/R-CFA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Canis familiaris 2350 R-DDI-1467466 https://reactome.org/PathwayBrowser/#/R-DDI-1467466 ABCA4 mediates atRAL transport IEA Dictyostelium discoideum 2350 R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 2350 R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 2350 R-DDI-5419165 https://reactome.org/PathwayBrowser/#/R-DDI-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Dictyostelium discoideum 2350 R-DDI-5615668 https://reactome.org/PathwayBrowser/#/R-DDI-5615668 AKR1C3 reduces atRAL to atROL IEA Dictyostelium discoideum 2350 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 2350 R-DME-1467466 https://reactome.org/PathwayBrowser/#/R-DME-1467466 ABCA4 mediates atRAL transport IEA Drosophila melanogaster 2350 R-DME-2399913 https://reactome.org/PathwayBrowser/#/R-DME-2399913 atRAL binds to RBP2 IEA Drosophila melanogaster 2350 R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster 2350 R-DME-2465940 https://reactome.org/PathwayBrowser/#/R-DME-2465940 atRAL is reduced to atROL IEA Drosophila melanogaster 2350 R-DME-2855252 https://reactome.org/PathwayBrowser/#/R-DME-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 2350 R-DME-5362518 https://reactome.org/PathwayBrowser/#/R-DME-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Drosophila melanogaster 2350 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 2350 R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 2350 R-DME-5419165 https://reactome.org/PathwayBrowser/#/R-DME-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Drosophila melanogaster 2350 R-DME-5615668 https://reactome.org/PathwayBrowser/#/R-DME-5615668 AKR1C3 reduces atRAL to atROL IEA Drosophila melanogaster 2350 R-DME-975629 https://reactome.org/PathwayBrowser/#/R-DME-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 2350 R-DME-975635 https://reactome.org/PathwayBrowser/#/R-DME-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Drosophila melanogaster 2350 R-DRE-2399913 https://reactome.org/PathwayBrowser/#/R-DRE-2399913 atRAL binds to RBP2 IEA Danio rerio 2350 R-DRE-2464822 https://reactome.org/PathwayBrowser/#/R-DRE-2464822 RDH12 reduces atRAL to atROL IEA Danio rerio 2350 R-DRE-2465940 https://reactome.org/PathwayBrowser/#/R-DRE-2465940 atRAL is reduced to atROL IEA Danio rerio 2350 R-DRE-2466085 https://reactome.org/PathwayBrowser/#/R-DRE-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Danio rerio 2350 R-DRE-2632521 https://reactome.org/PathwayBrowser/#/R-DRE-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Danio rerio 2350 R-DRE-2855252 https://reactome.org/PathwayBrowser/#/R-DRE-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Danio rerio 2350 R-DRE-5362518 https://reactome.org/PathwayBrowser/#/R-DRE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Danio rerio 2350 R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 2350 R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 2350 R-DRE-5419165 https://reactome.org/PathwayBrowser/#/R-DRE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Danio rerio 2350 R-DRE-975629 https://reactome.org/PathwayBrowser/#/R-DRE-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Danio rerio 2350 R-DRE-975635 https://reactome.org/PathwayBrowser/#/R-DRE-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Danio rerio 2350 R-GGA-1467466 https://reactome.org/PathwayBrowser/#/R-GGA-1467466 ABCA4 mediates atRAL transport IEA Gallus gallus 2350 R-GGA-2399913 https://reactome.org/PathwayBrowser/#/R-GGA-2399913 atRAL binds to RBP2 IEA Gallus gallus 2350 R-GGA-2464822 https://reactome.org/PathwayBrowser/#/R-GGA-2464822 RDH12 reduces atRAL to atROL IEA Gallus gallus 2350 R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus 2350 R-GGA-2466085 https://reactome.org/PathwayBrowser/#/R-GGA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Gallus gallus 2350 R-GGA-2632521 https://reactome.org/PathwayBrowser/#/R-GGA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Gallus gallus 2350 R-GGA-2855252 https://reactome.org/PathwayBrowser/#/R-GGA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Gallus gallus 2350 R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus 2350 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 2350 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 2350 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus 2350 R-GGA-975629 https://reactome.org/PathwayBrowser/#/R-GGA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Gallus gallus 2350 R-GGA-975635 https://reactome.org/PathwayBrowser/#/R-GGA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Gallus gallus 2350 R-HSA-1467466 https://reactome.org/PathwayBrowser/#/R-HSA-1467466 ABCA4 mediates atRAL transport TAS Homo sapiens 2350 R-HSA-2399913 https://reactome.org/PathwayBrowser/#/R-HSA-2399913 atRAL binds to RBP2 TAS Homo sapiens 2350 R-HSA-2464803 https://reactome.org/PathwayBrowser/#/R-HSA-2464803 RDH8 reduces atRAL to atROL IEA Homo sapiens 2350 R-HSA-2464810 https://reactome.org/PathwayBrowser/#/R-HSA-2464810 atRAL(membrane) diffuses to atRAL(cytosol) TAS Homo sapiens 2350 R-HSA-2464822 https://reactome.org/PathwayBrowser/#/R-HSA-2464822 RDH12 reduces atRAL to atROL TAS Homo sapiens 2350 R-HSA-2465940 https://reactome.org/PathwayBrowser/#/R-HSA-2465940 atRAL is reduced to atROL TAS Homo sapiens 2350 R-HSA-2466085 https://reactome.org/PathwayBrowser/#/R-HSA-2466085 at-retinyl is hydrolysed from R* to release atRAL TAS Homo sapiens 2350 R-HSA-2466718 https://reactome.org/PathwayBrowser/#/R-HSA-2466718 NRPE dissociates to atRAL and PE TAS Homo sapiens 2350 R-HSA-2466764 https://reactome.org/PathwayBrowser/#/R-HSA-2466764 NRPE condenses with atRAL to form A2PE TAS Homo sapiens 2350 R-HSA-2466846 https://reactome.org/PathwayBrowser/#/R-HSA-2466846 atRAL can spontaneously react with PE to form NRPE TAS Homo sapiens 2350 R-HSA-2466861 https://reactome.org/PathwayBrowser/#/R-HSA-2466861 Defective RDH12 does not reduce atRAL to atROL TAS Homo sapiens 2350 R-HSA-2632521 https://reactome.org/PathwayBrowser/#/R-HSA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL TAS Homo sapiens 2350 R-HSA-2855252 https://reactome.org/PathwayBrowser/#/R-HSA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL TAS Homo sapiens 2350 R-HSA-5362518 https://reactome.org/PathwayBrowser/#/R-HSA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL TAS Homo sapiens 2350 R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 2350 R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 2350 R-HSA-5419165 https://reactome.org/PathwayBrowser/#/R-HSA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL TAS Homo sapiens 2350 R-HSA-5615668 https://reactome.org/PathwayBrowser/#/R-HSA-5615668 AKR1C3 reduces atRAL to atROL TAS Homo sapiens 2350 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 2350 R-HSA-975629 https://reactome.org/PathwayBrowser/#/R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL TAS Homo sapiens 2350 R-HSA-975635 https://reactome.org/PathwayBrowser/#/R-HSA-975635 BCMO1:Fe2+ cleaves betaC to atRAL TAS Homo sapiens 2350 R-MMU-1467466 https://reactome.org/PathwayBrowser/#/R-MMU-1467466 ABCA4 mediates atRAL transport IEA Mus musculus 2350 R-MMU-2399913 https://reactome.org/PathwayBrowser/#/R-MMU-2399913 atRAL binds to RBP2 IEA Mus musculus 2350 R-MMU-2464822 https://reactome.org/PathwayBrowser/#/R-MMU-2464822 RDH12 reduces atRAL to atROL IEA Mus musculus 2350 R-MMU-2465940 https://reactome.org/PathwayBrowser/#/R-MMU-2465940 atRAL is reduced to atROL IEA Mus musculus 2350 R-MMU-2466085 https://reactome.org/PathwayBrowser/#/R-MMU-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Mus musculus 2350 R-MMU-2632521 https://reactome.org/PathwayBrowser/#/R-MMU-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Mus musculus 2350 R-MMU-2855252 https://reactome.org/PathwayBrowser/#/R-MMU-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Mus musculus 2350 R-MMU-5362518 https://reactome.org/PathwayBrowser/#/R-MMU-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Mus musculus 2350 R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 2350 R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 2350 R-MMU-5419165 https://reactome.org/PathwayBrowser/#/R-MMU-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Mus musculus 2350 R-MMU-5615668 https://reactome.org/PathwayBrowser/#/R-MMU-5615668 AKR1C3 reduces atRAL to atROL IEA Mus musculus 2350 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 2350 R-MMU-975629 https://reactome.org/PathwayBrowser/#/R-MMU-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Mus musculus 2350 R-MMU-975635 https://reactome.org/PathwayBrowser/#/R-MMU-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Mus musculus 2350 R-PFA-1467466 https://reactome.org/PathwayBrowser/#/R-PFA-1467466 ABCA4 mediates atRAL transport IEA Plasmodium falciparum 2350 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 2350 R-RNO-2399913 https://reactome.org/PathwayBrowser/#/R-RNO-2399913 atRAL binds to RBP2 IEA Rattus norvegicus 2350 R-RNO-2464822 https://reactome.org/PathwayBrowser/#/R-RNO-2464822 RDH12 reduces atRAL to atROL IEA Rattus norvegicus 2350 R-RNO-2465940 https://reactome.org/PathwayBrowser/#/R-RNO-2465940 atRAL is reduced to atROL IEA Rattus norvegicus 2350 R-RNO-2466085 https://reactome.org/PathwayBrowser/#/R-RNO-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Rattus norvegicus 2350 R-RNO-2632521 https://reactome.org/PathwayBrowser/#/R-RNO-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Rattus norvegicus 2350 R-RNO-2855252 https://reactome.org/PathwayBrowser/#/R-RNO-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 2350 R-RNO-5362518 https://reactome.org/PathwayBrowser/#/R-RNO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Rattus norvegicus 2350 R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 2350 R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 2350 R-RNO-5419165 https://reactome.org/PathwayBrowser/#/R-RNO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Rattus norvegicus 2350 R-RNO-5615668 https://reactome.org/PathwayBrowser/#/R-RNO-5615668 AKR1C3 reduces atRAL to atROL IEA Rattus norvegicus 2350 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 2350 R-RNO-975629 https://reactome.org/PathwayBrowser/#/R-RNO-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 2350 R-RNO-975635 https://reactome.org/PathwayBrowser/#/R-RNO-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Rattus norvegicus 2350 R-SCE-2465940 https://reactome.org/PathwayBrowser/#/R-SCE-2465940 atRAL is reduced to atROL IEA Saccharomyces cerevisiae 2350 R-SCE-5362518 https://reactome.org/PathwayBrowser/#/R-SCE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Saccharomyces cerevisiae 2350 R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 2350 R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 2350 R-SCE-5419165 https://reactome.org/PathwayBrowser/#/R-SCE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Saccharomyces cerevisiae 2350 R-SCE-5615668 https://reactome.org/PathwayBrowser/#/R-SCE-5615668 AKR1C3 reduces atRAL to atROL IEA Saccharomyces cerevisiae 2350 R-SPO-5362518 https://reactome.org/PathwayBrowser/#/R-SPO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Schizosaccharomyces pombe 2350 R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 2350 R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 2350 R-SPO-5419165 https://reactome.org/PathwayBrowser/#/R-SPO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Schizosaccharomyces pombe 2350 R-SPO-5615668 https://reactome.org/PathwayBrowser/#/R-SPO-5615668 AKR1C3 reduces atRAL to atROL IEA Schizosaccharomyces pombe 2350 R-SSC-1467466 https://reactome.org/PathwayBrowser/#/R-SSC-1467466 ABCA4 mediates atRAL transport IEA Sus scrofa 2350 R-SSC-2399913 https://reactome.org/PathwayBrowser/#/R-SSC-2399913 atRAL binds to RBP2 IEA Sus scrofa 2350 R-SSC-2464822 https://reactome.org/PathwayBrowser/#/R-SSC-2464822 RDH12 reduces atRAL to atROL IEA Sus scrofa 2350 R-SSC-2465940 https://reactome.org/PathwayBrowser/#/R-SSC-2465940 atRAL is reduced to atROL IEA Sus scrofa 2350 R-SSC-2466085 https://reactome.org/PathwayBrowser/#/R-SSC-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Sus scrofa 2350 R-SSC-2632521 https://reactome.org/PathwayBrowser/#/R-SSC-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Sus scrofa 2350 R-SSC-2855252 https://reactome.org/PathwayBrowser/#/R-SSC-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Sus scrofa 2350 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa 2350 R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 2350 R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 2350 R-SSC-5419165 https://reactome.org/PathwayBrowser/#/R-SSC-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Sus scrofa 2350 R-SSC-5615668 https://reactome.org/PathwayBrowser/#/R-SSC-5615668 AKR1C3 reduces atRAL to atROL IEA Sus scrofa 2350 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 2350 R-SSC-975629 https://reactome.org/PathwayBrowser/#/R-SSC-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Sus scrofa 2350 R-SSC-975635 https://reactome.org/PathwayBrowser/#/R-SSC-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Sus scrofa 2350 R-XTR-1467466 https://reactome.org/PathwayBrowser/#/R-XTR-1467466 ABCA4 mediates atRAL transport IEA Xenopus tropicalis 2350 R-XTR-2399913 https://reactome.org/PathwayBrowser/#/R-XTR-2399913 atRAL binds to RBP2 IEA Xenopus tropicalis 2350 R-XTR-2465940 https://reactome.org/PathwayBrowser/#/R-XTR-2465940 atRAL is reduced to atROL IEA Xenopus tropicalis 2350 R-XTR-2466085 https://reactome.org/PathwayBrowser/#/R-XTR-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Xenopus tropicalis 2350 R-XTR-2855252 https://reactome.org/PathwayBrowser/#/R-XTR-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Xenopus tropicalis 2350 R-XTR-5362518 https://reactome.org/PathwayBrowser/#/R-XTR-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Xenopus tropicalis 2350 R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 2350 R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 2350 R-XTR-5419165 https://reactome.org/PathwayBrowser/#/R-XTR-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Xenopus tropicalis 2350 R-XTR-5615668 https://reactome.org/PathwayBrowser/#/R-XTR-5615668 AKR1C3 reduces atRAL to atROL IEA Xenopus tropicalis 2350 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 2350 R-XTR-975635 https://reactome.org/PathwayBrowser/#/R-XTR-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Xenopus tropicalis 2355 R-BTA-9726875 https://reactome.org/PathwayBrowser/#/R-BTA-9726875 HCNs:cAMP bind SNIs IEA Bos taurus 2355 R-CFA-9726875 https://reactome.org/PathwayBrowser/#/R-CFA-9726875 HCNs:cAMP bind SNIs IEA Canis familiaris 2355 R-DME-9726875 https://reactome.org/PathwayBrowser/#/R-DME-9726875 HCNs:cAMP bind SNIs IEA Drosophila melanogaster 2355 R-GGA-9726875 https://reactome.org/PathwayBrowser/#/R-GGA-9726875 HCNs:cAMP bind SNIs IEA Gallus gallus 2355 R-HSA-9726875 https://reactome.org/PathwayBrowser/#/R-HSA-9726875 HCNs:cAMP bind SNIs TAS Homo sapiens 2355 R-MMU-9726875 https://reactome.org/PathwayBrowser/#/R-MMU-9726875 HCNs:cAMP bind SNIs IEA Mus musculus 2355 R-RNO-9726875 https://reactome.org/PathwayBrowser/#/R-RNO-9726875 HCNs:cAMP bind SNIs IEA Rattus norvegicus 2355 R-SSC-9726875 https://reactome.org/PathwayBrowser/#/R-SSC-9726875 HCNs:cAMP bind SNIs IEA Sus scrofa 2355 R-XTR-9726875 https://reactome.org/PathwayBrowser/#/R-XTR-9726875 HCNs:cAMP bind SNIs IEA Xenopus tropicalis 2357 R-BTA-9726875 https://reactome.org/PathwayBrowser/#/R-BTA-9726875 HCNs:cAMP bind SNIs IEA Bos taurus 2357 R-CFA-9726875 https://reactome.org/PathwayBrowser/#/R-CFA-9726875 HCNs:cAMP bind SNIs IEA Canis familiaris 2357 R-DME-9726875 https://reactome.org/PathwayBrowser/#/R-DME-9726875 HCNs:cAMP bind SNIs IEA Drosophila melanogaster 2357 R-GGA-9726875 https://reactome.org/PathwayBrowser/#/R-GGA-9726875 HCNs:cAMP bind SNIs IEA Gallus gallus 2357 R-HSA-9726875 https://reactome.org/PathwayBrowser/#/R-HSA-9726875 HCNs:cAMP bind SNIs TAS Homo sapiens 2357 R-MMU-9726875 https://reactome.org/PathwayBrowser/#/R-MMU-9726875 HCNs:cAMP bind SNIs IEA Mus musculus 2357 R-RNO-9726875 https://reactome.org/PathwayBrowser/#/R-RNO-9726875 HCNs:cAMP bind SNIs IEA Rattus norvegicus 2357 R-SSC-9726875 https://reactome.org/PathwayBrowser/#/R-SSC-9726875 HCNs:cAMP bind SNIs IEA Sus scrofa 2357 R-XTR-9726875 https://reactome.org/PathwayBrowser/#/R-XTR-9726875 HCNs:cAMP bind SNIs IEA Xenopus tropicalis 2358 R-BTA-9726875 https://reactome.org/PathwayBrowser/#/R-BTA-9726875 HCNs:cAMP bind SNIs IEA Bos taurus 2358 R-CFA-9726875 https://reactome.org/PathwayBrowser/#/R-CFA-9726875 HCNs:cAMP bind SNIs IEA Canis familiaris 2358 R-DME-9726875 https://reactome.org/PathwayBrowser/#/R-DME-9726875 HCNs:cAMP bind SNIs IEA Drosophila melanogaster 2358 R-GGA-9726875 https://reactome.org/PathwayBrowser/#/R-GGA-9726875 HCNs:cAMP bind SNIs IEA Gallus gallus 2358 R-HSA-9726875 https://reactome.org/PathwayBrowser/#/R-HSA-9726875 HCNs:cAMP bind SNIs TAS Homo sapiens 2358 R-MMU-9726875 https://reactome.org/PathwayBrowser/#/R-MMU-9726875 HCNs:cAMP bind SNIs IEA Mus musculus 2358 R-RNO-9726875 https://reactome.org/PathwayBrowser/#/R-RNO-9726875 HCNs:cAMP bind SNIs IEA Rattus norvegicus 2358 R-SSC-9726875 https://reactome.org/PathwayBrowser/#/R-SSC-9726875 HCNs:cAMP bind SNIs IEA Sus scrofa 2358 R-XTR-9726875 https://reactome.org/PathwayBrowser/#/R-XTR-9726875 HCNs:cAMP bind SNIs IEA Xenopus tropicalis 2364 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2364 R-BTA-419426 https://reactome.org/PathwayBrowser/#/R-BTA-419426 Cannabinoid receptors can bind cannabinoids IEA Bos taurus 2364 R-BTA-5693742 https://reactome.org/PathwayBrowser/#/R-BTA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Bos taurus 2364 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 2364 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2364 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2364 R-CEL-5693742 https://reactome.org/PathwayBrowser/#/R-CEL-5693742 FAAH hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 2364 R-CEL-5693751 https://reactome.org/PathwayBrowser/#/R-CEL-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 2364 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 2364 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2364 R-CFA-419426 https://reactome.org/PathwayBrowser/#/R-CFA-419426 Cannabinoid receptors can bind cannabinoids IEA Canis familiaris 2364 R-CFA-5693742 https://reactome.org/PathwayBrowser/#/R-CFA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Canis familiaris 2364 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2364 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2364 R-DME-5693751 https://reactome.org/PathwayBrowser/#/R-DME-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Drosophila melanogaster 2364 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2364 R-DRE-419426 https://reactome.org/PathwayBrowser/#/R-DRE-419426 Cannabinoid receptors can bind cannabinoids IEA Danio rerio 2364 R-DRE-5693751 https://reactome.org/PathwayBrowser/#/R-DRE-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Danio rerio 2364 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2364 R-GGA-419426 https://reactome.org/PathwayBrowser/#/R-GGA-419426 Cannabinoid receptors can bind cannabinoids IEA Gallus gallus 2364 R-GGA-5693742 https://reactome.org/PathwayBrowser/#/R-GGA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Gallus gallus 2364 R-GGA-5693751 https://reactome.org/PathwayBrowser/#/R-GGA-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Gallus gallus 2364 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 2364 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2364 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2364 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2364 R-HSA-419426 https://reactome.org/PathwayBrowser/#/R-HSA-419426 Cannabinoid receptors can bind cannabinoids TAS Homo sapiens 2364 R-HSA-5693742 https://reactome.org/PathwayBrowser/#/R-HSA-5693742 FAAH hydrolyses AEA to AA and ETA TAS Homo sapiens 2364 R-HSA-5693751 https://reactome.org/PathwayBrowser/#/R-HSA-5693751 FAAH2 hydrolyses AEA to AA and ETA TAS Homo sapiens 2364 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 2364 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2364 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2364 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2364 R-MMU-419426 https://reactome.org/PathwayBrowser/#/R-MMU-419426 Cannabinoid receptors can bind cannabinoids IEA Mus musculus 2364 R-MMU-5693742 https://reactome.org/PathwayBrowser/#/R-MMU-5693742 FAAH hydrolyses AEA to AA and ETA IEA Mus musculus 2364 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 2364 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2364 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2364 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2364 R-RNO-419426 https://reactome.org/PathwayBrowser/#/R-RNO-419426 Cannabinoid receptors can bind cannabinoids IEA Rattus norvegicus 2364 R-RNO-5693742 https://reactome.org/PathwayBrowser/#/R-RNO-5693742 FAAH hydrolyses AEA to AA and ETA IEA Rattus norvegicus 2364 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 2364 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2364 R-SSC-419426 https://reactome.org/PathwayBrowser/#/R-SSC-419426 Cannabinoid receptors can bind cannabinoids IEA Sus scrofa 2364 R-SSC-5693742 https://reactome.org/PathwayBrowser/#/R-SSC-5693742 FAAH hydrolyses AEA to AA and ETA IEA Sus scrofa 2364 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 2364 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2364 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2364 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2364 R-XTR-419426 https://reactome.org/PathwayBrowser/#/R-XTR-419426 Cannabinoid receptors can bind cannabinoids IEA Xenopus tropicalis 2364 R-XTR-5693742 https://reactome.org/PathwayBrowser/#/R-XTR-5693742 FAAH hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 2364 R-XTR-5693751 https://reactome.org/PathwayBrowser/#/R-XTR-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 2364 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 2364 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2364 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2367 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 2367 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 2367 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 2367 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 2367 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 2367 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 2367 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 2367 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 2367 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 2367 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 2367 R-HSA-9685830 https://reactome.org/PathwayBrowser/#/R-HSA-9685830 TUBB binds colchicine TAS Homo sapiens 2367 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 2367 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 2367 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 2367 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 2367 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 2367 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 2367 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 2367 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 2367 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 2367 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 2370 R-BTA-176631 https://reactome.org/PathwayBrowser/#/R-BTA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Bos taurus 2370 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 2370 R-BTA-193073 https://reactome.org/PathwayBrowser/#/R-BTA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Bos taurus 2370 R-CFA-176631 https://reactome.org/PathwayBrowser/#/R-CFA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Canis familiaris 2370 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 2370 R-CFA-193073 https://reactome.org/PathwayBrowser/#/R-CFA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Canis familiaris 2370 R-DME-176631 https://reactome.org/PathwayBrowser/#/R-DME-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Drosophila melanogaster 2370 R-DRE-176631 https://reactome.org/PathwayBrowser/#/R-DRE-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Danio rerio 2370 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 2370 R-DRE-193073 https://reactome.org/PathwayBrowser/#/R-DRE-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Danio rerio 2370 R-GGA-176631 https://reactome.org/PathwayBrowser/#/R-GGA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Gallus gallus 2370 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 2370 R-GGA-193073 https://reactome.org/PathwayBrowser/#/R-GGA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Gallus gallus 2370 R-HSA-176631 https://reactome.org/PathwayBrowser/#/R-HSA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP TAS Homo sapiens 2370 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 2370 R-HSA-193073 https://reactome.org/PathwayBrowser/#/R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST TAS Homo sapiens 2370 R-MMU-176631 https://reactome.org/PathwayBrowser/#/R-MMU-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Mus musculus 2370 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 2370 R-MMU-193073 https://reactome.org/PathwayBrowser/#/R-MMU-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Mus musculus 2370 R-RNO-176631 https://reactome.org/PathwayBrowser/#/R-RNO-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Rattus norvegicus 2370 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 2370 R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus 2370 R-SSC-176631 https://reactome.org/PathwayBrowser/#/R-SSC-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Sus scrofa 2370 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 2370 R-SSC-193073 https://reactome.org/PathwayBrowser/#/R-SSC-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Sus scrofa 2370 R-XTR-176631 https://reactome.org/PathwayBrowser/#/R-XTR-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP IEA Xenopus tropicalis 2370 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 2376 R-BTA-176517 https://reactome.org/PathwayBrowser/#/R-BTA-176517 SULTs transfer (SO4)2- group to PREG IEA Bos taurus 2376 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 2376 R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 2376 R-BTA-196350 https://reactome.org/PathwayBrowser/#/R-BTA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Bos taurus 2376 R-CFA-176517 https://reactome.org/PathwayBrowser/#/R-CFA-176517 SULTs transfer (SO4)2- group to PREG IEA Canis familiaris 2376 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 2376 R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 2376 R-CFA-196350 https://reactome.org/PathwayBrowser/#/R-CFA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Canis familiaris 2376 R-DME-176517 https://reactome.org/PathwayBrowser/#/R-DME-176517 SULTs transfer (SO4)2- group to PREG IEA Drosophila melanogaster 2376 R-DRE-176517 https://reactome.org/PathwayBrowser/#/R-DRE-176517 SULTs transfer (SO4)2- group to PREG IEA Danio rerio 2376 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 2376 R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 2376 R-DRE-196350 https://reactome.org/PathwayBrowser/#/R-DRE-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Danio rerio 2376 R-GGA-176517 https://reactome.org/PathwayBrowser/#/R-GGA-176517 SULTs transfer (SO4)2- group to PREG IEA Gallus gallus 2376 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 2376 R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 2376 R-GGA-196350 https://reactome.org/PathwayBrowser/#/R-GGA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Gallus gallus 2376 R-HSA-176517 https://reactome.org/PathwayBrowser/#/R-HSA-176517 SULTs transfer (SO4)2- group to PREG TAS Homo sapiens 2376 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 2376 R-HSA-193097 https://reactome.org/PathwayBrowser/#/R-HSA-193097 Pregnenolone translocates from the mitochondrial matrix to the cytosol TAS Homo sapiens 2376 R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 2376 R-HSA-196350 https://reactome.org/PathwayBrowser/#/R-HSA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione TAS Homo sapiens 2376 R-HSA-5601843 https://reactome.org/PathwayBrowser/#/R-HSA-5601843 Defective CYP17A1 does not 17-hydroxylate PREG TAS Homo sapiens 2376 R-MMU-176517 https://reactome.org/PathwayBrowser/#/R-MMU-176517 SULTs transfer (SO4)2- group to PREG IEA Mus musculus 2376 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 2376 R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 2376 R-MMU-196350 https://reactome.org/PathwayBrowser/#/R-MMU-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Mus musculus 2376 R-RNO-176517 https://reactome.org/PathwayBrowser/#/R-RNO-176517 SULTs transfer (SO4)2- group to PREG IEA Rattus norvegicus 2376 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 2376 R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 2376 R-RNO-196350 https://reactome.org/PathwayBrowser/#/R-RNO-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Rattus norvegicus 2376 R-SSC-176517 https://reactome.org/PathwayBrowser/#/R-SSC-176517 SULTs transfer (SO4)2- group to PREG IEA Sus scrofa 2376 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 2376 R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 2376 R-SSC-196350 https://reactome.org/PathwayBrowser/#/R-SSC-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Sus scrofa 2376 R-XTR-176517 https://reactome.org/PathwayBrowser/#/R-XTR-176517 SULTs transfer (SO4)2- group to PREG IEA Xenopus tropicalis 2376 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 2376 R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 2377 R-BTA-1449687 https://reactome.org/PathwayBrowser/#/R-BTA-1449687 Corticosteroids bind to CBG in blood IEA Bos taurus 2377 R-BTA-193052 https://reactome.org/PathwayBrowser/#/R-BTA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Bos taurus 2377 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 2377 R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 2377 R-BTA-2534359 https://reactome.org/PathwayBrowser/#/R-BTA-2534359 CatSper Channel Mediated Calcium Transport IEA Bos taurus 2377 R-BTA-2534388 https://reactome.org/PathwayBrowser/#/R-BTA-2534388 Progesterone Activation Of CatSper IEA Bos taurus 2377 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 2377 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 2377 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 2377 R-BTA-9038161 https://reactome.org/PathwayBrowser/#/R-BTA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Bos taurus 2377 R-BTA-9038163 https://reactome.org/PathwayBrowser/#/R-BTA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Bos taurus 2377 R-BTA-9725885 https://reactome.org/PathwayBrowser/#/R-BTA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Bos taurus 2377 R-CEL-1449687 https://reactome.org/PathwayBrowser/#/R-CEL-1449687 Corticosteroids bind to CBG in blood IEA Caenorhabditis elegans 2377 R-CFA-1449687 https://reactome.org/PathwayBrowser/#/R-CFA-1449687 Corticosteroids bind to CBG in blood IEA Canis familiaris 2377 R-CFA-193052 https://reactome.org/PathwayBrowser/#/R-CFA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Canis familiaris 2377 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 2377 R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 2377 R-CFA-2534359 https://reactome.org/PathwayBrowser/#/R-CFA-2534359 CatSper Channel Mediated Calcium Transport IEA Canis familiaris 2377 R-CFA-2534388 https://reactome.org/PathwayBrowser/#/R-CFA-2534388 Progesterone Activation Of CatSper IEA Canis familiaris 2377 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 2377 R-CFA-9725885 https://reactome.org/PathwayBrowser/#/R-CFA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Canis familiaris 2377 R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 2377 R-DME-1449687 https://reactome.org/PathwayBrowser/#/R-DME-1449687 Corticosteroids bind to CBG in blood IEA Drosophila melanogaster 2377 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 2377 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 2377 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 2377 R-DME-9038161 https://reactome.org/PathwayBrowser/#/R-DME-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Drosophila melanogaster 2377 R-DME-9725885 https://reactome.org/PathwayBrowser/#/R-DME-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2377 R-DRE-1449687 https://reactome.org/PathwayBrowser/#/R-DRE-1449687 Corticosteroids bind to CBG in blood IEA Danio rerio 2377 R-DRE-193052 https://reactome.org/PathwayBrowser/#/R-DRE-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Danio rerio 2377 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 2377 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 2377 R-DRE-9038163 https://reactome.org/PathwayBrowser/#/R-DRE-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Danio rerio 2377 R-DRE-9725885 https://reactome.org/PathwayBrowser/#/R-DRE-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Danio rerio 2377 R-GGA-193052 https://reactome.org/PathwayBrowser/#/R-GGA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Gallus gallus 2377 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 2377 R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 2377 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 2377 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 2377 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 2377 R-GGA-9038161 https://reactome.org/PathwayBrowser/#/R-GGA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Gallus gallus 2377 R-GGA-9038163 https://reactome.org/PathwayBrowser/#/R-GGA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Gallus gallus 2377 R-GGA-9725885 https://reactome.org/PathwayBrowser/#/R-GGA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Gallus gallus 2377 R-HSA-1449687 https://reactome.org/PathwayBrowser/#/R-HSA-1449687 Corticosteroids bind to CBG in blood TAS Homo sapiens 2377 R-HSA-193052 https://reactome.org/PathwayBrowser/#/R-HSA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone TAS Homo sapiens 2377 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 2377 R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 2377 R-HSA-2534359 https://reactome.org/PathwayBrowser/#/R-HSA-2534359 CatSper Channel Mediated Calcium Transport TAS Homo sapiens 2377 R-HSA-2534388 https://reactome.org/PathwayBrowser/#/R-HSA-2534388 Progesterone Activation Of CatSper TAS Homo sapiens 2377 R-HSA-5601976 https://reactome.org/PathwayBrowser/#/R-HSA-5601976 Defective CYP21A2 does not 21-hydroxylate PROG TAS Homo sapiens 2377 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 2377 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 2377 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 2377 R-HSA-9035954 https://reactome.org/PathwayBrowser/#/R-HSA-9035954 Defective CYP17A1 does not 17-hydroxylate P4 TAS Homo sapiens 2377 R-HSA-9038161 https://reactome.org/PathwayBrowser/#/R-HSA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG TAS Homo sapiens 2377 R-HSA-9038163 https://reactome.org/PathwayBrowser/#/R-HSA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators TAS Homo sapiens 2377 R-HSA-9725885 https://reactome.org/PathwayBrowser/#/R-HSA-9725885 P4 bind PGR (in the HSP90 chaperone complex) TAS Homo sapiens 2377 R-HSA-9960175 https://reactome.org/PathwayBrowser/#/R-HSA-9960175 Mammary stem cell produces hormone receptor positive luminal progenitor cell TAS Homo sapiens 2377 R-MMU-1449687 https://reactome.org/PathwayBrowser/#/R-MMU-1449687 Corticosteroids bind to CBG in blood IEA Mus musculus 2377 R-MMU-193052 https://reactome.org/PathwayBrowser/#/R-MMU-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Mus musculus 2377 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 2377 R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 2377 R-MMU-2534359 https://reactome.org/PathwayBrowser/#/R-MMU-2534359 CatSper Channel Mediated Calcium Transport IEA Mus musculus 2377 R-MMU-2534388 https://reactome.org/PathwayBrowser/#/R-MMU-2534388 Progesterone Activation Of CatSper IEA Mus musculus 2377 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 2377 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 2377 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 2377 R-MMU-9038161 https://reactome.org/PathwayBrowser/#/R-MMU-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Mus musculus 2377 R-MMU-9038163 https://reactome.org/PathwayBrowser/#/R-MMU-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Mus musculus 2377 R-MMU-9725885 https://reactome.org/PathwayBrowser/#/R-MMU-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Mus musculus 2377 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 2377 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 2377 R-PFA-9725885 https://reactome.org/PathwayBrowser/#/R-PFA-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2377 R-RNO-1449687 https://reactome.org/PathwayBrowser/#/R-RNO-1449687 Corticosteroids bind to CBG in blood IEA Rattus norvegicus 2377 R-RNO-193052 https://reactome.org/PathwayBrowser/#/R-RNO-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Rattus norvegicus 2377 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 2377 R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 2377 R-RNO-2534359 https://reactome.org/PathwayBrowser/#/R-RNO-2534359 CatSper Channel Mediated Calcium Transport IEA Rattus norvegicus 2377 R-RNO-2534388 https://reactome.org/PathwayBrowser/#/R-RNO-2534388 Progesterone Activation Of CatSper IEA Rattus norvegicus 2377 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 2377 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 2377 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 2377 R-RNO-9038161 https://reactome.org/PathwayBrowser/#/R-RNO-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Rattus norvegicus 2377 R-RNO-9038163 https://reactome.org/PathwayBrowser/#/R-RNO-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Rattus norvegicus 2377 R-RNO-9725885 https://reactome.org/PathwayBrowser/#/R-RNO-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Rattus norvegicus 2377 R-SSC-1449687 https://reactome.org/PathwayBrowser/#/R-SSC-1449687 Corticosteroids bind to CBG in blood IEA Sus scrofa 2377 R-SSC-193052 https://reactome.org/PathwayBrowser/#/R-SSC-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone IEA Sus scrofa 2377 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 2377 R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 2377 R-SSC-2534359 https://reactome.org/PathwayBrowser/#/R-SSC-2534359 CatSper Channel Mediated Calcium Transport IEA Sus scrofa 2377 R-SSC-2534388 https://reactome.org/PathwayBrowser/#/R-SSC-2534388 Progesterone Activation Of CatSper IEA Sus scrofa 2377 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 2377 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 2377 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 2377 R-SSC-9038161 https://reactome.org/PathwayBrowser/#/R-SSC-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG IEA Sus scrofa 2377 R-SSC-9038163 https://reactome.org/PathwayBrowser/#/R-SSC-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators IEA Sus scrofa 2377 R-SSC-9725885 https://reactome.org/PathwayBrowser/#/R-SSC-9725885 P4 bind PGR (in the HSP90 chaperone complex) IEA Sus scrofa 2377 R-XTR-1449687 https://reactome.org/PathwayBrowser/#/R-XTR-1449687 Corticosteroids bind to CBG in blood IEA Xenopus tropicalis 2377 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 2398 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 2398 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 2398 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 2398 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 2398 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 2398 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 2398 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 2398 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 2398 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 2398 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 2398 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 2398 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 2399 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 2399 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 2399 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 2399 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 2399 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 2399 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 2399 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 2399 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 2399 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 2399 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 2399 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 2399 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 2399 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 2399 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 2399 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 2399 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 2399 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 2399 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 2399 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 2399 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 2399 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 2399 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 2399 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 2399 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 2399 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 2399 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 2399 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 2399 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 2399 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 2399 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 2399 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 2399 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 2401 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 2401 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 2401 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 2401 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 2401 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 2401 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 2401 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 2401 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 2401 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 2401 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 2401 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 2401 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 2404 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 2404 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 2404 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 2404 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 2404 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 2404 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 2404 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 2404 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 2404 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 2404 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 2404 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 2404 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 2406 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2406 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 2406 R-BTA-9678766 https://reactome.org/PathwayBrowser/#/R-BTA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Bos taurus 2406 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2406 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2406 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 2406 R-CFA-9678766 https://reactome.org/PathwayBrowser/#/R-CFA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Canis familiaris 2406 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 2406 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2406 R-DRE-9678766 https://reactome.org/PathwayBrowser/#/R-DRE-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Danio rerio 2406 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2406 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 2406 R-GGA-9678766 https://reactome.org/PathwayBrowser/#/R-GGA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Gallus gallus 2406 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2406 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 2406 R-HSA-9678766 https://reactome.org/PathwayBrowser/#/R-HSA-9678766 CYP3A4 binds CYP3A4 inhibitors TAS Homo sapiens 2406 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2406 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 2406 R-MMU-9678766 https://reactome.org/PathwayBrowser/#/R-MMU-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Mus musculus 2406 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 2406 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2406 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 2406 R-RNO-9678766 https://reactome.org/PathwayBrowser/#/R-RNO-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Rattus norvegicus 2406 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 2406 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2406 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 2406 R-SSC-9678766 https://reactome.org/PathwayBrowser/#/R-SSC-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Sus scrofa 2406 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 2406 R-XTR-9678766 https://reactome.org/PathwayBrowser/#/R-XTR-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Xenopus tropicalis 2407 R-BTA-9678854 https://reactome.org/PathwayBrowser/#/R-BTA-9678854 S1PR1 binds S1PR1 agonists IEA Bos taurus 2407 R-BTA-9690449 https://reactome.org/PathwayBrowser/#/R-BTA-9690449 S1PR1 bind S1P IEA Bos taurus 2407 R-CFA-9678854 https://reactome.org/PathwayBrowser/#/R-CFA-9678854 S1PR1 binds S1PR1 agonists IEA Canis familiaris 2407 R-CFA-9690449 https://reactome.org/PathwayBrowser/#/R-CFA-9690449 S1PR1 bind S1P IEA Canis familiaris 2407 R-DRE-9678854 https://reactome.org/PathwayBrowser/#/R-DRE-9678854 S1PR1 binds S1PR1 agonists IEA Danio rerio 2407 R-DRE-9690449 https://reactome.org/PathwayBrowser/#/R-DRE-9690449 S1PR1 bind S1P IEA Danio rerio 2407 R-GGA-9678854 https://reactome.org/PathwayBrowser/#/R-GGA-9678854 S1PR1 binds S1PR1 agonists IEA Gallus gallus 2407 R-GGA-9690449 https://reactome.org/PathwayBrowser/#/R-GGA-9690449 S1PR1 bind S1P IEA Gallus gallus 2407 R-HSA-9678854 https://reactome.org/PathwayBrowser/#/R-HSA-9678854 S1PR1 binds S1PR1 agonists TAS Homo sapiens 2407 R-HSA-9690449 https://reactome.org/PathwayBrowser/#/R-HSA-9690449 S1PR1 bind S1P TAS Homo sapiens 2407 R-MMU-9678854 https://reactome.org/PathwayBrowser/#/R-MMU-9678854 S1PR1 binds S1PR1 agonists IEA Mus musculus 2407 R-MMU-9690449 https://reactome.org/PathwayBrowser/#/R-MMU-9690449 S1PR1 bind S1P IEA Mus musculus 2407 R-RNO-9678854 https://reactome.org/PathwayBrowser/#/R-RNO-9678854 S1PR1 binds S1PR1 agonists IEA Rattus norvegicus 2407 R-RNO-9690449 https://reactome.org/PathwayBrowser/#/R-RNO-9690449 S1PR1 bind S1P IEA Rattus norvegicus 2407 R-SSC-9678854 https://reactome.org/PathwayBrowser/#/R-SSC-9678854 S1PR1 binds S1PR1 agonists IEA Sus scrofa 2407 R-SSC-9690449 https://reactome.org/PathwayBrowser/#/R-SSC-9690449 S1PR1 bind S1P IEA Sus scrofa 2407 R-XTR-9678854 https://reactome.org/PathwayBrowser/#/R-XTR-9678854 S1PR1 binds S1PR1 agonists IEA Xenopus tropicalis 2407 R-XTR-9690449 https://reactome.org/PathwayBrowser/#/R-XTR-9690449 S1PR1 bind S1P IEA Xenopus tropicalis 2409 R-NUL-421961 https://reactome.org/PathwayBrowser/#/R-NUL-421961 Dissociation of beta-2 adrenergic receptor:Gs complex TAS Oryctolagus cuniculus 2410 R-BTA-114552 https://reactome.org/PathwayBrowser/#/R-BTA-114552 Thrombin-activated PARs activate G12/13 IEA Bos taurus 2410 R-BTA-114558 https://reactome.org/PathwayBrowser/#/R-BTA-114558 Thrombin-activated PARs activate Gq IEA Bos taurus 2410 R-BTA-170674 https://reactome.org/PathwayBrowser/#/R-BTA-170674 Dissociation of the Gi alpha:G olf complex IEA Bos taurus 2410 R-BTA-170686 https://reactome.org/PathwayBrowser/#/R-BTA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Bos taurus 2410 R-BTA-205039 https://reactome.org/PathwayBrowser/#/R-BTA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Bos taurus 2410 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 2410 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2410 R-BTA-381727 https://reactome.org/PathwayBrowser/#/R-BTA-381727 RAP1A exchanges GDP for GTP IEA Bos taurus 2410 R-BTA-392187 https://reactome.org/PathwayBrowser/#/R-BTA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Bos taurus 2410 R-BTA-392195 https://reactome.org/PathwayBrowser/#/R-BTA-392195 Gi activation by P2Y purinoceptor 12 IEA Bos taurus 2410 R-BTA-3928633 https://reactome.org/PathwayBrowser/#/R-BTA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Bos taurus 2410 R-BTA-392870 https://reactome.org/PathwayBrowser/#/R-BTA-392870 Gs activation by prostacyclin receptor IEA Bos taurus 2410 R-BTA-396996 https://reactome.org/PathwayBrowser/#/R-BTA-396996 Thrombin-activated PARs binds G-protein Gq IEA Bos taurus 2410 R-BTA-416530 https://reactome.org/PathwayBrowser/#/R-BTA-416530 FFAR1:FFAR1 ligands activate Gq IEA Bos taurus 2410 R-BTA-416546 https://reactome.org/PathwayBrowser/#/R-BTA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Bos taurus 2410 R-BTA-416588 https://reactome.org/PathwayBrowser/#/R-BTA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Bos taurus 2410 R-BTA-418574 https://reactome.org/PathwayBrowser/#/R-BTA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Bos taurus 2410 R-BTA-418582 https://reactome.org/PathwayBrowser/#/R-BTA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Bos taurus 2410 R-BTA-419166 https://reactome.org/PathwayBrowser/#/R-BTA-419166 GEFs activate RhoA,B,C IEA Bos taurus 2410 R-BTA-420883 https://reactome.org/PathwayBrowser/#/R-BTA-420883 Opsins act as GEFs for G alpha-t IEA Bos taurus 2410 R-BTA-428749 https://reactome.org/PathwayBrowser/#/R-BTA-428749 Activated TP receptor binds G-proten Gq IEA Bos taurus 2410 R-BTA-428750 https://reactome.org/PathwayBrowser/#/R-BTA-428750 Gq activation by TP receptor IEA Bos taurus 2410 R-BTA-428909 https://reactome.org/PathwayBrowser/#/R-BTA-428909 Activated TP receptor binds G-protein G13 IEA Bos taurus 2410 R-BTA-428917 https://reactome.org/PathwayBrowser/#/R-BTA-428917 G13 activation by TP receptor IEA Bos taurus 2410 R-BTA-481009 https://reactome.org/PathwayBrowser/#/R-BTA-481009 Exocytosis of platelet dense granule content IEA Bos taurus 2410 R-BTA-5638006 https://reactome.org/PathwayBrowser/#/R-BTA-5638006 ARL3 hydrolyzes GTP IEA Bos taurus 2410 R-BTA-5638016 https://reactome.org/PathwayBrowser/#/R-BTA-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Bos taurus 2410 R-BTA-749446 https://reactome.org/PathwayBrowser/#/R-BTA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Bos taurus 2410 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 2410 R-BTA-749453 https://reactome.org/PathwayBrowser/#/R-BTA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Bos taurus 2410 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2410 R-BTA-750988 https://reactome.org/PathwayBrowser/#/R-BTA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Bos taurus 2410 R-BTA-750993 https://reactome.org/PathwayBrowser/#/R-BTA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Bos taurus 2410 R-BTA-751001 https://reactome.org/PathwayBrowser/#/R-BTA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Bos taurus 2410 R-BTA-751027 https://reactome.org/PathwayBrowser/#/R-BTA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Bos taurus 2410 R-BTA-751029 https://reactome.org/PathwayBrowser/#/R-BTA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Bos taurus 2410 R-BTA-751039 https://reactome.org/PathwayBrowser/#/R-BTA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Bos taurus 2410 R-BTA-77081 https://reactome.org/PathwayBrowser/#/R-BTA-77081 Formation of the CE:GMP intermediate complex IEA Bos taurus 2410 R-BTA-8854329 https://reactome.org/PathwayBrowser/#/R-BTA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Bos taurus 2410 R-BTA-8854604 https://reactome.org/PathwayBrowser/#/R-BTA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Bos taurus 2410 R-BTA-8982012 https://reactome.org/PathwayBrowser/#/R-BTA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Bos taurus 2410 R-BTA-8982018 https://reactome.org/PathwayBrowser/#/R-BTA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Bos taurus 2410 R-BTA-8982026 https://reactome.org/PathwayBrowser/#/R-BTA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Bos taurus 2410 R-BTA-8982637 https://reactome.org/PathwayBrowser/#/R-BTA-8982637 Opsins binds G alpha-t IEA Bos taurus 2410 R-BTA-9021596 https://reactome.org/PathwayBrowser/#/R-BTA-9021596 Membrane estrogen receptors bind SRC IEA Bos taurus 2410 R-BTA-9021600 https://reactome.org/PathwayBrowser/#/R-BTA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Bos taurus 2410 R-BTA-9021601 https://reactome.org/PathwayBrowser/#/R-BTA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Bos taurus 2410 R-BTA-9935449 https://reactome.org/PathwayBrowser/#/R-BTA-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Bos taurus 2410 R-BTA-9935469 https://reactome.org/PathwayBrowser/#/R-BTA-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Bos taurus 2410 R-CEL-114552 https://reactome.org/PathwayBrowser/#/R-CEL-114552 Thrombin-activated PARs activate G12/13 IEA Caenorhabditis elegans 2410 R-CEL-114558 https://reactome.org/PathwayBrowser/#/R-CEL-114558 Thrombin-activated PARs activate Gq IEA Caenorhabditis elegans 2410 R-CEL-170674 https://reactome.org/PathwayBrowser/#/R-CEL-170674 Dissociation of the Gi alpha:G olf complex IEA Caenorhabditis elegans 2410 R-CEL-170686 https://reactome.org/PathwayBrowser/#/R-CEL-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Caenorhabditis elegans 2410 R-CEL-205039 https://reactome.org/PathwayBrowser/#/R-CEL-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Caenorhabditis elegans 2410 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 2410 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 2410 R-CEL-381727 https://reactome.org/PathwayBrowser/#/R-CEL-381727 RAP1A exchanges GDP for GTP IEA Caenorhabditis elegans 2410 R-CEL-392195 https://reactome.org/PathwayBrowser/#/R-CEL-392195 Gi activation by P2Y purinoceptor 12 IEA Caenorhabditis elegans 2410 R-CEL-3928612 https://reactome.org/PathwayBrowser/#/R-CEL-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Caenorhabditis elegans 2410 R-CEL-3928633 https://reactome.org/PathwayBrowser/#/R-CEL-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Caenorhabditis elegans 2410 R-CEL-396996 https://reactome.org/PathwayBrowser/#/R-CEL-396996 Thrombin-activated PARs binds G-protein Gq IEA Caenorhabditis elegans 2410 R-CEL-416546 https://reactome.org/PathwayBrowser/#/R-CEL-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Caenorhabditis elegans 2410 R-CEL-416588 https://reactome.org/PathwayBrowser/#/R-CEL-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Caenorhabditis elegans 2410 R-CEL-418574 https://reactome.org/PathwayBrowser/#/R-CEL-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Caenorhabditis elegans 2410 R-CEL-418582 https://reactome.org/PathwayBrowser/#/R-CEL-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Caenorhabditis elegans 2410 R-CEL-419166 https://reactome.org/PathwayBrowser/#/R-CEL-419166 GEFs activate RhoA,B,C IEA Caenorhabditis elegans 2410 R-CEL-420883 https://reactome.org/PathwayBrowser/#/R-CEL-420883 Opsins act as GEFs for G alpha-t IEA Caenorhabditis elegans 2410 R-CEL-428750 https://reactome.org/PathwayBrowser/#/R-CEL-428750 Gq activation by TP receptor IEA Caenorhabditis elegans 2410 R-CEL-428917 https://reactome.org/PathwayBrowser/#/R-CEL-428917 G13 activation by TP receptor IEA Caenorhabditis elegans 2410 R-CEL-481009 https://reactome.org/PathwayBrowser/#/R-CEL-481009 Exocytosis of platelet dense granule content IEA Caenorhabditis elegans 2410 R-CEL-5638006 https://reactome.org/PathwayBrowser/#/R-CEL-5638006 ARL3 hydrolyzes GTP IEA Caenorhabditis elegans 2410 R-CEL-5638016 https://reactome.org/PathwayBrowser/#/R-CEL-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Caenorhabditis elegans 2410 R-CEL-749446 https://reactome.org/PathwayBrowser/#/R-CEL-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Caenorhabditis elegans 2410 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 2410 R-CEL-749453 https://reactome.org/PathwayBrowser/#/R-CEL-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Caenorhabditis elegans 2410 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 2410 R-CEL-750988 https://reactome.org/PathwayBrowser/#/R-CEL-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Caenorhabditis elegans 2410 R-CEL-750993 https://reactome.org/PathwayBrowser/#/R-CEL-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Caenorhabditis elegans 2410 R-CEL-751001 https://reactome.org/PathwayBrowser/#/R-CEL-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Caenorhabditis elegans 2410 R-CEL-751027 https://reactome.org/PathwayBrowser/#/R-CEL-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Caenorhabditis elegans 2410 R-CEL-751029 https://reactome.org/PathwayBrowser/#/R-CEL-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Caenorhabditis elegans 2410 R-CEL-751039 https://reactome.org/PathwayBrowser/#/R-CEL-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Caenorhabditis elegans 2410 R-CEL-77081 https://reactome.org/PathwayBrowser/#/R-CEL-77081 Formation of the CE:GMP intermediate complex IEA Caenorhabditis elegans 2410 R-CEL-8854329 https://reactome.org/PathwayBrowser/#/R-CEL-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 2410 R-CEL-8982012 https://reactome.org/PathwayBrowser/#/R-CEL-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Caenorhabditis elegans 2410 R-CEL-8982018 https://reactome.org/PathwayBrowser/#/R-CEL-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Caenorhabditis elegans 2410 R-CEL-8982026 https://reactome.org/PathwayBrowser/#/R-CEL-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Caenorhabditis elegans 2410 R-CFA-114552 https://reactome.org/PathwayBrowser/#/R-CFA-114552 Thrombin-activated PARs activate G12/13 IEA Canis familiaris 2410 R-CFA-114558 https://reactome.org/PathwayBrowser/#/R-CFA-114558 Thrombin-activated PARs activate Gq IEA Canis familiaris 2410 R-CFA-170674 https://reactome.org/PathwayBrowser/#/R-CFA-170674 Dissociation of the Gi alpha:G olf complex IEA Canis familiaris 2410 R-CFA-170686 https://reactome.org/PathwayBrowser/#/R-CFA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Canis familiaris 2410 R-CFA-205039 https://reactome.org/PathwayBrowser/#/R-CFA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Canis familiaris 2410 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 2410 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2410 R-CFA-381727 https://reactome.org/PathwayBrowser/#/R-CFA-381727 RAP1A exchanges GDP for GTP IEA Canis familiaris 2410 R-CFA-392187 https://reactome.org/PathwayBrowser/#/R-CFA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Canis familiaris 2410 R-CFA-392195 https://reactome.org/PathwayBrowser/#/R-CFA-392195 Gi activation by P2Y purinoceptor 12 IEA Canis familiaris 2410 R-CFA-3928612 https://reactome.org/PathwayBrowser/#/R-CFA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Canis familiaris 2410 R-CFA-3928633 https://reactome.org/PathwayBrowser/#/R-CFA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Canis familiaris 2410 R-CFA-392870 https://reactome.org/PathwayBrowser/#/R-CFA-392870 Gs activation by prostacyclin receptor IEA Canis familiaris 2410 R-CFA-396996 https://reactome.org/PathwayBrowser/#/R-CFA-396996 Thrombin-activated PARs binds G-protein Gq IEA Canis familiaris 2410 R-CFA-416530 https://reactome.org/PathwayBrowser/#/R-CFA-416530 FFAR1:FFAR1 ligands activate Gq IEA Canis familiaris 2410 R-CFA-416546 https://reactome.org/PathwayBrowser/#/R-CFA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Canis familiaris 2410 R-CFA-416588 https://reactome.org/PathwayBrowser/#/R-CFA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Canis familiaris 2410 R-CFA-418574 https://reactome.org/PathwayBrowser/#/R-CFA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Canis familiaris 2410 R-CFA-418582 https://reactome.org/PathwayBrowser/#/R-CFA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Canis familiaris 2410 R-CFA-419166 https://reactome.org/PathwayBrowser/#/R-CFA-419166 GEFs activate RhoA,B,C IEA Canis familiaris 2410 R-CFA-420883 https://reactome.org/PathwayBrowser/#/R-CFA-420883 Opsins act as GEFs for G alpha-t IEA Canis familiaris 2410 R-CFA-428749 https://reactome.org/PathwayBrowser/#/R-CFA-428749 Activated TP receptor binds G-proten Gq IEA Canis familiaris 2410 R-CFA-428750 https://reactome.org/PathwayBrowser/#/R-CFA-428750 Gq activation by TP receptor IEA Canis familiaris 2410 R-CFA-428909 https://reactome.org/PathwayBrowser/#/R-CFA-428909 Activated TP receptor binds G-protein G13 IEA Canis familiaris 2410 R-CFA-428917 https://reactome.org/PathwayBrowser/#/R-CFA-428917 G13 activation by TP receptor IEA Canis familiaris 2410 R-CFA-481009 https://reactome.org/PathwayBrowser/#/R-CFA-481009 Exocytosis of platelet dense granule content IEA Canis familiaris 2410 R-CFA-5638006 https://reactome.org/PathwayBrowser/#/R-CFA-5638006 ARL3 hydrolyzes GTP IEA Canis familiaris 2410 R-CFA-5638016 https://reactome.org/PathwayBrowser/#/R-CFA-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Canis familiaris 2410 R-CFA-749446 https://reactome.org/PathwayBrowser/#/R-CFA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Canis familiaris 2410 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 2410 R-CFA-749453 https://reactome.org/PathwayBrowser/#/R-CFA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Canis familiaris 2410 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2410 R-CFA-750988 https://reactome.org/PathwayBrowser/#/R-CFA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Canis familiaris 2410 R-CFA-750993 https://reactome.org/PathwayBrowser/#/R-CFA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Canis familiaris 2410 R-CFA-751001 https://reactome.org/PathwayBrowser/#/R-CFA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Canis familiaris 2410 R-CFA-751027 https://reactome.org/PathwayBrowser/#/R-CFA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Canis familiaris 2410 R-CFA-751029 https://reactome.org/PathwayBrowser/#/R-CFA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Canis familiaris 2410 R-CFA-751039 https://reactome.org/PathwayBrowser/#/R-CFA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Canis familiaris 2410 R-CFA-77081 https://reactome.org/PathwayBrowser/#/R-CFA-77081 Formation of the CE:GMP intermediate complex IEA Canis familiaris 2410 R-CFA-8854329 https://reactome.org/PathwayBrowser/#/R-CFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 2410 R-CFA-8854604 https://reactome.org/PathwayBrowser/#/R-CFA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Canis familiaris 2410 R-CFA-8982012 https://reactome.org/PathwayBrowser/#/R-CFA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Canis familiaris 2410 R-CFA-8982018 https://reactome.org/PathwayBrowser/#/R-CFA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Canis familiaris 2410 R-CFA-8982026 https://reactome.org/PathwayBrowser/#/R-CFA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Canis familiaris 2410 R-CFA-8982637 https://reactome.org/PathwayBrowser/#/R-CFA-8982637 Opsins binds G alpha-t IEA Canis familiaris 2410 R-CFA-9021596 https://reactome.org/PathwayBrowser/#/R-CFA-9021596 Membrane estrogen receptors bind SRC IEA Canis familiaris 2410 R-CFA-9021600 https://reactome.org/PathwayBrowser/#/R-CFA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Canis familiaris 2410 R-CFA-9021601 https://reactome.org/PathwayBrowser/#/R-CFA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Canis familiaris 2410 R-CFA-9935449 https://reactome.org/PathwayBrowser/#/R-CFA-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Canis familiaris 2410 R-CFA-9935469 https://reactome.org/PathwayBrowser/#/R-CFA-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Canis familiaris 2410 R-DDI-170674 https://reactome.org/PathwayBrowser/#/R-DDI-170674 Dissociation of the Gi alpha:G olf complex IEA Dictyostelium discoideum 2410 R-DDI-170686 https://reactome.org/PathwayBrowser/#/R-DDI-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Dictyostelium discoideum 2410 R-DDI-205039 https://reactome.org/PathwayBrowser/#/R-DDI-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Dictyostelium discoideum 2410 R-DDI-380073 https://reactome.org/PathwayBrowser/#/R-DDI-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Dictyostelium discoideum 2410 R-DDI-381727 https://reactome.org/PathwayBrowser/#/R-DDI-381727 RAP1A exchanges GDP for GTP IEA Dictyostelium discoideum 2410 R-DDI-418574 https://reactome.org/PathwayBrowser/#/R-DDI-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Dictyostelium discoideum 2410 R-DDI-418582 https://reactome.org/PathwayBrowser/#/R-DDI-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Dictyostelium discoideum 2410 R-DDI-481009 https://reactome.org/PathwayBrowser/#/R-DDI-481009 Exocytosis of platelet dense granule content IEA Dictyostelium discoideum 2410 R-DDI-77081 https://reactome.org/PathwayBrowser/#/R-DDI-77081 Formation of the CE:GMP intermediate complex IEA Dictyostelium discoideum 2410 R-DDI-8854329 https://reactome.org/PathwayBrowser/#/R-DDI-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 2410 R-DDI-8854604 https://reactome.org/PathwayBrowser/#/R-DDI-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Dictyostelium discoideum 2410 R-DDI-8982012 https://reactome.org/PathwayBrowser/#/R-DDI-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Dictyostelium discoideum 2410 R-DDI-8982018 https://reactome.org/PathwayBrowser/#/R-DDI-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Dictyostelium discoideum 2410 R-DDI-8982026 https://reactome.org/PathwayBrowser/#/R-DDI-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Dictyostelium discoideum 2410 R-DME-170674 https://reactome.org/PathwayBrowser/#/R-DME-170674 Dissociation of the Gi alpha:G olf complex IEA Drosophila melanogaster 2410 R-DME-170686 https://reactome.org/PathwayBrowser/#/R-DME-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Drosophila melanogaster 2410 R-DME-205039 https://reactome.org/PathwayBrowser/#/R-DME-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Drosophila melanogaster 2410 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 2410 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 2410 R-DME-381727 https://reactome.org/PathwayBrowser/#/R-DME-381727 RAP1A exchanges GDP for GTP IEA Drosophila melanogaster 2410 R-DME-392195 https://reactome.org/PathwayBrowser/#/R-DME-392195 Gi activation by P2Y purinoceptor 12 IEA Drosophila melanogaster 2410 R-DME-3928612 https://reactome.org/PathwayBrowser/#/R-DME-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Drosophila melanogaster 2410 R-DME-3928633 https://reactome.org/PathwayBrowser/#/R-DME-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Drosophila melanogaster 2410 R-DME-392870 https://reactome.org/PathwayBrowser/#/R-DME-392870 Gs activation by prostacyclin receptor IEA Drosophila melanogaster 2410 R-DME-416588 https://reactome.org/PathwayBrowser/#/R-DME-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Drosophila melanogaster 2410 R-DME-418574 https://reactome.org/PathwayBrowser/#/R-DME-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Drosophila melanogaster 2410 R-DME-418582 https://reactome.org/PathwayBrowser/#/R-DME-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Drosophila melanogaster 2410 R-DME-419166 https://reactome.org/PathwayBrowser/#/R-DME-419166 GEFs activate RhoA,B,C IEA Drosophila melanogaster 2410 R-DME-428749 https://reactome.org/PathwayBrowser/#/R-DME-428749 Activated TP receptor binds G-proten Gq IEA Drosophila melanogaster 2410 R-DME-428750 https://reactome.org/PathwayBrowser/#/R-DME-428750 Gq activation by TP receptor IEA Drosophila melanogaster 2410 R-DME-428909 https://reactome.org/PathwayBrowser/#/R-DME-428909 Activated TP receptor binds G-protein G13 IEA Drosophila melanogaster 2410 R-DME-428917 https://reactome.org/PathwayBrowser/#/R-DME-428917 G13 activation by TP receptor IEA Drosophila melanogaster 2410 R-DME-481009 https://reactome.org/PathwayBrowser/#/R-DME-481009 Exocytosis of platelet dense granule content IEA Drosophila melanogaster 2410 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 2410 R-DME-749453 https://reactome.org/PathwayBrowser/#/R-DME-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Drosophila melanogaster 2410 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 2410 R-DME-750993 https://reactome.org/PathwayBrowser/#/R-DME-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Drosophila melanogaster 2410 R-DME-751001 https://reactome.org/PathwayBrowser/#/R-DME-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Drosophila melanogaster 2410 R-DME-751027 https://reactome.org/PathwayBrowser/#/R-DME-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Drosophila melanogaster 2410 R-DME-751029 https://reactome.org/PathwayBrowser/#/R-DME-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Drosophila melanogaster 2410 R-DME-751039 https://reactome.org/PathwayBrowser/#/R-DME-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Drosophila melanogaster 2410 R-DME-77081 https://reactome.org/PathwayBrowser/#/R-DME-77081 Formation of the CE:GMP intermediate complex IEA Drosophila melanogaster 2410 R-DME-8854329 https://reactome.org/PathwayBrowser/#/R-DME-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 2410 R-DME-8854604 https://reactome.org/PathwayBrowser/#/R-DME-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Drosophila melanogaster 2410 R-DME-8982012 https://reactome.org/PathwayBrowser/#/R-DME-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Drosophila melanogaster 2410 R-DME-8982026 https://reactome.org/PathwayBrowser/#/R-DME-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Drosophila melanogaster 2410 R-DME-9021596 https://reactome.org/PathwayBrowser/#/R-DME-9021596 Membrane estrogen receptors bind SRC IEA Drosophila melanogaster 2410 R-DME-9021600 https://reactome.org/PathwayBrowser/#/R-DME-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Drosophila melanogaster 2410 R-DME-9021601 https://reactome.org/PathwayBrowser/#/R-DME-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Drosophila melanogaster 2410 R-DRE-114558 https://reactome.org/PathwayBrowser/#/R-DRE-114558 Thrombin-activated PARs activate Gq IEA Danio rerio 2410 R-DRE-170674 https://reactome.org/PathwayBrowser/#/R-DRE-170674 Dissociation of the Gi alpha:G olf complex IEA Danio rerio 2410 R-DRE-170686 https://reactome.org/PathwayBrowser/#/R-DRE-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Danio rerio 2410 R-DRE-205039 https://reactome.org/PathwayBrowser/#/R-DRE-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Danio rerio 2410 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 2410 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2410 R-DRE-392195 https://reactome.org/PathwayBrowser/#/R-DRE-392195 Gi activation by P2Y purinoceptor 12 IEA Danio rerio 2410 R-DRE-416546 https://reactome.org/PathwayBrowser/#/R-DRE-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Danio rerio 2410 R-DRE-416588 https://reactome.org/PathwayBrowser/#/R-DRE-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Danio rerio 2410 R-DRE-418574 https://reactome.org/PathwayBrowser/#/R-DRE-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Danio rerio 2410 R-DRE-418582 https://reactome.org/PathwayBrowser/#/R-DRE-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Danio rerio 2410 R-DRE-419166 https://reactome.org/PathwayBrowser/#/R-DRE-419166 GEFs activate RhoA,B,C IEA Danio rerio 2410 R-DRE-420883 https://reactome.org/PathwayBrowser/#/R-DRE-420883 Opsins act as GEFs for G alpha-t IEA Danio rerio 2410 R-DRE-428750 https://reactome.org/PathwayBrowser/#/R-DRE-428750 Gq activation by TP receptor IEA Danio rerio 2410 R-DRE-428917 https://reactome.org/PathwayBrowser/#/R-DRE-428917 G13 activation by TP receptor IEA Danio rerio 2410 R-DRE-481009 https://reactome.org/PathwayBrowser/#/R-DRE-481009 Exocytosis of platelet dense granule content IEA Danio rerio 2410 R-DRE-5638006 https://reactome.org/PathwayBrowser/#/R-DRE-5638006 ARL3 hydrolyzes GTP IEA Danio rerio 2410 R-DRE-5638016 https://reactome.org/PathwayBrowser/#/R-DRE-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Danio rerio 2410 R-DRE-77081 https://reactome.org/PathwayBrowser/#/R-DRE-77081 Formation of the CE:GMP intermediate complex IEA Danio rerio 2410 R-DRE-8854329 https://reactome.org/PathwayBrowser/#/R-DRE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Danio rerio 2410 R-DRE-8854604 https://reactome.org/PathwayBrowser/#/R-DRE-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Danio rerio 2410 R-DRE-8982012 https://reactome.org/PathwayBrowser/#/R-DRE-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Danio rerio 2410 R-DRE-8982026 https://reactome.org/PathwayBrowser/#/R-DRE-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Danio rerio 2410 R-DRE-9021596 https://reactome.org/PathwayBrowser/#/R-DRE-9021596 Membrane estrogen receptors bind SRC IEA Danio rerio 2410 R-GGA-114552 https://reactome.org/PathwayBrowser/#/R-GGA-114552 Thrombin-activated PARs activate G12/13 IEA Gallus gallus 2410 R-GGA-114558 https://reactome.org/PathwayBrowser/#/R-GGA-114558 Thrombin-activated PARs activate Gq IEA Gallus gallus 2410 R-GGA-170674 https://reactome.org/PathwayBrowser/#/R-GGA-170674 Dissociation of the Gi alpha:G olf complex IEA Gallus gallus 2410 R-GGA-170686 https://reactome.org/PathwayBrowser/#/R-GGA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Gallus gallus 2410 R-GGA-205039 https://reactome.org/PathwayBrowser/#/R-GGA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Gallus gallus 2410 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 2410 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2410 R-GGA-381727 https://reactome.org/PathwayBrowser/#/R-GGA-381727 RAP1A exchanges GDP for GTP IEA Gallus gallus 2410 R-GGA-392195 https://reactome.org/PathwayBrowser/#/R-GGA-392195 Gi activation by P2Y purinoceptor 12 IEA Gallus gallus 2410 R-GGA-3928612 https://reactome.org/PathwayBrowser/#/R-GGA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Gallus gallus 2410 R-GGA-3928633 https://reactome.org/PathwayBrowser/#/R-GGA-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Gallus gallus 2410 R-GGA-396996 https://reactome.org/PathwayBrowser/#/R-GGA-396996 Thrombin-activated PARs binds G-protein Gq IEA Gallus gallus 2410 R-GGA-416588 https://reactome.org/PathwayBrowser/#/R-GGA-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Gallus gallus 2410 R-GGA-418574 https://reactome.org/PathwayBrowser/#/R-GGA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Gallus gallus 2410 R-GGA-418582 https://reactome.org/PathwayBrowser/#/R-GGA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Gallus gallus 2410 R-GGA-419166 https://reactome.org/PathwayBrowser/#/R-GGA-419166 GEFs activate RhoA,B,C IEA Gallus gallus 2410 R-GGA-420883 https://reactome.org/PathwayBrowser/#/R-GGA-420883 Opsins act as GEFs for G alpha-t IEA Gallus gallus 2410 R-GGA-428749 https://reactome.org/PathwayBrowser/#/R-GGA-428749 Activated TP receptor binds G-proten Gq IEA Gallus gallus 2410 R-GGA-428750 https://reactome.org/PathwayBrowser/#/R-GGA-428750 Gq activation by TP receptor IEA Gallus gallus 2410 R-GGA-428909 https://reactome.org/PathwayBrowser/#/R-GGA-428909 Activated TP receptor binds G-protein G13 IEA Gallus gallus 2410 R-GGA-428917 https://reactome.org/PathwayBrowser/#/R-GGA-428917 G13 activation by TP receptor IEA Gallus gallus 2410 R-GGA-481009 https://reactome.org/PathwayBrowser/#/R-GGA-481009 Exocytosis of platelet dense granule content IEA Gallus gallus 2410 R-GGA-5638006 https://reactome.org/PathwayBrowser/#/R-GGA-5638006 ARL3 hydrolyzes GTP IEA Gallus gallus 2410 R-GGA-5638016 https://reactome.org/PathwayBrowser/#/R-GGA-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Gallus gallus 2410 R-GGA-749446 https://reactome.org/PathwayBrowser/#/R-GGA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Gallus gallus 2410 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 2410 R-GGA-749453 https://reactome.org/PathwayBrowser/#/R-GGA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Gallus gallus 2410 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2410 R-GGA-750988 https://reactome.org/PathwayBrowser/#/R-GGA-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Gallus gallus 2410 R-GGA-750993 https://reactome.org/PathwayBrowser/#/R-GGA-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Gallus gallus 2410 R-GGA-751001 https://reactome.org/PathwayBrowser/#/R-GGA-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Gallus gallus 2410 R-GGA-751027 https://reactome.org/PathwayBrowser/#/R-GGA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Gallus gallus 2410 R-GGA-751029 https://reactome.org/PathwayBrowser/#/R-GGA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Gallus gallus 2410 R-GGA-751039 https://reactome.org/PathwayBrowser/#/R-GGA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Gallus gallus 2410 R-GGA-77081 https://reactome.org/PathwayBrowser/#/R-GGA-77081 Formation of the CE:GMP intermediate complex IEA Gallus gallus 2410 R-GGA-8854329 https://reactome.org/PathwayBrowser/#/R-GGA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 2410 R-GGA-8854604 https://reactome.org/PathwayBrowser/#/R-GGA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Gallus gallus 2410 R-GGA-8982012 https://reactome.org/PathwayBrowser/#/R-GGA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Gallus gallus 2410 R-GGA-8982018 https://reactome.org/PathwayBrowser/#/R-GGA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Gallus gallus 2410 R-GGA-8982026 https://reactome.org/PathwayBrowser/#/R-GGA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Gallus gallus 2410 R-GGA-8982637 https://reactome.org/PathwayBrowser/#/R-GGA-8982637 Opsins binds G alpha-t IEA Gallus gallus 2410 R-GGA-9021596 https://reactome.org/PathwayBrowser/#/R-GGA-9021596 Membrane estrogen receptors bind SRC IEA Gallus gallus 2410 R-GGA-9021600 https://reactome.org/PathwayBrowser/#/R-GGA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Gallus gallus 2410 R-GGA-9021601 https://reactome.org/PathwayBrowser/#/R-GGA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Gallus gallus 2410 R-GGA-9935449 https://reactome.org/PathwayBrowser/#/R-GGA-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Gallus gallus 2410 R-GGA-9935469 https://reactome.org/PathwayBrowser/#/R-GGA-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Gallus gallus 2410 R-HSA-114552 https://reactome.org/PathwayBrowser/#/R-HSA-114552 Thrombin-activated PARs activate G12/13 TAS Homo sapiens 2410 R-HSA-114558 https://reactome.org/PathwayBrowser/#/R-HSA-114558 Thrombin-activated PARs activate Gq TAS Homo sapiens 2410 R-HSA-1458485 https://reactome.org/PathwayBrowser/#/R-HSA-1458485 RALA hydrolyzes GTP IEA Homo sapiens 2410 R-HSA-170674 https://reactome.org/PathwayBrowser/#/R-HSA-170674 Dissociation of the Gi alpha:G olf complex TAS Homo sapiens 2410 R-HSA-170686 https://reactome.org/PathwayBrowser/#/R-HSA-170686 Adenylate cyclase increases the GTPase activity of Gi alpha TAS Homo sapiens 2410 R-HSA-180687 https://reactome.org/PathwayBrowser/#/R-HSA-180687 Conversion of Ran-GDP to Ran-GTP TAS Homo sapiens 2410 R-HSA-1912349 https://reactome.org/PathwayBrowser/#/R-HSA-1912349 Fucosylation of Pre-NOTCH by POFUT1 IEA Homo sapiens 2410 R-HSA-205039 https://reactome.org/PathwayBrowser/#/R-HSA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor TAS Homo sapiens 2410 R-HSA-2255342 https://reactome.org/PathwayBrowser/#/R-HSA-2255342 RALA exchanges GDP for GTP IEA Homo sapiens 2410 R-HSA-2255343 https://reactome.org/PathwayBrowser/#/R-HSA-2255343 RAB8A,10,13,14 exchange GDP for GTP IEA Homo sapiens 2410 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 2410 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2410 R-HSA-381727 https://reactome.org/PathwayBrowser/#/R-HSA-381727 RAP1A exchanges GDP for GTP TAS Homo sapiens 2410 R-HSA-392133 https://reactome.org/PathwayBrowser/#/R-HSA-392133 G alpha (z) auto-inactivates by hydrolysing GTP to GDP IEA Homo sapiens 2410 R-HSA-392187 https://reactome.org/PathwayBrowser/#/R-HSA-392187 Activated P2Y purinoceptor 12 binds G-protein Gi TAS Homo sapiens 2410 R-HSA-392195 https://reactome.org/PathwayBrowser/#/R-HSA-392195 Gi activation by P2Y purinoceptor 12 TAS Homo sapiens 2410 R-HSA-392212 https://reactome.org/PathwayBrowser/#/R-HSA-392212 G alpha (i) auto-inactivates by hydrolysing GTP to GDP IEA Homo sapiens 2410 R-HSA-3928612 https://reactome.org/PathwayBrowser/#/R-HSA-3928612 KALRN exchanges GTP for GDP on RAC1, activating it TAS Homo sapiens 2410 R-HSA-3928633 https://reactome.org/PathwayBrowser/#/R-HSA-3928633 bPIX exchanges GTP for GDP on RAC, activating it TAS Homo sapiens 2410 R-HSA-392870 https://reactome.org/PathwayBrowser/#/R-HSA-392870 Gs activation by prostacyclin receptor TAS Homo sapiens 2410 R-HSA-396941 https://reactome.org/PathwayBrowser/#/R-HSA-396941 Thrombin-activated PARs binds G-protein G12/13 IEA Homo sapiens 2410 R-HSA-396996 https://reactome.org/PathwayBrowser/#/R-HSA-396996 Thrombin-activated PARs binds G-protein Gq TAS Homo sapiens 2410 R-HSA-399935 https://reactome.org/PathwayBrowser/#/R-HSA-399935 Inactivation of R-Ras by Sema3A-Plexin-A GAP activity IEA Homo sapiens 2410 R-HSA-399995 https://reactome.org/PathwayBrowser/#/R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq IEA Homo sapiens 2410 R-HSA-416530 https://reactome.org/PathwayBrowser/#/R-HSA-416530 FFAR1:FFAR1 ligands activate Gq TAS Homo sapiens 2410 R-HSA-416546 https://reactome.org/PathwayBrowser/#/R-HSA-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity TAS Homo sapiens 2410 R-HSA-416588 https://reactome.org/PathwayBrowser/#/R-HSA-416588 Activation of Rho by LARG and PDZ-RhoGEF TAS Homo sapiens 2410 R-HSA-418574 https://reactome.org/PathwayBrowser/#/R-HSA-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 2410 R-HSA-418579 https://reactome.org/PathwayBrowser/#/R-HSA-418579 Gq activation by P2Y purinoceptor 1 IEA Homo sapiens 2410 R-HSA-418581 https://reactome.org/PathwayBrowser/#/R-HSA-418581 Activated P2Y purinoceptor 1 binds G-protein Gq IEA Homo sapiens 2410 R-HSA-418582 https://reactome.org/PathwayBrowser/#/R-HSA-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP TAS Homo sapiens 2410 R-HSA-419166 https://reactome.org/PathwayBrowser/#/R-HSA-419166 GEFs activate RhoA,B,C TAS Homo sapiens 2410 R-HSA-420883 https://reactome.org/PathwayBrowser/#/R-HSA-420883 Opsins act as GEFs for G alpha-t TAS Homo sapiens 2410 R-HSA-428749 https://reactome.org/PathwayBrowser/#/R-HSA-428749 Activated TP receptor binds G-proten Gq TAS Homo sapiens 2410 R-HSA-428750 https://reactome.org/PathwayBrowser/#/R-HSA-428750 Gq activation by TP receptor TAS Homo sapiens 2410 R-HSA-428909 https://reactome.org/PathwayBrowser/#/R-HSA-428909 Activated TP receptor binds G-protein G13 TAS Homo sapiens 2410 R-HSA-428917 https://reactome.org/PathwayBrowser/#/R-HSA-428917 G13 activation by TP receptor TAS Homo sapiens 2410 R-HSA-481009 https://reactome.org/PathwayBrowser/#/R-HSA-481009 Exocytosis of platelet dense granule content TAS Homo sapiens 2410 R-HSA-5218829 https://reactome.org/PathwayBrowser/#/R-HSA-5218829 VEGF induces CDC42 activation by unknown mechanism TAS Homo sapiens 2410 R-HSA-5638006 https://reactome.org/PathwayBrowser/#/R-HSA-5638006 ARL3 hydrolyzes GTP TAS Homo sapiens 2410 R-HSA-5638016 https://reactome.org/PathwayBrowser/#/R-HSA-5638016 RP2:ARL3:GDP:UNC119B dissociates TAS Homo sapiens 2410 R-HSA-749446 https://reactome.org/PathwayBrowser/#/R-HSA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz TAS Homo sapiens 2410 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 2410 R-HSA-749453 https://reactome.org/PathwayBrowser/#/R-HSA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz TAS Homo sapiens 2410 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2410 R-HSA-750988 https://reactome.org/PathwayBrowser/#/R-HSA-750988 Inactive G alpha (z) reassociates with G beta:gamma TAS Homo sapiens 2410 R-HSA-750993 https://reactome.org/PathwayBrowser/#/R-HSA-750993 Inactive G alpha (q) reassociates with G beta:gamma TAS Homo sapiens 2410 R-HSA-751001 https://reactome.org/PathwayBrowser/#/R-HSA-751001 Inactive G alpha (i) reassociates with G beta:gamma TAS Homo sapiens 2410 R-HSA-751027 https://reactome.org/PathwayBrowser/#/R-HSA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 TAS Homo sapiens 2410 R-HSA-751029 https://reactome.org/PathwayBrowser/#/R-HSA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 TAS Homo sapiens 2410 R-HSA-751039 https://reactome.org/PathwayBrowser/#/R-HSA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma TAS Homo sapiens 2410 R-HSA-77081 https://reactome.org/PathwayBrowser/#/R-HSA-77081 Formation of the CE:GMP intermediate complex TAS Homo sapiens 2410 R-HSA-8854329 https://reactome.org/PathwayBrowser/#/R-HSA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 2410 R-HSA-8854604 https://reactome.org/PathwayBrowser/#/R-HSA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A TAS Homo sapiens 2410 R-HSA-8982012 https://reactome.org/PathwayBrowser/#/R-HSA-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 TAS Homo sapiens 2410 R-HSA-8982018 https://reactome.org/PathwayBrowser/#/R-HSA-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) TAS Homo sapiens 2410 R-HSA-8982026 https://reactome.org/PathwayBrowser/#/R-HSA-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) TAS Homo sapiens 2410 R-HSA-8982637 https://reactome.org/PathwayBrowser/#/R-HSA-8982637 Opsins binds G alpha-t TAS Homo sapiens 2410 R-HSA-9021596 https://reactome.org/PathwayBrowser/#/R-HSA-9021596 Membrane estrogen receptors bind SRC TAS Homo sapiens 2410 R-HSA-9021600 https://reactome.org/PathwayBrowser/#/R-HSA-9021600 G-proteins dissociate from plasma-membrane estrogen receptors TAS Homo sapiens 2410 R-HSA-9021601 https://reactome.org/PathwayBrowser/#/R-HSA-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG TAS Homo sapiens 2410 R-HSA-9935449 https://reactome.org/PathwayBrowser/#/R-HSA-9935449 FUT10 O-fucosylates EMI domain-containing proteins TAS Homo sapiens 2410 R-HSA-9935469 https://reactome.org/PathwayBrowser/#/R-HSA-9935469 FUT11 O-fucosylates EMI domain-containing proteins TAS Homo sapiens 2410 R-MMU-114552 https://reactome.org/PathwayBrowser/#/R-MMU-114552 Thrombin-activated PARs activate G12/13 IEA Mus musculus 2410 R-MMU-114558 https://reactome.org/PathwayBrowser/#/R-MMU-114558 Thrombin-activated PARs activate Gq IEA Mus musculus 2410 R-MMU-1458501 https://reactome.org/PathwayBrowser/#/R-MMU-1458501 RalA Hydrolyzes GTP TAS Mus musculus 2410 R-MMU-170674 https://reactome.org/PathwayBrowser/#/R-MMU-170674 Dissociation of the Gi alpha:G olf complex IEA Mus musculus 2410 R-MMU-170686 https://reactome.org/PathwayBrowser/#/R-MMU-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Mus musculus 2410 R-MMU-205039 https://reactome.org/PathwayBrowser/#/R-MMU-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Mus musculus 2410 R-MMU-2255339 https://reactome.org/PathwayBrowser/#/R-MMU-2255339 RalA Exchanges GDP for GTP TAS Mus musculus 2410 R-MMU-2255341 https://reactome.org/PathwayBrowser/#/R-MMU-2255341 Rab8A/10/13/14 Exchange GDP for GTP TAS Mus musculus 2410 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 2410 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2410 R-MMU-381727 https://reactome.org/PathwayBrowser/#/R-MMU-381727 RAP1A exchanges GDP for GTP IEA Mus musculus 2410 R-MMU-392187 https://reactome.org/PathwayBrowser/#/R-MMU-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Mus musculus 2410 R-MMU-392195 https://reactome.org/PathwayBrowser/#/R-MMU-392195 Gi activation by P2Y purinoceptor 12 IEA Mus musculus 2410 R-MMU-3928612 https://reactome.org/PathwayBrowser/#/R-MMU-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Mus musculus 2410 R-MMU-3928633 https://reactome.org/PathwayBrowser/#/R-MMU-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Mus musculus 2410 R-MMU-392870 https://reactome.org/PathwayBrowser/#/R-MMU-392870 Gs activation by prostacyclin receptor IEA Mus musculus 2410 R-MMU-396996 https://reactome.org/PathwayBrowser/#/R-MMU-396996 Thrombin-activated PARs binds G-protein Gq IEA Mus musculus 2410 R-MMU-416530 https://reactome.org/PathwayBrowser/#/R-MMU-416530 FFAR1:FFAR1 ligands activate Gq IEA Mus musculus 2410 R-MMU-416546 https://reactome.org/PathwayBrowser/#/R-MMU-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Mus musculus 2410 R-MMU-416588 https://reactome.org/PathwayBrowser/#/R-MMU-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Mus musculus 2410 R-MMU-418574 https://reactome.org/PathwayBrowser/#/R-MMU-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Mus musculus 2410 R-MMU-418582 https://reactome.org/PathwayBrowser/#/R-MMU-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Mus musculus 2410 R-MMU-419166 https://reactome.org/PathwayBrowser/#/R-MMU-419166 GEFs activate RhoA,B,C IEA Mus musculus 2410 R-MMU-420883 https://reactome.org/PathwayBrowser/#/R-MMU-420883 Opsins act as GEFs for G alpha-t IEA Mus musculus 2410 R-MMU-426547 https://reactome.org/PathwayBrowser/#/R-MMU-426547 Activation of Gq by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 2410 R-MMU-427858 https://reactome.org/PathwayBrowser/#/R-MMU-427858 Thrombin-activated PAR binds G-protein G12/13 TAS Mus musculus 2410 R-MMU-428749 https://reactome.org/PathwayBrowser/#/R-MMU-428749 Activated TP receptor binds G-proten Gq IEA Mus musculus 2410 R-MMU-428750 https://reactome.org/PathwayBrowser/#/R-MMU-428750 Gq activation by TP receptor IEA Mus musculus 2410 R-MMU-428909 https://reactome.org/PathwayBrowser/#/R-MMU-428909 Activated TP receptor binds G-protein G13 IEA Mus musculus 2410 R-MMU-428917 https://reactome.org/PathwayBrowser/#/R-MMU-428917 G13 activation by TP receptor IEA Mus musculus 2410 R-MMU-481009 https://reactome.org/PathwayBrowser/#/R-MMU-481009 Exocytosis of platelet dense granule content IEA Mus musculus 2410 R-MMU-5638006 https://reactome.org/PathwayBrowser/#/R-MMU-5638006 ARL3 hydrolyzes GTP IEA Mus musculus 2410 R-MMU-5638016 https://reactome.org/PathwayBrowser/#/R-MMU-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Mus musculus 2410 R-MMU-749446 https://reactome.org/PathwayBrowser/#/R-MMU-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Mus musculus 2410 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 2410 R-MMU-749453 https://reactome.org/PathwayBrowser/#/R-MMU-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Mus musculus 2410 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2410 R-MMU-750988 https://reactome.org/PathwayBrowser/#/R-MMU-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Mus musculus 2410 R-MMU-750993 https://reactome.org/PathwayBrowser/#/R-MMU-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Mus musculus 2410 R-MMU-751001 https://reactome.org/PathwayBrowser/#/R-MMU-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Mus musculus 2410 R-MMU-751027 https://reactome.org/PathwayBrowser/#/R-MMU-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Mus musculus 2410 R-MMU-751029 https://reactome.org/PathwayBrowser/#/R-MMU-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Mus musculus 2410 R-MMU-751039 https://reactome.org/PathwayBrowser/#/R-MMU-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Mus musculus 2410 R-MMU-77081 https://reactome.org/PathwayBrowser/#/R-MMU-77081 Formation of the CE:GMP intermediate complex IEA Mus musculus 2410 R-MMU-8854329 https://reactome.org/PathwayBrowser/#/R-MMU-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Mus musculus 2410 R-MMU-8854604 https://reactome.org/PathwayBrowser/#/R-MMU-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Mus musculus 2410 R-MMU-8982012 https://reactome.org/PathwayBrowser/#/R-MMU-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Mus musculus 2410 R-MMU-8982018 https://reactome.org/PathwayBrowser/#/R-MMU-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Mus musculus 2410 R-MMU-8982026 https://reactome.org/PathwayBrowser/#/R-MMU-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Mus musculus 2410 R-MMU-8982637 https://reactome.org/PathwayBrowser/#/R-MMU-8982637 Opsins binds G alpha-t IEA Mus musculus 2410 R-MMU-9021596 https://reactome.org/PathwayBrowser/#/R-MMU-9021596 Membrane estrogen receptors bind SRC IEA Mus musculus 2410 R-MMU-9021600 https://reactome.org/PathwayBrowser/#/R-MMU-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Mus musculus 2410 R-MMU-9021601 https://reactome.org/PathwayBrowser/#/R-MMU-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Mus musculus 2410 R-MMU-9935449 https://reactome.org/PathwayBrowser/#/R-MMU-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Mus musculus 2410 R-MMU-9935469 https://reactome.org/PathwayBrowser/#/R-MMU-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Mus musculus 2410 R-NUL-1986584 https://reactome.org/PathwayBrowser/#/R-NUL-1986584 Fucosylation of Pre-Notch by POFUT1 TAS Cricetulus griseus 2410 R-NUL-428715 https://reactome.org/PathwayBrowser/#/R-NUL-428715 Activated human P2Y purinoceptor 1 binds mouse G-protein Gq TAS Homo sapiens 2410 R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 2410 R-NUL-8982712 https://reactome.org/PathwayBrowser/#/R-NUL-8982712 Gz(rat):PKC(cow) dissociates to give phosphorylated G alpha (z) TAS Bos taurus 2410 R-PFA-481009 https://reactome.org/PathwayBrowser/#/R-PFA-481009 Exocytosis of platelet dense granule content IEA Plasmodium falciparum 2410 R-PFA-77081 https://reactome.org/PathwayBrowser/#/R-PFA-77081 Formation of the CE:GMP intermediate complex IEA Plasmodium falciparum 2410 R-PFA-8854329 https://reactome.org/PathwayBrowser/#/R-PFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 2410 R-RNO-114558 https://reactome.org/PathwayBrowser/#/R-RNO-114558 Thrombin-activated PARs activate Gq IEA Rattus norvegicus 2410 R-RNO-170674 https://reactome.org/PathwayBrowser/#/R-RNO-170674 Dissociation of the Gi alpha:G olf complex IEA Rattus norvegicus 2410 R-RNO-170686 https://reactome.org/PathwayBrowser/#/R-RNO-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Rattus norvegicus 2410 R-RNO-205039 https://reactome.org/PathwayBrowser/#/R-RNO-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Rattus norvegicus 2410 R-RNO-2457808 https://reactome.org/PathwayBrowser/#/R-RNO-2457808 Rab8A/13/14 Exchange GDP for GTP TAS Rattus norvegicus 2410 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 2410 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2410 R-RNO-381727 https://reactome.org/PathwayBrowser/#/R-RNO-381727 RAP1A exchanges GDP for GTP IEA Rattus norvegicus 2410 R-RNO-392195 https://reactome.org/PathwayBrowser/#/R-RNO-392195 Gi activation by P2Y purinoceptor 12 IEA Rattus norvegicus 2410 R-RNO-3928612 https://reactome.org/PathwayBrowser/#/R-RNO-3928612 KALRN exchanges GTP for GDP on RAC1, activating it IEA Rattus norvegicus 2410 R-RNO-3928633 https://reactome.org/PathwayBrowser/#/R-RNO-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Rattus norvegicus 2410 R-RNO-416530 https://reactome.org/PathwayBrowser/#/R-RNO-416530 FFAR1:FFAR1 ligands activate Gq IEA Rattus norvegicus 2410 R-RNO-416546 https://reactome.org/PathwayBrowser/#/R-RNO-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Rattus norvegicus 2410 R-RNO-416588 https://reactome.org/PathwayBrowser/#/R-RNO-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Rattus norvegicus 2410 R-RNO-418574 https://reactome.org/PathwayBrowser/#/R-RNO-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Rattus norvegicus 2410 R-RNO-418582 https://reactome.org/PathwayBrowser/#/R-RNO-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Rattus norvegicus 2410 R-RNO-419166 https://reactome.org/PathwayBrowser/#/R-RNO-419166 GEFs activate RhoA,B,C IEA Rattus norvegicus 2410 R-RNO-420883 https://reactome.org/PathwayBrowser/#/R-RNO-420883 Opsins act as GEFs for G alpha-t IEA Rattus norvegicus 2410 R-RNO-421896 https://reactome.org/PathwayBrowser/#/R-RNO-421896 G alpha (i)1 auto-inactivates by hydrolysing GTP to GDP TAS Rattus norvegicus 2410 R-RNO-428750 https://reactome.org/PathwayBrowser/#/R-RNO-428750 Gq activation by TP receptor IEA Rattus norvegicus 2410 R-RNO-428917 https://reactome.org/PathwayBrowser/#/R-RNO-428917 G13 activation by TP receptor IEA Rattus norvegicus 2410 R-RNO-446954 https://reactome.org/PathwayBrowser/#/R-RNO-446954 Activation of G(s) by the Glucagon-like peptide-1 receptor (Glp1r, rat) TAS Rattus norvegicus 2410 R-RNO-481009 https://reactome.org/PathwayBrowser/#/R-RNO-481009 Exocytosis of platelet dense granule content IEA Rattus norvegicus 2410 R-RNO-5638006 https://reactome.org/PathwayBrowser/#/R-RNO-5638006 ARL3 hydrolyzes GTP IEA Rattus norvegicus 2410 R-RNO-5638016 https://reactome.org/PathwayBrowser/#/R-RNO-5638016 RP2:ARL3:GDP:UNC119B dissociates IEA Rattus norvegicus 2410 R-RNO-749453 https://reactome.org/PathwayBrowser/#/R-RNO-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Rattus norvegicus 2410 R-RNO-77081 https://reactome.org/PathwayBrowser/#/R-RNO-77081 Formation of the CE:GMP intermediate complex IEA Rattus norvegicus 2410 R-RNO-8854329 https://reactome.org/PathwayBrowser/#/R-RNO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 2410 R-RNO-8854604 https://reactome.org/PathwayBrowser/#/R-RNO-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Rattus norvegicus 2410 R-RNO-8982012 https://reactome.org/PathwayBrowser/#/R-RNO-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Rattus norvegicus 2410 R-RNO-8982018 https://reactome.org/PathwayBrowser/#/R-RNO-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Rattus norvegicus 2410 R-RNO-8982026 https://reactome.org/PathwayBrowser/#/R-RNO-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Rattus norvegicus 2410 R-RNO-9021596 https://reactome.org/PathwayBrowser/#/R-RNO-9021596 Membrane estrogen receptors bind SRC IEA Rattus norvegicus 2410 R-RNO-9935449 https://reactome.org/PathwayBrowser/#/R-RNO-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Rattus norvegicus 2410 R-RNO-9935469 https://reactome.org/PathwayBrowser/#/R-RNO-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Rattus norvegicus 2410 R-SCE-381727 https://reactome.org/PathwayBrowser/#/R-SCE-381727 RAP1A exchanges GDP for GTP IEA Saccharomyces cerevisiae 2410 R-SCE-418574 https://reactome.org/PathwayBrowser/#/R-SCE-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Saccharomyces cerevisiae 2410 R-SCE-418582 https://reactome.org/PathwayBrowser/#/R-SCE-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Saccharomyces cerevisiae 2410 R-SCE-419166 https://reactome.org/PathwayBrowser/#/R-SCE-419166 GEFs activate RhoA,B,C IEA Saccharomyces cerevisiae 2410 R-SCE-481009 https://reactome.org/PathwayBrowser/#/R-SCE-481009 Exocytosis of platelet dense granule content IEA Saccharomyces cerevisiae 2410 R-SCE-77081 https://reactome.org/PathwayBrowser/#/R-SCE-77081 Formation of the CE:GMP intermediate complex IEA Saccharomyces cerevisiae 2410 R-SCE-8854329 https://reactome.org/PathwayBrowser/#/R-SCE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 2410 R-SCE-8982012 https://reactome.org/PathwayBrowser/#/R-SCE-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Saccharomyces cerevisiae 2410 R-SCE-8982018 https://reactome.org/PathwayBrowser/#/R-SCE-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Saccharomyces cerevisiae 2410 R-SCE-8982026 https://reactome.org/PathwayBrowser/#/R-SCE-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Saccharomyces cerevisiae 2410 R-SPO-418574 https://reactome.org/PathwayBrowser/#/R-SPO-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Schizosaccharomyces pombe 2410 R-SPO-418582 https://reactome.org/PathwayBrowser/#/R-SPO-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Schizosaccharomyces pombe 2410 R-SPO-419166 https://reactome.org/PathwayBrowser/#/R-SPO-419166 GEFs activate RhoA,B,C IEA Schizosaccharomyces pombe 2410 R-SPO-481009 https://reactome.org/PathwayBrowser/#/R-SPO-481009 Exocytosis of platelet dense granule content IEA Schizosaccharomyces pombe 2410 R-SPO-77081 https://reactome.org/PathwayBrowser/#/R-SPO-77081 Formation of the CE:GMP intermediate complex IEA Schizosaccharomyces pombe 2410 R-SPO-8854329 https://reactome.org/PathwayBrowser/#/R-SPO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 2410 R-SPO-8982012 https://reactome.org/PathwayBrowser/#/R-SPO-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Schizosaccharomyces pombe 2410 R-SPO-8982018 https://reactome.org/PathwayBrowser/#/R-SPO-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Schizosaccharomyces pombe 2410 R-SPO-8982026 https://reactome.org/PathwayBrowser/#/R-SPO-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Schizosaccharomyces pombe 2410 R-SSC-114552 https://reactome.org/PathwayBrowser/#/R-SSC-114552 Thrombin-activated PARs activate G12/13 IEA Sus scrofa 2410 R-SSC-114558 https://reactome.org/PathwayBrowser/#/R-SSC-114558 Thrombin-activated PARs activate Gq IEA Sus scrofa 2410 R-SSC-170674 https://reactome.org/PathwayBrowser/#/R-SSC-170674 Dissociation of the Gi alpha:G olf complex IEA Sus scrofa 2410 R-SSC-170686 https://reactome.org/PathwayBrowser/#/R-SSC-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Sus scrofa 2410 R-SSC-205039 https://reactome.org/PathwayBrowser/#/R-SSC-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Sus scrofa 2410 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 2410 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2410 R-SSC-381727 https://reactome.org/PathwayBrowser/#/R-SSC-381727 RAP1A exchanges GDP for GTP IEA Sus scrofa 2410 R-SSC-392187 https://reactome.org/PathwayBrowser/#/R-SSC-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Sus scrofa 2410 R-SSC-392195 https://reactome.org/PathwayBrowser/#/R-SSC-392195 Gi activation by P2Y purinoceptor 12 IEA Sus scrofa 2410 R-SSC-3928633 https://reactome.org/PathwayBrowser/#/R-SSC-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Sus scrofa 2410 R-SSC-392870 https://reactome.org/PathwayBrowser/#/R-SSC-392870 Gs activation by prostacyclin receptor IEA Sus scrofa 2410 R-SSC-396996 https://reactome.org/PathwayBrowser/#/R-SSC-396996 Thrombin-activated PARs binds G-protein Gq IEA Sus scrofa 2410 R-SSC-416546 https://reactome.org/PathwayBrowser/#/R-SSC-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Sus scrofa 2410 R-SSC-416588 https://reactome.org/PathwayBrowser/#/R-SSC-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Sus scrofa 2410 R-SSC-418574 https://reactome.org/PathwayBrowser/#/R-SSC-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa 2410 R-SSC-418582 https://reactome.org/PathwayBrowser/#/R-SSC-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Sus scrofa 2410 R-SSC-419166 https://reactome.org/PathwayBrowser/#/R-SSC-419166 GEFs activate RhoA,B,C IEA Sus scrofa 2410 R-SSC-420883 https://reactome.org/PathwayBrowser/#/R-SSC-420883 Opsins act as GEFs for G alpha-t IEA Sus scrofa 2410 R-SSC-428749 https://reactome.org/PathwayBrowser/#/R-SSC-428749 Activated TP receptor binds G-proten Gq IEA Sus scrofa 2410 R-SSC-428750 https://reactome.org/PathwayBrowser/#/R-SSC-428750 Gq activation by TP receptor IEA Sus scrofa 2410 R-SSC-428909 https://reactome.org/PathwayBrowser/#/R-SSC-428909 Activated TP receptor binds G-protein G13 IEA Sus scrofa 2410 R-SSC-428917 https://reactome.org/PathwayBrowser/#/R-SSC-428917 G13 activation by TP receptor IEA Sus scrofa 2410 R-SSC-481009 https://reactome.org/PathwayBrowser/#/R-SSC-481009 Exocytosis of platelet dense granule content IEA Sus scrofa 2410 R-SSC-749446 https://reactome.org/PathwayBrowser/#/R-SSC-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Sus scrofa 2410 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 2410 R-SSC-749453 https://reactome.org/PathwayBrowser/#/R-SSC-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Sus scrofa 2410 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2410 R-SSC-750988 https://reactome.org/PathwayBrowser/#/R-SSC-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Sus scrofa 2410 R-SSC-750993 https://reactome.org/PathwayBrowser/#/R-SSC-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Sus scrofa 2410 R-SSC-751001 https://reactome.org/PathwayBrowser/#/R-SSC-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Sus scrofa 2410 R-SSC-751027 https://reactome.org/PathwayBrowser/#/R-SSC-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Sus scrofa 2410 R-SSC-751029 https://reactome.org/PathwayBrowser/#/R-SSC-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Sus scrofa 2410 R-SSC-751039 https://reactome.org/PathwayBrowser/#/R-SSC-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Sus scrofa 2410 R-SSC-77081 https://reactome.org/PathwayBrowser/#/R-SSC-77081 Formation of the CE:GMP intermediate complex IEA Sus scrofa 2410 R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 2410 R-SSC-8854604 https://reactome.org/PathwayBrowser/#/R-SSC-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Sus scrofa 2410 R-SSC-8982012 https://reactome.org/PathwayBrowser/#/R-SSC-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Sus scrofa 2410 R-SSC-8982018 https://reactome.org/PathwayBrowser/#/R-SSC-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Sus scrofa 2410 R-SSC-8982026 https://reactome.org/PathwayBrowser/#/R-SSC-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Sus scrofa 2410 R-SSC-8982637 https://reactome.org/PathwayBrowser/#/R-SSC-8982637 Opsins binds G alpha-t IEA Sus scrofa 2410 R-SSC-9021596 https://reactome.org/PathwayBrowser/#/R-SSC-9021596 Membrane estrogen receptors bind SRC IEA Sus scrofa 2410 R-SSC-9021600 https://reactome.org/PathwayBrowser/#/R-SSC-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Sus scrofa 2410 R-SSC-9021601 https://reactome.org/PathwayBrowser/#/R-SSC-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Sus scrofa 2410 R-SSC-9935449 https://reactome.org/PathwayBrowser/#/R-SSC-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Sus scrofa 2410 R-SSC-9935469 https://reactome.org/PathwayBrowser/#/R-SSC-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Sus scrofa 2410 R-XTR-114552 https://reactome.org/PathwayBrowser/#/R-XTR-114552 Thrombin-activated PARs activate G12/13 IEA Xenopus tropicalis 2410 R-XTR-114558 https://reactome.org/PathwayBrowser/#/R-XTR-114558 Thrombin-activated PARs activate Gq IEA Xenopus tropicalis 2410 R-XTR-170674 https://reactome.org/PathwayBrowser/#/R-XTR-170674 Dissociation of the Gi alpha:G olf complex IEA Xenopus tropicalis 2410 R-XTR-170686 https://reactome.org/PathwayBrowser/#/R-XTR-170686 Adenylate cyclase increases the GTPase activity of Gi alpha IEA Xenopus tropicalis 2410 R-XTR-205039 https://reactome.org/PathwayBrowser/#/R-XTR-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor IEA Xenopus tropicalis 2410 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2410 R-XTR-381727 https://reactome.org/PathwayBrowser/#/R-XTR-381727 RAP1A exchanges GDP for GTP IEA Xenopus tropicalis 2410 R-XTR-392187 https://reactome.org/PathwayBrowser/#/R-XTR-392187 Activated P2Y purinoceptor 12 binds G-protein Gi IEA Xenopus tropicalis 2410 R-XTR-392195 https://reactome.org/PathwayBrowser/#/R-XTR-392195 Gi activation by P2Y purinoceptor 12 IEA Xenopus tropicalis 2410 R-XTR-3928633 https://reactome.org/PathwayBrowser/#/R-XTR-3928633 bPIX exchanges GTP for GDP on RAC, activating it IEA Xenopus tropicalis 2410 R-XTR-392870 https://reactome.org/PathwayBrowser/#/R-XTR-392870 Gs activation by prostacyclin receptor IEA Xenopus tropicalis 2410 R-XTR-396996 https://reactome.org/PathwayBrowser/#/R-XTR-396996 Thrombin-activated PARs binds G-protein Gq IEA Xenopus tropicalis 2410 R-XTR-416546 https://reactome.org/PathwayBrowser/#/R-XTR-416546 Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity IEA Xenopus tropicalis 2410 R-XTR-416588 https://reactome.org/PathwayBrowser/#/R-XTR-416588 Activation of Rho by LARG and PDZ-RhoGEF IEA Xenopus tropicalis 2410 R-XTR-418574 https://reactome.org/PathwayBrowser/#/R-XTR-418574 G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP IEA Xenopus tropicalis 2410 R-XTR-418582 https://reactome.org/PathwayBrowser/#/R-XTR-418582 G alpha (q) auto-inactivates by hydrolysing GTP to GDP IEA Xenopus tropicalis 2410 R-XTR-419166 https://reactome.org/PathwayBrowser/#/R-XTR-419166 GEFs activate RhoA,B,C IEA Xenopus tropicalis 2410 R-XTR-420883 https://reactome.org/PathwayBrowser/#/R-XTR-420883 Opsins act as GEFs for G alpha-t IEA Xenopus tropicalis 2410 R-XTR-428749 https://reactome.org/PathwayBrowser/#/R-XTR-428749 Activated TP receptor binds G-proten Gq IEA Xenopus tropicalis 2410 R-XTR-428750 https://reactome.org/PathwayBrowser/#/R-XTR-428750 Gq activation by TP receptor IEA Xenopus tropicalis 2410 R-XTR-428909 https://reactome.org/PathwayBrowser/#/R-XTR-428909 Activated TP receptor binds G-protein G13 IEA Xenopus tropicalis 2410 R-XTR-428917 https://reactome.org/PathwayBrowser/#/R-XTR-428917 G13 activation by TP receptor IEA Xenopus tropicalis 2410 R-XTR-481009 https://reactome.org/PathwayBrowser/#/R-XTR-481009 Exocytosis of platelet dense granule content IEA Xenopus tropicalis 2410 R-XTR-749446 https://reactome.org/PathwayBrowser/#/R-XTR-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz IEA Xenopus tropicalis 2410 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 2410 R-XTR-749453 https://reactome.org/PathwayBrowser/#/R-XTR-749453 Liganded Gz-activating GPCR acts as a GEF for Gz IEA Xenopus tropicalis 2410 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2410 R-XTR-750988 https://reactome.org/PathwayBrowser/#/R-XTR-750988 Inactive G alpha (z) reassociates with G beta:gamma IEA Xenopus tropicalis 2410 R-XTR-750993 https://reactome.org/PathwayBrowser/#/R-XTR-750993 Inactive G alpha (q) reassociates with G beta:gamma IEA Xenopus tropicalis 2410 R-XTR-751001 https://reactome.org/PathwayBrowser/#/R-XTR-751001 Inactive G alpha (i) reassociates with G beta:gamma IEA Xenopus tropicalis 2410 R-XTR-751027 https://reactome.org/PathwayBrowser/#/R-XTR-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 IEA Xenopus tropicalis 2410 R-XTR-751029 https://reactome.org/PathwayBrowser/#/R-XTR-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 IEA Xenopus tropicalis 2410 R-XTR-751039 https://reactome.org/PathwayBrowser/#/R-XTR-751039 Inactive G alpha (12/13) reassociates with G beta:gamma IEA Xenopus tropicalis 2410 R-XTR-77081 https://reactome.org/PathwayBrowser/#/R-XTR-77081 Formation of the CE:GMP intermediate complex IEA Xenopus tropicalis 2410 R-XTR-8854329 https://reactome.org/PathwayBrowser/#/R-XTR-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 2410 R-XTR-8982012 https://reactome.org/PathwayBrowser/#/R-XTR-8982012 G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 IEA Xenopus tropicalis 2410 R-XTR-8982018 https://reactome.org/PathwayBrowser/#/R-XTR-8982018 G alpha (z):RGS complex dissociates to give inactive G alpha (z) IEA Xenopus tropicalis 2410 R-XTR-8982026 https://reactome.org/PathwayBrowser/#/R-XTR-8982026 G alpha (q):RGS dissociates to inactive G alpha (q) IEA Xenopus tropicalis 2410 R-XTR-8982637 https://reactome.org/PathwayBrowser/#/R-XTR-8982637 Opsins binds G alpha-t IEA Xenopus tropicalis 2410 R-XTR-9021600 https://reactome.org/PathwayBrowser/#/R-XTR-9021600 G-proteins dissociate from plasma-membrane estrogen receptors IEA Xenopus tropicalis 2410 R-XTR-9021601 https://reactome.org/PathwayBrowser/#/R-XTR-9021601 Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG IEA Xenopus tropicalis 2410 R-XTR-9935449 https://reactome.org/PathwayBrowser/#/R-XTR-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Xenopus tropicalis 2410 R-XTR-9935469 https://reactome.org/PathwayBrowser/#/R-XTR-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Xenopus tropicalis 2411 R-BTA-9691566 https://reactome.org/PathwayBrowser/#/R-BTA-9691566 KCNJ11:ABCC9 binds nicorandil IEA Bos taurus 2411 R-CFA-9691566 https://reactome.org/PathwayBrowser/#/R-CFA-9691566 KCNJ11:ABCC9 binds nicorandil IEA Canis familiaris 2411 R-DME-9691566 https://reactome.org/PathwayBrowser/#/R-DME-9691566 KCNJ11:ABCC9 binds nicorandil IEA Drosophila melanogaster 2411 R-GGA-9691566 https://reactome.org/PathwayBrowser/#/R-GGA-9691566 KCNJ11:ABCC9 binds nicorandil IEA Gallus gallus 2411 R-HSA-9691566 https://reactome.org/PathwayBrowser/#/R-HSA-9691566 KCNJ11:ABCC9 binds nicorandil TAS Homo sapiens 2411 R-MMU-9691566 https://reactome.org/PathwayBrowser/#/R-MMU-9691566 KCNJ11:ABCC9 binds nicorandil IEA Mus musculus 2411 R-RNO-9691566 https://reactome.org/PathwayBrowser/#/R-RNO-9691566 KCNJ11:ABCC9 binds nicorandil IEA Rattus norvegicus 2411 R-SSC-9691566 https://reactome.org/PathwayBrowser/#/R-SSC-9691566 KCNJ11:ABCC9 binds nicorandil IEA Sus scrofa 2411 R-XTR-9691566 https://reactome.org/PathwayBrowser/#/R-XTR-9691566 KCNJ11:ABCC9 binds nicorandil IEA Xenopus tropicalis 2414 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 2414 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 2414 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 2414 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 2414 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 2414 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 2414 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 2414 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 2414 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 2420 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 2420 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2420 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2420 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2420 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2420 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 2420 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2420 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2420 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2420 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2420 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 2420 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2420 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2420 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 2420 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2420 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2420 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2420 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2420 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 2420 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2420 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2420 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2420 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2420 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2420 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2420 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 2420 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2420 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2420 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2420 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2420 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 2420 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2420 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2420 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 2420 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2420 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2420 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2420 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2420 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 2420 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2420 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2420 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2421 R-BTA-2671885 https://reactome.org/PathwayBrowser/#/R-BTA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Bos taurus 2421 R-BTA-2672334 https://reactome.org/PathwayBrowser/#/R-BTA-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Bos taurus 2421 R-BTA-9649963 https://reactome.org/PathwayBrowser/#/R-BTA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Bos taurus 2421 R-CEL-2671885 https://reactome.org/PathwayBrowser/#/R-CEL-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Caenorhabditis elegans 2421 R-CEL-2672334 https://reactome.org/PathwayBrowser/#/R-CEL-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Caenorhabditis elegans 2421 R-CEL-9649963 https://reactome.org/PathwayBrowser/#/R-CEL-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Caenorhabditis elegans 2421 R-CFA-2671885 https://reactome.org/PathwayBrowser/#/R-CFA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Canis familiaris 2421 R-CFA-2672334 https://reactome.org/PathwayBrowser/#/R-CFA-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Canis familiaris 2421 R-CFA-9649963 https://reactome.org/PathwayBrowser/#/R-CFA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Canis familiaris 2421 R-DME-2671885 https://reactome.org/PathwayBrowser/#/R-DME-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Drosophila melanogaster 2421 R-DME-9649963 https://reactome.org/PathwayBrowser/#/R-DME-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Drosophila melanogaster 2421 R-DRE-2671885 https://reactome.org/PathwayBrowser/#/R-DRE-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Danio rerio 2421 R-DRE-9649963 https://reactome.org/PathwayBrowser/#/R-DRE-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Danio rerio 2421 R-GGA-2671885 https://reactome.org/PathwayBrowser/#/R-GGA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Gallus gallus 2421 R-GGA-2672334 https://reactome.org/PathwayBrowser/#/R-GGA-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Gallus gallus 2421 R-GGA-9649963 https://reactome.org/PathwayBrowser/#/R-GGA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Gallus gallus 2421 R-HSA-2671885 https://reactome.org/PathwayBrowser/#/R-HSA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol TAS Homo sapiens 2421 R-HSA-2672334 https://reactome.org/PathwayBrowser/#/R-HSA-2672334 SCNN channels transport extracellular Na+ to cytosol TAS Homo sapiens 2421 R-HSA-9649963 https://reactome.org/PathwayBrowser/#/R-HSA-9649963 ASIC3 channel blockers bind ASIC3 trimer TAS Homo sapiens 2421 R-MMU-2671885 https://reactome.org/PathwayBrowser/#/R-MMU-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Mus musculus 2421 R-MMU-2672334 https://reactome.org/PathwayBrowser/#/R-MMU-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Mus musculus 2421 R-MMU-9649963 https://reactome.org/PathwayBrowser/#/R-MMU-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Mus musculus 2421 R-RNO-2671885 https://reactome.org/PathwayBrowser/#/R-RNO-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Rattus norvegicus 2421 R-RNO-2672334 https://reactome.org/PathwayBrowser/#/R-RNO-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Rattus norvegicus 2421 R-RNO-9649963 https://reactome.org/PathwayBrowser/#/R-RNO-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Rattus norvegicus 2421 R-SSC-2671885 https://reactome.org/PathwayBrowser/#/R-SSC-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Sus scrofa 2421 R-SSC-2672334 https://reactome.org/PathwayBrowser/#/R-SSC-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Sus scrofa 2421 R-SSC-9649963 https://reactome.org/PathwayBrowser/#/R-SSC-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Sus scrofa 2421 R-XTR-2671885 https://reactome.org/PathwayBrowser/#/R-XTR-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Xenopus tropicalis 2421 R-XTR-2672334 https://reactome.org/PathwayBrowser/#/R-XTR-2672334 SCNN channels transport extracellular Na+ to cytosol IEA Xenopus tropicalis 2421 R-XTR-9649963 https://reactome.org/PathwayBrowser/#/R-XTR-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Xenopus tropicalis 2422 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 2422 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2422 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2422 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2422 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2422 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 2422 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2422 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2422 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2422 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2422 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 2422 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2422 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2422 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 2422 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2422 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2422 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2422 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2422 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 2422 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2422 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2422 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2422 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2422 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2422 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2422 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 2422 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2422 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2422 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2422 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2422 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 2422 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2422 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2422 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 2422 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2422 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2422 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2422 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2422 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 2422 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2422 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2422 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2424 R-BTA-9696323 https://reactome.org/PathwayBrowser/#/R-BTA-9696323 CNRs bind CNR agonists IEA Bos taurus 2424 R-CFA-9696323 https://reactome.org/PathwayBrowser/#/R-CFA-9696323 CNRs bind CNR agonists IEA Canis familiaris 2424 R-DRE-9696323 https://reactome.org/PathwayBrowser/#/R-DRE-9696323 CNRs bind CNR agonists IEA Danio rerio 2424 R-GGA-9696323 https://reactome.org/PathwayBrowser/#/R-GGA-9696323 CNRs bind CNR agonists IEA Gallus gallus 2424 R-HSA-9696323 https://reactome.org/PathwayBrowser/#/R-HSA-9696323 CNRs bind CNR agonists TAS Homo sapiens 2424 R-MMU-9696323 https://reactome.org/PathwayBrowser/#/R-MMU-9696323 CNRs bind CNR agonists IEA Mus musculus 2424 R-RNO-9696323 https://reactome.org/PathwayBrowser/#/R-RNO-9696323 CNRs bind CNR agonists IEA Rattus norvegicus 2424 R-SSC-9696323 https://reactome.org/PathwayBrowser/#/R-SSC-9696323 CNRs bind CNR agonists IEA Sus scrofa 2424 R-XTR-9696323 https://reactome.org/PathwayBrowser/#/R-XTR-9696323 CNRs bind CNR agonists IEA Xenopus tropicalis 2425 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 2425 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 2425 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 2425 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 2425 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 2425 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 2425 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 2425 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 2425 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 2427 R-HSA-9911462 https://reactome.org/PathwayBrowser/#/R-HSA-9911462 Aminoglycoside antibiotics bind Kpn 16S rRNA TAS Homo sapiens 2427 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 2427 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 2430 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 2430 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 2430 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 2430 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 2430 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 2430 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 2430 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 2430 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 2430 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 2432 R-BTA-9701147 https://reactome.org/PathwayBrowser/#/R-BTA-9701147 TRPV1 binds TRPV1 blockers IEA Bos taurus 2432 R-CEL-9701147 https://reactome.org/PathwayBrowser/#/R-CEL-9701147 TRPV1 binds TRPV1 blockers IEA Caenorhabditis elegans 2432 R-CFA-9701147 https://reactome.org/PathwayBrowser/#/R-CFA-9701147 TRPV1 binds TRPV1 blockers IEA Canis familiaris 2432 R-DME-9701147 https://reactome.org/PathwayBrowser/#/R-DME-9701147 TRPV1 binds TRPV1 blockers IEA Drosophila melanogaster 2432 R-DRE-9701147 https://reactome.org/PathwayBrowser/#/R-DRE-9701147 TRPV1 binds TRPV1 blockers IEA Danio rerio 2432 R-GGA-9701147 https://reactome.org/PathwayBrowser/#/R-GGA-9701147 TRPV1 binds TRPV1 blockers IEA Gallus gallus 2432 R-HSA-9701147 https://reactome.org/PathwayBrowser/#/R-HSA-9701147 TRPV1 binds TRPV1 blockers TAS Homo sapiens 2432 R-MMU-9701147 https://reactome.org/PathwayBrowser/#/R-MMU-9701147 TRPV1 binds TRPV1 blockers IEA Mus musculus 2432 R-RNO-9701147 https://reactome.org/PathwayBrowser/#/R-RNO-9701147 TRPV1 binds TRPV1 blockers IEA Rattus norvegicus 2432 R-SCE-9701147 https://reactome.org/PathwayBrowser/#/R-SCE-9701147 TRPV1 binds TRPV1 blockers IEA Saccharomyces cerevisiae 2432 R-SSC-9701147 https://reactome.org/PathwayBrowser/#/R-SSC-9701147 TRPV1 binds TRPV1 blockers IEA Sus scrofa 2432 R-XTR-9701147 https://reactome.org/PathwayBrowser/#/R-XTR-9701147 TRPV1 binds TRPV1 blockers IEA Xenopus tropicalis 2447 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2447 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2447 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2447 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2447 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2447 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2447 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2447 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2447 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2447 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2450 R-BTA-2685505 https://reactome.org/PathwayBrowser/#/R-BTA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Bos taurus 2450 R-CFA-2685505 https://reactome.org/PathwayBrowser/#/R-CFA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Canis familiaris 2450 R-DRE-2685505 https://reactome.org/PathwayBrowser/#/R-DRE-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Danio rerio 2450 R-GGA-2685505 https://reactome.org/PathwayBrowser/#/R-GGA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Gallus gallus 2450 R-HSA-2685505 https://reactome.org/PathwayBrowser/#/R-HSA-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol TAS Homo sapiens 2450 R-MMU-2685505 https://reactome.org/PathwayBrowser/#/R-MMU-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Mus musculus 2450 R-RNO-2685505 https://reactome.org/PathwayBrowser/#/R-RNO-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Rattus norvegicus 2450 R-SSC-2685505 https://reactome.org/PathwayBrowser/#/R-SSC-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Sus scrofa 2450 R-XTR-2685505 https://reactome.org/PathwayBrowser/#/R-XTR-2685505 TPCN1/2 transport lysosomal Ca2+ to cytosol IEA Xenopus tropicalis 2453 R-GGA-433576 https://reactome.org/PathwayBrowser/#/R-GGA-433576 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ IEA Gallus gallus 2453 R-GGA-433592 https://reactome.org/PathwayBrowser/#/R-GGA-433592 sphinganine + stearyl-CoA => dihydroceramide + CoASH IEA Gallus gallus 2453 R-GGA-433606 https://reactome.org/PathwayBrowser/#/R-GGA-433606 sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP IEA Gallus gallus 2461 R-BTA-9701147 https://reactome.org/PathwayBrowser/#/R-BTA-9701147 TRPV1 binds TRPV1 blockers IEA Bos taurus 2461 R-CEL-9701147 https://reactome.org/PathwayBrowser/#/R-CEL-9701147 TRPV1 binds TRPV1 blockers IEA Caenorhabditis elegans 2461 R-CFA-9701147 https://reactome.org/PathwayBrowser/#/R-CFA-9701147 TRPV1 binds TRPV1 blockers IEA Canis familiaris 2461 R-DME-9701147 https://reactome.org/PathwayBrowser/#/R-DME-9701147 TRPV1 binds TRPV1 blockers IEA Drosophila melanogaster 2461 R-DRE-9701147 https://reactome.org/PathwayBrowser/#/R-DRE-9701147 TRPV1 binds TRPV1 blockers IEA Danio rerio 2461 R-GGA-9701147 https://reactome.org/PathwayBrowser/#/R-GGA-9701147 TRPV1 binds TRPV1 blockers IEA Gallus gallus 2461 R-HSA-9701147 https://reactome.org/PathwayBrowser/#/R-HSA-9701147 TRPV1 binds TRPV1 blockers TAS Homo sapiens 2461 R-MMU-9701147 https://reactome.org/PathwayBrowser/#/R-MMU-9701147 TRPV1 binds TRPV1 blockers IEA Mus musculus 2461 R-RNO-9701147 https://reactome.org/PathwayBrowser/#/R-RNO-9701147 TRPV1 binds TRPV1 blockers IEA Rattus norvegicus 2461 R-SCE-9701147 https://reactome.org/PathwayBrowser/#/R-SCE-9701147 TRPV1 binds TRPV1 blockers IEA Saccharomyces cerevisiae 2461 R-SSC-9701147 https://reactome.org/PathwayBrowser/#/R-SSC-9701147 TRPV1 binds TRPV1 blockers IEA Sus scrofa 2461 R-XTR-9701147 https://reactome.org/PathwayBrowser/#/R-XTR-9701147 TRPV1 binds TRPV1 blockers IEA Xenopus tropicalis 2467 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 2467 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 2467 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 2467 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 2467 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 2467 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 2467 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 2467 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 2467 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 2469 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 2469 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 2469 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 2469 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 2469 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 2469 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 2469 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 2469 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 2469 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 2486 R-BTA-9701064 https://reactome.org/PathwayBrowser/#/R-BTA-9701064 TRPV1 binds TRPV1 agonists IEA Bos taurus 2486 R-CEL-9701064 https://reactome.org/PathwayBrowser/#/R-CEL-9701064 TRPV1 binds TRPV1 agonists IEA Caenorhabditis elegans 2486 R-CFA-9701064 https://reactome.org/PathwayBrowser/#/R-CFA-9701064 TRPV1 binds TRPV1 agonists IEA Canis familiaris 2486 R-DME-9701064 https://reactome.org/PathwayBrowser/#/R-DME-9701064 TRPV1 binds TRPV1 agonists IEA Drosophila melanogaster 2486 R-DRE-9701064 https://reactome.org/PathwayBrowser/#/R-DRE-9701064 TRPV1 binds TRPV1 agonists IEA Danio rerio 2486 R-GGA-9701064 https://reactome.org/PathwayBrowser/#/R-GGA-9701064 TRPV1 binds TRPV1 agonists IEA Gallus gallus 2486 R-HSA-9701064 https://reactome.org/PathwayBrowser/#/R-HSA-9701064 TRPV1 binds TRPV1 agonists TAS Homo sapiens 2486 R-MMU-9701064 https://reactome.org/PathwayBrowser/#/R-MMU-9701064 TRPV1 binds TRPV1 agonists IEA Mus musculus 2486 R-RNO-9701064 https://reactome.org/PathwayBrowser/#/R-RNO-9701064 TRPV1 binds TRPV1 agonists IEA Rattus norvegicus 2486 R-SCE-9701064 https://reactome.org/PathwayBrowser/#/R-SCE-9701064 TRPV1 binds TRPV1 agonists IEA Saccharomyces cerevisiae 2486 R-SSC-9701064 https://reactome.org/PathwayBrowser/#/R-SSC-9701064 TRPV1 binds TRPV1 agonists IEA Sus scrofa 2486 R-XTR-9701064 https://reactome.org/PathwayBrowser/#/R-XTR-9701064 TRPV1 binds TRPV1 agonists IEA Xenopus tropicalis 2488 R-BTA-9701064 https://reactome.org/PathwayBrowser/#/R-BTA-9701064 TRPV1 binds TRPV1 agonists IEA Bos taurus 2488 R-CEL-9701064 https://reactome.org/PathwayBrowser/#/R-CEL-9701064 TRPV1 binds TRPV1 agonists IEA Caenorhabditis elegans 2488 R-CFA-9701064 https://reactome.org/PathwayBrowser/#/R-CFA-9701064 TRPV1 binds TRPV1 agonists IEA Canis familiaris 2488 R-DME-9701064 https://reactome.org/PathwayBrowser/#/R-DME-9701064 TRPV1 binds TRPV1 agonists IEA Drosophila melanogaster 2488 R-DRE-9701064 https://reactome.org/PathwayBrowser/#/R-DRE-9701064 TRPV1 binds TRPV1 agonists IEA Danio rerio 2488 R-GGA-9701064 https://reactome.org/PathwayBrowser/#/R-GGA-9701064 TRPV1 binds TRPV1 agonists IEA Gallus gallus 2488 R-HSA-9701064 https://reactome.org/PathwayBrowser/#/R-HSA-9701064 TRPV1 binds TRPV1 agonists TAS Homo sapiens 2488 R-MMU-9701064 https://reactome.org/PathwayBrowser/#/R-MMU-9701064 TRPV1 binds TRPV1 agonists IEA Mus musculus 2488 R-RNO-9701064 https://reactome.org/PathwayBrowser/#/R-RNO-9701064 TRPV1 binds TRPV1 agonists IEA Rattus norvegicus 2488 R-SCE-9701064 https://reactome.org/PathwayBrowser/#/R-SCE-9701064 TRPV1 binds TRPV1 agonists IEA Saccharomyces cerevisiae 2488 R-SSC-9701064 https://reactome.org/PathwayBrowser/#/R-SSC-9701064 TRPV1 binds TRPV1 agonists IEA Sus scrofa 2488 R-XTR-9701064 https://reactome.org/PathwayBrowser/#/R-XTR-9701064 TRPV1 binds TRPV1 agonists IEA Xenopus tropicalis 2491 R-BTA-9701064 https://reactome.org/PathwayBrowser/#/R-BTA-9701064 TRPV1 binds TRPV1 agonists IEA Bos taurus 2491 R-CEL-9701064 https://reactome.org/PathwayBrowser/#/R-CEL-9701064 TRPV1 binds TRPV1 agonists IEA Caenorhabditis elegans 2491 R-CFA-9701064 https://reactome.org/PathwayBrowser/#/R-CFA-9701064 TRPV1 binds TRPV1 agonists IEA Canis familiaris 2491 R-DME-9701064 https://reactome.org/PathwayBrowser/#/R-DME-9701064 TRPV1 binds TRPV1 agonists IEA Drosophila melanogaster 2491 R-DRE-9701064 https://reactome.org/PathwayBrowser/#/R-DRE-9701064 TRPV1 binds TRPV1 agonists IEA Danio rerio 2491 R-GGA-9701064 https://reactome.org/PathwayBrowser/#/R-GGA-9701064 TRPV1 binds TRPV1 agonists IEA Gallus gallus 2491 R-HSA-9701064 https://reactome.org/PathwayBrowser/#/R-HSA-9701064 TRPV1 binds TRPV1 agonists TAS Homo sapiens 2491 R-MMU-9701064 https://reactome.org/PathwayBrowser/#/R-MMU-9701064 TRPV1 binds TRPV1 agonists IEA Mus musculus 2491 R-RNO-9701064 https://reactome.org/PathwayBrowser/#/R-RNO-9701064 TRPV1 binds TRPV1 agonists IEA Rattus norvegicus 2491 R-SCE-9701064 https://reactome.org/PathwayBrowser/#/R-SCE-9701064 TRPV1 binds TRPV1 agonists IEA Saccharomyces cerevisiae 2491 R-SSC-9701064 https://reactome.org/PathwayBrowser/#/R-SSC-9701064 TRPV1 binds TRPV1 agonists IEA Sus scrofa 2491 R-XTR-9701064 https://reactome.org/PathwayBrowser/#/R-XTR-9701064 TRPV1 binds TRPV1 agonists IEA Xenopus tropicalis 2508 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 2508 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 2508 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 2508 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 2508 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 2508 R-BTA-6814797 https://reactome.org/PathwayBrowser/#/R-BTA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Bos taurus 2508 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 2508 R-BTA-8952251 https://reactome.org/PathwayBrowser/#/R-BTA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Bos taurus 2508 R-CEL-6814797 https://reactome.org/PathwayBrowser/#/R-CEL-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Caenorhabditis elegans 2508 R-CEL-8952251 https://reactome.org/PathwayBrowser/#/R-CEL-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Caenorhabditis elegans 2508 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 2508 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 2508 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 2508 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 2508 R-CFA-6814797 https://reactome.org/PathwayBrowser/#/R-CFA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Canis familiaris 2508 R-CFA-8952251 https://reactome.org/PathwayBrowser/#/R-CFA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Canis familiaris 2508 R-DDI-6814797 https://reactome.org/PathwayBrowser/#/R-DDI-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Dictyostelium discoideum 2508 R-DME-8952251 https://reactome.org/PathwayBrowser/#/R-DME-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Drosophila melanogaster 2508 R-DRE-6814797 https://reactome.org/PathwayBrowser/#/R-DRE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Danio rerio 2508 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 2508 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 2508 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 2508 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 2508 R-GGA-6814797 https://reactome.org/PathwayBrowser/#/R-GGA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Gallus gallus 2508 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 2508 R-GGA-8952251 https://reactome.org/PathwayBrowser/#/R-GGA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Gallus gallus 2508 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 2508 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 2508 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 2508 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 2508 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 2508 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 2508 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 2508 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 2508 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 2508 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 2508 R-HSA-6814797 https://reactome.org/PathwayBrowser/#/R-HSA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine TAS Homo sapiens 2508 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 2508 R-HSA-8952251 https://reactome.org/PathwayBrowser/#/R-HSA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) TAS Homo sapiens 2508 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 2508 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 2508 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 2508 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 2508 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 2508 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 2508 R-MMU-6814797 https://reactome.org/PathwayBrowser/#/R-MMU-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Mus musculus 2508 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 2508 R-MMU-8952251 https://reactome.org/PathwayBrowser/#/R-MMU-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Mus musculus 2508 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 2508 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 2508 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 2508 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 2508 R-RNO-6814797 https://reactome.org/PathwayBrowser/#/R-RNO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Rattus norvegicus 2508 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 2508 R-RNO-8952251 https://reactome.org/PathwayBrowser/#/R-RNO-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Rattus norvegicus 2508 R-SCE-6814797 https://reactome.org/PathwayBrowser/#/R-SCE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Saccharomyces cerevisiae 2508 R-SCE-8952251 https://reactome.org/PathwayBrowser/#/R-SCE-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Saccharomyces cerevisiae 2508 R-SPO-6814797 https://reactome.org/PathwayBrowser/#/R-SPO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Schizosaccharomyces pombe 2508 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 2508 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 2508 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 2508 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 2508 R-SSC-6814797 https://reactome.org/PathwayBrowser/#/R-SSC-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Sus scrofa 2508 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 2508 R-SSC-8952251 https://reactome.org/PathwayBrowser/#/R-SSC-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Sus scrofa 2508 R-XTR-6814797 https://reactome.org/PathwayBrowser/#/R-XTR-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Xenopus tropicalis 2508 R-XTR-8952251 https://reactome.org/PathwayBrowser/#/R-XTR-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Xenopus tropicalis 2509 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 2509 R-BTA-418436 https://reactome.org/PathwayBrowser/#/R-BTA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Bos taurus 2509 R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 2509 R-BTA-9012374 https://reactome.org/PathwayBrowser/#/R-BTA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Bos taurus 2509 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 2509 R-BTA-9621179 https://reactome.org/PathwayBrowser/#/R-BTA-9621179 Cinaciguat binds sGC:NO IEA Bos taurus 2509 R-BTA-9854368 https://reactome.org/PathwayBrowser/#/R-BTA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Bos taurus 2509 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 2509 R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 2509 R-CEL-9012374 https://reactome.org/PathwayBrowser/#/R-CEL-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Caenorhabditis elegans 2509 R-CEL-9854368 https://reactome.org/PathwayBrowser/#/R-CEL-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Caenorhabditis elegans 2509 R-CFA-418436 https://reactome.org/PathwayBrowser/#/R-CFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Canis familiaris 2509 R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 2509 R-CFA-9012374 https://reactome.org/PathwayBrowser/#/R-CFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Canis familiaris 2509 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 2509 R-CFA-9621179 https://reactome.org/PathwayBrowser/#/R-CFA-9621179 Cinaciguat binds sGC:NO IEA Canis familiaris 2509 R-CFA-9854368 https://reactome.org/PathwayBrowser/#/R-CFA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Canis familiaris 2509 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 2509 R-DDI-418436 https://reactome.org/PathwayBrowser/#/R-DDI-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Dictyostelium discoideum 2509 R-DDI-9012374 https://reactome.org/PathwayBrowser/#/R-DDI-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Dictyostelium discoideum 2509 R-DDI-9854368 https://reactome.org/PathwayBrowser/#/R-DDI-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Dictyostelium discoideum 2509 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 2509 R-DME-418436 https://reactome.org/PathwayBrowser/#/R-DME-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Drosophila melanogaster 2509 R-DME-9012374 https://reactome.org/PathwayBrowser/#/R-DME-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Drosophila melanogaster 2509 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 2509 R-DME-9621179 https://reactome.org/PathwayBrowser/#/R-DME-9621179 Cinaciguat binds sGC:NO IEA Drosophila melanogaster 2509 R-DME-9854368 https://reactome.org/PathwayBrowser/#/R-DME-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Drosophila melanogaster 2509 R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio 2509 R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 2509 R-DRE-9012374 https://reactome.org/PathwayBrowser/#/R-DRE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Danio rerio 2509 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 2509 R-DRE-9621179 https://reactome.org/PathwayBrowser/#/R-DRE-9621179 Cinaciguat binds sGC:NO IEA Danio rerio 2509 R-DRE-9854368 https://reactome.org/PathwayBrowser/#/R-DRE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Danio rerio 2509 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 2509 R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus 2509 R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 2509 R-GGA-9012374 https://reactome.org/PathwayBrowser/#/R-GGA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Gallus gallus 2509 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 2509 R-GGA-9621179 https://reactome.org/PathwayBrowser/#/R-GGA-9621179 Cinaciguat binds sGC:NO IEA Gallus gallus 2509 R-GGA-9854368 https://reactome.org/PathwayBrowser/#/R-GGA-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Gallus gallus 2509 R-HSA-1222407 https://reactome.org/PathwayBrowser/#/R-HSA-1222407 Superoxide and nitric oxide react to peroxynitrite TAS Homo sapiens 2509 R-HSA-1222512 https://reactome.org/PathwayBrowser/#/R-HSA-1222512 Nitric oxide oxidizes to nitrosyl ion TAS Homo sapiens 2509 R-HSA-1222662 https://reactome.org/PathwayBrowser/#/R-HSA-1222662 Nitric oxide enters the bacterium TAS Homo sapiens 2509 R-HSA-1222686 https://reactome.org/PathwayBrowser/#/R-HSA-1222686 Nitric oxide diffuses into the phagosome TAS Homo sapiens 2509 R-HSA-1497878 https://reactome.org/PathwayBrowser/#/R-HSA-1497878 Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-) TAS Homo sapiens 2509 R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 2509 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 2509 R-HSA-3697855 https://reactome.org/PathwayBrowser/#/R-HSA-3697855 Superoxide and nitric oxide react to form peroxynitrite in mitochondria TAS Homo sapiens 2509 R-HSA-392143 https://reactome.org/PathwayBrowser/#/R-HSA-392143 NO binds to Guanylate Cyclase IEA Homo sapiens 2509 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 2509 R-HSA-418436 https://reactome.org/PathwayBrowser/#/R-HSA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) TAS Homo sapiens 2509 R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 2509 R-HSA-6803989 https://reactome.org/PathwayBrowser/#/R-HSA-6803989 Nitric oxide and O2 react to NO2 TAS Homo sapiens 2509 R-HSA-6804006 https://reactome.org/PathwayBrowser/#/R-HSA-6804006 NO and NO2 react to N2O3 TAS Homo sapiens 2509 R-HSA-8942052 https://reactome.org/PathwayBrowser/#/R-HSA-8942052 Superoxide and nitric oxide react to peroxynitrite in the phagosome TAS Homo sapiens 2509 R-HSA-9012374 https://reactome.org/PathwayBrowser/#/R-HSA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space TAS Homo sapiens 2509 R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 2509 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 2509 R-HSA-9621179 https://reactome.org/PathwayBrowser/#/R-HSA-9621179 Cinaciguat binds sGC:NO TAS Homo sapiens 2509 R-HSA-9709885 https://reactome.org/PathwayBrowser/#/R-HSA-9709885 BIL scavenges NO TAS Homo sapiens 2509 R-HSA-9854368 https://reactome.org/PathwayBrowser/#/R-HSA-9854368 ROS,RNS oxidize ACO2:4Fe-4S TAS Homo sapiens 2509 R-HSA-9941244 https://reactome.org/PathwayBrowser/#/R-HSA-9941244 ROS/RNS degrade HA TAS Homo sapiens 2509 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 2509 R-MMU-418436 https://reactome.org/PathwayBrowser/#/R-MMU-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Mus musculus 2509 R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 2509 R-MMU-9012374 https://reactome.org/PathwayBrowser/#/R-MMU-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Mus musculus 2509 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 2509 R-MMU-9621179 https://reactome.org/PathwayBrowser/#/R-MMU-9621179 Cinaciguat binds sGC:NO IEA Mus musculus 2509 R-MMU-9854368 https://reactome.org/PathwayBrowser/#/R-MMU-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Mus musculus 2509 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 2509 R-PFA-418436 https://reactome.org/PathwayBrowser/#/R-PFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Plasmodium falciparum 2509 R-PFA-9012374 https://reactome.org/PathwayBrowser/#/R-PFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Plasmodium falciparum 2509 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 2509 R-RNO-418436 https://reactome.org/PathwayBrowser/#/R-RNO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Rattus norvegicus 2509 R-RNO-427279 https://reactome.org/PathwayBrowser/#/R-RNO-427279 NO binds to Guanylate Cyclase TAS Rattus norvegicus 2509 R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 2509 R-RNO-9012374 https://reactome.org/PathwayBrowser/#/R-RNO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Rattus norvegicus 2509 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 2509 R-RNO-9621179 https://reactome.org/PathwayBrowser/#/R-RNO-9621179 Cinaciguat binds sGC:NO IEA Rattus norvegicus 2509 R-RNO-9854368 https://reactome.org/PathwayBrowser/#/R-RNO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Rattus norvegicus 2509 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 2509 R-SCE-418436 https://reactome.org/PathwayBrowser/#/R-SCE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Saccharomyces cerevisiae 2509 R-SCE-9012374 https://reactome.org/PathwayBrowser/#/R-SCE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Saccharomyces cerevisiae 2509 R-SCE-9854368 https://reactome.org/PathwayBrowser/#/R-SCE-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Saccharomyces cerevisiae 2509 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 2509 R-SPO-418436 https://reactome.org/PathwayBrowser/#/R-SPO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Schizosaccharomyces pombe 2509 R-SPO-9012374 https://reactome.org/PathwayBrowser/#/R-SPO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Schizosaccharomyces pombe 2509 R-SPO-9854368 https://reactome.org/PathwayBrowser/#/R-SPO-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Schizosaccharomyces pombe 2509 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 2509 R-SSC-418436 https://reactome.org/PathwayBrowser/#/R-SSC-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Sus scrofa 2509 R-SSC-5340226 https://reactome.org/PathwayBrowser/#/R-SSC-5340226 CYGB dioxygenates NO IEA Sus scrofa 2509 R-SSC-9012374 https://reactome.org/PathwayBrowser/#/R-SSC-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Sus scrofa 2509 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 2509 R-SSC-9621179 https://reactome.org/PathwayBrowser/#/R-SSC-9621179 Cinaciguat binds sGC:NO IEA Sus scrofa 2509 R-SSC-9854368 https://reactome.org/PathwayBrowser/#/R-SSC-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Sus scrofa 2509 R-XTR-5340226 https://reactome.org/PathwayBrowser/#/R-XTR-5340226 CYGB dioxygenates NO IEA Xenopus tropicalis 2509 R-XTR-9012374 https://reactome.org/PathwayBrowser/#/R-XTR-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Xenopus tropicalis 2509 R-XTR-9854368 https://reactome.org/PathwayBrowser/#/R-XTR-9854368 ROS,RNS oxidize ACO2:4Fe-4S IEA Xenopus tropicalis 2510 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 2510 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2510 R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 2510 R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 2510 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2510 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2510 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 2510 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 2510 R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 2510 R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 2510 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 2510 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2510 R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 2510 R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 2510 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2510 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2510 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 2510 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 2510 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 2510 R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 2510 R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 2510 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 2510 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2510 R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 2510 R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 2510 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 2510 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 2510 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2510 R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 2510 R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 2510 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2510 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2510 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 2510 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 2510 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 2510 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2510 R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 2510 R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 2510 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2510 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2510 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 2510 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 2510 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 2510 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 2510 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 2510 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2510 R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 2510 R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 2510 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2510 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2510 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 2510 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 2510 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 2510 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 2510 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2510 R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 2510 R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 2510 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 2510 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 2510 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 2510 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 2510 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2510 R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 2510 R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 2510 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2510 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2510 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 2510 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 2510 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 2510 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2510 R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 2510 R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 2510 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2510 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2514 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2514 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2514 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2514 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2514 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2514 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2514 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2514 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2514 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2514 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 2519 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2519 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2519 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2519 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2519 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2519 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2519 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2519 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2519 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2519 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 2522 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 2522 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 2522 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 2522 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 2522 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 2523 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2523 R-BTA-9725855 https://reactome.org/PathwayBrowser/#/R-BTA-9725855 NR3C2 binds NR3C2 antagonists IEA Bos taurus 2523 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2523 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2523 R-CFA-9725855 https://reactome.org/PathwayBrowser/#/R-CFA-9725855 NR3C2 binds NR3C2 antagonists IEA Canis familiaris 2523 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2523 R-DME-9725855 https://reactome.org/PathwayBrowser/#/R-DME-9725855 NR3C2 binds NR3C2 antagonists IEA Drosophila melanogaster 2523 R-DRE-9725855 https://reactome.org/PathwayBrowser/#/R-DRE-9725855 NR3C2 binds NR3C2 antagonists IEA Danio rerio 2523 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2523 R-GGA-9725855 https://reactome.org/PathwayBrowser/#/R-GGA-9725855 NR3C2 binds NR3C2 antagonists IEA Gallus gallus 2523 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2523 R-HSA-9725855 https://reactome.org/PathwayBrowser/#/R-HSA-9725855 NR3C2 binds NR3C2 antagonists TAS Homo sapiens 2523 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2523 R-MMU-9725855 https://reactome.org/PathwayBrowser/#/R-MMU-9725855 NR3C2 binds NR3C2 antagonists IEA Mus musculus 2523 R-PFA-9725855 https://reactome.org/PathwayBrowser/#/R-PFA-9725855 NR3C2 binds NR3C2 antagonists IEA Plasmodium falciparum 2523 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2523 R-RNO-9725855 https://reactome.org/PathwayBrowser/#/R-RNO-9725855 NR3C2 binds NR3C2 antagonists IEA Rattus norvegicus 2523 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2523 R-SSC-9725855 https://reactome.org/PathwayBrowser/#/R-SSC-9725855 NR3C2 binds NR3C2 antagonists IEA Sus scrofa 2523 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 2523 R-XTR-9725855 https://reactome.org/PathwayBrowser/#/R-XTR-9725855 NR3C2 binds NR3C2 antagonists IEA Xenopus tropicalis 2524 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2524 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2524 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2524 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2524 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2524 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2524 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2524 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2524 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2524 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 2559 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 2559 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 2559 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 2559 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 2559 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 2559 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 2559 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 2559 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 2559 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 2559 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 2566 R-BTA-9613570 https://reactome.org/PathwayBrowser/#/R-BTA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Bos taurus 2566 R-CEL-9613570 https://reactome.org/PathwayBrowser/#/R-CEL-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Caenorhabditis elegans 2566 R-CFA-9613570 https://reactome.org/PathwayBrowser/#/R-CFA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Canis familiaris 2566 R-DME-9613570 https://reactome.org/PathwayBrowser/#/R-DME-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Drosophila melanogaster 2566 R-GGA-9613570 https://reactome.org/PathwayBrowser/#/R-GGA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Gallus gallus 2566 R-HSA-9613570 https://reactome.org/PathwayBrowser/#/R-HSA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers TAS Homo sapiens 2566 R-MMU-9613570 https://reactome.org/PathwayBrowser/#/R-MMU-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Mus musculus 2566 R-PFA-9613570 https://reactome.org/PathwayBrowser/#/R-PFA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Plasmodium falciparum 2566 R-RNO-9613570 https://reactome.org/PathwayBrowser/#/R-RNO-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Rattus norvegicus 2566 R-SSC-9613570 https://reactome.org/PathwayBrowser/#/R-SSC-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Sus scrofa 2566 R-XTR-9613570 https://reactome.org/PathwayBrowser/#/R-XTR-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Xenopus tropicalis 2568 R-BTA-9678766 https://reactome.org/PathwayBrowser/#/R-BTA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Bos taurus 2568 R-CFA-9678766 https://reactome.org/PathwayBrowser/#/R-CFA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Canis familiaris 2568 R-DRE-9678766 https://reactome.org/PathwayBrowser/#/R-DRE-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Danio rerio 2568 R-GGA-9678766 https://reactome.org/PathwayBrowser/#/R-GGA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Gallus gallus 2568 R-HSA-9678766 https://reactome.org/PathwayBrowser/#/R-HSA-9678766 CYP3A4 binds CYP3A4 inhibitors TAS Homo sapiens 2568 R-MMU-9678766 https://reactome.org/PathwayBrowser/#/R-MMU-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Mus musculus 2568 R-RNO-9678766 https://reactome.org/PathwayBrowser/#/R-RNO-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Rattus norvegicus 2568 R-SSC-9678766 https://reactome.org/PathwayBrowser/#/R-SSC-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Sus scrofa 2568 R-XTR-9678766 https://reactome.org/PathwayBrowser/#/R-XTR-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Xenopus tropicalis 2585 R-BTA-174916 https://reactome.org/PathwayBrowser/#/R-BTA-174916 Formation of N-glucuronides IEA Bos taurus 2585 R-DDI-174916 https://reactome.org/PathwayBrowser/#/R-DDI-174916 Formation of N-glucuronides IEA Dictyostelium discoideum 2585 R-GGA-174916 https://reactome.org/PathwayBrowser/#/R-GGA-174916 Formation of N-glucuronides IEA Gallus gallus 2585 R-HSA-174916 https://reactome.org/PathwayBrowser/#/R-HSA-174916 Formation of N-glucuronides TAS Homo sapiens 2585 R-MMU-174916 https://reactome.org/PathwayBrowser/#/R-MMU-174916 Formation of N-glucuronides IEA Mus musculus 2585 R-RNO-174916 https://reactome.org/PathwayBrowser/#/R-RNO-174916 Formation of N-glucuronides IEA Rattus norvegicus 2585 R-SSC-174916 https://reactome.org/PathwayBrowser/#/R-SSC-174916 Formation of N-glucuronides IEA Sus scrofa 2593 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 2593 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 2593 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 2593 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 2593 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 2593 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 2593 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 2593 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 2593 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 2593 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 2593 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 2593 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 2593 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 2593 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 2593 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 2593 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 2593 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 2593 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 260 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 260 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 260 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 260 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 260 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 260 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 260 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 2603 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 2603 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 2603 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 2603 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 2603 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 2603 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 2603 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 2603 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 2604 R-BTA-9613264 https://reactome.org/PathwayBrowser/#/R-BTA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Bos taurus 2604 R-CFA-9613264 https://reactome.org/PathwayBrowser/#/R-CFA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Canis familiaris 2604 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus 2604 R-HSA-9613264 https://reactome.org/PathwayBrowser/#/R-HSA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE TAS Homo sapiens 2604 R-MMU-9613264 https://reactome.org/PathwayBrowser/#/R-MMU-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Mus musculus 2604 R-RNO-9613264 https://reactome.org/PathwayBrowser/#/R-RNO-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Rattus norvegicus 2604 R-SSC-9613264 https://reactome.org/PathwayBrowser/#/R-SSC-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Sus scrofa 2605 R-BTA-9613264 https://reactome.org/PathwayBrowser/#/R-BTA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Bos taurus 2605 R-CFA-9613264 https://reactome.org/PathwayBrowser/#/R-CFA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Canis familiaris 2605 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus 2605 R-HSA-9613264 https://reactome.org/PathwayBrowser/#/R-HSA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE TAS Homo sapiens 2605 R-MMU-9613264 https://reactome.org/PathwayBrowser/#/R-MMU-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Mus musculus 2605 R-RNO-9613264 https://reactome.org/PathwayBrowser/#/R-RNO-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Rattus norvegicus 2605 R-SSC-9613264 https://reactome.org/PathwayBrowser/#/R-SSC-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Sus scrofa 2608 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 2608 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 2608 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 2608 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 2608 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 2608 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 2608 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 2608 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 2624 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 2624 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 2624 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 2624 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 2624 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 2624 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 2624 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 2624 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 2624 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 2644 R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A transfers PALM to CAR IEA Bos taurus 2644 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 2644 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 2644 R-BTA-5246478 https://reactome.org/PathwayBrowser/#/R-BTA-5246478 APOM binds retinoids IEA Bos taurus 2644 R-BTA-5334827 https://reactome.org/PathwayBrowser/#/R-BTA-5334827 SUMO-CRABP2 binds atRA IEA Bos taurus 2644 R-BTA-5334854 https://reactome.org/PathwayBrowser/#/R-BTA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Bos taurus 2644 R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 2644 R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 2644 R-BTA-5422942 https://reactome.org/PathwayBrowser/#/R-BTA-5422942 RXRA:PPARD binds FABP5:atRA IEA Bos taurus 2644 R-BTA-5622129 https://reactome.org/PathwayBrowser/#/R-BTA-5622129 FABP5 binds atRA IEA Bos taurus 2644 R-BTA-5622134 https://reactome.org/PathwayBrowser/#/R-BTA-5622134 CRABP1 binds atRA IEA Bos taurus 2644 R-BTA-5633256 https://reactome.org/PathwayBrowser/#/R-BTA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Bos taurus 2644 R-BTA-5634100 https://reactome.org/PathwayBrowser/#/R-BTA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Bos taurus 2644 R-BTA-5634103 https://reactome.org/PathwayBrowser/#/R-BTA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Bos taurus 2644 R-BTA-5634104 https://reactome.org/PathwayBrowser/#/R-BTA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Bos taurus 2644 R-BTA-8869568 https://reactome.org/PathwayBrowser/#/R-BTA-8869568 NPM1 binds TFAP2A homodimer IEA Bos taurus 2644 R-BTA-9617067 https://reactome.org/PathwayBrowser/#/R-BTA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Bos taurus 2644 R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A transfers PALM to CAR IEA Caenorhabditis elegans 2644 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 2644 R-CEL-5334827 https://reactome.org/PathwayBrowser/#/R-CEL-5334827 SUMO-CRABP2 binds atRA IEA Caenorhabditis elegans 2644 R-CEL-5334854 https://reactome.org/PathwayBrowser/#/R-CEL-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Caenorhabditis elegans 2644 R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 2644 R-CEL-5422942 https://reactome.org/PathwayBrowser/#/R-CEL-5422942 RXRA:PPARD binds FABP5:atRA IEA Caenorhabditis elegans 2644 R-CEL-5622129 https://reactome.org/PathwayBrowser/#/R-CEL-5622129 FABP5 binds atRA IEA Caenorhabditis elegans 2644 R-CEL-5622134 https://reactome.org/PathwayBrowser/#/R-CEL-5622134 CRABP1 binds atRA IEA Caenorhabditis elegans 2644 R-CEL-5633256 https://reactome.org/PathwayBrowser/#/R-CEL-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Caenorhabditis elegans 2644 R-CEL-5634100 https://reactome.org/PathwayBrowser/#/R-CEL-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Caenorhabditis elegans 2644 R-CEL-5634103 https://reactome.org/PathwayBrowser/#/R-CEL-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Caenorhabditis elegans 2644 R-CEL-5634104 https://reactome.org/PathwayBrowser/#/R-CEL-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Caenorhabditis elegans 2644 R-CEL-9617067 https://reactome.org/PathwayBrowser/#/R-CEL-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Caenorhabditis elegans 2644 R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A transfers PALM to CAR IEA Canis familiaris 2644 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 2644 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 2644 R-CFA-5246478 https://reactome.org/PathwayBrowser/#/R-CFA-5246478 APOM binds retinoids IEA Canis familiaris 2644 R-CFA-5334827 https://reactome.org/PathwayBrowser/#/R-CFA-5334827 SUMO-CRABP2 binds atRA IEA Canis familiaris 2644 R-CFA-5334854 https://reactome.org/PathwayBrowser/#/R-CFA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Canis familiaris 2644 R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 2644 R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 2644 R-CFA-5422942 https://reactome.org/PathwayBrowser/#/R-CFA-5422942 RXRA:PPARD binds FABP5:atRA IEA Canis familiaris 2644 R-CFA-5622129 https://reactome.org/PathwayBrowser/#/R-CFA-5622129 FABP5 binds atRA IEA Canis familiaris 2644 R-CFA-5622134 https://reactome.org/PathwayBrowser/#/R-CFA-5622134 CRABP1 binds atRA IEA Canis familiaris 2644 R-CFA-5633256 https://reactome.org/PathwayBrowser/#/R-CFA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Canis familiaris 2644 R-CFA-5634100 https://reactome.org/PathwayBrowser/#/R-CFA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Canis familiaris 2644 R-CFA-5634103 https://reactome.org/PathwayBrowser/#/R-CFA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Canis familiaris 2644 R-CFA-5634104 https://reactome.org/PathwayBrowser/#/R-CFA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Canis familiaris 2644 R-CFA-8869568 https://reactome.org/PathwayBrowser/#/R-CFA-8869568 NPM1 binds TFAP2A homodimer IEA Canis familiaris 2644 R-CFA-9617067 https://reactome.org/PathwayBrowser/#/R-CFA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Canis familiaris 2644 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 2644 R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 2644 R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A transfers PALM to CAR IEA Drosophila melanogaster 2644 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 2644 R-DME-5334827 https://reactome.org/PathwayBrowser/#/R-DME-5334827 SUMO-CRABP2 binds atRA IEA Drosophila melanogaster 2644 R-DME-5334854 https://reactome.org/PathwayBrowser/#/R-DME-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Drosophila melanogaster 2644 R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 2644 R-DME-5622134 https://reactome.org/PathwayBrowser/#/R-DME-5622134 CRABP1 binds atRA IEA Drosophila melanogaster 2644 R-DME-5634103 https://reactome.org/PathwayBrowser/#/R-DME-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Drosophila melanogaster 2644 R-DME-5634104 https://reactome.org/PathwayBrowser/#/R-DME-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Drosophila melanogaster 2644 R-DME-8869568 https://reactome.org/PathwayBrowser/#/R-DME-8869568 NPM1 binds TFAP2A homodimer IEA Drosophila melanogaster 2644 R-DME-9617067 https://reactome.org/PathwayBrowser/#/R-DME-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Drosophila melanogaster 2644 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 2644 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 2644 R-DRE-5334827 https://reactome.org/PathwayBrowser/#/R-DRE-5334827 SUMO-CRABP2 binds atRA IEA Danio rerio 2644 R-DRE-5334854 https://reactome.org/PathwayBrowser/#/R-DRE-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Danio rerio 2644 R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 2644 R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 2644 R-DRE-5622134 https://reactome.org/PathwayBrowser/#/R-DRE-5622134 CRABP1 binds atRA IEA Danio rerio 2644 R-DRE-5634103 https://reactome.org/PathwayBrowser/#/R-DRE-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Danio rerio 2644 R-DRE-5634104 https://reactome.org/PathwayBrowser/#/R-DRE-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Danio rerio 2644 R-DRE-9617067 https://reactome.org/PathwayBrowser/#/R-DRE-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Danio rerio 2644 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A transfers PALM to CAR IEA Gallus gallus 2644 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 2644 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 2644 R-GGA-5334827 https://reactome.org/PathwayBrowser/#/R-GGA-5334827 SUMO-CRABP2 binds atRA IEA Gallus gallus 2644 R-GGA-5334854 https://reactome.org/PathwayBrowser/#/R-GGA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Gallus gallus 2644 R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 2644 R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 2644 R-GGA-5422942 https://reactome.org/PathwayBrowser/#/R-GGA-5422942 RXRA:PPARD binds FABP5:atRA IEA Gallus gallus 2644 R-GGA-5622129 https://reactome.org/PathwayBrowser/#/R-GGA-5622129 FABP5 binds atRA IEA Gallus gallus 2644 R-GGA-5622134 https://reactome.org/PathwayBrowser/#/R-GGA-5622134 CRABP1 binds atRA IEA Gallus gallus 2644 R-GGA-5633256 https://reactome.org/PathwayBrowser/#/R-GGA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Gallus gallus 2644 R-GGA-5634100 https://reactome.org/PathwayBrowser/#/R-GGA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Gallus gallus 2644 R-GGA-5634103 https://reactome.org/PathwayBrowser/#/R-GGA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Gallus gallus 2644 R-GGA-5634104 https://reactome.org/PathwayBrowser/#/R-GGA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Gallus gallus 2644 R-GGA-8869568 https://reactome.org/PathwayBrowser/#/R-GGA-8869568 NPM1 binds TFAP2A homodimer IEA Gallus gallus 2644 R-GGA-9617067 https://reactome.org/PathwayBrowser/#/R-GGA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Gallus gallus 2644 R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A transfers PALM to CAR TAS Homo sapiens 2644 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 2644 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 2644 R-HSA-5246478 https://reactome.org/PathwayBrowser/#/R-HSA-5246478 APOM binds retinoids TAS Homo sapiens 2644 R-HSA-5334827 https://reactome.org/PathwayBrowser/#/R-HSA-5334827 SUMO-CRABP2 binds atRA TAS Homo sapiens 2644 R-HSA-5334854 https://reactome.org/PathwayBrowser/#/R-HSA-5334854 RAR:RXR binds SUMO-CRABP2:atRA TAS Homo sapiens 2644 R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 2644 R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 2644 R-HSA-5422942 https://reactome.org/PathwayBrowser/#/R-HSA-5422942 RXRA:PPARD binds FABP5:atRA TAS Homo sapiens 2644 R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 2644 R-HSA-5617431 https://reactome.org/PathwayBrowser/#/R-HSA-5617431 Retinoic acid activates HOXA1 chromatin IEA Homo sapiens 2644 R-HSA-5617445 https://reactome.org/PathwayBrowser/#/R-HSA-5617445 HOXD1 chromatin is activated IEA Homo sapiens 2644 R-HSA-5617452 https://reactome.org/PathwayBrowser/#/R-HSA-5617452 Retinoic acid activates HOXB1 chromatin IEA Homo sapiens 2644 R-HSA-5617454 https://reactome.org/PathwayBrowser/#/R-HSA-5617454 HOXB1 gene is transcribed IEA Homo sapiens 2644 R-HSA-5617471 https://reactome.org/PathwayBrowser/#/R-HSA-5617471 HOXA1 gene is transcribed IEA Homo sapiens 2644 R-HSA-5617650 https://reactome.org/PathwayBrowser/#/R-HSA-5617650 HOXD3 chromatin is activated IEA Homo sapiens 2644 R-HSA-5617859 https://reactome.org/PathwayBrowser/#/R-HSA-5617859 Retinoic acid activates HOXB4 chromatin IEA Homo sapiens 2644 R-HSA-5617862 https://reactome.org/PathwayBrowser/#/R-HSA-5617862 Retinoic acid activates HOXA4 chromatin IEA Homo sapiens 2644 R-HSA-5617867 https://reactome.org/PathwayBrowser/#/R-HSA-5617867 HOXB4 gene is transcribed IEA Homo sapiens 2644 R-HSA-5617874 https://reactome.org/PathwayBrowser/#/R-HSA-5617874 HOXD4 gene is transcribed IEA Homo sapiens 2644 R-HSA-5617877 https://reactome.org/PathwayBrowser/#/R-HSA-5617877 HOXA4 gene is transcribed IEA Homo sapiens 2644 R-HSA-5617896 https://reactome.org/PathwayBrowser/#/R-HSA-5617896 Retinoic acid activates HOXD4 chromatin IEA Homo sapiens 2644 R-HSA-5622129 https://reactome.org/PathwayBrowser/#/R-HSA-5622129 FABP5 binds atRA TAS Homo sapiens 2644 R-HSA-5622134 https://reactome.org/PathwayBrowser/#/R-HSA-5622134 CRABP1 binds atRA TAS Homo sapiens 2644 R-HSA-5633256 https://reactome.org/PathwayBrowser/#/R-HSA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm TAS Homo sapiens 2644 R-HSA-5634100 https://reactome.org/PathwayBrowser/#/R-HSA-5634100 FABP5 dissociates from RXRA:PPARD:atRA TAS Homo sapiens 2644 R-HSA-5634103 https://reactome.org/PathwayBrowser/#/R-HSA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR TAS Homo sapiens 2644 R-HSA-5634104 https://reactome.org/PathwayBrowser/#/R-HSA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus TAS Homo sapiens 2644 R-HSA-5693644 https://reactome.org/PathwayBrowser/#/R-HSA-5693644 HOXB1 maintains activation of HOXB1 chromatin IEA Homo sapiens 2644 R-HSA-6810139 https://reactome.org/PathwayBrowser/#/R-HSA-6810139 HOXA2 chromatin is activated IEA Homo sapiens 2644 R-HSA-6810159 https://reactome.org/PathwayBrowser/#/R-HSA-6810159 HOXB2 chromatin is activated IEA Homo sapiens 2644 R-HSA-8869568 https://reactome.org/PathwayBrowser/#/R-HSA-8869568 NPM1 binds TFAP2A homodimer TAS Homo sapiens 2644 R-HSA-9617067 https://reactome.org/PathwayBrowser/#/R-HSA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene TAS Homo sapiens 2644 R-HSA-9634433 https://reactome.org/PathwayBrowser/#/R-HSA-9634433 CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid IEA Homo sapiens 2644 R-HSA-9727359 https://reactome.org/PathwayBrowser/#/R-HSA-9727359 Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis TAS Homo sapiens 2644 R-HSA-9761166 https://reactome.org/PathwayBrowser/#/R-HSA-9761166 Expression of LHX1 in intermediate mesoderm IEA Homo sapiens 2644 R-HSA-9761170 https://reactome.org/PathwayBrowser/#/R-HSA-9761170 Expression of PAX2 in intermediate mesoderm IEA Homo sapiens 2644 R-HSA-9761173 https://reactome.org/PathwayBrowser/#/R-HSA-9761173 Expression of PAX8 in intermediate mesoderm IEA Homo sapiens 2644 R-HSA-9761186 https://reactome.org/PathwayBrowser/#/R-HSA-9761186 Expression of OSR1 in intermediate mesoderm IEA Homo sapiens 2644 R-HSA-9830480 https://reactome.org/PathwayBrowser/#/R-HSA-9830480 Expression of RET in the nephric duct IEA Homo sapiens 2644 R-HSA-9839371 https://reactome.org/PathwayBrowser/#/R-HSA-9839371 TGFBR3 transcription TAS Homo sapiens 2644 R-HSA-9860125 https://reactome.org/PathwayBrowser/#/R-HSA-9860125 Binding of ATRA to TGFBR3 gene promoter TAS Homo sapiens 2644 R-HSA-9909325 https://reactome.org/PathwayBrowser/#/R-HSA-9909325 Dorsal foregut endoderm cell produces duodeno-pancreatic endoderm cell TAS Homo sapiens 2644 R-HSA-9911210 https://reactome.org/PathwayBrowser/#/R-HSA-9911210 Definitive endoderm cell produces dorsal foregut endoderm cell TAS Homo sapiens 2644 R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A transfers PALM to CAR IEA Mus musculus 2644 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 2644 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 2644 R-MMU-5246478 https://reactome.org/PathwayBrowser/#/R-MMU-5246478 APOM binds retinoids IEA Mus musculus 2644 R-MMU-5334827 https://reactome.org/PathwayBrowser/#/R-MMU-5334827 SUMO-CRABP2 binds atRA IEA Mus musculus 2644 R-MMU-5334854 https://reactome.org/PathwayBrowser/#/R-MMU-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Mus musculus 2644 R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 2644 R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 2644 R-MMU-5422942 https://reactome.org/PathwayBrowser/#/R-MMU-5422942 RXRA:PPARD binds FABP5:atRA IEA Mus musculus 2644 R-MMU-5617960 https://reactome.org/PathwayBrowser/#/R-MMU-5617960 Retinoic acid activates Hoxb1 chromatin TAS Mus musculus 2644 R-MMU-5617972 https://reactome.org/PathwayBrowser/#/R-MMU-5617972 Hoxb1 gene is transcribed TAS Mus musculus 2644 R-MMU-5617990 https://reactome.org/PathwayBrowser/#/R-MMU-5617990 Retinoic acid activates Hoxa1 chromatin TAS Mus musculus 2644 R-MMU-5617999 https://reactome.org/PathwayBrowser/#/R-MMU-5617999 Hoxa1 gene is transcribed TAS Mus musculus 2644 R-MMU-5619411 https://reactome.org/PathwayBrowser/#/R-MMU-5619411 Retinoic acid activates Hoxb4 chromatin TAS Mus musculus 2644 R-MMU-5619414 https://reactome.org/PathwayBrowser/#/R-MMU-5619414 Hoxa4 gene is transcribed TAS Mus musculus 2644 R-MMU-5619417 https://reactome.org/PathwayBrowser/#/R-MMU-5619417 Hoxb4 gene is transcribed TAS Mus musculus 2644 R-MMU-5619421 https://reactome.org/PathwayBrowser/#/R-MMU-5619421 Hoxd4 gene is transcribed TAS Mus musculus 2644 R-MMU-5619434 https://reactome.org/PathwayBrowser/#/R-MMU-5619434 Retinoic acid activates Hoxa4 chromatin TAS Mus musculus 2644 R-MMU-5619441 https://reactome.org/PathwayBrowser/#/R-MMU-5619441 Retinoic acid activates Hoxd4 chromatin TAS Mus musculus 2644 R-MMU-5622129 https://reactome.org/PathwayBrowser/#/R-MMU-5622129 FABP5 binds atRA IEA Mus musculus 2644 R-MMU-5622134 https://reactome.org/PathwayBrowser/#/R-MMU-5622134 CRABP1 binds atRA IEA Mus musculus 2644 R-MMU-5633256 https://reactome.org/PathwayBrowser/#/R-MMU-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Mus musculus 2644 R-MMU-5634100 https://reactome.org/PathwayBrowser/#/R-MMU-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Mus musculus 2644 R-MMU-5634103 https://reactome.org/PathwayBrowser/#/R-MMU-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Mus musculus 2644 R-MMU-5634104 https://reactome.org/PathwayBrowser/#/R-MMU-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Mus musculus 2644 R-MMU-5693628 https://reactome.org/PathwayBrowser/#/R-MMU-5693628 Hoxb1 maintains activation of Hoxb1 chromatin TAS Mus musculus 2644 R-MMU-8869568 https://reactome.org/PathwayBrowser/#/R-MMU-8869568 NPM1 binds TFAP2A homodimer IEA Mus musculus 2644 R-MMU-9617067 https://reactome.org/PathwayBrowser/#/R-MMU-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Mus musculus 2644 R-MMU-9761177 https://reactome.org/PathwayBrowser/#/R-MMU-9761177 Expression of Pax2 in intermediate mesoderm TAS Mus musculus 2644 R-MMU-9761192 https://reactome.org/PathwayBrowser/#/R-MMU-9761192 Expression of Pax8 in intermediate mesoderm TAS Mus musculus 2644 R-MMU-9766551 https://reactome.org/PathwayBrowser/#/R-MMU-9766551 Expression of Osr1 in intermediate mesoderm TAS Mus musculus 2644 R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A transfers PALM to CAR IEA Rattus norvegicus 2644 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 2644 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 2644 R-RNO-5246478 https://reactome.org/PathwayBrowser/#/R-RNO-5246478 APOM binds retinoids IEA Rattus norvegicus 2644 R-RNO-5334827 https://reactome.org/PathwayBrowser/#/R-RNO-5334827 SUMO-CRABP2 binds atRA IEA Rattus norvegicus 2644 R-RNO-5334854 https://reactome.org/PathwayBrowser/#/R-RNO-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Rattus norvegicus 2644 R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 2644 R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 2644 R-RNO-5422942 https://reactome.org/PathwayBrowser/#/R-RNO-5422942 RXRA:PPARD binds FABP5:atRA IEA Rattus norvegicus 2644 R-RNO-5622129 https://reactome.org/PathwayBrowser/#/R-RNO-5622129 FABP5 binds atRA IEA Rattus norvegicus 2644 R-RNO-5622134 https://reactome.org/PathwayBrowser/#/R-RNO-5622134 CRABP1 binds atRA IEA Rattus norvegicus 2644 R-RNO-5633256 https://reactome.org/PathwayBrowser/#/R-RNO-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Rattus norvegicus 2644 R-RNO-5634100 https://reactome.org/PathwayBrowser/#/R-RNO-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Rattus norvegicus 2644 R-RNO-5634103 https://reactome.org/PathwayBrowser/#/R-RNO-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Rattus norvegicus 2644 R-RNO-5634104 https://reactome.org/PathwayBrowser/#/R-RNO-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Rattus norvegicus 2644 R-RNO-8869568 https://reactome.org/PathwayBrowser/#/R-RNO-8869568 NPM1 binds TFAP2A homodimer IEA Rattus norvegicus 2644 R-RNO-9617067 https://reactome.org/PathwayBrowser/#/R-RNO-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Rattus norvegicus 2644 R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 2644 R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 2644 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A transfers PALM to CAR IEA Sus scrofa 2644 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 2644 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 2644 R-SSC-5246478 https://reactome.org/PathwayBrowser/#/R-SSC-5246478 APOM binds retinoids IEA Sus scrofa 2644 R-SSC-5334827 https://reactome.org/PathwayBrowser/#/R-SSC-5334827 SUMO-CRABP2 binds atRA IEA Sus scrofa 2644 R-SSC-5334854 https://reactome.org/PathwayBrowser/#/R-SSC-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Sus scrofa 2644 R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 2644 R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 2644 R-SSC-5422942 https://reactome.org/PathwayBrowser/#/R-SSC-5422942 RXRA:PPARD binds FABP5:atRA IEA Sus scrofa 2644 R-SSC-5622129 https://reactome.org/PathwayBrowser/#/R-SSC-5622129 FABP5 binds atRA IEA Sus scrofa 2644 R-SSC-5622134 https://reactome.org/PathwayBrowser/#/R-SSC-5622134 CRABP1 binds atRA IEA Sus scrofa 2644 R-SSC-5633256 https://reactome.org/PathwayBrowser/#/R-SSC-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Sus scrofa 2644 R-SSC-5634100 https://reactome.org/PathwayBrowser/#/R-SSC-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Sus scrofa 2644 R-SSC-5634103 https://reactome.org/PathwayBrowser/#/R-SSC-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Sus scrofa 2644 R-SSC-5634104 https://reactome.org/PathwayBrowser/#/R-SSC-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Sus scrofa 2644 R-SSC-8869568 https://reactome.org/PathwayBrowser/#/R-SSC-8869568 NPM1 binds TFAP2A homodimer IEA Sus scrofa 2644 R-SSC-9617067 https://reactome.org/PathwayBrowser/#/R-SSC-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Sus scrofa 2644 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 2644 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 2644 R-XTR-5246478 https://reactome.org/PathwayBrowser/#/R-XTR-5246478 APOM binds retinoids IEA Xenopus tropicalis 2644 R-XTR-5334827 https://reactome.org/PathwayBrowser/#/R-XTR-5334827 SUMO-CRABP2 binds atRA IEA Xenopus tropicalis 2644 R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 2644 R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 2644 R-XTR-5422942 https://reactome.org/PathwayBrowser/#/R-XTR-5422942 RXRA:PPARD binds FABP5:atRA IEA Xenopus tropicalis 2644 R-XTR-5622129 https://reactome.org/PathwayBrowser/#/R-XTR-5622129 FABP5 binds atRA IEA Xenopus tropicalis 2644 R-XTR-5622134 https://reactome.org/PathwayBrowser/#/R-XTR-5622134 CRABP1 binds atRA IEA Xenopus tropicalis 2644 R-XTR-5633256 https://reactome.org/PathwayBrowser/#/R-XTR-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Xenopus tropicalis 2644 R-XTR-5634100 https://reactome.org/PathwayBrowser/#/R-XTR-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Xenopus tropicalis 2644 R-XTR-5634104 https://reactome.org/PathwayBrowser/#/R-XTR-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Xenopus tropicalis 2644 R-XTR-8869568 https://reactome.org/PathwayBrowser/#/R-XTR-8869568 NPM1 binds TFAP2A homodimer IEA Xenopus tropicalis 2645 R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 2645 R-BTA-5246478 https://reactome.org/PathwayBrowser/#/R-BTA-5246478 APOM binds retinoids IEA Bos taurus 2645 R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 2645 R-BTA-9843117 https://reactome.org/PathwayBrowser/#/R-BTA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Bos taurus 2645 R-BTA-9843118 https://reactome.org/PathwayBrowser/#/R-BTA-9843118 RXRA binds ligands IEA Bos taurus 2645 R-BTA-9843120 https://reactome.org/PathwayBrowser/#/R-BTA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Bos taurus 2645 R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 2645 R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 2645 R-CFA-5246478 https://reactome.org/PathwayBrowser/#/R-CFA-5246478 APOM binds retinoids IEA Canis familiaris 2645 R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 2645 R-CFA-9843117 https://reactome.org/PathwayBrowser/#/R-CFA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Canis familiaris 2645 R-CFA-9843118 https://reactome.org/PathwayBrowser/#/R-CFA-9843118 RXRA binds ligands IEA Canis familiaris 2645 R-CFA-9843120 https://reactome.org/PathwayBrowser/#/R-CFA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Canis familiaris 2645 R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 2645 R-DME-9843117 https://reactome.org/PathwayBrowser/#/R-DME-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Drosophila melanogaster 2645 R-DME-9843118 https://reactome.org/PathwayBrowser/#/R-DME-9843118 RXRA binds ligands IEA Drosophila melanogaster 2645 R-DME-9843120 https://reactome.org/PathwayBrowser/#/R-DME-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Drosophila melanogaster 2645 R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 2645 R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 2645 R-DRE-9843118 https://reactome.org/PathwayBrowser/#/R-DRE-9843118 RXRA binds ligands IEA Danio rerio 2645 R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 2645 R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 2645 R-GGA-9843117 https://reactome.org/PathwayBrowser/#/R-GGA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Gallus gallus 2645 R-GGA-9843118 https://reactome.org/PathwayBrowser/#/R-GGA-9843118 RXRA binds ligands IEA Gallus gallus 2645 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus 2645 R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 2645 R-HSA-5246478 https://reactome.org/PathwayBrowser/#/R-HSA-5246478 APOM binds retinoids TAS Homo sapiens 2645 R-HSA-5602050 https://reactome.org/PathwayBrowser/#/R-HSA-5602050 Defective CYP26C1 does not 4-hydroxylate 9cRA TAS Homo sapiens 2645 R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 2645 R-HSA-9843116 https://reactome.org/PathwayBrowser/#/R-HSA-9843116 PPARG2 transcription is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9843117 https://reactome.org/PathwayBrowser/#/R-HSA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer TAS Homo sapiens 2645 R-HSA-9843118 https://reactome.org/PathwayBrowser/#/R-HSA-9843118 RXRA binds ligands TAS Homo sapiens 2645 R-HSA-9843119 https://reactome.org/PathwayBrowser/#/R-HSA-9843119 MLL4-ASCOM,(MLL3-ASCOM) complex is recruited to ligand- and coactivator-bound PPARG:RXRA heterodimer IEA Homo sapiens 2645 R-HSA-9843120 https://reactome.org/PathwayBrowser/#/R-HSA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer TAS Homo sapiens 2645 R-HSA-9843121 https://reactome.org/PathwayBrowser/#/R-HSA-9843121 KMT2D,(KMT2C) complex monomethylates nucleosomes at PPARG:RXRA-bound enhancers IEA Homo sapiens 2645 R-HSA-9843900 https://reactome.org/PathwayBrowser/#/R-HSA-9843900 FABP4 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 2645 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 2645 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 2645 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 2645 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 2645 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 2645 R-HSA-9851530 https://reactome.org/PathwayBrowser/#/R-HSA-9851530 CD36 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9851534 https://reactome.org/PathwayBrowser/#/R-HSA-9851534 CIDEC gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9851539 https://reactome.org/PathwayBrowser/#/R-HSA-9851539 SCD gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9854128 https://reactome.org/PathwayBrowser/#/R-HSA-9854128 ACSS3 gene expression is stimulated by PPARG2:RXRA:MLL4(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9854130 https://reactome.org/PathwayBrowser/#/R-HSA-9854130 THRSP gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9854141 https://reactome.org/PathwayBrowser/#/R-HSA-9854141 GPAM gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9854142 https://reactome.org/PathwayBrowser/#/R-HSA-9854142 ELOVL5 gene expression is stimulated by PPARG2:RXRA:MLL4(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9854146 https://reactome.org/PathwayBrowser/#/R-HSA-9854146 SCD5 gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9856211 https://reactome.org/PathwayBrowser/#/R-HSA-9856211 ADIPOQ gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9856486 https://reactome.org/PathwayBrowser/#/R-HSA-9856486 CEBPA gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859005 https://reactome.org/PathwayBrowser/#/R-HSA-9859005 PEX11A gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859007 https://reactome.org/PathwayBrowser/#/R-HSA-9859007 PLIN1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859082 https://reactome.org/PathwayBrowser/#/R-HSA-9859082 PNPLA2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859084 https://reactome.org/PathwayBrowser/#/R-HSA-9859084 AGPAT2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859119 https://reactome.org/PathwayBrowser/#/R-HSA-9859119 PDK4 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859121 https://reactome.org/PathwayBrowser/#/R-HSA-9859121 ANGPTL4 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859182 https://reactome.org/PathwayBrowser/#/R-HSA-9859182 LPL gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859188 https://reactome.org/PathwayBrowser/#/R-HSA-9859188 ACSL1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859196 https://reactome.org/PathwayBrowser/#/R-HSA-9859196 PLIN2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859206 https://reactome.org/PathwayBrowser/#/R-HSA-9859206 PLIN4 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859223 https://reactome.org/PathwayBrowser/#/R-HSA-9859223 LIPE gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859273 https://reactome.org/PathwayBrowser/#/R-HSA-9859273 MGLL gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859291 https://reactome.org/PathwayBrowser/#/R-HSA-9859291 DGAT2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-HSA-9859334 https://reactome.org/PathwayBrowser/#/R-HSA-9859334 LPIN1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 2645 R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 2645 R-MMU-5246478 https://reactome.org/PathwayBrowser/#/R-MMU-5246478 APOM binds retinoids IEA Mus musculus 2645 R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 2645 R-MMU-9843118 https://reactome.org/PathwayBrowser/#/R-MMU-9843118 RXRA binds ligands IEA Mus musculus 2645 R-MMU-9843904 https://reactome.org/PathwayBrowser/#/R-MMU-9843904 Fabp4 gene transcription is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 2645 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 2645 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 2645 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 2645 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 2645 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 2645 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 2645 R-MMU-9856206 https://reactome.org/PathwayBrowser/#/R-MMU-9856206 Mll4-ASCOM,(Mll3-ASCOM) complex is recruited to activated Pparg:Rxra complex at target adipogenic gene loci TAS Mus musculus 2645 R-MMU-9856214 https://reactome.org/PathwayBrowser/#/R-MMU-9856214 Adipoq gene expression is stimulated by Pparg and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9856368 https://reactome.org/PathwayBrowser/#/R-MMU-9856368 Kmt2d,(Kmt2c) monomethylates nucleosomes at Pparg:Rxra-bound enhancers TAS Mus musculus 2645 R-MMU-9906987 https://reactome.org/PathwayBrowser/#/R-MMU-9906987 Acsl1 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9906989 https://reactome.org/PathwayBrowser/#/R-MMU-9906989 Acss3 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9906994 https://reactome.org/PathwayBrowser/#/R-MMU-9906994 Agpat2 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907162 https://reactome.org/PathwayBrowser/#/R-MMU-9907162 Angptl4 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907166 https://reactome.org/PathwayBrowser/#/R-MMU-9907166 Cd36 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907178 https://reactome.org/PathwayBrowser/#/R-MMU-9907178 Cidec gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907190 https://reactome.org/PathwayBrowser/#/R-MMU-9907190 Dgat2 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907194 https://reactome.org/PathwayBrowser/#/R-MMU-9907194 Elovl5 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907201 https://reactome.org/PathwayBrowser/#/R-MMU-9907201 Gpam gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907236 https://reactome.org/PathwayBrowser/#/R-MMU-9907236 Pdk4 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907261 https://reactome.org/PathwayBrowser/#/R-MMU-9907261 Pex11a gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907267 https://reactome.org/PathwayBrowser/#/R-MMU-9907267 Plin1 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907270 https://reactome.org/PathwayBrowser/#/R-MMU-9907270 Plin2 gene expression is positively regulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907291 https://reactome.org/PathwayBrowser/#/R-MMU-9907291 Scd1 gene expression is stimulated by p-Y78,Y102-Pparg2:Rxra and Mll4,(Mll3) TAS Mus musculus 2645 R-MMU-9907296 https://reactome.org/PathwayBrowser/#/R-MMU-9907296 Scd4 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-MMU-9907303 https://reactome.org/PathwayBrowser/#/R-MMU-9907303 Thrsp gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 2645 R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 2645 R-RNO-5246478 https://reactome.org/PathwayBrowser/#/R-RNO-5246478 APOM binds retinoids IEA Rattus norvegicus 2645 R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 2645 R-RNO-9843117 https://reactome.org/PathwayBrowser/#/R-RNO-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Rattus norvegicus 2645 R-RNO-9843118 https://reactome.org/PathwayBrowser/#/R-RNO-9843118 RXRA binds ligands IEA Rattus norvegicus 2645 R-RNO-9843120 https://reactome.org/PathwayBrowser/#/R-RNO-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Rattus norvegicus 2645 R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 2645 R-SSC-5246478 https://reactome.org/PathwayBrowser/#/R-SSC-5246478 APOM binds retinoids IEA Sus scrofa 2645 R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 2645 R-SSC-9843117 https://reactome.org/PathwayBrowser/#/R-SSC-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Sus scrofa 2645 R-SSC-9843118 https://reactome.org/PathwayBrowser/#/R-SSC-9843118 RXRA binds ligands IEA Sus scrofa 2645 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa 2645 R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 2645 R-XTR-5246478 https://reactome.org/PathwayBrowser/#/R-XTR-5246478 APOM binds retinoids IEA Xenopus tropicalis 2645 R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 2645 R-XTR-9843118 https://reactome.org/PathwayBrowser/#/R-XTR-9843118 RXRA binds ligands IEA Xenopus tropicalis 2667 R-BTA-9734475 https://reactome.org/PathwayBrowser/#/R-BTA-9734475 PPARA binds fibrates IEA Bos taurus 2667 R-CFA-9734475 https://reactome.org/PathwayBrowser/#/R-CFA-9734475 PPARA binds fibrates IEA Canis familiaris 2667 R-DME-9734475 https://reactome.org/PathwayBrowser/#/R-DME-9734475 PPARA binds fibrates IEA Drosophila melanogaster 2667 R-DRE-9734475 https://reactome.org/PathwayBrowser/#/R-DRE-9734475 PPARA binds fibrates IEA Danio rerio 2667 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus 2667 R-HSA-9734475 https://reactome.org/PathwayBrowser/#/R-HSA-9734475 PPARA binds fibrates TAS Homo sapiens 2667 R-MMU-9734475 https://reactome.org/PathwayBrowser/#/R-MMU-9734475 PPARA binds fibrates IEA Mus musculus 2667 R-RNO-9734475 https://reactome.org/PathwayBrowser/#/R-RNO-9734475 PPARA binds fibrates IEA Rattus norvegicus 2667 R-SSC-9734475 https://reactome.org/PathwayBrowser/#/R-SSC-9734475 PPARA binds fibrates IEA Sus scrofa 2667 R-XTR-9734475 https://reactome.org/PathwayBrowser/#/R-XTR-9734475 PPARA binds fibrates IEA Xenopus tropicalis 2668 R-BTA-9734475 https://reactome.org/PathwayBrowser/#/R-BTA-9734475 PPARA binds fibrates IEA Bos taurus 2668 R-CFA-9734475 https://reactome.org/PathwayBrowser/#/R-CFA-9734475 PPARA binds fibrates IEA Canis familiaris 2668 R-DME-9734475 https://reactome.org/PathwayBrowser/#/R-DME-9734475 PPARA binds fibrates IEA Drosophila melanogaster 2668 R-DRE-9734475 https://reactome.org/PathwayBrowser/#/R-DRE-9734475 PPARA binds fibrates IEA Danio rerio 2668 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus 2668 R-HSA-9734475 https://reactome.org/PathwayBrowser/#/R-HSA-9734475 PPARA binds fibrates TAS Homo sapiens 2668 R-MMU-9734475 https://reactome.org/PathwayBrowser/#/R-MMU-9734475 PPARA binds fibrates IEA Mus musculus 2668 R-RNO-9734475 https://reactome.org/PathwayBrowser/#/R-RNO-9734475 PPARA binds fibrates IEA Rattus norvegicus 2668 R-SSC-9734475 https://reactome.org/PathwayBrowser/#/R-SSC-9734475 PPARA binds fibrates IEA Sus scrofa 2668 R-XTR-9734475 https://reactome.org/PathwayBrowser/#/R-XTR-9734475 PPARA binds fibrates IEA Xenopus tropicalis 2677 R-BTA-8937419 https://reactome.org/PathwayBrowser/#/R-BTA-8937419 CBR3 reduces DOX to DOXOL IEA Bos taurus 2677 R-CFA-8937419 https://reactome.org/PathwayBrowser/#/R-CFA-8937419 CBR3 reduces DOX to DOXOL IEA Canis familiaris 2677 R-DRE-8937419 https://reactome.org/PathwayBrowser/#/R-DRE-8937419 CBR3 reduces DOX to DOXOL IEA Danio rerio 2677 R-GGA-8937419 https://reactome.org/PathwayBrowser/#/R-GGA-8937419 CBR3 reduces DOX to DOXOL IEA Gallus gallus 2677 R-HSA-8937419 https://reactome.org/PathwayBrowser/#/R-HSA-8937419 CBR3 reduces DOX to DOXOL TAS Homo sapiens 2677 R-MMU-8937419 https://reactome.org/PathwayBrowser/#/R-MMU-8937419 CBR3 reduces DOX to DOXOL IEA Mus musculus 2677 R-RNO-8937419 https://reactome.org/PathwayBrowser/#/R-RNO-8937419 CBR3 reduces DOX to DOXOL IEA Rattus norvegicus 2677 R-SSC-8937419 https://reactome.org/PathwayBrowser/#/R-SSC-8937419 CBR3 reduces DOX to DOXOL IEA Sus scrofa 2677 R-XTR-8937419 https://reactome.org/PathwayBrowser/#/R-XTR-8937419 CBR3 reduces DOX to DOXOL IEA Xenopus tropicalis 2693 R-BTA-9732629 https://reactome.org/PathwayBrowser/#/R-BTA-9732629 PPARG binds PPARG agonists IEA Bos taurus 2693 R-CEL-9732629 https://reactome.org/PathwayBrowser/#/R-CEL-9732629 PPARG binds PPARG agonists IEA Caenorhabditis elegans 2693 R-CFA-9732629 https://reactome.org/PathwayBrowser/#/R-CFA-9732629 PPARG binds PPARG agonists IEA Canis familiaris 2693 R-DME-9732629 https://reactome.org/PathwayBrowser/#/R-DME-9732629 PPARG binds PPARG agonists IEA Drosophila melanogaster 2693 R-GGA-9732629 https://reactome.org/PathwayBrowser/#/R-GGA-9732629 PPARG binds PPARG agonists IEA Gallus gallus 2693 R-HSA-9732629 https://reactome.org/PathwayBrowser/#/R-HSA-9732629 PPARG binds PPARG agonists TAS Homo sapiens 2693 R-MMU-9732629 https://reactome.org/PathwayBrowser/#/R-MMU-9732629 PPARG binds PPARG agonists IEA Mus musculus 2693 R-RNO-9732629 https://reactome.org/PathwayBrowser/#/R-RNO-9732629 PPARG binds PPARG agonists IEA Rattus norvegicus 2693 R-SSC-9732629 https://reactome.org/PathwayBrowser/#/R-SSC-9732629 PPARG binds PPARG agonists IEA Sus scrofa 2694 R-BTA-9732629 https://reactome.org/PathwayBrowser/#/R-BTA-9732629 PPARG binds PPARG agonists IEA Bos taurus 2694 R-CEL-9732629 https://reactome.org/PathwayBrowser/#/R-CEL-9732629 PPARG binds PPARG agonists IEA Caenorhabditis elegans 2694 R-CFA-9732629 https://reactome.org/PathwayBrowser/#/R-CFA-9732629 PPARG binds PPARG agonists IEA Canis familiaris 2694 R-DME-9732629 https://reactome.org/PathwayBrowser/#/R-DME-9732629 PPARG binds PPARG agonists IEA Drosophila melanogaster 2694 R-GGA-9732629 https://reactome.org/PathwayBrowser/#/R-GGA-9732629 PPARG binds PPARG agonists IEA Gallus gallus 2694 R-HSA-9732629 https://reactome.org/PathwayBrowser/#/R-HSA-9732629 PPARG binds PPARG agonists TAS Homo sapiens 2694 R-MMU-9732629 https://reactome.org/PathwayBrowser/#/R-MMU-9732629 PPARG binds PPARG agonists IEA Mus musculus 2694 R-RNO-9732629 https://reactome.org/PathwayBrowser/#/R-RNO-9732629 PPARG binds PPARG agonists IEA Rattus norvegicus 2694 R-SSC-9732629 https://reactome.org/PathwayBrowser/#/R-SSC-9732629 PPARG binds PPARG agonists IEA Sus scrofa 2713 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 2713 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 2713 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 2713 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 2713 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 2713 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 2713 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 2713 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 2713 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 2713 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 2713 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 2713 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 2713 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 2713 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 2713 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 2713 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 2713 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 2713 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 2714 R-BTA-9649963 https://reactome.org/PathwayBrowser/#/R-BTA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Bos taurus 2714 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 2714 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 2714 R-CEL-9649963 https://reactome.org/PathwayBrowser/#/R-CEL-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Caenorhabditis elegans 2714 R-CFA-9649963 https://reactome.org/PathwayBrowser/#/R-CFA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Canis familiaris 2714 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 2714 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 2714 R-DME-9649963 https://reactome.org/PathwayBrowser/#/R-DME-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Drosophila melanogaster 2714 R-DRE-9649963 https://reactome.org/PathwayBrowser/#/R-DRE-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Danio rerio 2714 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 2714 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 2714 R-GGA-9649963 https://reactome.org/PathwayBrowser/#/R-GGA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Gallus gallus 2714 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 2714 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 2714 R-HSA-9649963 https://reactome.org/PathwayBrowser/#/R-HSA-9649963 ASIC3 channel blockers bind ASIC3 trimer TAS Homo sapiens 2714 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 2714 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 2714 R-MMU-9649963 https://reactome.org/PathwayBrowser/#/R-MMU-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Mus musculus 2714 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 2714 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 2714 R-RNO-9649963 https://reactome.org/PathwayBrowser/#/R-RNO-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Rattus norvegicus 2714 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 2714 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 2714 R-SSC-9649963 https://reactome.org/PathwayBrowser/#/R-SSC-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Sus scrofa 2714 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 2714 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 2714 R-XTR-9649963 https://reactome.org/PathwayBrowser/#/R-XTR-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Xenopus tropicalis 2714 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 2714 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 2718 R-BTA-1454928 https://reactome.org/PathwayBrowser/#/R-BTA-1454928 ABCG4 may mediate cholesterol efflux IEA Bos taurus 2718 R-BTA-171059 https://reactome.org/PathwayBrowser/#/R-BTA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Bos taurus 2718 R-BTA-171106 https://reactome.org/PathwayBrowser/#/R-BTA-171106 LDLR:LDL complex => LDLR + LDL IEA Bos taurus 2718 R-BTA-171122 https://reactome.org/PathwayBrowser/#/R-BTA-171122 LDL + LDLR => LDL:LDLR complex IEA Bos taurus 2718 R-BTA-171141 https://reactome.org/PathwayBrowser/#/R-BTA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Bos taurus 2718 R-BTA-174587 https://reactome.org/PathwayBrowser/#/R-BTA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Bos taurus 2718 R-BTA-174657 https://reactome.org/PathwayBrowser/#/R-BTA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Bos taurus 2718 R-BTA-174660 https://reactome.org/PathwayBrowser/#/R-BTA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Bos taurus 2718 R-BTA-174690 https://reactome.org/PathwayBrowser/#/R-BTA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Bos taurus 2718 R-BTA-174706 https://reactome.org/PathwayBrowser/#/R-BTA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Bos taurus 2718 R-BTA-174739 https://reactome.org/PathwayBrowser/#/R-BTA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Bos taurus 2718 R-BTA-174741 https://reactome.org/PathwayBrowser/#/R-BTA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Bos taurus 2718 R-BTA-174757 https://reactome.org/PathwayBrowser/#/R-BTA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Bos taurus 2718 R-BTA-176609 https://reactome.org/PathwayBrowser/#/R-BTA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Bos taurus 2718 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 2718 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 2718 R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 2718 R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 2718 R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 2718 R-BTA-196126 https://reactome.org/PathwayBrowser/#/R-BTA-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space IEA Bos taurus 2718 R-BTA-196417 https://reactome.org/PathwayBrowser/#/R-BTA-196417 Reduction of desmosterol to cholesterol IEA Bos taurus 2718 R-BTA-203130 https://reactome.org/PathwayBrowser/#/R-BTA-203130 OLR1 binds to oxidized LDL IEA Bos taurus 2718 R-BTA-216723 https://reactome.org/PathwayBrowser/#/R-BTA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Bos taurus 2718 R-BTA-216756 https://reactome.org/PathwayBrowser/#/R-BTA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Bos taurus 2718 R-BTA-2187261 https://reactome.org/PathwayBrowser/#/R-BTA-2187261 COLEC12 (SCARA4) binds ligands IEA Bos taurus 2718 R-BTA-2187332 https://reactome.org/PathwayBrowser/#/R-BTA-2187332 Cytosolic CMs translocate to extracellular region IEA Bos taurus 2718 R-BTA-2197646 https://reactome.org/PathwayBrowser/#/R-BTA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Bos taurus 2718 R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 2718 R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 2718 R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 2718 R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 2718 R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 2718 R-BTA-2395764 https://reactome.org/PathwayBrowser/#/R-BTA-2395764 atREs binds to nascent CM IEA Bos taurus 2718 R-BTA-2395768 https://reactome.org/PathwayBrowser/#/R-BTA-2395768 LPL hydrolyses TGs from mature CMs IEA Bos taurus 2718 R-BTA-2395784 https://reactome.org/PathwayBrowser/#/R-BTA-2395784 Nascent CMs transform into mature CMs IEA Bos taurus 2718 R-BTA-2404131 https://reactome.org/PathwayBrowser/#/R-BTA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Bos taurus 2718 R-BTA-2423785 https://reactome.org/PathwayBrowser/#/R-BTA-2423785 CR:atREs binds apoE and HSPG IEA Bos taurus 2718 R-BTA-2512800 https://reactome.org/PathwayBrowser/#/R-BTA-2512800 SCARB1:ligand is endocytosed IEA Bos taurus 2718 R-BTA-264678 https://reactome.org/PathwayBrowser/#/R-BTA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Bos taurus 2718 R-BTA-264689 https://reactome.org/PathwayBrowser/#/R-BTA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Bos taurus 2718 R-BTA-264695 https://reactome.org/PathwayBrowser/#/R-BTA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Bos taurus 2718 R-BTA-265783 https://reactome.org/PathwayBrowser/#/R-BTA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Bos taurus 2718 R-BTA-266082 https://reactome.org/PathwayBrowser/#/R-BTA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Bos taurus 2718 R-BTA-266089 https://reactome.org/PathwayBrowser/#/R-BTA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Bos taurus 2718 R-BTA-266299 https://reactome.org/PathwayBrowser/#/R-BTA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Bos taurus 2718 R-BTA-266303 https://reactome.org/PathwayBrowser/#/R-BTA-266303 Spherical HDL binds C and E apolipoproteins IEA Bos taurus 2718 R-BTA-266310 https://reactome.org/PathwayBrowser/#/R-BTA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Bos taurus 2718 R-BTA-266315 https://reactome.org/PathwayBrowser/#/R-BTA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Bos taurus 2718 R-BTA-2981040 https://reactome.org/PathwayBrowser/#/R-BTA-2981040 COLEC12:ligand is endocytosed IEA Bos taurus 2718 R-BTA-349637 https://reactome.org/PathwayBrowser/#/R-BTA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Bos taurus 2718 R-BTA-349638 https://reactome.org/PathwayBrowser/#/R-BTA-349638 Disassembly of SR-BI-bound spherical HDL IEA Bos taurus 2718 R-BTA-349657 https://reactome.org/PathwayBrowser/#/R-BTA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Bos taurus 2718 R-BTA-432121 https://reactome.org/PathwayBrowser/#/R-BTA-432121 LDL binds to LRP8 IEA Bos taurus 2718 R-BTA-432129 https://reactome.org/PathwayBrowser/#/R-BTA-432129 FGR binds and phosphorylates LRP8 IEA Bos taurus 2718 R-BTA-435244 https://reactome.org/PathwayBrowser/#/R-BTA-435244 PECAM1 is phosphorylated IEA Bos taurus 2718 R-BTA-5250531 https://reactome.org/PathwayBrowser/#/R-BTA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Bos taurus 2718 R-BTA-5358340 https://reactome.org/PathwayBrowser/#/R-BTA-5358340 Autoproteolytic cleavage of Hh precursors IEA Bos taurus 2718 R-BTA-6807055 https://reactome.org/PathwayBrowser/#/R-BTA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Bos taurus 2718 R-BTA-6810937 https://reactome.org/PathwayBrowser/#/R-BTA-6810937 Lamellar bodies bind the early cornified envelope IEA Bos taurus 2718 R-BTA-6813720 https://reactome.org/PathwayBrowser/#/R-BTA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Bos taurus 2718 R-BTA-6814387 https://reactome.org/PathwayBrowser/#/R-BTA-6814387 CASP14 cleaves filaggrin IEA Bos taurus 2718 R-BTA-6814734 https://reactome.org/PathwayBrowser/#/R-BTA-6814734 CDSN binds the cornified envelope IEA Bos taurus 2718 R-BTA-6814764 https://reactome.org/PathwayBrowser/#/R-BTA-6814764 Plasma membrane resorption IEA Bos taurus 2718 R-BTA-8848053 https://reactome.org/PathwayBrowser/#/R-BTA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Bos taurus 2718 R-BTA-8858252 https://reactome.org/PathwayBrowser/#/R-BTA-8858252 HDLBP binds HDL IEA Bos taurus 2718 R-BTA-8863471 https://reactome.org/PathwayBrowser/#/R-BTA-8863471 LDLR is bound by DAB2 and ARH IEA Bos taurus 2718 R-BTA-8865667 https://reactome.org/PathwayBrowser/#/R-BTA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Bos taurus 2718 R-BTA-8866304 https://reactome.org/PathwayBrowser/#/R-BTA-8866304 pre-VLDL binds lipids to form VLDL IEA Bos taurus 2718 R-BTA-8866327 https://reactome.org/PathwayBrowser/#/R-BTA-8866327 VLDL translocates from SER lumen to extracellular region IEA Bos taurus 2718 R-BTA-8867754 https://reactome.org/PathwayBrowser/#/R-BTA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Bos taurus 2718 R-BTA-8867756 https://reactome.org/PathwayBrowser/#/R-BTA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Bos taurus 2718 R-BTA-8868071 https://reactome.org/PathwayBrowser/#/R-BTA-8868071 Clathrin recruits PIK3C2A IEA Bos taurus 2718 R-BTA-8868072 https://reactome.org/PathwayBrowser/#/R-BTA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Bos taurus 2718 R-BTA-8868230 https://reactome.org/PathwayBrowser/#/R-BTA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Bos taurus 2718 R-BTA-8868236 https://reactome.org/PathwayBrowser/#/R-BTA-8868236 BAR domain proteins recruit dynamin IEA Bos taurus 2718 R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 2718 R-BTA-8868651 https://reactome.org/PathwayBrowser/#/R-BTA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Bos taurus 2718 R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 2718 R-BTA-8868659 https://reactome.org/PathwayBrowser/#/R-BTA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Bos taurus 2718 R-BTA-8868660 https://reactome.org/PathwayBrowser/#/R-BTA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Bos taurus 2718 R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 2718 R-BTA-8869667 https://reactome.org/PathwayBrowser/#/R-BTA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Bos taurus 2718 R-BTA-8871193 https://reactome.org/PathwayBrowser/#/R-BTA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Bos taurus 2718 R-BTA-8871194 https://reactome.org/PathwayBrowser/#/R-BTA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Bos taurus 2718 R-BTA-8876366 https://reactome.org/PathwayBrowser/#/R-BTA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Bos taurus 2718 R-BTA-8876472 https://reactome.org/PathwayBrowser/#/R-BTA-8876472 NPC2 binds CHOL IEA Bos taurus 2718 R-BTA-8876484 https://reactome.org/PathwayBrowser/#/R-BTA-8876484 NPC2 transfers CHOL to NPC1 IEA Bos taurus 2718 R-BTA-8876485 https://reactome.org/PathwayBrowser/#/R-BTA-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Bos taurus 2718 R-BTA-8876696 https://reactome.org/PathwayBrowser/#/R-BTA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Bos taurus 2718 R-BTA-8937442 https://reactome.org/PathwayBrowser/#/R-BTA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Bos taurus 2718 R-BTA-8948034 https://reactome.org/PathwayBrowser/#/R-BTA-8948034 FGR binds LDL:LRP8 IEA Bos taurus 2718 R-BTA-9707586 https://reactome.org/PathwayBrowser/#/R-BTA-9707586 FeHM oxidises LDL,HDL IEA Bos taurus 2718 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 2718 R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 2718 R-CEL-196417 https://reactome.org/PathwayBrowser/#/R-CEL-196417 Reduction of desmosterol to cholesterol IEA Caenorhabditis elegans 2718 R-CEL-264695 https://reactome.org/PathwayBrowser/#/R-CEL-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Caenorhabditis elegans 2718 R-CEL-265783 https://reactome.org/PathwayBrowser/#/R-CEL-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Caenorhabditis elegans 2718 R-CEL-5250531 https://reactome.org/PathwayBrowser/#/R-CEL-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Caenorhabditis elegans 2718 R-CEL-6807055 https://reactome.org/PathwayBrowser/#/R-CEL-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Caenorhabditis elegans 2718 R-CEL-6813720 https://reactome.org/PathwayBrowser/#/R-CEL-6813720 NCEH1 hydrolyzes cholesterol esters IEA Caenorhabditis elegans 2718 R-CEL-8876472 https://reactome.org/PathwayBrowser/#/R-CEL-8876472 NPC2 binds CHOL IEA Caenorhabditis elegans 2718 R-CEL-8876484 https://reactome.org/PathwayBrowser/#/R-CEL-8876484 NPC2 transfers CHOL to NPC1 IEA Caenorhabditis elegans 2718 R-CEL-8876485 https://reactome.org/PathwayBrowser/#/R-CEL-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Caenorhabditis elegans 2718 R-CEL-8876696 https://reactome.org/PathwayBrowser/#/R-CEL-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Caenorhabditis elegans 2718 R-CEL-8937442 https://reactome.org/PathwayBrowser/#/R-CEL-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Caenorhabditis elegans 2718 R-CEL-8951850 https://reactome.org/PathwayBrowser/#/R-CEL-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Caenorhabditis elegans 2718 R-CFA-1454928 https://reactome.org/PathwayBrowser/#/R-CFA-1454928 ABCG4 may mediate cholesterol efflux IEA Canis familiaris 2718 R-CFA-171059 https://reactome.org/PathwayBrowser/#/R-CFA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Canis familiaris 2718 R-CFA-171106 https://reactome.org/PathwayBrowser/#/R-CFA-171106 LDLR:LDL complex => LDLR + LDL IEA Canis familiaris 2718 R-CFA-171122 https://reactome.org/PathwayBrowser/#/R-CFA-171122 LDL + LDLR => LDL:LDLR complex IEA Canis familiaris 2718 R-CFA-171141 https://reactome.org/PathwayBrowser/#/R-CFA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Canis familiaris 2718 R-CFA-174587 https://reactome.org/PathwayBrowser/#/R-CFA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Canis familiaris 2718 R-CFA-174657 https://reactome.org/PathwayBrowser/#/R-CFA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Canis familiaris 2718 R-CFA-174660 https://reactome.org/PathwayBrowser/#/R-CFA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Canis familiaris 2718 R-CFA-174690 https://reactome.org/PathwayBrowser/#/R-CFA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Canis familiaris 2718 R-CFA-174706 https://reactome.org/PathwayBrowser/#/R-CFA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Canis familiaris 2718 R-CFA-174739 https://reactome.org/PathwayBrowser/#/R-CFA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Canis familiaris 2718 R-CFA-174741 https://reactome.org/PathwayBrowser/#/R-CFA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Canis familiaris 2718 R-CFA-174757 https://reactome.org/PathwayBrowser/#/R-CFA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Canis familiaris 2718 R-CFA-176609 https://reactome.org/PathwayBrowser/#/R-CFA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Canis familiaris 2718 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 2718 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 2718 R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 2718 R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 2718 R-CFA-196126 https://reactome.org/PathwayBrowser/#/R-CFA-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space IEA Canis familiaris 2718 R-CFA-196417 https://reactome.org/PathwayBrowser/#/R-CFA-196417 Reduction of desmosterol to cholesterol IEA Canis familiaris 2718 R-CFA-203130 https://reactome.org/PathwayBrowser/#/R-CFA-203130 OLR1 binds to oxidized LDL IEA Canis familiaris 2718 R-CFA-216723 https://reactome.org/PathwayBrowser/#/R-CFA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Canis familiaris 2718 R-CFA-216756 https://reactome.org/PathwayBrowser/#/R-CFA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Canis familiaris 2718 R-CFA-2187332 https://reactome.org/PathwayBrowser/#/R-CFA-2187332 Cytosolic CMs translocate to extracellular region IEA Canis familiaris 2718 R-CFA-2197646 https://reactome.org/PathwayBrowser/#/R-CFA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Canis familiaris 2718 R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 2718 R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 2718 R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 2718 R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 2718 R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 2718 R-CFA-2395764 https://reactome.org/PathwayBrowser/#/R-CFA-2395764 atREs binds to nascent CM IEA Canis familiaris 2718 R-CFA-2395768 https://reactome.org/PathwayBrowser/#/R-CFA-2395768 LPL hydrolyses TGs from mature CMs IEA Canis familiaris 2718 R-CFA-2395784 https://reactome.org/PathwayBrowser/#/R-CFA-2395784 Nascent CMs transform into mature CMs IEA Canis familiaris 2718 R-CFA-2404131 https://reactome.org/PathwayBrowser/#/R-CFA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Canis familiaris 2718 R-CFA-2423785 https://reactome.org/PathwayBrowser/#/R-CFA-2423785 CR:atREs binds apoE and HSPG IEA Canis familiaris 2718 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 2718 R-CFA-2512800 https://reactome.org/PathwayBrowser/#/R-CFA-2512800 SCARB1:ligand is endocytosed IEA Canis familiaris 2718 R-CFA-265529 https://reactome.org/PathwayBrowser/#/R-CFA-265529 NPC1L1-mediated cholesterol uptake TAS Canis familiaris 2718 R-CFA-265783 https://reactome.org/PathwayBrowser/#/R-CFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Canis familiaris 2718 R-CFA-266082 https://reactome.org/PathwayBrowser/#/R-CFA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Canis familiaris 2718 R-CFA-266089 https://reactome.org/PathwayBrowser/#/R-CFA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Canis familiaris 2718 R-CFA-266299 https://reactome.org/PathwayBrowser/#/R-CFA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Canis familiaris 2718 R-CFA-266303 https://reactome.org/PathwayBrowser/#/R-CFA-266303 Spherical HDL binds C and E apolipoproteins IEA Canis familiaris 2718 R-CFA-349637 https://reactome.org/PathwayBrowser/#/R-CFA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Canis familiaris 2718 R-CFA-349638 https://reactome.org/PathwayBrowser/#/R-CFA-349638 Disassembly of SR-BI-bound spherical HDL IEA Canis familiaris 2718 R-CFA-349657 https://reactome.org/PathwayBrowser/#/R-CFA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Canis familiaris 2718 R-CFA-432121 https://reactome.org/PathwayBrowser/#/R-CFA-432121 LDL binds to LRP8 IEA Canis familiaris 2718 R-CFA-432129 https://reactome.org/PathwayBrowser/#/R-CFA-432129 FGR binds and phosphorylates LRP8 IEA Canis familiaris 2718 R-CFA-435244 https://reactome.org/PathwayBrowser/#/R-CFA-435244 PECAM1 is phosphorylated IEA Canis familiaris 2718 R-CFA-5250531 https://reactome.org/PathwayBrowser/#/R-CFA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Canis familiaris 2718 R-CFA-5358340 https://reactome.org/PathwayBrowser/#/R-CFA-5358340 Autoproteolytic cleavage of Hh precursors IEA Canis familiaris 2718 R-CFA-6807055 https://reactome.org/PathwayBrowser/#/R-CFA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Canis familiaris 2718 R-CFA-6810937 https://reactome.org/PathwayBrowser/#/R-CFA-6810937 Lamellar bodies bind the early cornified envelope IEA Canis familiaris 2718 R-CFA-6813720 https://reactome.org/PathwayBrowser/#/R-CFA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Canis familiaris 2718 R-CFA-6814387 https://reactome.org/PathwayBrowser/#/R-CFA-6814387 CASP14 cleaves filaggrin IEA Canis familiaris 2718 R-CFA-6814734 https://reactome.org/PathwayBrowser/#/R-CFA-6814734 CDSN binds the cornified envelope IEA Canis familiaris 2718 R-CFA-6814764 https://reactome.org/PathwayBrowser/#/R-CFA-6814764 Plasma membrane resorption IEA Canis familiaris 2718 R-CFA-8848053 https://reactome.org/PathwayBrowser/#/R-CFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Canis familiaris 2718 R-CFA-8854408 https://reactome.org/PathwayBrowser/#/R-CFA-8854408 APOBR dimer binds VLDLs IEA Canis familiaris 2718 R-CFA-8854462 https://reactome.org/PathwayBrowser/#/R-CFA-8854462 VLDLR binds VLDL IEA Canis familiaris 2718 R-CFA-8858252 https://reactome.org/PathwayBrowser/#/R-CFA-8858252 HDLBP binds HDL IEA Canis familiaris 2718 R-CFA-8863471 https://reactome.org/PathwayBrowser/#/R-CFA-8863471 LDLR is bound by DAB2 and ARH IEA Canis familiaris 2718 R-CFA-8865667 https://reactome.org/PathwayBrowser/#/R-CFA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Canis familiaris 2718 R-CFA-8866304 https://reactome.org/PathwayBrowser/#/R-CFA-8866304 pre-VLDL binds lipids to form VLDL IEA Canis familiaris 2718 R-CFA-8866321 https://reactome.org/PathwayBrowser/#/R-CFA-8866321 VLDL binds APOC1 and APOC4 IEA Canis familiaris 2718 R-CFA-8866327 https://reactome.org/PathwayBrowser/#/R-CFA-8866327 VLDL translocates from SER lumen to extracellular region IEA Canis familiaris 2718 R-CFA-8867754 https://reactome.org/PathwayBrowser/#/R-CFA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Canis familiaris 2718 R-CFA-8867756 https://reactome.org/PathwayBrowser/#/R-CFA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Canis familiaris 2718 R-CFA-8868071 https://reactome.org/PathwayBrowser/#/R-CFA-8868071 Clathrin recruits PIK3C2A IEA Canis familiaris 2718 R-CFA-8868072 https://reactome.org/PathwayBrowser/#/R-CFA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Canis familiaris 2718 R-CFA-8868230 https://reactome.org/PathwayBrowser/#/R-CFA-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Canis familiaris 2718 R-CFA-8868236 https://reactome.org/PathwayBrowser/#/R-CFA-8868236 BAR domain proteins recruit dynamin IEA Canis familiaris 2718 R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 2718 R-CFA-8868651 https://reactome.org/PathwayBrowser/#/R-CFA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Canis familiaris 2718 R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 2718 R-CFA-8868659 https://reactome.org/PathwayBrowser/#/R-CFA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Canis familiaris 2718 R-CFA-8868660 https://reactome.org/PathwayBrowser/#/R-CFA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Canis familiaris 2718 R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 2718 R-CFA-8871193 https://reactome.org/PathwayBrowser/#/R-CFA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Canis familiaris 2718 R-CFA-8871194 https://reactome.org/PathwayBrowser/#/R-CFA-8871194 RAB5 and GAPVD1 bind AP-2 IEA Canis familiaris 2718 R-CFA-8876366 https://reactome.org/PathwayBrowser/#/R-CFA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Canis familiaris 2718 R-CFA-8876472 https://reactome.org/PathwayBrowser/#/R-CFA-8876472 NPC2 binds CHOL IEA Canis familiaris 2718 R-CFA-8876484 https://reactome.org/PathwayBrowser/#/R-CFA-8876484 NPC2 transfers CHOL to NPC1 IEA Canis familiaris 2718 R-CFA-8876485 https://reactome.org/PathwayBrowser/#/R-CFA-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Canis familiaris 2718 R-CFA-8876696 https://reactome.org/PathwayBrowser/#/R-CFA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Canis familiaris 2718 R-CFA-8948034 https://reactome.org/PathwayBrowser/#/R-CFA-8948034 FGR binds LDL:LRP8 IEA Canis familiaris 2718 R-CFA-8951850 https://reactome.org/PathwayBrowser/#/R-CFA-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Canis familiaris 2718 R-CFA-9707586 https://reactome.org/PathwayBrowser/#/R-CFA-9707586 FeHM oxidises LDL,HDL IEA Canis familiaris 2718 R-DDI-1369028 https://reactome.org/PathwayBrowser/#/R-DDI-1369028 ABCAs mediate lipid efflux IEA Dictyostelium discoideum 2718 R-DDI-1369052 https://reactome.org/PathwayBrowser/#/R-DDI-1369052 ABCAs mediate lipid influx IEA Dictyostelium discoideum 2718 R-DDI-1454928 https://reactome.org/PathwayBrowser/#/R-DDI-1454928 ABCG4 may mediate cholesterol efflux IEA Dictyostelium discoideum 2718 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 2718 R-DDI-265783 https://reactome.org/PathwayBrowser/#/R-DDI-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Dictyostelium discoideum 2718 R-DDI-266082 https://reactome.org/PathwayBrowser/#/R-DDI-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Dictyostelium discoideum 2718 R-DDI-5250531 https://reactome.org/PathwayBrowser/#/R-DDI-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Dictyostelium discoideum 2718 R-DDI-6813720 https://reactome.org/PathwayBrowser/#/R-DDI-6813720 NCEH1 hydrolyzes cholesterol esters IEA Dictyostelium discoideum 2718 R-DDI-8848053 https://reactome.org/PathwayBrowser/#/R-DDI-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Dictyostelium discoideum 2718 R-DDI-8876472 https://reactome.org/PathwayBrowser/#/R-DDI-8876472 NPC2 binds CHOL IEA Dictyostelium discoideum 2718 R-DDI-8876484 https://reactome.org/PathwayBrowser/#/R-DDI-8876484 NPC2 transfers CHOL to NPC1 IEA Dictyostelium discoideum 2718 R-DDI-8876485 https://reactome.org/PathwayBrowser/#/R-DDI-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Dictyostelium discoideum 2718 R-DDI-8937442 https://reactome.org/PathwayBrowser/#/R-DDI-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Dictyostelium discoideum 2718 R-DME-1454928 https://reactome.org/PathwayBrowser/#/R-DME-1454928 ABCG4 may mediate cholesterol efflux IEA Drosophila melanogaster 2718 R-DME-176609 https://reactome.org/PathwayBrowser/#/R-DME-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Drosophila melanogaster 2718 R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 2718 R-DME-209313 https://reactome.org/PathwayBrowser/#/R-DME-209313 Autocleavage of HH TAS Drosophila melanogaster 2718 R-DME-264695 https://reactome.org/PathwayBrowser/#/R-DME-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Drosophila melanogaster 2718 R-DME-265783 https://reactome.org/PathwayBrowser/#/R-DME-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Drosophila melanogaster 2718 R-DME-266082 https://reactome.org/PathwayBrowser/#/R-DME-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Drosophila melanogaster 2718 R-DME-5250531 https://reactome.org/PathwayBrowser/#/R-DME-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Drosophila melanogaster 2718 R-DME-5358340 https://reactome.org/PathwayBrowser/#/R-DME-5358340 Autoproteolytic cleavage of Hh precursors IEA Drosophila melanogaster 2718 R-DME-8876472 https://reactome.org/PathwayBrowser/#/R-DME-8876472 NPC2 binds CHOL IEA Drosophila melanogaster 2718 R-DME-8876484 https://reactome.org/PathwayBrowser/#/R-DME-8876484 NPC2 transfers CHOL to NPC1 IEA Drosophila melanogaster 2718 R-DME-8876485 https://reactome.org/PathwayBrowser/#/R-DME-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Drosophila melanogaster 2718 R-DME-8876696 https://reactome.org/PathwayBrowser/#/R-DME-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Drosophila melanogaster 2718 R-DME-8937442 https://reactome.org/PathwayBrowser/#/R-DME-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Drosophila melanogaster 2718 R-DME-8951850 https://reactome.org/PathwayBrowser/#/R-DME-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Drosophila melanogaster 2718 R-DRE-1454928 https://reactome.org/PathwayBrowser/#/R-DRE-1454928 ABCG4 may mediate cholesterol efflux IEA Danio rerio 2718 R-DRE-176609 https://reactome.org/PathwayBrowser/#/R-DRE-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Danio rerio 2718 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 2718 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 2718 R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 2718 R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 2718 R-DRE-196126 https://reactome.org/PathwayBrowser/#/R-DRE-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space IEA Danio rerio 2718 R-DRE-196417 https://reactome.org/PathwayBrowser/#/R-DRE-196417 Reduction of desmosterol to cholesterol IEA Danio rerio 2718 R-DRE-216723 https://reactome.org/PathwayBrowser/#/R-DRE-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Danio rerio 2718 R-DRE-216756 https://reactome.org/PathwayBrowser/#/R-DRE-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Danio rerio 2718 R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 2718 R-DRE-266082 https://reactome.org/PathwayBrowser/#/R-DRE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Danio rerio 2718 R-DRE-266089 https://reactome.org/PathwayBrowser/#/R-DRE-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Danio rerio 2718 R-DRE-266299 https://reactome.org/PathwayBrowser/#/R-DRE-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Danio rerio 2718 R-DRE-349657 https://reactome.org/PathwayBrowser/#/R-DRE-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Danio rerio 2718 R-DRE-5250531 https://reactome.org/PathwayBrowser/#/R-DRE-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Danio rerio 2718 R-DRE-5358340 https://reactome.org/PathwayBrowser/#/R-DRE-5358340 Autoproteolytic cleavage of Hh precursors IEA Danio rerio 2718 R-DRE-6807055 https://reactome.org/PathwayBrowser/#/R-DRE-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Danio rerio 2718 R-DRE-6813720 https://reactome.org/PathwayBrowser/#/R-DRE-6813720 NCEH1 hydrolyzes cholesterol esters IEA Danio rerio 2718 R-DRE-8876472 https://reactome.org/PathwayBrowser/#/R-DRE-8876472 NPC2 binds CHOL IEA Danio rerio 2718 R-DRE-8876696 https://reactome.org/PathwayBrowser/#/R-DRE-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Danio rerio 2718 R-DRE-8937442 https://reactome.org/PathwayBrowser/#/R-DRE-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Danio rerio 2718 R-GGA-1369028 https://reactome.org/PathwayBrowser/#/R-GGA-1369028 ABCAs mediate lipid efflux IEA Gallus gallus 2718 R-GGA-1369052 https://reactome.org/PathwayBrowser/#/R-GGA-1369052 ABCAs mediate lipid influx IEA Gallus gallus 2718 R-GGA-1454928 https://reactome.org/PathwayBrowser/#/R-GGA-1454928 ABCG4 may mediate cholesterol efflux IEA Gallus gallus 2718 R-GGA-174587 https://reactome.org/PathwayBrowser/#/R-GGA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Gallus gallus 2718 R-GGA-176609 https://reactome.org/PathwayBrowser/#/R-GGA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Gallus gallus 2718 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 2718 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 2718 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 2718 R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 2718 R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 2718 R-GGA-196126 https://reactome.org/PathwayBrowser/#/R-GGA-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space IEA Gallus gallus 2718 R-GGA-196417 https://reactome.org/PathwayBrowser/#/R-GGA-196417 Reduction of desmosterol to cholesterol IEA Gallus gallus 2718 R-GGA-216723 https://reactome.org/PathwayBrowser/#/R-GGA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Gallus gallus 2718 R-GGA-216756 https://reactome.org/PathwayBrowser/#/R-GGA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Gallus gallus 2718 R-GGA-2187332 https://reactome.org/PathwayBrowser/#/R-GGA-2187332 Cytosolic CMs translocate to extracellular region IEA Gallus gallus 2718 R-GGA-2197646 https://reactome.org/PathwayBrowser/#/R-GGA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Gallus gallus 2718 R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 2718 R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 2718 R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 2718 R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 2718 R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 2718 R-GGA-2395764 https://reactome.org/PathwayBrowser/#/R-GGA-2395764 atREs binds to nascent CM IEA Gallus gallus 2718 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 2718 R-GGA-2512800 https://reactome.org/PathwayBrowser/#/R-GGA-2512800 SCARB1:ligand is endocytosed IEA Gallus gallus 2718 R-GGA-264678 https://reactome.org/PathwayBrowser/#/R-GGA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Gallus gallus 2718 R-GGA-264689 https://reactome.org/PathwayBrowser/#/R-GGA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Gallus gallus 2718 R-GGA-264695 https://reactome.org/PathwayBrowser/#/R-GGA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Gallus gallus 2718 R-GGA-265783 https://reactome.org/PathwayBrowser/#/R-GGA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Gallus gallus 2718 R-GGA-266082 https://reactome.org/PathwayBrowser/#/R-GGA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Gallus gallus 2718 R-GGA-266089 https://reactome.org/PathwayBrowser/#/R-GGA-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Gallus gallus 2718 R-GGA-266299 https://reactome.org/PathwayBrowser/#/R-GGA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Gallus gallus 2718 R-GGA-266310 https://reactome.org/PathwayBrowser/#/R-GGA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Gallus gallus 2718 R-GGA-266315 https://reactome.org/PathwayBrowser/#/R-GGA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Gallus gallus 2718 R-GGA-266328 https://reactome.org/PathwayBrowser/#/R-GGA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol IEA Gallus gallus 2718 R-GGA-266350 https://reactome.org/PathwayBrowser/#/R-GGA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester IEA Gallus gallus 2718 R-GGA-349404 https://reactome.org/PathwayBrowser/#/R-GGA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex IEA Gallus gallus 2718 R-GGA-349637 https://reactome.org/PathwayBrowser/#/R-GGA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Gallus gallus 2718 R-GGA-349638 https://reactome.org/PathwayBrowser/#/R-GGA-349638 Disassembly of SR-BI-bound spherical HDL IEA Gallus gallus 2718 R-GGA-349657 https://reactome.org/PathwayBrowser/#/R-GGA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Gallus gallus 2718 R-GGA-432121 https://reactome.org/PathwayBrowser/#/R-GGA-432121 LDL binds to LRP8 IEA Gallus gallus 2718 R-GGA-432129 https://reactome.org/PathwayBrowser/#/R-GGA-432129 FGR binds and phosphorylates LRP8 IEA Gallus gallus 2718 R-GGA-435244 https://reactome.org/PathwayBrowser/#/R-GGA-435244 PECAM1 is phosphorylated IEA Gallus gallus 2718 R-GGA-5250531 https://reactome.org/PathwayBrowser/#/R-GGA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Gallus gallus 2718 R-GGA-5358340 https://reactome.org/PathwayBrowser/#/R-GGA-5358340 Autoproteolytic cleavage of Hh precursors IEA Gallus gallus 2718 R-GGA-6807055 https://reactome.org/PathwayBrowser/#/R-GGA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Gallus gallus 2718 R-GGA-6813720 https://reactome.org/PathwayBrowser/#/R-GGA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Gallus gallus 2718 R-GGA-8848053 https://reactome.org/PathwayBrowser/#/R-GGA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Gallus gallus 2718 R-GGA-8858252 https://reactome.org/PathwayBrowser/#/R-GGA-8858252 HDLBP binds HDL IEA Gallus gallus 2718 R-GGA-8865667 https://reactome.org/PathwayBrowser/#/R-GGA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Gallus gallus 2718 R-GGA-8866304 https://reactome.org/PathwayBrowser/#/R-GGA-8866304 pre-VLDL binds lipids to form VLDL IEA Gallus gallus 2718 R-GGA-8866327 https://reactome.org/PathwayBrowser/#/R-GGA-8866327 VLDL translocates from SER lumen to extracellular region IEA Gallus gallus 2718 R-GGA-8869667 https://reactome.org/PathwayBrowser/#/R-GGA-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Gallus gallus 2718 R-GGA-8876366 https://reactome.org/PathwayBrowser/#/R-GGA-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Gallus gallus 2718 R-GGA-8876472 https://reactome.org/PathwayBrowser/#/R-GGA-8876472 NPC2 binds CHOL IEA Gallus gallus 2718 R-GGA-8876484 https://reactome.org/PathwayBrowser/#/R-GGA-8876484 NPC2 transfers CHOL to NPC1 IEA Gallus gallus 2718 R-GGA-8876485 https://reactome.org/PathwayBrowser/#/R-GGA-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Gallus gallus 2718 R-GGA-8876696 https://reactome.org/PathwayBrowser/#/R-GGA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Gallus gallus 2718 R-GGA-8937442 https://reactome.org/PathwayBrowser/#/R-GGA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Gallus gallus 2718 R-GGA-8948034 https://reactome.org/PathwayBrowser/#/R-GGA-8948034 FGR binds LDL:LRP8 IEA Gallus gallus 2718 R-GGA-8951850 https://reactome.org/PathwayBrowser/#/R-GGA-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Gallus gallus 2718 R-GGA-9707586 https://reactome.org/PathwayBrowser/#/R-GGA-9707586 FeHM oxidises LDL,HDL IEA Gallus gallus 2718 R-HSA-1369028 https://reactome.org/PathwayBrowser/#/R-HSA-1369028 ABCAs mediate lipid efflux TAS Homo sapiens 2718 R-HSA-1369052 https://reactome.org/PathwayBrowser/#/R-HSA-1369052 ABCAs mediate lipid influx TAS Homo sapiens 2718 R-HSA-1454928 https://reactome.org/PathwayBrowser/#/R-HSA-1454928 ABCG4 may mediate cholesterol efflux TAS Homo sapiens 2718 R-HSA-163432 https://reactome.org/PathwayBrowser/#/R-HSA-163432 cholesterol ester + H2O -> cholesterol + fatty acid IEA Homo sapiens 2718 R-HSA-171059 https://reactome.org/PathwayBrowser/#/R-HSA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] TAS Homo sapiens 2718 R-HSA-171106 https://reactome.org/PathwayBrowser/#/R-HSA-171106 LDLR:LDL complex => LDLR + LDL TAS Homo sapiens 2718 R-HSA-171122 https://reactome.org/PathwayBrowser/#/R-HSA-171122 LDL + LDLR => LDL:LDLR complex TAS Homo sapiens 2718 R-HSA-171141 https://reactome.org/PathwayBrowser/#/R-HSA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) TAS Homo sapiens 2718 R-HSA-174587 https://reactome.org/PathwayBrowser/#/R-HSA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] TAS Homo sapiens 2718 R-HSA-174624 https://reactome.org/PathwayBrowser/#/R-HSA-174624 chylomicron remnant:apoE:LDLR complex => chylomicron remnant:apoE + LDLR IEA Homo sapiens 2718 R-HSA-174657 https://reactome.org/PathwayBrowser/#/R-HSA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex TAS Homo sapiens 2718 R-HSA-174660 https://reactome.org/PathwayBrowser/#/R-HSA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron TAS Homo sapiens 2718 R-HSA-174690 https://reactome.org/PathwayBrowser/#/R-HSA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III TAS Homo sapiens 2718 R-HSA-174706 https://reactome.org/PathwayBrowser/#/R-HSA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) TAS Homo sapiens 2718 R-HSA-174739 https://reactome.org/PathwayBrowser/#/R-HSA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex TAS Homo sapiens 2718 R-HSA-174741 https://reactome.org/PathwayBrowser/#/R-HSA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron TAS Homo sapiens 2718 R-HSA-174757 https://reactome.org/PathwayBrowser/#/R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols TAS Homo sapiens 2718 R-HSA-174808 https://reactome.org/PathwayBrowser/#/R-HSA-174808 chylomicron remnant:apoE:LDLR complex [coated vesicle membrane] => chylomicron remnant:apoE:LDLR complex [endosome membrane] IEA Homo sapiens 2718 R-HSA-176609 https://reactome.org/PathwayBrowser/#/R-HSA-176609 cholesterol + PAPS => cholesterol sulfate + PAP TAS Homo sapiens 2718 R-HSA-176879 https://reactome.org/PathwayBrowser/#/R-HSA-176879 apolipoprotein(a) + LDL => Lp(a) TAS Homo sapiens 2718 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 2718 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 2718 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 2718 R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 2718 R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 2718 R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 2718 R-HSA-196126 https://reactome.org/PathwayBrowser/#/R-HSA-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space TAS Homo sapiens 2718 R-HSA-196417 https://reactome.org/PathwayBrowser/#/R-HSA-196417 Reduction of desmosterol to cholesterol TAS Homo sapiens 2718 R-HSA-203130 https://reactome.org/PathwayBrowser/#/R-HSA-203130 OLR1 binds to oxidized LDL TAS Homo sapiens 2718 R-HSA-216723 https://reactome.org/PathwayBrowser/#/R-HSA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 2718 R-HSA-216756 https://reactome.org/PathwayBrowser/#/R-HSA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle TAS Homo sapiens 2718 R-HSA-2168889 https://reactome.org/PathwayBrowser/#/R-HSA-2168889 Haptoglobin-related Protein binds Hemoglobin TAS Homo sapiens 2718 R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 2718 R-HSA-2187261 https://reactome.org/PathwayBrowser/#/R-HSA-2187261 COLEC12 (SCARA4) binds ligands TAS Homo sapiens 2718 R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 2718 R-HSA-2187332 https://reactome.org/PathwayBrowser/#/R-HSA-2187332 Cytosolic CMs translocate to extracellular region TAS Homo sapiens 2718 R-HSA-2197645 https://reactome.org/PathwayBrowser/#/R-HSA-2197645 SCARF1 (SREC-I) binds ligands IEA Homo sapiens 2718 R-HSA-2197646 https://reactome.org/PathwayBrowser/#/R-HSA-2197646 SCARB1 (SR-BI, CLA-1) binds ligands TAS Homo sapiens 2718 R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 2718 R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 2718 R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 2718 R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 2718 R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 2718 R-HSA-2247514 https://reactome.org/PathwayBrowser/#/R-HSA-2247514 SCARF1:ligand is endocytosed TAS Homo sapiens 2718 R-HSA-2317530 https://reactome.org/PathwayBrowser/#/R-HSA-2317530 SREBP1A,1C,2 binds SCAP:cholesterol:INSIG and is retained in the endoplasmic reticulum IEA Homo sapiens 2718 R-HSA-2395764 https://reactome.org/PathwayBrowser/#/R-HSA-2395764 atREs binds to nascent CM TAS Homo sapiens 2718 R-HSA-2395768 https://reactome.org/PathwayBrowser/#/R-HSA-2395768 LPL hydrolyses TGs from mature CMs TAS Homo sapiens 2718 R-HSA-2395784 https://reactome.org/PathwayBrowser/#/R-HSA-2395784 Nascent CMs transform into mature CMs TAS Homo sapiens 2718 R-HSA-2404131 https://reactome.org/PathwayBrowser/#/R-HSA-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol TAS Homo sapiens 2718 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 2718 R-HSA-2423785 https://reactome.org/PathwayBrowser/#/R-HSA-2423785 CR:atREs binds apoE and HSPG TAS Homo sapiens 2718 R-HSA-2424254 https://reactome.org/PathwayBrowser/#/R-HSA-2424254 LDLR transports extracellular CR:atREs to cytosol IEA Homo sapiens 2718 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 2718 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 2718 R-HSA-2512800 https://reactome.org/PathwayBrowser/#/R-HSA-2512800 SCARB1:ligand is endocytosed TAS Homo sapiens 2718 R-HSA-264678 https://reactome.org/PathwayBrowser/#/R-HSA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex TAS Homo sapiens 2718 R-HSA-264689 https://reactome.org/PathwayBrowser/#/R-HSA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL TAS Homo sapiens 2718 R-HSA-264695 https://reactome.org/PathwayBrowser/#/R-HSA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) TAS Homo sapiens 2718 R-HSA-265443 https://reactome.org/PathwayBrowser/#/R-HSA-265443 NPC1L1-mediated cholesterol uptake IEA Homo sapiens 2718 R-HSA-265783 https://reactome.org/PathwayBrowser/#/R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region TAS Homo sapiens 2718 R-HSA-266082 https://reactome.org/PathwayBrowser/#/R-HSA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface TAS Homo sapiens 2718 R-HSA-266089 https://reactome.org/PathwayBrowser/#/R-HSA-266089 Discoidal HDL binds membrane-associated free cholesterol TAS Homo sapiens 2718 R-HSA-266299 https://reactome.org/PathwayBrowser/#/R-HSA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids TAS Homo sapiens 2718 R-HSA-266303 https://reactome.org/PathwayBrowser/#/R-HSA-266303 Spherical HDL binds C and E apolipoproteins TAS Homo sapiens 2718 R-HSA-266310 https://reactome.org/PathwayBrowser/#/R-HSA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL TAS Homo sapiens 2718 R-HSA-266315 https://reactome.org/PathwayBrowser/#/R-HSA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex TAS Homo sapiens 2718 R-HSA-266328 https://reactome.org/PathwayBrowser/#/R-HSA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol TAS Homo sapiens 2718 R-HSA-266350 https://reactome.org/PathwayBrowser/#/R-HSA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester TAS Homo sapiens 2718 R-HSA-2981040 https://reactome.org/PathwayBrowser/#/R-HSA-2981040 COLEC12:ligand is endocytosed TAS Homo sapiens 2718 R-HSA-349404 https://reactome.org/PathwayBrowser/#/R-HSA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex TAS Homo sapiens 2718 R-HSA-349637 https://reactome.org/PathwayBrowser/#/R-HSA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface TAS Homo sapiens 2718 R-HSA-349638 https://reactome.org/PathwayBrowser/#/R-HSA-349638 Disassembly of SR-BI-bound spherical HDL TAS Homo sapiens 2718 R-HSA-349657 https://reactome.org/PathwayBrowser/#/R-HSA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle TAS Homo sapiens 2718 R-HSA-432121 https://reactome.org/PathwayBrowser/#/R-HSA-432121 LDL binds to LRP8 TAS Homo sapiens 2718 R-HSA-432129 https://reactome.org/PathwayBrowser/#/R-HSA-432129 FGR binds and phosphorylates LRP8 TAS Homo sapiens 2718 R-HSA-435244 https://reactome.org/PathwayBrowser/#/R-HSA-435244 PECAM1 is phosphorylated TAS Homo sapiens 2718 R-HSA-5250531 https://reactome.org/PathwayBrowser/#/R-HSA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane TAS Homo sapiens 2718 R-HSA-5358340 https://reactome.org/PathwayBrowser/#/R-HSA-5358340 Autoproteolytic cleavage of Hh precursors TAS Homo sapiens 2718 R-HSA-5358460 https://reactome.org/PathwayBrowser/#/R-HSA-5358460 HPE SHH variants don't undergo autoproteolytic cleavage TAS Homo sapiens 2718 R-HSA-5679101 https://reactome.org/PathwayBrowser/#/R-HSA-5679101 Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 2718 R-HSA-5679145 https://reactome.org/PathwayBrowser/#/R-HSA-5679145 Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 2718 R-HSA-5682111 https://reactome.org/PathwayBrowser/#/R-HSA-5682111 Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 2718 R-HSA-6807055 https://reactome.org/PathwayBrowser/#/R-HSA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL TAS Homo sapiens 2718 R-HSA-6810937 https://reactome.org/PathwayBrowser/#/R-HSA-6810937 Lamellar bodies bind the early cornified envelope TAS Homo sapiens 2718 R-HSA-6813720 https://reactome.org/PathwayBrowser/#/R-HSA-6813720 NCEH1 hydrolyzes cholesterol esters TAS Homo sapiens 2718 R-HSA-6814298 https://reactome.org/PathwayBrowser/#/R-HSA-6814298 Late envelope proteins bind cornified envelope:CDSN TAS Homo sapiens 2718 R-HSA-6814387 https://reactome.org/PathwayBrowser/#/R-HSA-6814387 CASP14 cleaves filaggrin TAS Homo sapiens 2718 R-HSA-6814734 https://reactome.org/PathwayBrowser/#/R-HSA-6814734 CDSN binds the cornified envelope TAS Homo sapiens 2718 R-HSA-6814764 https://reactome.org/PathwayBrowser/#/R-HSA-6814764 Plasma membrane resorption TAS Homo sapiens 2718 R-HSA-8848053 https://reactome.org/PathwayBrowser/#/R-HSA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol TAS Homo sapiens 2718 R-HSA-8854408 https://reactome.org/PathwayBrowser/#/R-HSA-8854408 APOBR dimer binds VLDLs TAS Homo sapiens 2718 R-HSA-8854462 https://reactome.org/PathwayBrowser/#/R-HSA-8854462 VLDLR binds VLDL TAS Homo sapiens 2718 R-HSA-8858252 https://reactome.org/PathwayBrowser/#/R-HSA-8858252 HDLBP binds HDL TAS Homo sapiens 2718 R-HSA-8863471 https://reactome.org/PathwayBrowser/#/R-HSA-8863471 LDLR is bound by DAB2 and ARH TAS Homo sapiens 2718 R-HSA-8865667 https://reactome.org/PathwayBrowser/#/R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids TAS Homo sapiens 2718 R-HSA-8866304 https://reactome.org/PathwayBrowser/#/R-HSA-8866304 pre-VLDL binds lipids to form VLDL TAS Homo sapiens 2718 R-HSA-8866321 https://reactome.org/PathwayBrowser/#/R-HSA-8866321 VLDL binds APOC1 and APOC4 TAS Homo sapiens 2718 R-HSA-8866327 https://reactome.org/PathwayBrowser/#/R-HSA-8866327 VLDL translocates from SER lumen to extracellular region TAS Homo sapiens 2718 R-HSA-8867754 https://reactome.org/PathwayBrowser/#/R-HSA-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit TAS Homo sapiens 2718 R-HSA-8867756 https://reactome.org/PathwayBrowser/#/R-HSA-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit TAS Homo sapiens 2718 R-HSA-8868071 https://reactome.org/PathwayBrowser/#/R-HSA-8868071 Clathrin recruits PIK3C2A TAS Homo sapiens 2718 R-HSA-8868072 https://reactome.org/PathwayBrowser/#/R-HSA-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 TAS Homo sapiens 2718 R-HSA-8868230 https://reactome.org/PathwayBrowser/#/R-HSA-8868230 SNX9 recruits components of the actin polymerizing machinery TAS Homo sapiens 2718 R-HSA-8868236 https://reactome.org/PathwayBrowser/#/R-HSA-8868236 BAR domain proteins recruit dynamin TAS Homo sapiens 2718 R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 2718 R-HSA-8868651 https://reactome.org/PathwayBrowser/#/R-HSA-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit TAS Homo sapiens 2718 R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 2718 R-HSA-8868659 https://reactome.org/PathwayBrowser/#/R-HSA-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle TAS Homo sapiens 2718 R-HSA-8868660 https://reactome.org/PathwayBrowser/#/R-HSA-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle TAS Homo sapiens 2718 R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 2718 R-HSA-8869438 https://reactome.org/PathwayBrowser/#/R-HSA-8869438 Dissociation of clathrin-associated proteins TAS Homo sapiens 2718 R-HSA-8869667 https://reactome.org/PathwayBrowser/#/R-HSA-8869667 oxLDL:CD36 binds TLR4:TLR6 TAS Homo sapiens 2718 R-HSA-8871193 https://reactome.org/PathwayBrowser/#/R-HSA-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 TAS Homo sapiens 2718 R-HSA-8871194 https://reactome.org/PathwayBrowser/#/R-HSA-8871194 RAB5 and GAPVD1 bind AP-2 TAS Homo sapiens 2718 R-HSA-8876366 https://reactome.org/PathwayBrowser/#/R-HSA-8876366 LDL translocates from endosome lumen to lysosome lumen TAS Homo sapiens 2718 R-HSA-8876472 https://reactome.org/PathwayBrowser/#/R-HSA-8876472 NPC2 binds CHOL TAS Homo sapiens 2718 R-HSA-8876484 https://reactome.org/PathwayBrowser/#/R-HSA-8876484 NPC2 transfers CHOL to NPC1 TAS Homo sapiens 2718 R-HSA-8876485 https://reactome.org/PathwayBrowser/#/R-HSA-8876485 CHOL translocates from lysosome membrane to ER membrane TAS Homo sapiens 2718 R-HSA-8876696 https://reactome.org/PathwayBrowser/#/R-HSA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST TAS Homo sapiens 2718 R-HSA-8933258 https://reactome.org/PathwayBrowser/#/R-HSA-8933258 LSR trimer binds LDL IEA Homo sapiens 2718 R-HSA-8933292 https://reactome.org/PathwayBrowser/#/R-HSA-8933292 LSR trimer binds VLDL IEA Homo sapiens 2718 R-HSA-8937442 https://reactome.org/PathwayBrowser/#/R-HSA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) TAS Homo sapiens 2718 R-HSA-8948034 https://reactome.org/PathwayBrowser/#/R-HSA-8948034 FGR binds LDL:LRP8 TAS Homo sapiens 2718 R-HSA-8951850 https://reactome.org/PathwayBrowser/#/R-HSA-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane TAS Homo sapiens 2718 R-HSA-9707586 https://reactome.org/PathwayBrowser/#/R-HSA-9707586 FeHM oxidises LDL,HDL TAS Homo sapiens 2718 R-MMU-1369028 https://reactome.org/PathwayBrowser/#/R-MMU-1369028 ABCAs mediate lipid efflux IEA Mus musculus 2718 R-MMU-1369052 https://reactome.org/PathwayBrowser/#/R-MMU-1369052 ABCAs mediate lipid influx IEA Mus musculus 2718 R-MMU-1454928 https://reactome.org/PathwayBrowser/#/R-MMU-1454928 ABCG4 may mediate cholesterol efflux IEA Mus musculus 2718 R-MMU-171059 https://reactome.org/PathwayBrowser/#/R-MMU-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Mus musculus 2718 R-MMU-171106 https://reactome.org/PathwayBrowser/#/R-MMU-171106 LDLR:LDL complex => LDLR + LDL IEA Mus musculus 2718 R-MMU-171122 https://reactome.org/PathwayBrowser/#/R-MMU-171122 LDL + LDLR => LDL:LDLR complex IEA Mus musculus 2718 R-MMU-171141 https://reactome.org/PathwayBrowser/#/R-MMU-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Mus musculus 2718 R-MMU-174587 https://reactome.org/PathwayBrowser/#/R-MMU-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Mus musculus 2718 R-MMU-174657 https://reactome.org/PathwayBrowser/#/R-MMU-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Mus musculus 2718 R-MMU-174660 https://reactome.org/PathwayBrowser/#/R-MMU-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Mus musculus 2718 R-MMU-174690 https://reactome.org/PathwayBrowser/#/R-MMU-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Mus musculus 2718 R-MMU-174706 https://reactome.org/PathwayBrowser/#/R-MMU-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Mus musculus 2718 R-MMU-174739 https://reactome.org/PathwayBrowser/#/R-MMU-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Mus musculus 2718 R-MMU-174741 https://reactome.org/PathwayBrowser/#/R-MMU-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Mus musculus 2718 R-MMU-174757 https://reactome.org/PathwayBrowser/#/R-MMU-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Mus musculus 2718 R-MMU-176609 https://reactome.org/PathwayBrowser/#/R-MMU-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Mus musculus 2718 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 2718 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 2718 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 2718 R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 2718 R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 2718 R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 2718 R-MMU-196126 https://reactome.org/PathwayBrowser/#/R-MMU-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space IEA Mus musculus 2718 R-MMU-196417 https://reactome.org/PathwayBrowser/#/R-MMU-196417 Reduction of desmosterol to cholesterol IEA Mus musculus 2718 R-MMU-203130 https://reactome.org/PathwayBrowser/#/R-MMU-203130 OLR1 binds to oxidized LDL IEA Mus musculus 2718 R-MMU-216723 https://reactome.org/PathwayBrowser/#/R-MMU-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Mus musculus 2718 R-MMU-216756 https://reactome.org/PathwayBrowser/#/R-MMU-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Mus musculus 2718 R-MMU-2168889 https://reactome.org/PathwayBrowser/#/R-MMU-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Mus musculus 2718 R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 2718 R-MMU-2173783 https://reactome.org/PathwayBrowser/#/R-MMU-2173783 Marco binds ligands TAS Mus musculus 2718 R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 2718 R-MMU-2187332 https://reactome.org/PathwayBrowser/#/R-MMU-2187332 Cytosolic CMs translocate to extracellular region IEA Mus musculus 2718 R-MMU-2197646 https://reactome.org/PathwayBrowser/#/R-MMU-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Mus musculus 2718 R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 2718 R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 2718 R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 2718 R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 2718 R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 2718 R-MMU-2395764 https://reactome.org/PathwayBrowser/#/R-MMU-2395764 atREs binds to nascent CM IEA Mus musculus 2718 R-MMU-2395768 https://reactome.org/PathwayBrowser/#/R-MMU-2395768 LPL hydrolyses TGs from mature CMs IEA Mus musculus 2718 R-MMU-2395784 https://reactome.org/PathwayBrowser/#/R-MMU-2395784 Nascent CMs transform into mature CMs IEA Mus musculus 2718 R-MMU-2404131 https://reactome.org/PathwayBrowser/#/R-MMU-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Mus musculus 2718 R-MMU-2423785 https://reactome.org/PathwayBrowser/#/R-MMU-2423785 CR:atREs binds apoE and HSPG IEA Mus musculus 2718 R-MMU-2425403 https://reactome.org/PathwayBrowser/#/R-MMU-2425403 Extracellular CR:atREs are transported to cytosol by Ldlr TAS Mus musculus 2718 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 2718 R-MMU-2512800 https://reactome.org/PathwayBrowser/#/R-MMU-2512800 SCARB1:ligand is endocytosed IEA Mus musculus 2718 R-MMU-264678 https://reactome.org/PathwayBrowser/#/R-MMU-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Mus musculus 2718 R-MMU-264689 https://reactome.org/PathwayBrowser/#/R-MMU-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Mus musculus 2718 R-MMU-264695 https://reactome.org/PathwayBrowser/#/R-MMU-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Mus musculus 2718 R-MMU-265783 https://reactome.org/PathwayBrowser/#/R-MMU-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Mus musculus 2718 R-MMU-266082 https://reactome.org/PathwayBrowser/#/R-MMU-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Mus musculus 2718 R-MMU-266089 https://reactome.org/PathwayBrowser/#/R-MMU-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Mus musculus 2718 R-MMU-266299 https://reactome.org/PathwayBrowser/#/R-MMU-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Mus musculus 2718 R-MMU-266303 https://reactome.org/PathwayBrowser/#/R-MMU-266303 Spherical HDL binds C and E apolipoproteins IEA Mus musculus 2718 R-MMU-266310 https://reactome.org/PathwayBrowser/#/R-MMU-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Mus musculus 2718 R-MMU-266315 https://reactome.org/PathwayBrowser/#/R-MMU-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Mus musculus 2718 R-MMU-349637 https://reactome.org/PathwayBrowser/#/R-MMU-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Mus musculus 2718 R-MMU-349638 https://reactome.org/PathwayBrowser/#/R-MMU-349638 Disassembly of SR-BI-bound spherical HDL IEA Mus musculus 2718 R-MMU-349657 https://reactome.org/PathwayBrowser/#/R-MMU-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Mus musculus 2718 R-MMU-432121 https://reactome.org/PathwayBrowser/#/R-MMU-432121 LDL binds to LRP8 IEA Mus musculus 2718 R-MMU-432129 https://reactome.org/PathwayBrowser/#/R-MMU-432129 FGR binds and phosphorylates LRP8 IEA Mus musculus 2718 R-MMU-435244 https://reactome.org/PathwayBrowser/#/R-MMU-435244 PECAM1 is phosphorylated IEA Mus musculus 2718 R-MMU-5250531 https://reactome.org/PathwayBrowser/#/R-MMU-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Mus musculus 2718 R-MMU-5358340 https://reactome.org/PathwayBrowser/#/R-MMU-5358340 Autoproteolytic cleavage of Hh precursors IEA Mus musculus 2718 R-MMU-6807055 https://reactome.org/PathwayBrowser/#/R-MMU-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Mus musculus 2718 R-MMU-6810937 https://reactome.org/PathwayBrowser/#/R-MMU-6810937 Lamellar bodies bind the early cornified envelope IEA Mus musculus 2718 R-MMU-6813720 https://reactome.org/PathwayBrowser/#/R-MMU-6813720 NCEH1 hydrolyzes cholesterol esters IEA Mus musculus 2718 R-MMU-6814387 https://reactome.org/PathwayBrowser/#/R-MMU-6814387 CASP14 cleaves filaggrin IEA Mus musculus 2718 R-MMU-6814734 https://reactome.org/PathwayBrowser/#/R-MMU-6814734 CDSN binds the cornified envelope IEA Mus musculus 2718 R-MMU-6814764 https://reactome.org/PathwayBrowser/#/R-MMU-6814764 Plasma membrane resorption IEA Mus musculus 2718 R-MMU-8848053 https://reactome.org/PathwayBrowser/#/R-MMU-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Mus musculus 2718 R-MMU-8854408 https://reactome.org/PathwayBrowser/#/R-MMU-8854408 APOBR dimer binds VLDLs IEA Mus musculus 2718 R-MMU-8854462 https://reactome.org/PathwayBrowser/#/R-MMU-8854462 VLDLR binds VLDL IEA Mus musculus 2718 R-MMU-8858252 https://reactome.org/PathwayBrowser/#/R-MMU-8858252 HDLBP binds HDL IEA Mus musculus 2718 R-MMU-8863471 https://reactome.org/PathwayBrowser/#/R-MMU-8863471 LDLR is bound by DAB2 and ARH IEA Mus musculus 2718 R-MMU-8865667 https://reactome.org/PathwayBrowser/#/R-MMU-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Mus musculus 2718 R-MMU-8866304 https://reactome.org/PathwayBrowser/#/R-MMU-8866304 pre-VLDL binds lipids to form VLDL IEA Mus musculus 2718 R-MMU-8866321 https://reactome.org/PathwayBrowser/#/R-MMU-8866321 VLDL binds APOC1 and APOC4 IEA Mus musculus 2718 R-MMU-8866327 https://reactome.org/PathwayBrowser/#/R-MMU-8866327 VLDL translocates from SER lumen to extracellular region IEA Mus musculus 2718 R-MMU-8867754 https://reactome.org/PathwayBrowser/#/R-MMU-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Mus musculus 2718 R-MMU-8867756 https://reactome.org/PathwayBrowser/#/R-MMU-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Mus musculus 2718 R-MMU-8868071 https://reactome.org/PathwayBrowser/#/R-MMU-8868071 Clathrin recruits PIK3C2A IEA Mus musculus 2718 R-MMU-8868072 https://reactome.org/PathwayBrowser/#/R-MMU-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Mus musculus 2718 R-MMU-8868236 https://reactome.org/PathwayBrowser/#/R-MMU-8868236 BAR domain proteins recruit dynamin IEA Mus musculus 2718 R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 2718 R-MMU-8868651 https://reactome.org/PathwayBrowser/#/R-MMU-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Mus musculus 2718 R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 2718 R-MMU-8868659 https://reactome.org/PathwayBrowser/#/R-MMU-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Mus musculus 2718 R-MMU-8868660 https://reactome.org/PathwayBrowser/#/R-MMU-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Mus musculus 2718 R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 2718 R-MMU-8869667 https://reactome.org/PathwayBrowser/#/R-MMU-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Mus musculus 2718 R-MMU-8871193 https://reactome.org/PathwayBrowser/#/R-MMU-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Mus musculus 2718 R-MMU-8871194 https://reactome.org/PathwayBrowser/#/R-MMU-8871194 RAB5 and GAPVD1 bind AP-2 IEA Mus musculus 2718 R-MMU-8876366 https://reactome.org/PathwayBrowser/#/R-MMU-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Mus musculus 2718 R-MMU-8876472 https://reactome.org/PathwayBrowser/#/R-MMU-8876472 NPC2 binds CHOL IEA Mus musculus 2718 R-MMU-8876484 https://reactome.org/PathwayBrowser/#/R-MMU-8876484 NPC2 transfers CHOL to NPC1 IEA Mus musculus 2718 R-MMU-8876485 https://reactome.org/PathwayBrowser/#/R-MMU-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Mus musculus 2718 R-MMU-8876696 https://reactome.org/PathwayBrowser/#/R-MMU-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Mus musculus 2718 R-MMU-8933256 https://reactome.org/PathwayBrowser/#/R-MMU-8933256 Lsr trimer binds LDL TAS Mus musculus 2718 R-MMU-8933295 https://reactome.org/PathwayBrowser/#/R-MMU-8933295 Lsr trimer binds VLDL TAS Mus musculus 2718 R-MMU-8937442 https://reactome.org/PathwayBrowser/#/R-MMU-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Mus musculus 2718 R-MMU-8948034 https://reactome.org/PathwayBrowser/#/R-MMU-8948034 FGR binds LDL:LRP8 IEA Mus musculus 2718 R-MMU-8951850 https://reactome.org/PathwayBrowser/#/R-MMU-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Mus musculus 2718 R-MMU-9707586 https://reactome.org/PathwayBrowser/#/R-MMU-9707586 FeHM oxidises LDL,HDL IEA Mus musculus 2718 R-NUL-2317526 https://reactome.org/PathwayBrowser/#/R-NUL-2317526 SREBP1A/1C/2 is retained in the endoplasmic reticulum by SCAP:cholesterol:INSIG TAS Cricetulus griseus 2718 R-PFA-1369028 https://reactome.org/PathwayBrowser/#/R-PFA-1369028 ABCAs mediate lipid efflux IEA Plasmodium falciparum 2718 R-PFA-1369052 https://reactome.org/PathwayBrowser/#/R-PFA-1369052 ABCAs mediate lipid influx IEA Plasmodium falciparum 2718 R-PFA-265783 https://reactome.org/PathwayBrowser/#/R-PFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Plasmodium falciparum 2718 R-PFA-5250531 https://reactome.org/PathwayBrowser/#/R-PFA-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Plasmodium falciparum 2718 R-PFA-8848053 https://reactome.org/PathwayBrowser/#/R-PFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Plasmodium falciparum 2718 R-RNO-1369028 https://reactome.org/PathwayBrowser/#/R-RNO-1369028 ABCAs mediate lipid efflux IEA Rattus norvegicus 2718 R-RNO-1369052 https://reactome.org/PathwayBrowser/#/R-RNO-1369052 ABCAs mediate lipid influx IEA Rattus norvegicus 2718 R-RNO-1454928 https://reactome.org/PathwayBrowser/#/R-RNO-1454928 ABCG4 may mediate cholesterol efflux IEA Rattus norvegicus 2718 R-RNO-163407 https://reactome.org/PathwayBrowser/#/R-RNO-163407 cholesterol ester + H2O -> cholesterol + fatty acid TAS Rattus norvegicus 2718 R-RNO-171059 https://reactome.org/PathwayBrowser/#/R-RNO-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Rattus norvegicus 2718 R-RNO-171106 https://reactome.org/PathwayBrowser/#/R-RNO-171106 LDLR:LDL complex => LDLR + LDL IEA Rattus norvegicus 2718 R-RNO-171122 https://reactome.org/PathwayBrowser/#/R-RNO-171122 LDL + LDLR => LDL:LDLR complex IEA Rattus norvegicus 2718 R-RNO-171141 https://reactome.org/PathwayBrowser/#/R-RNO-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Rattus norvegicus 2718 R-RNO-174587 https://reactome.org/PathwayBrowser/#/R-RNO-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Rattus norvegicus 2718 R-RNO-174657 https://reactome.org/PathwayBrowser/#/R-RNO-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Rattus norvegicus 2718 R-RNO-174660 https://reactome.org/PathwayBrowser/#/R-RNO-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Rattus norvegicus 2718 R-RNO-174690 https://reactome.org/PathwayBrowser/#/R-RNO-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Rattus norvegicus 2718 R-RNO-174706 https://reactome.org/PathwayBrowser/#/R-RNO-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Rattus norvegicus 2718 R-RNO-174739 https://reactome.org/PathwayBrowser/#/R-RNO-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Rattus norvegicus 2718 R-RNO-174741 https://reactome.org/PathwayBrowser/#/R-RNO-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Rattus norvegicus 2718 R-RNO-174757 https://reactome.org/PathwayBrowser/#/R-RNO-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Rattus norvegicus 2718 R-RNO-176609 https://reactome.org/PathwayBrowser/#/R-RNO-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Rattus norvegicus 2718 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 2718 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 2718 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 2718 R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 2718 R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 2718 R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 2718 R-RNO-196126 https://reactome.org/PathwayBrowser/#/R-RNO-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space IEA Rattus norvegicus 2718 R-RNO-196417 https://reactome.org/PathwayBrowser/#/R-RNO-196417 Reduction of desmosterol to cholesterol IEA Rattus norvegicus 2718 R-RNO-203130 https://reactome.org/PathwayBrowser/#/R-RNO-203130 OLR1 binds to oxidized LDL IEA Rattus norvegicus 2718 R-RNO-216723 https://reactome.org/PathwayBrowser/#/R-RNO-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 2718 R-RNO-216756 https://reactome.org/PathwayBrowser/#/R-RNO-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Rattus norvegicus 2718 R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus 2718 R-RNO-2187332 https://reactome.org/PathwayBrowser/#/R-RNO-2187332 Cytosolic CMs translocate to extracellular region IEA Rattus norvegicus 2718 R-RNO-2197646 https://reactome.org/PathwayBrowser/#/R-RNO-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Rattus norvegicus 2718 R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 2718 R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 2718 R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 2718 R-RNO-2395764 https://reactome.org/PathwayBrowser/#/R-RNO-2395764 atREs binds to nascent CM IEA Rattus norvegicus 2718 R-RNO-2395768 https://reactome.org/PathwayBrowser/#/R-RNO-2395768 LPL hydrolyses TGs from mature CMs IEA Rattus norvegicus 2718 R-RNO-2395784 https://reactome.org/PathwayBrowser/#/R-RNO-2395784 Nascent CMs transform into mature CMs IEA Rattus norvegicus 2718 R-RNO-2404131 https://reactome.org/PathwayBrowser/#/R-RNO-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Rattus norvegicus 2718 R-RNO-2423785 https://reactome.org/PathwayBrowser/#/R-RNO-2423785 CR:atREs binds apoE and HSPG IEA Rattus norvegicus 2718 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 2718 R-RNO-2512800 https://reactome.org/PathwayBrowser/#/R-RNO-2512800 SCARB1:ligand is endocytosed IEA Rattus norvegicus 2718 R-RNO-264678 https://reactome.org/PathwayBrowser/#/R-RNO-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Rattus norvegicus 2718 R-RNO-264689 https://reactome.org/PathwayBrowser/#/R-RNO-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Rattus norvegicus 2718 R-RNO-264695 https://reactome.org/PathwayBrowser/#/R-RNO-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Rattus norvegicus 2718 R-RNO-265783 https://reactome.org/PathwayBrowser/#/R-RNO-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Rattus norvegicus 2718 R-RNO-266082 https://reactome.org/PathwayBrowser/#/R-RNO-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Rattus norvegicus 2718 R-RNO-266089 https://reactome.org/PathwayBrowser/#/R-RNO-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Rattus norvegicus 2718 R-RNO-266299 https://reactome.org/PathwayBrowser/#/R-RNO-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Rattus norvegicus 2718 R-RNO-266303 https://reactome.org/PathwayBrowser/#/R-RNO-266303 Spherical HDL binds C and E apolipoproteins IEA Rattus norvegicus 2718 R-RNO-266310 https://reactome.org/PathwayBrowser/#/R-RNO-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Rattus norvegicus 2718 R-RNO-266315 https://reactome.org/PathwayBrowser/#/R-RNO-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Rattus norvegicus 2718 R-RNO-349637 https://reactome.org/PathwayBrowser/#/R-RNO-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Rattus norvegicus 2718 R-RNO-349638 https://reactome.org/PathwayBrowser/#/R-RNO-349638 Disassembly of SR-BI-bound spherical HDL IEA Rattus norvegicus 2718 R-RNO-349657 https://reactome.org/PathwayBrowser/#/R-RNO-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Rattus norvegicus 2718 R-RNO-432121 https://reactome.org/PathwayBrowser/#/R-RNO-432121 LDL binds to LRP8 IEA Rattus norvegicus 2718 R-RNO-432129 https://reactome.org/PathwayBrowser/#/R-RNO-432129 FGR binds and phosphorylates LRP8 IEA Rattus norvegicus 2718 R-RNO-435244 https://reactome.org/PathwayBrowser/#/R-RNO-435244 PECAM1 is phosphorylated IEA Rattus norvegicus 2718 R-RNO-5250531 https://reactome.org/PathwayBrowser/#/R-RNO-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Rattus norvegicus 2718 R-RNO-5358340 https://reactome.org/PathwayBrowser/#/R-RNO-5358340 Autoproteolytic cleavage of Hh precursors IEA Rattus norvegicus 2718 R-RNO-6807055 https://reactome.org/PathwayBrowser/#/R-RNO-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Rattus norvegicus 2718 R-RNO-6810937 https://reactome.org/PathwayBrowser/#/R-RNO-6810937 Lamellar bodies bind the early cornified envelope IEA Rattus norvegicus 2718 R-RNO-6813720 https://reactome.org/PathwayBrowser/#/R-RNO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Rattus norvegicus 2718 R-RNO-6814387 https://reactome.org/PathwayBrowser/#/R-RNO-6814387 CASP14 cleaves filaggrin IEA Rattus norvegicus 2718 R-RNO-6814734 https://reactome.org/PathwayBrowser/#/R-RNO-6814734 CDSN binds the cornified envelope IEA Rattus norvegicus 2718 R-RNO-6814764 https://reactome.org/PathwayBrowser/#/R-RNO-6814764 Plasma membrane resorption IEA Rattus norvegicus 2718 R-RNO-8848053 https://reactome.org/PathwayBrowser/#/R-RNO-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Rattus norvegicus 2718 R-RNO-8854408 https://reactome.org/PathwayBrowser/#/R-RNO-8854408 APOBR dimer binds VLDLs IEA Rattus norvegicus 2718 R-RNO-8854462 https://reactome.org/PathwayBrowser/#/R-RNO-8854462 VLDLR binds VLDL IEA Rattus norvegicus 2718 R-RNO-8858252 https://reactome.org/PathwayBrowser/#/R-RNO-8858252 HDLBP binds HDL IEA Rattus norvegicus 2718 R-RNO-8863471 https://reactome.org/PathwayBrowser/#/R-RNO-8863471 LDLR is bound by DAB2 and ARH IEA Rattus norvegicus 2718 R-RNO-8865667 https://reactome.org/PathwayBrowser/#/R-RNO-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Rattus norvegicus 2718 R-RNO-8866304 https://reactome.org/PathwayBrowser/#/R-RNO-8866304 pre-VLDL binds lipids to form VLDL IEA Rattus norvegicus 2718 R-RNO-8866321 https://reactome.org/PathwayBrowser/#/R-RNO-8866321 VLDL binds APOC1 and APOC4 IEA Rattus norvegicus 2718 R-RNO-8866327 https://reactome.org/PathwayBrowser/#/R-RNO-8866327 VLDL translocates from SER lumen to extracellular region IEA Rattus norvegicus 2718 R-RNO-8867754 https://reactome.org/PathwayBrowser/#/R-RNO-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Rattus norvegicus 2718 R-RNO-8867756 https://reactome.org/PathwayBrowser/#/R-RNO-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Rattus norvegicus 2718 R-RNO-8868071 https://reactome.org/PathwayBrowser/#/R-RNO-8868071 Clathrin recruits PIK3C2A IEA Rattus norvegicus 2718 R-RNO-8868072 https://reactome.org/PathwayBrowser/#/R-RNO-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Rattus norvegicus 2718 R-RNO-8868236 https://reactome.org/PathwayBrowser/#/R-RNO-8868236 BAR domain proteins recruit dynamin IEA Rattus norvegicus 2718 R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 2718 R-RNO-8868651 https://reactome.org/PathwayBrowser/#/R-RNO-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Rattus norvegicus 2718 R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 2718 R-RNO-8868659 https://reactome.org/PathwayBrowser/#/R-RNO-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Rattus norvegicus 2718 R-RNO-8868660 https://reactome.org/PathwayBrowser/#/R-RNO-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Rattus norvegicus 2718 R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 2718 R-RNO-8869667 https://reactome.org/PathwayBrowser/#/R-RNO-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Rattus norvegicus 2718 R-RNO-8871193 https://reactome.org/PathwayBrowser/#/R-RNO-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Rattus norvegicus 2718 R-RNO-8871194 https://reactome.org/PathwayBrowser/#/R-RNO-8871194 RAB5 and GAPVD1 bind AP-2 IEA Rattus norvegicus 2718 R-RNO-8876366 https://reactome.org/PathwayBrowser/#/R-RNO-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Rattus norvegicus 2718 R-RNO-8876472 https://reactome.org/PathwayBrowser/#/R-RNO-8876472 NPC2 binds CHOL IEA Rattus norvegicus 2718 R-RNO-8876484 https://reactome.org/PathwayBrowser/#/R-RNO-8876484 NPC2 transfers CHOL to NPC1 IEA Rattus norvegicus 2718 R-RNO-8876485 https://reactome.org/PathwayBrowser/#/R-RNO-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Rattus norvegicus 2718 R-RNO-8876696 https://reactome.org/PathwayBrowser/#/R-RNO-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Rattus norvegicus 2718 R-RNO-8948034 https://reactome.org/PathwayBrowser/#/R-RNO-8948034 FGR binds LDL:LRP8 IEA Rattus norvegicus 2718 R-RNO-8951850 https://reactome.org/PathwayBrowser/#/R-RNO-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Rattus norvegicus 2718 R-RNO-9707586 https://reactome.org/PathwayBrowser/#/R-RNO-9707586 FeHM oxidises LDL,HDL IEA Rattus norvegicus 2718 R-SCE-1454928 https://reactome.org/PathwayBrowser/#/R-SCE-1454928 ABCG4 may mediate cholesterol efflux IEA Saccharomyces cerevisiae 2718 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 2718 R-SCE-264695 https://reactome.org/PathwayBrowser/#/R-SCE-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Saccharomyces cerevisiae 2718 R-SCE-265783 https://reactome.org/PathwayBrowser/#/R-SCE-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Saccharomyces cerevisiae 2718 R-SCE-266082 https://reactome.org/PathwayBrowser/#/R-SCE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Saccharomyces cerevisiae 2718 R-SCE-5250531 https://reactome.org/PathwayBrowser/#/R-SCE-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Saccharomyces cerevisiae 2718 R-SCE-8876472 https://reactome.org/PathwayBrowser/#/R-SCE-8876472 NPC2 binds CHOL IEA Saccharomyces cerevisiae 2718 R-SCE-8876484 https://reactome.org/PathwayBrowser/#/R-SCE-8876484 NPC2 transfers CHOL to NPC1 IEA Saccharomyces cerevisiae 2718 R-SCE-8876485 https://reactome.org/PathwayBrowser/#/R-SCE-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Saccharomyces cerevisiae 2718 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 2718 R-SPO-5250531 https://reactome.org/PathwayBrowser/#/R-SPO-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Schizosaccharomyces pombe 2718 R-SPO-6813720 https://reactome.org/PathwayBrowser/#/R-SPO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Schizosaccharomyces pombe 2718 R-SPO-8876472 https://reactome.org/PathwayBrowser/#/R-SPO-8876472 NPC2 binds CHOL IEA Schizosaccharomyces pombe 2718 R-SSC-1369028 https://reactome.org/PathwayBrowser/#/R-SSC-1369028 ABCAs mediate lipid efflux IEA Sus scrofa 2718 R-SSC-1369052 https://reactome.org/PathwayBrowser/#/R-SSC-1369052 ABCAs mediate lipid influx IEA Sus scrofa 2718 R-SSC-171059 https://reactome.org/PathwayBrowser/#/R-SSC-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] IEA Sus scrofa 2718 R-SSC-171106 https://reactome.org/PathwayBrowser/#/R-SSC-171106 LDLR:LDL complex => LDLR + LDL IEA Sus scrofa 2718 R-SSC-171122 https://reactome.org/PathwayBrowser/#/R-SSC-171122 LDL + LDLR => LDL:LDLR complex IEA Sus scrofa 2718 R-SSC-171141 https://reactome.org/PathwayBrowser/#/R-SSC-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) IEA Sus scrofa 2718 R-SSC-174587 https://reactome.org/PathwayBrowser/#/R-SSC-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] IEA Sus scrofa 2718 R-SSC-174657 https://reactome.org/PathwayBrowser/#/R-SSC-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex IEA Sus scrofa 2718 R-SSC-174660 https://reactome.org/PathwayBrowser/#/R-SSC-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron IEA Sus scrofa 2718 R-SSC-174690 https://reactome.org/PathwayBrowser/#/R-SSC-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III IEA Sus scrofa 2718 R-SSC-174706 https://reactome.org/PathwayBrowser/#/R-SSC-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) IEA Sus scrofa 2718 R-SSC-174739 https://reactome.org/PathwayBrowser/#/R-SSC-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex IEA Sus scrofa 2718 R-SSC-174741 https://reactome.org/PathwayBrowser/#/R-SSC-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron IEA Sus scrofa 2718 R-SSC-174757 https://reactome.org/PathwayBrowser/#/R-SSC-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols IEA Sus scrofa 2718 R-SSC-176609 https://reactome.org/PathwayBrowser/#/R-SSC-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Sus scrofa 2718 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 2718 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 2718 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 2718 R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 2718 R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 2718 R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 2718 R-SSC-196126 https://reactome.org/PathwayBrowser/#/R-SSC-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space IEA Sus scrofa 2718 R-SSC-196417 https://reactome.org/PathwayBrowser/#/R-SSC-196417 Reduction of desmosterol to cholesterol IEA Sus scrofa 2718 R-SSC-203130 https://reactome.org/PathwayBrowser/#/R-SSC-203130 OLR1 binds to oxidized LDL IEA Sus scrofa 2718 R-SSC-216723 https://reactome.org/PathwayBrowser/#/R-SSC-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Sus scrofa 2718 R-SSC-216756 https://reactome.org/PathwayBrowser/#/R-SSC-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa 2718 R-SSC-2168889 https://reactome.org/PathwayBrowser/#/R-SSC-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Sus scrofa 2718 R-SSC-2187332 https://reactome.org/PathwayBrowser/#/R-SSC-2187332 Cytosolic CMs translocate to extracellular region IEA Sus scrofa 2718 R-SSC-2197646 https://reactome.org/PathwayBrowser/#/R-SSC-2197646 SCARB1 (SR-BI, CLA-1) binds ligands IEA Sus scrofa 2718 R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 2718 R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 2718 R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 2718 R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 2718 R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 2718 R-SSC-2395764 https://reactome.org/PathwayBrowser/#/R-SSC-2395764 atREs binds to nascent CM IEA Sus scrofa 2718 R-SSC-2395768 https://reactome.org/PathwayBrowser/#/R-SSC-2395768 LPL hydrolyses TGs from mature CMs IEA Sus scrofa 2718 R-SSC-2395784 https://reactome.org/PathwayBrowser/#/R-SSC-2395784 Nascent CMs transform into mature CMs IEA Sus scrofa 2718 R-SSC-2404131 https://reactome.org/PathwayBrowser/#/R-SSC-2404131 LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol IEA Sus scrofa 2718 R-SSC-2423785 https://reactome.org/PathwayBrowser/#/R-SSC-2423785 CR:atREs binds apoE and HSPG IEA Sus scrofa 2718 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 2718 R-SSC-2512800 https://reactome.org/PathwayBrowser/#/R-SSC-2512800 SCARB1:ligand is endocytosed IEA Sus scrofa 2718 R-SSC-264678 https://reactome.org/PathwayBrowser/#/R-SSC-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex IEA Sus scrofa 2718 R-SSC-264689 https://reactome.org/PathwayBrowser/#/R-SSC-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL IEA Sus scrofa 2718 R-SSC-264695 https://reactome.org/PathwayBrowser/#/R-SSC-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Sus scrofa 2718 R-SSC-265783 https://reactome.org/PathwayBrowser/#/R-SSC-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Sus scrofa 2718 R-SSC-266082 https://reactome.org/PathwayBrowser/#/R-SSC-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Sus scrofa 2718 R-SSC-266089 https://reactome.org/PathwayBrowser/#/R-SSC-266089 Discoidal HDL binds membrane-associated free cholesterol IEA Sus scrofa 2718 R-SSC-266299 https://reactome.org/PathwayBrowser/#/R-SSC-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids IEA Sus scrofa 2718 R-SSC-266303 https://reactome.org/PathwayBrowser/#/R-SSC-266303 Spherical HDL binds C and E apolipoproteins IEA Sus scrofa 2718 R-SSC-266310 https://reactome.org/PathwayBrowser/#/R-SSC-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL IEA Sus scrofa 2718 R-SSC-266315 https://reactome.org/PathwayBrowser/#/R-SSC-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex IEA Sus scrofa 2718 R-SSC-349637 https://reactome.org/PathwayBrowser/#/R-SSC-349637 spherical HDL and SR-BI receptor form a complex at the cell surface IEA Sus scrofa 2718 R-SSC-349638 https://reactome.org/PathwayBrowser/#/R-SSC-349638 Disassembly of SR-BI-bound spherical HDL IEA Sus scrofa 2718 R-SSC-349657 https://reactome.org/PathwayBrowser/#/R-SSC-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle IEA Sus scrofa 2718 R-SSC-432121 https://reactome.org/PathwayBrowser/#/R-SSC-432121 LDL binds to LRP8 IEA Sus scrofa 2718 R-SSC-432129 https://reactome.org/PathwayBrowser/#/R-SSC-432129 FGR binds and phosphorylates LRP8 IEA Sus scrofa 2718 R-SSC-435244 https://reactome.org/PathwayBrowser/#/R-SSC-435244 PECAM1 is phosphorylated IEA Sus scrofa 2718 R-SSC-5250531 https://reactome.org/PathwayBrowser/#/R-SSC-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Sus scrofa 2718 R-SSC-5358340 https://reactome.org/PathwayBrowser/#/R-SSC-5358340 Autoproteolytic cleavage of Hh precursors IEA Sus scrofa 2718 R-SSC-6807055 https://reactome.org/PathwayBrowser/#/R-SSC-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Sus scrofa 2718 R-SSC-6813720 https://reactome.org/PathwayBrowser/#/R-SSC-6813720 NCEH1 hydrolyzes cholesterol esters IEA Sus scrofa 2718 R-SSC-6814764 https://reactome.org/PathwayBrowser/#/R-SSC-6814764 Plasma membrane resorption IEA Sus scrofa 2718 R-SSC-8848053 https://reactome.org/PathwayBrowser/#/R-SSC-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Sus scrofa 2718 R-SSC-8858252 https://reactome.org/PathwayBrowser/#/R-SSC-8858252 HDLBP binds HDL IEA Sus scrofa 2718 R-SSC-8863471 https://reactome.org/PathwayBrowser/#/R-SSC-8863471 LDLR is bound by DAB2 and ARH IEA Sus scrofa 2718 R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa 2718 R-SSC-8866304 https://reactome.org/PathwayBrowser/#/R-SSC-8866304 pre-VLDL binds lipids to form VLDL IEA Sus scrofa 2718 R-SSC-8866327 https://reactome.org/PathwayBrowser/#/R-SSC-8866327 VLDL translocates from SER lumen to extracellular region IEA Sus scrofa 2718 R-SSC-8867754 https://reactome.org/PathwayBrowser/#/R-SSC-8867754 F- and N- BAR domain proteins bind the clathrin-coated pit IEA Sus scrofa 2718 R-SSC-8867756 https://reactome.org/PathwayBrowser/#/R-SSC-8867756 CLASP proteins and cargo are recruited to the nascent clathrin-coated pit IEA Sus scrofa 2718 R-SSC-8868071 https://reactome.org/PathwayBrowser/#/R-SSC-8868071 Clathrin recruits PIK3C2A IEA Sus scrofa 2718 R-SSC-8868072 https://reactome.org/PathwayBrowser/#/R-SSC-8868072 Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 IEA Sus scrofa 2718 R-SSC-8868230 https://reactome.org/PathwayBrowser/#/R-SSC-8868230 SNX9 recruits components of the actin polymerizing machinery IEA Sus scrofa 2718 R-SSC-8868236 https://reactome.org/PathwayBrowser/#/R-SSC-8868236 BAR domain proteins recruit dynamin IEA Sus scrofa 2718 R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 2718 R-SSC-8868651 https://reactome.org/PathwayBrowser/#/R-SSC-8868651 Endophilins recruit synaptojanins to the clathrin-coated pit IEA Sus scrofa 2718 R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 2718 R-SSC-8868659 https://reactome.org/PathwayBrowser/#/R-SSC-8868659 Clathrin recruits auxilins to the clathrin-coated vesicle IEA Sus scrofa 2718 R-SSC-8868660 https://reactome.org/PathwayBrowser/#/R-SSC-8868660 Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle IEA Sus scrofa 2718 R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 2718 R-SSC-8869667 https://reactome.org/PathwayBrowser/#/R-SSC-8869667 oxLDL:CD36 binds TLR4:TLR6 IEA Sus scrofa 2718 R-SSC-8871193 https://reactome.org/PathwayBrowser/#/R-SSC-8871193 Dissociation of AAK1 and dephosphorylation of AP-2 mu2 IEA Sus scrofa 2718 R-SSC-8871194 https://reactome.org/PathwayBrowser/#/R-SSC-8871194 RAB5 and GAPVD1 bind AP-2 IEA Sus scrofa 2718 R-SSC-8876366 https://reactome.org/PathwayBrowser/#/R-SSC-8876366 LDL translocates from endosome lumen to lysosome lumen IEA Sus scrofa 2718 R-SSC-8876472 https://reactome.org/PathwayBrowser/#/R-SSC-8876472 NPC2 binds CHOL IEA Sus scrofa 2718 R-SSC-8876484 https://reactome.org/PathwayBrowser/#/R-SSC-8876484 NPC2 transfers CHOL to NPC1 IEA Sus scrofa 2718 R-SSC-8876485 https://reactome.org/PathwayBrowser/#/R-SSC-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Sus scrofa 2718 R-SSC-8876696 https://reactome.org/PathwayBrowser/#/R-SSC-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Sus scrofa 2718 R-SSC-8937442 https://reactome.org/PathwayBrowser/#/R-SSC-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Sus scrofa 2718 R-SSC-8948034 https://reactome.org/PathwayBrowser/#/R-SSC-8948034 FGR binds LDL:LRP8 IEA Sus scrofa 2718 R-SSC-8951850 https://reactome.org/PathwayBrowser/#/R-SSC-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane IEA Sus scrofa 2718 R-SSC-9707586 https://reactome.org/PathwayBrowser/#/R-SSC-9707586 FeHM oxidises LDL,HDL IEA Sus scrofa 2718 R-XTR-1454928 https://reactome.org/PathwayBrowser/#/R-XTR-1454928 ABCG4 may mediate cholesterol efflux IEA Xenopus tropicalis 2718 R-XTR-176609 https://reactome.org/PathwayBrowser/#/R-XTR-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Xenopus tropicalis 2718 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 2718 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 2718 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 2718 R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 2718 R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 2718 R-XTR-196126 https://reactome.org/PathwayBrowser/#/R-XTR-196126 STAR mediates CHOL translocation from cytosol to mitochondrial intermembrane space IEA Xenopus tropicalis 2718 R-XTR-196417 https://reactome.org/PathwayBrowser/#/R-XTR-196417 Reduction of desmosterol to cholesterol IEA Xenopus tropicalis 2718 R-XTR-264695 https://reactome.org/PathwayBrowser/#/R-XTR-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) IEA Xenopus tropicalis 2718 R-XTR-266082 https://reactome.org/PathwayBrowser/#/R-XTR-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Xenopus tropicalis 2718 R-XTR-5250531 https://reactome.org/PathwayBrowser/#/R-XTR-5250531 ARV1 transports CHOL from ER membrane to plasma membrane IEA Xenopus tropicalis 2718 R-XTR-5358340 https://reactome.org/PathwayBrowser/#/R-XTR-5358340 Autoproteolytic cleavage of Hh precursors IEA Xenopus tropicalis 2718 R-XTR-6807055 https://reactome.org/PathwayBrowser/#/R-XTR-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Xenopus tropicalis 2718 R-XTR-8848053 https://reactome.org/PathwayBrowser/#/R-XTR-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Xenopus tropicalis 2718 R-XTR-8876472 https://reactome.org/PathwayBrowser/#/R-XTR-8876472 NPC2 binds CHOL IEA Xenopus tropicalis 2718 R-XTR-8876484 https://reactome.org/PathwayBrowser/#/R-XTR-8876484 NPC2 transfers CHOL to NPC1 IEA Xenopus tropicalis 2718 R-XTR-8876485 https://reactome.org/PathwayBrowser/#/R-XTR-8876485 CHOL translocates from lysosome membrane to ER membrane IEA Xenopus tropicalis 2718 R-XTR-8876696 https://reactome.org/PathwayBrowser/#/R-XTR-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST IEA Xenopus tropicalis 2739 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 2739 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 2739 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 2739 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 2739 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 2739 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 2739 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 2739 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 2739 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 2739 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 2739 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 2739 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 2739 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 2739 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 2746 R-BTA-191366 https://reactome.org/PathwayBrowser/#/R-BTA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Bos taurus 2746 R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 2746 R-BTA-9755937 https://reactome.org/PathwayBrowser/#/R-BTA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Bos taurus 2746 R-CEL-9755937 https://reactome.org/PathwayBrowser/#/R-CEL-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Caenorhabditis elegans 2746 R-CFA-191366 https://reactome.org/PathwayBrowser/#/R-CFA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Canis familiaris 2746 R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 2746 R-CFA-9755937 https://reactome.org/PathwayBrowser/#/R-CFA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Canis familiaris 2746 R-DDI-191366 https://reactome.org/PathwayBrowser/#/R-DDI-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Dictyostelium discoideum 2746 R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 2746 R-DRE-191366 https://reactome.org/PathwayBrowser/#/R-DRE-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Danio rerio 2746 R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 2746 R-DRE-9755937 https://reactome.org/PathwayBrowser/#/R-DRE-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Danio rerio 2746 R-GGA-191366 https://reactome.org/PathwayBrowser/#/R-GGA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Gallus gallus 2746 R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 2746 R-GGA-9755937 https://reactome.org/PathwayBrowser/#/R-GGA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Gallus gallus 2746 R-HSA-191366 https://reactome.org/PathwayBrowser/#/R-HSA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol TAS Homo sapiens 2746 R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 2746 R-HSA-9755937 https://reactome.org/PathwayBrowser/#/R-HSA-9755937 DHCR24 reduces LAN to 24,25-dhLAN TAS Homo sapiens 2746 R-MMU-191366 https://reactome.org/PathwayBrowser/#/R-MMU-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Mus musculus 2746 R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 2746 R-MMU-9755937 https://reactome.org/PathwayBrowser/#/R-MMU-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Mus musculus 2746 R-RNO-191366 https://reactome.org/PathwayBrowser/#/R-RNO-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Rattus norvegicus 2746 R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 2746 R-RNO-9755937 https://reactome.org/PathwayBrowser/#/R-RNO-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Rattus norvegicus 2746 R-SCE-191366 https://reactome.org/PathwayBrowser/#/R-SCE-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Saccharomyces cerevisiae 2746 R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 2746 R-SPO-191366 https://reactome.org/PathwayBrowser/#/R-SPO-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Schizosaccharomyces pombe 2746 R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 2746 R-SSC-191366 https://reactome.org/PathwayBrowser/#/R-SSC-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Sus scrofa 2746 R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 2746 R-SSC-9755937 https://reactome.org/PathwayBrowser/#/R-SSC-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Sus scrofa 2746 R-XTR-191366 https://reactome.org/PathwayBrowser/#/R-XTR-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Xenopus tropicalis 2746 R-XTR-9755937 https://reactome.org/PathwayBrowser/#/R-XTR-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Xenopus tropicalis 2748 R-BTA-196402 https://reactome.org/PathwayBrowser/#/R-BTA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Bos taurus 2748 R-BTA-196417 https://reactome.org/PathwayBrowser/#/R-BTA-196417 Reduction of desmosterol to cholesterol IEA Bos taurus 2748 R-CEL-196402 https://reactome.org/PathwayBrowser/#/R-CEL-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Caenorhabditis elegans 2748 R-CEL-196417 https://reactome.org/PathwayBrowser/#/R-CEL-196417 Reduction of desmosterol to cholesterol IEA Caenorhabditis elegans 2748 R-CFA-196402 https://reactome.org/PathwayBrowser/#/R-CFA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Canis familiaris 2748 R-CFA-196417 https://reactome.org/PathwayBrowser/#/R-CFA-196417 Reduction of desmosterol to cholesterol IEA Canis familiaris 2748 R-DRE-196402 https://reactome.org/PathwayBrowser/#/R-DRE-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Danio rerio 2748 R-DRE-196417 https://reactome.org/PathwayBrowser/#/R-DRE-196417 Reduction of desmosterol to cholesterol IEA Danio rerio 2748 R-GGA-196402 https://reactome.org/PathwayBrowser/#/R-GGA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Gallus gallus 2748 R-GGA-196417 https://reactome.org/PathwayBrowser/#/R-GGA-196417 Reduction of desmosterol to cholesterol IEA Gallus gallus 2748 R-HSA-196402 https://reactome.org/PathwayBrowser/#/R-HSA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol TAS Homo sapiens 2748 R-HSA-196417 https://reactome.org/PathwayBrowser/#/R-HSA-196417 Reduction of desmosterol to cholesterol TAS Homo sapiens 2748 R-MMU-196402 https://reactome.org/PathwayBrowser/#/R-MMU-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Mus musculus 2748 R-MMU-196417 https://reactome.org/PathwayBrowser/#/R-MMU-196417 Reduction of desmosterol to cholesterol IEA Mus musculus 2748 R-RNO-196402 https://reactome.org/PathwayBrowser/#/R-RNO-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Rattus norvegicus 2748 R-RNO-196417 https://reactome.org/PathwayBrowser/#/R-RNO-196417 Reduction of desmosterol to cholesterol IEA Rattus norvegicus 2748 R-SSC-196402 https://reactome.org/PathwayBrowser/#/R-SSC-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Sus scrofa 2748 R-SSC-196417 https://reactome.org/PathwayBrowser/#/R-SSC-196417 Reduction of desmosterol to cholesterol IEA Sus scrofa 2748 R-XTR-196402 https://reactome.org/PathwayBrowser/#/R-XTR-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Xenopus tropicalis 2748 R-XTR-196417 https://reactome.org/PathwayBrowser/#/R-XTR-196417 Reduction of desmosterol to cholesterol IEA Xenopus tropicalis 2750 R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 2750 R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 2750 R-BTA-4720432 https://reactome.org/PathwayBrowser/#/R-BTA-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Bos taurus 2750 R-BTA-4720446 https://reactome.org/PathwayBrowser/#/R-BTA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Bos taurus 2750 R-BTA-9024326 https://reactome.org/PathwayBrowser/#/R-BTA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Bos taurus 2750 R-BTA-9024334 https://reactome.org/PathwayBrowser/#/R-BTA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Bos taurus 2750 R-BTA-9029517 https://reactome.org/PathwayBrowser/#/R-BTA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Bos taurus 2750 R-BTA-9029551 https://reactome.org/PathwayBrowser/#/R-BTA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Bos taurus 2750 R-BTA-9029561 https://reactome.org/PathwayBrowser/#/R-BTA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Bos taurus 2750 R-BTA-9029566 https://reactome.org/PathwayBrowser/#/R-BTA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Bos taurus 2750 R-BTA-9029580 https://reactome.org/PathwayBrowser/#/R-BTA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Bos taurus 2750 R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 2750 R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 2750 R-CFA-9024326 https://reactome.org/PathwayBrowser/#/R-CFA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Canis familiaris 2750 R-CFA-9024334 https://reactome.org/PathwayBrowser/#/R-CFA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Canis familiaris 2750 R-CFA-9029517 https://reactome.org/PathwayBrowser/#/R-CFA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Canis familiaris 2750 R-CFA-9029551 https://reactome.org/PathwayBrowser/#/R-CFA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Canis familiaris 2750 R-CFA-9029561 https://reactome.org/PathwayBrowser/#/R-CFA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Canis familiaris 2750 R-CFA-9029566 https://reactome.org/PathwayBrowser/#/R-CFA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Canis familiaris 2750 R-CFA-9029580 https://reactome.org/PathwayBrowser/#/R-CFA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Canis familiaris 2750 R-DME-4720432 https://reactome.org/PathwayBrowser/#/R-DME-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Drosophila melanogaster 2750 R-DME-4720446 https://reactome.org/PathwayBrowser/#/R-DME-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Drosophila melanogaster 2750 R-DME-9024326 https://reactome.org/PathwayBrowser/#/R-DME-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Drosophila melanogaster 2750 R-DME-9024334 https://reactome.org/PathwayBrowser/#/R-DME-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Drosophila melanogaster 2750 R-DME-9029517 https://reactome.org/PathwayBrowser/#/R-DME-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Drosophila melanogaster 2750 R-DME-9029551 https://reactome.org/PathwayBrowser/#/R-DME-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Drosophila melanogaster 2750 R-DME-9029561 https://reactome.org/PathwayBrowser/#/R-DME-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Drosophila melanogaster 2750 R-DME-9029566 https://reactome.org/PathwayBrowser/#/R-DME-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Drosophila melanogaster 2750 R-DME-9029580 https://reactome.org/PathwayBrowser/#/R-DME-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Drosophila melanogaster 2750 R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 2750 R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 2750 R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 2750 R-GGA-4720446 https://reactome.org/PathwayBrowser/#/R-GGA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Gallus gallus 2750 R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 2750 R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 2750 R-HSA-193767 https://reactome.org/PathwayBrowser/#/R-HSA-193767 Influx of 24-hydroxycholesterol TAS Homo sapiens 2750 R-HSA-193776 https://reactome.org/PathwayBrowser/#/R-HSA-193776 Efflux of 24-hydroxycholesterol TAS Homo sapiens 2750 R-HSA-4720432 https://reactome.org/PathwayBrowser/#/R-HSA-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 TAS Homo sapiens 2750 R-HSA-4720446 https://reactome.org/PathwayBrowser/#/R-HSA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 TAS Homo sapiens 2750 R-HSA-9024326 https://reactome.org/PathwayBrowser/#/R-HSA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex TAS Homo sapiens 2750 R-HSA-9024334 https://reactome.org/PathwayBrowser/#/R-HSA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene TAS Homo sapiens 2750 R-HSA-9024361 https://reactome.org/PathwayBrowser/#/R-HSA-9024361 Expression of ABCG1 regulated by NR1H2,3 TAS Homo sapiens 2750 R-HSA-9024386 https://reactome.org/PathwayBrowser/#/R-HSA-9024386 Oxysterol-induced binding of NR1H2,3:RXR to the ABCG1 gene TAS Homo sapiens 2750 R-HSA-9028524 https://reactome.org/PathwayBrowser/#/R-HSA-9028524 NR1H3, NRIP1 bind the PCK1 gene TAS Homo sapiens 2750 R-HSA-9028525 https://reactome.org/PathwayBrowser/#/R-HSA-9028525 NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene TAS Homo sapiens 2750 R-HSA-9028526 https://reactome.org/PathwayBrowser/#/R-HSA-9028526 NR1H2 or NR1H3, NRIP1 bind the SCD gene TAS Homo sapiens 2750 R-HSA-9028533 https://reactome.org/PathwayBrowser/#/R-HSA-9028533 NR1H2,3, NRIP1 bind the FASN gene TAS Homo sapiens 2750 R-HSA-9029517 https://reactome.org/PathwayBrowser/#/R-HSA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex TAS Homo sapiens 2750 R-HSA-9029521 https://reactome.org/PathwayBrowser/#/R-HSA-9029521 NR1H2,3 binds the ABCG5 gene TAS Homo sapiens 2750 R-HSA-9029531 https://reactome.org/PathwayBrowser/#/R-HSA-9029531 Expression of ABCG5 regulated by NR1H2,3 TAS Homo sapiens 2750 R-HSA-9029536 https://reactome.org/PathwayBrowser/#/R-HSA-9029536 Expression of UGT1A3 TAS Homo sapiens 2750 R-HSA-9029551 https://reactome.org/PathwayBrowser/#/R-HSA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex TAS Homo sapiens 2750 R-HSA-9029555 https://reactome.org/PathwayBrowser/#/R-HSA-9029555 NR1H2,3 binds the ABCG8 gene TAS Homo sapiens 2750 R-HSA-9029561 https://reactome.org/PathwayBrowser/#/R-HSA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter TAS Homo sapiens 2750 R-HSA-9029566 https://reactome.org/PathwayBrowser/#/R-HSA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene TAS Homo sapiens 2750 R-HSA-9029580 https://reactome.org/PathwayBrowser/#/R-HSA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex TAS Homo sapiens 2750 R-HSA-9029591 https://reactome.org/PathwayBrowser/#/R-HSA-9029591 Expression of ABCG8 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9031510 https://reactome.org/PathwayBrowser/#/R-HSA-9031510 Expression of APOC1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9031512 https://reactome.org/PathwayBrowser/#/R-HSA-9031512 Expression of APOE regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9031518 https://reactome.org/PathwayBrowser/#/R-HSA-9031518 NR1H2,3 binds the APOC1 gene TAS Homo sapiens 2750 R-HSA-9031521 https://reactome.org/PathwayBrowser/#/R-HSA-9031521 NR1H2,3 binds the APOC2 gene TAS Homo sapiens 2750 R-HSA-9031522 https://reactome.org/PathwayBrowser/#/R-HSA-9031522 NR1H2,3 binds the APOE gene TAS Homo sapiens 2750 R-HSA-9031527 https://reactome.org/PathwayBrowser/#/R-HSA-9031527 Expression of APOC2 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9035133 https://reactome.org/PathwayBrowser/#/R-HSA-9035133 NR1H2,3 binds the CETP gene TAS Homo sapiens 2750 R-HSA-9035143 https://reactome.org/PathwayBrowser/#/R-HSA-9035143 NR1H2,3 binds the APOC4 gene TAS Homo sapiens 2750 R-HSA-9035167 https://reactome.org/PathwayBrowser/#/R-HSA-9035167 NR1H2,3 binds the EEPD1 gene TAS Homo sapiens 2750 R-HSA-9035169 https://reactome.org/PathwayBrowser/#/R-HSA-9035169 Expression of CETP regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9035180 https://reactome.org/PathwayBrowser/#/R-HSA-9035180 Expression of EEPD1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9035185 https://reactome.org/PathwayBrowser/#/R-HSA-9035185 NR1H2,3 binds the NR1H3 gene TAS Homo sapiens 2750 R-HSA-9035279 https://reactome.org/PathwayBrowser/#/R-HSA-9035279 Expression of APOC4 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9035281 https://reactome.org/PathwayBrowser/#/R-HSA-9035281 NR1H3 gene transcription regulated by NR1H2,3 TAS Homo sapiens 2750 R-HSA-9605051 https://reactome.org/PathwayBrowser/#/R-HSA-9605051 Expression of PCK1 regulated by NR1H3 TAS Homo sapiens 2750 R-HSA-9605056 https://reactome.org/PathwayBrowser/#/R-HSA-9605056 Expression of SREBF1 (SREBP1) regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9605057 https://reactome.org/PathwayBrowser/#/R-HSA-9605057 ABCA1 gene transcription regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9605060 https://reactome.org/PathwayBrowser/#/R-HSA-9605060 Expression of SCD regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9605063 https://reactome.org/PathwayBrowser/#/R-HSA-9605063 Expression of FASN regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9607342 https://reactome.org/PathwayBrowser/#/R-HSA-9607342 Expression of FABP6 regulated by NR1H2,3 TAS Homo sapiens 2750 R-HSA-9608039 https://reactome.org/PathwayBrowser/#/R-HSA-9608039 NR1H2,3 binds the PLIN1 gene TAS Homo sapiens 2750 R-HSA-9608048 https://reactome.org/PathwayBrowser/#/R-HSA-9608048 Expression of PLIN1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9618394 https://reactome.org/PathwayBrowser/#/R-HSA-9618394 ARL4C gene transcription regulated by NR1H2,3 TAS Homo sapiens 2750 R-HSA-9618407 https://reactome.org/PathwayBrowser/#/R-HSA-9618407 NR1H2,3 binds the ARL4C gene TAS Homo sapiens 2750 R-HSA-9623365 https://reactome.org/PathwayBrowser/#/R-HSA-9623365 Expression of MYLIP regulated by NR1H2,3 TAS Homo sapiens 2750 R-HSA-9623366 https://reactome.org/PathwayBrowser/#/R-HSA-9623366 NR1H2,3 binds the MYLIP gene TAS Homo sapiens 2750 R-HSA-9624353 https://reactome.org/PathwayBrowser/#/R-HSA-9624353 NR1H2,3 binds the PLTP gene TAS Homo sapiens 2750 R-HSA-9624365 https://reactome.org/PathwayBrowser/#/R-HSA-9624365 Expression of PLTP regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9631296 https://reactome.org/PathwayBrowser/#/R-HSA-9631296 NR1H2,3 binds the FABP6 gene TAS Homo sapiens 2750 R-HSA-9657767 https://reactome.org/PathwayBrowser/#/R-HSA-9657767 Expression of APOD regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9657775 https://reactome.org/PathwayBrowser/#/R-HSA-9657775 Expression of ANGPTL3 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2750 R-HSA-9657786 https://reactome.org/PathwayBrowser/#/R-HSA-9657786 NR1H2,3 binds the APOD gene TAS Homo sapiens 2750 R-HSA-9657836 https://reactome.org/PathwayBrowser/#/R-HSA-9657836 NR1H2,3 binds the ANGPTL3 gene TAS Homo sapiens 2750 R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 2750 R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 2750 R-MMU-4720432 https://reactome.org/PathwayBrowser/#/R-MMU-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Mus musculus 2750 R-MMU-4720446 https://reactome.org/PathwayBrowser/#/R-MMU-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Mus musculus 2750 R-MMU-9024326 https://reactome.org/PathwayBrowser/#/R-MMU-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Mus musculus 2750 R-MMU-9024334 https://reactome.org/PathwayBrowser/#/R-MMU-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Mus musculus 2750 R-MMU-9029517 https://reactome.org/PathwayBrowser/#/R-MMU-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Mus musculus 2750 R-MMU-9029551 https://reactome.org/PathwayBrowser/#/R-MMU-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Mus musculus 2750 R-MMU-9029561 https://reactome.org/PathwayBrowser/#/R-MMU-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Mus musculus 2750 R-MMU-9029566 https://reactome.org/PathwayBrowser/#/R-MMU-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Mus musculus 2750 R-MMU-9029580 https://reactome.org/PathwayBrowser/#/R-MMU-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Mus musculus 2750 R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 2750 R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 2750 R-RNO-4720432 https://reactome.org/PathwayBrowser/#/R-RNO-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Rattus norvegicus 2750 R-RNO-4720446 https://reactome.org/PathwayBrowser/#/R-RNO-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Rattus norvegicus 2750 R-RNO-9024326 https://reactome.org/PathwayBrowser/#/R-RNO-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Rattus norvegicus 2750 R-RNO-9024334 https://reactome.org/PathwayBrowser/#/R-RNO-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Rattus norvegicus 2750 R-RNO-9029517 https://reactome.org/PathwayBrowser/#/R-RNO-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Rattus norvegicus 2750 R-RNO-9029551 https://reactome.org/PathwayBrowser/#/R-RNO-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Rattus norvegicus 2750 R-RNO-9029561 https://reactome.org/PathwayBrowser/#/R-RNO-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Rattus norvegicus 2750 R-RNO-9029566 https://reactome.org/PathwayBrowser/#/R-RNO-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Rattus norvegicus 2750 R-RNO-9029580 https://reactome.org/PathwayBrowser/#/R-RNO-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Rattus norvegicus 2750 R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 2750 R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 2750 R-SSC-4720432 https://reactome.org/PathwayBrowser/#/R-SSC-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Sus scrofa 2750 R-SSC-4720446 https://reactome.org/PathwayBrowser/#/R-SSC-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Sus scrofa 2750 R-SSC-9024326 https://reactome.org/PathwayBrowser/#/R-SSC-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Sus scrofa 2750 R-SSC-9024334 https://reactome.org/PathwayBrowser/#/R-SSC-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Sus scrofa 2750 R-SSC-9029517 https://reactome.org/PathwayBrowser/#/R-SSC-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Sus scrofa 2750 R-SSC-9029551 https://reactome.org/PathwayBrowser/#/R-SSC-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Sus scrofa 2750 R-SSC-9029561 https://reactome.org/PathwayBrowser/#/R-SSC-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Sus scrofa 2750 R-SSC-9029566 https://reactome.org/PathwayBrowser/#/R-SSC-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Sus scrofa 2750 R-SSC-9029580 https://reactome.org/PathwayBrowser/#/R-SSC-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Sus scrofa 2750 R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 2750 R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 2750 R-XTR-9024326 https://reactome.org/PathwayBrowser/#/R-XTR-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Xenopus tropicalis 2750 R-XTR-9024334 https://reactome.org/PathwayBrowser/#/R-XTR-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Xenopus tropicalis 2750 R-XTR-9029517 https://reactome.org/PathwayBrowser/#/R-XTR-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Xenopus tropicalis 2750 R-XTR-9029566 https://reactome.org/PathwayBrowser/#/R-XTR-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Xenopus tropicalis 2752 R-BTA-9024326 https://reactome.org/PathwayBrowser/#/R-BTA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Bos taurus 2752 R-BTA-9024334 https://reactome.org/PathwayBrowser/#/R-BTA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Bos taurus 2752 R-BTA-9029517 https://reactome.org/PathwayBrowser/#/R-BTA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Bos taurus 2752 R-BTA-9029551 https://reactome.org/PathwayBrowser/#/R-BTA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Bos taurus 2752 R-BTA-9029561 https://reactome.org/PathwayBrowser/#/R-BTA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Bos taurus 2752 R-BTA-9029566 https://reactome.org/PathwayBrowser/#/R-BTA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Bos taurus 2752 R-BTA-9029580 https://reactome.org/PathwayBrowser/#/R-BTA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Bos taurus 2752 R-BTA-9038029 https://reactome.org/PathwayBrowser/#/R-BTA-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Bos taurus 2752 R-CFA-9024326 https://reactome.org/PathwayBrowser/#/R-CFA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Canis familiaris 2752 R-CFA-9024334 https://reactome.org/PathwayBrowser/#/R-CFA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Canis familiaris 2752 R-CFA-9029517 https://reactome.org/PathwayBrowser/#/R-CFA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Canis familiaris 2752 R-CFA-9029551 https://reactome.org/PathwayBrowser/#/R-CFA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Canis familiaris 2752 R-CFA-9029561 https://reactome.org/PathwayBrowser/#/R-CFA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Canis familiaris 2752 R-CFA-9029566 https://reactome.org/PathwayBrowser/#/R-CFA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Canis familiaris 2752 R-CFA-9029580 https://reactome.org/PathwayBrowser/#/R-CFA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Canis familiaris 2752 R-CFA-9038029 https://reactome.org/PathwayBrowser/#/R-CFA-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Canis familiaris 2752 R-DME-9024326 https://reactome.org/PathwayBrowser/#/R-DME-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Drosophila melanogaster 2752 R-DME-9024334 https://reactome.org/PathwayBrowser/#/R-DME-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Drosophila melanogaster 2752 R-DME-9029517 https://reactome.org/PathwayBrowser/#/R-DME-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Drosophila melanogaster 2752 R-DME-9029551 https://reactome.org/PathwayBrowser/#/R-DME-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Drosophila melanogaster 2752 R-DME-9029561 https://reactome.org/PathwayBrowser/#/R-DME-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Drosophila melanogaster 2752 R-DME-9029566 https://reactome.org/PathwayBrowser/#/R-DME-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Drosophila melanogaster 2752 R-DME-9029580 https://reactome.org/PathwayBrowser/#/R-DME-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Drosophila melanogaster 2752 R-DME-9038029 https://reactome.org/PathwayBrowser/#/R-DME-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Drosophila melanogaster 2752 R-DRE-9038029 https://reactome.org/PathwayBrowser/#/R-DRE-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Danio rerio 2752 R-GGA-9038029 https://reactome.org/PathwayBrowser/#/R-GGA-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Gallus gallus 2752 R-HSA-9024326 https://reactome.org/PathwayBrowser/#/R-HSA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex TAS Homo sapiens 2752 R-HSA-9024334 https://reactome.org/PathwayBrowser/#/R-HSA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene TAS Homo sapiens 2752 R-HSA-9024361 https://reactome.org/PathwayBrowser/#/R-HSA-9024361 Expression of ABCG1 regulated by NR1H2,3 TAS Homo sapiens 2752 R-HSA-9024386 https://reactome.org/PathwayBrowser/#/R-HSA-9024386 Oxysterol-induced binding of NR1H2,3:RXR to the ABCG1 gene TAS Homo sapiens 2752 R-HSA-9028524 https://reactome.org/PathwayBrowser/#/R-HSA-9028524 NR1H3, NRIP1 bind the PCK1 gene TAS Homo sapiens 2752 R-HSA-9028525 https://reactome.org/PathwayBrowser/#/R-HSA-9028525 NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene TAS Homo sapiens 2752 R-HSA-9028526 https://reactome.org/PathwayBrowser/#/R-HSA-9028526 NR1H2 or NR1H3, NRIP1 bind the SCD gene TAS Homo sapiens 2752 R-HSA-9028533 https://reactome.org/PathwayBrowser/#/R-HSA-9028533 NR1H2,3, NRIP1 bind the FASN gene TAS Homo sapiens 2752 R-HSA-9029517 https://reactome.org/PathwayBrowser/#/R-HSA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex TAS Homo sapiens 2752 R-HSA-9029521 https://reactome.org/PathwayBrowser/#/R-HSA-9029521 NR1H2,3 binds the ABCG5 gene TAS Homo sapiens 2752 R-HSA-9029531 https://reactome.org/PathwayBrowser/#/R-HSA-9029531 Expression of ABCG5 regulated by NR1H2,3 TAS Homo sapiens 2752 R-HSA-9029536 https://reactome.org/PathwayBrowser/#/R-HSA-9029536 Expression of UGT1A3 TAS Homo sapiens 2752 R-HSA-9029551 https://reactome.org/PathwayBrowser/#/R-HSA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex TAS Homo sapiens 2752 R-HSA-9029555 https://reactome.org/PathwayBrowser/#/R-HSA-9029555 NR1H2,3 binds the ABCG8 gene TAS Homo sapiens 2752 R-HSA-9029561 https://reactome.org/PathwayBrowser/#/R-HSA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter TAS Homo sapiens 2752 R-HSA-9029566 https://reactome.org/PathwayBrowser/#/R-HSA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene TAS Homo sapiens 2752 R-HSA-9029580 https://reactome.org/PathwayBrowser/#/R-HSA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex TAS Homo sapiens 2752 R-HSA-9029591 https://reactome.org/PathwayBrowser/#/R-HSA-9029591 Expression of ABCG8 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9031510 https://reactome.org/PathwayBrowser/#/R-HSA-9031510 Expression of APOC1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9031512 https://reactome.org/PathwayBrowser/#/R-HSA-9031512 Expression of APOE regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9031518 https://reactome.org/PathwayBrowser/#/R-HSA-9031518 NR1H2,3 binds the APOC1 gene TAS Homo sapiens 2752 R-HSA-9031521 https://reactome.org/PathwayBrowser/#/R-HSA-9031521 NR1H2,3 binds the APOC2 gene TAS Homo sapiens 2752 R-HSA-9031522 https://reactome.org/PathwayBrowser/#/R-HSA-9031522 NR1H2,3 binds the APOE gene TAS Homo sapiens 2752 R-HSA-9031527 https://reactome.org/PathwayBrowser/#/R-HSA-9031527 Expression of APOC2 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9035133 https://reactome.org/PathwayBrowser/#/R-HSA-9035133 NR1H2,3 binds the CETP gene TAS Homo sapiens 2752 R-HSA-9035143 https://reactome.org/PathwayBrowser/#/R-HSA-9035143 NR1H2,3 binds the APOC4 gene TAS Homo sapiens 2752 R-HSA-9035167 https://reactome.org/PathwayBrowser/#/R-HSA-9035167 NR1H2,3 binds the EEPD1 gene TAS Homo sapiens 2752 R-HSA-9035169 https://reactome.org/PathwayBrowser/#/R-HSA-9035169 Expression of CETP regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9035180 https://reactome.org/PathwayBrowser/#/R-HSA-9035180 Expression of EEPD1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9035185 https://reactome.org/PathwayBrowser/#/R-HSA-9035185 NR1H2,3 binds the NR1H3 gene TAS Homo sapiens 2752 R-HSA-9035279 https://reactome.org/PathwayBrowser/#/R-HSA-9035279 Expression of APOC4 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9035281 https://reactome.org/PathwayBrowser/#/R-HSA-9035281 NR1H3 gene transcription regulated by NR1H2,3 TAS Homo sapiens 2752 R-HSA-9038029 https://reactome.org/PathwayBrowser/#/R-HSA-9038029 27-hydroxysterol binds ESR1, ESR2 TAS Homo sapiens 2752 R-HSA-9605051 https://reactome.org/PathwayBrowser/#/R-HSA-9605051 Expression of PCK1 regulated by NR1H3 TAS Homo sapiens 2752 R-HSA-9605056 https://reactome.org/PathwayBrowser/#/R-HSA-9605056 Expression of SREBF1 (SREBP1) regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9605057 https://reactome.org/PathwayBrowser/#/R-HSA-9605057 ABCA1 gene transcription regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9605060 https://reactome.org/PathwayBrowser/#/R-HSA-9605060 Expression of SCD regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9605063 https://reactome.org/PathwayBrowser/#/R-HSA-9605063 Expression of FASN regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9607342 https://reactome.org/PathwayBrowser/#/R-HSA-9607342 Expression of FABP6 regulated by NR1H2,3 TAS Homo sapiens 2752 R-HSA-9608039 https://reactome.org/PathwayBrowser/#/R-HSA-9608039 NR1H2,3 binds the PLIN1 gene TAS Homo sapiens 2752 R-HSA-9608048 https://reactome.org/PathwayBrowser/#/R-HSA-9608048 Expression of PLIN1 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9618394 https://reactome.org/PathwayBrowser/#/R-HSA-9618394 ARL4C gene transcription regulated by NR1H2,3 TAS Homo sapiens 2752 R-HSA-9618407 https://reactome.org/PathwayBrowser/#/R-HSA-9618407 NR1H2,3 binds the ARL4C gene TAS Homo sapiens 2752 R-HSA-9623365 https://reactome.org/PathwayBrowser/#/R-HSA-9623365 Expression of MYLIP regulated by NR1H2,3 TAS Homo sapiens 2752 R-HSA-9623366 https://reactome.org/PathwayBrowser/#/R-HSA-9623366 NR1H2,3 binds the MYLIP gene TAS Homo sapiens 2752 R-HSA-9624353 https://reactome.org/PathwayBrowser/#/R-HSA-9624353 NR1H2,3 binds the PLTP gene TAS Homo sapiens 2752 R-HSA-9624365 https://reactome.org/PathwayBrowser/#/R-HSA-9624365 Expression of PLTP regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9631296 https://reactome.org/PathwayBrowser/#/R-HSA-9631296 NR1H2,3 binds the FABP6 gene TAS Homo sapiens 2752 R-HSA-9657767 https://reactome.org/PathwayBrowser/#/R-HSA-9657767 Expression of APOD regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9657775 https://reactome.org/PathwayBrowser/#/R-HSA-9657775 Expression of ANGPTL3 regulated by NR1H2 or NR1H3 TAS Homo sapiens 2752 R-HSA-9657786 https://reactome.org/PathwayBrowser/#/R-HSA-9657786 NR1H2,3 binds the APOD gene TAS Homo sapiens 2752 R-HSA-9657836 https://reactome.org/PathwayBrowser/#/R-HSA-9657836 NR1H2,3 binds the ANGPTL3 gene TAS Homo sapiens 2752 R-MMU-9024326 https://reactome.org/PathwayBrowser/#/R-MMU-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Mus musculus 2752 R-MMU-9024334 https://reactome.org/PathwayBrowser/#/R-MMU-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Mus musculus 2752 R-MMU-9029517 https://reactome.org/PathwayBrowser/#/R-MMU-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Mus musculus 2752 R-MMU-9029551 https://reactome.org/PathwayBrowser/#/R-MMU-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Mus musculus 2752 R-MMU-9029561 https://reactome.org/PathwayBrowser/#/R-MMU-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Mus musculus 2752 R-MMU-9029566 https://reactome.org/PathwayBrowser/#/R-MMU-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Mus musculus 2752 R-MMU-9029580 https://reactome.org/PathwayBrowser/#/R-MMU-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Mus musculus 2752 R-MMU-9038029 https://reactome.org/PathwayBrowser/#/R-MMU-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Mus musculus 2752 R-RNO-9024326 https://reactome.org/PathwayBrowser/#/R-RNO-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Rattus norvegicus 2752 R-RNO-9024334 https://reactome.org/PathwayBrowser/#/R-RNO-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Rattus norvegicus 2752 R-RNO-9029517 https://reactome.org/PathwayBrowser/#/R-RNO-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Rattus norvegicus 2752 R-RNO-9029551 https://reactome.org/PathwayBrowser/#/R-RNO-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Rattus norvegicus 2752 R-RNO-9029561 https://reactome.org/PathwayBrowser/#/R-RNO-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Rattus norvegicus 2752 R-RNO-9029566 https://reactome.org/PathwayBrowser/#/R-RNO-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Rattus norvegicus 2752 R-RNO-9029580 https://reactome.org/PathwayBrowser/#/R-RNO-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Rattus norvegicus 2752 R-RNO-9038029 https://reactome.org/PathwayBrowser/#/R-RNO-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Rattus norvegicus 2752 R-SSC-9024326 https://reactome.org/PathwayBrowser/#/R-SSC-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Sus scrofa 2752 R-SSC-9024334 https://reactome.org/PathwayBrowser/#/R-SSC-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Sus scrofa 2752 R-SSC-9029517 https://reactome.org/PathwayBrowser/#/R-SSC-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Sus scrofa 2752 R-SSC-9029551 https://reactome.org/PathwayBrowser/#/R-SSC-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex IEA Sus scrofa 2752 R-SSC-9029561 https://reactome.org/PathwayBrowser/#/R-SSC-9029561 NCOA1 recruits EP300 to the ABCA1 promoter IEA Sus scrofa 2752 R-SSC-9029566 https://reactome.org/PathwayBrowser/#/R-SSC-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Sus scrofa 2752 R-SSC-9029580 https://reactome.org/PathwayBrowser/#/R-SSC-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex IEA Sus scrofa 2752 R-SSC-9038029 https://reactome.org/PathwayBrowser/#/R-SSC-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Sus scrofa 2752 R-XTR-9024326 https://reactome.org/PathwayBrowser/#/R-XTR-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex IEA Xenopus tropicalis 2752 R-XTR-9024334 https://reactome.org/PathwayBrowser/#/R-XTR-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene IEA Xenopus tropicalis 2752 R-XTR-9029517 https://reactome.org/PathwayBrowser/#/R-XTR-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex IEA Xenopus tropicalis 2752 R-XTR-9029566 https://reactome.org/PathwayBrowser/#/R-XTR-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene IEA Xenopus tropicalis 2752 R-XTR-9038029 https://reactome.org/PathwayBrowser/#/R-XTR-9038029 27-hydroxysterol binds ESR1, ESR2 IEA Xenopus tropicalis 2765 R-BTA-4755524 https://reactome.org/PathwayBrowser/#/R-BTA-4755524 SUMOylation of NR1I2 with SUMO3 IEA Bos taurus 2765 R-DME-4755524 https://reactome.org/PathwayBrowser/#/R-DME-4755524 SUMOylation of NR1I2 with SUMO3 IEA Drosophila melanogaster 2765 R-DRE-4755524 https://reactome.org/PathwayBrowser/#/R-DRE-4755524 SUMOylation of NR1I2 with SUMO3 IEA Danio rerio 2765 R-HSA-4755524 https://reactome.org/PathwayBrowser/#/R-HSA-4755524 SUMOylation of NR1I2 with SUMO3 TAS Homo sapiens 2765 R-HSA-9685655 https://reactome.org/PathwayBrowser/#/R-HSA-9685655 CTSL bind CTSL inhibitors TAS Homo sapiens 2765 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 2765 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 2765 R-HSA-9697085 https://reactome.org/PathwayBrowser/#/R-HSA-9697085 RNAP transcribes Mtb RNA polyanion TAS Homo sapiens 2765 R-HSA-9697086 https://reactome.org/PathwayBrowser/#/R-HSA-9697086 Rifampicin binds Mtb RNAP TAS Homo sapiens 2765 R-MMU-4755524 https://reactome.org/PathwayBrowser/#/R-MMU-4755524 SUMOylation of NR1I2 with SUMO3 IEA Mus musculus 2765 R-RNO-4755524 https://reactome.org/PathwayBrowser/#/R-RNO-4755524 SUMOylation of NR1I2 with SUMO3 IEA Rattus norvegicus 2765 R-SSC-4755524 https://reactome.org/PathwayBrowser/#/R-SSC-4755524 SUMOylation of NR1I2 with SUMO3 IEA Sus scrofa 2768 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 2768 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 2768 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 2768 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 2768 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 2768 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 2768 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 2768 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 2768 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 2768 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 2768 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 2768 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2768 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 2768 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 2768 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 2768 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 2768 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 2768 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 2768 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 2768 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 2768 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 2768 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 2768 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 2768 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 2768 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 2768 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 2768 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 2768 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 2768 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 2768 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2768 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 2768 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 2768 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 2768 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 2768 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 2768 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 2768 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 2768 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 2768 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 2768 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 2768 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 2768 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 277 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 277 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 277 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 277 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 277 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 277 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 277 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 277 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 2770 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 2770 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 2770 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 2770 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 2770 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 2770 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 2770 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 2770 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 2770 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 2770 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 2770 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 2770 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 2770 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 2770 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 2770 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 2770 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 2770 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 2770 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 2770 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 2770 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 2770 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 2770 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 2770 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 2770 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 2770 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 2770 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 2770 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 2770 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 2770 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 2778 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 2778 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 2778 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 2778 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 2778 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 2778 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 2778 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 2778 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 2778 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 2778 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 2778 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 2779 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 2779 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 2779 R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 2779 R-BTA-8963915 https://reactome.org/PathwayBrowser/#/R-BTA-8963915 1,25(OH)2D binds VDR IEA Bos taurus 2779 R-CEL-8963915 https://reactome.org/PathwayBrowser/#/R-CEL-8963915 1,25(OH)2D binds VDR IEA Caenorhabditis elegans 2779 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 2779 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 2779 R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 2779 R-CFA-8963915 https://reactome.org/PathwayBrowser/#/R-CFA-8963915 1,25(OH)2D binds VDR IEA Canis familiaris 2779 R-DME-8963915 https://reactome.org/PathwayBrowser/#/R-DME-8963915 1,25(OH)2D binds VDR IEA Drosophila melanogaster 2779 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 2779 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 2779 R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 2779 R-DRE-8963915 https://reactome.org/PathwayBrowser/#/R-DRE-8963915 1,25(OH)2D binds VDR IEA Danio rerio 2779 R-GGA-8963915 https://reactome.org/PathwayBrowser/#/R-GGA-8963915 1,25(OH)2D binds VDR IEA Gallus gallus 2779 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 2779 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 2779 R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 2779 R-HSA-5602004 https://reactome.org/PathwayBrowser/#/R-HSA-5602004 Defective CYP24A1 does not 24-hydroxylate CALTOL TAS Homo sapiens 2779 R-HSA-8963913 https://reactome.org/PathwayBrowser/#/R-HSA-8963913 1,25(OH)2D translocates from cytosol to nucleoplasm TAS Homo sapiens 2779 R-HSA-8963915 https://reactome.org/PathwayBrowser/#/R-HSA-8963915 1,25(OH)2D binds VDR TAS Homo sapiens 2779 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 2779 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 2779 R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 2779 R-MMU-8963915 https://reactome.org/PathwayBrowser/#/R-MMU-8963915 1,25(OH)2D binds VDR IEA Mus musculus 2779 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 2779 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 2779 R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 2779 R-RNO-8963915 https://reactome.org/PathwayBrowser/#/R-RNO-8963915 1,25(OH)2D binds VDR IEA Rattus norvegicus 2779 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 2779 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 2779 R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 2779 R-SSC-8963915 https://reactome.org/PathwayBrowser/#/R-SSC-8963915 1,25(OH)2D binds VDR IEA Sus scrofa 2779 R-XTR-8963915 https://reactome.org/PathwayBrowser/#/R-XTR-8963915 1,25(OH)2D binds VDR IEA Xenopus tropicalis 2781 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 2781 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 2781 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 2781 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 2781 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 2781 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 2781 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 2781 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 2781 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 2781 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 2781 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 2784 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 2784 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 2784 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 2784 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 2784 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 2784 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 2784 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 2784 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 2784 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 2784 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 2784 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 2785 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 2785 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 2785 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 2785 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 2785 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 2785 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 2785 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 2785 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 2785 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 2785 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 2785 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 2790 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 2790 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 2790 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 2790 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 2790 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 2790 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 2790 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 2790 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 2790 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 2790 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 2790 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 2791 R-BTA-9660192 https://reactome.org/PathwayBrowser/#/R-BTA-9660192 VDR agonists bind VDR IEA Bos taurus 2791 R-CEL-9660192 https://reactome.org/PathwayBrowser/#/R-CEL-9660192 VDR agonists bind VDR IEA Caenorhabditis elegans 2791 R-CFA-9660192 https://reactome.org/PathwayBrowser/#/R-CFA-9660192 VDR agonists bind VDR IEA Canis familiaris 2791 R-DME-9660192 https://reactome.org/PathwayBrowser/#/R-DME-9660192 VDR agonists bind VDR IEA Drosophila melanogaster 2791 R-DRE-9660192 https://reactome.org/PathwayBrowser/#/R-DRE-9660192 VDR agonists bind VDR IEA Danio rerio 2791 R-GGA-9660192 https://reactome.org/PathwayBrowser/#/R-GGA-9660192 VDR agonists bind VDR IEA Gallus gallus 2791 R-HSA-9660192 https://reactome.org/PathwayBrowser/#/R-HSA-9660192 VDR agonists bind VDR TAS Homo sapiens 2791 R-MMU-9660192 https://reactome.org/PathwayBrowser/#/R-MMU-9660192 VDR agonists bind VDR IEA Mus musculus 2791 R-RNO-9660192 https://reactome.org/PathwayBrowser/#/R-RNO-9660192 VDR agonists bind VDR IEA Rattus norvegicus 2791 R-SSC-9660192 https://reactome.org/PathwayBrowser/#/R-SSC-9660192 VDR agonists bind VDR IEA Sus scrofa 2791 R-XTR-9660192 https://reactome.org/PathwayBrowser/#/R-XTR-9660192 VDR agonists bind VDR IEA Xenopus tropicalis 2801 R-BTA-9716947 https://reactome.org/PathwayBrowser/#/R-BTA-9716947 ESR1 binds ESR1 agonists IEA Bos taurus 2801 R-DME-9716947 https://reactome.org/PathwayBrowser/#/R-DME-9716947 ESR1 binds ESR1 agonists IEA Drosophila melanogaster 2801 R-DRE-9716947 https://reactome.org/PathwayBrowser/#/R-DRE-9716947 ESR1 binds ESR1 agonists IEA Danio rerio 2801 R-GGA-9716947 https://reactome.org/PathwayBrowser/#/R-GGA-9716947 ESR1 binds ESR1 agonists IEA Gallus gallus 2801 R-HSA-9716947 https://reactome.org/PathwayBrowser/#/R-HSA-9716947 ESR1 binds ESR1 agonists TAS Homo sapiens 2801 R-MMU-9716947 https://reactome.org/PathwayBrowser/#/R-MMU-9716947 ESR1 binds ESR1 agonists IEA Mus musculus 2801 R-RNO-9716947 https://reactome.org/PathwayBrowser/#/R-RNO-9716947 ESR1 binds ESR1 agonists IEA Rattus norvegicus 2801 R-SSC-9716947 https://reactome.org/PathwayBrowser/#/R-SSC-9716947 ESR1 binds ESR1 agonists IEA Sus scrofa 2801 R-XTR-9716947 https://reactome.org/PathwayBrowser/#/R-XTR-9716947 ESR1 binds ESR1 agonists IEA Xenopus tropicalis 2803 R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 2803 R-BTA-192036 https://reactome.org/PathwayBrowser/#/R-BTA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Bos taurus 2803 R-CEL-192036 https://reactome.org/PathwayBrowser/#/R-CEL-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Caenorhabditis elegans 2803 R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 2803 R-DDI-192036 https://reactome.org/PathwayBrowser/#/R-DDI-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Dictyostelium discoideum 2803 R-DME-192036 https://reactome.org/PathwayBrowser/#/R-DME-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Drosophila melanogaster 2803 R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 2803 R-HSA-192010 https://reactome.org/PathwayBrowser/#/R-HSA-192010 5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix TAS Homo sapiens 2803 R-HSA-192036 https://reactome.org/PathwayBrowser/#/R-HSA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol TAS Homo sapiens 2803 R-HSA-5602170 https://reactome.org/PathwayBrowser/#/R-HSA-5602170 CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol TAS Homo sapiens 2803 R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 2803 R-MMU-192036 https://reactome.org/PathwayBrowser/#/R-MMU-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Mus musculus 2803 R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 2803 R-RNO-192036 https://reactome.org/PathwayBrowser/#/R-RNO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Rattus norvegicus 2803 R-SCE-192036 https://reactome.org/PathwayBrowser/#/R-SCE-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Saccharomyces cerevisiae 2803 R-SPO-192036 https://reactome.org/PathwayBrowser/#/R-SPO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Schizosaccharomyces pombe 2803 R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 2803 R-SSC-192036 https://reactome.org/PathwayBrowser/#/R-SSC-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Sus scrofa 2803 R-XTR-192036 https://reactome.org/PathwayBrowser/#/R-XTR-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Xenopus tropicalis 2805 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 2805 R-BTA-9726621 https://reactome.org/PathwayBrowser/#/R-BTA-9726621 PGR binds PGR antagonists IEA Bos taurus 2805 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 2805 R-CFA-9726621 https://reactome.org/PathwayBrowser/#/R-CFA-9726621 PGR binds PGR antagonists IEA Canis familiaris 2805 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 2805 R-DME-9726621 https://reactome.org/PathwayBrowser/#/R-DME-9726621 PGR binds PGR antagonists IEA Drosophila melanogaster 2805 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 2805 R-DRE-9726621 https://reactome.org/PathwayBrowser/#/R-DRE-9726621 PGR binds PGR antagonists IEA Danio rerio 2805 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 2805 R-GGA-9726621 https://reactome.org/PathwayBrowser/#/R-GGA-9726621 PGR binds PGR antagonists IEA Gallus gallus 2805 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 2805 R-HSA-9726621 https://reactome.org/PathwayBrowser/#/R-HSA-9726621 PGR binds PGR antagonists TAS Homo sapiens 2805 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 2805 R-MMU-9726621 https://reactome.org/PathwayBrowser/#/R-MMU-9726621 PGR binds PGR antagonists IEA Mus musculus 2805 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 2805 R-PFA-9726621 https://reactome.org/PathwayBrowser/#/R-PFA-9726621 PGR binds PGR antagonists IEA Plasmodium falciparum 2805 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 2805 R-RNO-9726621 https://reactome.org/PathwayBrowser/#/R-RNO-9726621 PGR binds PGR antagonists IEA Rattus norvegicus 2805 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 2805 R-SSC-9726621 https://reactome.org/PathwayBrowser/#/R-SSC-9726621 PGR binds PGR antagonists IEA Sus scrofa 2805 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 2806 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 2806 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 2806 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 2806 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 2806 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 2806 R-BTA-879585 https://reactome.org/PathwayBrowser/#/R-BTA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Bos taurus 2806 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 2806 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 2806 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 2806 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 2806 R-CEL-879585 https://reactome.org/PathwayBrowser/#/R-CEL-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Caenorhabditis elegans 2806 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 2806 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 2806 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 2806 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 2806 R-CFA-879585 https://reactome.org/PathwayBrowser/#/R-CFA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Canis familiaris 2806 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 2806 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 2806 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 2806 R-DME-879585 https://reactome.org/PathwayBrowser/#/R-DME-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Drosophila melanogaster 2806 R-DRE-879585 https://reactome.org/PathwayBrowser/#/R-DRE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Danio rerio 2806 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 2806 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 2806 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 2806 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 2806 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 2806 R-GGA-879585 https://reactome.org/PathwayBrowser/#/R-GGA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Gallus gallus 2806 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 2806 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 2806 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 2806 R-HSA-5627891 https://reactome.org/PathwayBrowser/#/R-HSA-5627891 Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol TAS Homo sapiens 2806 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 2806 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 2806 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 2806 R-HSA-879585 https://reactome.org/PathwayBrowser/#/R-HSA-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol TAS Homo sapiens 2806 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 2806 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 2806 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 2806 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 2806 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 2806 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 2806 R-MMU-879585 https://reactome.org/PathwayBrowser/#/R-MMU-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Mus musculus 2806 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 2806 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 2806 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 2806 R-RNO-879585 https://reactome.org/PathwayBrowser/#/R-RNO-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Rattus norvegicus 2806 R-SCE-879585 https://reactome.org/PathwayBrowser/#/R-SCE-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Saccharomyces cerevisiae 2806 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 2806 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 2806 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 2806 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 2806 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 2806 R-SSC-879585 https://reactome.org/PathwayBrowser/#/R-SSC-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Sus scrofa 2806 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 2806 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 2806 R-XTR-879585 https://reactome.org/PathwayBrowser/#/R-XTR-879585 SLC27A1,4,6 transport LCFAs from extracellular region to cytosol IEA Xenopus tropicalis 2818 R-BTA-176664 https://reactome.org/PathwayBrowser/#/R-BTA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Bos taurus 2818 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 2818 R-BTA-5693390 https://reactome.org/PathwayBrowser/#/R-BTA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Bos taurus 2818 R-BTA-5696822 https://reactome.org/PathwayBrowser/#/R-BTA-5696822 AKR1B15 reduces EST17b to E1 IEA Bos taurus 2818 R-BTA-6810594 https://reactome.org/PathwayBrowser/#/R-BTA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 2818 R-BTA-804969 https://reactome.org/PathwayBrowser/#/R-BTA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Bos taurus 2818 R-BTA-8862137 https://reactome.org/PathwayBrowser/#/R-BTA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 2818 R-BTA-9008258 https://reactome.org/PathwayBrowser/#/R-BTA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Bos taurus 2818 R-BTA-9008270 https://reactome.org/PathwayBrowser/#/R-BTA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Bos taurus 2818 R-BTA-9008271 https://reactome.org/PathwayBrowser/#/R-BTA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Bos taurus 2818 R-BTA-9008285 https://reactome.org/PathwayBrowser/#/R-BTA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Bos taurus 2818 R-BTA-9009526 https://reactome.org/PathwayBrowser/#/R-BTA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 2818 R-BTA-9009533 https://reactome.org/PathwayBrowser/#/R-BTA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Bos taurus 2818 R-BTA-9009536 https://reactome.org/PathwayBrowser/#/R-BTA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Bos taurus 2818 R-BTA-9009541 https://reactome.org/PathwayBrowser/#/R-BTA-9009541 ESR1 binds to TFF1 gene promoter IEA Bos taurus 2818 R-BTA-9023860 https://reactome.org/PathwayBrowser/#/R-BTA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Bos taurus 2818 R-BTA-9023861 https://reactome.org/PathwayBrowser/#/R-BTA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 2818 R-BTA-9023884 https://reactome.org/PathwayBrowser/#/R-BTA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Bos taurus 2818 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 2818 R-CEL-5696822 https://reactome.org/PathwayBrowser/#/R-CEL-5696822 AKR1B15 reduces EST17b to E1 IEA Caenorhabditis elegans 2818 R-CFA-176664 https://reactome.org/PathwayBrowser/#/R-CFA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Canis familiaris 2818 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 2818 R-CFA-5693390 https://reactome.org/PathwayBrowser/#/R-CFA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Canis familiaris 2818 R-CFA-804969 https://reactome.org/PathwayBrowser/#/R-CFA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Canis familiaris 2818 R-CFA-8862137 https://reactome.org/PathwayBrowser/#/R-CFA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Canis familiaris 2818 R-CFA-9008258 https://reactome.org/PathwayBrowser/#/R-CFA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Canis familiaris 2818 R-CFA-9008270 https://reactome.org/PathwayBrowser/#/R-CFA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Canis familiaris 2818 R-CFA-9008271 https://reactome.org/PathwayBrowser/#/R-CFA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Canis familiaris 2818 R-CFA-9008285 https://reactome.org/PathwayBrowser/#/R-CFA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Canis familiaris 2818 R-CFA-9009526 https://reactome.org/PathwayBrowser/#/R-CFA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 2818 R-CFA-9009533 https://reactome.org/PathwayBrowser/#/R-CFA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Canis familiaris 2818 R-CFA-9009536 https://reactome.org/PathwayBrowser/#/R-CFA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Canis familiaris 2818 R-CFA-9009541 https://reactome.org/PathwayBrowser/#/R-CFA-9009541 ESR1 binds to TFF1 gene promoter IEA Canis familiaris 2818 R-CFA-9023860 https://reactome.org/PathwayBrowser/#/R-CFA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Canis familiaris 2818 R-CFA-9023861 https://reactome.org/PathwayBrowser/#/R-CFA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 2818 R-CFA-9023884 https://reactome.org/PathwayBrowser/#/R-CFA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Canis familiaris 2818 R-DDI-5696822 https://reactome.org/PathwayBrowser/#/R-DDI-5696822 AKR1B15 reduces EST17b to E1 IEA Dictyostelium discoideum 2818 R-DDI-804969 https://reactome.org/PathwayBrowser/#/R-DDI-804969 HSD17B1 hydrogenates E1 to EST17b IEA Dictyostelium discoideum 2818 R-DDI-9023860 https://reactome.org/PathwayBrowser/#/R-DDI-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Dictyostelium discoideum 2818 R-DME-176664 https://reactome.org/PathwayBrowser/#/R-DME-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Drosophila melanogaster 2818 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 2818 R-DME-5693390 https://reactome.org/PathwayBrowser/#/R-DME-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Drosophila melanogaster 2818 R-DME-5696822 https://reactome.org/PathwayBrowser/#/R-DME-5696822 AKR1B15 reduces EST17b to E1 IEA Drosophila melanogaster 2818 R-DME-8862137 https://reactome.org/PathwayBrowser/#/R-DME-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Drosophila melanogaster 2818 R-DME-9008258 https://reactome.org/PathwayBrowser/#/R-DME-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Drosophila melanogaster 2818 R-DME-9008270 https://reactome.org/PathwayBrowser/#/R-DME-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Drosophila melanogaster 2818 R-DME-9008285 https://reactome.org/PathwayBrowser/#/R-DME-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Drosophila melanogaster 2818 R-DME-9009526 https://reactome.org/PathwayBrowser/#/R-DME-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 2818 R-DME-9009533 https://reactome.org/PathwayBrowser/#/R-DME-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Drosophila melanogaster 2818 R-DME-9009536 https://reactome.org/PathwayBrowser/#/R-DME-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Drosophila melanogaster 2818 R-DME-9009541 https://reactome.org/PathwayBrowser/#/R-DME-9009541 ESR1 binds to TFF1 gene promoter IEA Drosophila melanogaster 2818 R-DME-9023860 https://reactome.org/PathwayBrowser/#/R-DME-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Drosophila melanogaster 2818 R-DME-9023861 https://reactome.org/PathwayBrowser/#/R-DME-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 2818 R-DME-9023884 https://reactome.org/PathwayBrowser/#/R-DME-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Drosophila melanogaster 2818 R-DRE-176664 https://reactome.org/PathwayBrowser/#/R-DRE-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Danio rerio 2818 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 2818 R-DRE-5696822 https://reactome.org/PathwayBrowser/#/R-DRE-5696822 AKR1B15 reduces EST17b to E1 IEA Danio rerio 2818 R-DRE-6810594 https://reactome.org/PathwayBrowser/#/R-DRE-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Danio rerio 2818 R-DRE-9009526 https://reactome.org/PathwayBrowser/#/R-DRE-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Danio rerio 2818 R-DRE-9009533 https://reactome.org/PathwayBrowser/#/R-DRE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Danio rerio 2818 R-DRE-9009541 https://reactome.org/PathwayBrowser/#/R-DRE-9009541 ESR1 binds to TFF1 gene promoter IEA Danio rerio 2818 R-DRE-9023860 https://reactome.org/PathwayBrowser/#/R-DRE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Danio rerio 2818 R-GGA-176664 https://reactome.org/PathwayBrowser/#/R-GGA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Gallus gallus 2818 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 2818 R-GGA-5693390 https://reactome.org/PathwayBrowser/#/R-GGA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Gallus gallus 2818 R-GGA-5696822 https://reactome.org/PathwayBrowser/#/R-GGA-5696822 AKR1B15 reduces EST17b to E1 IEA Gallus gallus 2818 R-GGA-8862137 https://reactome.org/PathwayBrowser/#/R-GGA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Gallus gallus 2818 R-GGA-9008258 https://reactome.org/PathwayBrowser/#/R-GGA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Gallus gallus 2818 R-GGA-9008270 https://reactome.org/PathwayBrowser/#/R-GGA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Gallus gallus 2818 R-GGA-9008285 https://reactome.org/PathwayBrowser/#/R-GGA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Gallus gallus 2818 R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus 2818 R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus 2818 R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus 2818 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus 2818 R-GGA-9023884 https://reactome.org/PathwayBrowser/#/R-GGA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Gallus gallus 2818 R-HSA-176664 https://reactome.org/PathwayBrowser/#/R-HSA-176664 estrone + PAPS => estrone 3-sulfate + PAP TAS Homo sapiens 2818 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 2818 R-HSA-5693390 https://reactome.org/PathwayBrowser/#/R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 TAS Homo sapiens 2818 R-HSA-5696822 https://reactome.org/PathwayBrowser/#/R-HSA-5696822 AKR1B15 reduces EST17b to E1 TAS Homo sapiens 2818 R-HSA-6810594 https://reactome.org/PathwayBrowser/#/R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 2818 R-HSA-804969 https://reactome.org/PathwayBrowser/#/R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b TAS Homo sapiens 2818 R-HSA-8862137 https://reactome.org/PathwayBrowser/#/R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 2818 R-HSA-9008258 https://reactome.org/PathwayBrowser/#/R-HSA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene TAS Homo sapiens 2818 R-HSA-9008267 https://reactome.org/PathwayBrowser/#/R-HSA-9008267 ESR1 binds to TGFA gene promoter TAS Homo sapiens 2818 R-HSA-9008270 https://reactome.org/PathwayBrowser/#/R-HSA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene TAS Homo sapiens 2818 R-HSA-9008271 https://reactome.org/PathwayBrowser/#/R-HSA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter TAS Homo sapiens 2818 R-HSA-9008285 https://reactome.org/PathwayBrowser/#/R-HSA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 TAS Homo sapiens 2818 R-HSA-9008315 https://reactome.org/PathwayBrowser/#/R-HSA-9008315 TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen TAS Homo sapiens 2818 R-HSA-9009526 https://reactome.org/PathwayBrowser/#/R-HSA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 2818 R-HSA-9009533 https://reactome.org/PathwayBrowser/#/R-HSA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter TAS Homo sapiens 2818 R-HSA-9009536 https://reactome.org/PathwayBrowser/#/R-HSA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter TAS Homo sapiens 2818 R-HSA-9009541 https://reactome.org/PathwayBrowser/#/R-HSA-9009541 ESR1 binds to TFF1 gene promoter TAS Homo sapiens 2818 R-HSA-9023859 https://reactome.org/PathwayBrowser/#/R-HSA-9023859 Estrogen-responsive TFF1 gene expression TAS Homo sapiens 2818 R-HSA-9023860 https://reactome.org/PathwayBrowser/#/R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene TAS Homo sapiens 2818 R-HSA-9023861 https://reactome.org/PathwayBrowser/#/R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 2818 R-HSA-9023884 https://reactome.org/PathwayBrowser/#/R-HSA-9023884 NCOA1 recruits EP300 to TGFA promoter TAS Homo sapiens 2818 R-MMU-176664 https://reactome.org/PathwayBrowser/#/R-MMU-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Mus musculus 2818 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 2818 R-MMU-5693390 https://reactome.org/PathwayBrowser/#/R-MMU-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Mus musculus 2818 R-MMU-5696822 https://reactome.org/PathwayBrowser/#/R-MMU-5696822 AKR1B15 reduces EST17b to E1 IEA Mus musculus 2818 R-MMU-6810594 https://reactome.org/PathwayBrowser/#/R-MMU-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 2818 R-MMU-804969 https://reactome.org/PathwayBrowser/#/R-MMU-804969 HSD17B1 hydrogenates E1 to EST17b IEA Mus musculus 2818 R-MMU-8862137 https://reactome.org/PathwayBrowser/#/R-MMU-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 2818 R-MMU-9008258 https://reactome.org/PathwayBrowser/#/R-MMU-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Mus musculus 2818 R-MMU-9008270 https://reactome.org/PathwayBrowser/#/R-MMU-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Mus musculus 2818 R-MMU-9008271 https://reactome.org/PathwayBrowser/#/R-MMU-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Mus musculus 2818 R-MMU-9008285 https://reactome.org/PathwayBrowser/#/R-MMU-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Mus musculus 2818 R-MMU-9009526 https://reactome.org/PathwayBrowser/#/R-MMU-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 2818 R-MMU-9009533 https://reactome.org/PathwayBrowser/#/R-MMU-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Mus musculus 2818 R-MMU-9009536 https://reactome.org/PathwayBrowser/#/R-MMU-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Mus musculus 2818 R-MMU-9009541 https://reactome.org/PathwayBrowser/#/R-MMU-9009541 ESR1 binds to TFF1 gene promoter IEA Mus musculus 2818 R-MMU-9023860 https://reactome.org/PathwayBrowser/#/R-MMU-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Mus musculus 2818 R-MMU-9023861 https://reactome.org/PathwayBrowser/#/R-MMU-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 2818 R-MMU-9023884 https://reactome.org/PathwayBrowser/#/R-MMU-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Mus musculus 2818 R-RNO-176664 https://reactome.org/PathwayBrowser/#/R-RNO-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Rattus norvegicus 2818 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 2818 R-RNO-5693390 https://reactome.org/PathwayBrowser/#/R-RNO-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Rattus norvegicus 2818 R-RNO-5696822 https://reactome.org/PathwayBrowser/#/R-RNO-5696822 AKR1B15 reduces EST17b to E1 IEA Rattus norvegicus 2818 R-RNO-6810594 https://reactome.org/PathwayBrowser/#/R-RNO-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 2818 R-RNO-804969 https://reactome.org/PathwayBrowser/#/R-RNO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Rattus norvegicus 2818 R-RNO-8862137 https://reactome.org/PathwayBrowser/#/R-RNO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 2818 R-RNO-9008258 https://reactome.org/PathwayBrowser/#/R-RNO-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Rattus norvegicus 2818 R-RNO-9008270 https://reactome.org/PathwayBrowser/#/R-RNO-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Rattus norvegicus 2818 R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus 2818 R-RNO-9008285 https://reactome.org/PathwayBrowser/#/R-RNO-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Rattus norvegicus 2818 R-RNO-9009526 https://reactome.org/PathwayBrowser/#/R-RNO-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 2818 R-RNO-9009533 https://reactome.org/PathwayBrowser/#/R-RNO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Rattus norvegicus 2818 R-RNO-9009536 https://reactome.org/PathwayBrowser/#/R-RNO-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Rattus norvegicus 2818 R-RNO-9009541 https://reactome.org/PathwayBrowser/#/R-RNO-9009541 ESR1 binds to TFF1 gene promoter IEA Rattus norvegicus 2818 R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus 2818 R-RNO-9023861 https://reactome.org/PathwayBrowser/#/R-RNO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 2818 R-RNO-9023884 https://reactome.org/PathwayBrowser/#/R-RNO-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Rattus norvegicus 2818 R-SCE-5693390 https://reactome.org/PathwayBrowser/#/R-SCE-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Saccharomyces cerevisiae 2818 R-SCE-5696822 https://reactome.org/PathwayBrowser/#/R-SCE-5696822 AKR1B15 reduces EST17b to E1 IEA Saccharomyces cerevisiae 2818 R-SCE-9009533 https://reactome.org/PathwayBrowser/#/R-SCE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Saccharomyces cerevisiae 2818 R-SCE-9023860 https://reactome.org/PathwayBrowser/#/R-SCE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Saccharomyces cerevisiae 2818 R-SCE-9023861 https://reactome.org/PathwayBrowser/#/R-SCE-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Saccharomyces cerevisiae 2818 R-SPO-5696822 https://reactome.org/PathwayBrowser/#/R-SPO-5696822 AKR1B15 reduces EST17b to E1 IEA Schizosaccharomyces pombe 2818 R-SPO-804969 https://reactome.org/PathwayBrowser/#/R-SPO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Schizosaccharomyces pombe 2818 R-SPO-8862137 https://reactome.org/PathwayBrowser/#/R-SPO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Schizosaccharomyces pombe 2818 R-SPO-9009533 https://reactome.org/PathwayBrowser/#/R-SPO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Schizosaccharomyces pombe 2818 R-SPO-9023860 https://reactome.org/PathwayBrowser/#/R-SPO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Schizosaccharomyces pombe 2818 R-SPO-9023861 https://reactome.org/PathwayBrowser/#/R-SPO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Schizosaccharomyces pombe 2818 R-SSC-176664 https://reactome.org/PathwayBrowser/#/R-SSC-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Sus scrofa 2818 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 2818 R-SSC-5693390 https://reactome.org/PathwayBrowser/#/R-SSC-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Sus scrofa 2818 R-SSC-804969 https://reactome.org/PathwayBrowser/#/R-SSC-804969 HSD17B1 hydrogenates E1 to EST17b IEA Sus scrofa 2818 R-SSC-8862137 https://reactome.org/PathwayBrowser/#/R-SSC-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Sus scrofa 2818 R-SSC-9008258 https://reactome.org/PathwayBrowser/#/R-SSC-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Sus scrofa 2818 R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa 2818 R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa 2818 R-SSC-9008285 https://reactome.org/PathwayBrowser/#/R-SSC-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Sus scrofa 2818 R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 2818 R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa 2818 R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa 2818 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa 2818 R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 2818 R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa 2818 R-XTR-176664 https://reactome.org/PathwayBrowser/#/R-XTR-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Xenopus tropicalis 2818 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 2818 R-XTR-5693390 https://reactome.org/PathwayBrowser/#/R-XTR-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Xenopus tropicalis 2818 R-XTR-5696822 https://reactome.org/PathwayBrowser/#/R-XTR-5696822 AKR1B15 reduces EST17b to E1 IEA Xenopus tropicalis 2818 R-XTR-6810594 https://reactome.org/PathwayBrowser/#/R-XTR-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 2818 R-XTR-804969 https://reactome.org/PathwayBrowser/#/R-XTR-804969 HSD17B1 hydrogenates E1 to EST17b IEA Xenopus tropicalis 2818 R-XTR-8862137 https://reactome.org/PathwayBrowser/#/R-XTR-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 2818 R-XTR-9008258 https://reactome.org/PathwayBrowser/#/R-XTR-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Xenopus tropicalis 2818 R-XTR-9008285 https://reactome.org/PathwayBrowser/#/R-XTR-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Xenopus tropicalis 2818 R-XTR-9023860 https://reactome.org/PathwayBrowser/#/R-XTR-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Xenopus tropicalis 2820 R-BTA-9716913 https://reactome.org/PathwayBrowser/#/R-BTA-9716913 ESR1 binds ESR1 antagonists IEA Bos taurus 2820 R-DME-9716913 https://reactome.org/PathwayBrowser/#/R-DME-9716913 ESR1 binds ESR1 antagonists IEA Drosophila melanogaster 2820 R-DRE-9716913 https://reactome.org/PathwayBrowser/#/R-DRE-9716913 ESR1 binds ESR1 antagonists IEA Danio rerio 2820 R-GGA-9716913 https://reactome.org/PathwayBrowser/#/R-GGA-9716913 ESR1 binds ESR1 antagonists IEA Gallus gallus 2820 R-HSA-9716913 https://reactome.org/PathwayBrowser/#/R-HSA-9716913 ESR1 binds ESR1 antagonists TAS Homo sapiens 2820 R-MMU-9716913 https://reactome.org/PathwayBrowser/#/R-MMU-9716913 ESR1 binds ESR1 antagonists IEA Mus musculus 2820 R-RNO-9716913 https://reactome.org/PathwayBrowser/#/R-RNO-9716913 ESR1 binds ESR1 antagonists IEA Rattus norvegicus 2820 R-SSC-9716913 https://reactome.org/PathwayBrowser/#/R-SSC-9716913 ESR1 binds ESR1 antagonists IEA Sus scrofa 2820 R-XTR-9716913 https://reactome.org/PathwayBrowser/#/R-XTR-9716913 ESR1 binds ESR1 antagonists IEA Xenopus tropicalis 2821 R-BTA-9008258 https://reactome.org/PathwayBrowser/#/R-BTA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Bos taurus 2821 R-BTA-9008270 https://reactome.org/PathwayBrowser/#/R-BTA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Bos taurus 2821 R-BTA-9008271 https://reactome.org/PathwayBrowser/#/R-BTA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Bos taurus 2821 R-BTA-9008285 https://reactome.org/PathwayBrowser/#/R-BTA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Bos taurus 2821 R-BTA-9009526 https://reactome.org/PathwayBrowser/#/R-BTA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 2821 R-BTA-9009533 https://reactome.org/PathwayBrowser/#/R-BTA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Bos taurus 2821 R-BTA-9009536 https://reactome.org/PathwayBrowser/#/R-BTA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Bos taurus 2821 R-BTA-9009541 https://reactome.org/PathwayBrowser/#/R-BTA-9009541 ESR1 binds to TFF1 gene promoter IEA Bos taurus 2821 R-BTA-9023860 https://reactome.org/PathwayBrowser/#/R-BTA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Bos taurus 2821 R-BTA-9023861 https://reactome.org/PathwayBrowser/#/R-BTA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 2821 R-BTA-9023884 https://reactome.org/PathwayBrowser/#/R-BTA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Bos taurus 2821 R-CFA-9008258 https://reactome.org/PathwayBrowser/#/R-CFA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Canis familiaris 2821 R-CFA-9008270 https://reactome.org/PathwayBrowser/#/R-CFA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Canis familiaris 2821 R-CFA-9008271 https://reactome.org/PathwayBrowser/#/R-CFA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Canis familiaris 2821 R-CFA-9008285 https://reactome.org/PathwayBrowser/#/R-CFA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Canis familiaris 2821 R-CFA-9009526 https://reactome.org/PathwayBrowser/#/R-CFA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 2821 R-CFA-9009533 https://reactome.org/PathwayBrowser/#/R-CFA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Canis familiaris 2821 R-CFA-9009536 https://reactome.org/PathwayBrowser/#/R-CFA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Canis familiaris 2821 R-CFA-9009541 https://reactome.org/PathwayBrowser/#/R-CFA-9009541 ESR1 binds to TFF1 gene promoter IEA Canis familiaris 2821 R-CFA-9023860 https://reactome.org/PathwayBrowser/#/R-CFA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Canis familiaris 2821 R-CFA-9023861 https://reactome.org/PathwayBrowser/#/R-CFA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 2821 R-CFA-9023884 https://reactome.org/PathwayBrowser/#/R-CFA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Canis familiaris 2821 R-DDI-9023860 https://reactome.org/PathwayBrowser/#/R-DDI-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Dictyostelium discoideum 2821 R-DME-9008258 https://reactome.org/PathwayBrowser/#/R-DME-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Drosophila melanogaster 2821 R-DME-9008270 https://reactome.org/PathwayBrowser/#/R-DME-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Drosophila melanogaster 2821 R-DME-9008285 https://reactome.org/PathwayBrowser/#/R-DME-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Drosophila melanogaster 2821 R-DME-9009526 https://reactome.org/PathwayBrowser/#/R-DME-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 2821 R-DME-9009533 https://reactome.org/PathwayBrowser/#/R-DME-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Drosophila melanogaster 2821 R-DME-9009536 https://reactome.org/PathwayBrowser/#/R-DME-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Drosophila melanogaster 2821 R-DME-9009541 https://reactome.org/PathwayBrowser/#/R-DME-9009541 ESR1 binds to TFF1 gene promoter IEA Drosophila melanogaster 2821 R-DME-9023860 https://reactome.org/PathwayBrowser/#/R-DME-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Drosophila melanogaster 2821 R-DME-9023861 https://reactome.org/PathwayBrowser/#/R-DME-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 2821 R-DME-9023884 https://reactome.org/PathwayBrowser/#/R-DME-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Drosophila melanogaster 2821 R-DRE-9009526 https://reactome.org/PathwayBrowser/#/R-DRE-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Danio rerio 2821 R-DRE-9009533 https://reactome.org/PathwayBrowser/#/R-DRE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Danio rerio 2821 R-DRE-9009541 https://reactome.org/PathwayBrowser/#/R-DRE-9009541 ESR1 binds to TFF1 gene promoter IEA Danio rerio 2821 R-DRE-9023860 https://reactome.org/PathwayBrowser/#/R-DRE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Danio rerio 2821 R-GGA-9008258 https://reactome.org/PathwayBrowser/#/R-GGA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Gallus gallus 2821 R-GGA-9008270 https://reactome.org/PathwayBrowser/#/R-GGA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Gallus gallus 2821 R-GGA-9008285 https://reactome.org/PathwayBrowser/#/R-GGA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Gallus gallus 2821 R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus 2821 R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus 2821 R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus 2821 R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus 2821 R-GGA-9023884 https://reactome.org/PathwayBrowser/#/R-GGA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Gallus gallus 2821 R-HSA-9008258 https://reactome.org/PathwayBrowser/#/R-HSA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene TAS Homo sapiens 2821 R-HSA-9008267 https://reactome.org/PathwayBrowser/#/R-HSA-9008267 ESR1 binds to TGFA gene promoter TAS Homo sapiens 2821 R-HSA-9008270 https://reactome.org/PathwayBrowser/#/R-HSA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene TAS Homo sapiens 2821 R-HSA-9008271 https://reactome.org/PathwayBrowser/#/R-HSA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter TAS Homo sapiens 2821 R-HSA-9008285 https://reactome.org/PathwayBrowser/#/R-HSA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 TAS Homo sapiens 2821 R-HSA-9008315 https://reactome.org/PathwayBrowser/#/R-HSA-9008315 TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen TAS Homo sapiens 2821 R-HSA-9009526 https://reactome.org/PathwayBrowser/#/R-HSA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 2821 R-HSA-9009533 https://reactome.org/PathwayBrowser/#/R-HSA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter TAS Homo sapiens 2821 R-HSA-9009536 https://reactome.org/PathwayBrowser/#/R-HSA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter TAS Homo sapiens 2821 R-HSA-9009541 https://reactome.org/PathwayBrowser/#/R-HSA-9009541 ESR1 binds to TFF1 gene promoter TAS Homo sapiens 2821 R-HSA-9023859 https://reactome.org/PathwayBrowser/#/R-HSA-9023859 Estrogen-responsive TFF1 gene expression TAS Homo sapiens 2821 R-HSA-9023860 https://reactome.org/PathwayBrowser/#/R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene TAS Homo sapiens 2821 R-HSA-9023861 https://reactome.org/PathwayBrowser/#/R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 2821 R-HSA-9023884 https://reactome.org/PathwayBrowser/#/R-HSA-9023884 NCOA1 recruits EP300 to TGFA promoter TAS Homo sapiens 2821 R-MMU-9008258 https://reactome.org/PathwayBrowser/#/R-MMU-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Mus musculus 2821 R-MMU-9008270 https://reactome.org/PathwayBrowser/#/R-MMU-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Mus musculus 2821 R-MMU-9008271 https://reactome.org/PathwayBrowser/#/R-MMU-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Mus musculus 2821 R-MMU-9008285 https://reactome.org/PathwayBrowser/#/R-MMU-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Mus musculus 2821 R-MMU-9009526 https://reactome.org/PathwayBrowser/#/R-MMU-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 2821 R-MMU-9009533 https://reactome.org/PathwayBrowser/#/R-MMU-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Mus musculus 2821 R-MMU-9009536 https://reactome.org/PathwayBrowser/#/R-MMU-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Mus musculus 2821 R-MMU-9009541 https://reactome.org/PathwayBrowser/#/R-MMU-9009541 ESR1 binds to TFF1 gene promoter IEA Mus musculus 2821 R-MMU-9023860 https://reactome.org/PathwayBrowser/#/R-MMU-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Mus musculus 2821 R-MMU-9023861 https://reactome.org/PathwayBrowser/#/R-MMU-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 2821 R-MMU-9023884 https://reactome.org/PathwayBrowser/#/R-MMU-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Mus musculus 2821 R-RNO-9008258 https://reactome.org/PathwayBrowser/#/R-RNO-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Rattus norvegicus 2821 R-RNO-9008270 https://reactome.org/PathwayBrowser/#/R-RNO-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Rattus norvegicus 2821 R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus 2821 R-RNO-9008285 https://reactome.org/PathwayBrowser/#/R-RNO-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Rattus norvegicus 2821 R-RNO-9009526 https://reactome.org/PathwayBrowser/#/R-RNO-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 2821 R-RNO-9009533 https://reactome.org/PathwayBrowser/#/R-RNO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Rattus norvegicus 2821 R-RNO-9009536 https://reactome.org/PathwayBrowser/#/R-RNO-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Rattus norvegicus 2821 R-RNO-9009541 https://reactome.org/PathwayBrowser/#/R-RNO-9009541 ESR1 binds to TFF1 gene promoter IEA Rattus norvegicus 2821 R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus 2821 R-RNO-9023861 https://reactome.org/PathwayBrowser/#/R-RNO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 2821 R-RNO-9023884 https://reactome.org/PathwayBrowser/#/R-RNO-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Rattus norvegicus 2821 R-SCE-9009533 https://reactome.org/PathwayBrowser/#/R-SCE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Saccharomyces cerevisiae 2821 R-SCE-9023860 https://reactome.org/PathwayBrowser/#/R-SCE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Saccharomyces cerevisiae 2821 R-SCE-9023861 https://reactome.org/PathwayBrowser/#/R-SCE-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Saccharomyces cerevisiae 2821 R-SPO-9009533 https://reactome.org/PathwayBrowser/#/R-SPO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Schizosaccharomyces pombe 2821 R-SPO-9023860 https://reactome.org/PathwayBrowser/#/R-SPO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Schizosaccharomyces pombe 2821 R-SPO-9023861 https://reactome.org/PathwayBrowser/#/R-SPO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Schizosaccharomyces pombe 2821 R-SSC-9008258 https://reactome.org/PathwayBrowser/#/R-SSC-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Sus scrofa 2821 R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa 2821 R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa 2821 R-SSC-9008285 https://reactome.org/PathwayBrowser/#/R-SSC-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Sus scrofa 2821 R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 2821 R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa 2821 R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa 2821 R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa 2821 R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 2821 R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa 2821 R-XTR-9008258 https://reactome.org/PathwayBrowser/#/R-XTR-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Xenopus tropicalis 2821 R-XTR-9008285 https://reactome.org/PathwayBrowser/#/R-XTR-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Xenopus tropicalis 2821 R-XTR-9023860 https://reactome.org/PathwayBrowser/#/R-XTR-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Xenopus tropicalis 2844 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 2844 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 2844 R-BTA-109415 https://reactome.org/PathwayBrowser/#/R-BTA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Bos taurus 2844 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 2844 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 2844 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 2844 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 2844 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 2844 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 2844 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 2844 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 2844 R-BTA-174401 https://reactome.org/PathwayBrowser/#/R-BTA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Bos taurus 2844 R-BTA-379044 https://reactome.org/PathwayBrowser/#/R-BTA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Bos taurus 2844 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2844 R-BTA-418904 https://reactome.org/PathwayBrowser/#/R-BTA-418904 A1 and A3 receptors bind adenosine IEA Bos taurus 2844 R-BTA-418925 https://reactome.org/PathwayBrowser/#/R-BTA-418925 ADORA2A,B bind Ade-Rib IEA Bos taurus 2844 R-BTA-5684862 https://reactome.org/PathwayBrowser/#/R-BTA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region IEA Bos taurus 2844 R-BTA-5693346 https://reactome.org/PathwayBrowser/#/R-BTA-5693346 CECRI deaminates Ade-Rib to Ino IEA Bos taurus 2844 R-BTA-727740 https://reactome.org/PathwayBrowser/#/R-BTA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 2844 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 2844 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 2844 R-BTA-727768 https://reactome.org/PathwayBrowser/#/R-BTA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Bos taurus 2844 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 2844 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2844 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2844 R-BTA-8857692 https://reactome.org/PathwayBrowser/#/R-BTA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Bos taurus 2844 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 2844 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 2844 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 2844 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 2844 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 2844 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 2844 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 2844 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 2844 R-CEL-174401 https://reactome.org/PathwayBrowser/#/R-CEL-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Caenorhabditis elegans 2844 R-CEL-379044 https://reactome.org/PathwayBrowser/#/R-CEL-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Caenorhabditis elegans 2844 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 2844 R-CEL-418904 https://reactome.org/PathwayBrowser/#/R-CEL-418904 A1 and A3 receptors bind adenosine IEA Caenorhabditis elegans 2844 R-CEL-418925 https://reactome.org/PathwayBrowser/#/R-CEL-418925 ADORA2A,B bind Ade-Rib IEA Caenorhabditis elegans 2844 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 2844 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 2844 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 2844 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 2844 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 2844 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 2844 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 2844 R-CFA-109415 https://reactome.org/PathwayBrowser/#/R-CFA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Canis familiaris 2844 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 2844 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 2844 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 2844 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 2844 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 2844 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 2844 R-CFA-174401 https://reactome.org/PathwayBrowser/#/R-CFA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Canis familiaris 2844 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2844 R-CFA-418904 https://reactome.org/PathwayBrowser/#/R-CFA-418904 A1 and A3 receptors bind adenosine IEA Canis familiaris 2844 R-CFA-418925 https://reactome.org/PathwayBrowser/#/R-CFA-418925 ADORA2A,B bind Ade-Rib IEA Canis familiaris 2844 R-CFA-5684862 https://reactome.org/PathwayBrowser/#/R-CFA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region IEA Canis familiaris 2844 R-CFA-727740 https://reactome.org/PathwayBrowser/#/R-CFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 2844 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 2844 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 2844 R-CFA-727768 https://reactome.org/PathwayBrowser/#/R-CFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Canis familiaris 2844 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 2844 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2844 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2844 R-CFA-8857692 https://reactome.org/PathwayBrowser/#/R-CFA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Canis familiaris 2844 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 2844 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 2844 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 2844 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 2844 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 2844 R-DDI-174401 https://reactome.org/PathwayBrowser/#/R-DDI-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Dictyostelium discoideum 2844 R-DDI-5693346 https://reactome.org/PathwayBrowser/#/R-DDI-5693346 CECRI deaminates Ade-Rib to Ino IEA Dictyostelium discoideum 2844 R-DDI-727740 https://reactome.org/PathwayBrowser/#/R-DDI-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 2844 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 2844 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 2844 R-DDI-727768 https://reactome.org/PathwayBrowser/#/R-DDI-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Dictyostelium discoideum 2844 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 2844 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 2844 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 2844 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 2844 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 2844 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 2844 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 2844 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 2844 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 2844 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 2844 R-DME-174401 https://reactome.org/PathwayBrowser/#/R-DME-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Drosophila melanogaster 2844 R-DME-379044 https://reactome.org/PathwayBrowser/#/R-DME-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Drosophila melanogaster 2844 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 2844 R-DME-418904 https://reactome.org/PathwayBrowser/#/R-DME-418904 A1 and A3 receptors bind adenosine IEA Drosophila melanogaster 2844 R-DME-418925 https://reactome.org/PathwayBrowser/#/R-DME-418925 ADORA2A,B bind Ade-Rib IEA Drosophila melanogaster 2844 R-DME-5693346 https://reactome.org/PathwayBrowser/#/R-DME-5693346 CECRI deaminates Ade-Rib to Ino IEA Drosophila melanogaster 2844 R-DME-727740 https://reactome.org/PathwayBrowser/#/R-DME-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 2844 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 2844 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 2844 R-DME-727768 https://reactome.org/PathwayBrowser/#/R-DME-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Drosophila melanogaster 2844 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 2844 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 2844 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 2844 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 2844 R-DRE-109415 https://reactome.org/PathwayBrowser/#/R-DRE-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Danio rerio 2844 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 2844 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 2844 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 2844 R-DRE-174401 https://reactome.org/PathwayBrowser/#/R-DRE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Danio rerio 2844 R-DRE-418925 https://reactome.org/PathwayBrowser/#/R-DRE-418925 ADORA2A,B bind Ade-Rib IEA Danio rerio 2844 R-DRE-5693346 https://reactome.org/PathwayBrowser/#/R-DRE-5693346 CECRI deaminates Ade-Rib to Ino IEA Danio rerio 2844 R-DRE-727740 https://reactome.org/PathwayBrowser/#/R-DRE-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 2844 R-DRE-727768 https://reactome.org/PathwayBrowser/#/R-DRE-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Danio rerio 2844 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 2844 R-DRE-8857692 https://reactome.org/PathwayBrowser/#/R-DRE-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Danio rerio 2844 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 2844 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 2844 R-GGA-109415 https://reactome.org/PathwayBrowser/#/R-GGA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Gallus gallus 2844 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 2844 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 2844 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 2844 R-GGA-174401 https://reactome.org/PathwayBrowser/#/R-GGA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Gallus gallus 2844 R-GGA-379044 https://reactome.org/PathwayBrowser/#/R-GGA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Gallus gallus 2844 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 2844 R-GGA-418904 https://reactome.org/PathwayBrowser/#/R-GGA-418904 A1 and A3 receptors bind adenosine IEA Gallus gallus 2844 R-GGA-418925 https://reactome.org/PathwayBrowser/#/R-GGA-418925 ADORA2A,B bind Ade-Rib IEA Gallus gallus 2844 R-GGA-5684862 https://reactome.org/PathwayBrowser/#/R-GGA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region IEA Gallus gallus 2844 R-GGA-5693346 https://reactome.org/PathwayBrowser/#/R-GGA-5693346 CECRI deaminates Ade-Rib to Ino IEA Gallus gallus 2844 R-GGA-727740 https://reactome.org/PathwayBrowser/#/R-GGA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 2844 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 2844 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 2844 R-GGA-727768 https://reactome.org/PathwayBrowser/#/R-GGA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Gallus gallus 2844 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 2844 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 2844 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 2844 R-GGA-8857692 https://reactome.org/PathwayBrowser/#/R-GGA-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Gallus gallus 2844 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 2844 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 2844 R-HSA-109415 https://reactome.org/PathwayBrowser/#/R-HSA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] TAS Homo sapiens 2844 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 2844 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 2844 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 2844 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 2844 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 2844 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 2844 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 2844 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 2844 R-HSA-174401 https://reactome.org/PathwayBrowser/#/R-HSA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy TAS Homo sapiens 2844 R-HSA-187661 https://reactome.org/PathwayBrowser/#/R-HSA-187661 Ade-Rib binds AODORA2A and NTRK1,2 IEA Homo sapiens 2844 R-HSA-2161193 https://reactome.org/PathwayBrowser/#/R-HSA-2161193 abacavir + AMP => abacavir monophosphate + adenosine TAS Homo sapiens 2844 R-HSA-2408532 https://reactome.org/PathwayBrowser/#/R-HSA-2408532 AdeSeHCys is hydrolysed to SeHCys by AHCY IEA Homo sapiens 2844 R-HSA-379044 https://reactome.org/PathwayBrowser/#/R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs TAS Homo sapiens 2844 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2844 R-HSA-418904 https://reactome.org/PathwayBrowser/#/R-HSA-418904 A1 and A3 receptors bind adenosine TAS Homo sapiens 2844 R-HSA-418925 https://reactome.org/PathwayBrowser/#/R-HSA-418925 ADORA2A,B bind Ade-Rib TAS Homo sapiens 2844 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 2844 R-HSA-5684862 https://reactome.org/PathwayBrowser/#/R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region TAS Homo sapiens 2844 R-HSA-5693346 https://reactome.org/PathwayBrowser/#/R-HSA-5693346 CECRI deaminates Ade-Rib to Ino TAS Homo sapiens 2844 R-HSA-727740 https://reactome.org/PathwayBrowser/#/R-HSA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 2844 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 2844 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 2844 R-HSA-727768 https://reactome.org/PathwayBrowser/#/R-HSA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 TAS Homo sapiens 2844 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 2844 R-HSA-744886 https://reactome.org/PathwayBrowser/#/R-HSA-744886 The Ligand:GPCR:Gs complex dissociates TAS Homo sapiens 2844 R-HSA-744887 https://reactome.org/PathwayBrowser/#/R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs TAS Homo sapiens 2844 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2844 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2844 R-HSA-8857692 https://reactome.org/PathwayBrowser/#/R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA TAS Homo sapiens 2844 R-HSA-9613023 https://reactome.org/PathwayBrowser/#/R-HSA-9613023 NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates IEA Homo sapiens 2844 R-HSA-9660819 https://reactome.org/PathwayBrowser/#/R-HSA-9660819 ADORA2B:Ade-Rib:GsGTP dissociates TAS Homo sapiens 2844 R-HSA-9660824 https://reactome.org/PathwayBrowser/#/R-HSA-9660824 ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs TAS Homo sapiens 2844 R-HSA-9660828 https://reactome.org/PathwayBrowser/#/R-HSA-9660828 ADORA2B:Ade-Rib binds heterometric G-protein Gs TAS Homo sapiens 2844 R-HSA-9660829 https://reactome.org/PathwayBrowser/#/R-HSA-9660829 ADORA2B binds Ade-Rib TAS Homo sapiens 2844 R-HSA-9734745 https://reactome.org/PathwayBrowser/#/R-HSA-9734745 Defective ADA does not deaminate (deoxy)adenosine TAS Homo sapiens 2844 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 2844 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 2844 R-MMU-109415 https://reactome.org/PathwayBrowser/#/R-MMU-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Mus musculus 2844 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 2844 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 2844 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 2844 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 2844 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 2844 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 2844 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 2844 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 2844 R-MMU-174401 https://reactome.org/PathwayBrowser/#/R-MMU-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Mus musculus 2844 R-MMU-379044 https://reactome.org/PathwayBrowser/#/R-MMU-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Mus musculus 2844 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2844 R-MMU-418904 https://reactome.org/PathwayBrowser/#/R-MMU-418904 A1 and A3 receptors bind adenosine IEA Mus musculus 2844 R-MMU-418925 https://reactome.org/PathwayBrowser/#/R-MMU-418925 ADORA2A,B bind Ade-Rib IEA Mus musculus 2844 R-MMU-5684862 https://reactome.org/PathwayBrowser/#/R-MMU-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region IEA Mus musculus 2844 R-MMU-727740 https://reactome.org/PathwayBrowser/#/R-MMU-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 2844 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 2844 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 2844 R-MMU-727768 https://reactome.org/PathwayBrowser/#/R-MMU-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Mus musculus 2844 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 2844 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2844 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2844 R-MMU-8857692 https://reactome.org/PathwayBrowser/#/R-MMU-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Mus musculus 2844 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 2844 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 2844 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 2844 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 2844 R-PFA-727740 https://reactome.org/PathwayBrowser/#/R-PFA-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 2844 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 2844 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 2844 R-PFA-727768 https://reactome.org/PathwayBrowser/#/R-PFA-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Plasmodium falciparum 2844 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 2844 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 2844 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 2844 R-RNO-109415 https://reactome.org/PathwayBrowser/#/R-RNO-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Rattus norvegicus 2844 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 2844 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 2844 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 2844 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 2844 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 2844 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 2844 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 2844 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 2844 R-RNO-174401 https://reactome.org/PathwayBrowser/#/R-RNO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Rattus norvegicus 2844 R-RNO-189618 https://reactome.org/PathwayBrowser/#/R-RNO-189618 TrkA activation by adenosine A2a receptor TAS Rattus norvegicus 2844 R-RNO-2408512 https://reactome.org/PathwayBrowser/#/R-RNO-2408512 AdeSeHCys is hydrolysed to SeHCys by Ahcy TAS Rattus norvegicus 2844 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2844 R-RNO-418904 https://reactome.org/PathwayBrowser/#/R-RNO-418904 A1 and A3 receptors bind adenosine IEA Rattus norvegicus 2844 R-RNO-418925 https://reactome.org/PathwayBrowser/#/R-RNO-418925 ADORA2A,B bind Ade-Rib IEA Rattus norvegicus 2844 R-RNO-5684862 https://reactome.org/PathwayBrowser/#/R-RNO-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region IEA Rattus norvegicus 2844 R-RNO-727740 https://reactome.org/PathwayBrowser/#/R-RNO-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 2844 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 2844 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 2844 R-RNO-727768 https://reactome.org/PathwayBrowser/#/R-RNO-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Rattus norvegicus 2844 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 2844 R-RNO-8857692 https://reactome.org/PathwayBrowser/#/R-RNO-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Rattus norvegicus 2844 R-RNO-9613030 https://reactome.org/PathwayBrowser/#/R-RNO-9613030 Ntrk1,2,3 in Ade-Rib:Adora2a:Ntrk1,2,3 autophosphorylates TAS Rattus norvegicus 2844 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 2844 R-SCE-174401 https://reactome.org/PathwayBrowser/#/R-SCE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Saccharomyces cerevisiae 2844 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 2844 R-SPO-174401 https://reactome.org/PathwayBrowser/#/R-SPO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Schizosaccharomyces pombe 2844 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 2844 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 2844 R-SSC-109415 https://reactome.org/PathwayBrowser/#/R-SSC-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Sus scrofa 2844 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 2844 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 2844 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 2844 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 2844 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 2844 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 2844 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 2844 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 2844 R-SSC-174401 https://reactome.org/PathwayBrowser/#/R-SSC-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Sus scrofa 2844 R-SSC-379044 https://reactome.org/PathwayBrowser/#/R-SSC-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Sus scrofa 2844 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2844 R-SSC-418904 https://reactome.org/PathwayBrowser/#/R-SSC-418904 A1 and A3 receptors bind adenosine IEA Sus scrofa 2844 R-SSC-418925 https://reactome.org/PathwayBrowser/#/R-SSC-418925 ADORA2A,B bind Ade-Rib IEA Sus scrofa 2844 R-SSC-5684862 https://reactome.org/PathwayBrowser/#/R-SSC-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region IEA Sus scrofa 2844 R-SSC-5693346 https://reactome.org/PathwayBrowser/#/R-SSC-5693346 CECRI deaminates Ade-Rib to Ino IEA Sus scrofa 2844 R-SSC-727740 https://reactome.org/PathwayBrowser/#/R-SSC-727740 Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 2844 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 2844 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 2844 R-SSC-727768 https://reactome.org/PathwayBrowser/#/R-SSC-727768 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 IEA Sus scrofa 2844 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 2844 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2844 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2844 R-SSC-8857692 https://reactome.org/PathwayBrowser/#/R-SSC-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Sus scrofa 2844 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 2844 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 2844 R-XTR-109415 https://reactome.org/PathwayBrowser/#/R-XTR-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Xenopus tropicalis 2844 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 2844 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 2844 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 2844 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 2844 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 2844 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 2844 R-XTR-174401 https://reactome.org/PathwayBrowser/#/R-XTR-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Xenopus tropicalis 2844 R-XTR-379044 https://reactome.org/PathwayBrowser/#/R-XTR-379044 Liganded Gs-activating GPCR acts as a GEF for Gs IEA Xenopus tropicalis 2844 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 2844 R-XTR-418925 https://reactome.org/PathwayBrowser/#/R-XTR-418925 ADORA2A,B bind Ade-Rib IEA Xenopus tropicalis 2844 R-XTR-5693346 https://reactome.org/PathwayBrowser/#/R-XTR-5693346 CECRI deaminates Ade-Rib to Ino IEA Xenopus tropicalis 2844 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 2844 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 2844 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2844 R-XTR-8857692 https://reactome.org/PathwayBrowser/#/R-XTR-8857692 RNA demethylases demethylate N6-methyladenosine RNA IEA Xenopus tropicalis 2856 R-BTA-469659 https://reactome.org/PathwayBrowser/#/R-BTA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Bos taurus 2856 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 2856 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 2856 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 2856 R-BTA-5625717 https://reactome.org/PathwayBrowser/#/R-BTA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Bos taurus 2856 R-BTA-5625738 https://reactome.org/PathwayBrowser/#/R-BTA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Bos taurus 2856 R-BTA-5625745 https://reactome.org/PathwayBrowser/#/R-BTA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Bos taurus 2856 R-BTA-5625774 https://reactome.org/PathwayBrowser/#/R-BTA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Bos taurus 2856 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 2856 R-BTA-5625796 https://reactome.org/PathwayBrowser/#/R-BTA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Bos taurus 2856 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 2856 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 2856 R-BTA-5625849 https://reactome.org/PathwayBrowser/#/R-BTA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Bos taurus 2856 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 2856 R-BTA-8877902 https://reactome.org/PathwayBrowser/#/R-BTA-8877902 Activated AR binds RUNX2 IEA Bos taurus 2856 R-BTA-9705713 https://reactome.org/PathwayBrowser/#/R-BTA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Bos taurus 2856 R-BTA-9705714 https://reactome.org/PathwayBrowser/#/R-BTA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Bos taurus 2856 R-BTA-9705925 https://reactome.org/PathwayBrowser/#/R-BTA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Bos taurus 2856 R-CEL-469659 https://reactome.org/PathwayBrowser/#/R-CEL-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 2856 R-CEL-9705713 https://reactome.org/PathwayBrowser/#/R-CEL-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 2856 R-CEL-9705714 https://reactome.org/PathwayBrowser/#/R-CEL-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 2856 R-CFA-469659 https://reactome.org/PathwayBrowser/#/R-CFA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Canis familiaris 2856 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 2856 R-CFA-5625717 https://reactome.org/PathwayBrowser/#/R-CFA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Canis familiaris 2856 R-CFA-5625738 https://reactome.org/PathwayBrowser/#/R-CFA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Canis familiaris 2856 R-CFA-5625745 https://reactome.org/PathwayBrowser/#/R-CFA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Canis familiaris 2856 R-CFA-5625774 https://reactome.org/PathwayBrowser/#/R-CFA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Canis familiaris 2856 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 2856 R-CFA-5625796 https://reactome.org/PathwayBrowser/#/R-CFA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Canis familiaris 2856 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 2856 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 2856 R-CFA-5625849 https://reactome.org/PathwayBrowser/#/R-CFA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Canis familiaris 2856 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 2856 R-CFA-8877902 https://reactome.org/PathwayBrowser/#/R-CFA-8877902 Activated AR binds RUNX2 IEA Canis familiaris 2856 R-CFA-9705713 https://reactome.org/PathwayBrowser/#/R-CFA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Canis familiaris 2856 R-CFA-9705714 https://reactome.org/PathwayBrowser/#/R-CFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Canis familiaris 2856 R-CFA-9705925 https://reactome.org/PathwayBrowser/#/R-CFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Canis familiaris 2856 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 2856 R-DDI-9705714 https://reactome.org/PathwayBrowser/#/R-DDI-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Dictyostelium discoideum 2856 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 2856 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 2856 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 2856 R-DME-5625717 https://reactome.org/PathwayBrowser/#/R-DME-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Drosophila melanogaster 2856 R-DME-5625738 https://reactome.org/PathwayBrowser/#/R-DME-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Drosophila melanogaster 2856 R-DME-5625745 https://reactome.org/PathwayBrowser/#/R-DME-5625745 PKN1 stimulates association of AR with NCOA2 IEA Drosophila melanogaster 2856 R-DME-5625774 https://reactome.org/PathwayBrowser/#/R-DME-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Drosophila melanogaster 2856 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 2856 R-DME-5625796 https://reactome.org/PathwayBrowser/#/R-DME-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 2856 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 2856 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 2856 R-DME-5625849 https://reactome.org/PathwayBrowser/#/R-DME-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 2856 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 2856 R-DME-8877902 https://reactome.org/PathwayBrowser/#/R-DME-8877902 Activated AR binds RUNX2 IEA Drosophila melanogaster 2856 R-DME-9705714 https://reactome.org/PathwayBrowser/#/R-DME-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Drosophila melanogaster 2856 R-DME-9705925 https://reactome.org/PathwayBrowser/#/R-DME-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2856 R-DRE-469659 https://reactome.org/PathwayBrowser/#/R-DRE-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Danio rerio 2856 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 2856 R-DRE-5625717 https://reactome.org/PathwayBrowser/#/R-DRE-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Danio rerio 2856 R-DRE-5625738 https://reactome.org/PathwayBrowser/#/R-DRE-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Danio rerio 2856 R-DRE-5625745 https://reactome.org/PathwayBrowser/#/R-DRE-5625745 PKN1 stimulates association of AR with NCOA2 IEA Danio rerio 2856 R-DRE-5625774 https://reactome.org/PathwayBrowser/#/R-DRE-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Danio rerio 2856 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 2856 R-DRE-5625796 https://reactome.org/PathwayBrowser/#/R-DRE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Danio rerio 2856 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 2856 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 2856 R-DRE-8877902 https://reactome.org/PathwayBrowser/#/R-DRE-8877902 Activated AR binds RUNX2 IEA Danio rerio 2856 R-DRE-9705713 https://reactome.org/PathwayBrowser/#/R-DRE-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Danio rerio 2856 R-DRE-9705714 https://reactome.org/PathwayBrowser/#/R-DRE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Danio rerio 2856 R-DRE-9705925 https://reactome.org/PathwayBrowser/#/R-DRE-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Danio rerio 2856 R-GGA-469659 https://reactome.org/PathwayBrowser/#/R-GGA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Gallus gallus 2856 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 2856 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 2856 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 2856 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 2856 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus 2856 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 2856 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 2856 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus 2856 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 2856 R-GGA-8877902 https://reactome.org/PathwayBrowser/#/R-GGA-8877902 Activated AR binds RUNX2 IEA Gallus gallus 2856 R-GGA-9705713 https://reactome.org/PathwayBrowser/#/R-GGA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Gallus gallus 2856 R-GGA-9705714 https://reactome.org/PathwayBrowser/#/R-GGA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Gallus gallus 2856 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus 2856 R-HSA-469659 https://reactome.org/PathwayBrowser/#/R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST TAS Homo sapiens 2856 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 2856 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 2856 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 2856 R-HSA-5625717 https://reactome.org/PathwayBrowser/#/R-HSA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) TAS Homo sapiens 2856 R-HSA-5625738 https://reactome.org/PathwayBrowser/#/R-HSA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus TAS Homo sapiens 2856 R-HSA-5625745 https://reactome.org/PathwayBrowser/#/R-HSA-5625745 PKN1 stimulates association of AR with NCOA2 TAS Homo sapiens 2856 R-HSA-5625774 https://reactome.org/PathwayBrowser/#/R-HSA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes TAS Homo sapiens 2856 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 2856 R-HSA-5625796 https://reactome.org/PathwayBrowser/#/R-HSA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters TAS Homo sapiens 2856 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 2856 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 2856 R-HSA-5625849 https://reactome.org/PathwayBrowser/#/R-HSA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters TAS Homo sapiens 2856 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 2856 R-HSA-5625883 https://reactome.org/PathwayBrowser/#/R-HSA-5625883 PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 TAS Homo sapiens 2856 R-HSA-8877902 https://reactome.org/PathwayBrowser/#/R-HSA-8877902 Activated AR binds RUNX2 TAS Homo sapiens 2856 R-HSA-8877918 https://reactome.org/PathwayBrowser/#/R-HSA-8877918 RUNX2:MAF complex binds the BGLAP gene promoter IEA Homo sapiens 2856 R-HSA-9705713 https://reactome.org/PathwayBrowser/#/R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST TAS Homo sapiens 2856 R-HSA-9705714 https://reactome.org/PathwayBrowser/#/R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST TAS Homo sapiens 2856 R-HSA-9705925 https://reactome.org/PathwayBrowser/#/R-HSA-9705925 Androgens binds AR (in the HSP90 chaperone complex) TAS Homo sapiens 2856 R-MMU-469659 https://reactome.org/PathwayBrowser/#/R-MMU-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Mus musculus 2856 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 2856 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 2856 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 2856 R-MMU-5625717 https://reactome.org/PathwayBrowser/#/R-MMU-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Mus musculus 2856 R-MMU-5625738 https://reactome.org/PathwayBrowser/#/R-MMU-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Mus musculus 2856 R-MMU-5625745 https://reactome.org/PathwayBrowser/#/R-MMU-5625745 PKN1 stimulates association of AR with NCOA2 IEA Mus musculus 2856 R-MMU-8877902 https://reactome.org/PathwayBrowser/#/R-MMU-8877902 Activated AR binds RUNX2 IEA Mus musculus 2856 R-MMU-9705713 https://reactome.org/PathwayBrowser/#/R-MMU-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Mus musculus 2856 R-MMU-9705714 https://reactome.org/PathwayBrowser/#/R-MMU-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Mus musculus 2856 R-MMU-9705925 https://reactome.org/PathwayBrowser/#/R-MMU-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Mus musculus 2856 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 2856 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 2856 R-PFA-9705714 https://reactome.org/PathwayBrowser/#/R-PFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Plasmodium falciparum 2856 R-PFA-9705925 https://reactome.org/PathwayBrowser/#/R-PFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2856 R-RNO-469659 https://reactome.org/PathwayBrowser/#/R-RNO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 2856 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 2856 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 2856 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 2856 R-RNO-5625717 https://reactome.org/PathwayBrowser/#/R-RNO-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Rattus norvegicus 2856 R-RNO-5625738 https://reactome.org/PathwayBrowser/#/R-RNO-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Rattus norvegicus 2856 R-RNO-5625745 https://reactome.org/PathwayBrowser/#/R-RNO-5625745 PKN1 stimulates association of AR with NCOA2 IEA Rattus norvegicus 2856 R-RNO-5625774 https://reactome.org/PathwayBrowser/#/R-RNO-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Rattus norvegicus 2856 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 2856 R-RNO-5625796 https://reactome.org/PathwayBrowser/#/R-RNO-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Rattus norvegicus 2856 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 2856 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 2856 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus 2856 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 2856 R-RNO-9705713 https://reactome.org/PathwayBrowser/#/R-RNO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 2856 R-RNO-9705714 https://reactome.org/PathwayBrowser/#/R-RNO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 2856 R-RNO-9705925 https://reactome.org/PathwayBrowser/#/R-RNO-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Rattus norvegicus 2856 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2856 R-SCE-5625796 https://reactome.org/PathwayBrowser/#/R-SCE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2856 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2856 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2856 R-SCE-5625849 https://reactome.org/PathwayBrowser/#/R-SCE-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2856 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2856 R-SCE-9705714 https://reactome.org/PathwayBrowser/#/R-SCE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Saccharomyces cerevisiae 2856 R-SPO-469659 https://reactome.org/PathwayBrowser/#/R-SPO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 2856 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2856 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2856 R-SPO-5625849 https://reactome.org/PathwayBrowser/#/R-SPO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2856 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2856 R-SPO-9705713 https://reactome.org/PathwayBrowser/#/R-SPO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 2856 R-SPO-9705714 https://reactome.org/PathwayBrowser/#/R-SPO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 2856 R-SSC-469659 https://reactome.org/PathwayBrowser/#/R-SSC-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Sus scrofa 2856 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 2856 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 2856 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 2856 R-SSC-5625717 https://reactome.org/PathwayBrowser/#/R-SSC-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Sus scrofa 2856 R-SSC-5625738 https://reactome.org/PathwayBrowser/#/R-SSC-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Sus scrofa 2856 R-SSC-5625745 https://reactome.org/PathwayBrowser/#/R-SSC-5625745 PKN1 stimulates association of AR with NCOA2 IEA Sus scrofa 2856 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa 2856 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 2856 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa 2856 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 2856 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 2856 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa 2856 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 2856 R-SSC-8877902 https://reactome.org/PathwayBrowser/#/R-SSC-8877902 Activated AR binds RUNX2 IEA Sus scrofa 2856 R-SSC-9705713 https://reactome.org/PathwayBrowser/#/R-SSC-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Sus scrofa 2856 R-SSC-9705714 https://reactome.org/PathwayBrowser/#/R-SSC-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Sus scrofa 2856 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa 2856 R-XTR-469659 https://reactome.org/PathwayBrowser/#/R-XTR-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 2856 R-XTR-8877902 https://reactome.org/PathwayBrowser/#/R-XTR-8877902 Activated AR binds RUNX2 IEA Xenopus tropicalis 2856 R-XTR-9705713 https://reactome.org/PathwayBrowser/#/R-XTR-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 2856 R-XTR-9705714 https://reactome.org/PathwayBrowser/#/R-XTR-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 2856 R-XTR-9705925 https://reactome.org/PathwayBrowser/#/R-XTR-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2858 R-BTA-193064 https://reactome.org/PathwayBrowser/#/R-BTA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Bos taurus 2858 R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 2858 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 2858 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 2858 R-BTA-469659 https://reactome.org/PathwayBrowser/#/R-BTA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Bos taurus 2858 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 2858 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 2858 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 2858 R-BTA-5625717 https://reactome.org/PathwayBrowser/#/R-BTA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Bos taurus 2858 R-BTA-5625738 https://reactome.org/PathwayBrowser/#/R-BTA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Bos taurus 2858 R-BTA-5625745 https://reactome.org/PathwayBrowser/#/R-BTA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Bos taurus 2858 R-BTA-5625774 https://reactome.org/PathwayBrowser/#/R-BTA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Bos taurus 2858 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 2858 R-BTA-5625796 https://reactome.org/PathwayBrowser/#/R-BTA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Bos taurus 2858 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 2858 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 2858 R-BTA-5625849 https://reactome.org/PathwayBrowser/#/R-BTA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Bos taurus 2858 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 2858 R-BTA-8877902 https://reactome.org/PathwayBrowser/#/R-BTA-8877902 Activated AR binds RUNX2 IEA Bos taurus 2858 R-BTA-9705713 https://reactome.org/PathwayBrowser/#/R-BTA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Bos taurus 2858 R-BTA-9705714 https://reactome.org/PathwayBrowser/#/R-BTA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Bos taurus 2858 R-BTA-9705925 https://reactome.org/PathwayBrowser/#/R-BTA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Bos taurus 2858 R-CEL-193064 https://reactome.org/PathwayBrowser/#/R-CEL-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Caenorhabditis elegans 2858 R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 2858 R-CEL-469659 https://reactome.org/PathwayBrowser/#/R-CEL-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 2858 R-CEL-9705713 https://reactome.org/PathwayBrowser/#/R-CEL-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 2858 R-CEL-9705714 https://reactome.org/PathwayBrowser/#/R-CEL-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 2858 R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 2858 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 2858 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 2858 R-CFA-469659 https://reactome.org/PathwayBrowser/#/R-CFA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Canis familiaris 2858 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 2858 R-CFA-5625717 https://reactome.org/PathwayBrowser/#/R-CFA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Canis familiaris 2858 R-CFA-5625738 https://reactome.org/PathwayBrowser/#/R-CFA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Canis familiaris 2858 R-CFA-5625745 https://reactome.org/PathwayBrowser/#/R-CFA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Canis familiaris 2858 R-CFA-5625774 https://reactome.org/PathwayBrowser/#/R-CFA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Canis familiaris 2858 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 2858 R-CFA-5625796 https://reactome.org/PathwayBrowser/#/R-CFA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Canis familiaris 2858 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 2858 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 2858 R-CFA-5625849 https://reactome.org/PathwayBrowser/#/R-CFA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Canis familiaris 2858 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 2858 R-CFA-8877902 https://reactome.org/PathwayBrowser/#/R-CFA-8877902 Activated AR binds RUNX2 IEA Canis familiaris 2858 R-CFA-9705713 https://reactome.org/PathwayBrowser/#/R-CFA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Canis familiaris 2858 R-CFA-9705714 https://reactome.org/PathwayBrowser/#/R-CFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Canis familiaris 2858 R-CFA-9705925 https://reactome.org/PathwayBrowser/#/R-CFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Canis familiaris 2858 R-DDI-193064 https://reactome.org/PathwayBrowser/#/R-DDI-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Dictyostelium discoideum 2858 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 2858 R-DDI-9705714 https://reactome.org/PathwayBrowser/#/R-DDI-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Dictyostelium discoideum 2858 R-DME-193064 https://reactome.org/PathwayBrowser/#/R-DME-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Drosophila melanogaster 2858 R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 2858 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 2858 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 2858 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 2858 R-DME-5625717 https://reactome.org/PathwayBrowser/#/R-DME-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Drosophila melanogaster 2858 R-DME-5625738 https://reactome.org/PathwayBrowser/#/R-DME-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Drosophila melanogaster 2858 R-DME-5625745 https://reactome.org/PathwayBrowser/#/R-DME-5625745 PKN1 stimulates association of AR with NCOA2 IEA Drosophila melanogaster 2858 R-DME-5625774 https://reactome.org/PathwayBrowser/#/R-DME-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Drosophila melanogaster 2858 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 2858 R-DME-5625796 https://reactome.org/PathwayBrowser/#/R-DME-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 2858 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 2858 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 2858 R-DME-5625849 https://reactome.org/PathwayBrowser/#/R-DME-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 2858 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 2858 R-DME-8877902 https://reactome.org/PathwayBrowser/#/R-DME-8877902 Activated AR binds RUNX2 IEA Drosophila melanogaster 2858 R-DME-9705714 https://reactome.org/PathwayBrowser/#/R-DME-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Drosophila melanogaster 2858 R-DME-9705925 https://reactome.org/PathwayBrowser/#/R-DME-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2858 R-DRE-193064 https://reactome.org/PathwayBrowser/#/R-DRE-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Danio rerio 2858 R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 2858 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 2858 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 2858 R-DRE-469659 https://reactome.org/PathwayBrowser/#/R-DRE-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Danio rerio 2858 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 2858 R-DRE-5625717 https://reactome.org/PathwayBrowser/#/R-DRE-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Danio rerio 2858 R-DRE-5625738 https://reactome.org/PathwayBrowser/#/R-DRE-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Danio rerio 2858 R-DRE-5625745 https://reactome.org/PathwayBrowser/#/R-DRE-5625745 PKN1 stimulates association of AR with NCOA2 IEA Danio rerio 2858 R-DRE-5625774 https://reactome.org/PathwayBrowser/#/R-DRE-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Danio rerio 2858 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 2858 R-DRE-5625796 https://reactome.org/PathwayBrowser/#/R-DRE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Danio rerio 2858 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 2858 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 2858 R-DRE-8877902 https://reactome.org/PathwayBrowser/#/R-DRE-8877902 Activated AR binds RUNX2 IEA Danio rerio 2858 R-DRE-9705713 https://reactome.org/PathwayBrowser/#/R-DRE-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Danio rerio 2858 R-DRE-9705714 https://reactome.org/PathwayBrowser/#/R-DRE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Danio rerio 2858 R-DRE-9705925 https://reactome.org/PathwayBrowser/#/R-DRE-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Danio rerio 2858 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus 2858 R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 2858 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 2858 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 2858 R-GGA-469659 https://reactome.org/PathwayBrowser/#/R-GGA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Gallus gallus 2858 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 2858 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 2858 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 2858 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 2858 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus 2858 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 2858 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 2858 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus 2858 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 2858 R-GGA-8877902 https://reactome.org/PathwayBrowser/#/R-GGA-8877902 Activated AR binds RUNX2 IEA Gallus gallus 2858 R-GGA-9705713 https://reactome.org/PathwayBrowser/#/R-GGA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Gallus gallus 2858 R-GGA-9705714 https://reactome.org/PathwayBrowser/#/R-GGA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Gallus gallus 2858 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus 2858 R-HSA-193064 https://reactome.org/PathwayBrowser/#/R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST TAS Homo sapiens 2858 R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 2858 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 2858 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 2858 R-HSA-469659 https://reactome.org/PathwayBrowser/#/R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST TAS Homo sapiens 2858 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 2858 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 2858 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 2858 R-HSA-5625717 https://reactome.org/PathwayBrowser/#/R-HSA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) TAS Homo sapiens 2858 R-HSA-5625738 https://reactome.org/PathwayBrowser/#/R-HSA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus TAS Homo sapiens 2858 R-HSA-5625745 https://reactome.org/PathwayBrowser/#/R-HSA-5625745 PKN1 stimulates association of AR with NCOA2 TAS Homo sapiens 2858 R-HSA-5625774 https://reactome.org/PathwayBrowser/#/R-HSA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes TAS Homo sapiens 2858 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 2858 R-HSA-5625796 https://reactome.org/PathwayBrowser/#/R-HSA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters TAS Homo sapiens 2858 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 2858 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 2858 R-HSA-5625849 https://reactome.org/PathwayBrowser/#/R-HSA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters TAS Homo sapiens 2858 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 2858 R-HSA-5625883 https://reactome.org/PathwayBrowser/#/R-HSA-5625883 PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 TAS Homo sapiens 2858 R-HSA-8877902 https://reactome.org/PathwayBrowser/#/R-HSA-8877902 Activated AR binds RUNX2 TAS Homo sapiens 2858 R-HSA-8877918 https://reactome.org/PathwayBrowser/#/R-HSA-8877918 RUNX2:MAF complex binds the BGLAP gene promoter IEA Homo sapiens 2858 R-HSA-9705713 https://reactome.org/PathwayBrowser/#/R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST TAS Homo sapiens 2858 R-HSA-9705714 https://reactome.org/PathwayBrowser/#/R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST TAS Homo sapiens 2858 R-HSA-9705925 https://reactome.org/PathwayBrowser/#/R-HSA-9705925 Androgens binds AR (in the HSP90 chaperone complex) TAS Homo sapiens 2858 R-MMU-193064 https://reactome.org/PathwayBrowser/#/R-MMU-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Mus musculus 2858 R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 2858 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 2858 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 2858 R-MMU-469659 https://reactome.org/PathwayBrowser/#/R-MMU-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Mus musculus 2858 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 2858 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 2858 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 2858 R-MMU-5625717 https://reactome.org/PathwayBrowser/#/R-MMU-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Mus musculus 2858 R-MMU-5625738 https://reactome.org/PathwayBrowser/#/R-MMU-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Mus musculus 2858 R-MMU-5625745 https://reactome.org/PathwayBrowser/#/R-MMU-5625745 PKN1 stimulates association of AR with NCOA2 IEA Mus musculus 2858 R-MMU-8877902 https://reactome.org/PathwayBrowser/#/R-MMU-8877902 Activated AR binds RUNX2 IEA Mus musculus 2858 R-MMU-9705713 https://reactome.org/PathwayBrowser/#/R-MMU-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Mus musculus 2858 R-MMU-9705714 https://reactome.org/PathwayBrowser/#/R-MMU-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Mus musculus 2858 R-MMU-9705925 https://reactome.org/PathwayBrowser/#/R-MMU-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Mus musculus 2858 R-PFA-193064 https://reactome.org/PathwayBrowser/#/R-PFA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Plasmodium falciparum 2858 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 2858 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 2858 R-PFA-9705714 https://reactome.org/PathwayBrowser/#/R-PFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Plasmodium falciparum 2858 R-PFA-9705925 https://reactome.org/PathwayBrowser/#/R-PFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2858 R-RNO-193064 https://reactome.org/PathwayBrowser/#/R-RNO-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Rattus norvegicus 2858 R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 2858 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 2858 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 2858 R-RNO-469659 https://reactome.org/PathwayBrowser/#/R-RNO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 2858 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 2858 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 2858 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 2858 R-RNO-5625717 https://reactome.org/PathwayBrowser/#/R-RNO-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Rattus norvegicus 2858 R-RNO-5625738 https://reactome.org/PathwayBrowser/#/R-RNO-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Rattus norvegicus 2858 R-RNO-5625745 https://reactome.org/PathwayBrowser/#/R-RNO-5625745 PKN1 stimulates association of AR with NCOA2 IEA Rattus norvegicus 2858 R-RNO-5625774 https://reactome.org/PathwayBrowser/#/R-RNO-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Rattus norvegicus 2858 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 2858 R-RNO-5625796 https://reactome.org/PathwayBrowser/#/R-RNO-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Rattus norvegicus 2858 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 2858 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 2858 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus 2858 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 2858 R-RNO-9705713 https://reactome.org/PathwayBrowser/#/R-RNO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 2858 R-RNO-9705714 https://reactome.org/PathwayBrowser/#/R-RNO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 2858 R-RNO-9705925 https://reactome.org/PathwayBrowser/#/R-RNO-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Rattus norvegicus 2858 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2858 R-SCE-5625796 https://reactome.org/PathwayBrowser/#/R-SCE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2858 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2858 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2858 R-SCE-5625849 https://reactome.org/PathwayBrowser/#/R-SCE-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2858 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2858 R-SCE-9705714 https://reactome.org/PathwayBrowser/#/R-SCE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Saccharomyces cerevisiae 2858 R-SPO-469659 https://reactome.org/PathwayBrowser/#/R-SPO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 2858 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2858 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2858 R-SPO-5625849 https://reactome.org/PathwayBrowser/#/R-SPO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2858 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2858 R-SPO-9705713 https://reactome.org/PathwayBrowser/#/R-SPO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 2858 R-SPO-9705714 https://reactome.org/PathwayBrowser/#/R-SPO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 2858 R-SSC-193064 https://reactome.org/PathwayBrowser/#/R-SSC-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Sus scrofa 2858 R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 2858 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 2858 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 2858 R-SSC-469659 https://reactome.org/PathwayBrowser/#/R-SSC-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Sus scrofa 2858 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 2858 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 2858 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 2858 R-SSC-5625717 https://reactome.org/PathwayBrowser/#/R-SSC-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Sus scrofa 2858 R-SSC-5625738 https://reactome.org/PathwayBrowser/#/R-SSC-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Sus scrofa 2858 R-SSC-5625745 https://reactome.org/PathwayBrowser/#/R-SSC-5625745 PKN1 stimulates association of AR with NCOA2 IEA Sus scrofa 2858 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa 2858 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 2858 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa 2858 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 2858 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 2858 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa 2858 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 2858 R-SSC-8877902 https://reactome.org/PathwayBrowser/#/R-SSC-8877902 Activated AR binds RUNX2 IEA Sus scrofa 2858 R-SSC-9705713 https://reactome.org/PathwayBrowser/#/R-SSC-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Sus scrofa 2858 R-SSC-9705714 https://reactome.org/PathwayBrowser/#/R-SSC-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Sus scrofa 2858 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa 2858 R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 2858 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 2858 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 2858 R-XTR-469659 https://reactome.org/PathwayBrowser/#/R-XTR-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 2858 R-XTR-8877902 https://reactome.org/PathwayBrowser/#/R-XTR-8877902 Activated AR binds RUNX2 IEA Xenopus tropicalis 2858 R-XTR-9705713 https://reactome.org/PathwayBrowser/#/R-XTR-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 2858 R-XTR-9705714 https://reactome.org/PathwayBrowser/#/R-XTR-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 2858 R-XTR-9705925 https://reactome.org/PathwayBrowser/#/R-XTR-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2860 R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 2860 R-BTA-193064 https://reactome.org/PathwayBrowser/#/R-BTA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Bos taurus 2860 R-BTA-193073 https://reactome.org/PathwayBrowser/#/R-BTA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Bos taurus 2860 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 2860 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 2860 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 2860 R-BTA-5625717 https://reactome.org/PathwayBrowser/#/R-BTA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Bos taurus 2860 R-BTA-5625738 https://reactome.org/PathwayBrowser/#/R-BTA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Bos taurus 2860 R-BTA-5625745 https://reactome.org/PathwayBrowser/#/R-BTA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Bos taurus 2860 R-BTA-5625774 https://reactome.org/PathwayBrowser/#/R-BTA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Bos taurus 2860 R-BTA-5625784 https://reactome.org/PathwayBrowser/#/R-BTA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Bos taurus 2860 R-BTA-5625796 https://reactome.org/PathwayBrowser/#/R-BTA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Bos taurus 2860 R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 2860 R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 2860 R-BTA-5625849 https://reactome.org/PathwayBrowser/#/R-BTA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Bos taurus 2860 R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 2860 R-BTA-8877902 https://reactome.org/PathwayBrowser/#/R-BTA-8877902 Activated AR binds RUNX2 IEA Bos taurus 2860 R-BTA-9705925 https://reactome.org/PathwayBrowser/#/R-BTA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Bos taurus 2860 R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 2860 R-CEL-193064 https://reactome.org/PathwayBrowser/#/R-CEL-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Caenorhabditis elegans 2860 R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 2860 R-CFA-193073 https://reactome.org/PathwayBrowser/#/R-CFA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Canis familiaris 2860 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 2860 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 2860 R-CFA-5625717 https://reactome.org/PathwayBrowser/#/R-CFA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Canis familiaris 2860 R-CFA-5625738 https://reactome.org/PathwayBrowser/#/R-CFA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Canis familiaris 2860 R-CFA-5625745 https://reactome.org/PathwayBrowser/#/R-CFA-5625745 PKN1 stimulates association of AR with NCOA2 IEA Canis familiaris 2860 R-CFA-5625774 https://reactome.org/PathwayBrowser/#/R-CFA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Canis familiaris 2860 R-CFA-5625784 https://reactome.org/PathwayBrowser/#/R-CFA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Canis familiaris 2860 R-CFA-5625796 https://reactome.org/PathwayBrowser/#/R-CFA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Canis familiaris 2860 R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 2860 R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 2860 R-CFA-5625849 https://reactome.org/PathwayBrowser/#/R-CFA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Canis familiaris 2860 R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 2860 R-CFA-8877902 https://reactome.org/PathwayBrowser/#/R-CFA-8877902 Activated AR binds RUNX2 IEA Canis familiaris 2860 R-CFA-9705925 https://reactome.org/PathwayBrowser/#/R-CFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Canis familiaris 2860 R-DDI-193064 https://reactome.org/PathwayBrowser/#/R-DDI-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Dictyostelium discoideum 2860 R-DDI-5625784 https://reactome.org/PathwayBrowser/#/R-DDI-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Dictyostelium discoideum 2860 R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 2860 R-DME-193064 https://reactome.org/PathwayBrowser/#/R-DME-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Drosophila melanogaster 2860 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 2860 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 2860 R-DME-5625717 https://reactome.org/PathwayBrowser/#/R-DME-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Drosophila melanogaster 2860 R-DME-5625738 https://reactome.org/PathwayBrowser/#/R-DME-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Drosophila melanogaster 2860 R-DME-5625745 https://reactome.org/PathwayBrowser/#/R-DME-5625745 PKN1 stimulates association of AR with NCOA2 IEA Drosophila melanogaster 2860 R-DME-5625774 https://reactome.org/PathwayBrowser/#/R-DME-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Drosophila melanogaster 2860 R-DME-5625784 https://reactome.org/PathwayBrowser/#/R-DME-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Drosophila melanogaster 2860 R-DME-5625796 https://reactome.org/PathwayBrowser/#/R-DME-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 2860 R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 2860 R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 2860 R-DME-5625849 https://reactome.org/PathwayBrowser/#/R-DME-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Drosophila melanogaster 2860 R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 2860 R-DME-8877902 https://reactome.org/PathwayBrowser/#/R-DME-8877902 Activated AR binds RUNX2 IEA Drosophila melanogaster 2860 R-DME-9705925 https://reactome.org/PathwayBrowser/#/R-DME-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2860 R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 2860 R-DRE-193064 https://reactome.org/PathwayBrowser/#/R-DRE-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Danio rerio 2860 R-DRE-193073 https://reactome.org/PathwayBrowser/#/R-DRE-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Danio rerio 2860 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 2860 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 2860 R-DRE-5625717 https://reactome.org/PathwayBrowser/#/R-DRE-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Danio rerio 2860 R-DRE-5625738 https://reactome.org/PathwayBrowser/#/R-DRE-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Danio rerio 2860 R-DRE-5625745 https://reactome.org/PathwayBrowser/#/R-DRE-5625745 PKN1 stimulates association of AR with NCOA2 IEA Danio rerio 2860 R-DRE-5625774 https://reactome.org/PathwayBrowser/#/R-DRE-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Danio rerio 2860 R-DRE-5625784 https://reactome.org/PathwayBrowser/#/R-DRE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Danio rerio 2860 R-DRE-5625796 https://reactome.org/PathwayBrowser/#/R-DRE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Danio rerio 2860 R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 2860 R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 2860 R-DRE-8877902 https://reactome.org/PathwayBrowser/#/R-DRE-8877902 Activated AR binds RUNX2 IEA Danio rerio 2860 R-DRE-9705925 https://reactome.org/PathwayBrowser/#/R-DRE-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Danio rerio 2860 R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 2860 R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus 2860 R-GGA-193073 https://reactome.org/PathwayBrowser/#/R-GGA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Gallus gallus 2860 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 2860 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 2860 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 2860 R-GGA-5625784 https://reactome.org/PathwayBrowser/#/R-GGA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Gallus gallus 2860 R-GGA-5625796 https://reactome.org/PathwayBrowser/#/R-GGA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Gallus gallus 2860 R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 2860 R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 2860 R-GGA-5625849 https://reactome.org/PathwayBrowser/#/R-GGA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Gallus gallus 2860 R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 2860 R-GGA-8877902 https://reactome.org/PathwayBrowser/#/R-GGA-8877902 Activated AR binds RUNX2 IEA Gallus gallus 2860 R-GGA-9705925 https://reactome.org/PathwayBrowser/#/R-GGA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Gallus gallus 2860 R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 2860 R-HSA-193064 https://reactome.org/PathwayBrowser/#/R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST TAS Homo sapiens 2860 R-HSA-193073 https://reactome.org/PathwayBrowser/#/R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST TAS Homo sapiens 2860 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 2860 R-HSA-5601849 https://reactome.org/PathwayBrowser/#/R-HSA-5601849 Defective CYP19A1 does not convert ANDST to E1 TAS Homo sapiens 2860 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 2860 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 2860 R-HSA-5625717 https://reactome.org/PathwayBrowser/#/R-HSA-5625717 Phosphorylated PKN1 binds androgen receptor (AR) TAS Homo sapiens 2860 R-HSA-5625738 https://reactome.org/PathwayBrowser/#/R-HSA-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus TAS Homo sapiens 2860 R-HSA-5625745 https://reactome.org/PathwayBrowser/#/R-HSA-5625745 PKN1 stimulates association of AR with NCOA2 TAS Homo sapiens 2860 R-HSA-5625774 https://reactome.org/PathwayBrowser/#/R-HSA-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes TAS Homo sapiens 2860 R-HSA-5625784 https://reactome.org/PathwayBrowser/#/R-HSA-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters TAS Homo sapiens 2860 R-HSA-5625796 https://reactome.org/PathwayBrowser/#/R-HSA-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters TAS Homo sapiens 2860 R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 2860 R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 2860 R-HSA-5625849 https://reactome.org/PathwayBrowser/#/R-HSA-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters TAS Homo sapiens 2860 R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 2860 R-HSA-5625883 https://reactome.org/PathwayBrowser/#/R-HSA-5625883 PKN1 in complex with AR positively regulates expression of KLK2 and KLK3 TAS Homo sapiens 2860 R-HSA-8877902 https://reactome.org/PathwayBrowser/#/R-HSA-8877902 Activated AR binds RUNX2 TAS Homo sapiens 2860 R-HSA-8877918 https://reactome.org/PathwayBrowser/#/R-HSA-8877918 RUNX2:MAF complex binds the BGLAP gene promoter IEA Homo sapiens 2860 R-HSA-9705925 https://reactome.org/PathwayBrowser/#/R-HSA-9705925 Androgens binds AR (in the HSP90 chaperone complex) TAS Homo sapiens 2860 R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 2860 R-MMU-193064 https://reactome.org/PathwayBrowser/#/R-MMU-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Mus musculus 2860 R-MMU-193073 https://reactome.org/PathwayBrowser/#/R-MMU-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Mus musculus 2860 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 2860 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 2860 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 2860 R-MMU-5625717 https://reactome.org/PathwayBrowser/#/R-MMU-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Mus musculus 2860 R-MMU-5625738 https://reactome.org/PathwayBrowser/#/R-MMU-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Mus musculus 2860 R-MMU-5625745 https://reactome.org/PathwayBrowser/#/R-MMU-5625745 PKN1 stimulates association of AR with NCOA2 IEA Mus musculus 2860 R-MMU-8877902 https://reactome.org/PathwayBrowser/#/R-MMU-8877902 Activated AR binds RUNX2 IEA Mus musculus 2860 R-MMU-9705925 https://reactome.org/PathwayBrowser/#/R-MMU-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Mus musculus 2860 R-PFA-193064 https://reactome.org/PathwayBrowser/#/R-PFA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Plasmodium falciparum 2860 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 2860 R-PFA-9705925 https://reactome.org/PathwayBrowser/#/R-PFA-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2860 R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 2860 R-RNO-193064 https://reactome.org/PathwayBrowser/#/R-RNO-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Rattus norvegicus 2860 R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus 2860 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 2860 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 2860 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 2860 R-RNO-5625717 https://reactome.org/PathwayBrowser/#/R-RNO-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Rattus norvegicus 2860 R-RNO-5625738 https://reactome.org/PathwayBrowser/#/R-RNO-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Rattus norvegicus 2860 R-RNO-5625745 https://reactome.org/PathwayBrowser/#/R-RNO-5625745 PKN1 stimulates association of AR with NCOA2 IEA Rattus norvegicus 2860 R-RNO-5625774 https://reactome.org/PathwayBrowser/#/R-RNO-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Rattus norvegicus 2860 R-RNO-5625784 https://reactome.org/PathwayBrowser/#/R-RNO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Rattus norvegicus 2860 R-RNO-5625796 https://reactome.org/PathwayBrowser/#/R-RNO-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Rattus norvegicus 2860 R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 2860 R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 2860 R-RNO-5625849 https://reactome.org/PathwayBrowser/#/R-RNO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Rattus norvegicus 2860 R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 2860 R-RNO-9705925 https://reactome.org/PathwayBrowser/#/R-RNO-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Rattus norvegicus 2860 R-SCE-5625784 https://reactome.org/PathwayBrowser/#/R-SCE-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2860 R-SCE-5625796 https://reactome.org/PathwayBrowser/#/R-SCE-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2860 R-SCE-5625797 https://reactome.org/PathwayBrowser/#/R-SCE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2860 R-SCE-5625848 https://reactome.org/PathwayBrowser/#/R-SCE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2860 R-SCE-5625849 https://reactome.org/PathwayBrowser/#/R-SCE-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2860 R-SCE-5625870 https://reactome.org/PathwayBrowser/#/R-SCE-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Saccharomyces cerevisiae 2860 R-SPO-5625784 https://reactome.org/PathwayBrowser/#/R-SPO-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2860 R-SPO-5625848 https://reactome.org/PathwayBrowser/#/R-SPO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2860 R-SPO-5625849 https://reactome.org/PathwayBrowser/#/R-SPO-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2860 R-SPO-5625870 https://reactome.org/PathwayBrowser/#/R-SPO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Schizosaccharomyces pombe 2860 R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 2860 R-SSC-193064 https://reactome.org/PathwayBrowser/#/R-SSC-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Sus scrofa 2860 R-SSC-193073 https://reactome.org/PathwayBrowser/#/R-SSC-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Sus scrofa 2860 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 2860 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 2860 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 2860 R-SSC-5625717 https://reactome.org/PathwayBrowser/#/R-SSC-5625717 Phosphorylated PKN1 binds androgen receptor (AR) IEA Sus scrofa 2860 R-SSC-5625738 https://reactome.org/PathwayBrowser/#/R-SSC-5625738 p-T774-PKN1:AR:Androgen complex translocates to the nucleus IEA Sus scrofa 2860 R-SSC-5625745 https://reactome.org/PathwayBrowser/#/R-SSC-5625745 PKN1 stimulates association of AR with NCOA2 IEA Sus scrofa 2860 R-SSC-5625774 https://reactome.org/PathwayBrowser/#/R-SSC-5625774 PKN1:AR complex binds promoters of KLK2 and KLK3 genes IEA Sus scrofa 2860 R-SSC-5625784 https://reactome.org/PathwayBrowser/#/R-SSC-5625784 PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters IEA Sus scrofa 2860 R-SSC-5625796 https://reactome.org/PathwayBrowser/#/R-SSC-5625796 Demethylase KDM4C binds KLK2 and KLK3 promoters IEA Sus scrofa 2860 R-SSC-5625797 https://reactome.org/PathwayBrowser/#/R-SSC-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Sus scrofa 2860 R-SSC-5625848 https://reactome.org/PathwayBrowser/#/R-SSC-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 2860 R-SSC-5625849 https://reactome.org/PathwayBrowser/#/R-SSC-5625849 Demethylase KDM1A binds KLK2 and KLK3 promoters IEA Sus scrofa 2860 R-SSC-5625870 https://reactome.org/PathwayBrowser/#/R-SSC-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Sus scrofa 2860 R-SSC-8877902 https://reactome.org/PathwayBrowser/#/R-SSC-8877902 Activated AR binds RUNX2 IEA Sus scrofa 2860 R-SSC-9705925 https://reactome.org/PathwayBrowser/#/R-SSC-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Sus scrofa 2860 R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 2860 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 2860 R-XTR-8877902 https://reactome.org/PathwayBrowser/#/R-XTR-8877902 Activated AR binds RUNX2 IEA Xenopus tropicalis 2860 R-XTR-9705925 https://reactome.org/PathwayBrowser/#/R-XTR-9705925 Androgens binds AR (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2861 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 2861 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 2861 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 2861 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 2861 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 2861 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 2861 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 2861 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 2861 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 2861 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 2861 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 2863 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 2863 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 2863 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 2863 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 2863 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 2863 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 2863 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 2863 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 2863 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 2863 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 2863 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 2864 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 2864 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 2864 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 2864 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 2864 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 2864 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 2864 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 2864 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 2864 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 2864 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 2864 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 2865 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 2865 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 2865 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 2865 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 2865 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 2865 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 2865 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 2865 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 2865 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 2865 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 2865 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 2866 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 2866 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 2866 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 2866 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 2866 R-BTA-9757574 https://reactome.org/PathwayBrowser/#/R-BTA-9757574 ALB binds PREDL IEA Bos taurus 2866 R-BTA-9757686 https://reactome.org/PathwayBrowser/#/R-BTA-9757686 SERPINA6 binds PREDL IEA Bos taurus 2866 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 2866 R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 2866 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 2866 R-BTA-9759259 https://reactome.org/PathwayBrowser/#/R-BTA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Bos taurus 2866 R-BTA-9759454 https://reactome.org/PathwayBrowser/#/R-BTA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Bos taurus 2866 R-BTA-9759461 https://reactome.org/PathwayBrowser/#/R-BTA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Bos taurus 2866 R-BTA-9762343 https://reactome.org/PathwayBrowser/#/R-BTA-9762343 PREDL:ALB dissociates IEA Bos taurus 2866 R-CEL-9757686 https://reactome.org/PathwayBrowser/#/R-CEL-9757686 SERPINA6 binds PREDL IEA Caenorhabditis elegans 2866 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 2866 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 2866 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 2866 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 2866 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 2866 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 2866 R-CFA-9757574 https://reactome.org/PathwayBrowser/#/R-CFA-9757574 ALB binds PREDL IEA Canis familiaris 2866 R-CFA-9757686 https://reactome.org/PathwayBrowser/#/R-CFA-9757686 SERPINA6 binds PREDL IEA Canis familiaris 2866 R-CFA-9757706 https://reactome.org/PathwayBrowser/#/R-CFA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Canis familiaris 2866 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 2866 R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 2866 R-CFA-9759259 https://reactome.org/PathwayBrowser/#/R-CFA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Canis familiaris 2866 R-CFA-9759454 https://reactome.org/PathwayBrowser/#/R-CFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Canis familiaris 2866 R-CFA-9759461 https://reactome.org/PathwayBrowser/#/R-CFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Canis familiaris 2866 R-CFA-9762343 https://reactome.org/PathwayBrowser/#/R-CFA-9762343 PREDL:ALB dissociates IEA Canis familiaris 2866 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 2866 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 2866 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 2866 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 2866 R-DDI-9759454 https://reactome.org/PathwayBrowser/#/R-DDI-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Dictyostelium discoideum 2866 R-DDI-9759461 https://reactome.org/PathwayBrowser/#/R-DDI-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Dictyostelium discoideum 2866 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 2866 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2866 R-DME-9757686 https://reactome.org/PathwayBrowser/#/R-DME-9757686 SERPINA6 binds PREDL IEA Drosophila melanogaster 2866 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 2866 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 2866 R-DME-9759259 https://reactome.org/PathwayBrowser/#/R-DME-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Drosophila melanogaster 2866 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 2866 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 2866 R-DRE-9757686 https://reactome.org/PathwayBrowser/#/R-DRE-9757686 SERPINA6 binds PREDL IEA Danio rerio 2866 R-DRE-9757706 https://reactome.org/PathwayBrowser/#/R-DRE-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Danio rerio 2866 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 2866 R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 2866 R-DRE-9759259 https://reactome.org/PathwayBrowser/#/R-DRE-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Danio rerio 2866 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 2866 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 2866 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 2866 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 2866 R-GGA-9757574 https://reactome.org/PathwayBrowser/#/R-GGA-9757574 ALB binds PREDL IEA Gallus gallus 2866 R-GGA-9757706 https://reactome.org/PathwayBrowser/#/R-GGA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Gallus gallus 2866 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 2866 R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 2866 R-GGA-9759259 https://reactome.org/PathwayBrowser/#/R-GGA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Gallus gallus 2866 R-GGA-9759454 https://reactome.org/PathwayBrowser/#/R-GGA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Gallus gallus 2866 R-GGA-9759461 https://reactome.org/PathwayBrowser/#/R-GGA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Gallus gallus 2866 R-GGA-9762343 https://reactome.org/PathwayBrowser/#/R-GGA-9762343 PREDL:ALB dissociates IEA Gallus gallus 2866 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 2866 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 2866 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 2866 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 2866 R-HSA-9757540 https://reactome.org/PathwayBrowser/#/R-HSA-9757540 PREDN,PREDL diffuse into GI cells TAS Homo sapiens 2866 R-HSA-9757574 https://reactome.org/PathwayBrowser/#/R-HSA-9757574 ALB binds PREDL TAS Homo sapiens 2866 R-HSA-9757686 https://reactome.org/PathwayBrowser/#/R-HSA-9757686 SERPINA6 binds PREDL TAS Homo sapiens 2866 R-HSA-9757698 https://reactome.org/PathwayBrowser/#/R-HSA-9757698 PREDN,PREDL diffuse into hepatic cells TAS Homo sapiens 2866 R-HSA-9757706 https://reactome.org/PathwayBrowser/#/R-HSA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell TAS Homo sapiens 2866 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 2866 R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 2866 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 2866 R-HSA-9759259 https://reactome.org/PathwayBrowser/#/R-HSA-9759259 HSD11B2 dehydrogenates PREDL to PREDN TAS Homo sapiens 2866 R-HSA-9759445 https://reactome.org/PathwayBrowser/#/R-HSA-9759445 PREDN,PREDL diffuse into kidney cells TAS Homo sapiens 2866 R-HSA-9759454 https://reactome.org/PathwayBrowser/#/R-HSA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells TAS Homo sapiens 2866 R-HSA-9759461 https://reactome.org/PathwayBrowser/#/R-HSA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells TAS Homo sapiens 2866 R-HSA-9762343 https://reactome.org/PathwayBrowser/#/R-HSA-9762343 PREDL:ALB dissociates TAS Homo sapiens 2866 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 2866 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 2866 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 2866 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 2866 R-MMU-9757574 https://reactome.org/PathwayBrowser/#/R-MMU-9757574 ALB binds PREDL IEA Mus musculus 2866 R-MMU-9757686 https://reactome.org/PathwayBrowser/#/R-MMU-9757686 SERPINA6 binds PREDL IEA Mus musculus 2866 R-MMU-9757706 https://reactome.org/PathwayBrowser/#/R-MMU-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Mus musculus 2866 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 2866 R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 2866 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 2866 R-MMU-9759259 https://reactome.org/PathwayBrowser/#/R-MMU-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Mus musculus 2866 R-MMU-9759454 https://reactome.org/PathwayBrowser/#/R-MMU-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Mus musculus 2866 R-MMU-9759461 https://reactome.org/PathwayBrowser/#/R-MMU-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Mus musculus 2866 R-MMU-9762343 https://reactome.org/PathwayBrowser/#/R-MMU-9762343 PREDL:ALB dissociates IEA Mus musculus 2866 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 2866 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 2866 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 2866 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2866 R-PFA-9759454 https://reactome.org/PathwayBrowser/#/R-PFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Plasmodium falciparum 2866 R-PFA-9759461 https://reactome.org/PathwayBrowser/#/R-PFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Plasmodium falciparum 2866 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 2866 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 2866 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 2866 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 2866 R-RNO-9757574 https://reactome.org/PathwayBrowser/#/R-RNO-9757574 ALB binds PREDL IEA Rattus norvegicus 2866 R-RNO-9757686 https://reactome.org/PathwayBrowser/#/R-RNO-9757686 SERPINA6 binds PREDL IEA Rattus norvegicus 2866 R-RNO-9757706 https://reactome.org/PathwayBrowser/#/R-RNO-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Rattus norvegicus 2866 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 2866 R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 2866 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 2866 R-RNO-9759259 https://reactome.org/PathwayBrowser/#/R-RNO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Rattus norvegicus 2866 R-RNO-9759454 https://reactome.org/PathwayBrowser/#/R-RNO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Rattus norvegicus 2866 R-RNO-9759461 https://reactome.org/PathwayBrowser/#/R-RNO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Rattus norvegicus 2866 R-RNO-9762343 https://reactome.org/PathwayBrowser/#/R-RNO-9762343 PREDL:ALB dissociates IEA Rattus norvegicus 2866 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 2866 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 2866 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 2866 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 2866 R-SPO-9759259 https://reactome.org/PathwayBrowser/#/R-SPO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Schizosaccharomyces pombe 2866 R-SPO-9759454 https://reactome.org/PathwayBrowser/#/R-SPO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Schizosaccharomyces pombe 2866 R-SPO-9759461 https://reactome.org/PathwayBrowser/#/R-SPO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Schizosaccharomyces pombe 2866 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 2866 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 2866 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 2866 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 2866 R-SSC-9757574 https://reactome.org/PathwayBrowser/#/R-SSC-9757574 ALB binds PREDL IEA Sus scrofa 2866 R-SSC-9757686 https://reactome.org/PathwayBrowser/#/R-SSC-9757686 SERPINA6 binds PREDL IEA Sus scrofa 2866 R-SSC-9757706 https://reactome.org/PathwayBrowser/#/R-SSC-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Sus scrofa 2866 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 2866 R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 2866 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 2866 R-SSC-9759259 https://reactome.org/PathwayBrowser/#/R-SSC-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Sus scrofa 2866 R-SSC-9759454 https://reactome.org/PathwayBrowser/#/R-SSC-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Sus scrofa 2866 R-SSC-9759461 https://reactome.org/PathwayBrowser/#/R-SSC-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Sus scrofa 2866 R-SSC-9762343 https://reactome.org/PathwayBrowser/#/R-SSC-9762343 PREDL:ALB dissociates IEA Sus scrofa 2866 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 2866 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2866 R-XTR-9757574 https://reactome.org/PathwayBrowser/#/R-XTR-9757574 ALB binds PREDL IEA Xenopus tropicalis 2866 R-XTR-9757686 https://reactome.org/PathwayBrowser/#/R-XTR-9757686 SERPINA6 binds PREDL IEA Xenopus tropicalis 2866 R-XTR-9757706 https://reactome.org/PathwayBrowser/#/R-XTR-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Xenopus tropicalis 2866 R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 2866 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 2866 R-XTR-9759259 https://reactome.org/PathwayBrowser/#/R-XTR-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Xenopus tropicalis 2866 R-XTR-9762343 https://reactome.org/PathwayBrowser/#/R-XTR-9762343 PREDL:ALB dissociates IEA Xenopus tropicalis 2867 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 2867 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 2867 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 2867 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 2867 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 2867 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2867 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 2867 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 2867 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 2867 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 2867 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 2867 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 2867 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 2867 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 2867 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 2867 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2867 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 2867 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 2867 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 2867 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 2867 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 2867 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2868 R-BTA-1449687 https://reactome.org/PathwayBrowser/#/R-BTA-1449687 Corticosteroids bind to CBG in blood IEA Bos taurus 2868 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 2868 R-BTA-194023 https://reactome.org/PathwayBrowser/#/R-BTA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Bos taurus 2868 R-BTA-4341025 https://reactome.org/PathwayBrowser/#/R-BTA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Bos taurus 2868 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 2868 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 2868 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 2868 R-BTA-5618099 https://reactome.org/PathwayBrowser/#/R-BTA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Bos taurus 2868 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 2868 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 2868 R-CEL-1449687 https://reactome.org/PathwayBrowser/#/R-CEL-1449687 Corticosteroids bind to CBG in blood IEA Caenorhabditis elegans 2868 R-CFA-1449687 https://reactome.org/PathwayBrowser/#/R-CFA-1449687 Corticosteroids bind to CBG in blood IEA Canis familiaris 2868 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 2868 R-CFA-194023 https://reactome.org/PathwayBrowser/#/R-CFA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Canis familiaris 2868 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 2868 R-CFA-5618099 https://reactome.org/PathwayBrowser/#/R-CFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Canis familiaris 2868 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 2868 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 2868 R-DME-1449687 https://reactome.org/PathwayBrowser/#/R-DME-1449687 Corticosteroids bind to CBG in blood IEA Drosophila melanogaster 2868 R-DME-194023 https://reactome.org/PathwayBrowser/#/R-DME-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Drosophila melanogaster 2868 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 2868 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 2868 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 2868 R-DME-5618099 https://reactome.org/PathwayBrowser/#/R-DME-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2868 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 2868 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2868 R-DRE-1449687 https://reactome.org/PathwayBrowser/#/R-DRE-1449687 Corticosteroids bind to CBG in blood IEA Danio rerio 2868 R-DRE-194023 https://reactome.org/PathwayBrowser/#/R-DRE-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Danio rerio 2868 R-DRE-4341025 https://reactome.org/PathwayBrowser/#/R-DRE-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Danio rerio 2868 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 2868 R-DRE-5618099 https://reactome.org/PathwayBrowser/#/R-DRE-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Danio rerio 2868 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 2868 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 2868 R-GGA-194023 https://reactome.org/PathwayBrowser/#/R-GGA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Gallus gallus 2868 R-GGA-4341025 https://reactome.org/PathwayBrowser/#/R-GGA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Gallus gallus 2868 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 2868 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 2868 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 2868 R-GGA-5618099 https://reactome.org/PathwayBrowser/#/R-GGA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Gallus gallus 2868 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 2868 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 2868 R-HSA-1449687 https://reactome.org/PathwayBrowser/#/R-HSA-1449687 Corticosteroids bind to CBG in blood TAS Homo sapiens 2868 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 2868 R-HSA-194023 https://reactome.org/PathwayBrowser/#/R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR TAS Homo sapiens 2868 R-HSA-194036 https://reactome.org/PathwayBrowser/#/R-HSA-194036 Cortisol translocates from the mitochondrial matrix to the cytosol TAS Homo sapiens 2868 R-HSA-4341025 https://reactome.org/PathwayBrowser/#/R-HSA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 TAS Homo sapiens 2868 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 2868 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 2868 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 2868 R-HSA-5618099 https://reactome.org/PathwayBrowser/#/R-HSA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) TAS Homo sapiens 2868 R-HSA-8848804 https://reactome.org/PathwayBrowser/#/R-HSA-8848804 HIF1A,EPAS1 promote PTK6 gene expression TAS Homo sapiens 2868 R-HSA-8856930 https://reactome.org/PathwayBrowser/#/R-HSA-8856930 EPAS1 (HIF2A) and activated NR3C1 (GCR) bind PTK6 gene TAS Homo sapiens 2868 R-HSA-8939900 https://reactome.org/PathwayBrowser/#/R-HSA-8939900 RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 IEA Homo sapiens 2868 R-HSA-9009085 https://reactome.org/PathwayBrowser/#/R-HSA-9009085 DEXA:NR3C1 complex binds RUNX2 gene proximal promoter IEA Homo sapiens 2868 R-HSA-9625693 https://reactome.org/PathwayBrowser/#/R-HSA-9625693 TRIM63 gene expression is stimulated by FOXO1 and FOXO3 IEA Homo sapiens 2868 R-HSA-9625699 https://reactome.org/PathwayBrowser/#/R-HSA-9625699 FOXO1 and NR3C1 bind TRIM63 gene promoter IEA Homo sapiens 2868 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 2868 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 2868 R-HSA-9769345 https://reactome.org/PathwayBrowser/#/R-HSA-9769345 Activated glucocorticoid receptor represses NPAS4 gene transcription IEA Homo sapiens 2868 R-HSA-9769347 https://reactome.org/PathwayBrowser/#/R-HSA-9769347 Activated glucocorticoid receptor binds NPAS4 gene promoter IEA Homo sapiens 2868 R-MMU-1449687 https://reactome.org/PathwayBrowser/#/R-MMU-1449687 Corticosteroids bind to CBG in blood IEA Mus musculus 2868 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 2868 R-MMU-194023 https://reactome.org/PathwayBrowser/#/R-MMU-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Mus musculus 2868 R-MMU-4341025 https://reactome.org/PathwayBrowser/#/R-MMU-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Mus musculus 2868 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 2868 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 2868 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 2868 R-MMU-5618099 https://reactome.org/PathwayBrowser/#/R-MMU-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Mus musculus 2868 R-MMU-9009091 https://reactome.org/PathwayBrowser/#/R-MMU-9009091 Nr3c1:DEXA binds Runx2 proximal promoter TAS Mus musculus 2868 R-MMU-9009102 https://reactome.org/PathwayBrowser/#/R-MMU-9009102 Runx2 gene expression from proximal (P2) promoter is stimulated by Runx2-P2 and inhibited by DEXA:Nr3c1 TAS Mus musculus 2868 R-MMU-9625700 https://reactome.org/PathwayBrowser/#/R-MMU-9625700 Foxo1 and Nr3c1 bind Trim63 gene promoter TAS Mus musculus 2868 R-MMU-9625730 https://reactome.org/PathwayBrowser/#/R-MMU-9625730 Trim63 gene expression is activated by Foxo1 and Nr3c1 TAS Mus musculus 2868 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 2868 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 2868 R-MMU-9769703 https://reactome.org/PathwayBrowser/#/R-MMU-9769703 Activated glucocorticoid receptor binds Npas4 gene promoter TAS Mus musculus 2868 R-MMU-9769713 https://reactome.org/PathwayBrowser/#/R-MMU-9769713 Activated glucocorticoid receptor represses Npas4 gene transcription TAS Mus musculus 2868 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 2868 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 2868 R-PFA-5618099 https://reactome.org/PathwayBrowser/#/R-PFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2868 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 2868 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2868 R-RNO-1449687 https://reactome.org/PathwayBrowser/#/R-RNO-1449687 Corticosteroids bind to CBG in blood IEA Rattus norvegicus 2868 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 2868 R-RNO-194023 https://reactome.org/PathwayBrowser/#/R-RNO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Rattus norvegicus 2868 R-RNO-4341025 https://reactome.org/PathwayBrowser/#/R-RNO-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Rattus norvegicus 2868 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 2868 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 2868 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 2868 R-RNO-5618099 https://reactome.org/PathwayBrowser/#/R-RNO-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Rattus norvegicus 2868 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 2868 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 2868 R-SPO-194023 https://reactome.org/PathwayBrowser/#/R-SPO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Schizosaccharomyces pombe 2868 R-SSC-1449687 https://reactome.org/PathwayBrowser/#/R-SSC-1449687 Corticosteroids bind to CBG in blood IEA Sus scrofa 2868 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 2868 R-SSC-194023 https://reactome.org/PathwayBrowser/#/R-SSC-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Sus scrofa 2868 R-SSC-4341025 https://reactome.org/PathwayBrowser/#/R-SSC-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Sus scrofa 2868 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 2868 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 2868 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 2868 R-SSC-5618099 https://reactome.org/PathwayBrowser/#/R-SSC-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Sus scrofa 2868 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 2868 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 2868 R-XTR-1449687 https://reactome.org/PathwayBrowser/#/R-XTR-1449687 Corticosteroids bind to CBG in blood IEA Xenopus tropicalis 2868 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 2868 R-XTR-194023 https://reactome.org/PathwayBrowser/#/R-XTR-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Xenopus tropicalis 2868 R-XTR-4341025 https://reactome.org/PathwayBrowser/#/R-XTR-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Xenopus tropicalis 2868 R-XTR-5618099 https://reactome.org/PathwayBrowser/#/R-XTR-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2868 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 2868 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2869 R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 2869 R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 2869 R-BTA-4341025 https://reactome.org/PathwayBrowser/#/R-BTA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Bos taurus 2869 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 2869 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 2869 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 2869 R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 2869 R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 2869 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 2869 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 2869 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 2869 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 2869 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2869 R-DRE-4341025 https://reactome.org/PathwayBrowser/#/R-DRE-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Danio rerio 2869 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 2869 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 2869 R-GGA-4341025 https://reactome.org/PathwayBrowser/#/R-GGA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Gallus gallus 2869 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 2869 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 2869 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 2869 R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 2869 R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 2869 R-HSA-4341025 https://reactome.org/PathwayBrowser/#/R-HSA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 TAS Homo sapiens 2869 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 2869 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 2869 R-HSA-6785245 https://reactome.org/PathwayBrowser/#/R-HSA-6785245 Defective CYP11B2 does not oxidise CORST TAS Homo sapiens 2869 R-HSA-8848804 https://reactome.org/PathwayBrowser/#/R-HSA-8848804 HIF1A,EPAS1 promote PTK6 gene expression TAS Homo sapiens 2869 R-HSA-8856930 https://reactome.org/PathwayBrowser/#/R-HSA-8856930 EPAS1 (HIF2A) and activated NR3C1 (GCR) bind PTK6 gene TAS Homo sapiens 2869 R-HSA-8939900 https://reactome.org/PathwayBrowser/#/R-HSA-8939900 RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 IEA Homo sapiens 2869 R-HSA-9009085 https://reactome.org/PathwayBrowser/#/R-HSA-9009085 DEXA:NR3C1 complex binds RUNX2 gene proximal promoter IEA Homo sapiens 2869 R-HSA-9625693 https://reactome.org/PathwayBrowser/#/R-HSA-9625693 TRIM63 gene expression is stimulated by FOXO1 and FOXO3 IEA Homo sapiens 2869 R-HSA-9625699 https://reactome.org/PathwayBrowser/#/R-HSA-9625699 FOXO1 and NR3C1 bind TRIM63 gene promoter IEA Homo sapiens 2869 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 2869 R-HSA-9769345 https://reactome.org/PathwayBrowser/#/R-HSA-9769345 Activated glucocorticoid receptor represses NPAS4 gene transcription IEA Homo sapiens 2869 R-HSA-9769347 https://reactome.org/PathwayBrowser/#/R-HSA-9769347 Activated glucocorticoid receptor binds NPAS4 gene promoter IEA Homo sapiens 2869 R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 2869 R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 2869 R-MMU-4341025 https://reactome.org/PathwayBrowser/#/R-MMU-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Mus musculus 2869 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 2869 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 2869 R-MMU-9009091 https://reactome.org/PathwayBrowser/#/R-MMU-9009091 Nr3c1:DEXA binds Runx2 proximal promoter TAS Mus musculus 2869 R-MMU-9009102 https://reactome.org/PathwayBrowser/#/R-MMU-9009102 Runx2 gene expression from proximal (P2) promoter is stimulated by Runx2-P2 and inhibited by DEXA:Nr3c1 TAS Mus musculus 2869 R-MMU-9625700 https://reactome.org/PathwayBrowser/#/R-MMU-9625700 Foxo1 and Nr3c1 bind Trim63 gene promoter TAS Mus musculus 2869 R-MMU-9625730 https://reactome.org/PathwayBrowser/#/R-MMU-9625730 Trim63 gene expression is activated by Foxo1 and Nr3c1 TAS Mus musculus 2869 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 2869 R-MMU-9769703 https://reactome.org/PathwayBrowser/#/R-MMU-9769703 Activated glucocorticoid receptor binds Npas4 gene promoter TAS Mus musculus 2869 R-MMU-9769713 https://reactome.org/PathwayBrowser/#/R-MMU-9769713 Activated glucocorticoid receptor represses Npas4 gene transcription TAS Mus musculus 2869 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 2869 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2869 R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 2869 R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 2869 R-RNO-4341025 https://reactome.org/PathwayBrowser/#/R-RNO-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Rattus norvegicus 2869 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 2869 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 2869 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 2869 R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 2869 R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 2869 R-SSC-4341025 https://reactome.org/PathwayBrowser/#/R-SSC-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Sus scrofa 2869 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 2869 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 2869 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 2869 R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 2869 R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 2869 R-XTR-4341025 https://reactome.org/PathwayBrowser/#/R-XTR-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Xenopus tropicalis 2869 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2870 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 2870 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 2870 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 2870 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 2870 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 2870 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2870 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 2870 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 2870 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 2870 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 2870 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 2870 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 2870 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 2870 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 2870 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 2870 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2870 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 2870 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 2870 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 2870 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 2870 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 2870 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2872 R-BTA-1449687 https://reactome.org/PathwayBrowser/#/R-BTA-1449687 Corticosteroids bind to CBG in blood IEA Bos taurus 2872 R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 2872 R-BTA-4341025 https://reactome.org/PathwayBrowser/#/R-BTA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Bos taurus 2872 R-BTA-5618073 https://reactome.org/PathwayBrowser/#/R-BTA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Bos taurus 2872 R-BTA-5618080 https://reactome.org/PathwayBrowser/#/R-BTA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Bos taurus 2872 R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 2872 R-BTA-5618099 https://reactome.org/PathwayBrowser/#/R-BTA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Bos taurus 2872 R-CEL-1449687 https://reactome.org/PathwayBrowser/#/R-CEL-1449687 Corticosteroids bind to CBG in blood IEA Caenorhabditis elegans 2872 R-CFA-1449687 https://reactome.org/PathwayBrowser/#/R-CFA-1449687 Corticosteroids bind to CBG in blood IEA Canis familiaris 2872 R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 2872 R-CFA-5618080 https://reactome.org/PathwayBrowser/#/R-CFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Canis familiaris 2872 R-CFA-5618099 https://reactome.org/PathwayBrowser/#/R-CFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Canis familiaris 2872 R-DME-1449687 https://reactome.org/PathwayBrowser/#/R-DME-1449687 Corticosteroids bind to CBG in blood IEA Drosophila melanogaster 2872 R-DME-5618073 https://reactome.org/PathwayBrowser/#/R-DME-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Drosophila melanogaster 2872 R-DME-5618080 https://reactome.org/PathwayBrowser/#/R-DME-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Drosophila melanogaster 2872 R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 2872 R-DME-5618099 https://reactome.org/PathwayBrowser/#/R-DME-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 2872 R-DRE-1449687 https://reactome.org/PathwayBrowser/#/R-DRE-1449687 Corticosteroids bind to CBG in blood IEA Danio rerio 2872 R-DRE-4341025 https://reactome.org/PathwayBrowser/#/R-DRE-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Danio rerio 2872 R-DRE-5618080 https://reactome.org/PathwayBrowser/#/R-DRE-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Danio rerio 2872 R-DRE-5618099 https://reactome.org/PathwayBrowser/#/R-DRE-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Danio rerio 2872 R-GGA-4341025 https://reactome.org/PathwayBrowser/#/R-GGA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Gallus gallus 2872 R-GGA-5618073 https://reactome.org/PathwayBrowser/#/R-GGA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Gallus gallus 2872 R-GGA-5618080 https://reactome.org/PathwayBrowser/#/R-GGA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Gallus gallus 2872 R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 2872 R-GGA-5618099 https://reactome.org/PathwayBrowser/#/R-GGA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Gallus gallus 2872 R-HSA-1449687 https://reactome.org/PathwayBrowser/#/R-HSA-1449687 Corticosteroids bind to CBG in blood TAS Homo sapiens 2872 R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 2872 R-HSA-4341025 https://reactome.org/PathwayBrowser/#/R-HSA-4341025 SUMOylation of NR3C1 (GR) with SUMO1 TAS Homo sapiens 2872 R-HSA-5618073 https://reactome.org/PathwayBrowser/#/R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein TAS Homo sapiens 2872 R-HSA-5618080 https://reactome.org/PathwayBrowser/#/R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus TAS Homo sapiens 2872 R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 2872 R-HSA-5618099 https://reactome.org/PathwayBrowser/#/R-HSA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) TAS Homo sapiens 2872 R-HSA-8848804 https://reactome.org/PathwayBrowser/#/R-HSA-8848804 HIF1A,EPAS1 promote PTK6 gene expression TAS Homo sapiens 2872 R-HSA-8856930 https://reactome.org/PathwayBrowser/#/R-HSA-8856930 EPAS1 (HIF2A) and activated NR3C1 (GCR) bind PTK6 gene TAS Homo sapiens 2872 R-HSA-8939900 https://reactome.org/PathwayBrowser/#/R-HSA-8939900 RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 IEA Homo sapiens 2872 R-HSA-9009085 https://reactome.org/PathwayBrowser/#/R-HSA-9009085 DEXA:NR3C1 complex binds RUNX2 gene proximal promoter IEA Homo sapiens 2872 R-HSA-9625693 https://reactome.org/PathwayBrowser/#/R-HSA-9625693 TRIM63 gene expression is stimulated by FOXO1 and FOXO3 IEA Homo sapiens 2872 R-HSA-9625699 https://reactome.org/PathwayBrowser/#/R-HSA-9625699 FOXO1 and NR3C1 bind TRIM63 gene promoter IEA Homo sapiens 2872 R-HSA-9769345 https://reactome.org/PathwayBrowser/#/R-HSA-9769345 Activated glucocorticoid receptor represses NPAS4 gene transcription IEA Homo sapiens 2872 R-HSA-9769347 https://reactome.org/PathwayBrowser/#/R-HSA-9769347 Activated glucocorticoid receptor binds NPAS4 gene promoter IEA Homo sapiens 2872 R-MMU-1449687 https://reactome.org/PathwayBrowser/#/R-MMU-1449687 Corticosteroids bind to CBG in blood IEA Mus musculus 2872 R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 2872 R-MMU-4341025 https://reactome.org/PathwayBrowser/#/R-MMU-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Mus musculus 2872 R-MMU-5618073 https://reactome.org/PathwayBrowser/#/R-MMU-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Mus musculus 2872 R-MMU-5618080 https://reactome.org/PathwayBrowser/#/R-MMU-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Mus musculus 2872 R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 2872 R-MMU-5618099 https://reactome.org/PathwayBrowser/#/R-MMU-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Mus musculus 2872 R-MMU-9009091 https://reactome.org/PathwayBrowser/#/R-MMU-9009091 Nr3c1:DEXA binds Runx2 proximal promoter TAS Mus musculus 2872 R-MMU-9009102 https://reactome.org/PathwayBrowser/#/R-MMU-9009102 Runx2 gene expression from proximal (P2) promoter is stimulated by Runx2-P2 and inhibited by DEXA:Nr3c1 TAS Mus musculus 2872 R-MMU-9625700 https://reactome.org/PathwayBrowser/#/R-MMU-9625700 Foxo1 and Nr3c1 bind Trim63 gene promoter TAS Mus musculus 2872 R-MMU-9625730 https://reactome.org/PathwayBrowser/#/R-MMU-9625730 Trim63 gene expression is activated by Foxo1 and Nr3c1 TAS Mus musculus 2872 R-MMU-9769703 https://reactome.org/PathwayBrowser/#/R-MMU-9769703 Activated glucocorticoid receptor binds Npas4 gene promoter TAS Mus musculus 2872 R-MMU-9769713 https://reactome.org/PathwayBrowser/#/R-MMU-9769713 Activated glucocorticoid receptor represses Npas4 gene transcription TAS Mus musculus 2872 R-PFA-5618073 https://reactome.org/PathwayBrowser/#/R-PFA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Plasmodium falciparum 2872 R-PFA-5618080 https://reactome.org/PathwayBrowser/#/R-PFA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Plasmodium falciparum 2872 R-PFA-5618099 https://reactome.org/PathwayBrowser/#/R-PFA-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 2872 R-RNO-1449687 https://reactome.org/PathwayBrowser/#/R-RNO-1449687 Corticosteroids bind to CBG in blood IEA Rattus norvegicus 2872 R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 2872 R-RNO-4341025 https://reactome.org/PathwayBrowser/#/R-RNO-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Rattus norvegicus 2872 R-RNO-5618073 https://reactome.org/PathwayBrowser/#/R-RNO-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Rattus norvegicus 2872 R-RNO-5618080 https://reactome.org/PathwayBrowser/#/R-RNO-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Rattus norvegicus 2872 R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 2872 R-RNO-5618099 https://reactome.org/PathwayBrowser/#/R-RNO-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Rattus norvegicus 2872 R-SSC-1449687 https://reactome.org/PathwayBrowser/#/R-SSC-1449687 Corticosteroids bind to CBG in blood IEA Sus scrofa 2872 R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 2872 R-SSC-4341025 https://reactome.org/PathwayBrowser/#/R-SSC-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Sus scrofa 2872 R-SSC-5618073 https://reactome.org/PathwayBrowser/#/R-SSC-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein IEA Sus scrofa 2872 R-SSC-5618080 https://reactome.org/PathwayBrowser/#/R-SSC-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus IEA Sus scrofa 2872 R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 2872 R-SSC-5618099 https://reactome.org/PathwayBrowser/#/R-SSC-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Sus scrofa 2872 R-XTR-1449687 https://reactome.org/PathwayBrowser/#/R-XTR-1449687 Corticosteroids bind to CBG in blood IEA Xenopus tropicalis 2872 R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 2872 R-XTR-4341025 https://reactome.org/PathwayBrowser/#/R-XTR-4341025 SUMOylation of NR3C1 (GR) with SUMO1 IEA Xenopus tropicalis 2872 R-XTR-5618099 https://reactome.org/PathwayBrowser/#/R-XTR-5618099 NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 2873 R-BTA-9726509 https://reactome.org/PathwayBrowser/#/R-BTA-9726509 NR3C2 binds fludrocortisone IEA Bos taurus 2873 R-CFA-9726509 https://reactome.org/PathwayBrowser/#/R-CFA-9726509 NR3C2 binds fludrocortisone IEA Canis familiaris 2873 R-DME-9726509 https://reactome.org/PathwayBrowser/#/R-DME-9726509 NR3C2 binds fludrocortisone IEA Drosophila melanogaster 2873 R-DRE-9726509 https://reactome.org/PathwayBrowser/#/R-DRE-9726509 NR3C2 binds fludrocortisone IEA Danio rerio 2873 R-GGA-9726509 https://reactome.org/PathwayBrowser/#/R-GGA-9726509 NR3C2 binds fludrocortisone IEA Gallus gallus 2873 R-HSA-9726509 https://reactome.org/PathwayBrowser/#/R-HSA-9726509 NR3C2 binds fludrocortisone TAS Homo sapiens 2873 R-MMU-9726509 https://reactome.org/PathwayBrowser/#/R-MMU-9726509 NR3C2 binds fludrocortisone IEA Mus musculus 2873 R-PFA-9726509 https://reactome.org/PathwayBrowser/#/R-PFA-9726509 NR3C2 binds fludrocortisone IEA Plasmodium falciparum 2873 R-RNO-9726509 https://reactome.org/PathwayBrowser/#/R-RNO-9726509 NR3C2 binds fludrocortisone IEA Rattus norvegicus 2873 R-SSC-9726509 https://reactome.org/PathwayBrowser/#/R-SSC-9726509 NR3C2 binds fludrocortisone IEA Sus scrofa 2873 R-XTR-9726509 https://reactome.org/PathwayBrowser/#/R-XTR-9726509 NR3C2 binds fludrocortisone IEA Xenopus tropicalis 2874 R-BTA-9725855 https://reactome.org/PathwayBrowser/#/R-BTA-9725855 NR3C2 binds NR3C2 antagonists IEA Bos taurus 2874 R-CFA-9725855 https://reactome.org/PathwayBrowser/#/R-CFA-9725855 NR3C2 binds NR3C2 antagonists IEA Canis familiaris 2874 R-DME-9725855 https://reactome.org/PathwayBrowser/#/R-DME-9725855 NR3C2 binds NR3C2 antagonists IEA Drosophila melanogaster 2874 R-DRE-9725855 https://reactome.org/PathwayBrowser/#/R-DRE-9725855 NR3C2 binds NR3C2 antagonists IEA Danio rerio 2874 R-GGA-9725855 https://reactome.org/PathwayBrowser/#/R-GGA-9725855 NR3C2 binds NR3C2 antagonists IEA Gallus gallus 2874 R-HSA-9725855 https://reactome.org/PathwayBrowser/#/R-HSA-9725855 NR3C2 binds NR3C2 antagonists TAS Homo sapiens 2874 R-MMU-9725855 https://reactome.org/PathwayBrowser/#/R-MMU-9725855 NR3C2 binds NR3C2 antagonists IEA Mus musculus 2874 R-PFA-9725855 https://reactome.org/PathwayBrowser/#/R-PFA-9725855 NR3C2 binds NR3C2 antagonists IEA Plasmodium falciparum 2874 R-RNO-9725855 https://reactome.org/PathwayBrowser/#/R-RNO-9725855 NR3C2 binds NR3C2 antagonists IEA Rattus norvegicus 2874 R-SSC-9725855 https://reactome.org/PathwayBrowser/#/R-SSC-9725855 NR3C2 binds NR3C2 antagonists IEA Sus scrofa 2874 R-XTR-9725855 https://reactome.org/PathwayBrowser/#/R-XTR-9725855 NR3C2 binds NR3C2 antagonists IEA Xenopus tropicalis 2875 R-BTA-9725855 https://reactome.org/PathwayBrowser/#/R-BTA-9725855 NR3C2 binds NR3C2 antagonists IEA Bos taurus 2875 R-CFA-9725855 https://reactome.org/PathwayBrowser/#/R-CFA-9725855 NR3C2 binds NR3C2 antagonists IEA Canis familiaris 2875 R-DME-9725855 https://reactome.org/PathwayBrowser/#/R-DME-9725855 NR3C2 binds NR3C2 antagonists IEA Drosophila melanogaster 2875 R-DRE-9725855 https://reactome.org/PathwayBrowser/#/R-DRE-9725855 NR3C2 binds NR3C2 antagonists IEA Danio rerio 2875 R-GGA-9725855 https://reactome.org/PathwayBrowser/#/R-GGA-9725855 NR3C2 binds NR3C2 antagonists IEA Gallus gallus 2875 R-HSA-9725855 https://reactome.org/PathwayBrowser/#/R-HSA-9725855 NR3C2 binds NR3C2 antagonists TAS Homo sapiens 2875 R-MMU-9725855 https://reactome.org/PathwayBrowser/#/R-MMU-9725855 NR3C2 binds NR3C2 antagonists IEA Mus musculus 2875 R-PFA-9725855 https://reactome.org/PathwayBrowser/#/R-PFA-9725855 NR3C2 binds NR3C2 antagonists IEA Plasmodium falciparum 2875 R-RNO-9725855 https://reactome.org/PathwayBrowser/#/R-RNO-9725855 NR3C2 binds NR3C2 antagonists IEA Rattus norvegicus 2875 R-SSC-9725855 https://reactome.org/PathwayBrowser/#/R-SSC-9725855 NR3C2 binds NR3C2 antagonists IEA Sus scrofa 2875 R-XTR-9725855 https://reactome.org/PathwayBrowser/#/R-XTR-9725855 NR3C2 binds NR3C2 antagonists IEA Xenopus tropicalis 2876 R-BTA-9725855 https://reactome.org/PathwayBrowser/#/R-BTA-9725855 NR3C2 binds NR3C2 antagonists IEA Bos taurus 2876 R-CFA-9725855 https://reactome.org/PathwayBrowser/#/R-CFA-9725855 NR3C2 binds NR3C2 antagonists IEA Canis familiaris 2876 R-DME-9725855 https://reactome.org/PathwayBrowser/#/R-DME-9725855 NR3C2 binds NR3C2 antagonists IEA Drosophila melanogaster 2876 R-DRE-9725855 https://reactome.org/PathwayBrowser/#/R-DRE-9725855 NR3C2 binds NR3C2 antagonists IEA Danio rerio 2876 R-GGA-9725855 https://reactome.org/PathwayBrowser/#/R-GGA-9725855 NR3C2 binds NR3C2 antagonists IEA Gallus gallus 2876 R-HSA-9725855 https://reactome.org/PathwayBrowser/#/R-HSA-9725855 NR3C2 binds NR3C2 antagonists TAS Homo sapiens 2876 R-MMU-9725855 https://reactome.org/PathwayBrowser/#/R-MMU-9725855 NR3C2 binds NR3C2 antagonists IEA Mus musculus 2876 R-PFA-9725855 https://reactome.org/PathwayBrowser/#/R-PFA-9725855 NR3C2 binds NR3C2 antagonists IEA Plasmodium falciparum 2876 R-RNO-9725855 https://reactome.org/PathwayBrowser/#/R-RNO-9725855 NR3C2 binds NR3C2 antagonists IEA Rattus norvegicus 2876 R-SSC-9725855 https://reactome.org/PathwayBrowser/#/R-SSC-9725855 NR3C2 binds NR3C2 antagonists IEA Sus scrofa 2876 R-XTR-9725855 https://reactome.org/PathwayBrowser/#/R-XTR-9725855 NR3C2 binds NR3C2 antagonists IEA Xenopus tropicalis 2878 R-BTA-9726580 https://reactome.org/PathwayBrowser/#/R-BTA-9726580 PGR binds PGR agonists IEA Bos taurus 2878 R-CFA-9726580 https://reactome.org/PathwayBrowser/#/R-CFA-9726580 PGR binds PGR agonists IEA Canis familiaris 2878 R-DME-9726580 https://reactome.org/PathwayBrowser/#/R-DME-9726580 PGR binds PGR agonists IEA Drosophila melanogaster 2878 R-DRE-9726580 https://reactome.org/PathwayBrowser/#/R-DRE-9726580 PGR binds PGR agonists IEA Danio rerio 2878 R-GGA-9726580 https://reactome.org/PathwayBrowser/#/R-GGA-9726580 PGR binds PGR agonists IEA Gallus gallus 2878 R-HSA-9726580 https://reactome.org/PathwayBrowser/#/R-HSA-9726580 PGR binds PGR agonists TAS Homo sapiens 2878 R-MMU-9726580 https://reactome.org/PathwayBrowser/#/R-MMU-9726580 PGR binds PGR agonists IEA Mus musculus 2878 R-PFA-9726580 https://reactome.org/PathwayBrowser/#/R-PFA-9726580 PGR binds PGR agonists IEA Plasmodium falciparum 2878 R-RNO-9726580 https://reactome.org/PathwayBrowser/#/R-RNO-9726580 PGR binds PGR agonists IEA Rattus norvegicus 2878 R-SSC-9726580 https://reactome.org/PathwayBrowser/#/R-SSC-9726580 PGR binds PGR agonists IEA Sus scrofa 2879 R-BTA-9726580 https://reactome.org/PathwayBrowser/#/R-BTA-9726580 PGR binds PGR agonists IEA Bos taurus 2879 R-CFA-9726580 https://reactome.org/PathwayBrowser/#/R-CFA-9726580 PGR binds PGR agonists IEA Canis familiaris 2879 R-DME-9726580 https://reactome.org/PathwayBrowser/#/R-DME-9726580 PGR binds PGR agonists IEA Drosophila melanogaster 2879 R-DRE-9726580 https://reactome.org/PathwayBrowser/#/R-DRE-9726580 PGR binds PGR agonists IEA Danio rerio 2879 R-GGA-9726580 https://reactome.org/PathwayBrowser/#/R-GGA-9726580 PGR binds PGR agonists IEA Gallus gallus 2879 R-HSA-9726580 https://reactome.org/PathwayBrowser/#/R-HSA-9726580 PGR binds PGR agonists TAS Homo sapiens 2879 R-MMU-9726580 https://reactome.org/PathwayBrowser/#/R-MMU-9726580 PGR binds PGR agonists IEA Mus musculus 2879 R-PFA-9726580 https://reactome.org/PathwayBrowser/#/R-PFA-9726580 PGR binds PGR agonists IEA Plasmodium falciparum 2879 R-RNO-9726580 https://reactome.org/PathwayBrowser/#/R-RNO-9726580 PGR binds PGR agonists IEA Rattus norvegicus 2879 R-SSC-9726580 https://reactome.org/PathwayBrowser/#/R-SSC-9726580 PGR binds PGR agonists IEA Sus scrofa 2880 R-BTA-9726580 https://reactome.org/PathwayBrowser/#/R-BTA-9726580 PGR binds PGR agonists IEA Bos taurus 2880 R-CFA-9726580 https://reactome.org/PathwayBrowser/#/R-CFA-9726580 PGR binds PGR agonists IEA Canis familiaris 2880 R-DME-9726580 https://reactome.org/PathwayBrowser/#/R-DME-9726580 PGR binds PGR agonists IEA Drosophila melanogaster 2880 R-DRE-9726580 https://reactome.org/PathwayBrowser/#/R-DRE-9726580 PGR binds PGR agonists IEA Danio rerio 2880 R-GGA-9726580 https://reactome.org/PathwayBrowser/#/R-GGA-9726580 PGR binds PGR agonists IEA Gallus gallus 2880 R-HSA-9726580 https://reactome.org/PathwayBrowser/#/R-HSA-9726580 PGR binds PGR agonists TAS Homo sapiens 2880 R-MMU-9726580 https://reactome.org/PathwayBrowser/#/R-MMU-9726580 PGR binds PGR agonists IEA Mus musculus 2880 R-PFA-9726580 https://reactome.org/PathwayBrowser/#/R-PFA-9726580 PGR binds PGR agonists IEA Plasmodium falciparum 2880 R-RNO-9726580 https://reactome.org/PathwayBrowser/#/R-RNO-9726580 PGR binds PGR agonists IEA Rattus norvegicus 2880 R-SSC-9726580 https://reactome.org/PathwayBrowser/#/R-SSC-9726580 PGR binds PGR agonists IEA Sus scrofa 2881 R-BTA-9726580 https://reactome.org/PathwayBrowser/#/R-BTA-9726580 PGR binds PGR agonists IEA Bos taurus 2881 R-CFA-9726580 https://reactome.org/PathwayBrowser/#/R-CFA-9726580 PGR binds PGR agonists IEA Canis familiaris 2881 R-DME-9726580 https://reactome.org/PathwayBrowser/#/R-DME-9726580 PGR binds PGR agonists IEA Drosophila melanogaster 2881 R-DRE-9726580 https://reactome.org/PathwayBrowser/#/R-DRE-9726580 PGR binds PGR agonists IEA Danio rerio 2881 R-GGA-9726580 https://reactome.org/PathwayBrowser/#/R-GGA-9726580 PGR binds PGR agonists IEA Gallus gallus 2881 R-HSA-9726580 https://reactome.org/PathwayBrowser/#/R-HSA-9726580 PGR binds PGR agonists TAS Homo sapiens 2881 R-MMU-9726580 https://reactome.org/PathwayBrowser/#/R-MMU-9726580 PGR binds PGR agonists IEA Mus musculus 2881 R-PFA-9726580 https://reactome.org/PathwayBrowser/#/R-PFA-9726580 PGR binds PGR agonists IEA Plasmodium falciparum 2881 R-RNO-9726580 https://reactome.org/PathwayBrowser/#/R-RNO-9726580 PGR binds PGR agonists IEA Rattus norvegicus 2881 R-SSC-9726580 https://reactome.org/PathwayBrowser/#/R-SSC-9726580 PGR binds PGR agonists IEA Sus scrofa 2885 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 2885 R-BTA-8867667 https://reactome.org/PathwayBrowser/#/R-BTA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Bos taurus 2885 R-BTA-8868402 https://reactome.org/PathwayBrowser/#/R-BTA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Bos taurus 2885 R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 2885 R-CEL-8867667 https://reactome.org/PathwayBrowser/#/R-CEL-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Caenorhabditis elegans 2885 R-CEL-8868402 https://reactome.org/PathwayBrowser/#/R-CEL-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Caenorhabditis elegans 2885 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 2885 R-CFA-8867667 https://reactome.org/PathwayBrowser/#/R-CFA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Canis familiaris 2885 R-CFA-8868402 https://reactome.org/PathwayBrowser/#/R-CFA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Canis familiaris 2885 R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 2885 R-DDI-8867667 https://reactome.org/PathwayBrowser/#/R-DDI-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Dictyostelium discoideum 2885 R-DDI-8868402 https://reactome.org/PathwayBrowser/#/R-DDI-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Dictyostelium discoideum 2885 R-DME-8867667 https://reactome.org/PathwayBrowser/#/R-DME-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Drosophila melanogaster 2885 R-DME-8868402 https://reactome.org/PathwayBrowser/#/R-DME-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Drosophila melanogaster 2885 R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 2885 R-DRE-8867667 https://reactome.org/PathwayBrowser/#/R-DRE-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Danio rerio 2885 R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 2885 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 2885 R-GGA-8867667 https://reactome.org/PathwayBrowser/#/R-GGA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Gallus gallus 2885 R-GGA-8868402 https://reactome.org/PathwayBrowser/#/R-GGA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Gallus gallus 2885 R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 2885 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 2885 R-HSA-5602885 https://reactome.org/PathwayBrowser/#/R-HSA-5602885 Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL TAS Homo sapiens 2885 R-HSA-8867667 https://reactome.org/PathwayBrowser/#/R-HSA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane TAS Homo sapiens 2885 R-HSA-8868402 https://reactome.org/PathwayBrowser/#/R-HSA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane TAS Homo sapiens 2885 R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 2885 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 2885 R-MMU-8867667 https://reactome.org/PathwayBrowser/#/R-MMU-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Mus musculus 2885 R-MMU-8868402 https://reactome.org/PathwayBrowser/#/R-MMU-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Mus musculus 2885 R-PFA-8867667 https://reactome.org/PathwayBrowser/#/R-PFA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Plasmodium falciparum 2885 R-PFA-8868402 https://reactome.org/PathwayBrowser/#/R-PFA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Plasmodium falciparum 2885 R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 2885 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 2885 R-RNO-8867667 https://reactome.org/PathwayBrowser/#/R-RNO-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Rattus norvegicus 2885 R-RNO-8868402 https://reactome.org/PathwayBrowser/#/R-RNO-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Rattus norvegicus 2885 R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 2885 R-SCE-8867667 https://reactome.org/PathwayBrowser/#/R-SCE-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Saccharomyces cerevisiae 2885 R-SCE-8868402 https://reactome.org/PathwayBrowser/#/R-SCE-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Saccharomyces cerevisiae 2885 R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 2885 R-SPO-8867667 https://reactome.org/PathwayBrowser/#/R-SPO-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Schizosaccharomyces pombe 2885 R-SPO-8868402 https://reactome.org/PathwayBrowser/#/R-SPO-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Schizosaccharomyces pombe 2885 R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 2885 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 2885 R-SSC-8867667 https://reactome.org/PathwayBrowser/#/R-SSC-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Sus scrofa 2885 R-SSC-8868402 https://reactome.org/PathwayBrowser/#/R-SSC-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane IEA Sus scrofa 2885 R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 2885 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 2885 R-XTR-8867667 https://reactome.org/PathwayBrowser/#/R-XTR-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane IEA Xenopus tropicalis 2892 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 2892 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 2892 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 2892 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 2892 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 2892 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 2892 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 2892 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 2892 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 2892 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 2892 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 2892 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 2892 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 2892 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 2892 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 2892 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 2892 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 2892 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 2893 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 2893 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 2893 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 2893 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 2893 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 2893 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 2893 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 2893 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 2893 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 2893 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 2893 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 2893 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 2893 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 2893 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 2893 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 2893 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 2893 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 2893 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 2894 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 2894 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 2894 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 2894 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 2894 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 2894 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 2894 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 2894 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 2894 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 2894 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 2894 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 2894 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 2894 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 2894 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 2894 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 2894 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 2894 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 2894 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 2896 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 2896 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 2896 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 2896 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 2896 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 2896 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 2896 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 2896 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 2896 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 2896 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 2896 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 2896 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 2896 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 2896 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 2896 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 2896 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 2896 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 2896 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 2897 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 2897 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 2897 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 2897 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 2897 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 2897 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 2897 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 2897 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 2897 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 2897 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 2897 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 2897 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 2897 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 2897 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 2897 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 2897 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 2897 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 2897 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 2932 R-BTA-3296326 https://reactome.org/PathwayBrowser/#/R-BTA-3296326 HCAR1 binds LACT IEA Bos taurus 2932 R-BTA-373867 https://reactome.org/PathwayBrowser/#/R-BTA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Bos taurus 2932 R-BTA-373875 https://reactome.org/PathwayBrowser/#/R-BTA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Bos taurus 2932 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 2932 R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Bos taurus 2932 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 2932 R-BTA-561253 https://reactome.org/PathwayBrowser/#/R-BTA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Bos taurus 2932 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 2932 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 2932 R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 2932 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 2932 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 2932 R-CEL-373867 https://reactome.org/PathwayBrowser/#/R-CEL-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 2932 R-CEL-373875 https://reactome.org/PathwayBrowser/#/R-CEL-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Caenorhabditis elegans 2932 R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 2932 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 2932 R-CEL-561253 https://reactome.org/PathwayBrowser/#/R-CEL-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Caenorhabditis elegans 2932 R-CEL-6807826 https://reactome.org/PathwayBrowser/#/R-CEL-6807826 LDHAL6B reduces PYR to LACT IEA Caenorhabditis elegans 2932 R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 2932 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 2932 R-CFA-3296326 https://reactome.org/PathwayBrowser/#/R-CFA-3296326 HCAR1 binds LACT IEA Canis familiaris 2932 R-CFA-373867 https://reactome.org/PathwayBrowser/#/R-CFA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Canis familiaris 2932 R-CFA-373875 https://reactome.org/PathwayBrowser/#/R-CFA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Canis familiaris 2932 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 2932 R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Canis familiaris 2932 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 2932 R-CFA-561253 https://reactome.org/PathwayBrowser/#/R-CFA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Canis familiaris 2932 R-CFA-6807826 https://reactome.org/PathwayBrowser/#/R-CFA-6807826 LDHAL6B reduces PYR to LACT IEA Canis familiaris 2932 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 2932 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 2932 R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 2932 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 2932 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 2932 R-DME-373867 https://reactome.org/PathwayBrowser/#/R-DME-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Drosophila melanogaster 2932 R-DME-373875 https://reactome.org/PathwayBrowser/#/R-DME-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Drosophila melanogaster 2932 R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 2932 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 2932 R-DME-561253 https://reactome.org/PathwayBrowser/#/R-DME-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Drosophila melanogaster 2932 R-DME-6807826 https://reactome.org/PathwayBrowser/#/R-DME-6807826 LDHAL6B reduces PYR to LACT IEA Drosophila melanogaster 2932 R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 2932 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 2932 R-DRE-3296326 https://reactome.org/PathwayBrowser/#/R-DRE-3296326 HCAR1 binds LACT IEA Danio rerio 2932 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 2932 R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Danio rerio 2932 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 2932 R-DRE-6807826 https://reactome.org/PathwayBrowser/#/R-DRE-6807826 LDHAL6B reduces PYR to LACT IEA Danio rerio 2932 R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 2932 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 2932 R-GGA-373867 https://reactome.org/PathwayBrowser/#/R-GGA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Gallus gallus 2932 R-GGA-373875 https://reactome.org/PathwayBrowser/#/R-GGA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Gallus gallus 2932 R-GGA-373887 https://reactome.org/PathwayBrowser/#/R-GGA-373887 lactate + H+ [extracellular] <=> lactate + H+ [cytosol] IEA Gallus gallus 2932 R-GGA-373889 https://reactome.org/PathwayBrowser/#/R-GGA-373889 lactate + H+ [cytosol] <=> lactate + H+ [extracellular] IEA Gallus gallus 2932 R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Gallus gallus 2932 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 2932 R-GGA-6807826 https://reactome.org/PathwayBrowser/#/R-GGA-6807826 LDHAL6B reduces PYR to LACT IEA Gallus gallus 2932 R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 2932 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 2932 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 2932 R-HSA-3296326 https://reactome.org/PathwayBrowser/#/R-HSA-3296326 HCAR1 binds LACT TAS Homo sapiens 2932 R-HSA-373867 https://reactome.org/PathwayBrowser/#/R-HSA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol TAS Homo sapiens 2932 R-HSA-373875 https://reactome.org/PathwayBrowser/#/R-HSA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region TAS Homo sapiens 2932 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 2932 R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol TAS Homo sapiens 2932 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 2932 R-HSA-561253 https://reactome.org/PathwayBrowser/#/R-HSA-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT TAS Homo sapiens 2932 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 2932 R-HSA-6807826 https://reactome.org/PathwayBrowser/#/R-HSA-6807826 LDHAL6B reduces PYR to LACT TAS Homo sapiens 2932 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 2932 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 2932 R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 2932 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 2932 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 2932 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 2932 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 2932 R-MMU-3296326 https://reactome.org/PathwayBrowser/#/R-MMU-3296326 HCAR1 binds LACT IEA Mus musculus 2932 R-MMU-373867 https://reactome.org/PathwayBrowser/#/R-MMU-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Mus musculus 2932 R-MMU-373875 https://reactome.org/PathwayBrowser/#/R-MMU-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Mus musculus 2932 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 2932 R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Mus musculus 2932 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 2932 R-MMU-561253 https://reactome.org/PathwayBrowser/#/R-MMU-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Mus musculus 2932 R-MMU-6807826 https://reactome.org/PathwayBrowser/#/R-MMU-6807826 LDHAL6B reduces PYR to LACT IEA Mus musculus 2932 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 2932 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 2932 R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 2932 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 2932 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 2932 R-RNO-3296326 https://reactome.org/PathwayBrowser/#/R-RNO-3296326 HCAR1 binds LACT IEA Rattus norvegicus 2932 R-RNO-373867 https://reactome.org/PathwayBrowser/#/R-RNO-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Rattus norvegicus 2932 R-RNO-373875 https://reactome.org/PathwayBrowser/#/R-RNO-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Rattus norvegicus 2932 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 2932 R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Rattus norvegicus 2932 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 2932 R-RNO-561253 https://reactome.org/PathwayBrowser/#/R-RNO-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Rattus norvegicus 2932 R-RNO-6807826 https://reactome.org/PathwayBrowser/#/R-RNO-6807826 LDHAL6B reduces PYR to LACT IEA Rattus norvegicus 2932 R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 2932 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 2932 R-SSC-3296326 https://reactome.org/PathwayBrowser/#/R-SSC-3296326 HCAR1 binds LACT IEA Sus scrofa 2932 R-SSC-373867 https://reactome.org/PathwayBrowser/#/R-SSC-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Sus scrofa 2932 R-SSC-373875 https://reactome.org/PathwayBrowser/#/R-SSC-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Sus scrofa 2932 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 2932 R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Sus scrofa 2932 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 2932 R-SSC-561253 https://reactome.org/PathwayBrowser/#/R-SSC-561253 SLC22A12 exchanges extracellular urate for cytosolic LACT IEA Sus scrofa 2932 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 2932 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 2932 R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 2932 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 2932 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 2932 R-XTR-373867 https://reactome.org/PathwayBrowser/#/R-XTR-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Xenopus tropicalis 2932 R-XTR-373875 https://reactome.org/PathwayBrowser/#/R-XTR-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Xenopus tropicalis 2932 R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 2932 R-XTR-6807826 https://reactome.org/PathwayBrowser/#/R-XTR-6807826 LDHAL6B reduces PYR to LACT IEA Xenopus tropicalis 2932 R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 2932 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 294 R-BTA-264615 https://reactome.org/PathwayBrowser/#/R-BTA-264615 Loading of acetylcholine in synaptic vesicles IEA Bos taurus 294 R-BTA-264622 https://reactome.org/PathwayBrowser/#/R-BTA-264622 Cho is acetylated to AcCho by CHAT IEA Bos taurus 294 R-BTA-372505 https://reactome.org/PathwayBrowser/#/R-BTA-372505 Acetylcholine synaptic vesicle docking and priming IEA Bos taurus 294 R-BTA-372529 https://reactome.org/PathwayBrowser/#/R-BTA-372529 Release of acetylcholine at the synapse IEA Bos taurus 294 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 294 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 294 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 294 R-BTA-390649 https://reactome.org/PathwayBrowser/#/R-BTA-390649 CHRM1,3,5 bind acetylcholine IEA Bos taurus 294 R-BTA-390673 https://reactome.org/PathwayBrowser/#/R-BTA-390673 CHRM2,4 bind acetylcholine IEA Bos taurus 294 R-BTA-622325 https://reactome.org/PathwayBrowser/#/R-BTA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 294 R-BTA-622326 https://reactome.org/PathwayBrowser/#/R-BTA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Bos taurus 294 R-BTA-629588 https://reactome.org/PathwayBrowser/#/R-BTA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Bos taurus 294 R-BTA-629595 https://reactome.org/PathwayBrowser/#/R-BTA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 294 R-BTA-629596 https://reactome.org/PathwayBrowser/#/R-BTA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 294 R-BTA-629599 https://reactome.org/PathwayBrowser/#/R-BTA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Bos taurus 294 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 294 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 294 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 294 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 294 R-CEL-264615 https://reactome.org/PathwayBrowser/#/R-CEL-264615 Loading of acetylcholine in synaptic vesicles IEA Caenorhabditis elegans 294 R-CEL-264622 https://reactome.org/PathwayBrowser/#/R-CEL-264622 Cho is acetylated to AcCho by CHAT IEA Caenorhabditis elegans 294 R-CEL-372505 https://reactome.org/PathwayBrowser/#/R-CEL-372505 Acetylcholine synaptic vesicle docking and priming IEA Caenorhabditis elegans 294 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 294 R-CEL-372529 https://reactome.org/PathwayBrowser/#/R-CEL-372529 Release of acetylcholine at the synapse IEA Caenorhabditis elegans 294 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 294 R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 294 R-CEL-390649 https://reactome.org/PathwayBrowser/#/R-CEL-390649 CHRM1,3,5 bind acetylcholine IEA Caenorhabditis elegans 294 R-CEL-390673 https://reactome.org/PathwayBrowser/#/R-CEL-390673 CHRM2,4 bind acetylcholine IEA Caenorhabditis elegans 294 R-CEL-622325 https://reactome.org/PathwayBrowser/#/R-CEL-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 294 R-CEL-622326 https://reactome.org/PathwayBrowser/#/R-CEL-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Caenorhabditis elegans 294 R-CEL-629588 https://reactome.org/PathwayBrowser/#/R-CEL-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Caenorhabditis elegans 294 R-CEL-629595 https://reactome.org/PathwayBrowser/#/R-CEL-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 294 R-CEL-629596 https://reactome.org/PathwayBrowser/#/R-CEL-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 294 R-CEL-629599 https://reactome.org/PathwayBrowser/#/R-CEL-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Caenorhabditis elegans 294 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 294 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 294 R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 294 R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 294 R-CFA-264615 https://reactome.org/PathwayBrowser/#/R-CFA-264615 Loading of acetylcholine in synaptic vesicles IEA Canis familiaris 294 R-CFA-264622 https://reactome.org/PathwayBrowser/#/R-CFA-264622 Cho is acetylated to AcCho by CHAT IEA Canis familiaris 294 R-CFA-372505 https://reactome.org/PathwayBrowser/#/R-CFA-372505 Acetylcholine synaptic vesicle docking and priming IEA Canis familiaris 294 R-CFA-372529 https://reactome.org/PathwayBrowser/#/R-CFA-372529 Release of acetylcholine at the synapse IEA Canis familiaris 294 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 294 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 294 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 294 R-CFA-390649 https://reactome.org/PathwayBrowser/#/R-CFA-390649 CHRM1,3,5 bind acetylcholine IEA Canis familiaris 294 R-CFA-390673 https://reactome.org/PathwayBrowser/#/R-CFA-390673 CHRM2,4 bind acetylcholine IEA Canis familiaris 294 R-CFA-622325 https://reactome.org/PathwayBrowser/#/R-CFA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 294 R-CFA-622326 https://reactome.org/PathwayBrowser/#/R-CFA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Canis familiaris 294 R-CFA-629588 https://reactome.org/PathwayBrowser/#/R-CFA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Canis familiaris 294 R-CFA-629595 https://reactome.org/PathwayBrowser/#/R-CFA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 294 R-CFA-629596 https://reactome.org/PathwayBrowser/#/R-CFA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 294 R-CFA-629599 https://reactome.org/PathwayBrowser/#/R-CFA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Canis familiaris 294 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 294 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 294 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 294 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 294 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 294 R-DME-264615 https://reactome.org/PathwayBrowser/#/R-DME-264615 Loading of acetylcholine in synaptic vesicles IEA Drosophila melanogaster 294 R-DME-264622 https://reactome.org/PathwayBrowser/#/R-DME-264622 Cho is acetylated to AcCho by CHAT IEA Drosophila melanogaster 294 R-DME-372505 https://reactome.org/PathwayBrowser/#/R-DME-372505 Acetylcholine synaptic vesicle docking and priming IEA Drosophila melanogaster 294 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 294 R-DME-372529 https://reactome.org/PathwayBrowser/#/R-DME-372529 Release of acetylcholine at the synapse IEA Drosophila melanogaster 294 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 294 R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 294 R-DME-390649 https://reactome.org/PathwayBrowser/#/R-DME-390649 CHRM1,3,5 bind acetylcholine IEA Drosophila melanogaster 294 R-DME-390673 https://reactome.org/PathwayBrowser/#/R-DME-390673 CHRM2,4 bind acetylcholine IEA Drosophila melanogaster 294 R-DME-622325 https://reactome.org/PathwayBrowser/#/R-DME-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 294 R-DME-622326 https://reactome.org/PathwayBrowser/#/R-DME-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Drosophila melanogaster 294 R-DME-629588 https://reactome.org/PathwayBrowser/#/R-DME-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Drosophila melanogaster 294 R-DME-629595 https://reactome.org/PathwayBrowser/#/R-DME-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 294 R-DME-629596 https://reactome.org/PathwayBrowser/#/R-DME-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 294 R-DME-629599 https://reactome.org/PathwayBrowser/#/R-DME-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Drosophila melanogaster 294 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 294 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 294 R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 294 R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 294 R-DRE-264615 https://reactome.org/PathwayBrowser/#/R-DRE-264615 Loading of acetylcholine in synaptic vesicles IEA Danio rerio 294 R-DRE-264622 https://reactome.org/PathwayBrowser/#/R-DRE-264622 Cho is acetylated to AcCho by CHAT IEA Danio rerio 294 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 294 R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 294 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 294 R-DRE-390649 https://reactome.org/PathwayBrowser/#/R-DRE-390649 CHRM1,3,5 bind acetylcholine IEA Danio rerio 294 R-DRE-390673 https://reactome.org/PathwayBrowser/#/R-DRE-390673 CHRM2,4 bind acetylcholine IEA Danio rerio 294 R-DRE-622326 https://reactome.org/PathwayBrowser/#/R-DRE-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Danio rerio 294 R-DRE-629595 https://reactome.org/PathwayBrowser/#/R-DRE-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Danio rerio 294 R-DRE-629596 https://reactome.org/PathwayBrowser/#/R-DRE-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Danio rerio 294 R-DRE-629599 https://reactome.org/PathwayBrowser/#/R-DRE-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Danio rerio 294 R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus 294 R-GGA-264622 https://reactome.org/PathwayBrowser/#/R-GGA-264622 Cho is acetylated to AcCho by CHAT IEA Gallus gallus 294 R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus 294 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 294 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 294 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 294 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 294 R-GGA-390649 https://reactome.org/PathwayBrowser/#/R-GGA-390649 CHRM1,3,5 bind acetylcholine IEA Gallus gallus 294 R-GGA-390673 https://reactome.org/PathwayBrowser/#/R-GGA-390673 CHRM2,4 bind acetylcholine IEA Gallus gallus 294 R-GGA-622325 https://reactome.org/PathwayBrowser/#/R-GGA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 294 R-GGA-622326 https://reactome.org/PathwayBrowser/#/R-GGA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Gallus gallus 294 R-GGA-629588 https://reactome.org/PathwayBrowser/#/R-GGA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Gallus gallus 294 R-GGA-629595 https://reactome.org/PathwayBrowser/#/R-GGA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 294 R-GGA-629596 https://reactome.org/PathwayBrowser/#/R-GGA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 294 R-GGA-629599 https://reactome.org/PathwayBrowser/#/R-GGA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Gallus gallus 294 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 294 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 294 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 294 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 294 R-HSA-264615 https://reactome.org/PathwayBrowser/#/R-HSA-264615 Loading of acetylcholine in synaptic vesicles TAS Homo sapiens 294 R-HSA-264622 https://reactome.org/PathwayBrowser/#/R-HSA-264622 Cho is acetylated to AcCho by CHAT TAS Homo sapiens 294 R-HSA-372505 https://reactome.org/PathwayBrowser/#/R-HSA-372505 Acetylcholine synaptic vesicle docking and priming TAS Homo sapiens 294 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 294 R-HSA-372529 https://reactome.org/PathwayBrowser/#/R-HSA-372529 Release of acetylcholine at the synapse TAS Homo sapiens 294 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 294 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 294 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 294 R-HSA-390649 https://reactome.org/PathwayBrowser/#/R-HSA-390649 CHRM1,3,5 bind acetylcholine TAS Homo sapiens 294 R-HSA-390673 https://reactome.org/PathwayBrowser/#/R-HSA-390673 CHRM2,4 bind acetylcholine TAS Homo sapiens 294 R-HSA-399995 https://reactome.org/PathwayBrowser/#/R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq IEA Homo sapiens 294 R-HSA-400012 https://reactome.org/PathwayBrowser/#/R-HSA-400012 Acetylcholine binds Muscarinic Acetylcholine Receptor M3 IEA Homo sapiens 294 R-HSA-622325 https://reactome.org/PathwayBrowser/#/R-HSA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 294 R-HSA-622326 https://reactome.org/PathwayBrowser/#/R-HSA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors TAS Homo sapiens 294 R-HSA-629588 https://reactome.org/PathwayBrowser/#/R-HSA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors TAS Homo sapiens 294 R-HSA-629595 https://reactome.org/PathwayBrowser/#/R-HSA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 294 R-HSA-629596 https://reactome.org/PathwayBrowser/#/R-HSA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 294 R-HSA-629599 https://reactome.org/PathwayBrowser/#/R-HSA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors TAS Homo sapiens 294 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 294 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 294 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 294 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 294 R-HSA-9663736 https://reactome.org/PathwayBrowser/#/R-HSA-9663736 CHRNA9:CHRNA10 binds acetylcholine IEA Homo sapiens 294 R-HSA-9663785 https://reactome.org/PathwayBrowser/#/R-HSA-9663785 CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol IEA Homo sapiens 294 R-MMU-264615 https://reactome.org/PathwayBrowser/#/R-MMU-264615 Loading of acetylcholine in synaptic vesicles IEA Mus musculus 294 R-MMU-264622 https://reactome.org/PathwayBrowser/#/R-MMU-264622 Cho is acetylated to AcCho by CHAT IEA Mus musculus 294 R-MMU-372505 https://reactome.org/PathwayBrowser/#/R-MMU-372505 Acetylcholine synaptic vesicle docking and priming IEA Mus musculus 294 R-MMU-372529 https://reactome.org/PathwayBrowser/#/R-MMU-372529 Release of acetylcholine at the synapse IEA Mus musculus 294 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 294 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 294 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 294 R-MMU-390649 https://reactome.org/PathwayBrowser/#/R-MMU-390649 CHRM1,3,5 bind acetylcholine IEA Mus musculus 294 R-MMU-390673 https://reactome.org/PathwayBrowser/#/R-MMU-390673 CHRM2,4 bind acetylcholine IEA Mus musculus 294 R-MMU-426547 https://reactome.org/PathwayBrowser/#/R-MMU-426547 Activation of Gq by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 294 R-MMU-426560 https://reactome.org/PathwayBrowser/#/R-MMU-426560 Binding of Acetylcholine by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 294 R-MMU-622325 https://reactome.org/PathwayBrowser/#/R-MMU-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 294 R-MMU-622326 https://reactome.org/PathwayBrowser/#/R-MMU-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Mus musculus 294 R-MMU-629588 https://reactome.org/PathwayBrowser/#/R-MMU-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Mus musculus 294 R-MMU-629595 https://reactome.org/PathwayBrowser/#/R-MMU-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 294 R-MMU-629596 https://reactome.org/PathwayBrowser/#/R-MMU-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 294 R-MMU-629599 https://reactome.org/PathwayBrowser/#/R-MMU-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Mus musculus 294 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 294 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 294 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 294 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 294 R-RNO-264615 https://reactome.org/PathwayBrowser/#/R-RNO-264615 Loading of acetylcholine in synaptic vesicles IEA Rattus norvegicus 294 R-RNO-264622 https://reactome.org/PathwayBrowser/#/R-RNO-264622 Cho is acetylated to AcCho by CHAT IEA Rattus norvegicus 294 R-RNO-372505 https://reactome.org/PathwayBrowser/#/R-RNO-372505 Acetylcholine synaptic vesicle docking and priming IEA Rattus norvegicus 294 R-RNO-372529 https://reactome.org/PathwayBrowser/#/R-RNO-372529 Release of acetylcholine at the synapse IEA Rattus norvegicus 294 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 294 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 294 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 294 R-RNO-390649 https://reactome.org/PathwayBrowser/#/R-RNO-390649 CHRM1,3,5 bind acetylcholine IEA Rattus norvegicus 294 R-RNO-390673 https://reactome.org/PathwayBrowser/#/R-RNO-390673 CHRM2,4 bind acetylcholine IEA Rattus norvegicus 294 R-RNO-622325 https://reactome.org/PathwayBrowser/#/R-RNO-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 294 R-RNO-622326 https://reactome.org/PathwayBrowser/#/R-RNO-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Rattus norvegicus 294 R-RNO-629588 https://reactome.org/PathwayBrowser/#/R-RNO-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Rattus norvegicus 294 R-RNO-629595 https://reactome.org/PathwayBrowser/#/R-RNO-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 294 R-RNO-629596 https://reactome.org/PathwayBrowser/#/R-RNO-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 294 R-RNO-629599 https://reactome.org/PathwayBrowser/#/R-RNO-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Rattus norvegicus 294 R-RNO-9667850 https://reactome.org/PathwayBrowser/#/R-RNO-9667850 Chrna9:Chrna10:AcCho transports calcium ions from the extracellular region to the cytosol TAS Rattus norvegicus 294 R-RNO-9667857 https://reactome.org/PathwayBrowser/#/R-RNO-9667857 Chrna9:Chrna10 binds acetylcholine (AcCho) TAS Rattus norvegicus 294 R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa 294 R-SSC-264622 https://reactome.org/PathwayBrowser/#/R-SSC-264622 Cho is acetylated to AcCho by CHAT IEA Sus scrofa 294 R-SSC-372505 https://reactome.org/PathwayBrowser/#/R-SSC-372505 Acetylcholine synaptic vesicle docking and priming IEA Sus scrofa 294 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 294 R-SSC-372529 https://reactome.org/PathwayBrowser/#/R-SSC-372529 Release of acetylcholine at the synapse IEA Sus scrofa 294 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 294 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 294 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 294 R-SSC-390649 https://reactome.org/PathwayBrowser/#/R-SSC-390649 CHRM1,3,5 bind acetylcholine IEA Sus scrofa 294 R-SSC-390673 https://reactome.org/PathwayBrowser/#/R-SSC-390673 CHRM2,4 bind acetylcholine IEA Sus scrofa 294 R-SSC-622326 https://reactome.org/PathwayBrowser/#/R-SSC-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Sus scrofa 294 R-SSC-629595 https://reactome.org/PathwayBrowser/#/R-SSC-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa 294 R-SSC-629596 https://reactome.org/PathwayBrowser/#/R-SSC-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa 294 R-SSC-629599 https://reactome.org/PathwayBrowser/#/R-SSC-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Sus scrofa 294 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 294 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 294 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 294 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 294 R-XTR-264615 https://reactome.org/PathwayBrowser/#/R-XTR-264615 Loading of acetylcholine in synaptic vesicles IEA Xenopus tropicalis 294 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 294 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 294 R-XTR-383313 https://reactome.org/PathwayBrowser/#/R-XTR-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Xenopus tropicalis 294 R-XTR-390649 https://reactome.org/PathwayBrowser/#/R-XTR-390649 CHRM1,3,5 bind acetylcholine IEA Xenopus tropicalis 294 R-XTR-390673 https://reactome.org/PathwayBrowser/#/R-XTR-390673 CHRM2,4 bind acetylcholine IEA Xenopus tropicalis 294 R-XTR-622325 https://reactome.org/PathwayBrowser/#/R-XTR-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 294 R-XTR-622326 https://reactome.org/PathwayBrowser/#/R-XTR-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Xenopus tropicalis 294 R-XTR-629588 https://reactome.org/PathwayBrowser/#/R-XTR-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Xenopus tropicalis 294 R-XTR-629595 https://reactome.org/PathwayBrowser/#/R-XTR-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 294 R-XTR-629596 https://reactome.org/PathwayBrowser/#/R-XTR-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 294 R-XTR-629599 https://reactome.org/PathwayBrowser/#/R-XTR-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Xenopus tropicalis 294 R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 294 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 294 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 294 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 2949 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 2949 R-BTA-9756156 https://reactome.org/PathwayBrowser/#/R-BTA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Bos taurus 2949 R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 2949 R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 2949 R-BTA-9756177 https://reactome.org/PathwayBrowser/#/R-BTA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Bos taurus 2949 R-BTA-9757010 https://reactome.org/PathwayBrowser/#/R-BTA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Bos taurus 2949 R-BTA-9757139 https://reactome.org/PathwayBrowser/#/R-BTA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Bos taurus 2949 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 2949 R-CEL-9756177 https://reactome.org/PathwayBrowser/#/R-CEL-9756177 PON1,3 hydrolyse ATVL to ATV IEA Caenorhabditis elegans 2949 R-CEL-9757010 https://reactome.org/PathwayBrowser/#/R-CEL-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Caenorhabditis elegans 2949 R-CEL-9757139 https://reactome.org/PathwayBrowser/#/R-CEL-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Caenorhabditis elegans 2949 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 2949 R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 2949 R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 2949 R-CFA-9756177 https://reactome.org/PathwayBrowser/#/R-CFA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Canis familiaris 2949 R-CFA-9757010 https://reactome.org/PathwayBrowser/#/R-CFA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Canis familiaris 2949 R-CFA-9757139 https://reactome.org/PathwayBrowser/#/R-CFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Canis familiaris 2949 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 2949 R-DDI-9756156 https://reactome.org/PathwayBrowser/#/R-DDI-9756156 UGT1A3 lactonizes ATV to ATVL IEA Dictyostelium discoideum 2949 R-DDI-9757139 https://reactome.org/PathwayBrowser/#/R-DDI-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Dictyostelium discoideum 2949 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 2949 R-DME-9757010 https://reactome.org/PathwayBrowser/#/R-DME-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Drosophila melanogaster 2949 R-DME-9757139 https://reactome.org/PathwayBrowser/#/R-DME-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Drosophila melanogaster 2949 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 2949 R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 2949 R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 2949 R-DRE-9756177 https://reactome.org/PathwayBrowser/#/R-DRE-9756177 PON1,3 hydrolyse ATVL to ATV IEA Danio rerio 2949 R-DRE-9757010 https://reactome.org/PathwayBrowser/#/R-DRE-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Danio rerio 2949 R-DRE-9757139 https://reactome.org/PathwayBrowser/#/R-DRE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Danio rerio 2949 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 2949 R-GGA-9756156 https://reactome.org/PathwayBrowser/#/R-GGA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Gallus gallus 2949 R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 2949 R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 2949 R-GGA-9756177 https://reactome.org/PathwayBrowser/#/R-GGA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Gallus gallus 2949 R-GGA-9757010 https://reactome.org/PathwayBrowser/#/R-GGA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Gallus gallus 2949 R-GGA-9757139 https://reactome.org/PathwayBrowser/#/R-GGA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Gallus gallus 2949 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 2949 R-HSA-9756156 https://reactome.org/PathwayBrowser/#/R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL TAS Homo sapiens 2949 R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 2949 R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 2949 R-HSA-9756177 https://reactome.org/PathwayBrowser/#/R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV TAS Homo sapiens 2949 R-HSA-9757010 https://reactome.org/PathwayBrowser/#/R-HSA-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol TAS Homo sapiens 2949 R-HSA-9757139 https://reactome.org/PathwayBrowser/#/R-HSA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region TAS Homo sapiens 2949 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 2949 R-MMU-9756156 https://reactome.org/PathwayBrowser/#/R-MMU-9756156 UGT1A3 lactonizes ATV to ATVL IEA Mus musculus 2949 R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 2949 R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 2949 R-MMU-9756177 https://reactome.org/PathwayBrowser/#/R-MMU-9756177 PON1,3 hydrolyse ATVL to ATV IEA Mus musculus 2949 R-MMU-9757010 https://reactome.org/PathwayBrowser/#/R-MMU-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Mus musculus 2949 R-MMU-9757139 https://reactome.org/PathwayBrowser/#/R-MMU-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Mus musculus 2949 R-PFA-9757139 https://reactome.org/PathwayBrowser/#/R-PFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Plasmodium falciparum 2949 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 2949 R-RNO-9756156 https://reactome.org/PathwayBrowser/#/R-RNO-9756156 UGT1A3 lactonizes ATV to ATVL IEA Rattus norvegicus 2949 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 2949 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 2949 R-RNO-9756177 https://reactome.org/PathwayBrowser/#/R-RNO-9756177 PON1,3 hydrolyse ATVL to ATV IEA Rattus norvegicus 2949 R-RNO-9757010 https://reactome.org/PathwayBrowser/#/R-RNO-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Rattus norvegicus 2949 R-RNO-9757139 https://reactome.org/PathwayBrowser/#/R-RNO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Rattus norvegicus 2949 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 2949 R-SCE-9757139 https://reactome.org/PathwayBrowser/#/R-SCE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Saccharomyces cerevisiae 2949 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 2949 R-SPO-9757139 https://reactome.org/PathwayBrowser/#/R-SPO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Schizosaccharomyces pombe 2949 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 2949 R-SSC-9756156 https://reactome.org/PathwayBrowser/#/R-SSC-9756156 UGT1A3 lactonizes ATV to ATVL IEA Sus scrofa 2949 R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 2949 R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 2949 R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa 2949 R-SSC-9757010 https://reactome.org/PathwayBrowser/#/R-SSC-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Sus scrofa 2949 R-SSC-9757139 https://reactome.org/PathwayBrowser/#/R-SSC-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Sus scrofa 2949 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 2949 R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 2949 R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 2949 R-XTR-9756177 https://reactome.org/PathwayBrowser/#/R-XTR-9756177 PON1,3 hydrolyse ATVL to ATV IEA Xenopus tropicalis 2949 R-XTR-9757010 https://reactome.org/PathwayBrowser/#/R-XTR-9757010 SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol IEA Xenopus tropicalis 2949 R-XTR-9757139 https://reactome.org/PathwayBrowser/#/R-XTR-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Xenopus tropicalis 2950 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 2950 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 2950 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 2950 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 2950 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 2950 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 2950 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 2950 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 2950 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 2950 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 2950 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 2950 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 2950 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 2950 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 2951 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 2951 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 2951 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 2951 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 2951 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 2951 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 2951 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 2951 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 2951 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 2951 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 2951 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 2951 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 2951 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 2951 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 2953 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 2953 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 2953 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 2953 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 2953 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 2953 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 2953 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 2953 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 2953 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 2953 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 2953 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 2953 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 2953 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 2953 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 2954 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 2954 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 2954 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 2954 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 2954 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 2954 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 2954 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 2954 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 2954 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 2954 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 2954 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 2954 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 2954 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 2954 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 2955 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 2955 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 2955 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 2955 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 2955 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 2955 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 2955 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 2955 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 2955 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 2955 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 2955 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 2955 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 2955 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 2955 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 2957 R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 2957 R-BTA-9756156 https://reactome.org/PathwayBrowser/#/R-BTA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Bos taurus 2957 R-BTA-9756177 https://reactome.org/PathwayBrowser/#/R-BTA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Bos taurus 2957 R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 2957 R-BTA-9757139 https://reactome.org/PathwayBrowser/#/R-BTA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Bos taurus 2957 R-CEL-9756177 https://reactome.org/PathwayBrowser/#/R-CEL-9756177 PON1,3 hydrolyse ATVL to ATV IEA Caenorhabditis elegans 2957 R-CEL-9757139 https://reactome.org/PathwayBrowser/#/R-CEL-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Caenorhabditis elegans 2957 R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 2957 R-CFA-9756177 https://reactome.org/PathwayBrowser/#/R-CFA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Canis familiaris 2957 R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 2957 R-CFA-9757139 https://reactome.org/PathwayBrowser/#/R-CFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Canis familiaris 2957 R-DDI-9756156 https://reactome.org/PathwayBrowser/#/R-DDI-9756156 UGT1A3 lactonizes ATV to ATVL IEA Dictyostelium discoideum 2957 R-DDI-9757139 https://reactome.org/PathwayBrowser/#/R-DDI-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Dictyostelium discoideum 2957 R-DME-9757139 https://reactome.org/PathwayBrowser/#/R-DME-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Drosophila melanogaster 2957 R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 2957 R-DRE-9756177 https://reactome.org/PathwayBrowser/#/R-DRE-9756177 PON1,3 hydrolyse ATVL to ATV IEA Danio rerio 2957 R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 2957 R-DRE-9757139 https://reactome.org/PathwayBrowser/#/R-DRE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Danio rerio 2957 R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 2957 R-GGA-9756156 https://reactome.org/PathwayBrowser/#/R-GGA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Gallus gallus 2957 R-GGA-9756177 https://reactome.org/PathwayBrowser/#/R-GGA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Gallus gallus 2957 R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 2957 R-GGA-9757139 https://reactome.org/PathwayBrowser/#/R-GGA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Gallus gallus 2957 R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 2957 R-HSA-9756156 https://reactome.org/PathwayBrowser/#/R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL TAS Homo sapiens 2957 R-HSA-9756177 https://reactome.org/PathwayBrowser/#/R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV TAS Homo sapiens 2957 R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 2957 R-HSA-9757139 https://reactome.org/PathwayBrowser/#/R-HSA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region TAS Homo sapiens 2957 R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 2957 R-MMU-9756156 https://reactome.org/PathwayBrowser/#/R-MMU-9756156 UGT1A3 lactonizes ATV to ATVL IEA Mus musculus 2957 R-MMU-9756177 https://reactome.org/PathwayBrowser/#/R-MMU-9756177 PON1,3 hydrolyse ATVL to ATV IEA Mus musculus 2957 R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 2957 R-MMU-9757139 https://reactome.org/PathwayBrowser/#/R-MMU-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Mus musculus 2957 R-PFA-9757139 https://reactome.org/PathwayBrowser/#/R-PFA-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Plasmodium falciparum 2957 R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 2957 R-RNO-9756156 https://reactome.org/PathwayBrowser/#/R-RNO-9756156 UGT1A3 lactonizes ATV to ATVL IEA Rattus norvegicus 2957 R-RNO-9756177 https://reactome.org/PathwayBrowser/#/R-RNO-9756177 PON1,3 hydrolyse ATVL to ATV IEA Rattus norvegicus 2957 R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 2957 R-RNO-9757139 https://reactome.org/PathwayBrowser/#/R-RNO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Rattus norvegicus 2957 R-SCE-9757139 https://reactome.org/PathwayBrowser/#/R-SCE-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Saccharomyces cerevisiae 2957 R-SPO-9757139 https://reactome.org/PathwayBrowser/#/R-SPO-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Schizosaccharomyces pombe 2957 R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 2957 R-SSC-9756156 https://reactome.org/PathwayBrowser/#/R-SSC-9756156 UGT1A3 lactonizes ATV to ATVL IEA Sus scrofa 2957 R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa 2957 R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 2957 R-SSC-9757139 https://reactome.org/PathwayBrowser/#/R-SSC-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Sus scrofa 2957 R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 2957 R-XTR-9756177 https://reactome.org/PathwayBrowser/#/R-XTR-9756177 PON1,3 hydrolyse ATVL to ATV IEA Xenopus tropicalis 2957 R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 2957 R-XTR-9757139 https://reactome.org/PathwayBrowser/#/R-XTR-9757139 ABCB1,ABCC2 transport ATVs from cytosol to extracellular region IEA Xenopus tropicalis 2960 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 2960 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 2960 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 2960 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 2960 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 2960 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 2960 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 2960 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 2960 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 2960 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 2960 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 2960 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 2960 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 2960 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 3035 R-BTA-9705584 https://reactome.org/PathwayBrowser/#/R-BTA-9705584 HMGCR dimer binds statins IEA Bos taurus 3035 R-CEL-9705584 https://reactome.org/PathwayBrowser/#/R-CEL-9705584 HMGCR dimer binds statins IEA Caenorhabditis elegans 3035 R-CFA-9705584 https://reactome.org/PathwayBrowser/#/R-CFA-9705584 HMGCR dimer binds statins IEA Canis familiaris 3035 R-DDI-9705584 https://reactome.org/PathwayBrowser/#/R-DDI-9705584 HMGCR dimer binds statins IEA Dictyostelium discoideum 3035 R-DME-9705584 https://reactome.org/PathwayBrowser/#/R-DME-9705584 HMGCR dimer binds statins IEA Drosophila melanogaster 3035 R-DRE-9705584 https://reactome.org/PathwayBrowser/#/R-DRE-9705584 HMGCR dimer binds statins IEA Danio rerio 3035 R-GGA-9705584 https://reactome.org/PathwayBrowser/#/R-GGA-9705584 HMGCR dimer binds statins IEA Gallus gallus 3035 R-HSA-9705584 https://reactome.org/PathwayBrowser/#/R-HSA-9705584 HMGCR dimer binds statins TAS Homo sapiens 3035 R-MMU-9705584 https://reactome.org/PathwayBrowser/#/R-MMU-9705584 HMGCR dimer binds statins IEA Mus musculus 3035 R-RNO-9705584 https://reactome.org/PathwayBrowser/#/R-RNO-9705584 HMGCR dimer binds statins IEA Rattus norvegicus 3035 R-SCE-9705584 https://reactome.org/PathwayBrowser/#/R-SCE-9705584 HMGCR dimer binds statins IEA Saccharomyces cerevisiae 3035 R-SPO-9705584 https://reactome.org/PathwayBrowser/#/R-SPO-9705584 HMGCR dimer binds statins IEA Schizosaccharomyces pombe 3035 R-SSC-9705584 https://reactome.org/PathwayBrowser/#/R-SSC-9705584 HMGCR dimer binds statins IEA Sus scrofa 3035 R-XTR-9705584 https://reactome.org/PathwayBrowser/#/R-XTR-9705584 HMGCR dimer binds statins IEA Xenopus tropicalis 3040 R-BTA-73918 https://reactome.org/PathwayBrowser/#/R-BTA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Bos taurus 3040 R-BTA-74180 https://reactome.org/PathwayBrowser/#/R-BTA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Bos taurus 3040 R-CEL-73918 https://reactome.org/PathwayBrowser/#/R-CEL-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Caenorhabditis elegans 3040 R-CEL-74180 https://reactome.org/PathwayBrowser/#/R-CEL-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Caenorhabditis elegans 3040 R-CFA-73918 https://reactome.org/PathwayBrowser/#/R-CFA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Canis familiaris 3040 R-CFA-74180 https://reactome.org/PathwayBrowser/#/R-CFA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Canis familiaris 3040 R-DDI-73918 https://reactome.org/PathwayBrowser/#/R-DDI-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Dictyostelium discoideum 3040 R-DDI-74180 https://reactome.org/PathwayBrowser/#/R-DDI-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Dictyostelium discoideum 3040 R-DME-73918 https://reactome.org/PathwayBrowser/#/R-DME-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Drosophila melanogaster 3040 R-DME-74180 https://reactome.org/PathwayBrowser/#/R-DME-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Drosophila melanogaster 3040 R-DRE-74180 https://reactome.org/PathwayBrowser/#/R-DRE-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Danio rerio 3040 R-GGA-73918 https://reactome.org/PathwayBrowser/#/R-GGA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Gallus gallus 3040 R-GGA-74180 https://reactome.org/PathwayBrowser/#/R-GGA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Gallus gallus 3040 R-HSA-73918 https://reactome.org/PathwayBrowser/#/R-HSA-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH TAS Homo sapiens 3040 R-HSA-74180 https://reactome.org/PathwayBrowser/#/R-HSA-74180 HMG CoA => acetoacetic acid + acetyl CoA TAS Homo sapiens 3040 R-MMU-73918 https://reactome.org/PathwayBrowser/#/R-MMU-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Mus musculus 3040 R-MMU-74180 https://reactome.org/PathwayBrowser/#/R-MMU-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Mus musculus 3040 R-RNO-73918 https://reactome.org/PathwayBrowser/#/R-RNO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Rattus norvegicus 3040 R-RNO-74180 https://reactome.org/PathwayBrowser/#/R-RNO-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Rattus norvegicus 3040 R-SCE-73918 https://reactome.org/PathwayBrowser/#/R-SCE-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Saccharomyces cerevisiae 3040 R-SPO-73918 https://reactome.org/PathwayBrowser/#/R-SPO-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Schizosaccharomyces pombe 3040 R-SSC-73918 https://reactome.org/PathwayBrowser/#/R-SSC-73918 acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH IEA Sus scrofa 3040 R-SSC-74180 https://reactome.org/PathwayBrowser/#/R-SSC-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Sus scrofa 3040 R-XTR-74180 https://reactome.org/PathwayBrowser/#/R-XTR-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Xenopus tropicalis 3041 R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 3041 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 3041 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 3041 R-BTA-194674 https://reactome.org/PathwayBrowser/#/R-BTA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Bos taurus 3041 R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 3041 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 3041 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 3041 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 3041 R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 3041 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 3041 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 3041 R-BTA-209960 https://reactome.org/PathwayBrowser/#/R-BTA-209960 Diiodinated tyrosine can be deiodinated IEA Bos taurus 3041 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 3041 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 3041 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 3041 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 3041 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 3041 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 3041 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 3041 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 3041 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 3041 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 3041 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 3041 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 3041 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 3041 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 3041 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 3041 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 3041 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 3041 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 3041 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 3041 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 3041 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 3041 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 3041 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Bos taurus 3041 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 3041 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 3041 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 3041 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 3041 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 3041 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 3041 R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1 reduces O2 to H2O2 IEA Bos taurus 3041 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 3041 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 3041 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 3041 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 3041 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 3041 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 3041 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 3041 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 3041 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 3041 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 3041 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 3041 R-BTA-9915992 https://reactome.org/PathwayBrowser/#/R-BTA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Bos taurus 3041 R-BTA-9915993 https://reactome.org/PathwayBrowser/#/R-BTA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Bos taurus 3041 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 3041 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 3041 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 3041 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 3041 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 3041 R-CEL-209960 https://reactome.org/PathwayBrowser/#/R-CEL-209960 Diiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 3041 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 3041 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 3041 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 3041 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 3041 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 3041 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 3041 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 3041 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 3041 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 3041 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 3041 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 3041 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 3041 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 3041 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 3041 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 3041 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 3041 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 3041 R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1 reduces O2 to H2O2 IEA Caenorhabditis elegans 3041 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 3041 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 3041 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 3041 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 3041 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 3041 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 3041 R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 3041 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 3041 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 3041 R-CFA-194674 https://reactome.org/PathwayBrowser/#/R-CFA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Canis familiaris 3041 R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 3041 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 3041 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 3041 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 3041 R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 3041 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 3041 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 3041 R-CFA-209960 https://reactome.org/PathwayBrowser/#/R-CFA-209960 Diiodinated tyrosine can be deiodinated IEA Canis familiaris 3041 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 3041 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 3041 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 3041 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 3041 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 3041 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 3041 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 3041 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 3041 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 3041 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 3041 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 3041 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 3041 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 3041 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 3041 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 3041 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 3041 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 3041 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 3041 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Canis familiaris 3041 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 3041 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 3041 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 3041 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 3041 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 3041 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 3041 R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1 reduces O2 to H2O2 IEA Canis familiaris 3041 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 3041 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 3041 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 3041 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 3041 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 3041 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 3041 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 3041 R-CFA-9915992 https://reactome.org/PathwayBrowser/#/R-CFA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Canis familiaris 3041 R-CFA-9915993 https://reactome.org/PathwayBrowser/#/R-CFA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Canis familiaris 3041 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 3041 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 3041 R-DDI-194674 https://reactome.org/PathwayBrowser/#/R-DDI-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Dictyostelium discoideum 3041 R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 3041 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 3041 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 3041 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 3041 R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 3041 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 3041 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 3041 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 3041 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 3041 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 3041 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 3041 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 3041 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 3041 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 3041 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 3041 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 3041 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 3041 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 3041 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 3041 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 3041 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 3041 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 3041 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 3041 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 3041 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 3041 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 3041 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 3041 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 3041 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 3041 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 3041 R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 3041 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 3041 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 3041 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 3041 R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 3041 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 3041 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 3041 R-DME-209960 https://reactome.org/PathwayBrowser/#/R-DME-209960 Diiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 3041 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 3041 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 3041 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 3041 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 3041 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 3041 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 3041 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 3041 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 3041 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 3041 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 3041 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 3041 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 3041 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 3041 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 3041 R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1 reduces O2 to H2O2 IEA Drosophila melanogaster 3041 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 3041 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 3041 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 3041 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 3041 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 3041 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 3041 R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 3041 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 3041 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 3041 R-DRE-194674 https://reactome.org/PathwayBrowser/#/R-DRE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Danio rerio 3041 R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 3041 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 3041 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 3041 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 3041 R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 3041 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 3041 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 3041 R-DRE-209960 https://reactome.org/PathwayBrowser/#/R-DRE-209960 Diiodinated tyrosine can be deiodinated IEA Danio rerio 3041 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 3041 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 3041 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 3041 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 3041 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 3041 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 3041 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 3041 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 3041 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 3041 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 3041 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 3041 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 3041 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 3041 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 3041 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 3041 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 3041 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Danio rerio 3041 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 3041 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 3041 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 3041 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 3041 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 3041 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 3041 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 3041 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 3041 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 3041 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 3041 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 3041 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 3041 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 3041 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 3041 R-DRE-9915992 https://reactome.org/PathwayBrowser/#/R-DRE-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Danio rerio 3041 R-DRE-9915993 https://reactome.org/PathwayBrowser/#/R-DRE-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Danio rerio 3041 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 3041 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 3041 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 3041 R-GGA-194674 https://reactome.org/PathwayBrowser/#/R-GGA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Gallus gallus 3041 R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 3041 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 3041 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 3041 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 3041 R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 3041 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 3041 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 3041 R-GGA-209960 https://reactome.org/PathwayBrowser/#/R-GGA-209960 Diiodinated tyrosine can be deiodinated IEA Gallus gallus 3041 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 3041 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 3041 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 3041 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 3041 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 3041 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 3041 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 3041 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 3041 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 3041 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 3041 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 3041 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 3041 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 3041 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 3041 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 3041 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 3041 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 3041 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Gallus gallus 3041 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 3041 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 3041 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 3041 R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1 reduces O2 to H2O2 IEA Gallus gallus 3041 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 3041 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 3041 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 3041 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 3041 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 3041 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 3041 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 3041 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 3041 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 3041 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 3041 R-GGA-9915992 https://reactome.org/PathwayBrowser/#/R-GGA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Gallus gallus 3041 R-GGA-9915993 https://reactome.org/PathwayBrowser/#/R-GGA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Gallus gallus 3041 R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 3041 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 3041 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 3041 R-HSA-194674 https://reactome.org/PathwayBrowser/#/R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] TAS Homo sapiens 3041 R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 3041 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 3041 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 3041 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 3041 R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 3041 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 3041 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 3041 R-HSA-209960 https://reactome.org/PathwayBrowser/#/R-HSA-209960 Diiodinated tyrosine can be deiodinated TAS Homo sapiens 3041 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 3041 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 3041 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 3041 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 3041 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 3041 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 3041 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 3041 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 3041 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 3041 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 3041 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 3041 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 3041 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 3041 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 3041 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 3041 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 3041 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 3041 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 3041 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 3041 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 3041 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 3041 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 3041 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 3041 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) TAS Homo sapiens 3041 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 3041 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 3041 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 3041 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 3041 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 3041 R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 3041 R-HSA-5602242 https://reactome.org/PathwayBrowser/#/R-HSA-5602242 Defective CYP2U1 does not omega-hydroxylate ARA TAS Homo sapiens 3041 R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 3041 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 3041 R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1 reduces O2 to H2O2 TAS Homo sapiens 3041 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 3041 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 3041 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 3041 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 3041 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 3041 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 3041 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 3041 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 3041 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 3041 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 3041 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 3041 R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 3041 R-HSA-9915992 https://reactome.org/PathwayBrowser/#/R-HSA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) TAS Homo sapiens 3041 R-HSA-9915993 https://reactome.org/PathwayBrowser/#/R-HSA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) TAS Homo sapiens 3041 R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 3041 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 3041 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 3041 R-MMU-194674 https://reactome.org/PathwayBrowser/#/R-MMU-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Mus musculus 3041 R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 3041 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 3041 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 3041 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 3041 R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 3041 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 3041 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 3041 R-MMU-209960 https://reactome.org/PathwayBrowser/#/R-MMU-209960 Diiodinated tyrosine can be deiodinated IEA Mus musculus 3041 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 3041 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 3041 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 3041 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 3041 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 3041 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 3041 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 3041 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 3041 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 3041 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 3041 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 3041 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 3041 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 3041 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 3041 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 3041 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 3041 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 3041 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 3041 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 3041 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 3041 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 3041 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 3041 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 3041 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Mus musculus 3041 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 3041 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 3041 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 3041 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 3041 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 3041 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 3041 R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1 reduces O2 to H2O2 IEA Mus musculus 3041 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 3041 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 3041 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 3041 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 3041 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 3041 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 3041 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 3041 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 3041 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 3041 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 3041 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 3041 R-MMU-9915992 https://reactome.org/PathwayBrowser/#/R-MMU-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Mus musculus 3041 R-MMU-9915993 https://reactome.org/PathwayBrowser/#/R-MMU-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Mus musculus 3041 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 3041 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 3041 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 3041 R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 3041 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 3041 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 3041 R-RNO-194674 https://reactome.org/PathwayBrowser/#/R-RNO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Rattus norvegicus 3041 R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 3041 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 3041 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 3041 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 3041 R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 3041 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 3041 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 3041 R-RNO-209960 https://reactome.org/PathwayBrowser/#/R-RNO-209960 Diiodinated tyrosine can be deiodinated IEA Rattus norvegicus 3041 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 3041 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 3041 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 3041 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 3041 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 3041 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 3041 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 3041 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 3041 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 3041 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 3041 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 3041 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 3041 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 3041 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 3041 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 3041 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 3041 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 3041 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 3041 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 3041 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 3041 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 3041 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 3041 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 3041 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Rattus norvegicus 3041 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 3041 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 3041 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 3041 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 3041 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 3041 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 3041 R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1 reduces O2 to H2O2 IEA Rattus norvegicus 3041 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 3041 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 3041 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 3041 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 3041 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 3041 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 3041 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 3041 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 3041 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 3041 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 3041 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 3041 R-RNO-9915992 https://reactome.org/PathwayBrowser/#/R-RNO-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Rattus norvegicus 3041 R-RNO-9915993 https://reactome.org/PathwayBrowser/#/R-RNO-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Rattus norvegicus 3041 R-SCE-194674 https://reactome.org/PathwayBrowser/#/R-SCE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Saccharomyces cerevisiae 3041 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 3041 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 3041 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 3041 R-SPO-194674 https://reactome.org/PathwayBrowser/#/R-SPO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Schizosaccharomyces pombe 3041 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 3041 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 3041 R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa 3041 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 3041 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 3041 R-SSC-194674 https://reactome.org/PathwayBrowser/#/R-SSC-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Sus scrofa 3041 R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 3041 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 3041 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 3041 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 3041 R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 3041 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 3041 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 3041 R-SSC-209960 https://reactome.org/PathwayBrowser/#/R-SSC-209960 Diiodinated tyrosine can be deiodinated IEA Sus scrofa 3041 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 3041 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 3041 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 3041 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 3041 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 3041 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 3041 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 3041 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 3041 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 3041 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 3041 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 3041 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 3041 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 3041 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 3041 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 3041 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 3041 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 3041 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 3041 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 3041 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 3041 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 3041 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 3041 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 3041 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Sus scrofa 3041 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 3041 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 3041 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 3041 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 3041 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 3041 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 3041 R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1 reduces O2 to H2O2 IEA Sus scrofa 3041 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 3041 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 3041 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 3041 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 3041 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 3041 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 3041 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 3041 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 3041 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 3041 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 3041 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 3041 R-SSC-9915992 https://reactome.org/PathwayBrowser/#/R-SSC-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Sus scrofa 3041 R-SSC-9915993 https://reactome.org/PathwayBrowser/#/R-SSC-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Sus scrofa 3041 R-XTR-1236967 https://reactome.org/PathwayBrowser/#/R-XTR-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Xenopus tropicalis 3041 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 3041 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 3041 R-XTR-194674 https://reactome.org/PathwayBrowser/#/R-XTR-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Xenopus tropicalis 3041 R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 3041 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 3041 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 3041 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 3041 R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 3041 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 3041 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 3041 R-XTR-209960 https://reactome.org/PathwayBrowser/#/R-XTR-209960 Diiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 3041 R-XTR-209973 https://reactome.org/PathwayBrowser/#/R-XTR-209973 Tyrosine is diiodinated IEA Xenopus tropicalis 3041 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 3041 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 3041 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 3041 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 3041 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 3041 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 3041 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 3041 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 3041 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 3041 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 3041 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 3041 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 3041 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 3041 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 3041 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 3041 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 3041 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 3041 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 3041 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 3041 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 3041 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 3041 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 3041 R-XTR-350901 https://reactome.org/PathwayBrowser/#/R-XTR-350901 Iodide is organified IEA Xenopus tropicalis 3041 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 3041 R-XTR-5693681 https://reactome.org/PathwayBrowser/#/R-XTR-5693681 DUOX1 reduces O2 to H2O2 IEA Xenopus tropicalis 3041 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 3041 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 3041 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 3041 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 3041 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 3041 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 3041 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 3042 R-BTA-191352 https://reactome.org/PathwayBrowser/#/R-BTA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Bos taurus 3042 R-BTA-191380 https://reactome.org/PathwayBrowser/#/R-BTA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Bos taurus 3042 R-CEL-191352 https://reactome.org/PathwayBrowser/#/R-CEL-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Caenorhabditis elegans 3042 R-CEL-191380 https://reactome.org/PathwayBrowser/#/R-CEL-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Caenorhabditis elegans 3042 R-CFA-191352 https://reactome.org/PathwayBrowser/#/R-CFA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Canis familiaris 3042 R-CFA-191380 https://reactome.org/PathwayBrowser/#/R-CFA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Canis familiaris 3042 R-DDI-191352 https://reactome.org/PathwayBrowser/#/R-DDI-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Dictyostelium discoideum 3042 R-DDI-191380 https://reactome.org/PathwayBrowser/#/R-DDI-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Dictyostelium discoideum 3042 R-DME-191352 https://reactome.org/PathwayBrowser/#/R-DME-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Drosophila melanogaster 3042 R-DME-191380 https://reactome.org/PathwayBrowser/#/R-DME-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Drosophila melanogaster 3042 R-DRE-191352 https://reactome.org/PathwayBrowser/#/R-DRE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Danio rerio 3042 R-DRE-191380 https://reactome.org/PathwayBrowser/#/R-DRE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Danio rerio 3042 R-GGA-191352 https://reactome.org/PathwayBrowser/#/R-GGA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Gallus gallus 3042 R-GGA-191380 https://reactome.org/PathwayBrowser/#/R-GGA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Gallus gallus 3042 R-HSA-191352 https://reactome.org/PathwayBrowser/#/R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA TAS Homo sapiens 3042 R-HSA-191380 https://reactome.org/PathwayBrowser/#/R-HSA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate TAS Homo sapiens 3042 R-MMU-191352 https://reactome.org/PathwayBrowser/#/R-MMU-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Mus musculus 3042 R-MMU-191380 https://reactome.org/PathwayBrowser/#/R-MMU-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Mus musculus 3042 R-RNO-191352 https://reactome.org/PathwayBrowser/#/R-RNO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Rattus norvegicus 3042 R-RNO-191380 https://reactome.org/PathwayBrowser/#/R-RNO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Rattus norvegicus 3042 R-SCE-191352 https://reactome.org/PathwayBrowser/#/R-SCE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Saccharomyces cerevisiae 3042 R-SCE-191380 https://reactome.org/PathwayBrowser/#/R-SCE-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Saccharomyces cerevisiae 3042 R-SPO-191352 https://reactome.org/PathwayBrowser/#/R-SPO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Schizosaccharomyces pombe 3042 R-SPO-191380 https://reactome.org/PathwayBrowser/#/R-SPO-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Schizosaccharomyces pombe 3042 R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa 3042 R-SSC-191380 https://reactome.org/PathwayBrowser/#/R-SSC-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate IEA Sus scrofa 3042 R-XTR-191352 https://reactome.org/PathwayBrowser/#/R-XTR-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Xenopus tropicalis 3045 R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 3045 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 3045 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 3045 R-BTA-194674 https://reactome.org/PathwayBrowser/#/R-BTA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Bos taurus 3045 R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 3045 R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 3045 R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 3045 R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 3045 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 3045 R-BTA-209960 https://reactome.org/PathwayBrowser/#/R-BTA-209960 Diiodinated tyrosine can be deiodinated IEA Bos taurus 3045 R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 3045 R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 3045 R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 3045 R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 3045 R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 3045 R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 3045 R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 3045 R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 3045 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 3045 R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 3045 R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 3045 R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 3045 R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 3045 R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 3045 R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 3045 R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 3045 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 3045 R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 3045 R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 3045 R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 3045 R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 3045 R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 3045 R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Bos taurus 3045 R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 3045 R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 3045 R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 3045 R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 3045 R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 3045 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 3045 R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1 reduces O2 to H2O2 IEA Bos taurus 3045 R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 3045 R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 3045 R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 3045 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 3045 R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 3045 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 3045 R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 3045 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 3045 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 3045 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 3045 R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 3045 R-BTA-9915992 https://reactome.org/PathwayBrowser/#/R-BTA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Bos taurus 3045 R-BTA-9915993 https://reactome.org/PathwayBrowser/#/R-BTA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Bos taurus 3045 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 3045 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 3045 R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 3045 R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 3045 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 3045 R-CEL-209960 https://reactome.org/PathwayBrowser/#/R-CEL-209960 Diiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 3045 R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 3045 R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 3045 R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 3045 R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 3045 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 3045 R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 3045 R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 3045 R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 3045 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 3045 R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 3045 R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 3045 R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 3045 R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 3045 R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 3045 R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 3045 R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 3045 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 3045 R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1 reduces O2 to H2O2 IEA Caenorhabditis elegans 3045 R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 3045 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 3045 R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 3045 R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 3045 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 3045 R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 3045 R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 3045 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 3045 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 3045 R-CFA-194674 https://reactome.org/PathwayBrowser/#/R-CFA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Canis familiaris 3045 R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 3045 R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 3045 R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 3045 R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 3045 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 3045 R-CFA-209960 https://reactome.org/PathwayBrowser/#/R-CFA-209960 Diiodinated tyrosine can be deiodinated IEA Canis familiaris 3045 R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 3045 R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 3045 R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 3045 R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 3045 R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 3045 R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 3045 R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 3045 R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 3045 R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 3045 R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 3045 R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 3045 R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 3045 R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 3045 R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 3045 R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 3045 R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 3045 R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 3045 R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 3045 R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Canis familiaris 3045 R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 3045 R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 3045 R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 3045 R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 3045 R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 3045 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 3045 R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1 reduces O2 to H2O2 IEA Canis familiaris 3045 R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 3045 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 3045 R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 3045 R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 3045 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 3045 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 3045 R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 3045 R-CFA-9915992 https://reactome.org/PathwayBrowser/#/R-CFA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Canis familiaris 3045 R-CFA-9915993 https://reactome.org/PathwayBrowser/#/R-CFA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Canis familiaris 3045 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 3045 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 3045 R-DDI-194674 https://reactome.org/PathwayBrowser/#/R-DDI-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Dictyostelium discoideum 3045 R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 3045 R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 3045 R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 3045 R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 3045 R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 3045 R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 3045 R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 3045 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 3045 R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 3045 R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 3045 R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 3045 R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 3045 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 3045 R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 3045 R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 3045 R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 3045 R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 3045 R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 3045 R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 3045 R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 3045 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 3045 R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 3045 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 3045 R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 3045 R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 3045 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 3045 R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 3045 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 3045 R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 3045 R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 3045 R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 3045 R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 3045 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 3045 R-DME-209960 https://reactome.org/PathwayBrowser/#/R-DME-209960 Diiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 3045 R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 3045 R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 3045 R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 3045 R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 3045 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 3045 R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 3045 R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 3045 R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 3045 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 3045 R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 3045 R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 3045 R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 3045 R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 3045 R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 3045 R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1 reduces O2 to H2O2 IEA Drosophila melanogaster 3045 R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 3045 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 3045 R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 3045 R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 3045 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 3045 R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 3045 R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 3045 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 3045 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 3045 R-DRE-194674 https://reactome.org/PathwayBrowser/#/R-DRE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Danio rerio 3045 R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 3045 R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 3045 R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 3045 R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 3045 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 3045 R-DRE-209960 https://reactome.org/PathwayBrowser/#/R-DRE-209960 Diiodinated tyrosine can be deiodinated IEA Danio rerio 3045 R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 3045 R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 3045 R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 3045 R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 3045 R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 3045 R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 3045 R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 3045 R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 3045 R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 3045 R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 3045 R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 3045 R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 3045 R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 3045 R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 3045 R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 3045 R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 3045 R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Danio rerio 3045 R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 3045 R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 3045 R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 3045 R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 3045 R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 3045 R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 3045 R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 3045 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 3045 R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 3045 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 3045 R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 3045 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 3045 R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 3045 R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 3045 R-DRE-9915992 https://reactome.org/PathwayBrowser/#/R-DRE-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Danio rerio 3045 R-DRE-9915993 https://reactome.org/PathwayBrowser/#/R-DRE-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Danio rerio 3045 R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 3045 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 3045 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 3045 R-GGA-194674 https://reactome.org/PathwayBrowser/#/R-GGA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Gallus gallus 3045 R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 3045 R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 3045 R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 3045 R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 3045 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 3045 R-GGA-209960 https://reactome.org/PathwayBrowser/#/R-GGA-209960 Diiodinated tyrosine can be deiodinated IEA Gallus gallus 3045 R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 3045 R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 3045 R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 3045 R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 3045 R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 3045 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 3045 R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 3045 R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 3045 R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 3045 R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 3045 R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 3045 R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 3045 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 3045 R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 3045 R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 3045 R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 3045 R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 3045 R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Gallus gallus 3045 R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 3045 R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 3045 R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 3045 R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1 reduces O2 to H2O2 IEA Gallus gallus 3045 R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 3045 R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 3045 R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 3045 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 3045 R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 3045 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 3045 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 3045 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 3045 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 3045 R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 3045 R-GGA-9915992 https://reactome.org/PathwayBrowser/#/R-GGA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Gallus gallus 3045 R-GGA-9915993 https://reactome.org/PathwayBrowser/#/R-GGA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Gallus gallus 3045 R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 3045 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 3045 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 3045 R-HSA-194674 https://reactome.org/PathwayBrowser/#/R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] TAS Homo sapiens 3045 R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 3045 R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 3045 R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 3045 R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 3045 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 3045 R-HSA-209960 https://reactome.org/PathwayBrowser/#/R-HSA-209960 Diiodinated tyrosine can be deiodinated TAS Homo sapiens 3045 R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 3045 R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 3045 R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 3045 R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 3045 R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 3045 R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 3045 R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 3045 R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 3045 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 3045 R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 3045 R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 3045 R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 3045 R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 3045 R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 3045 R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 3045 R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 3045 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 3045 R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 3045 R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 3045 R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 3045 R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 3045 R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 3045 R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 3045 R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) TAS Homo sapiens 3045 R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 3045 R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 3045 R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 3045 R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 3045 R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 3045 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 3045 R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1 reduces O2 to H2O2 TAS Homo sapiens 3045 R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 3045 R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 3045 R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 3045 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 3045 R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 3045 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 3045 R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 3045 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 3045 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 3045 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 3045 R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 3045 R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 3045 R-HSA-9915992 https://reactome.org/PathwayBrowser/#/R-HSA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) TAS Homo sapiens 3045 R-HSA-9915993 https://reactome.org/PathwayBrowser/#/R-HSA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) TAS Homo sapiens 3045 R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 3045 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 3045 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 3045 R-MMU-194674 https://reactome.org/PathwayBrowser/#/R-MMU-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Mus musculus 3045 R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 3045 R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 3045 R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 3045 R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 3045 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 3045 R-MMU-209960 https://reactome.org/PathwayBrowser/#/R-MMU-209960 Diiodinated tyrosine can be deiodinated IEA Mus musculus 3045 R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 3045 R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 3045 R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 3045 R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 3045 R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 3045 R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 3045 R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 3045 R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 3045 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 3045 R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 3045 R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 3045 R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 3045 R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 3045 R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 3045 R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 3045 R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 3045 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 3045 R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 3045 R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 3045 R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 3045 R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 3045 R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 3045 R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 3045 R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Mus musculus 3045 R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 3045 R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 3045 R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 3045 R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 3045 R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 3045 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 3045 R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1 reduces O2 to H2O2 IEA Mus musculus 3045 R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 3045 R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 3045 R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 3045 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 3045 R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 3045 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 3045 R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 3045 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 3045 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 3045 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 3045 R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 3045 R-MMU-9915992 https://reactome.org/PathwayBrowser/#/R-MMU-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Mus musculus 3045 R-MMU-9915993 https://reactome.org/PathwayBrowser/#/R-MMU-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Mus musculus 3045 R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 3045 R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 3045 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 3045 R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 3045 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 3045 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 3045 R-RNO-194674 https://reactome.org/PathwayBrowser/#/R-RNO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Rattus norvegicus 3045 R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 3045 R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 3045 R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 3045 R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 3045 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 3045 R-RNO-209960 https://reactome.org/PathwayBrowser/#/R-RNO-209960 Diiodinated tyrosine can be deiodinated IEA Rattus norvegicus 3045 R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 3045 R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 3045 R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 3045 R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 3045 R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 3045 R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 3045 R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 3045 R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 3045 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 3045 R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 3045 R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 3045 R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 3045 R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 3045 R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 3045 R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 3045 R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 3045 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 3045 R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 3045 R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 3045 R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 3045 R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 3045 R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 3045 R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 3045 R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Rattus norvegicus 3045 R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 3045 R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 3045 R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 3045 R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 3045 R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 3045 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 3045 R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1 reduces O2 to H2O2 IEA Rattus norvegicus 3045 R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 3045 R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 3045 R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 3045 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 3045 R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 3045 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 3045 R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 3045 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 3045 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 3045 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 3045 R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 3045 R-RNO-9915992 https://reactome.org/PathwayBrowser/#/R-RNO-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Rattus norvegicus 3045 R-RNO-9915993 https://reactome.org/PathwayBrowser/#/R-RNO-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Rattus norvegicus 3045 R-SCE-194674 https://reactome.org/PathwayBrowser/#/R-SCE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Saccharomyces cerevisiae 3045 R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 3045 R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 3045 R-SCE-6790127 https://reactome.org/PathwayBrowser/#/R-SCE-6790127 SMM1 (DUS2) reduces uridine-20 to dihydrouridine in tRNA(Leu) TAS Saccharomyces cerevisiae 3045 R-SPO-194674 https://reactome.org/PathwayBrowser/#/R-SPO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Schizosaccharomyces pombe 3045 R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 3045 R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 3045 R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa 3045 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 3045 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 3045 R-SSC-194674 https://reactome.org/PathwayBrowser/#/R-SSC-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Sus scrofa 3045 R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 3045 R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 3045 R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 3045 R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 3045 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 3045 R-SSC-209960 https://reactome.org/PathwayBrowser/#/R-SSC-209960 Diiodinated tyrosine can be deiodinated IEA Sus scrofa 3045 R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 3045 R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 3045 R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 3045 R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 3045 R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 3045 R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 3045 R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 3045 R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 3045 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 3045 R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 3045 R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 3045 R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 3045 R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 3045 R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 3045 R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 3045 R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 3045 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 3045 R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 3045 R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 3045 R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 3045 R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 3045 R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 3045 R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 3045 R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Sus scrofa 3045 R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 3045 R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 3045 R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 3045 R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 3045 R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 3045 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 3045 R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1 reduces O2 to H2O2 IEA Sus scrofa 3045 R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 3045 R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 3045 R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 3045 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 3045 R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 3045 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 3045 R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 3045 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 3045 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 3045 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 3045 R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 3045 R-SSC-9915992 https://reactome.org/PathwayBrowser/#/R-SSC-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Sus scrofa 3045 R-SSC-9915993 https://reactome.org/PathwayBrowser/#/R-SSC-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Sus scrofa 3045 R-XTR-1236967 https://reactome.org/PathwayBrowser/#/R-XTR-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Xenopus tropicalis 3045 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 3045 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 3045 R-XTR-194674 https://reactome.org/PathwayBrowser/#/R-XTR-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Xenopus tropicalis 3045 R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 3045 R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 3045 R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 3045 R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 3045 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 3045 R-XTR-209960 https://reactome.org/PathwayBrowser/#/R-XTR-209960 Diiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 3045 R-XTR-209973 https://reactome.org/PathwayBrowser/#/R-XTR-209973 Tyrosine is diiodinated IEA Xenopus tropicalis 3045 R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 3045 R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 3045 R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 3045 R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 3045 R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 3045 R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 3045 R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 3045 R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 3045 R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 3045 R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 3045 R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 3045 R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 3045 R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 3045 R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 3045 R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 3045 R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 3045 R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 3045 R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 3045 R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 3045 R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 3045 R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 3045 R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 3045 R-XTR-350901 https://reactome.org/PathwayBrowser/#/R-XTR-350901 Iodide is organified IEA Xenopus tropicalis 3045 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 3045 R-XTR-5693681 https://reactome.org/PathwayBrowser/#/R-XTR-5693681 DUOX1 reduces O2 to H2O2 IEA Xenopus tropicalis 3045 R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 3045 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 3045 R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 3045 R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 3045 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 3045 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 3045 R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 3052 R-BTA-8870465 https://reactome.org/PathwayBrowser/#/R-BTA-8870465 RGGT binds the RAB-binding subunit IEA Bos taurus 3052 R-BTA-8870466 https://reactome.org/PathwayBrowser/#/R-BTA-8870466 RGGT:CHM binds RABs IEA Bos taurus 3052 R-BTA-8870469 https://reactome.org/PathwayBrowser/#/R-BTA-8870469 RGGT geranylgeranylates RAB proteins IEA Bos taurus 3052 R-CEL-8870465 https://reactome.org/PathwayBrowser/#/R-CEL-8870465 RGGT binds the RAB-binding subunit IEA Caenorhabditis elegans 3052 R-CEL-8870466 https://reactome.org/PathwayBrowser/#/R-CEL-8870466 RGGT:CHM binds RABs IEA Caenorhabditis elegans 3052 R-CEL-8870469 https://reactome.org/PathwayBrowser/#/R-CEL-8870469 RGGT geranylgeranylates RAB proteins IEA Caenorhabditis elegans 3052 R-CFA-8870465 https://reactome.org/PathwayBrowser/#/R-CFA-8870465 RGGT binds the RAB-binding subunit IEA Canis familiaris 3052 R-CFA-8870466 https://reactome.org/PathwayBrowser/#/R-CFA-8870466 RGGT:CHM binds RABs IEA Canis familiaris 3052 R-CFA-8870469 https://reactome.org/PathwayBrowser/#/R-CFA-8870469 RGGT geranylgeranylates RAB proteins IEA Canis familiaris 3052 R-DDI-8870465 https://reactome.org/PathwayBrowser/#/R-DDI-8870465 RGGT binds the RAB-binding subunit IEA Dictyostelium discoideum 3052 R-DDI-8870466 https://reactome.org/PathwayBrowser/#/R-DDI-8870466 RGGT:CHM binds RABs IEA Dictyostelium discoideum 3052 R-DDI-8870469 https://reactome.org/PathwayBrowser/#/R-DDI-8870469 RGGT geranylgeranylates RAB proteins IEA Dictyostelium discoideum 3052 R-DME-8870465 https://reactome.org/PathwayBrowser/#/R-DME-8870465 RGGT binds the RAB-binding subunit IEA Drosophila melanogaster 3052 R-DME-8870466 https://reactome.org/PathwayBrowser/#/R-DME-8870466 RGGT:CHM binds RABs IEA Drosophila melanogaster 3052 R-DME-8870469 https://reactome.org/PathwayBrowser/#/R-DME-8870469 RGGT geranylgeranylates RAB proteins IEA Drosophila melanogaster 3052 R-DRE-8870465 https://reactome.org/PathwayBrowser/#/R-DRE-8870465 RGGT binds the RAB-binding subunit IEA Danio rerio 3052 R-DRE-8870466 https://reactome.org/PathwayBrowser/#/R-DRE-8870466 RGGT:CHM binds RABs IEA Danio rerio 3052 R-DRE-8870469 https://reactome.org/PathwayBrowser/#/R-DRE-8870469 RGGT geranylgeranylates RAB proteins IEA Danio rerio 3052 R-HSA-8870465 https://reactome.org/PathwayBrowser/#/R-HSA-8870465 RGGT binds the RAB-binding subunit TAS Homo sapiens 3052 R-HSA-8870466 https://reactome.org/PathwayBrowser/#/R-HSA-8870466 RGGT:CHM binds RABs TAS Homo sapiens 3052 R-HSA-8870469 https://reactome.org/PathwayBrowser/#/R-HSA-8870469 RGGT geranylgeranylates RAB proteins TAS Homo sapiens 3052 R-MMU-8870465 https://reactome.org/PathwayBrowser/#/R-MMU-8870465 RGGT binds the RAB-binding subunit IEA Mus musculus 3052 R-MMU-8870466 https://reactome.org/PathwayBrowser/#/R-MMU-8870466 RGGT:CHM binds RABs IEA Mus musculus 3052 R-MMU-8870469 https://reactome.org/PathwayBrowser/#/R-MMU-8870469 RGGT geranylgeranylates RAB proteins IEA Mus musculus 3052 R-PFA-8870465 https://reactome.org/PathwayBrowser/#/R-PFA-8870465 RGGT binds the RAB-binding subunit IEA Plasmodium falciparum 3052 R-PFA-8870466 https://reactome.org/PathwayBrowser/#/R-PFA-8870466 RGGT:CHM binds RABs IEA Plasmodium falciparum 3052 R-PFA-8870469 https://reactome.org/PathwayBrowser/#/R-PFA-8870469 RGGT geranylgeranylates RAB proteins IEA Plasmodium falciparum 3052 R-RNO-8870465 https://reactome.org/PathwayBrowser/#/R-RNO-8870465 RGGT binds the RAB-binding subunit IEA Rattus norvegicus 3052 R-RNO-8870466 https://reactome.org/PathwayBrowser/#/R-RNO-8870466 RGGT:CHM binds RABs IEA Rattus norvegicus 3052 R-RNO-8870469 https://reactome.org/PathwayBrowser/#/R-RNO-8870469 RGGT geranylgeranylates RAB proteins IEA Rattus norvegicus 3052 R-SCE-8870465 https://reactome.org/PathwayBrowser/#/R-SCE-8870465 RGGT binds the RAB-binding subunit IEA Saccharomyces cerevisiae 3052 R-SCE-8870466 https://reactome.org/PathwayBrowser/#/R-SCE-8870466 RGGT:CHM binds RABs IEA Saccharomyces cerevisiae 3052 R-SCE-8870469 https://reactome.org/PathwayBrowser/#/R-SCE-8870469 RGGT geranylgeranylates RAB proteins IEA Saccharomyces cerevisiae 3052 R-SPO-8870465 https://reactome.org/PathwayBrowser/#/R-SPO-8870465 RGGT binds the RAB-binding subunit IEA Schizosaccharomyces pombe 3052 R-SPO-8870466 https://reactome.org/PathwayBrowser/#/R-SPO-8870466 RGGT:CHM binds RABs IEA Schizosaccharomyces pombe 3052 R-SPO-8870469 https://reactome.org/PathwayBrowser/#/R-SPO-8870469 RGGT geranylgeranylates RAB proteins IEA Schizosaccharomyces pombe 3054 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 3054 R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 3054 R-BTA-8850326 https://reactome.org/PathwayBrowser/#/R-BTA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Bos taurus 3054 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 3054 R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 3054 R-CFA-8850326 https://reactome.org/PathwayBrowser/#/R-CFA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Canis familiaris 3054 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 3054 R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 3054 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 3054 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 3054 R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 3054 R-GGA-8850326 https://reactome.org/PathwayBrowser/#/R-GGA-8850326 TCR binds self-lipid-based antigen via CD1 IEA Gallus gallus 3054 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 3054 R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 3054 R-HSA-8850326 https://reactome.org/PathwayBrowser/#/R-HSA-8850326 TCR binds self-lipid-based antigen via CD1 TAS Homo sapiens 3054 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 3054 R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 3054 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 3054 R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 3054 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 3054 R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 3054 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 3054 R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 3054 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 3054 R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 3054 R-SSC-8850326 https://reactome.org/PathwayBrowser/#/R-SSC-8850326 TCR binds self-lipid-based antigen via CD1 IEA Sus scrofa 3054 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 3054 R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 3059 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 3059 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 3059 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 3059 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 3059 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 3059 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 3059 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 3059 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 3059 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 3059 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 3059 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 3059 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 3059 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 3141 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 3141 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 3141 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 3141 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 3141 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 3141 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 3141 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 3141 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 3141 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 3141 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 3141 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 3141 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 3141 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 316 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 316 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 316 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 316 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 316 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 316 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 316 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 316 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 316 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 316 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 316 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 3164 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 3164 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 3164 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 3164 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 3164 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 3164 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 3164 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 3164 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 3164 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 3164 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 3164 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 3164 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 3164 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 3176 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 3176 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 3176 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 3176 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 3176 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 3176 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 3176 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 3176 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 3176 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 3176 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 3176 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 3176 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 3176 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 3177 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 3177 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 3177 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 3177 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 3177 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 3177 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 3177 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 3177 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 3177 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 3177 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 3177 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 3177 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 3177 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 320 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 320 R-BTA-9704297 https://reactome.org/PathwayBrowser/#/R-BTA-9704297 CHRM2 binds CHRM2 antagonists IEA Bos taurus 320 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 320 R-CEL-9704297 https://reactome.org/PathwayBrowser/#/R-CEL-9704297 CHRM2 binds CHRM2 antagonists IEA Caenorhabditis elegans 320 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 320 R-CFA-9704297 https://reactome.org/PathwayBrowser/#/R-CFA-9704297 CHRM2 binds CHRM2 antagonists IEA Canis familiaris 320 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 320 R-DME-9704297 https://reactome.org/PathwayBrowser/#/R-DME-9704297 CHRM2 binds CHRM2 antagonists IEA Drosophila melanogaster 320 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 320 R-DRE-9704297 https://reactome.org/PathwayBrowser/#/R-DRE-9704297 CHRM2 binds CHRM2 antagonists IEA Danio rerio 320 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 320 R-GGA-9704297 https://reactome.org/PathwayBrowser/#/R-GGA-9704297 CHRM2 binds CHRM2 antagonists IEA Gallus gallus 320 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 320 R-HSA-9704297 https://reactome.org/PathwayBrowser/#/R-HSA-9704297 CHRM2 binds CHRM2 antagonists TAS Homo sapiens 320 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 320 R-MMU-9704297 https://reactome.org/PathwayBrowser/#/R-MMU-9704297 CHRM2 binds CHRM2 antagonists IEA Mus musculus 320 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 320 R-RNO-9704297 https://reactome.org/PathwayBrowser/#/R-RNO-9704297 CHRM2 binds CHRM2 antagonists IEA Rattus norvegicus 320 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 320 R-SSC-9704297 https://reactome.org/PathwayBrowser/#/R-SSC-9704297 CHRM2 binds CHRM2 antagonists IEA Sus scrofa 320 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 320 R-XTR-9704297 https://reactome.org/PathwayBrowser/#/R-XTR-9704297 CHRM2 binds CHRM2 antagonists IEA Xenopus tropicalis 321 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 321 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 321 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 321 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 321 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 321 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 321 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 321 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 321 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 321 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 321 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 3215 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 3215 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 3215 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 3215 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 3215 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 3215 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 3215 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 3215 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 3215 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 325 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 325 R-BTA-9704297 https://reactome.org/PathwayBrowser/#/R-BTA-9704297 CHRM2 binds CHRM2 antagonists IEA Bos taurus 325 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 325 R-CEL-9704297 https://reactome.org/PathwayBrowser/#/R-CEL-9704297 CHRM2 binds CHRM2 antagonists IEA Caenorhabditis elegans 325 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 325 R-CFA-9704297 https://reactome.org/PathwayBrowser/#/R-CFA-9704297 CHRM2 binds CHRM2 antagonists IEA Canis familiaris 325 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 325 R-DME-9704297 https://reactome.org/PathwayBrowser/#/R-DME-9704297 CHRM2 binds CHRM2 antagonists IEA Drosophila melanogaster 325 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 325 R-DRE-9704297 https://reactome.org/PathwayBrowser/#/R-DRE-9704297 CHRM2 binds CHRM2 antagonists IEA Danio rerio 325 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 325 R-GGA-9704297 https://reactome.org/PathwayBrowser/#/R-GGA-9704297 CHRM2 binds CHRM2 antagonists IEA Gallus gallus 325 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 325 R-HSA-9704297 https://reactome.org/PathwayBrowser/#/R-HSA-9704297 CHRM2 binds CHRM2 antagonists TAS Homo sapiens 325 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 325 R-MMU-9704297 https://reactome.org/PathwayBrowser/#/R-MMU-9704297 CHRM2 binds CHRM2 antagonists IEA Mus musculus 325 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 325 R-RNO-9704297 https://reactome.org/PathwayBrowser/#/R-RNO-9704297 CHRM2 binds CHRM2 antagonists IEA Rattus norvegicus 325 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 325 R-SSC-9704297 https://reactome.org/PathwayBrowser/#/R-SSC-9704297 CHRM2 binds CHRM2 antagonists IEA Sus scrofa 325 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 325 R-XTR-9704297 https://reactome.org/PathwayBrowser/#/R-XTR-9704297 CHRM2 binds CHRM2 antagonists IEA Xenopus tropicalis 328 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 328 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 328 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 328 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 328 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 328 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 328 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 328 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 328 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 328 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 328 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 329 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 329 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 329 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 329 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 329 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 329 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 329 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 329 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 329 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 329 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 329 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 33 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 33 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 33 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 33 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 33 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 33 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 33 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 33 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 33 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 33 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 330 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 330 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 330 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 330 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 330 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 330 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 330 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 330 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 330 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 330 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 330 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 3308 R-BTA-9703895 https://reactome.org/PathwayBrowser/#/R-BTA-9703895 CASR binds CASR agonists IEA Bos taurus 3308 R-CFA-9703895 https://reactome.org/PathwayBrowser/#/R-CFA-9703895 CASR binds CASR agonists IEA Canis familiaris 3308 R-GGA-9703895 https://reactome.org/PathwayBrowser/#/R-GGA-9703895 CASR binds CASR agonists IEA Gallus gallus 3308 R-HSA-9703895 https://reactome.org/PathwayBrowser/#/R-HSA-9703895 CASR binds CASR agonists TAS Homo sapiens 3308 R-MMU-9703895 https://reactome.org/PathwayBrowser/#/R-MMU-9703895 CASR binds CASR agonists IEA Mus musculus 3308 R-RNO-9703895 https://reactome.org/PathwayBrowser/#/R-RNO-9703895 CASR binds CASR agonists IEA Rattus norvegicus 3308 R-SSC-9703895 https://reactome.org/PathwayBrowser/#/R-SSC-9703895 CASR binds CASR agonists IEA Sus scrofa 3308 R-XTR-9703895 https://reactome.org/PathwayBrowser/#/R-XTR-9703895 CASR binds CASR agonists IEA Xenopus tropicalis 3322 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 3322 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 3322 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 3322 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 3322 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 3322 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 3322 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 3322 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 3322 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 3322 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 3322 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 3322 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 3322 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 3322 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 3322 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 3322 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 3322 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 3322 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 3322 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 3322 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 3327 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 3327 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 3327 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 3327 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 3327 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 3327 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 3327 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 3327 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 3327 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 3327 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 3327 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 3327 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 3327 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 3327 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 3327 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 3327 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 3327 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 3327 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 3327 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 3327 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 3329 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 3329 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 3329 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 3329 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 3329 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 3329 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 3329 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 3329 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 3329 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 3329 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 3329 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 3329 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 3329 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 3329 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 3329 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 3329 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 3329 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 3329 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 3329 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 3329 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 3334 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 3334 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 3334 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 3334 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 3334 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 3334 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 3334 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 3334 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 3334 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 3334 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 3334 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 3334 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 3334 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 3334 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 3334 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 3334 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 3334 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 3334 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 3334 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 3334 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 3340 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 3340 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 3340 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 3340 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 3340 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 3340 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 3340 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 3340 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 3340 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 3340 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 3340 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 3340 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 3340 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 3340 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 3340 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 3340 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 3340 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 3340 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 3340 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 3340 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 3381 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 3381 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 3381 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 3381 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 3381 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 3381 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 3381 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 3381 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 3381 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 3381 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 3381 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 3381 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 3381 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 3381 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 3381 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 3381 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 3381 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 3381 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 3381 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 3381 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 34 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 34 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 34 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 34 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 34 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 34 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 34 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 34 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 34 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 34 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 34 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 34 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 34 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 34 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 34 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 34 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 34 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 34 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 34 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 34 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 34 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 34 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 34 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 34 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 34 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 34 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 34 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 34 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 342 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 342 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 342 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 342 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 342 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 342 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 342 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 342 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 342 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 342 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 342 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 342 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 342 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 342 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 342 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 342 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 342 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 342 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 342 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 342 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 342 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 342 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 342 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 342 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 342 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 342 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 342 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 342 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 342 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 342 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 342 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 342 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 342 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 342 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 342 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 342 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 342 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 342 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 342 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 342 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 342 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 342 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 3438 R-BTA-9734475 https://reactome.org/PathwayBrowser/#/R-BTA-9734475 PPARA binds fibrates IEA Bos taurus 3438 R-CFA-9734475 https://reactome.org/PathwayBrowser/#/R-CFA-9734475 PPARA binds fibrates IEA Canis familiaris 3438 R-DME-9734475 https://reactome.org/PathwayBrowser/#/R-DME-9734475 PPARA binds fibrates IEA Drosophila melanogaster 3438 R-DRE-9734475 https://reactome.org/PathwayBrowser/#/R-DRE-9734475 PPARA binds fibrates IEA Danio rerio 3438 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus 3438 R-HSA-9734475 https://reactome.org/PathwayBrowser/#/R-HSA-9734475 PPARA binds fibrates TAS Homo sapiens 3438 R-MMU-9734475 https://reactome.org/PathwayBrowser/#/R-MMU-9734475 PPARA binds fibrates IEA Mus musculus 3438 R-RNO-9734475 https://reactome.org/PathwayBrowser/#/R-RNO-9734475 PPARA binds fibrates IEA Rattus norvegicus 3438 R-SSC-9734475 https://reactome.org/PathwayBrowser/#/R-SSC-9734475 PPARA binds fibrates IEA Sus scrofa 3438 R-XTR-9734475 https://reactome.org/PathwayBrowser/#/R-XTR-9734475 PPARA binds fibrates IEA Xenopus tropicalis 3439 R-BTA-9734475 https://reactome.org/PathwayBrowser/#/R-BTA-9734475 PPARA binds fibrates IEA Bos taurus 3439 R-CFA-9734475 https://reactome.org/PathwayBrowser/#/R-CFA-9734475 PPARA binds fibrates IEA Canis familiaris 3439 R-DME-9734475 https://reactome.org/PathwayBrowser/#/R-DME-9734475 PPARA binds fibrates IEA Drosophila melanogaster 3439 R-DRE-9734475 https://reactome.org/PathwayBrowser/#/R-DRE-9734475 PPARA binds fibrates IEA Danio rerio 3439 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus 3439 R-HSA-9734475 https://reactome.org/PathwayBrowser/#/R-HSA-9734475 PPARA binds fibrates TAS Homo sapiens 3439 R-MMU-9734475 https://reactome.org/PathwayBrowser/#/R-MMU-9734475 PPARA binds fibrates IEA Mus musculus 3439 R-RNO-9734475 https://reactome.org/PathwayBrowser/#/R-RNO-9734475 PPARA binds fibrates IEA Rattus norvegicus 3439 R-SSC-9734475 https://reactome.org/PathwayBrowser/#/R-SSC-9734475 PPARA binds fibrates IEA Sus scrofa 3439 R-XTR-9734475 https://reactome.org/PathwayBrowser/#/R-XTR-9734475 PPARA binds fibrates IEA Xenopus tropicalis 3469 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 3469 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 3469 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 3469 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 3469 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 3469 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 3469 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 3469 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 3469 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 3469 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 3469 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 3469 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 3469 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 3469 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 3469 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 3469 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 3469 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 3469 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 3469 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 3469 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 3469 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 3469 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 347 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 347 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 347 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 347 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 347 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 347 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 347 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 347 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 347 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 347 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 347 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 347 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 347 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 347 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 347 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 347 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 347 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 347 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 347 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 347 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 347 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 347 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 347 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 347 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 347 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 347 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 347 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 347 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 347 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 347 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 347 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 347 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 347 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 347 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 347 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 347 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 347 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 347 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 347 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 347 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 347 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 347 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 3494 R-BTA-9731393 https://reactome.org/PathwayBrowser/#/R-BTA-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Bos taurus 3494 R-CFA-9731393 https://reactome.org/PathwayBrowser/#/R-CFA-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Canis familiaris 3494 R-DRE-9731393 https://reactome.org/PathwayBrowser/#/R-DRE-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Danio rerio 3494 R-GGA-9731393 https://reactome.org/PathwayBrowser/#/R-GGA-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Gallus gallus 3494 R-HSA-9731393 https://reactome.org/PathwayBrowser/#/R-HSA-9731393 EDNRA, EDNRB bind non-selective ERAs TAS Homo sapiens 3494 R-MMU-9731393 https://reactome.org/PathwayBrowser/#/R-MMU-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Mus musculus 3494 R-RNO-9731393 https://reactome.org/PathwayBrowser/#/R-RNO-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Rattus norvegicus 3494 R-SSC-9731393 https://reactome.org/PathwayBrowser/#/R-SSC-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Sus scrofa 3494 R-XTR-9731393 https://reactome.org/PathwayBrowser/#/R-XTR-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Xenopus tropicalis 35 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 35 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 35 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 35 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 35 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 35 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 35 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 35 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 35 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 35 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 355 R-BTA-9704297 https://reactome.org/PathwayBrowser/#/R-BTA-9704297 CHRM2 binds CHRM2 antagonists IEA Bos taurus 355 R-CEL-9704248 https://reactome.org/PathwayBrowser/#/R-CEL-9704248 CHRM4 binds CHRM4 antagonists IEA Caenorhabditis elegans 355 R-CEL-9704297 https://reactome.org/PathwayBrowser/#/R-CEL-9704297 CHRM2 binds CHRM2 antagonists IEA Caenorhabditis elegans 355 R-CFA-9704248 https://reactome.org/PathwayBrowser/#/R-CFA-9704248 CHRM4 binds CHRM4 antagonists IEA Canis familiaris 355 R-CFA-9704297 https://reactome.org/PathwayBrowser/#/R-CFA-9704297 CHRM2 binds CHRM2 antagonists IEA Canis familiaris 355 R-DME-9704248 https://reactome.org/PathwayBrowser/#/R-DME-9704248 CHRM4 binds CHRM4 antagonists IEA Drosophila melanogaster 355 R-DME-9704297 https://reactome.org/PathwayBrowser/#/R-DME-9704297 CHRM2 binds CHRM2 antagonists IEA Drosophila melanogaster 355 R-DRE-9704297 https://reactome.org/PathwayBrowser/#/R-DRE-9704297 CHRM2 binds CHRM2 antagonists IEA Danio rerio 355 R-GGA-9704248 https://reactome.org/PathwayBrowser/#/R-GGA-9704248 CHRM4 binds CHRM4 antagonists IEA Gallus gallus 355 R-GGA-9704297 https://reactome.org/PathwayBrowser/#/R-GGA-9704297 CHRM2 binds CHRM2 antagonists IEA Gallus gallus 355 R-HSA-9704248 https://reactome.org/PathwayBrowser/#/R-HSA-9704248 CHRM4 binds CHRM4 antagonists TAS Homo sapiens 355 R-HSA-9704297 https://reactome.org/PathwayBrowser/#/R-HSA-9704297 CHRM2 binds CHRM2 antagonists TAS Homo sapiens 355 R-MMU-9704248 https://reactome.org/PathwayBrowser/#/R-MMU-9704248 CHRM4 binds CHRM4 antagonists IEA Mus musculus 355 R-MMU-9704297 https://reactome.org/PathwayBrowser/#/R-MMU-9704297 CHRM2 binds CHRM2 antagonists IEA Mus musculus 355 R-RNO-9704248 https://reactome.org/PathwayBrowser/#/R-RNO-9704248 CHRM4 binds CHRM4 antagonists IEA Rattus norvegicus 355 R-RNO-9704297 https://reactome.org/PathwayBrowser/#/R-RNO-9704297 CHRM2 binds CHRM2 antagonists IEA Rattus norvegicus 355 R-SSC-9704248 https://reactome.org/PathwayBrowser/#/R-SSC-9704248 CHRM4 binds CHRM4 antagonists IEA Sus scrofa 355 R-SSC-9704297 https://reactome.org/PathwayBrowser/#/R-SSC-9704297 CHRM2 binds CHRM2 antagonists IEA Sus scrofa 355 R-XTR-9704248 https://reactome.org/PathwayBrowser/#/R-XTR-9704248 CHRM4 binds CHRM4 antagonists IEA Xenopus tropicalis 355 R-XTR-9704297 https://reactome.org/PathwayBrowser/#/R-XTR-9704297 CHRM2 binds CHRM2 antagonists IEA Xenopus tropicalis 357 R-BTA-549304 https://reactome.org/PathwayBrowser/#/R-BTA-549304 OCT3 mediates renal clearance of organic cations IEA Bos taurus 357 R-BTA-561072 https://reactome.org/PathwayBrowser/#/R-BTA-561072 OCT3 mediates renal uptake of organic cations IEA Bos taurus 357 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 357 R-CEL-549304 https://reactome.org/PathwayBrowser/#/R-CEL-549304 OCT3 mediates renal clearance of organic cations IEA Caenorhabditis elegans 357 R-CEL-561072 https://reactome.org/PathwayBrowser/#/R-CEL-561072 OCT3 mediates renal uptake of organic cations IEA Caenorhabditis elegans 357 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 357 R-CFA-549304 https://reactome.org/PathwayBrowser/#/R-CFA-549304 OCT3 mediates renal clearance of organic cations IEA Canis familiaris 357 R-CFA-561072 https://reactome.org/PathwayBrowser/#/R-CFA-561072 OCT3 mediates renal uptake of organic cations IEA Canis familiaris 357 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 357 R-DME-549304 https://reactome.org/PathwayBrowser/#/R-DME-549304 OCT3 mediates renal clearance of organic cations IEA Drosophila melanogaster 357 R-DME-561072 https://reactome.org/PathwayBrowser/#/R-DME-561072 OCT3 mediates renal uptake of organic cations IEA Drosophila melanogaster 357 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 357 R-DRE-549304 https://reactome.org/PathwayBrowser/#/R-DRE-549304 OCT3 mediates renal clearance of organic cations IEA Danio rerio 357 R-DRE-561072 https://reactome.org/PathwayBrowser/#/R-DRE-561072 OCT3 mediates renal uptake of organic cations IEA Danio rerio 357 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 357 R-GGA-549304 https://reactome.org/PathwayBrowser/#/R-GGA-549304 OCT3 mediates renal clearance of organic cations IEA Gallus gallus 357 R-GGA-561072 https://reactome.org/PathwayBrowser/#/R-GGA-561072 OCT3 mediates renal uptake of organic cations IEA Gallus gallus 357 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 357 R-HSA-549304 https://reactome.org/PathwayBrowser/#/R-HSA-549304 OCT3 mediates renal clearance of organic cations TAS Homo sapiens 357 R-HSA-561072 https://reactome.org/PathwayBrowser/#/R-HSA-561072 OCT3 mediates renal uptake of organic cations TAS Homo sapiens 357 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 357 R-MMU-549304 https://reactome.org/PathwayBrowser/#/R-MMU-549304 OCT3 mediates renal clearance of organic cations IEA Mus musculus 357 R-MMU-561072 https://reactome.org/PathwayBrowser/#/R-MMU-561072 OCT3 mediates renal uptake of organic cations IEA Mus musculus 357 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 357 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 357 R-RNO-549304 https://reactome.org/PathwayBrowser/#/R-RNO-549304 OCT3 mediates renal clearance of organic cations IEA Rattus norvegicus 357 R-RNO-561072 https://reactome.org/PathwayBrowser/#/R-RNO-561072 OCT3 mediates renal uptake of organic cations IEA Rattus norvegicus 357 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 357 R-SSC-549304 https://reactome.org/PathwayBrowser/#/R-SSC-549304 OCT3 mediates renal clearance of organic cations IEA Sus scrofa 357 R-SSC-561072 https://reactome.org/PathwayBrowser/#/R-SSC-561072 OCT3 mediates renal uptake of organic cations IEA Sus scrofa 357 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 357 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 359 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 359 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 359 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 359 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 359 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 359 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 359 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 359 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 359 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 359 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 359 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 36 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 36 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 36 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 36 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 36 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 36 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 36 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 36 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 36 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 36 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 360 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 360 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 360 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 360 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 360 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 360 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 360 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 360 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 360 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 360 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 360 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 3622 R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 3622 R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 3622 R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 3622 R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 3622 R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 3622 R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 3622 R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 3622 R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 3634 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 3634 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 3634 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 3634 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 3634 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 3634 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 3634 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 3634 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 3634 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 3634 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 3634 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 3634 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 3634 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 3634 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 3634 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 3634 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 3634 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 3634 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 3634 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 3634 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 3635 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 3635 R-BTA-517536 https://reactome.org/PathwayBrowser/#/R-BTA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Bos taurus 3635 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 3635 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 3635 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 3635 R-CFA-517536 https://reactome.org/PathwayBrowser/#/R-CFA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Canis familiaris 3635 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 3635 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 3635 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 3635 R-GGA-517536 https://reactome.org/PathwayBrowser/#/R-GGA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Gallus gallus 3635 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 3635 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 3635 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 3635 R-HSA-517536 https://reactome.org/PathwayBrowser/#/R-HSA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine TAS Homo sapiens 3635 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 3635 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 3635 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 3635 R-MMU-517536 https://reactome.org/PathwayBrowser/#/R-MMU-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Mus musculus 3635 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 3635 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 3635 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 3635 R-RNO-517536 https://reactome.org/PathwayBrowser/#/R-RNO-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Rattus norvegicus 3635 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 3635 R-SSC-517536 https://reactome.org/PathwayBrowser/#/R-SSC-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Sus scrofa 3635 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 3635 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 3635 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 3635 R-XTR-517536 https://reactome.org/PathwayBrowser/#/R-XTR-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine IEA Xenopus tropicalis 3635 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 3635 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 366 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 366 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 366 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 366 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 366 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 366 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 366 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 366 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 366 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 366 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 366 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 367 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 367 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 367 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 367 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 367 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 367 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 367 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 367 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 367 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 367 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 367 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 37 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 37 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 37 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 37 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 37 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 37 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 37 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 37 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 37 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 37 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 38 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 38 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 38 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 38 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 38 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 38 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 38 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 38 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 38 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 38 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 38 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 38 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 38 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 38 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 38 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 38 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 38 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 38 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 38 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 38 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 38 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 38 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 38 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 38 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 38 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 38 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 38 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 38 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 3860 R-BTA-9718360 https://reactome.org/PathwayBrowser/#/R-BTA-9718360 GNRHR binds GNRHR peptide agonists IEA Bos taurus 3860 R-CEL-9718360 https://reactome.org/PathwayBrowser/#/R-CEL-9718360 GNRHR binds GNRHR peptide agonists IEA Caenorhabditis elegans 3860 R-CFA-9718360 https://reactome.org/PathwayBrowser/#/R-CFA-9718360 GNRHR binds GNRHR peptide agonists IEA Canis familiaris 3860 R-DME-9718360 https://reactome.org/PathwayBrowser/#/R-DME-9718360 GNRHR binds GNRHR peptide agonists IEA Drosophila melanogaster 3860 R-DRE-9718360 https://reactome.org/PathwayBrowser/#/R-DRE-9718360 GNRHR binds GNRHR peptide agonists IEA Danio rerio 3860 R-GGA-9718360 https://reactome.org/PathwayBrowser/#/R-GGA-9718360 GNRHR binds GNRHR peptide agonists IEA Gallus gallus 3860 R-HSA-9718360 https://reactome.org/PathwayBrowser/#/R-HSA-9718360 GNRHR binds GNRHR peptide agonists TAS Homo sapiens 3860 R-MMU-9718360 https://reactome.org/PathwayBrowser/#/R-MMU-9718360 GNRHR binds GNRHR peptide agonists IEA Mus musculus 3860 R-RNO-9718360 https://reactome.org/PathwayBrowser/#/R-RNO-9718360 GNRHR binds GNRHR peptide agonists IEA Rattus norvegicus 3860 R-SSC-9718360 https://reactome.org/PathwayBrowser/#/R-SSC-9718360 GNRHR binds GNRHR peptide agonists IEA Sus scrofa 3860 R-XTR-9718360 https://reactome.org/PathwayBrowser/#/R-XTR-9718360 GNRHR binds GNRHR peptide agonists IEA Xenopus tropicalis 3877 R-BTA-9718394 https://reactome.org/PathwayBrowser/#/R-BTA-9718394 GNRHR binds GNRHR peptide antagonists IEA Bos taurus 3877 R-CEL-9718394 https://reactome.org/PathwayBrowser/#/R-CEL-9718394 GNRHR binds GNRHR peptide antagonists IEA Caenorhabditis elegans 3877 R-CFA-9718394 https://reactome.org/PathwayBrowser/#/R-CFA-9718394 GNRHR binds GNRHR peptide antagonists IEA Canis familiaris 3877 R-DME-9718394 https://reactome.org/PathwayBrowser/#/R-DME-9718394 GNRHR binds GNRHR peptide antagonists IEA Drosophila melanogaster 3877 R-DRE-9718394 https://reactome.org/PathwayBrowser/#/R-DRE-9718394 GNRHR binds GNRHR peptide antagonists IEA Danio rerio 3877 R-GGA-9718394 https://reactome.org/PathwayBrowser/#/R-GGA-9718394 GNRHR binds GNRHR peptide antagonists IEA Gallus gallus 3877 R-HSA-9718394 https://reactome.org/PathwayBrowser/#/R-HSA-9718394 GNRHR binds GNRHR peptide antagonists TAS Homo sapiens 3877 R-MMU-9718394 https://reactome.org/PathwayBrowser/#/R-MMU-9718394 GNRHR binds GNRHR peptide antagonists IEA Mus musculus 3877 R-RNO-9718394 https://reactome.org/PathwayBrowser/#/R-RNO-9718394 GNRHR binds GNRHR peptide antagonists IEA Rattus norvegicus 3877 R-SSC-9718394 https://reactome.org/PathwayBrowser/#/R-SSC-9718394 GNRHR binds GNRHR peptide antagonists IEA Sus scrofa 3877 R-XTR-9718394 https://reactome.org/PathwayBrowser/#/R-XTR-9718394 GNRHR binds GNRHR peptide antagonists IEA Xenopus tropicalis 3879 R-BTA-9718360 https://reactome.org/PathwayBrowser/#/R-BTA-9718360 GNRHR binds GNRHR peptide agonists IEA Bos taurus 3879 R-CEL-9718360 https://reactome.org/PathwayBrowser/#/R-CEL-9718360 GNRHR binds GNRHR peptide agonists IEA Caenorhabditis elegans 3879 R-CFA-9718360 https://reactome.org/PathwayBrowser/#/R-CFA-9718360 GNRHR binds GNRHR peptide agonists IEA Canis familiaris 3879 R-DME-9718360 https://reactome.org/PathwayBrowser/#/R-DME-9718360 GNRHR binds GNRHR peptide agonists IEA Drosophila melanogaster 3879 R-DRE-9718360 https://reactome.org/PathwayBrowser/#/R-DRE-9718360 GNRHR binds GNRHR peptide agonists IEA Danio rerio 3879 R-GGA-9718360 https://reactome.org/PathwayBrowser/#/R-GGA-9718360 GNRHR binds GNRHR peptide agonists IEA Gallus gallus 3879 R-HSA-9718360 https://reactome.org/PathwayBrowser/#/R-HSA-9718360 GNRHR binds GNRHR peptide agonists TAS Homo sapiens 3879 R-MMU-9718360 https://reactome.org/PathwayBrowser/#/R-MMU-9718360 GNRHR binds GNRHR peptide agonists IEA Mus musculus 3879 R-RNO-9718360 https://reactome.org/PathwayBrowser/#/R-RNO-9718360 GNRHR binds GNRHR peptide agonists IEA Rattus norvegicus 3879 R-SSC-9718360 https://reactome.org/PathwayBrowser/#/R-SSC-9718360 GNRHR binds GNRHR peptide agonists IEA Sus scrofa 3879 R-XTR-9718360 https://reactome.org/PathwayBrowser/#/R-XTR-9718360 GNRHR binds GNRHR peptide agonists IEA Xenopus tropicalis 3884 R-BTA-9718360 https://reactome.org/PathwayBrowser/#/R-BTA-9718360 GNRHR binds GNRHR peptide agonists IEA Bos taurus 3884 R-CEL-9718360 https://reactome.org/PathwayBrowser/#/R-CEL-9718360 GNRHR binds GNRHR peptide agonists IEA Caenorhabditis elegans 3884 R-CFA-9718360 https://reactome.org/PathwayBrowser/#/R-CFA-9718360 GNRHR binds GNRHR peptide agonists IEA Canis familiaris 3884 R-DME-9718360 https://reactome.org/PathwayBrowser/#/R-DME-9718360 GNRHR binds GNRHR peptide agonists IEA Drosophila melanogaster 3884 R-DRE-9718360 https://reactome.org/PathwayBrowser/#/R-DRE-9718360 GNRHR binds GNRHR peptide agonists IEA Danio rerio 3884 R-GGA-9718360 https://reactome.org/PathwayBrowser/#/R-GGA-9718360 GNRHR binds GNRHR peptide agonists IEA Gallus gallus 3884 R-HSA-9718360 https://reactome.org/PathwayBrowser/#/R-HSA-9718360 GNRHR binds GNRHR peptide agonists TAS Homo sapiens 3884 R-MMU-9718360 https://reactome.org/PathwayBrowser/#/R-MMU-9718360 GNRHR binds GNRHR peptide agonists IEA Mus musculus 3884 R-RNO-9718360 https://reactome.org/PathwayBrowser/#/R-RNO-9718360 GNRHR binds GNRHR peptide agonists IEA Rattus norvegicus 3884 R-SSC-9718360 https://reactome.org/PathwayBrowser/#/R-SSC-9718360 GNRHR binds GNRHR peptide agonists IEA Sus scrofa 3884 R-XTR-9718360 https://reactome.org/PathwayBrowser/#/R-XTR-9718360 GNRHR binds GNRHR peptide agonists IEA Xenopus tropicalis 3902 R-BTA-9718360 https://reactome.org/PathwayBrowser/#/R-BTA-9718360 GNRHR binds GNRHR peptide agonists IEA Bos taurus 3902 R-CEL-9718360 https://reactome.org/PathwayBrowser/#/R-CEL-9718360 GNRHR binds GNRHR peptide agonists IEA Caenorhabditis elegans 3902 R-CFA-9718360 https://reactome.org/PathwayBrowser/#/R-CFA-9718360 GNRHR binds GNRHR peptide agonists IEA Canis familiaris 3902 R-DME-9718360 https://reactome.org/PathwayBrowser/#/R-DME-9718360 GNRHR binds GNRHR peptide agonists IEA Drosophila melanogaster 3902 R-DRE-9718360 https://reactome.org/PathwayBrowser/#/R-DRE-9718360 GNRHR binds GNRHR peptide agonists IEA Danio rerio 3902 R-GGA-9718360 https://reactome.org/PathwayBrowser/#/R-GGA-9718360 GNRHR binds GNRHR peptide agonists IEA Gallus gallus 3902 R-HSA-9718360 https://reactome.org/PathwayBrowser/#/R-HSA-9718360 GNRHR binds GNRHR peptide agonists TAS Homo sapiens 3902 R-MMU-9718360 https://reactome.org/PathwayBrowser/#/R-MMU-9718360 GNRHR binds GNRHR peptide agonists IEA Mus musculus 3902 R-RNO-9718360 https://reactome.org/PathwayBrowser/#/R-RNO-9718360 GNRHR binds GNRHR peptide agonists IEA Rattus norvegicus 3902 R-SSC-9718360 https://reactome.org/PathwayBrowser/#/R-SSC-9718360 GNRHR binds GNRHR peptide agonists IEA Sus scrofa 3902 R-XTR-9718360 https://reactome.org/PathwayBrowser/#/R-XTR-9718360 GNRHR binds GNRHR peptide agonists IEA Xenopus tropicalis 3937 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(25-32) binds to AGTR1 IEA Bos taurus 3937 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGTR1 IEA Bos taurus 3937 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(25-32) binds to AGTR1 IEA Caenorhabditis elegans 3937 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGTR1 IEA Caenorhabditis elegans 3937 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(25-32) binds to AGTR1 IEA Canis familiaris 3937 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGTR1 IEA Canis familiaris 3937 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(25-32) binds to AGTR1 IEA Drosophila melanogaster 3937 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGTR1 IEA Drosophila melanogaster 3937 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(25-32) binds to AGTR1 IEA Danio rerio 3937 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGTR1 IEA Danio rerio 3937 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(25-32) binds to AGTR1 IEA Gallus gallus 3937 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGTR1 IEA Gallus gallus 3937 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(25-32) binds to AGTR1 TAS Homo sapiens 3937 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGTR1 TAS Homo sapiens 3937 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(25-32) binds to AGTR1 IEA Mus musculus 3937 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGTR1 IEA Mus musculus 3937 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(25-32) binds to AGTR1 IEA Rattus norvegicus 3937 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGTR1 IEA Rattus norvegicus 3937 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(25-32) binds to AGTR1 IEA Sus scrofa 3937 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGTR1 IEA Sus scrofa 3950 R-BTA-9731931 https://reactome.org/PathwayBrowser/#/R-BTA-9731931 EDNRA binds selective ERAs IEA Bos taurus 3950 R-CFA-9731931 https://reactome.org/PathwayBrowser/#/R-CFA-9731931 EDNRA binds selective ERAs IEA Canis familiaris 3950 R-DRE-9731931 https://reactome.org/PathwayBrowser/#/R-DRE-9731931 EDNRA binds selective ERAs IEA Danio rerio 3950 R-GGA-9731931 https://reactome.org/PathwayBrowser/#/R-GGA-9731931 EDNRA binds selective ERAs IEA Gallus gallus 3950 R-HSA-9731931 https://reactome.org/PathwayBrowser/#/R-HSA-9731931 EDNRA binds selective ERAs TAS Homo sapiens 3950 R-MMU-9731931 https://reactome.org/PathwayBrowser/#/R-MMU-9731931 EDNRA binds selective ERAs IEA Mus musculus 3950 R-RNO-9731931 https://reactome.org/PathwayBrowser/#/R-RNO-9731931 EDNRA binds selective ERAs IEA Rattus norvegicus 3950 R-SSC-9731931 https://reactome.org/PathwayBrowser/#/R-SSC-9731931 EDNRA binds selective ERAs IEA Sus scrofa 3950 R-XTR-9731931 https://reactome.org/PathwayBrowser/#/R-XTR-9731931 EDNRA binds selective ERAs IEA Xenopus tropicalis 3951 R-BTA-9731931 https://reactome.org/PathwayBrowser/#/R-BTA-9731931 EDNRA binds selective ERAs IEA Bos taurus 3951 R-CFA-9731931 https://reactome.org/PathwayBrowser/#/R-CFA-9731931 EDNRA binds selective ERAs IEA Canis familiaris 3951 R-DRE-9731931 https://reactome.org/PathwayBrowser/#/R-DRE-9731931 EDNRA binds selective ERAs IEA Danio rerio 3951 R-GGA-9731931 https://reactome.org/PathwayBrowser/#/R-GGA-9731931 EDNRA binds selective ERAs IEA Gallus gallus 3951 R-HSA-9731931 https://reactome.org/PathwayBrowser/#/R-HSA-9731931 EDNRA binds selective ERAs TAS Homo sapiens 3951 R-MMU-9731931 https://reactome.org/PathwayBrowser/#/R-MMU-9731931 EDNRA binds selective ERAs IEA Mus musculus 3951 R-RNO-9731931 https://reactome.org/PathwayBrowser/#/R-RNO-9731931 EDNRA binds selective ERAs IEA Rattus norvegicus 3951 R-SSC-9731931 https://reactome.org/PathwayBrowser/#/R-SSC-9731931 EDNRA binds selective ERAs IEA Sus scrofa 3951 R-XTR-9731931 https://reactome.org/PathwayBrowser/#/R-XTR-9731931 EDNRA binds selective ERAs IEA Xenopus tropicalis 40 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 40 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 40 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 40 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 40 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 40 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 40 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 40 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 40 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 40 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 4047 R-BTA-9708866 https://reactome.org/PathwayBrowser/#/R-BTA-9708866 pro-F2R binds vorapaxar IEA Bos taurus 4047 R-CEL-9708866 https://reactome.org/PathwayBrowser/#/R-CEL-9708866 pro-F2R binds vorapaxar IEA Caenorhabditis elegans 4047 R-CFA-9708866 https://reactome.org/PathwayBrowser/#/R-CFA-9708866 pro-F2R binds vorapaxar IEA Canis familiaris 4047 R-DRE-9708866 https://reactome.org/PathwayBrowser/#/R-DRE-9708866 pro-F2R binds vorapaxar IEA Danio rerio 4047 R-GGA-9708866 https://reactome.org/PathwayBrowser/#/R-GGA-9708866 pro-F2R binds vorapaxar IEA Gallus gallus 4047 R-HSA-9708866 https://reactome.org/PathwayBrowser/#/R-HSA-9708866 pro-F2R binds vorapaxar TAS Homo sapiens 4047 R-MMU-9708866 https://reactome.org/PathwayBrowser/#/R-MMU-9708866 pro-F2R binds vorapaxar IEA Mus musculus 4047 R-RNO-9708866 https://reactome.org/PathwayBrowser/#/R-RNO-9708866 pro-F2R binds vorapaxar IEA Rattus norvegicus 4047 R-SSC-9708866 https://reactome.org/PathwayBrowser/#/R-SSC-9708866 pro-F2R binds vorapaxar IEA Sus scrofa 4047 R-XTR-9708866 https://reactome.org/PathwayBrowser/#/R-XTR-9708866 pro-F2R binds vorapaxar IEA Xenopus tropicalis 4053 R-BTA-2404134 https://reactome.org/PathwayBrowser/#/R-BTA-2404134 RBP4:atROL binds TTR IEA Bos taurus 4053 R-BTA-2404135 https://reactome.org/PathwayBrowser/#/R-BTA-2404135 RBP4 binds atROL IEA Bos taurus 4053 R-BTA-2404137 https://reactome.org/PathwayBrowser/#/R-BTA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 4053 R-BTA-2404142 https://reactome.org/PathwayBrowser/#/R-BTA-2404142 atROL binds RBP1 IEA Bos taurus 4053 R-BTA-2404144 https://reactome.org/PathwayBrowser/#/R-BTA-2404144 Parenchymal atROL translocates to HSCs IEA Bos taurus 4053 R-BTA-2453855 https://reactome.org/PathwayBrowser/#/R-BTA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Bos taurus 4053 R-BTA-2453863 https://reactome.org/PathwayBrowser/#/R-BTA-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Bos taurus 4053 R-BTA-2453876 https://reactome.org/PathwayBrowser/#/R-BTA-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Bos taurus 4053 R-BTA-2464776 https://reactome.org/PathwayBrowser/#/R-BTA-2464776 Rdh8 reduces atRAL to atROL TAS Bos taurus 4053 R-BTA-2464809 https://reactome.org/PathwayBrowser/#/R-BTA-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Bos taurus 4053 R-BTA-2464822 https://reactome.org/PathwayBrowser/#/R-BTA-2464822 RDH12 reduces atRAL to atROL IEA Bos taurus 4053 R-BTA-2465938 https://reactome.org/PathwayBrowser/#/R-BTA-2465938 RBP3 regulates atROL taken up by Muller cells IEA Bos taurus 4053 R-BTA-2465940 https://reactome.org/PathwayBrowser/#/R-BTA-2465940 atRAL is reduced to atROL IEA Bos taurus 4053 R-BTA-2465971 https://reactome.org/PathwayBrowser/#/R-BTA-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Bos taurus 4053 R-BTA-2855252 https://reactome.org/PathwayBrowser/#/R-BTA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Bos taurus 4053 R-BTA-2855259 https://reactome.org/PathwayBrowser/#/R-BTA-2855259 atROL binds RBP1 (parenchymal cell) IEA Bos taurus 4053 R-BTA-5246478 https://reactome.org/PathwayBrowser/#/R-BTA-5246478 APOM binds retinoids IEA Bos taurus 4053 R-BTA-5362518 https://reactome.org/PathwayBrowser/#/R-BTA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Bos taurus 4053 R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 4053 R-BTA-5419165 https://reactome.org/PathwayBrowser/#/R-BTA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Bos taurus 4053 R-BTA-5615668 https://reactome.org/PathwayBrowser/#/R-BTA-5615668 AKR1C3 reduces atRAL to atROL IEA Bos taurus 4053 R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 4053 R-BTA-74843 https://reactome.org/PathwayBrowser/#/R-BTA-74843 atROL binds RBP1 to form RBP1:atROL IEA Bos taurus 4053 R-BTA-8848355 https://reactome.org/PathwayBrowser/#/R-BTA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Bos taurus 4053 R-BTA-8848585 https://reactome.org/PathwayBrowser/#/R-BTA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Bos taurus 4053 R-BTA-975593 https://reactome.org/PathwayBrowser/#/R-BTA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Bos taurus 4053 R-BTA-975594 https://reactome.org/PathwayBrowser/#/R-BTA-975594 PLB1 hydrolyses RPALM to atROL IEA Bos taurus 4053 R-BTA-975608 https://reactome.org/PathwayBrowser/#/R-BTA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Bos taurus 4053 R-BTA-975629 https://reactome.org/PathwayBrowser/#/R-BTA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Bos taurus 4053 R-BTA-975633 https://reactome.org/PathwayBrowser/#/R-BTA-975633 atROL binds to RBP2 IEA Bos taurus 4053 R-CEL-2404134 https://reactome.org/PathwayBrowser/#/R-CEL-2404134 RBP4:atROL binds TTR IEA Caenorhabditis elegans 4053 R-CEL-2404135 https://reactome.org/PathwayBrowser/#/R-CEL-2404135 RBP4 binds atROL IEA Caenorhabditis elegans 4053 R-CEL-2404142 https://reactome.org/PathwayBrowser/#/R-CEL-2404142 atROL binds RBP1 IEA Caenorhabditis elegans 4053 R-CEL-2404144 https://reactome.org/PathwayBrowser/#/R-CEL-2404144 Parenchymal atROL translocates to HSCs IEA Caenorhabditis elegans 4053 R-CEL-2465940 https://reactome.org/PathwayBrowser/#/R-CEL-2465940 atRAL is reduced to atROL IEA Caenorhabditis elegans 4053 R-CEL-2855252 https://reactome.org/PathwayBrowser/#/R-CEL-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Caenorhabditis elegans 4053 R-CEL-2855259 https://reactome.org/PathwayBrowser/#/R-CEL-2855259 atROL binds RBP1 (parenchymal cell) IEA Caenorhabditis elegans 4053 R-CEL-5362518 https://reactome.org/PathwayBrowser/#/R-CEL-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Caenorhabditis elegans 4053 R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 4053 R-CEL-5419165 https://reactome.org/PathwayBrowser/#/R-CEL-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Caenorhabditis elegans 4053 R-CEL-5615668 https://reactome.org/PathwayBrowser/#/R-CEL-5615668 AKR1C3 reduces atRAL to atROL IEA Caenorhabditis elegans 4053 R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 4053 R-CEL-74843 https://reactome.org/PathwayBrowser/#/R-CEL-74843 atROL binds RBP1 to form RBP1:atROL IEA Caenorhabditis elegans 4053 R-CEL-8848585 https://reactome.org/PathwayBrowser/#/R-CEL-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Caenorhabditis elegans 4053 R-CEL-975594 https://reactome.org/PathwayBrowser/#/R-CEL-975594 PLB1 hydrolyses RPALM to atROL IEA Caenorhabditis elegans 4053 R-CEL-975633 https://reactome.org/PathwayBrowser/#/R-CEL-975633 atROL binds to RBP2 IEA Caenorhabditis elegans 4053 R-CFA-2404134 https://reactome.org/PathwayBrowser/#/R-CFA-2404134 RBP4:atROL binds TTR IEA Canis familiaris 4053 R-CFA-2404135 https://reactome.org/PathwayBrowser/#/R-CFA-2404135 RBP4 binds atROL IEA Canis familiaris 4053 R-CFA-2404137 https://reactome.org/PathwayBrowser/#/R-CFA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 4053 R-CFA-2404142 https://reactome.org/PathwayBrowser/#/R-CFA-2404142 atROL binds RBP1 IEA Canis familiaris 4053 R-CFA-2404144 https://reactome.org/PathwayBrowser/#/R-CFA-2404144 Parenchymal atROL translocates to HSCs IEA Canis familiaris 4053 R-CFA-2453855 https://reactome.org/PathwayBrowser/#/R-CFA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Canis familiaris 4053 R-CFA-2453863 https://reactome.org/PathwayBrowser/#/R-CFA-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Canis familiaris 4053 R-CFA-2453876 https://reactome.org/PathwayBrowser/#/R-CFA-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Canis familiaris 4053 R-CFA-2464809 https://reactome.org/PathwayBrowser/#/R-CFA-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Canis familiaris 4053 R-CFA-2464822 https://reactome.org/PathwayBrowser/#/R-CFA-2464822 RDH12 reduces atRAL to atROL IEA Canis familiaris 4053 R-CFA-2465938 https://reactome.org/PathwayBrowser/#/R-CFA-2465938 RBP3 regulates atROL taken up by Muller cells IEA Canis familiaris 4053 R-CFA-2465940 https://reactome.org/PathwayBrowser/#/R-CFA-2465940 atRAL is reduced to atROL IEA Canis familiaris 4053 R-CFA-2465971 https://reactome.org/PathwayBrowser/#/R-CFA-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Canis familiaris 4053 R-CFA-2855259 https://reactome.org/PathwayBrowser/#/R-CFA-2855259 atROL binds RBP1 (parenchymal cell) IEA Canis familiaris 4053 R-CFA-5246478 https://reactome.org/PathwayBrowser/#/R-CFA-5246478 APOM binds retinoids IEA Canis familiaris 4053 R-CFA-5362518 https://reactome.org/PathwayBrowser/#/R-CFA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Canis familiaris 4053 R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 4053 R-CFA-5419165 https://reactome.org/PathwayBrowser/#/R-CFA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Canis familiaris 4053 R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 4053 R-CFA-74843 https://reactome.org/PathwayBrowser/#/R-CFA-74843 atROL binds RBP1 to form RBP1:atROL IEA Canis familiaris 4053 R-CFA-8848355 https://reactome.org/PathwayBrowser/#/R-CFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Canis familiaris 4053 R-CFA-8848585 https://reactome.org/PathwayBrowser/#/R-CFA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Canis familiaris 4053 R-CFA-975594 https://reactome.org/PathwayBrowser/#/R-CFA-975594 PLB1 hydrolyses RPALM to atROL IEA Canis familiaris 4053 R-CFA-975608 https://reactome.org/PathwayBrowser/#/R-CFA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Canis familiaris 4053 R-CFA-975633 https://reactome.org/PathwayBrowser/#/R-CFA-975633 atROL binds to RBP2 IEA Canis familiaris 4053 R-DDI-2465971 https://reactome.org/PathwayBrowser/#/R-DDI-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Dictyostelium discoideum 4053 R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 4053 R-DDI-5419165 https://reactome.org/PathwayBrowser/#/R-DDI-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Dictyostelium discoideum 4053 R-DDI-5615668 https://reactome.org/PathwayBrowser/#/R-DDI-5615668 AKR1C3 reduces atRAL to atROL IEA Dictyostelium discoideum 4053 R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 4053 R-DDI-8848585 https://reactome.org/PathwayBrowser/#/R-DDI-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Dictyostelium discoideum 4053 R-DME-2404142 https://reactome.org/PathwayBrowser/#/R-DME-2404142 atROL binds RBP1 IEA Drosophila melanogaster 4053 R-DME-2404144 https://reactome.org/PathwayBrowser/#/R-DME-2404144 Parenchymal atROL translocates to HSCs IEA Drosophila melanogaster 4053 R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster 4053 R-DME-2465940 https://reactome.org/PathwayBrowser/#/R-DME-2465940 atRAL is reduced to atROL IEA Drosophila melanogaster 4053 R-DME-2465971 https://reactome.org/PathwayBrowser/#/R-DME-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Drosophila melanogaster 4053 R-DME-2855252 https://reactome.org/PathwayBrowser/#/R-DME-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 4053 R-DME-2855259 https://reactome.org/PathwayBrowser/#/R-DME-2855259 atROL binds RBP1 (parenchymal cell) IEA Drosophila melanogaster 4053 R-DME-5362518 https://reactome.org/PathwayBrowser/#/R-DME-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Drosophila melanogaster 4053 R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 4053 R-DME-5419165 https://reactome.org/PathwayBrowser/#/R-DME-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Drosophila melanogaster 4053 R-DME-5615668 https://reactome.org/PathwayBrowser/#/R-DME-5615668 AKR1C3 reduces atRAL to atROL IEA Drosophila melanogaster 4053 R-DME-74843 https://reactome.org/PathwayBrowser/#/R-DME-74843 atROL binds RBP1 to form RBP1:atROL IEA Drosophila melanogaster 4053 R-DME-8848585 https://reactome.org/PathwayBrowser/#/R-DME-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Drosophila melanogaster 4053 R-DME-975594 https://reactome.org/PathwayBrowser/#/R-DME-975594 PLB1 hydrolyses RPALM to atROL IEA Drosophila melanogaster 4053 R-DME-975629 https://reactome.org/PathwayBrowser/#/R-DME-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 4053 R-DME-975633 https://reactome.org/PathwayBrowser/#/R-DME-975633 atROL binds to RBP2 IEA Drosophila melanogaster 4053 R-DRE-2404135 https://reactome.org/PathwayBrowser/#/R-DRE-2404135 RBP4 binds atROL IEA Danio rerio 4053 R-DRE-2404137 https://reactome.org/PathwayBrowser/#/R-DRE-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 4053 R-DRE-2404142 https://reactome.org/PathwayBrowser/#/R-DRE-2404142 atROL binds RBP1 IEA Danio rerio 4053 R-DRE-2404144 https://reactome.org/PathwayBrowser/#/R-DRE-2404144 Parenchymal atROL translocates to HSCs IEA Danio rerio 4053 R-DRE-2453855 https://reactome.org/PathwayBrowser/#/R-DRE-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Danio rerio 4053 R-DRE-2464822 https://reactome.org/PathwayBrowser/#/R-DRE-2464822 RDH12 reduces atRAL to atROL IEA Danio rerio 4053 R-DRE-2465940 https://reactome.org/PathwayBrowser/#/R-DRE-2465940 atRAL is reduced to atROL IEA Danio rerio 4053 R-DRE-2465971 https://reactome.org/PathwayBrowser/#/R-DRE-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Danio rerio 4053 R-DRE-2855252 https://reactome.org/PathwayBrowser/#/R-DRE-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Danio rerio 4053 R-DRE-2855259 https://reactome.org/PathwayBrowser/#/R-DRE-2855259 atROL binds RBP1 (parenchymal cell) IEA Danio rerio 4053 R-DRE-5362518 https://reactome.org/PathwayBrowser/#/R-DRE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Danio rerio 4053 R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 4053 R-DRE-5419165 https://reactome.org/PathwayBrowser/#/R-DRE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Danio rerio 4053 R-DRE-74843 https://reactome.org/PathwayBrowser/#/R-DRE-74843 atROL binds RBP1 to form RBP1:atROL IEA Danio rerio 4053 R-DRE-8848585 https://reactome.org/PathwayBrowser/#/R-DRE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Danio rerio 4053 R-DRE-975608 https://reactome.org/PathwayBrowser/#/R-DRE-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Danio rerio 4053 R-DRE-975629 https://reactome.org/PathwayBrowser/#/R-DRE-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Danio rerio 4053 R-DRE-975633 https://reactome.org/PathwayBrowser/#/R-DRE-975633 atROL binds to RBP2 IEA Danio rerio 4053 R-GGA-2404134 https://reactome.org/PathwayBrowser/#/R-GGA-2404134 RBP4:atROL binds TTR IEA Gallus gallus 4053 R-GGA-2404135 https://reactome.org/PathwayBrowser/#/R-GGA-2404135 RBP4 binds atROL IEA Gallus gallus 4053 R-GGA-2404137 https://reactome.org/PathwayBrowser/#/R-GGA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 4053 R-GGA-2404142 https://reactome.org/PathwayBrowser/#/R-GGA-2404142 atROL binds RBP1 IEA Gallus gallus 4053 R-GGA-2404144 https://reactome.org/PathwayBrowser/#/R-GGA-2404144 Parenchymal atROL translocates to HSCs IEA Gallus gallus 4053 R-GGA-2453855 https://reactome.org/PathwayBrowser/#/R-GGA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Gallus gallus 4053 R-GGA-2453863 https://reactome.org/PathwayBrowser/#/R-GGA-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Gallus gallus 4053 R-GGA-2453876 https://reactome.org/PathwayBrowser/#/R-GGA-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Gallus gallus 4053 R-GGA-2464809 https://reactome.org/PathwayBrowser/#/R-GGA-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Gallus gallus 4053 R-GGA-2464822 https://reactome.org/PathwayBrowser/#/R-GGA-2464822 RDH12 reduces atRAL to atROL IEA Gallus gallus 4053 R-GGA-2465929 https://reactome.org/PathwayBrowser/#/R-GGA-2465929 Isomerase II isomerises atROL to 11cROL TAS Gallus gallus 4053 R-GGA-2465938 https://reactome.org/PathwayBrowser/#/R-GGA-2465938 RBP3 regulates atROL taken up by Muller cells IEA Gallus gallus 4053 R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus 4053 R-GGA-2465971 https://reactome.org/PathwayBrowser/#/R-GGA-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Gallus gallus 4053 R-GGA-2855252 https://reactome.org/PathwayBrowser/#/R-GGA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Gallus gallus 4053 R-GGA-2855259 https://reactome.org/PathwayBrowser/#/R-GGA-2855259 atROL binds RBP1 (parenchymal cell) IEA Gallus gallus 4053 R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus 4053 R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 4053 R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus 4053 R-GGA-74843 https://reactome.org/PathwayBrowser/#/R-GGA-74843 atROL binds RBP1 to form RBP1:atROL IEA Gallus gallus 4053 R-GGA-8848355 https://reactome.org/PathwayBrowser/#/R-GGA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Gallus gallus 4053 R-GGA-8848585 https://reactome.org/PathwayBrowser/#/R-GGA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Gallus gallus 4053 R-GGA-975593 https://reactome.org/PathwayBrowser/#/R-GGA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Gallus gallus 4053 R-GGA-975594 https://reactome.org/PathwayBrowser/#/R-GGA-975594 PLB1 hydrolyses RPALM to atROL IEA Gallus gallus 4053 R-GGA-975608 https://reactome.org/PathwayBrowser/#/R-GGA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Gallus gallus 4053 R-GGA-975629 https://reactome.org/PathwayBrowser/#/R-GGA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Gallus gallus 4053 R-GGA-975633 https://reactome.org/PathwayBrowser/#/R-GGA-975633 atROL binds to RBP2 IEA Gallus gallus 4053 R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 4053 R-HSA-2404134 https://reactome.org/PathwayBrowser/#/R-HSA-2404134 RBP4:atROL binds TTR TAS Homo sapiens 4053 R-HSA-2404135 https://reactome.org/PathwayBrowser/#/R-HSA-2404135 RBP4 binds atROL TAS Homo sapiens 4053 R-HSA-2404137 https://reactome.org/PathwayBrowser/#/R-HSA-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 4053 R-HSA-2404139 https://reactome.org/PathwayBrowser/#/R-HSA-2404139 HSC cytosolic atROL translocates to extracellular region TAS Homo sapiens 4053 R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 4053 R-HSA-2404142 https://reactome.org/PathwayBrowser/#/R-HSA-2404142 atROL binds RBP1 TAS Homo sapiens 4053 R-HSA-2404144 https://reactome.org/PathwayBrowser/#/R-HSA-2404144 Parenchymal atROL translocates to HSCs TAS Homo sapiens 4053 R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 4053 R-HSA-2453818 https://reactome.org/PathwayBrowser/#/R-HSA-2453818 Defective STRA6 does not transport atROL TAS Homo sapiens 4053 R-HSA-2453855 https://reactome.org/PathwayBrowser/#/R-HSA-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs TAS Homo sapiens 4053 R-HSA-2453863 https://reactome.org/PathwayBrowser/#/R-HSA-2453863 STRA6 transports atROL from extracellular region to cytosol TAS Homo sapiens 4053 R-HSA-2453876 https://reactome.org/PathwayBrowser/#/R-HSA-2453876 TTR:RBP:atROL binds to STRA6 receptor TAS Homo sapiens 4053 R-HSA-2464803 https://reactome.org/PathwayBrowser/#/R-HSA-2464803 RDH8 reduces atRAL to atROL IEA Homo sapiens 4053 R-HSA-2464809 https://reactome.org/PathwayBrowser/#/R-HSA-2464809 RBP3 regulates the transport of atROL from ROS to RPE TAS Homo sapiens 4053 R-HSA-2464822 https://reactome.org/PathwayBrowser/#/R-HSA-2464822 RDH12 reduces atRAL to atROL TAS Homo sapiens 4053 R-HSA-2465926 https://reactome.org/PathwayBrowser/#/R-HSA-2465926 An atROL isomerase isomerises atROL to 11cROL IEA Homo sapiens 4053 R-HSA-2465938 https://reactome.org/PathwayBrowser/#/R-HSA-2465938 RBP3 regulates atROL taken up by Muller cells TAS Homo sapiens 4053 R-HSA-2465940 https://reactome.org/PathwayBrowser/#/R-HSA-2465940 atRAL is reduced to atROL TAS Homo sapiens 4053 R-HSA-2465971 https://reactome.org/PathwayBrowser/#/R-HSA-2465971 RLBP1 binds atROL to form RLBP1:atROL TAS Homo sapiens 4053 R-HSA-2466710 https://reactome.org/PathwayBrowser/#/R-HSA-2466710 Defective LRAT does not esterify RBP1:atROL and FACYLs to atREs TAS Homo sapiens 4053 R-HSA-2466828 https://reactome.org/PathwayBrowser/#/R-HSA-2466828 Defective RBP4 does not bind atROL TAS Homo sapiens 4053 R-HSA-2855252 https://reactome.org/PathwayBrowser/#/R-HSA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL TAS Homo sapiens 4053 R-HSA-2855259 https://reactome.org/PathwayBrowser/#/R-HSA-2855259 atROL binds RBP1 (parenchymal cell) TAS Homo sapiens 4053 R-HSA-5246478 https://reactome.org/PathwayBrowser/#/R-HSA-5246478 APOM binds retinoids TAS Homo sapiens 4053 R-HSA-5362518 https://reactome.org/PathwayBrowser/#/R-HSA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL TAS Homo sapiens 4053 R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 4053 R-HSA-5419165 https://reactome.org/PathwayBrowser/#/R-HSA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL TAS Homo sapiens 4053 R-HSA-5615668 https://reactome.org/PathwayBrowser/#/R-HSA-5615668 AKR1C3 reduces atRAL to atROL TAS Homo sapiens 4053 R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 4053 R-HSA-74843 https://reactome.org/PathwayBrowser/#/R-HSA-74843 atROL binds RBP1 to form RBP1:atROL TAS Homo sapiens 4053 R-HSA-8848355 https://reactome.org/PathwayBrowser/#/R-HSA-8848355 PNPLA4 hydrolyzes retinyl palmitate TAS Homo sapiens 4053 R-HSA-8848585 https://reactome.org/PathwayBrowser/#/R-HSA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM TAS Homo sapiens 4053 R-HSA-8956427 https://reactome.org/PathwayBrowser/#/R-HSA-8956427 RETSAT reduces atROL to at-13,14-dhROL IEA Homo sapiens 4053 R-HSA-975593 https://reactome.org/PathwayBrowser/#/R-HSA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM TAS Homo sapiens 4053 R-HSA-975594 https://reactome.org/PathwayBrowser/#/R-HSA-975594 PLB1 hydrolyses RPALM to atROL TAS Homo sapiens 4053 R-HSA-975608 https://reactome.org/PathwayBrowser/#/R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs TAS Homo sapiens 4053 R-HSA-975629 https://reactome.org/PathwayBrowser/#/R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL TAS Homo sapiens 4053 R-HSA-975633 https://reactome.org/PathwayBrowser/#/R-HSA-975633 atROL binds to RBP2 TAS Homo sapiens 4053 R-MMU-2404134 https://reactome.org/PathwayBrowser/#/R-MMU-2404134 RBP4:atROL binds TTR IEA Mus musculus 4053 R-MMU-2404135 https://reactome.org/PathwayBrowser/#/R-MMU-2404135 RBP4 binds atROL IEA Mus musculus 4053 R-MMU-2404137 https://reactome.org/PathwayBrowser/#/R-MMU-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 4053 R-MMU-2404142 https://reactome.org/PathwayBrowser/#/R-MMU-2404142 atROL binds RBP1 IEA Mus musculus 4053 R-MMU-2404144 https://reactome.org/PathwayBrowser/#/R-MMU-2404144 Parenchymal atROL translocates to HSCs IEA Mus musculus 4053 R-MMU-2453855 https://reactome.org/PathwayBrowser/#/R-MMU-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Mus musculus 4053 R-MMU-2453863 https://reactome.org/PathwayBrowser/#/R-MMU-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Mus musculus 4053 R-MMU-2453876 https://reactome.org/PathwayBrowser/#/R-MMU-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Mus musculus 4053 R-MMU-2464809 https://reactome.org/PathwayBrowser/#/R-MMU-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Mus musculus 4053 R-MMU-2464822 https://reactome.org/PathwayBrowser/#/R-MMU-2464822 RDH12 reduces atRAL to atROL IEA Mus musculus 4053 R-MMU-2465938 https://reactome.org/PathwayBrowser/#/R-MMU-2465938 RBP3 regulates atROL taken up by Muller cells IEA Mus musculus 4053 R-MMU-2465940 https://reactome.org/PathwayBrowser/#/R-MMU-2465940 atRAL is reduced to atROL IEA Mus musculus 4053 R-MMU-2465971 https://reactome.org/PathwayBrowser/#/R-MMU-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Mus musculus 4053 R-MMU-2855252 https://reactome.org/PathwayBrowser/#/R-MMU-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Mus musculus 4053 R-MMU-2855259 https://reactome.org/PathwayBrowser/#/R-MMU-2855259 atROL binds RBP1 (parenchymal cell) IEA Mus musculus 4053 R-MMU-5246478 https://reactome.org/PathwayBrowser/#/R-MMU-5246478 APOM binds retinoids IEA Mus musculus 4053 R-MMU-5362518 https://reactome.org/PathwayBrowser/#/R-MMU-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Mus musculus 4053 R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 4053 R-MMU-5419165 https://reactome.org/PathwayBrowser/#/R-MMU-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Mus musculus 4053 R-MMU-5615668 https://reactome.org/PathwayBrowser/#/R-MMU-5615668 AKR1C3 reduces atRAL to atROL IEA Mus musculus 4053 R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 4053 R-MMU-74843 https://reactome.org/PathwayBrowser/#/R-MMU-74843 atROL binds RBP1 to form RBP1:atROL IEA Mus musculus 4053 R-MMU-8848585 https://reactome.org/PathwayBrowser/#/R-MMU-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Mus musculus 4053 R-MMU-8956439 https://reactome.org/PathwayBrowser/#/R-MMU-8956439 Retsat reduces atROL to at-13,14-dhROL TAS Mus musculus 4053 R-MMU-975593 https://reactome.org/PathwayBrowser/#/R-MMU-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Mus musculus 4053 R-MMU-975594 https://reactome.org/PathwayBrowser/#/R-MMU-975594 PLB1 hydrolyses RPALM to atROL IEA Mus musculus 4053 R-MMU-975608 https://reactome.org/PathwayBrowser/#/R-MMU-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Mus musculus 4053 R-MMU-975629 https://reactome.org/PathwayBrowser/#/R-MMU-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Mus musculus 4053 R-MMU-975633 https://reactome.org/PathwayBrowser/#/R-MMU-975633 atROL binds to RBP2 IEA Mus musculus 4053 R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 4053 R-PFA-8848355 https://reactome.org/PathwayBrowser/#/R-PFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Plasmodium falciparum 4053 R-RNO-2404134 https://reactome.org/PathwayBrowser/#/R-RNO-2404134 RBP4:atROL binds TTR IEA Rattus norvegicus 4053 R-RNO-2404135 https://reactome.org/PathwayBrowser/#/R-RNO-2404135 RBP4 binds atROL IEA Rattus norvegicus 4053 R-RNO-2404137 https://reactome.org/PathwayBrowser/#/R-RNO-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 4053 R-RNO-2404142 https://reactome.org/PathwayBrowser/#/R-RNO-2404142 atROL binds RBP1 IEA Rattus norvegicus 4053 R-RNO-2404144 https://reactome.org/PathwayBrowser/#/R-RNO-2404144 Parenchymal atROL translocates to HSCs IEA Rattus norvegicus 4053 R-RNO-2453855 https://reactome.org/PathwayBrowser/#/R-RNO-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Rattus norvegicus 4053 R-RNO-2453863 https://reactome.org/PathwayBrowser/#/R-RNO-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Rattus norvegicus 4053 R-RNO-2453876 https://reactome.org/PathwayBrowser/#/R-RNO-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Rattus norvegicus 4053 R-RNO-2464809 https://reactome.org/PathwayBrowser/#/R-RNO-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Rattus norvegicus 4053 R-RNO-2464822 https://reactome.org/PathwayBrowser/#/R-RNO-2464822 RDH12 reduces atRAL to atROL IEA Rattus norvegicus 4053 R-RNO-2465938 https://reactome.org/PathwayBrowser/#/R-RNO-2465938 RBP3 regulates atROL taken up by Muller cells IEA Rattus norvegicus 4053 R-RNO-2465940 https://reactome.org/PathwayBrowser/#/R-RNO-2465940 atRAL is reduced to atROL IEA Rattus norvegicus 4053 R-RNO-2465971 https://reactome.org/PathwayBrowser/#/R-RNO-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Rattus norvegicus 4053 R-RNO-2855252 https://reactome.org/PathwayBrowser/#/R-RNO-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 4053 R-RNO-2855259 https://reactome.org/PathwayBrowser/#/R-RNO-2855259 atROL binds RBP1 (parenchymal cell) IEA Rattus norvegicus 4053 R-RNO-5246478 https://reactome.org/PathwayBrowser/#/R-RNO-5246478 APOM binds retinoids IEA Rattus norvegicus 4053 R-RNO-5362518 https://reactome.org/PathwayBrowser/#/R-RNO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Rattus norvegicus 4053 R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 4053 R-RNO-5419165 https://reactome.org/PathwayBrowser/#/R-RNO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Rattus norvegicus 4053 R-RNO-5615668 https://reactome.org/PathwayBrowser/#/R-RNO-5615668 AKR1C3 reduces atRAL to atROL IEA Rattus norvegicus 4053 R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 4053 R-RNO-74843 https://reactome.org/PathwayBrowser/#/R-RNO-74843 atROL binds RBP1 to form RBP1:atROL IEA Rattus norvegicus 4053 R-RNO-8848355 https://reactome.org/PathwayBrowser/#/R-RNO-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Rattus norvegicus 4053 R-RNO-8848585 https://reactome.org/PathwayBrowser/#/R-RNO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Rattus norvegicus 4053 R-RNO-975593 https://reactome.org/PathwayBrowser/#/R-RNO-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Rattus norvegicus 4053 R-RNO-975594 https://reactome.org/PathwayBrowser/#/R-RNO-975594 PLB1 hydrolyses RPALM to atROL IEA Rattus norvegicus 4053 R-RNO-975608 https://reactome.org/PathwayBrowser/#/R-RNO-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Rattus norvegicus 4053 R-RNO-975629 https://reactome.org/PathwayBrowser/#/R-RNO-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 4053 R-RNO-975633 https://reactome.org/PathwayBrowser/#/R-RNO-975633 atROL binds to RBP2 IEA Rattus norvegicus 4053 R-SCE-2465940 https://reactome.org/PathwayBrowser/#/R-SCE-2465940 atRAL is reduced to atROL IEA Saccharomyces cerevisiae 4053 R-SCE-5362518 https://reactome.org/PathwayBrowser/#/R-SCE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Saccharomyces cerevisiae 4053 R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 4053 R-SCE-5419165 https://reactome.org/PathwayBrowser/#/R-SCE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Saccharomyces cerevisiae 4053 R-SCE-5615668 https://reactome.org/PathwayBrowser/#/R-SCE-5615668 AKR1C3 reduces atRAL to atROL IEA Saccharomyces cerevisiae 4053 R-SCE-8848585 https://reactome.org/PathwayBrowser/#/R-SCE-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Saccharomyces cerevisiae 4053 R-SPO-5362518 https://reactome.org/PathwayBrowser/#/R-SPO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Schizosaccharomyces pombe 4053 R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 4053 R-SPO-5419165 https://reactome.org/PathwayBrowser/#/R-SPO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Schizosaccharomyces pombe 4053 R-SPO-5615668 https://reactome.org/PathwayBrowser/#/R-SPO-5615668 AKR1C3 reduces atRAL to atROL IEA Schizosaccharomyces pombe 4053 R-SPO-8848585 https://reactome.org/PathwayBrowser/#/R-SPO-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Schizosaccharomyces pombe 4053 R-SSC-2404134 https://reactome.org/PathwayBrowser/#/R-SSC-2404134 RBP4:atROL binds TTR IEA Sus scrofa 4053 R-SSC-2404135 https://reactome.org/PathwayBrowser/#/R-SSC-2404135 RBP4 binds atROL IEA Sus scrofa 4053 R-SSC-2404137 https://reactome.org/PathwayBrowser/#/R-SSC-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 4053 R-SSC-2404142 https://reactome.org/PathwayBrowser/#/R-SSC-2404142 atROL binds RBP1 IEA Sus scrofa 4053 R-SSC-2404144 https://reactome.org/PathwayBrowser/#/R-SSC-2404144 Parenchymal atROL translocates to HSCs IEA Sus scrofa 4053 R-SSC-2453855 https://reactome.org/PathwayBrowser/#/R-SSC-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Sus scrofa 4053 R-SSC-2453863 https://reactome.org/PathwayBrowser/#/R-SSC-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Sus scrofa 4053 R-SSC-2453876 https://reactome.org/PathwayBrowser/#/R-SSC-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Sus scrofa 4053 R-SSC-2464809 https://reactome.org/PathwayBrowser/#/R-SSC-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Sus scrofa 4053 R-SSC-2464822 https://reactome.org/PathwayBrowser/#/R-SSC-2464822 RDH12 reduces atRAL to atROL IEA Sus scrofa 4053 R-SSC-2465938 https://reactome.org/PathwayBrowser/#/R-SSC-2465938 RBP3 regulates atROL taken up by Muller cells IEA Sus scrofa 4053 R-SSC-2465940 https://reactome.org/PathwayBrowser/#/R-SSC-2465940 atRAL is reduced to atROL IEA Sus scrofa 4053 R-SSC-2465971 https://reactome.org/PathwayBrowser/#/R-SSC-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Sus scrofa 4053 R-SSC-2855252 https://reactome.org/PathwayBrowser/#/R-SSC-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Sus scrofa 4053 R-SSC-2855259 https://reactome.org/PathwayBrowser/#/R-SSC-2855259 atROL binds RBP1 (parenchymal cell) IEA Sus scrofa 4053 R-SSC-5246478 https://reactome.org/PathwayBrowser/#/R-SSC-5246478 APOM binds retinoids IEA Sus scrofa 4053 R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa 4053 R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 4053 R-SSC-5419165 https://reactome.org/PathwayBrowser/#/R-SSC-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Sus scrofa 4053 R-SSC-5615668 https://reactome.org/PathwayBrowser/#/R-SSC-5615668 AKR1C3 reduces atRAL to atROL IEA Sus scrofa 4053 R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 4053 R-SSC-74843 https://reactome.org/PathwayBrowser/#/R-SSC-74843 atROL binds RBP1 to form RBP1:atROL IEA Sus scrofa 4053 R-SSC-8848355 https://reactome.org/PathwayBrowser/#/R-SSC-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Sus scrofa 4053 R-SSC-8848585 https://reactome.org/PathwayBrowser/#/R-SSC-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Sus scrofa 4053 R-SSC-975593 https://reactome.org/PathwayBrowser/#/R-SSC-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Sus scrofa 4053 R-SSC-975594 https://reactome.org/PathwayBrowser/#/R-SSC-975594 PLB1 hydrolyses RPALM to atROL IEA Sus scrofa 4053 R-SSC-975608 https://reactome.org/PathwayBrowser/#/R-SSC-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Sus scrofa 4053 R-SSC-975629 https://reactome.org/PathwayBrowser/#/R-SSC-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Sus scrofa 4053 R-SSC-975633 https://reactome.org/PathwayBrowser/#/R-SSC-975633 atROL binds to RBP2 IEA Sus scrofa 4053 R-XTR-2404134 https://reactome.org/PathwayBrowser/#/R-XTR-2404134 RBP4:atROL binds TTR IEA Xenopus tropicalis 4053 R-XTR-2404135 https://reactome.org/PathwayBrowser/#/R-XTR-2404135 RBP4 binds atROL IEA Xenopus tropicalis 4053 R-XTR-2404137 https://reactome.org/PathwayBrowser/#/R-XTR-2404137 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 4053 R-XTR-2404142 https://reactome.org/PathwayBrowser/#/R-XTR-2404142 atROL binds RBP1 IEA Xenopus tropicalis 4053 R-XTR-2404144 https://reactome.org/PathwayBrowser/#/R-XTR-2404144 Parenchymal atROL translocates to HSCs IEA Xenopus tropicalis 4053 R-XTR-2453855 https://reactome.org/PathwayBrowser/#/R-XTR-2453855 LRAT esterifies RBP1:atROL and FACYLs to atREs IEA Xenopus tropicalis 4053 R-XTR-2453863 https://reactome.org/PathwayBrowser/#/R-XTR-2453863 STRA6 transports atROL from extracellular region to cytosol IEA Xenopus tropicalis 4053 R-XTR-2453876 https://reactome.org/PathwayBrowser/#/R-XTR-2453876 TTR:RBP:atROL binds to STRA6 receptor IEA Xenopus tropicalis 4053 R-XTR-2464809 https://reactome.org/PathwayBrowser/#/R-XTR-2464809 RBP3 regulates the transport of atROL from ROS to RPE IEA Xenopus tropicalis 4053 R-XTR-2465938 https://reactome.org/PathwayBrowser/#/R-XTR-2465938 RBP3 regulates atROL taken up by Muller cells IEA Xenopus tropicalis 4053 R-XTR-2465940 https://reactome.org/PathwayBrowser/#/R-XTR-2465940 atRAL is reduced to atROL IEA Xenopus tropicalis 4053 R-XTR-2465971 https://reactome.org/PathwayBrowser/#/R-XTR-2465971 RLBP1 binds atROL to form RLBP1:atROL IEA Xenopus tropicalis 4053 R-XTR-2855252 https://reactome.org/PathwayBrowser/#/R-XTR-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Xenopus tropicalis 4053 R-XTR-2855259 https://reactome.org/PathwayBrowser/#/R-XTR-2855259 atROL binds RBP1 (parenchymal cell) IEA Xenopus tropicalis 4053 R-XTR-5246478 https://reactome.org/PathwayBrowser/#/R-XTR-5246478 APOM binds retinoids IEA Xenopus tropicalis 4053 R-XTR-5362518 https://reactome.org/PathwayBrowser/#/R-XTR-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Xenopus tropicalis 4053 R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 4053 R-XTR-5419165 https://reactome.org/PathwayBrowser/#/R-XTR-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Xenopus tropicalis 4053 R-XTR-5615668 https://reactome.org/PathwayBrowser/#/R-XTR-5615668 AKR1C3 reduces atRAL to atROL IEA Xenopus tropicalis 4053 R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 4053 R-XTR-74843 https://reactome.org/PathwayBrowser/#/R-XTR-74843 atROL binds RBP1 to form RBP1:atROL IEA Xenopus tropicalis 4053 R-XTR-8848355 https://reactome.org/PathwayBrowser/#/R-XTR-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Xenopus tropicalis 4053 R-XTR-8848585 https://reactome.org/PathwayBrowser/#/R-XTR-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM IEA Xenopus tropicalis 4053 R-XTR-975593 https://reactome.org/PathwayBrowser/#/R-XTR-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Xenopus tropicalis 4053 R-XTR-975608 https://reactome.org/PathwayBrowser/#/R-XTR-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs IEA Xenopus tropicalis 4053 R-XTR-975633 https://reactome.org/PathwayBrowser/#/R-XTR-975633 atROL binds to RBP2 IEA Xenopus tropicalis 407 R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 407 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 407 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 407 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 407 R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 407 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 407 R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 407 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 407 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 407 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 407 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 407 R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 407 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 407 R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 407 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 407 R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 407 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 407 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 407 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 407 R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 407 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 407 R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 407 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 407 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 407 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 407 R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 407 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 407 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 407 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 407 R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 407 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 407 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 407 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 407 R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 407 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 407 R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 407 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 407 R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 407 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 407 R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 407 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 407 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 407 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 407 R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 407 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 407 R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 407 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 407 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 407 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 4128 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 4139 R-BTA-2314678 https://reactome.org/PathwayBrowser/#/R-BTA-2314678 ASA- acetylates PTGS1 IEA Bos taurus 4139 R-BTA-2314686 https://reactome.org/PathwayBrowser/#/R-BTA-2314686 ASA- acetylates PTGS2 IEA Bos taurus 4139 R-BTA-9649963 https://reactome.org/PathwayBrowser/#/R-BTA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Bos taurus 4139 R-CEL-9649963 https://reactome.org/PathwayBrowser/#/R-CEL-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Caenorhabditis elegans 4139 R-CFA-2314678 https://reactome.org/PathwayBrowser/#/R-CFA-2314678 ASA- acetylates PTGS1 IEA Canis familiaris 4139 R-CFA-2314686 https://reactome.org/PathwayBrowser/#/R-CFA-2314686 ASA- acetylates PTGS2 IEA Canis familiaris 4139 R-CFA-9649963 https://reactome.org/PathwayBrowser/#/R-CFA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Canis familiaris 4139 R-DME-9649963 https://reactome.org/PathwayBrowser/#/R-DME-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Drosophila melanogaster 4139 R-DRE-2314678 https://reactome.org/PathwayBrowser/#/R-DRE-2314678 ASA- acetylates PTGS1 IEA Danio rerio 4139 R-DRE-2314686 https://reactome.org/PathwayBrowser/#/R-DRE-2314686 ASA- acetylates PTGS2 IEA Danio rerio 4139 R-DRE-9649963 https://reactome.org/PathwayBrowser/#/R-DRE-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Danio rerio 4139 R-GGA-2314678 https://reactome.org/PathwayBrowser/#/R-GGA-2314678 ASA- acetylates PTGS1 IEA Gallus gallus 4139 R-GGA-2314686 https://reactome.org/PathwayBrowser/#/R-GGA-2314686 ASA- acetylates PTGS2 IEA Gallus gallus 4139 R-GGA-9649963 https://reactome.org/PathwayBrowser/#/R-GGA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Gallus gallus 4139 R-HSA-2314678 https://reactome.org/PathwayBrowser/#/R-HSA-2314678 ASA- acetylates PTGS1 TAS Homo sapiens 4139 R-HSA-2314686 https://reactome.org/PathwayBrowser/#/R-HSA-2314686 ASA- acetylates PTGS2 TAS Homo sapiens 4139 R-HSA-9649963 https://reactome.org/PathwayBrowser/#/R-HSA-9649963 ASIC3 channel blockers bind ASIC3 trimer TAS Homo sapiens 4139 R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 4139 R-MMU-2314678 https://reactome.org/PathwayBrowser/#/R-MMU-2314678 ASA- acetylates PTGS1 IEA Mus musculus 4139 R-MMU-2314686 https://reactome.org/PathwayBrowser/#/R-MMU-2314686 ASA- acetylates PTGS2 IEA Mus musculus 4139 R-MMU-9649963 https://reactome.org/PathwayBrowser/#/R-MMU-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Mus musculus 4139 R-RNO-2314678 https://reactome.org/PathwayBrowser/#/R-RNO-2314678 ASA- acetylates PTGS1 IEA Rattus norvegicus 4139 R-RNO-2314686 https://reactome.org/PathwayBrowser/#/R-RNO-2314686 ASA- acetylates PTGS2 IEA Rattus norvegicus 4139 R-RNO-9649963 https://reactome.org/PathwayBrowser/#/R-RNO-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Rattus norvegicus 4139 R-SSC-2314678 https://reactome.org/PathwayBrowser/#/R-SSC-2314678 ASA- acetylates PTGS1 IEA Sus scrofa 4139 R-SSC-2314686 https://reactome.org/PathwayBrowser/#/R-SSC-2314686 ASA- acetylates PTGS2 IEA Sus scrofa 4139 R-SSC-9649963 https://reactome.org/PathwayBrowser/#/R-SSC-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Sus scrofa 4139 R-XTR-2314678 https://reactome.org/PathwayBrowser/#/R-XTR-2314678 ASA- acetylates PTGS1 IEA Xenopus tropicalis 4139 R-XTR-2314686 https://reactome.org/PathwayBrowser/#/R-XTR-2314686 ASA- acetylates PTGS2 IEA Xenopus tropicalis 4139 R-XTR-9649963 https://reactome.org/PathwayBrowser/#/R-XTR-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Xenopus tropicalis 4159 R-BTA-9716913 https://reactome.org/PathwayBrowser/#/R-BTA-9716913 ESR1 binds ESR1 antagonists IEA Bos taurus 4159 R-DME-9716913 https://reactome.org/PathwayBrowser/#/R-DME-9716913 ESR1 binds ESR1 antagonists IEA Drosophila melanogaster 4159 R-DRE-9716913 https://reactome.org/PathwayBrowser/#/R-DRE-9716913 ESR1 binds ESR1 antagonists IEA Danio rerio 4159 R-GGA-9716913 https://reactome.org/PathwayBrowser/#/R-GGA-9716913 ESR1 binds ESR1 antagonists IEA Gallus gallus 4159 R-HSA-9716913 https://reactome.org/PathwayBrowser/#/R-HSA-9716913 ESR1 binds ESR1 antagonists TAS Homo sapiens 4159 R-MMU-9716913 https://reactome.org/PathwayBrowser/#/R-MMU-9716913 ESR1 binds ESR1 antagonists IEA Mus musculus 4159 R-RNO-9716913 https://reactome.org/PathwayBrowser/#/R-RNO-9716913 ESR1 binds ESR1 antagonists IEA Rattus norvegicus 4159 R-SSC-9716913 https://reactome.org/PathwayBrowser/#/R-SSC-9716913 ESR1 binds ESR1 antagonists IEA Sus scrofa 4159 R-XTR-9716913 https://reactome.org/PathwayBrowser/#/R-XTR-9716913 ESR1 binds ESR1 antagonists IEA Xenopus tropicalis 4190 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 4190 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 4190 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 4190 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 4190 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 4190 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 4190 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 4190 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 4190 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 4190 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 4190 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 4190 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 4190 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 4190 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 4190 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 4194 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 4194 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 4194 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 4194 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 4194 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 4194 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 4194 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 4194 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 4194 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 4194 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 4194 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 4194 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 4194 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 4194 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 4194 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 4194 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 4194 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 4194 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 4214 R-BTA-140791 https://reactome.org/PathwayBrowser/#/R-BTA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Bos taurus 4214 R-BTA-140806 https://reactome.org/PathwayBrowser/#/R-BTA-140806 SERPINC1 binds SERPINC1 activators IEA Bos taurus 4214 R-BTA-140870 https://reactome.org/PathwayBrowser/#/R-BTA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Bos taurus 4214 R-BTA-140872 https://reactome.org/PathwayBrowser/#/R-BTA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Bos taurus 4214 R-BTA-9835121 https://reactome.org/PathwayBrowser/#/R-BTA-9835121 Heparin binds PKR IEA Bos taurus 4214 R-CEL-140806 https://reactome.org/PathwayBrowser/#/R-CEL-140806 SERPINC1 binds SERPINC1 activators IEA Caenorhabditis elegans 4214 R-CEL-9835121 https://reactome.org/PathwayBrowser/#/R-CEL-9835121 Heparin binds PKR IEA Caenorhabditis elegans 4214 R-CFA-140791 https://reactome.org/PathwayBrowser/#/R-CFA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Canis familiaris 4214 R-CFA-140806 https://reactome.org/PathwayBrowser/#/R-CFA-140806 SERPINC1 binds SERPINC1 activators IEA Canis familiaris 4214 R-CFA-140870 https://reactome.org/PathwayBrowser/#/R-CFA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Canis familiaris 4214 R-CFA-140872 https://reactome.org/PathwayBrowser/#/R-CFA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Canis familiaris 4214 R-CFA-9835121 https://reactome.org/PathwayBrowser/#/R-CFA-9835121 Heparin binds PKR IEA Canis familiaris 4214 R-DME-140806 https://reactome.org/PathwayBrowser/#/R-DME-140806 SERPINC1 binds SERPINC1 activators IEA Drosophila melanogaster 4214 R-DME-9835121 https://reactome.org/PathwayBrowser/#/R-DME-9835121 Heparin binds PKR IEA Drosophila melanogaster 4214 R-DRE-140806 https://reactome.org/PathwayBrowser/#/R-DRE-140806 SERPINC1 binds SERPINC1 activators IEA Danio rerio 4214 R-DRE-9835121 https://reactome.org/PathwayBrowser/#/R-DRE-9835121 Heparin binds PKR IEA Danio rerio 4214 R-GGA-140791 https://reactome.org/PathwayBrowser/#/R-GGA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Gallus gallus 4214 R-GGA-140806 https://reactome.org/PathwayBrowser/#/R-GGA-140806 SERPINC1 binds SERPINC1 activators IEA Gallus gallus 4214 R-GGA-140870 https://reactome.org/PathwayBrowser/#/R-GGA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Gallus gallus 4214 R-GGA-140872 https://reactome.org/PathwayBrowser/#/R-GGA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Gallus gallus 4214 R-GGA-9835121 https://reactome.org/PathwayBrowser/#/R-GGA-9835121 Heparin binds PKR IEA Gallus gallus 4214 R-HSA-140791 https://reactome.org/PathwayBrowser/#/R-HSA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin TAS Homo sapiens 4214 R-HSA-140806 https://reactome.org/PathwayBrowser/#/R-HSA-140806 SERPINC1 binds SERPINC1 activators TAS Homo sapiens 4214 R-HSA-140870 https://reactome.org/PathwayBrowser/#/R-HSA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin TAS Homo sapiens 4214 R-HSA-140872 https://reactome.org/PathwayBrowser/#/R-HSA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators TAS Homo sapiens 4214 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 4214 R-HSA-9699007 https://reactome.org/PathwayBrowser/#/R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 4214 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 4214 R-HSA-9769949 https://reactome.org/PathwayBrowser/#/R-HSA-9769949 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage TAS Homo sapiens 4214 R-HSA-9833723 https://reactome.org/PathwayBrowser/#/R-HSA-9833723 PKR forms a dimer TAS Homo sapiens 4214 R-HSA-9835121 https://reactome.org/PathwayBrowser/#/R-HSA-9835121 Heparin binds PKR TAS Homo sapiens 4214 R-MMU-140791 https://reactome.org/PathwayBrowser/#/R-MMU-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Mus musculus 4214 R-MMU-140806 https://reactome.org/PathwayBrowser/#/R-MMU-140806 SERPINC1 binds SERPINC1 activators IEA Mus musculus 4214 R-MMU-140870 https://reactome.org/PathwayBrowser/#/R-MMU-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Mus musculus 4214 R-MMU-140872 https://reactome.org/PathwayBrowser/#/R-MMU-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Mus musculus 4214 R-MMU-9835121 https://reactome.org/PathwayBrowser/#/R-MMU-9835121 Heparin binds PKR IEA Mus musculus 4214 R-RNO-140791 https://reactome.org/PathwayBrowser/#/R-RNO-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Rattus norvegicus 4214 R-RNO-140806 https://reactome.org/PathwayBrowser/#/R-RNO-140806 SERPINC1 binds SERPINC1 activators IEA Rattus norvegicus 4214 R-RNO-140870 https://reactome.org/PathwayBrowser/#/R-RNO-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Rattus norvegicus 4214 R-RNO-140872 https://reactome.org/PathwayBrowser/#/R-RNO-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Rattus norvegicus 4214 R-RNO-9835121 https://reactome.org/PathwayBrowser/#/R-RNO-9835121 Heparin binds PKR IEA Rattus norvegicus 4214 R-SSC-140791 https://reactome.org/PathwayBrowser/#/R-SSC-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Sus scrofa 4214 R-SSC-140806 https://reactome.org/PathwayBrowser/#/R-SSC-140806 SERPINC1 binds SERPINC1 activators IEA Sus scrofa 4214 R-SSC-140870 https://reactome.org/PathwayBrowser/#/R-SSC-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Sus scrofa 4214 R-SSC-140872 https://reactome.org/PathwayBrowser/#/R-SSC-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Sus scrofa 4214 R-SSC-9835121 https://reactome.org/PathwayBrowser/#/R-SSC-9835121 Heparin binds PKR IEA Sus scrofa 4214 R-XTR-140791 https://reactome.org/PathwayBrowser/#/R-XTR-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Xenopus tropicalis 4214 R-XTR-140806 https://reactome.org/PathwayBrowser/#/R-XTR-140806 SERPINC1 binds SERPINC1 activators IEA Xenopus tropicalis 4214 R-XTR-140870 https://reactome.org/PathwayBrowser/#/R-XTR-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Xenopus tropicalis 4214 R-XTR-140872 https://reactome.org/PathwayBrowser/#/R-XTR-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Xenopus tropicalis 4214 R-XTR-9835121 https://reactome.org/PathwayBrowser/#/R-XTR-9835121 Heparin binds PKR IEA Xenopus tropicalis 4252 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 4252 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 4252 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 4252 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 4252 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 4252 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 4252 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 4252 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 4252 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 4262 R-BTA-9649963 https://reactome.org/PathwayBrowser/#/R-BTA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Bos taurus 4262 R-CEL-9649963 https://reactome.org/PathwayBrowser/#/R-CEL-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Caenorhabditis elegans 4262 R-CFA-9649963 https://reactome.org/PathwayBrowser/#/R-CFA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Canis familiaris 4262 R-DME-9649963 https://reactome.org/PathwayBrowser/#/R-DME-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Drosophila melanogaster 4262 R-DRE-9649963 https://reactome.org/PathwayBrowser/#/R-DRE-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Danio rerio 4262 R-GGA-9649963 https://reactome.org/PathwayBrowser/#/R-GGA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Gallus gallus 4262 R-HSA-9649963 https://reactome.org/PathwayBrowser/#/R-HSA-9649963 ASIC3 channel blockers bind ASIC3 trimer TAS Homo sapiens 4262 R-HSA-9681514 https://reactome.org/PathwayBrowser/#/R-HSA-9681514 TMPRSS2 binds TMPRSS2 inhibitors TAS Homo sapiens 4262 R-HSA-9686731 https://reactome.org/PathwayBrowser/#/R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 4262 R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 4262 R-MMU-9649963 https://reactome.org/PathwayBrowser/#/R-MMU-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Mus musculus 4262 R-RNO-9649963 https://reactome.org/PathwayBrowser/#/R-RNO-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Rattus norvegicus 4262 R-SSC-9649963 https://reactome.org/PathwayBrowser/#/R-SSC-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Sus scrofa 4262 R-XTR-9649963 https://reactome.org/PathwayBrowser/#/R-XTR-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Xenopus tropicalis 4279 R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 4279 R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 4279 R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 4279 R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 4279 R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 4279 R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 4279 R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 4279 R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 4279 R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 4279 R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 4279 R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 4279 R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 4279 R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 4279 R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 4279 R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 4279 R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 4290 R-BTA-176517 https://reactome.org/PathwayBrowser/#/R-BTA-176517 SULTs transfer (SO4)2- group to PREG IEA Bos taurus 4290 R-CFA-176517 https://reactome.org/PathwayBrowser/#/R-CFA-176517 SULTs transfer (SO4)2- group to PREG IEA Canis familiaris 4290 R-DME-176517 https://reactome.org/PathwayBrowser/#/R-DME-176517 SULTs transfer (SO4)2- group to PREG IEA Drosophila melanogaster 4290 R-DRE-176517 https://reactome.org/PathwayBrowser/#/R-DRE-176517 SULTs transfer (SO4)2- group to PREG IEA Danio rerio 4290 R-GGA-176517 https://reactome.org/PathwayBrowser/#/R-GGA-176517 SULTs transfer (SO4)2- group to PREG IEA Gallus gallus 4290 R-HSA-176517 https://reactome.org/PathwayBrowser/#/R-HSA-176517 SULTs transfer (SO4)2- group to PREG TAS Homo sapiens 4290 R-MMU-176517 https://reactome.org/PathwayBrowser/#/R-MMU-176517 SULTs transfer (SO4)2- group to PREG IEA Mus musculus 4290 R-RNO-176517 https://reactome.org/PathwayBrowser/#/R-RNO-176517 SULTs transfer (SO4)2- group to PREG IEA Rattus norvegicus 4290 R-SSC-176517 https://reactome.org/PathwayBrowser/#/R-SSC-176517 SULTs transfer (SO4)2- group to PREG IEA Sus scrofa 4290 R-XTR-176517 https://reactome.org/PathwayBrowser/#/R-XTR-176517 SULTs transfer (SO4)2- group to PREG IEA Xenopus tropicalis 43 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 43 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 43 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 43 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 43 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 43 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 43 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 43 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 43 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 43 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 4342 R-HSA-5678992 https://reactome.org/PathwayBrowser/#/R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region TAS Homo sapiens 4342 R-HSA-5679000 https://reactome.org/PathwayBrowser/#/R-HSA-5679000 Ivacaftor binds CFTR G551D TAS Homo sapiens 4350 R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 4350 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 4350 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 4350 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 4350 R-BTA-8851679 https://reactome.org/PathwayBrowser/#/R-BTA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Bos taurus 4350 R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 4350 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 4350 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 4350 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 4350 R-CFA-8851679 https://reactome.org/PathwayBrowser/#/R-CFA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Canis familiaris 4350 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 4350 R-DRE-8851679 https://reactome.org/PathwayBrowser/#/R-DRE-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Danio rerio 4350 R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 4350 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 4350 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 4350 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 4350 R-GGA-8851679 https://reactome.org/PathwayBrowser/#/R-GGA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Gallus gallus 4350 R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 4350 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 4350 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 4350 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 4350 R-HSA-8851679 https://reactome.org/PathwayBrowser/#/R-HSA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol TAS Homo sapiens 4350 R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 4350 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 4350 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 4350 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 4350 R-MMU-8851679 https://reactome.org/PathwayBrowser/#/R-MMU-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Mus musculus 4350 R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 4350 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 4350 R-RNO-8851679 https://reactome.org/PathwayBrowser/#/R-RNO-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Rattus norvegicus 4350 R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 4350 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 4350 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 4350 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 4350 R-SSC-8851679 https://reactome.org/PathwayBrowser/#/R-SSC-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Sus scrofa 4350 R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 4350 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 4350 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 4350 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 4350 R-XTR-8851679 https://reactome.org/PathwayBrowser/#/R-XTR-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol IEA Xenopus tropicalis 4351 R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 4351 R-BTA-192097 https://reactome.org/PathwayBrowser/#/R-BTA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Bos taurus 4351 R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 4351 R-CFA-192097 https://reactome.org/PathwayBrowser/#/R-CFA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Canis familiaris 4351 R-DRE-192097 https://reactome.org/PathwayBrowser/#/R-DRE-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Danio rerio 4351 R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 4351 R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 4351 R-HSA-192097 https://reactome.org/PathwayBrowser/#/R-HSA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one TAS Homo sapiens 4351 R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 4351 R-MMU-192097 https://reactome.org/PathwayBrowser/#/R-MMU-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Mus musculus 4351 R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 4351 R-RNO-192097 https://reactome.org/PathwayBrowser/#/R-RNO-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Rattus norvegicus 4351 R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 4351 R-SSC-192097 https://reactome.org/PathwayBrowser/#/R-SSC-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Sus scrofa 4351 R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 4351 R-XTR-192097 https://reactome.org/PathwayBrowser/#/R-XTR-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Xenopus tropicalis 4353 R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 4353 R-BTA-193816 https://reactome.org/PathwayBrowser/#/R-BTA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Bos taurus 4353 R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 4353 R-CFA-193816 https://reactome.org/PathwayBrowser/#/R-CFA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Canis familiaris 4353 R-DRE-193816 https://reactome.org/PathwayBrowser/#/R-DRE-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Danio rerio 4353 R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 4353 R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 4353 R-HSA-193816 https://reactome.org/PathwayBrowser/#/R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one TAS Homo sapiens 4353 R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 4353 R-MMU-193816 https://reactome.org/PathwayBrowser/#/R-MMU-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Mus musculus 4353 R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 4353 R-RNO-193816 https://reactome.org/PathwayBrowser/#/R-RNO-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Rattus norvegicus 4353 R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 4353 R-SSC-193816 https://reactome.org/PathwayBrowser/#/R-SSC-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Sus scrofa 4353 R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 4353 R-XTR-193816 https://reactome.org/PathwayBrowser/#/R-XTR-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Xenopus tropicalis 4488 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 4488 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 4488 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 4488 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 4488 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 4488 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 4488 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 4488 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 4488 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 4488 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 4495 R-BTA-1482976 https://reactome.org/PathwayBrowser/#/R-BTA-1482976 CDP-DAG is converted to PI by CDIPT IEA Bos taurus 4495 R-BTA-1855154 https://reactome.org/PathwayBrowser/#/R-BTA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 4495 R-BTA-1855210 https://reactome.org/PathwayBrowser/#/R-BTA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 4495 R-BTA-1855211 https://reactome.org/PathwayBrowser/#/R-BTA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 4495 R-BTA-429101 https://reactome.org/PathwayBrowser/#/R-BTA-429101 HMIT co-transports myo-inositol with a proton IEA Bos taurus 4495 R-BTA-429571 https://reactome.org/PathwayBrowser/#/R-BTA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Bos taurus 4495 R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 4495 R-BTA-6813740 https://reactome.org/PathwayBrowser/#/R-BTA-6813740 GDE1 hydrolyzes GroPIns IEA Bos taurus 4495 R-CEL-1482976 https://reactome.org/PathwayBrowser/#/R-CEL-1482976 CDP-DAG is converted to PI by CDIPT IEA Caenorhabditis elegans 4495 R-CEL-1855154 https://reactome.org/PathwayBrowser/#/R-CEL-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 4495 R-CEL-1855210 https://reactome.org/PathwayBrowser/#/R-CEL-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 4495 R-CEL-1855211 https://reactome.org/PathwayBrowser/#/R-CEL-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 4495 R-CEL-429101 https://reactome.org/PathwayBrowser/#/R-CEL-429101 HMIT co-transports myo-inositol with a proton IEA Caenorhabditis elegans 4495 R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 4495 R-CEL-6813740 https://reactome.org/PathwayBrowser/#/R-CEL-6813740 GDE1 hydrolyzes GroPIns IEA Caenorhabditis elegans 4495 R-CFA-1482976 https://reactome.org/PathwayBrowser/#/R-CFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Canis familiaris 4495 R-CFA-1855154 https://reactome.org/PathwayBrowser/#/R-CFA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 4495 R-CFA-1855210 https://reactome.org/PathwayBrowser/#/R-CFA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 4495 R-CFA-1855211 https://reactome.org/PathwayBrowser/#/R-CFA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 4495 R-CFA-429101 https://reactome.org/PathwayBrowser/#/R-CFA-429101 HMIT co-transports myo-inositol with a proton IEA Canis familiaris 4495 R-CFA-429571 https://reactome.org/PathwayBrowser/#/R-CFA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Canis familiaris 4495 R-CFA-429663 https://reactome.org/PathwayBrowser/#/R-CFA-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Canis familiaris 4495 R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 4495 R-CFA-6813740 https://reactome.org/PathwayBrowser/#/R-CFA-6813740 GDE1 hydrolyzes GroPIns IEA Canis familiaris 4495 R-DDI-1482976 https://reactome.org/PathwayBrowser/#/R-DDI-1482976 CDP-DAG is converted to PI by CDIPT IEA Dictyostelium discoideum 4495 R-DDI-1855154 https://reactome.org/PathwayBrowser/#/R-DDI-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 4495 R-DDI-1855210 https://reactome.org/PathwayBrowser/#/R-DDI-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 4495 R-DDI-1855211 https://reactome.org/PathwayBrowser/#/R-DDI-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 4495 R-DDI-429101 https://reactome.org/PathwayBrowser/#/R-DDI-429101 HMIT co-transports myo-inositol with a proton IEA Dictyostelium discoideum 4495 R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 4495 R-DME-1482976 https://reactome.org/PathwayBrowser/#/R-DME-1482976 CDP-DAG is converted to PI by CDIPT IEA Drosophila melanogaster 4495 R-DME-1855154 https://reactome.org/PathwayBrowser/#/R-DME-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 4495 R-DME-1855210 https://reactome.org/PathwayBrowser/#/R-DME-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 4495 R-DME-1855211 https://reactome.org/PathwayBrowser/#/R-DME-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 4495 R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 4495 R-DME-6813740 https://reactome.org/PathwayBrowser/#/R-DME-6813740 GDE1 hydrolyzes GroPIns IEA Drosophila melanogaster 4495 R-DRE-1482976 https://reactome.org/PathwayBrowser/#/R-DRE-1482976 CDP-DAG is converted to PI by CDIPT IEA Danio rerio 4495 R-DRE-1855154 https://reactome.org/PathwayBrowser/#/R-DRE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 4495 R-DRE-1855210 https://reactome.org/PathwayBrowser/#/R-DRE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 4495 R-DRE-1855211 https://reactome.org/PathwayBrowser/#/R-DRE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 4495 R-DRE-429571 https://reactome.org/PathwayBrowser/#/R-DRE-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Danio rerio 4495 R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 4495 R-DRE-6813740 https://reactome.org/PathwayBrowser/#/R-DRE-6813740 GDE1 hydrolyzes GroPIns IEA Danio rerio 4495 R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 4495 R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 4495 R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 4495 R-GGA-429101 https://reactome.org/PathwayBrowser/#/R-GGA-429101 HMIT co-transports myo-inositol with a proton IEA Gallus gallus 4495 R-GGA-429571 https://reactome.org/PathwayBrowser/#/R-GGA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Gallus gallus 4495 R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 4495 R-GGA-6813740 https://reactome.org/PathwayBrowser/#/R-GGA-6813740 GDE1 hydrolyzes GroPIns IEA Gallus gallus 4495 R-HSA-1482976 https://reactome.org/PathwayBrowser/#/R-HSA-1482976 CDP-DAG is converted to PI by CDIPT TAS Homo sapiens 4495 R-HSA-1855154 https://reactome.org/PathwayBrowser/#/R-HSA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 4495 R-HSA-1855210 https://reactome.org/PathwayBrowser/#/R-HSA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 4495 R-HSA-1855211 https://reactome.org/PathwayBrowser/#/R-HSA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 4495 R-HSA-429101 https://reactome.org/PathwayBrowser/#/R-HSA-429101 HMIT co-transports myo-inositol with a proton TAS Homo sapiens 4495 R-HSA-429571 https://reactome.org/PathwayBrowser/#/R-HSA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 TAS Homo sapiens 4495 R-HSA-429663 https://reactome.org/PathwayBrowser/#/R-HSA-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol TAS Homo sapiens 4495 R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 4495 R-HSA-6813740 https://reactome.org/PathwayBrowser/#/R-HSA-6813740 GDE1 hydrolyzes GroPIns TAS Homo sapiens 4495 R-MMU-1482976 https://reactome.org/PathwayBrowser/#/R-MMU-1482976 CDP-DAG is converted to PI by CDIPT IEA Mus musculus 4495 R-MMU-1855154 https://reactome.org/PathwayBrowser/#/R-MMU-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 4495 R-MMU-1855210 https://reactome.org/PathwayBrowser/#/R-MMU-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 4495 R-MMU-1855211 https://reactome.org/PathwayBrowser/#/R-MMU-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 4495 R-MMU-429101 https://reactome.org/PathwayBrowser/#/R-MMU-429101 HMIT co-transports myo-inositol with a proton IEA Mus musculus 4495 R-MMU-429571 https://reactome.org/PathwayBrowser/#/R-MMU-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Mus musculus 4495 R-MMU-429663 https://reactome.org/PathwayBrowser/#/R-MMU-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Mus musculus 4495 R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 4495 R-MMU-6813740 https://reactome.org/PathwayBrowser/#/R-MMU-6813740 GDE1 hydrolyzes GroPIns IEA Mus musculus 4495 R-PFA-1482976 https://reactome.org/PathwayBrowser/#/R-PFA-1482976 CDP-DAG is converted to PI by CDIPT IEA Plasmodium falciparum 4495 R-RNO-1482976 https://reactome.org/PathwayBrowser/#/R-RNO-1482976 CDP-DAG is converted to PI by CDIPT IEA Rattus norvegicus 4495 R-RNO-1855154 https://reactome.org/PathwayBrowser/#/R-RNO-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 4495 R-RNO-1855210 https://reactome.org/PathwayBrowser/#/R-RNO-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 4495 R-RNO-1855211 https://reactome.org/PathwayBrowser/#/R-RNO-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 4495 R-RNO-429101 https://reactome.org/PathwayBrowser/#/R-RNO-429101 HMIT co-transports myo-inositol with a proton IEA Rattus norvegicus 4495 R-RNO-429571 https://reactome.org/PathwayBrowser/#/R-RNO-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Rattus norvegicus 4495 R-RNO-429663 https://reactome.org/PathwayBrowser/#/R-RNO-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Rattus norvegicus 4495 R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 4495 R-RNO-6813740 https://reactome.org/PathwayBrowser/#/R-RNO-6813740 GDE1 hydrolyzes GroPIns IEA Rattus norvegicus 4495 R-SCE-1482976 https://reactome.org/PathwayBrowser/#/R-SCE-1482976 CDP-DAG is converted to PI by CDIPT IEA Saccharomyces cerevisiae 4495 R-SCE-1855154 https://reactome.org/PathwayBrowser/#/R-SCE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 4495 R-SCE-1855210 https://reactome.org/PathwayBrowser/#/R-SCE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 4495 R-SCE-1855211 https://reactome.org/PathwayBrowser/#/R-SCE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 4495 R-SCE-429101 https://reactome.org/PathwayBrowser/#/R-SCE-429101 HMIT co-transports myo-inositol with a proton IEA Saccharomyces cerevisiae 4495 R-SPO-1482976 https://reactome.org/PathwayBrowser/#/R-SPO-1482976 CDP-DAG is converted to PI by CDIPT IEA Schizosaccharomyces pombe 4495 R-SPO-429101 https://reactome.org/PathwayBrowser/#/R-SPO-429101 HMIT co-transports myo-inositol with a proton IEA Schizosaccharomyces pombe 4495 R-SSC-1482976 https://reactome.org/PathwayBrowser/#/R-SSC-1482976 CDP-DAG is converted to PI by CDIPT IEA Sus scrofa 4495 R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 4495 R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 4495 R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 4495 R-SSC-429101 https://reactome.org/PathwayBrowser/#/R-SSC-429101 HMIT co-transports myo-inositol with a proton IEA Sus scrofa 4495 R-SSC-429571 https://reactome.org/PathwayBrowser/#/R-SSC-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Sus scrofa 4495 R-SSC-429663 https://reactome.org/PathwayBrowser/#/R-SSC-429663 SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol IEA Sus scrofa 4495 R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 4495 R-SSC-6813740 https://reactome.org/PathwayBrowser/#/R-SSC-6813740 GDE1 hydrolyzes GroPIns IEA Sus scrofa 4495 R-XTR-1482976 https://reactome.org/PathwayBrowser/#/R-XTR-1482976 CDP-DAG is converted to PI by CDIPT IEA Xenopus tropicalis 4495 R-XTR-1855154 https://reactome.org/PathwayBrowser/#/R-XTR-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 4495 R-XTR-1855210 https://reactome.org/PathwayBrowser/#/R-XTR-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 4495 R-XTR-1855211 https://reactome.org/PathwayBrowser/#/R-XTR-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 4495 R-XTR-429101 https://reactome.org/PathwayBrowser/#/R-XTR-429101 HMIT co-transports myo-inositol with a proton IEA Xenopus tropicalis 4495 R-XTR-429571 https://reactome.org/PathwayBrowser/#/R-XTR-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Xenopus tropicalis 4495 R-XTR-6813740 https://reactome.org/PathwayBrowser/#/R-XTR-6813740 GDE1 hydrolyzes GroPIns IEA Xenopus tropicalis 45 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 45 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 45 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 45 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 45 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 45 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 45 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 45 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 45 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 45 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 4518 R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 4518 R-BTA-9011543 https://reactome.org/PathwayBrowser/#/R-BTA-9011543 DCA binds PDK2 IEA Bos taurus 4518 R-BTA-9011595 https://reactome.org/PathwayBrowser/#/R-BTA-9011595 GSTZ1 dimer dehalogenates DCA IEA Bos taurus 4518 R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 4518 R-CEL-9011543 https://reactome.org/PathwayBrowser/#/R-CEL-9011543 DCA binds PDK2 IEA Caenorhabditis elegans 4518 R-CEL-9011595 https://reactome.org/PathwayBrowser/#/R-CEL-9011595 GSTZ1 dimer dehalogenates DCA IEA Caenorhabditis elegans 4518 R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 4518 R-CFA-9011543 https://reactome.org/PathwayBrowser/#/R-CFA-9011543 DCA binds PDK2 IEA Canis familiaris 4518 R-CFA-9011595 https://reactome.org/PathwayBrowser/#/R-CFA-9011595 GSTZ1 dimer dehalogenates DCA IEA Canis familiaris 4518 R-DDI-9011595 https://reactome.org/PathwayBrowser/#/R-DDI-9011595 GSTZ1 dimer dehalogenates DCA IEA Dictyostelium discoideum 4518 R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 4518 R-DME-9011543 https://reactome.org/PathwayBrowser/#/R-DME-9011543 DCA binds PDK2 IEA Drosophila melanogaster 4518 R-DME-9011595 https://reactome.org/PathwayBrowser/#/R-DME-9011595 GSTZ1 dimer dehalogenates DCA IEA Drosophila melanogaster 4518 R-DRE-9011543 https://reactome.org/PathwayBrowser/#/R-DRE-9011543 DCA binds PDK2 IEA Danio rerio 4518 R-DRE-9011595 https://reactome.org/PathwayBrowser/#/R-DRE-9011595 GSTZ1 dimer dehalogenates DCA IEA Danio rerio 4518 R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 4518 R-GGA-9011543 https://reactome.org/PathwayBrowser/#/R-GGA-9011543 DCA binds PDK2 IEA Gallus gallus 4518 R-GGA-9011595 https://reactome.org/PathwayBrowser/#/R-GGA-9011595 GSTZ1 dimer dehalogenates DCA IEA Gallus gallus 4518 R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 4518 R-HSA-9011543 https://reactome.org/PathwayBrowser/#/R-HSA-9011543 DCA binds PDK2 TAS Homo sapiens 4518 R-HSA-9011595 https://reactome.org/PathwayBrowser/#/R-HSA-9011595 GSTZ1 dimer dehalogenates DCA TAS Homo sapiens 4518 R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 4518 R-MMU-9011543 https://reactome.org/PathwayBrowser/#/R-MMU-9011543 DCA binds PDK2 IEA Mus musculus 4518 R-MMU-9011595 https://reactome.org/PathwayBrowser/#/R-MMU-9011595 GSTZ1 dimer dehalogenates DCA IEA Mus musculus 4518 R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 4518 R-RNO-9011543 https://reactome.org/PathwayBrowser/#/R-RNO-9011543 DCA binds PDK2 IEA Rattus norvegicus 4518 R-RNO-9011595 https://reactome.org/PathwayBrowser/#/R-RNO-9011595 GSTZ1 dimer dehalogenates DCA IEA Rattus norvegicus 4518 R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 4518 R-SPO-9011543 https://reactome.org/PathwayBrowser/#/R-SPO-9011543 DCA binds PDK2 IEA Schizosaccharomyces pombe 4518 R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 4518 R-SSC-9011543 https://reactome.org/PathwayBrowser/#/R-SSC-9011543 DCA binds PDK2 IEA Sus scrofa 4518 R-SSC-9011595 https://reactome.org/PathwayBrowser/#/R-SSC-9011595 GSTZ1 dimer dehalogenates DCA IEA Sus scrofa 4518 R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 4518 R-XTR-9011543 https://reactome.org/PathwayBrowser/#/R-XTR-9011543 DCA binds PDK2 IEA Xenopus tropicalis 4518 R-XTR-9011595 https://reactome.org/PathwayBrowser/#/R-XTR-9011595 GSTZ1 dimer dehalogenates DCA IEA Xenopus tropicalis 4520 R-BTA-390291 https://reactome.org/PathwayBrowser/#/R-BTA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Bos taurus 4520 R-CEL-390291 https://reactome.org/PathwayBrowser/#/R-CEL-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Caenorhabditis elegans 4520 R-CFA-390291 https://reactome.org/PathwayBrowser/#/R-CFA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Canis familiaris 4520 R-DME-390291 https://reactome.org/PathwayBrowser/#/R-DME-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Drosophila melanogaster 4520 R-DRE-390291 https://reactome.org/PathwayBrowser/#/R-DRE-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Danio rerio 4520 R-GGA-390291 https://reactome.org/PathwayBrowser/#/R-GGA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Gallus gallus 4520 R-HSA-390291 https://reactome.org/PathwayBrowser/#/R-HSA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH TAS Homo sapiens 4520 R-MMU-390291 https://reactome.org/PathwayBrowser/#/R-MMU-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Mus musculus 4520 R-RNO-390291 https://reactome.org/PathwayBrowser/#/R-RNO-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Rattus norvegicus 4520 R-SSC-390291 https://reactome.org/PathwayBrowser/#/R-SSC-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Sus scrofa 4520 R-XTR-390291 https://reactome.org/PathwayBrowser/#/R-XTR-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Xenopus tropicalis 4522 R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 4522 R-BTA-73912 https://reactome.org/PathwayBrowser/#/R-BTA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Bos taurus 4522 R-BTA-73920 https://reactome.org/PathwayBrowser/#/R-BTA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Bos taurus 4522 R-BTA-74177 https://reactome.org/PathwayBrowser/#/R-BTA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Bos taurus 4522 R-BTA-74180 https://reactome.org/PathwayBrowser/#/R-BTA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Bos taurus 4522 R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 4522 R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 4522 R-CEL-74177 https://reactome.org/PathwayBrowser/#/R-CEL-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Caenorhabditis elegans 4522 R-CEL-74180 https://reactome.org/PathwayBrowser/#/R-CEL-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Caenorhabditis elegans 4522 R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 4522 R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 4522 R-CFA-73912 https://reactome.org/PathwayBrowser/#/R-CFA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Canis familiaris 4522 R-CFA-73920 https://reactome.org/PathwayBrowser/#/R-CFA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Canis familiaris 4522 R-CFA-74177 https://reactome.org/PathwayBrowser/#/R-CFA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Canis familiaris 4522 R-CFA-74180 https://reactome.org/PathwayBrowser/#/R-CFA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Canis familiaris 4522 R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 4522 R-DDI-74177 https://reactome.org/PathwayBrowser/#/R-DDI-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Dictyostelium discoideum 4522 R-DDI-74180 https://reactome.org/PathwayBrowser/#/R-DDI-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Dictyostelium discoideum 4522 R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 4522 R-DME-73912 https://reactome.org/PathwayBrowser/#/R-DME-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Drosophila melanogaster 4522 R-DME-73920 https://reactome.org/PathwayBrowser/#/R-DME-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Drosophila melanogaster 4522 R-DME-74177 https://reactome.org/PathwayBrowser/#/R-DME-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Drosophila melanogaster 4522 R-DME-74180 https://reactome.org/PathwayBrowser/#/R-DME-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Drosophila melanogaster 4522 R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 4522 R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 4522 R-DRE-73912 https://reactome.org/PathwayBrowser/#/R-DRE-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Danio rerio 4522 R-DRE-73920 https://reactome.org/PathwayBrowser/#/R-DRE-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Danio rerio 4522 R-DRE-74177 https://reactome.org/PathwayBrowser/#/R-DRE-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Danio rerio 4522 R-DRE-74180 https://reactome.org/PathwayBrowser/#/R-DRE-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Danio rerio 4522 R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 4522 R-GGA-73912 https://reactome.org/PathwayBrowser/#/R-GGA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Gallus gallus 4522 R-GGA-73920 https://reactome.org/PathwayBrowser/#/R-GGA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Gallus gallus 4522 R-GGA-74177 https://reactome.org/PathwayBrowser/#/R-GGA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Gallus gallus 4522 R-GGA-74180 https://reactome.org/PathwayBrowser/#/R-GGA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Gallus gallus 4522 R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 4522 R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 4522 R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 4522 R-HSA-73912 https://reactome.org/PathwayBrowser/#/R-HSA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ TAS Homo sapiens 4522 R-HSA-73920 https://reactome.org/PathwayBrowser/#/R-HSA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ TAS Homo sapiens 4522 R-HSA-74177 https://reactome.org/PathwayBrowser/#/R-HSA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA TAS Homo sapiens 4522 R-HSA-74180 https://reactome.org/PathwayBrowser/#/R-HSA-74180 HMG CoA => acetoacetic acid + acetyl CoA TAS Homo sapiens 4522 R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 4522 R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 4522 R-MMU-73912 https://reactome.org/PathwayBrowser/#/R-MMU-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Mus musculus 4522 R-MMU-73920 https://reactome.org/PathwayBrowser/#/R-MMU-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Mus musculus 4522 R-MMU-74177 https://reactome.org/PathwayBrowser/#/R-MMU-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Mus musculus 4522 R-MMU-74180 https://reactome.org/PathwayBrowser/#/R-MMU-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Mus musculus 4522 R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 4522 R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 4522 R-RNO-73912 https://reactome.org/PathwayBrowser/#/R-RNO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Rattus norvegicus 4522 R-RNO-73920 https://reactome.org/PathwayBrowser/#/R-RNO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Rattus norvegicus 4522 R-RNO-74177 https://reactome.org/PathwayBrowser/#/R-RNO-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Rattus norvegicus 4522 R-RNO-74180 https://reactome.org/PathwayBrowser/#/R-RNO-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Rattus norvegicus 4522 R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 4522 R-SPO-73912 https://reactome.org/PathwayBrowser/#/R-SPO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Schizosaccharomyces pombe 4522 R-SPO-73920 https://reactome.org/PathwayBrowser/#/R-SPO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Schizosaccharomyces pombe 4522 R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 4522 R-SSC-73912 https://reactome.org/PathwayBrowser/#/R-SSC-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Sus scrofa 4522 R-SSC-73920 https://reactome.org/PathwayBrowser/#/R-SSC-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Sus scrofa 4522 R-SSC-74177 https://reactome.org/PathwayBrowser/#/R-SSC-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Sus scrofa 4522 R-SSC-74180 https://reactome.org/PathwayBrowser/#/R-SSC-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Sus scrofa 4522 R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 4522 R-XTR-73912 https://reactome.org/PathwayBrowser/#/R-XTR-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Xenopus tropicalis 4522 R-XTR-73920 https://reactome.org/PathwayBrowser/#/R-XTR-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Xenopus tropicalis 4522 R-XTR-74177 https://reactome.org/PathwayBrowser/#/R-XTR-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Xenopus tropicalis 4522 R-XTR-74180 https://reactome.org/PathwayBrowser/#/R-XTR-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Xenopus tropicalis 4522 R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-BTA-1605591 https://reactome.org/PathwayBrowser/#/R-BTA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Bos taurus 4536 R-BTA-1606564 https://reactome.org/PathwayBrowser/#/R-BTA-1606564 GALC hydrolyzes GalCer IEA Bos taurus 4536 R-BTA-1861788 https://reactome.org/PathwayBrowser/#/R-BTA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Bos taurus 4536 R-BTA-1861789 https://reactome.org/PathwayBrowser/#/R-BTA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Bos taurus 4536 R-BTA-188979 https://reactome.org/PathwayBrowser/#/R-BTA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Bos taurus 4536 R-BTA-189053 https://reactome.org/PathwayBrowser/#/R-BTA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Bos taurus 4536 R-BTA-189062 https://reactome.org/PathwayBrowser/#/R-BTA-189062 lactose + H2O => D-glucose + D-galactose IEA Bos taurus 4536 R-BTA-189069 https://reactome.org/PathwayBrowser/#/R-BTA-189069 sucrose + H2O => glucose + fructose IEA Bos taurus 4536 R-BTA-189102 https://reactome.org/PathwayBrowser/#/R-BTA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Bos taurus 4536 R-BTA-189208 https://reactome.org/PathwayBrowser/#/R-BTA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-189242 https://reactome.org/PathwayBrowser/#/R-BTA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Bos taurus 4536 R-BTA-191101 https://reactome.org/PathwayBrowser/#/R-BTA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Bos taurus 4536 R-BTA-191108 https://reactome.org/PathwayBrowser/#/R-BTA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 4536 R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 4536 R-BTA-191116 https://reactome.org/PathwayBrowser/#/R-BTA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Bos taurus 4536 R-BTA-265682 https://reactome.org/PathwayBrowser/#/R-BTA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Bos taurus 4536 R-BTA-3262512 https://reactome.org/PathwayBrowser/#/R-BTA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Bos taurus 4536 R-BTA-3266566 https://reactome.org/PathwayBrowser/#/R-BTA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Bos taurus 4536 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 4536 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 4536 R-BTA-422048 https://reactome.org/PathwayBrowser/#/R-BTA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Bos taurus 4536 R-BTA-428779 https://reactome.org/PathwayBrowser/#/R-BTA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Bos taurus 4536 R-BTA-429036 https://reactome.org/PathwayBrowser/#/R-BTA-429036 SLC2A9 transports Fru, Glc, urate IEA Bos taurus 4536 R-BTA-429094 https://reactome.org/PathwayBrowser/#/R-BTA-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-429567 https://reactome.org/PathwayBrowser/#/R-BTA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Bos taurus 4536 R-BTA-429613 https://reactome.org/PathwayBrowser/#/R-BTA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 4536 R-BTA-450095 https://reactome.org/PathwayBrowser/#/R-BTA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Bos taurus 4536 R-BTA-499981 https://reactome.org/PathwayBrowser/#/R-BTA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Bos taurus 4536 R-BTA-5339524 https://reactome.org/PathwayBrowser/#/R-BTA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-5652172 https://reactome.org/PathwayBrowser/#/R-BTA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Bos taurus 4536 R-BTA-5653873 https://reactome.org/PathwayBrowser/#/R-BTA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Bos taurus 4536 R-BTA-5653878 https://reactome.org/PathwayBrowser/#/R-BTA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Bos taurus 4536 R-BTA-5659861 https://reactome.org/PathwayBrowser/#/R-BTA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 4536 R-BTA-5696021 https://reactome.org/PathwayBrowser/#/R-BTA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Bos taurus 4536 R-BTA-70420 https://reactome.org/PathwayBrowser/#/R-BTA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Bos taurus 4536 R-BTA-71593 https://reactome.org/PathwayBrowser/#/R-BTA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Bos taurus 4536 R-BTA-71825 https://reactome.org/PathwayBrowser/#/R-BTA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Bos taurus 4536 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 4536 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 4536 R-BTA-8875902 https://reactome.org/PathwayBrowser/#/R-BTA-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-8932955 https://reactome.org/PathwayBrowser/#/R-BTA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-8981553 https://reactome.org/PathwayBrowser/#/R-BTA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-8981564 https://reactome.org/PathwayBrowser/#/R-BTA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-8981570 https://reactome.org/PathwayBrowser/#/R-BTA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-8981574 https://reactome.org/PathwayBrowser/#/R-BTA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Bos taurus 4536 R-BTA-9036727 https://reactome.org/PathwayBrowser/#/R-BTA-9036727 GAA hydrolyzes lysosomal glycogen IEA Bos taurus 4536 R-BTA-964759 https://reactome.org/PathwayBrowser/#/R-BTA-964759 Alternative endo-mannosidase I route IEA Bos taurus 4536 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 4536 R-CEL-1605591 https://reactome.org/PathwayBrowser/#/R-CEL-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Caenorhabditis elegans 4536 R-CEL-1606564 https://reactome.org/PathwayBrowser/#/R-CEL-1606564 GALC hydrolyzes GalCer IEA Caenorhabditis elegans 4536 R-CEL-1861788 https://reactome.org/PathwayBrowser/#/R-CEL-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Caenorhabditis elegans 4536 R-CEL-1861789 https://reactome.org/PathwayBrowser/#/R-CEL-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Caenorhabditis elegans 4536 R-CEL-188979 https://reactome.org/PathwayBrowser/#/R-CEL-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Caenorhabditis elegans 4536 R-CEL-189053 https://reactome.org/PathwayBrowser/#/R-CEL-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Caenorhabditis elegans 4536 R-CEL-189062 https://reactome.org/PathwayBrowser/#/R-CEL-189062 lactose + H2O => D-glucose + D-galactose IEA Caenorhabditis elegans 4536 R-CEL-189069 https://reactome.org/PathwayBrowser/#/R-CEL-189069 sucrose + H2O => glucose + fructose IEA Caenorhabditis elegans 4536 R-CEL-189102 https://reactome.org/PathwayBrowser/#/R-CEL-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 4536 R-CEL-189242 https://reactome.org/PathwayBrowser/#/R-CEL-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Caenorhabditis elegans 4536 R-CEL-191101 https://reactome.org/PathwayBrowser/#/R-CEL-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 4536 R-CEL-191108 https://reactome.org/PathwayBrowser/#/R-CEL-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 4536 R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 4536 R-CEL-191116 https://reactome.org/PathwayBrowser/#/R-CEL-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 4536 R-CEL-428779 https://reactome.org/PathwayBrowser/#/R-CEL-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Caenorhabditis elegans 4536 R-CEL-429036 https://reactome.org/PathwayBrowser/#/R-CEL-429036 SLC2A9 transports Fru, Glc, urate IEA Caenorhabditis elegans 4536 R-CEL-450095 https://reactome.org/PathwayBrowser/#/R-CEL-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Caenorhabditis elegans 4536 R-CEL-499981 https://reactome.org/PathwayBrowser/#/R-CEL-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Caenorhabditis elegans 4536 R-CEL-5339524 https://reactome.org/PathwayBrowser/#/R-CEL-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 4536 R-CEL-5652172 https://reactome.org/PathwayBrowser/#/R-CEL-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Caenorhabditis elegans 4536 R-CEL-5653873 https://reactome.org/PathwayBrowser/#/R-CEL-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Caenorhabditis elegans 4536 R-CEL-5659861 https://reactome.org/PathwayBrowser/#/R-CEL-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 4536 R-CEL-5696021 https://reactome.org/PathwayBrowser/#/R-CEL-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Caenorhabditis elegans 4536 R-CEL-70420 https://reactome.org/PathwayBrowser/#/R-CEL-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Caenorhabditis elegans 4536 R-CEL-71593 https://reactome.org/PathwayBrowser/#/R-CEL-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Caenorhabditis elegans 4536 R-CEL-8981553 https://reactome.org/PathwayBrowser/#/R-CEL-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 4536 R-CEL-8981564 https://reactome.org/PathwayBrowser/#/R-CEL-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 4536 R-CEL-8981570 https://reactome.org/PathwayBrowser/#/R-CEL-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 4536 R-CEL-8981574 https://reactome.org/PathwayBrowser/#/R-CEL-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Caenorhabditis elegans 4536 R-CFA-1605591 https://reactome.org/PathwayBrowser/#/R-CFA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Canis familiaris 4536 R-CFA-1606564 https://reactome.org/PathwayBrowser/#/R-CFA-1606564 GALC hydrolyzes GalCer IEA Canis familiaris 4536 R-CFA-170810 https://reactome.org/PathwayBrowser/#/R-CFA-170810 nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) IEA Canis familiaris 4536 R-CFA-1861788 https://reactome.org/PathwayBrowser/#/R-CFA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Canis familiaris 4536 R-CFA-1861789 https://reactome.org/PathwayBrowser/#/R-CFA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Canis familiaris 4536 R-CFA-188979 https://reactome.org/PathwayBrowser/#/R-CFA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Canis familiaris 4536 R-CFA-189053 https://reactome.org/PathwayBrowser/#/R-CFA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Canis familiaris 4536 R-CFA-189062 https://reactome.org/PathwayBrowser/#/R-CFA-189062 lactose + H2O => D-glucose + D-galactose IEA Canis familiaris 4536 R-CFA-189069 https://reactome.org/PathwayBrowser/#/R-CFA-189069 sucrose + H2O => glucose + fructose IEA Canis familiaris 4536 R-CFA-189102 https://reactome.org/PathwayBrowser/#/R-CFA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Canis familiaris 4536 R-CFA-189208 https://reactome.org/PathwayBrowser/#/R-CFA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-189242 https://reactome.org/PathwayBrowser/#/R-CFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Canis familiaris 4536 R-CFA-191101 https://reactome.org/PathwayBrowser/#/R-CFA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Canis familiaris 4536 R-CFA-191108 https://reactome.org/PathwayBrowser/#/R-CFA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 4536 R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 4536 R-CFA-191116 https://reactome.org/PathwayBrowser/#/R-CFA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Canis familiaris 4536 R-CFA-265682 https://reactome.org/PathwayBrowser/#/R-CFA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Canis familiaris 4536 R-CFA-3262512 https://reactome.org/PathwayBrowser/#/R-CFA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Canis familiaris 4536 R-CFA-3266566 https://reactome.org/PathwayBrowser/#/R-CFA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Canis familiaris 4536 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 4536 R-CFA-422048 https://reactome.org/PathwayBrowser/#/R-CFA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Canis familiaris 4536 R-CFA-428779 https://reactome.org/PathwayBrowser/#/R-CFA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Canis familiaris 4536 R-CFA-429036 https://reactome.org/PathwayBrowser/#/R-CFA-429036 SLC2A9 transports Fru, Glc, urate IEA Canis familiaris 4536 R-CFA-429094 https://reactome.org/PathwayBrowser/#/R-CFA-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-429567 https://reactome.org/PathwayBrowser/#/R-CFA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Canis familiaris 4536 R-CFA-429613 https://reactome.org/PathwayBrowser/#/R-CFA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-450095 https://reactome.org/PathwayBrowser/#/R-CFA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Canis familiaris 4536 R-CFA-499981 https://reactome.org/PathwayBrowser/#/R-CFA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Canis familiaris 4536 R-CFA-5339524 https://reactome.org/PathwayBrowser/#/R-CFA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-5652172 https://reactome.org/PathwayBrowser/#/R-CFA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Canis familiaris 4536 R-CFA-5653873 https://reactome.org/PathwayBrowser/#/R-CFA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Canis familiaris 4536 R-CFA-5653878 https://reactome.org/PathwayBrowser/#/R-CFA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Canis familiaris 4536 R-CFA-5659861 https://reactome.org/PathwayBrowser/#/R-CFA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 4536 R-CFA-5696021 https://reactome.org/PathwayBrowser/#/R-CFA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Canis familiaris 4536 R-CFA-70420 https://reactome.org/PathwayBrowser/#/R-CFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Canis familiaris 4536 R-CFA-71593 https://reactome.org/PathwayBrowser/#/R-CFA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Canis familiaris 4536 R-CFA-71825 https://reactome.org/PathwayBrowser/#/R-CFA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Canis familiaris 4536 R-CFA-8875902 https://reactome.org/PathwayBrowser/#/R-CFA-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-8876319 https://reactome.org/PathwayBrowser/#/R-CFA-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Canis familiaris 4536 R-CFA-8932955 https://reactome.org/PathwayBrowser/#/R-CFA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-8981553 https://reactome.org/PathwayBrowser/#/R-CFA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-8981564 https://reactome.org/PathwayBrowser/#/R-CFA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-8981570 https://reactome.org/PathwayBrowser/#/R-CFA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-8981574 https://reactome.org/PathwayBrowser/#/R-CFA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Canis familiaris 4536 R-CFA-9036727 https://reactome.org/PathwayBrowser/#/R-CFA-9036727 GAA hydrolyzes lysosomal glycogen IEA Canis familiaris 4536 R-CFA-964759 https://reactome.org/PathwayBrowser/#/R-CFA-964759 Alternative endo-mannosidase I route IEA Canis familiaris 4536 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 4536 R-DDI-1861788 https://reactome.org/PathwayBrowser/#/R-DDI-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Dictyostelium discoideum 4536 R-DDI-189053 https://reactome.org/PathwayBrowser/#/R-DDI-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Dictyostelium discoideum 4536 R-DDI-189069 https://reactome.org/PathwayBrowser/#/R-DDI-189069 sucrose + H2O => glucose + fructose IEA Dictyostelium discoideum 4536 R-DDI-189102 https://reactome.org/PathwayBrowser/#/R-DDI-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 4536 R-DDI-189242 https://reactome.org/PathwayBrowser/#/R-DDI-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Dictyostelium discoideum 4536 R-DDI-191101 https://reactome.org/PathwayBrowser/#/R-DDI-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 4536 R-DDI-191108 https://reactome.org/PathwayBrowser/#/R-DDI-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 4536 R-DDI-191116 https://reactome.org/PathwayBrowser/#/R-DDI-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 4536 R-DDI-428779 https://reactome.org/PathwayBrowser/#/R-DDI-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Dictyostelium discoideum 4536 R-DDI-429036 https://reactome.org/PathwayBrowser/#/R-DDI-429036 SLC2A9 transports Fru, Glc, urate IEA Dictyostelium discoideum 4536 R-DDI-429094 https://reactome.org/PathwayBrowser/#/R-DDI-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Dictyostelium discoideum 4536 R-DDI-450095 https://reactome.org/PathwayBrowser/#/R-DDI-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Dictyostelium discoideum 4536 R-DDI-499981 https://reactome.org/PathwayBrowser/#/R-DDI-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Dictyostelium discoideum 4536 R-DDI-5339524 https://reactome.org/PathwayBrowser/#/R-DDI-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 4536 R-DDI-5652172 https://reactome.org/PathwayBrowser/#/R-DDI-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Dictyostelium discoideum 4536 R-DDI-5653873 https://reactome.org/PathwayBrowser/#/R-DDI-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Dictyostelium discoideum 4536 R-DDI-5659861 https://reactome.org/PathwayBrowser/#/R-DDI-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 4536 R-DDI-5696021 https://reactome.org/PathwayBrowser/#/R-DDI-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Dictyostelium discoideum 4536 R-DDI-71593 https://reactome.org/PathwayBrowser/#/R-DDI-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Dictyostelium discoideum 4536 R-DDI-8875902 https://reactome.org/PathwayBrowser/#/R-DDI-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 4536 R-DDI-8876319 https://reactome.org/PathwayBrowser/#/R-DDI-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Dictyostelium discoideum 4536 R-DDI-8981553 https://reactome.org/PathwayBrowser/#/R-DDI-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 4536 R-DDI-8981564 https://reactome.org/PathwayBrowser/#/R-DDI-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 4536 R-DDI-8981570 https://reactome.org/PathwayBrowser/#/R-DDI-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 4536 R-DDI-8981574 https://reactome.org/PathwayBrowser/#/R-DDI-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Dictyostelium discoideum 4536 R-DDI-9036727 https://reactome.org/PathwayBrowser/#/R-DDI-9036727 GAA hydrolyzes lysosomal glycogen IEA Dictyostelium discoideum 4536 R-DME-1605591 https://reactome.org/PathwayBrowser/#/R-DME-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Drosophila melanogaster 4536 R-DME-1861788 https://reactome.org/PathwayBrowser/#/R-DME-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Drosophila melanogaster 4536 R-DME-1861789 https://reactome.org/PathwayBrowser/#/R-DME-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Drosophila melanogaster 4536 R-DME-188979 https://reactome.org/PathwayBrowser/#/R-DME-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Drosophila melanogaster 4536 R-DME-189062 https://reactome.org/PathwayBrowser/#/R-DME-189062 lactose + H2O => D-glucose + D-galactose IEA Drosophila melanogaster 4536 R-DME-189242 https://reactome.org/PathwayBrowser/#/R-DME-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Drosophila melanogaster 4536 R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 4536 R-DME-265682 https://reactome.org/PathwayBrowser/#/R-DME-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Drosophila melanogaster 4536 R-DME-3262512 https://reactome.org/PathwayBrowser/#/R-DME-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Drosophila melanogaster 4536 R-DME-3266566 https://reactome.org/PathwayBrowser/#/R-DME-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Drosophila melanogaster 4536 R-DME-428779 https://reactome.org/PathwayBrowser/#/R-DME-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Drosophila melanogaster 4536 R-DME-429036 https://reactome.org/PathwayBrowser/#/R-DME-429036 SLC2A9 transports Fru, Glc, urate IEA Drosophila melanogaster 4536 R-DME-429094 https://reactome.org/PathwayBrowser/#/R-DME-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Drosophila melanogaster 4536 R-DME-450095 https://reactome.org/PathwayBrowser/#/R-DME-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Drosophila melanogaster 4536 R-DME-499981 https://reactome.org/PathwayBrowser/#/R-DME-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Drosophila melanogaster 4536 R-DME-5339524 https://reactome.org/PathwayBrowser/#/R-DME-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 4536 R-DME-5652172 https://reactome.org/PathwayBrowser/#/R-DME-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Drosophila melanogaster 4536 R-DME-5653873 https://reactome.org/PathwayBrowser/#/R-DME-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Drosophila melanogaster 4536 R-DME-5653878 https://reactome.org/PathwayBrowser/#/R-DME-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Drosophila melanogaster 4536 R-DME-70420 https://reactome.org/PathwayBrowser/#/R-DME-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Drosophila melanogaster 4536 R-DME-71593 https://reactome.org/PathwayBrowser/#/R-DME-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Drosophila melanogaster 4536 R-DME-71825 https://reactome.org/PathwayBrowser/#/R-DME-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Drosophila melanogaster 4536 R-DME-8981553 https://reactome.org/PathwayBrowser/#/R-DME-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 4536 R-DME-8981564 https://reactome.org/PathwayBrowser/#/R-DME-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 4536 R-DME-8981570 https://reactome.org/PathwayBrowser/#/R-DME-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 4536 R-DME-8981574 https://reactome.org/PathwayBrowser/#/R-DME-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Drosophila melanogaster 4536 R-DME-964759 https://reactome.org/PathwayBrowser/#/R-DME-964759 Alternative endo-mannosidase I route IEA Drosophila melanogaster 4536 R-DRE-1861788 https://reactome.org/PathwayBrowser/#/R-DRE-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Danio rerio 4536 R-DRE-1861789 https://reactome.org/PathwayBrowser/#/R-DRE-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Danio rerio 4536 R-DRE-188979 https://reactome.org/PathwayBrowser/#/R-DRE-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Danio rerio 4536 R-DRE-189208 https://reactome.org/PathwayBrowser/#/R-DRE-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-189242 https://reactome.org/PathwayBrowser/#/R-DRE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Danio rerio 4536 R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 4536 R-DRE-3262512 https://reactome.org/PathwayBrowser/#/R-DRE-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Danio rerio 4536 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 4536 R-DRE-422048 https://reactome.org/PathwayBrowser/#/R-DRE-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Danio rerio 4536 R-DRE-429094 https://reactome.org/PathwayBrowser/#/R-DRE-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-429567 https://reactome.org/PathwayBrowser/#/R-DRE-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Danio rerio 4536 R-DRE-429613 https://reactome.org/PathwayBrowser/#/R-DRE-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 4536 R-DRE-450095 https://reactome.org/PathwayBrowser/#/R-DRE-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Danio rerio 4536 R-DRE-499981 https://reactome.org/PathwayBrowser/#/R-DRE-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Danio rerio 4536 R-DRE-5339524 https://reactome.org/PathwayBrowser/#/R-DRE-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-5652172 https://reactome.org/PathwayBrowser/#/R-DRE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Danio rerio 4536 R-DRE-5653873 https://reactome.org/PathwayBrowser/#/R-DRE-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Danio rerio 4536 R-DRE-5653878 https://reactome.org/PathwayBrowser/#/R-DRE-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Danio rerio 4536 R-DRE-5696021 https://reactome.org/PathwayBrowser/#/R-DRE-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Danio rerio 4536 R-DRE-70420 https://reactome.org/PathwayBrowser/#/R-DRE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Danio rerio 4536 R-DRE-8875902 https://reactome.org/PathwayBrowser/#/R-DRE-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-8876319 https://reactome.org/PathwayBrowser/#/R-DRE-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Danio rerio 4536 R-DRE-8932955 https://reactome.org/PathwayBrowser/#/R-DRE-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-8981553 https://reactome.org/PathwayBrowser/#/R-DRE-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-8981564 https://reactome.org/PathwayBrowser/#/R-DRE-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-8981574 https://reactome.org/PathwayBrowser/#/R-DRE-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Danio rerio 4536 R-DRE-964759 https://reactome.org/PathwayBrowser/#/R-DRE-964759 Alternative endo-mannosidase I route IEA Danio rerio 4536 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 4536 R-GGA-1605591 https://reactome.org/PathwayBrowser/#/R-GGA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Gallus gallus 4536 R-GGA-1606564 https://reactome.org/PathwayBrowser/#/R-GGA-1606564 GALC hydrolyzes GalCer IEA Gallus gallus 4536 R-GGA-1861788 https://reactome.org/PathwayBrowser/#/R-GGA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Gallus gallus 4536 R-GGA-188979 https://reactome.org/PathwayBrowser/#/R-GGA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Gallus gallus 4536 R-GGA-189053 https://reactome.org/PathwayBrowser/#/R-GGA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Gallus gallus 4536 R-GGA-189062 https://reactome.org/PathwayBrowser/#/R-GGA-189062 lactose + H2O => D-glucose + D-galactose IEA Gallus gallus 4536 R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus 4536 R-GGA-189102 https://reactome.org/PathwayBrowser/#/R-GGA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Gallus gallus 4536 R-GGA-189242 https://reactome.org/PathwayBrowser/#/R-GGA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Gallus gallus 4536 R-GGA-191101 https://reactome.org/PathwayBrowser/#/R-GGA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Gallus gallus 4536 R-GGA-191108 https://reactome.org/PathwayBrowser/#/R-GGA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 4536 R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 4536 R-GGA-191116 https://reactome.org/PathwayBrowser/#/R-GGA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Gallus gallus 4536 R-GGA-265682 https://reactome.org/PathwayBrowser/#/R-GGA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Gallus gallus 4536 R-GGA-3262512 https://reactome.org/PathwayBrowser/#/R-GGA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Gallus gallus 4536 R-GGA-3266566 https://reactome.org/PathwayBrowser/#/R-GGA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Gallus gallus 4536 R-GGA-352840 https://reactome.org/PathwayBrowser/#/R-GGA-352840 glucose + ATP => glucose 6-phosphate + ADP TAS Gallus gallus 4536 R-GGA-352864 https://reactome.org/PathwayBrowser/#/R-GGA-352864 glucose [extracellular] <=> glucose [cytosol] TAS Gallus gallus 4536 R-GGA-352867 https://reactome.org/PathwayBrowser/#/R-GGA-352867 glucose [cytosol] <=> glucose [extracellular] TAS Gallus gallus 4536 R-GGA-353058 https://reactome.org/PathwayBrowser/#/R-GGA-353058 glucose 6-phosphate + H2O => glucose + phosphate IEA Gallus gallus 4536 R-GGA-376886 https://reactome.org/PathwayBrowser/#/R-GGA-376886 Efflux of glucose and orthophosphate from the endoplasmic reticulum TAS Gallus gallus 4536 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 4536 R-GGA-422048 https://reactome.org/PathwayBrowser/#/R-GGA-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Gallus gallus 4536 R-GGA-428779 https://reactome.org/PathwayBrowser/#/R-GGA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Gallus gallus 4536 R-GGA-429036 https://reactome.org/PathwayBrowser/#/R-GGA-429036 SLC2A9 transports Fru, Glc, urate IEA Gallus gallus 4536 R-GGA-429094 https://reactome.org/PathwayBrowser/#/R-GGA-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Gallus gallus 4536 R-GGA-429567 https://reactome.org/PathwayBrowser/#/R-GGA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Gallus gallus 4536 R-GGA-450095 https://reactome.org/PathwayBrowser/#/R-GGA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Gallus gallus 4536 R-GGA-499981 https://reactome.org/PathwayBrowser/#/R-GGA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Gallus gallus 4536 R-GGA-5339524 https://reactome.org/PathwayBrowser/#/R-GGA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 4536 R-GGA-5652172 https://reactome.org/PathwayBrowser/#/R-GGA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Gallus gallus 4536 R-GGA-5653873 https://reactome.org/PathwayBrowser/#/R-GGA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Gallus gallus 4536 R-GGA-5653878 https://reactome.org/PathwayBrowser/#/R-GGA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Gallus gallus 4536 R-GGA-5659861 https://reactome.org/PathwayBrowser/#/R-GGA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 4536 R-GGA-5696021 https://reactome.org/PathwayBrowser/#/R-GGA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Gallus gallus 4536 R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus 4536 R-GGA-71593 https://reactome.org/PathwayBrowser/#/R-GGA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Gallus gallus 4536 R-GGA-71825 https://reactome.org/PathwayBrowser/#/R-GGA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Gallus gallus 4536 R-GGA-8875902 https://reactome.org/PathwayBrowser/#/R-GGA-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Gallus gallus 4536 R-GGA-8932955 https://reactome.org/PathwayBrowser/#/R-GGA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Gallus gallus 4536 R-GGA-8981553 https://reactome.org/PathwayBrowser/#/R-GGA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 4536 R-GGA-8981564 https://reactome.org/PathwayBrowser/#/R-GGA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 4536 R-GGA-8981570 https://reactome.org/PathwayBrowser/#/R-GGA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 4536 R-GGA-8981574 https://reactome.org/PathwayBrowser/#/R-GGA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Gallus gallus 4536 R-GGA-964759 https://reactome.org/PathwayBrowser/#/R-GGA-964759 Alternative endo-mannosidase I route IEA Gallus gallus 4536 R-HSA-1605591 https://reactome.org/PathwayBrowser/#/R-HSA-1605591 GBA1:SAPC hydrolyzes GlcCer TAS Homo sapiens 4536 R-HSA-1606564 https://reactome.org/PathwayBrowser/#/R-HSA-1606564 GALC hydrolyzes GalCer TAS Homo sapiens 4536 R-HSA-170810 https://reactome.org/PathwayBrowser/#/R-HSA-170810 nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) TAS Homo sapiens 4536 R-HSA-1861788 https://reactome.org/PathwayBrowser/#/R-HSA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) TAS Homo sapiens 4536 R-HSA-1861789 https://reactome.org/PathwayBrowser/#/R-HSA-1861789 GBA3 hydrolyzes GlcCer (cytosol) TAS Homo sapiens 4536 R-HSA-188979 https://reactome.org/PathwayBrowser/#/R-HSA-188979 Digestion of linear starch (amylose) by extracellular amylase TAS Homo sapiens 4536 R-HSA-188985 https://reactome.org/PathwayBrowser/#/R-HSA-188985 trehalose + H2O => 2 D-glucose IEA Homo sapiens 4536 R-HSA-189053 https://reactome.org/PathwayBrowser/#/R-HSA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose TAS Homo sapiens 4536 R-HSA-189062 https://reactome.org/PathwayBrowser/#/R-HSA-189062 lactose + H2O => D-glucose + D-galactose TAS Homo sapiens 4536 R-HSA-189069 https://reactome.org/PathwayBrowser/#/R-HSA-189069 sucrose + H2O => glucose + fructose TAS Homo sapiens 4536 R-HSA-189102 https://reactome.org/PathwayBrowser/#/R-HSA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) TAS Homo sapiens 4536 R-HSA-189208 https://reactome.org/PathwayBrowser/#/R-HSA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-189242 https://reactome.org/PathwayBrowser/#/R-HSA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 4536 R-HSA-191101 https://reactome.org/PathwayBrowser/#/R-HSA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) TAS Homo sapiens 4536 R-HSA-191108 https://reactome.org/PathwayBrowser/#/R-HSA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 4536 R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 4536 R-HSA-191116 https://reactome.org/PathwayBrowser/#/R-HSA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) TAS Homo sapiens 4536 R-HSA-198458 https://reactome.org/PathwayBrowser/#/R-HSA-198458 Efflux of Glc from the endoplasmic reticulum TAS Homo sapiens 4536 R-HSA-265682 https://reactome.org/PathwayBrowser/#/R-HSA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel TAS Homo sapiens 4536 R-HSA-3262512 https://reactome.org/PathwayBrowser/#/R-HSA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) TAS Homo sapiens 4536 R-HSA-3266566 https://reactome.org/PathwayBrowser/#/R-HSA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) TAS Homo sapiens 4536 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 4536 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 4536 R-HSA-422048 https://reactome.org/PathwayBrowser/#/R-HSA-422048 Acyl Ghrelin and C-Ghrelin are secreted TAS Homo sapiens 4536 R-HSA-428779 https://reactome.org/PathwayBrowser/#/R-HSA-428779 GLUT7 and GLUT11 transport glucose and fructose TAS Homo sapiens 4536 R-HSA-429036 https://reactome.org/PathwayBrowser/#/R-HSA-429036 SLC2A9 transports Fru, Glc, urate TAS Homo sapiens 4536 R-HSA-429094 https://reactome.org/PathwayBrowser/#/R-HSA-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-429567 https://reactome.org/PathwayBrowser/#/R-HSA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 TAS Homo sapiens 4536 R-HSA-429613 https://reactome.org/PathwayBrowser/#/R-HSA-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 4536 R-HSA-450095 https://reactome.org/PathwayBrowser/#/R-HSA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region TAS Homo sapiens 4536 R-HSA-499981 https://reactome.org/PathwayBrowser/#/R-HSA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 TAS Homo sapiens 4536 R-HSA-532667 https://reactome.org/PathwayBrowser/#/R-HSA-532667 Removal of the second glucose by glucosidase II TAS Homo sapiens 4536 R-HSA-532678 https://reactome.org/PathwayBrowser/#/R-HSA-532678 Trimming of the first glucose by by mannosyl-oligosaccharide glucosidase TAS Homo sapiens 4536 R-HSA-5339524 https://reactome.org/PathwayBrowser/#/R-HSA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-548890 https://reactome.org/PathwayBrowser/#/R-HSA-548890 Removal of the third glucose by glucosidase II and release from the chaperone TAS Homo sapiens 4536 R-HSA-5621888 https://reactome.org/PathwayBrowser/#/R-HSA-5621888 Defective HK1 does not phosphorylate Glc to form G6P TAS Homo sapiens 4536 R-HSA-5621918 https://reactome.org/PathwayBrowser/#/R-HSA-5621918 Defective GCK does not phosphorylate Glc to form G6P TAS Homo sapiens 4536 R-HSA-5632804 https://reactome.org/PathwayBrowser/#/R-HSA-5632804 SLC2A1 tetramer does not transport Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-5632871 https://reactome.org/PathwayBrowser/#/R-HSA-5632871 Defective SLC2A10 does not transport Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-5638209 https://reactome.org/PathwayBrowser/#/R-HSA-5638209 Defective SLC2A9 does not transport Fru, Glc, urate TAS Homo sapiens 4536 R-HSA-5638222 https://reactome.org/PathwayBrowser/#/R-HSA-5638222 Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 4536 R-HSA-5652172 https://reactome.org/PathwayBrowser/#/R-HSA-5652172 AKR1B1 reduces Glc to D-sorbitol TAS Homo sapiens 4536 R-HSA-5653873 https://reactome.org/PathwayBrowser/#/R-HSA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen TAS Homo sapiens 4536 R-HSA-5653878 https://reactome.org/PathwayBrowser/#/R-HSA-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac TAS Homo sapiens 4536 R-HSA-5656356 https://reactome.org/PathwayBrowser/#/R-HSA-5656356 Defective SLC5A1 does not cotransport Glc and Na+ TAS Homo sapiens 4536 R-HSA-5658163 https://reactome.org/PathwayBrowser/#/R-HSA-5658163 Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-5659861 https://reactome.org/PathwayBrowser/#/R-HSA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 4536 R-HSA-5696021 https://reactome.org/PathwayBrowser/#/R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P TAS Homo sapiens 4536 R-HSA-70420 https://reactome.org/PathwayBrowser/#/R-HSA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P TAS Homo sapiens 4536 R-HSA-71593 https://reactome.org/PathwayBrowser/#/R-HSA-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose TAS Homo sapiens 4536 R-HSA-71825 https://reactome.org/PathwayBrowser/#/R-HSA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) TAS Homo sapiens 4536 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 4536 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 4536 R-HSA-8875902 https://reactome.org/PathwayBrowser/#/R-HSA-8875902 SLC45A3 transports Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-8876319 https://reactome.org/PathwayBrowser/#/R-HSA-8876319 SLC50A1 transports Glc from cytosol to extracellular region TAS Homo sapiens 4536 R-HSA-8932955 https://reactome.org/PathwayBrowser/#/R-HSA-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-8981553 https://reactome.org/PathwayBrowser/#/R-HSA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-8981564 https://reactome.org/PathwayBrowser/#/R-HSA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-8981570 https://reactome.org/PathwayBrowser/#/R-HSA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-8981574 https://reactome.org/PathwayBrowser/#/R-HSA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol TAS Homo sapiens 4536 R-HSA-9036727 https://reactome.org/PathwayBrowser/#/R-HSA-9036727 GAA hydrolyzes lysosomal glycogen TAS Homo sapiens 4536 R-HSA-964759 https://reactome.org/PathwayBrowser/#/R-HSA-964759 Alternative endo-mannosidase I route TAS Homo sapiens 4536 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 4536 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 4536 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 4536 R-MMU-1605591 https://reactome.org/PathwayBrowser/#/R-MMU-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Mus musculus 4536 R-MMU-1606564 https://reactome.org/PathwayBrowser/#/R-MMU-1606564 GALC hydrolyzes GalCer IEA Mus musculus 4536 R-MMU-170810 https://reactome.org/PathwayBrowser/#/R-MMU-170810 nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) IEA Mus musculus 4536 R-MMU-1861788 https://reactome.org/PathwayBrowser/#/R-MMU-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Mus musculus 4536 R-MMU-188979 https://reactome.org/PathwayBrowser/#/R-MMU-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Mus musculus 4536 R-MMU-189053 https://reactome.org/PathwayBrowser/#/R-MMU-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Mus musculus 4536 R-MMU-189062 https://reactome.org/PathwayBrowser/#/R-MMU-189062 lactose + H2O => D-glucose + D-galactose IEA Mus musculus 4536 R-MMU-189069 https://reactome.org/PathwayBrowser/#/R-MMU-189069 sucrose + H2O => glucose + fructose IEA Mus musculus 4536 R-MMU-189102 https://reactome.org/PathwayBrowser/#/R-MMU-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Mus musculus 4536 R-MMU-189208 https://reactome.org/PathwayBrowser/#/R-MMU-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-189242 https://reactome.org/PathwayBrowser/#/R-MMU-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Mus musculus 4536 R-MMU-191101 https://reactome.org/PathwayBrowser/#/R-MMU-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Mus musculus 4536 R-MMU-191108 https://reactome.org/PathwayBrowser/#/R-MMU-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 4536 R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 4536 R-MMU-191116 https://reactome.org/PathwayBrowser/#/R-MMU-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Mus musculus 4536 R-MMU-265682 https://reactome.org/PathwayBrowser/#/R-MMU-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Mus musculus 4536 R-MMU-3262512 https://reactome.org/PathwayBrowser/#/R-MMU-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Mus musculus 4536 R-MMU-3266566 https://reactome.org/PathwayBrowser/#/R-MMU-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Mus musculus 4536 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 4536 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 4536 R-MMU-422048 https://reactome.org/PathwayBrowser/#/R-MMU-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Mus musculus 4536 R-MMU-428779 https://reactome.org/PathwayBrowser/#/R-MMU-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Mus musculus 4536 R-MMU-429036 https://reactome.org/PathwayBrowser/#/R-MMU-429036 SLC2A9 transports Fru, Glc, urate IEA Mus musculus 4536 R-MMU-429094 https://reactome.org/PathwayBrowser/#/R-MMU-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-429567 https://reactome.org/PathwayBrowser/#/R-MMU-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Mus musculus 4536 R-MMU-429613 https://reactome.org/PathwayBrowser/#/R-MMU-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 4536 R-MMU-450095 https://reactome.org/PathwayBrowser/#/R-MMU-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Mus musculus 4536 R-MMU-499981 https://reactome.org/PathwayBrowser/#/R-MMU-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Mus musculus 4536 R-MMU-5339524 https://reactome.org/PathwayBrowser/#/R-MMU-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-5652172 https://reactome.org/PathwayBrowser/#/R-MMU-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Mus musculus 4536 R-MMU-5653873 https://reactome.org/PathwayBrowser/#/R-MMU-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Mus musculus 4536 R-MMU-5653878 https://reactome.org/PathwayBrowser/#/R-MMU-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Mus musculus 4536 R-MMU-5659861 https://reactome.org/PathwayBrowser/#/R-MMU-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 4536 R-MMU-5696021 https://reactome.org/PathwayBrowser/#/R-MMU-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Mus musculus 4536 R-MMU-70420 https://reactome.org/PathwayBrowser/#/R-MMU-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Mus musculus 4536 R-MMU-71593 https://reactome.org/PathwayBrowser/#/R-MMU-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Mus musculus 4536 R-MMU-71825 https://reactome.org/PathwayBrowser/#/R-MMU-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Mus musculus 4536 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 4536 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 4536 R-MMU-8875902 https://reactome.org/PathwayBrowser/#/R-MMU-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-8876319 https://reactome.org/PathwayBrowser/#/R-MMU-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Mus musculus 4536 R-MMU-8932955 https://reactome.org/PathwayBrowser/#/R-MMU-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-8981553 https://reactome.org/PathwayBrowser/#/R-MMU-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-8981564 https://reactome.org/PathwayBrowser/#/R-MMU-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-8981570 https://reactome.org/PathwayBrowser/#/R-MMU-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-8981574 https://reactome.org/PathwayBrowser/#/R-MMU-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Mus musculus 4536 R-MMU-9036727 https://reactome.org/PathwayBrowser/#/R-MMU-9036727 GAA hydrolyzes lysosomal glycogen IEA Mus musculus 4536 R-MMU-964759 https://reactome.org/PathwayBrowser/#/R-MMU-964759 Alternative endo-mannosidase I route IEA Mus musculus 4536 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 4536 R-OCU-189019 https://reactome.org/PathwayBrowser/#/R-OCU-189019 trehalose + H2O => 2 D-glucose TAS Oryctolagus cuniculus 4536 R-PFA-189242 https://reactome.org/PathwayBrowser/#/R-PFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Plasmodium falciparum 4536 R-PFA-428779 https://reactome.org/PathwayBrowser/#/R-PFA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Plasmodium falciparum 4536 R-PFA-429036 https://reactome.org/PathwayBrowser/#/R-PFA-429036 SLC2A9 transports Fru, Glc, urate IEA Plasmodium falciparum 4536 R-PFA-450095 https://reactome.org/PathwayBrowser/#/R-PFA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Plasmodium falciparum 4536 R-PFA-499981 https://reactome.org/PathwayBrowser/#/R-PFA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Plasmodium falciparum 4536 R-PFA-5339524 https://reactome.org/PathwayBrowser/#/R-PFA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 4536 R-PFA-5653873 https://reactome.org/PathwayBrowser/#/R-PFA-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Plasmodium falciparum 4536 R-PFA-70420 https://reactome.org/PathwayBrowser/#/R-PFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Plasmodium falciparum 4536 R-PFA-8876319 https://reactome.org/PathwayBrowser/#/R-PFA-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Plasmodium falciparum 4536 R-PFA-8981553 https://reactome.org/PathwayBrowser/#/R-PFA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 4536 R-PFA-8981564 https://reactome.org/PathwayBrowser/#/R-PFA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 4536 R-PFA-8981570 https://reactome.org/PathwayBrowser/#/R-PFA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 4536 R-PFA-8981574 https://reactome.org/PathwayBrowser/#/R-PFA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Plasmodium falciparum 4536 R-RNO-1605591 https://reactome.org/PathwayBrowser/#/R-RNO-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Rattus norvegicus 4536 R-RNO-1606564 https://reactome.org/PathwayBrowser/#/R-RNO-1606564 GALC hydrolyzes GalCer IEA Rattus norvegicus 4536 R-RNO-170810 https://reactome.org/PathwayBrowser/#/R-RNO-170810 nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) IEA Rattus norvegicus 4536 R-RNO-1861788 https://reactome.org/PathwayBrowser/#/R-RNO-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Rattus norvegicus 4536 R-RNO-1861789 https://reactome.org/PathwayBrowser/#/R-RNO-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Rattus norvegicus 4536 R-RNO-188979 https://reactome.org/PathwayBrowser/#/R-RNO-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Rattus norvegicus 4536 R-RNO-189053 https://reactome.org/PathwayBrowser/#/R-RNO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Rattus norvegicus 4536 R-RNO-189062 https://reactome.org/PathwayBrowser/#/R-RNO-189062 lactose + H2O => D-glucose + D-galactose IEA Rattus norvegicus 4536 R-RNO-189069 https://reactome.org/PathwayBrowser/#/R-RNO-189069 sucrose + H2O => glucose + fructose IEA Rattus norvegicus 4536 R-RNO-189208 https://reactome.org/PathwayBrowser/#/R-RNO-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-189242 https://reactome.org/PathwayBrowser/#/R-RNO-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Rattus norvegicus 4536 R-RNO-191101 https://reactome.org/PathwayBrowser/#/R-RNO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 4536 R-RNO-191108 https://reactome.org/PathwayBrowser/#/R-RNO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 4536 R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 4536 R-RNO-265682 https://reactome.org/PathwayBrowser/#/R-RNO-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Rattus norvegicus 4536 R-RNO-3262512 https://reactome.org/PathwayBrowser/#/R-RNO-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Rattus norvegicus 4536 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 4536 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 4536 R-RNO-422048 https://reactome.org/PathwayBrowser/#/R-RNO-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Rattus norvegicus 4536 R-RNO-428779 https://reactome.org/PathwayBrowser/#/R-RNO-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Rattus norvegicus 4536 R-RNO-429036 https://reactome.org/PathwayBrowser/#/R-RNO-429036 SLC2A9 transports Fru, Glc, urate IEA Rattus norvegicus 4536 R-RNO-429094 https://reactome.org/PathwayBrowser/#/R-RNO-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-429567 https://reactome.org/PathwayBrowser/#/R-RNO-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Rattus norvegicus 4536 R-RNO-429613 https://reactome.org/PathwayBrowser/#/R-RNO-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 4536 R-RNO-450095 https://reactome.org/PathwayBrowser/#/R-RNO-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Rattus norvegicus 4536 R-RNO-499981 https://reactome.org/PathwayBrowser/#/R-RNO-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Rattus norvegicus 4536 R-RNO-5339524 https://reactome.org/PathwayBrowser/#/R-RNO-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-5652172 https://reactome.org/PathwayBrowser/#/R-RNO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Rattus norvegicus 4536 R-RNO-5653873 https://reactome.org/PathwayBrowser/#/R-RNO-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Rattus norvegicus 4536 R-RNO-5659861 https://reactome.org/PathwayBrowser/#/R-RNO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 4536 R-RNO-5696021 https://reactome.org/PathwayBrowser/#/R-RNO-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Rattus norvegicus 4536 R-RNO-70420 https://reactome.org/PathwayBrowser/#/R-RNO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Rattus norvegicus 4536 R-RNO-71593 https://reactome.org/PathwayBrowser/#/R-RNO-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Rattus norvegicus 4536 R-RNO-71825 https://reactome.org/PathwayBrowser/#/R-RNO-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Rattus norvegicus 4536 R-RNO-8875902 https://reactome.org/PathwayBrowser/#/R-RNO-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-8876319 https://reactome.org/PathwayBrowser/#/R-RNO-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Rattus norvegicus 4536 R-RNO-8932955 https://reactome.org/PathwayBrowser/#/R-RNO-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-8981553 https://reactome.org/PathwayBrowser/#/R-RNO-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-8981564 https://reactome.org/PathwayBrowser/#/R-RNO-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-8981570 https://reactome.org/PathwayBrowser/#/R-RNO-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-8981574 https://reactome.org/PathwayBrowser/#/R-RNO-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Rattus norvegicus 4536 R-RNO-9036727 https://reactome.org/PathwayBrowser/#/R-RNO-9036727 GAA hydrolyzes lysosomal glycogen IEA Rattus norvegicus 4536 R-RNO-964759 https://reactome.org/PathwayBrowser/#/R-RNO-964759 Alternative endo-mannosidase I route IEA Rattus norvegicus 4536 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 4536 R-SCE-189242 https://reactome.org/PathwayBrowser/#/R-SCE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Saccharomyces cerevisiae 4536 R-SCE-428779 https://reactome.org/PathwayBrowser/#/R-SCE-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Saccharomyces cerevisiae 4536 R-SCE-429036 https://reactome.org/PathwayBrowser/#/R-SCE-429036 SLC2A9 transports Fru, Glc, urate IEA Saccharomyces cerevisiae 4536 R-SCE-450095 https://reactome.org/PathwayBrowser/#/R-SCE-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Saccharomyces cerevisiae 4536 R-SCE-499981 https://reactome.org/PathwayBrowser/#/R-SCE-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Saccharomyces cerevisiae 4536 R-SCE-5339524 https://reactome.org/PathwayBrowser/#/R-SCE-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 4536 R-SCE-5652172 https://reactome.org/PathwayBrowser/#/R-SCE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Saccharomyces cerevisiae 4536 R-SCE-5653873 https://reactome.org/PathwayBrowser/#/R-SCE-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Saccharomyces cerevisiae 4536 R-SCE-70420 https://reactome.org/PathwayBrowser/#/R-SCE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Saccharomyces cerevisiae 4536 R-SCE-71593 https://reactome.org/PathwayBrowser/#/R-SCE-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Saccharomyces cerevisiae 4536 R-SCE-8981553 https://reactome.org/PathwayBrowser/#/R-SCE-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 4536 R-SCE-8981564 https://reactome.org/PathwayBrowser/#/R-SCE-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 4536 R-SCE-8981570 https://reactome.org/PathwayBrowser/#/R-SCE-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 4536 R-SCE-8981574 https://reactome.org/PathwayBrowser/#/R-SCE-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Saccharomyces cerevisiae 4536 R-SPO-189053 https://reactome.org/PathwayBrowser/#/R-SPO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Schizosaccharomyces pombe 4536 R-SPO-189069 https://reactome.org/PathwayBrowser/#/R-SPO-189069 sucrose + H2O => glucose + fructose IEA Schizosaccharomyces pombe 4536 R-SPO-189102 https://reactome.org/PathwayBrowser/#/R-SPO-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 4536 R-SPO-191101 https://reactome.org/PathwayBrowser/#/R-SPO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 4536 R-SPO-191108 https://reactome.org/PathwayBrowser/#/R-SPO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 4536 R-SPO-191116 https://reactome.org/PathwayBrowser/#/R-SPO-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 4536 R-SPO-5652172 https://reactome.org/PathwayBrowser/#/R-SPO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Schizosaccharomyces pombe 4536 R-SPO-5659861 https://reactome.org/PathwayBrowser/#/R-SPO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 4536 R-SPO-70420 https://reactome.org/PathwayBrowser/#/R-SPO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Schizosaccharomyces pombe 4536 R-SPO-8875902 https://reactome.org/PathwayBrowser/#/R-SPO-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Schizosaccharomyces pombe 4536 R-SPO-9036727 https://reactome.org/PathwayBrowser/#/R-SPO-9036727 GAA hydrolyzes lysosomal glycogen IEA Schizosaccharomyces pombe 4536 R-SSC-1605591 https://reactome.org/PathwayBrowser/#/R-SSC-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Sus scrofa 4536 R-SSC-1606564 https://reactome.org/PathwayBrowser/#/R-SSC-1606564 GALC hydrolyzes GalCer IEA Sus scrofa 4536 R-SSC-1861788 https://reactome.org/PathwayBrowser/#/R-SSC-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Sus scrofa 4536 R-SSC-1861789 https://reactome.org/PathwayBrowser/#/R-SSC-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Sus scrofa 4536 R-SSC-188979 https://reactome.org/PathwayBrowser/#/R-SSC-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Sus scrofa 4536 R-SSC-189053 https://reactome.org/PathwayBrowser/#/R-SSC-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Sus scrofa 4536 R-SSC-189062 https://reactome.org/PathwayBrowser/#/R-SSC-189062 lactose + H2O => D-glucose + D-galactose IEA Sus scrofa 4536 R-SSC-189069 https://reactome.org/PathwayBrowser/#/R-SSC-189069 sucrose + H2O => glucose + fructose IEA Sus scrofa 4536 R-SSC-189102 https://reactome.org/PathwayBrowser/#/R-SSC-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Sus scrofa 4536 R-SSC-189208 https://reactome.org/PathwayBrowser/#/R-SSC-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-189242 https://reactome.org/PathwayBrowser/#/R-SSC-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Sus scrofa 4536 R-SSC-191101 https://reactome.org/PathwayBrowser/#/R-SSC-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Sus scrofa 4536 R-SSC-191108 https://reactome.org/PathwayBrowser/#/R-SSC-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 4536 R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 4536 R-SSC-191116 https://reactome.org/PathwayBrowser/#/R-SSC-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Sus scrofa 4536 R-SSC-265682 https://reactome.org/PathwayBrowser/#/R-SSC-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Sus scrofa 4536 R-SSC-3262512 https://reactome.org/PathwayBrowser/#/R-SSC-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Sus scrofa 4536 R-SSC-3266566 https://reactome.org/PathwayBrowser/#/R-SSC-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Sus scrofa 4536 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 4536 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 4536 R-SSC-422048 https://reactome.org/PathwayBrowser/#/R-SSC-422048 Acyl Ghrelin and C-Ghrelin are secreted IEA Sus scrofa 4536 R-SSC-428779 https://reactome.org/PathwayBrowser/#/R-SSC-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Sus scrofa 4536 R-SSC-429036 https://reactome.org/PathwayBrowser/#/R-SSC-429036 SLC2A9 transports Fru, Glc, urate IEA Sus scrofa 4536 R-SSC-429094 https://reactome.org/PathwayBrowser/#/R-SSC-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-429567 https://reactome.org/PathwayBrowser/#/R-SSC-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Sus scrofa 4536 R-SSC-429613 https://reactome.org/PathwayBrowser/#/R-SSC-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 4536 R-SSC-450095 https://reactome.org/PathwayBrowser/#/R-SSC-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Sus scrofa 4536 R-SSC-499981 https://reactome.org/PathwayBrowser/#/R-SSC-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Sus scrofa 4536 R-SSC-5339524 https://reactome.org/PathwayBrowser/#/R-SSC-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-5652172 https://reactome.org/PathwayBrowser/#/R-SSC-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Sus scrofa 4536 R-SSC-5653873 https://reactome.org/PathwayBrowser/#/R-SSC-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Sus scrofa 4536 R-SSC-5653878 https://reactome.org/PathwayBrowser/#/R-SSC-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Sus scrofa 4536 R-SSC-5659861 https://reactome.org/PathwayBrowser/#/R-SSC-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 4536 R-SSC-5696021 https://reactome.org/PathwayBrowser/#/R-SSC-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Sus scrofa 4536 R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa 4536 R-SSC-71593 https://reactome.org/PathwayBrowser/#/R-SSC-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Sus scrofa 4536 R-SSC-71825 https://reactome.org/PathwayBrowser/#/R-SSC-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Sus scrofa 4536 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 4536 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 4536 R-SSC-8875902 https://reactome.org/PathwayBrowser/#/R-SSC-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-8876319 https://reactome.org/PathwayBrowser/#/R-SSC-8876319 SLC50A1 transports Glc from cytosol to extracellular region IEA Sus scrofa 4536 R-SSC-8932955 https://reactome.org/PathwayBrowser/#/R-SSC-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-8981553 https://reactome.org/PathwayBrowser/#/R-SSC-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-8981564 https://reactome.org/PathwayBrowser/#/R-SSC-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-8981570 https://reactome.org/PathwayBrowser/#/R-SSC-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-8981574 https://reactome.org/PathwayBrowser/#/R-SSC-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Sus scrofa 4536 R-SSC-9036727 https://reactome.org/PathwayBrowser/#/R-SSC-9036727 GAA hydrolyzes lysosomal glycogen IEA Sus scrofa 4536 R-SSC-964759 https://reactome.org/PathwayBrowser/#/R-SSC-964759 Alternative endo-mannosidase I route IEA Sus scrofa 4536 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 4536 R-XTR-170810 https://reactome.org/PathwayBrowser/#/R-XTR-170810 nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) IEA Xenopus tropicalis 4536 R-XTR-188979 https://reactome.org/PathwayBrowser/#/R-XTR-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Xenopus tropicalis 4536 R-XTR-189062 https://reactome.org/PathwayBrowser/#/R-XTR-189062 lactose + H2O => D-glucose + D-galactose IEA Xenopus tropicalis 4536 R-XTR-189208 https://reactome.org/PathwayBrowser/#/R-XTR-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-189242 https://reactome.org/PathwayBrowser/#/R-XTR-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Xenopus tropicalis 4536 R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 4536 R-XTR-265682 https://reactome.org/PathwayBrowser/#/R-XTR-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel IEA Xenopus tropicalis 4536 R-XTR-383313 https://reactome.org/PathwayBrowser/#/R-XTR-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Xenopus tropicalis 4536 R-XTR-428779 https://reactome.org/PathwayBrowser/#/R-XTR-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Xenopus tropicalis 4536 R-XTR-429036 https://reactome.org/PathwayBrowser/#/R-XTR-429036 SLC2A9 transports Fru, Glc, urate IEA Xenopus tropicalis 4536 R-XTR-429094 https://reactome.org/PathwayBrowser/#/R-XTR-429094 SLC2A6,8,10,12 transport Glc from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-429613 https://reactome.org/PathwayBrowser/#/R-XTR-429613 SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-450095 https://reactome.org/PathwayBrowser/#/R-XTR-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region IEA Xenopus tropicalis 4536 R-XTR-499981 https://reactome.org/PathwayBrowser/#/R-XTR-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 IEA Xenopus tropicalis 4536 R-XTR-5339524 https://reactome.org/PathwayBrowser/#/R-XTR-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-5652172 https://reactome.org/PathwayBrowser/#/R-XTR-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Xenopus tropicalis 4536 R-XTR-5653873 https://reactome.org/PathwayBrowser/#/R-XTR-5653873 SLC2A1 tetramer transports Glc from cytosol to Golgi lumen IEA Xenopus tropicalis 4536 R-XTR-5653878 https://reactome.org/PathwayBrowser/#/R-XTR-5653878 B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac IEA Xenopus tropicalis 4536 R-XTR-5696021 https://reactome.org/PathwayBrowser/#/R-XTR-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Xenopus tropicalis 4536 R-XTR-70420 https://reactome.org/PathwayBrowser/#/R-XTR-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Xenopus tropicalis 4536 R-XTR-71593 https://reactome.org/PathwayBrowser/#/R-XTR-71593 ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose IEA Xenopus tropicalis 4536 R-XTR-71825 https://reactome.org/PathwayBrowser/#/R-XTR-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Xenopus tropicalis 4536 R-XTR-8875902 https://reactome.org/PathwayBrowser/#/R-XTR-8875902 SLC45A3 transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-8932955 https://reactome.org/PathwayBrowser/#/R-XTR-8932955 SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-8981553 https://reactome.org/PathwayBrowser/#/R-XTR-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-8981564 https://reactome.org/PathwayBrowser/#/R-XTR-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-8981570 https://reactome.org/PathwayBrowser/#/R-XTR-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-8981574 https://reactome.org/PathwayBrowser/#/R-XTR-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol IEA Xenopus tropicalis 4536 R-XTR-964759 https://reactome.org/PathwayBrowser/#/R-XTR-964759 Alternative endo-mannosidase I route IEA Xenopus tropicalis 4538 R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 4538 R-BTA-427555 https://reactome.org/PathwayBrowser/#/R-BTA-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Bos taurus 4538 R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 4538 R-CEL-427555 https://reactome.org/PathwayBrowser/#/R-CEL-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Caenorhabditis elegans 4538 R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 4538 R-CFA-427555 https://reactome.org/PathwayBrowser/#/R-CFA-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Canis familiaris 4538 R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 4538 R-DDI-427555 https://reactome.org/PathwayBrowser/#/R-DDI-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Dictyostelium discoideum 4538 R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 4538 R-DME-427555 https://reactome.org/PathwayBrowser/#/R-DME-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Drosophila melanogaster 4538 R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 4538 R-DRE-427555 https://reactome.org/PathwayBrowser/#/R-DRE-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Danio rerio 4538 R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 4538 R-GGA-427555 https://reactome.org/PathwayBrowser/#/R-GGA-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Gallus gallus 4538 R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 4538 R-HSA-427555 https://reactome.org/PathwayBrowser/#/R-HSA-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol TAS Homo sapiens 4538 R-HSA-9640316 https://reactome.org/PathwayBrowser/#/R-HSA-9640316 DeHA hydrolyses to threonate and oxalate TAS Homo sapiens 4538 R-HSA-9640321 https://reactome.org/PathwayBrowser/#/R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate TAS Homo sapiens 4538 R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 4538 R-MMU-427555 https://reactome.org/PathwayBrowser/#/R-MMU-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Mus musculus 4538 R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 4538 R-RNO-427555 https://reactome.org/PathwayBrowser/#/R-RNO-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Rattus norvegicus 4538 R-SCE-427555 https://reactome.org/PathwayBrowser/#/R-SCE-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Saccharomyces cerevisiae 4538 R-SPO-427555 https://reactome.org/PathwayBrowser/#/R-SPO-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Schizosaccharomyces pombe 4538 R-SSC-389862 https://reactome.org/PathwayBrowser/#/R-SSC-389862 Conversion of glyoxylate to oxalate IEA Sus scrofa 4538 R-SSC-427555 https://reactome.org/PathwayBrowser/#/R-SSC-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Sus scrofa 4538 R-XTR-389862 https://reactome.org/PathwayBrowser/#/R-XTR-389862 Conversion of glyoxylate to oxalate IEA Xenopus tropicalis 4538 R-XTR-427555 https://reactome.org/PathwayBrowser/#/R-XTR-427555 SLC26A1,2 cotransport SO4(2-), anion from extracellular region to cytosol IEA Xenopus tropicalis 4539 R-BTA-350604 https://reactome.org/PathwayBrowser/#/R-BTA-350604 Agmatine + H2O <=> putrescine + urea IEA Bos taurus 4539 R-BTA-444126 https://reactome.org/PathwayBrowser/#/R-BTA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Bos taurus 4539 R-BTA-452036 https://reactome.org/PathwayBrowser/#/R-BTA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Bos taurus 4539 R-BTA-507873 https://reactome.org/PathwayBrowser/#/R-BTA-507873 Aquaporins passively transport urea out of cells IEA Bos taurus 4539 R-BTA-507875 https://reactome.org/PathwayBrowser/#/R-BTA-507875 Aquaporins passively transport urea into cells IEA Bos taurus 4539 R-BTA-70569 https://reactome.org/PathwayBrowser/#/R-BTA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Bos taurus 4539 R-CEL-452036 https://reactome.org/PathwayBrowser/#/R-CEL-452036 arginine + H2O => ornithine + urea [ARG2] IEA Caenorhabditis elegans 4539 R-CEL-507873 https://reactome.org/PathwayBrowser/#/R-CEL-507873 Aquaporins passively transport urea out of cells IEA Caenorhabditis elegans 4539 R-CEL-507875 https://reactome.org/PathwayBrowser/#/R-CEL-507875 Aquaporins passively transport urea into cells IEA Caenorhabditis elegans 4539 R-CEL-70569 https://reactome.org/PathwayBrowser/#/R-CEL-70569 arginine + H2O => ornithine + urea [ARG1] IEA Caenorhabditis elegans 4539 R-CFA-350604 https://reactome.org/PathwayBrowser/#/R-CFA-350604 Agmatine + H2O <=> putrescine + urea IEA Canis familiaris 4539 R-CFA-444126 https://reactome.org/PathwayBrowser/#/R-CFA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Canis familiaris 4539 R-CFA-452036 https://reactome.org/PathwayBrowser/#/R-CFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Canis familiaris 4539 R-CFA-507873 https://reactome.org/PathwayBrowser/#/R-CFA-507873 Aquaporins passively transport urea out of cells IEA Canis familiaris 4539 R-CFA-507875 https://reactome.org/PathwayBrowser/#/R-CFA-507875 Aquaporins passively transport urea into cells IEA Canis familiaris 4539 R-CFA-70569 https://reactome.org/PathwayBrowser/#/R-CFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Canis familiaris 4539 R-DDI-444126 https://reactome.org/PathwayBrowser/#/R-DDI-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Dictyostelium discoideum 4539 R-DDI-452036 https://reactome.org/PathwayBrowser/#/R-DDI-452036 arginine + H2O => ornithine + urea [ARG2] IEA Dictyostelium discoideum 4539 R-DDI-70569 https://reactome.org/PathwayBrowser/#/R-DDI-70569 arginine + H2O => ornithine + urea [ARG1] IEA Dictyostelium discoideum 4539 R-DME-452036 https://reactome.org/PathwayBrowser/#/R-DME-452036 arginine + H2O => ornithine + urea [ARG2] IEA Drosophila melanogaster 4539 R-DME-70569 https://reactome.org/PathwayBrowser/#/R-DME-70569 arginine + H2O => ornithine + urea [ARG1] IEA Drosophila melanogaster 4539 R-DRE-350604 https://reactome.org/PathwayBrowser/#/R-DRE-350604 Agmatine + H2O <=> putrescine + urea IEA Danio rerio 4539 R-DRE-444126 https://reactome.org/PathwayBrowser/#/R-DRE-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Danio rerio 4539 R-DRE-452036 https://reactome.org/PathwayBrowser/#/R-DRE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Danio rerio 4539 R-DRE-507873 https://reactome.org/PathwayBrowser/#/R-DRE-507873 Aquaporins passively transport urea out of cells IEA Danio rerio 4539 R-DRE-507875 https://reactome.org/PathwayBrowser/#/R-DRE-507875 Aquaporins passively transport urea into cells IEA Danio rerio 4539 R-GGA-187632 https://reactome.org/PathwayBrowser/#/R-GGA-187632 arginine + H2O => ornithine + urea TAS Gallus gallus 4539 R-GGA-350604 https://reactome.org/PathwayBrowser/#/R-GGA-350604 Agmatine + H2O <=> putrescine + urea IEA Gallus gallus 4539 R-GGA-444126 https://reactome.org/PathwayBrowser/#/R-GGA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Gallus gallus 4539 R-GGA-452036 https://reactome.org/PathwayBrowser/#/R-GGA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Gallus gallus 4539 R-GGA-507873 https://reactome.org/PathwayBrowser/#/R-GGA-507873 Aquaporins passively transport urea out of cells IEA Gallus gallus 4539 R-GGA-507875 https://reactome.org/PathwayBrowser/#/R-GGA-507875 Aquaporins passively transport urea into cells IEA Gallus gallus 4539 R-HSA-350604 https://reactome.org/PathwayBrowser/#/R-HSA-350604 Agmatine + H2O <=> putrescine + urea TAS Homo sapiens 4539 R-HSA-444126 https://reactome.org/PathwayBrowser/#/R-HSA-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively TAS Homo sapiens 4539 R-HSA-452036 https://reactome.org/PathwayBrowser/#/R-HSA-452036 arginine + H2O => ornithine + urea [ARG2] TAS Homo sapiens 4539 R-HSA-507873 https://reactome.org/PathwayBrowser/#/R-HSA-507873 Aquaporins passively transport urea out of cells TAS Homo sapiens 4539 R-HSA-507875 https://reactome.org/PathwayBrowser/#/R-HSA-507875 Aquaporins passively transport urea into cells TAS Homo sapiens 4539 R-HSA-70569 https://reactome.org/PathwayBrowser/#/R-HSA-70569 arginine + H2O => ornithine + urea [ARG1] TAS Homo sapiens 4539 R-MMU-350604 https://reactome.org/PathwayBrowser/#/R-MMU-350604 Agmatine + H2O <=> putrescine + urea IEA Mus musculus 4539 R-MMU-444126 https://reactome.org/PathwayBrowser/#/R-MMU-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Mus musculus 4539 R-MMU-452036 https://reactome.org/PathwayBrowser/#/R-MMU-452036 arginine + H2O => ornithine + urea [ARG2] IEA Mus musculus 4539 R-MMU-507873 https://reactome.org/PathwayBrowser/#/R-MMU-507873 Aquaporins passively transport urea out of cells IEA Mus musculus 4539 R-MMU-507875 https://reactome.org/PathwayBrowser/#/R-MMU-507875 Aquaporins passively transport urea into cells IEA Mus musculus 4539 R-MMU-70569 https://reactome.org/PathwayBrowser/#/R-MMU-70569 arginine + H2O => ornithine + urea [ARG1] IEA Mus musculus 4539 R-PFA-452036 https://reactome.org/PathwayBrowser/#/R-PFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Plasmodium falciparum 4539 R-PFA-507873 https://reactome.org/PathwayBrowser/#/R-PFA-507873 Aquaporins passively transport urea out of cells IEA Plasmodium falciparum 4539 R-PFA-507875 https://reactome.org/PathwayBrowser/#/R-PFA-507875 Aquaporins passively transport urea into cells IEA Plasmodium falciparum 4539 R-PFA-70569 https://reactome.org/PathwayBrowser/#/R-PFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Plasmodium falciparum 4539 R-RNO-350604 https://reactome.org/PathwayBrowser/#/R-RNO-350604 Agmatine + H2O <=> putrescine + urea IEA Rattus norvegicus 4539 R-RNO-444126 https://reactome.org/PathwayBrowser/#/R-RNO-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Rattus norvegicus 4539 R-RNO-452036 https://reactome.org/PathwayBrowser/#/R-RNO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Rattus norvegicus 4539 R-RNO-507873 https://reactome.org/PathwayBrowser/#/R-RNO-507873 Aquaporins passively transport urea out of cells IEA Rattus norvegicus 4539 R-RNO-507875 https://reactome.org/PathwayBrowser/#/R-RNO-507875 Aquaporins passively transport urea into cells IEA Rattus norvegicus 4539 R-RNO-70569 https://reactome.org/PathwayBrowser/#/R-RNO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Rattus norvegicus 4539 R-SCE-452036 https://reactome.org/PathwayBrowser/#/R-SCE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Saccharomyces cerevisiae 4539 R-SCE-507873 https://reactome.org/PathwayBrowser/#/R-SCE-507873 Aquaporins passively transport urea out of cells IEA Saccharomyces cerevisiae 4539 R-SCE-507875 https://reactome.org/PathwayBrowser/#/R-SCE-507875 Aquaporins passively transport urea into cells IEA Saccharomyces cerevisiae 4539 R-SCE-70569 https://reactome.org/PathwayBrowser/#/R-SCE-70569 arginine + H2O => ornithine + urea [ARG1] IEA Saccharomyces cerevisiae 4539 R-SPO-452036 https://reactome.org/PathwayBrowser/#/R-SPO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Schizosaccharomyces pombe 4539 R-SPO-507873 https://reactome.org/PathwayBrowser/#/R-SPO-507873 Aquaporins passively transport urea out of cells IEA Schizosaccharomyces pombe 4539 R-SPO-507875 https://reactome.org/PathwayBrowser/#/R-SPO-507875 Aquaporins passively transport urea into cells IEA Schizosaccharomyces pombe 4539 R-SPO-70569 https://reactome.org/PathwayBrowser/#/R-SPO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Schizosaccharomyces pombe 4539 R-SSC-350604 https://reactome.org/PathwayBrowser/#/R-SSC-350604 Agmatine + H2O <=> putrescine + urea IEA Sus scrofa 4539 R-SSC-444126 https://reactome.org/PathwayBrowser/#/R-SSC-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Sus scrofa 4539 R-SSC-452036 https://reactome.org/PathwayBrowser/#/R-SSC-452036 arginine + H2O => ornithine + urea [ARG2] IEA Sus scrofa 4539 R-SSC-507873 https://reactome.org/PathwayBrowser/#/R-SSC-507873 Aquaporins passively transport urea out of cells IEA Sus scrofa 4539 R-SSC-507875 https://reactome.org/PathwayBrowser/#/R-SSC-507875 Aquaporins passively transport urea into cells IEA Sus scrofa 4539 R-SSC-70569 https://reactome.org/PathwayBrowser/#/R-SSC-70569 arginine + H2O => ornithine + urea [ARG1] IEA Sus scrofa 4539 R-XTR-350604 https://reactome.org/PathwayBrowser/#/R-XTR-350604 Agmatine + H2O <=> putrescine + urea IEA Xenopus tropicalis 4539 R-XTR-444126 https://reactome.org/PathwayBrowser/#/R-XTR-444126 HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively IEA Xenopus tropicalis 4539 R-XTR-452036 https://reactome.org/PathwayBrowser/#/R-XTR-452036 arginine + H2O => ornithine + urea [ARG2] IEA Xenopus tropicalis 4539 R-XTR-507873 https://reactome.org/PathwayBrowser/#/R-XTR-507873 Aquaporins passively transport urea out of cells IEA Xenopus tropicalis 4539 R-XTR-507875 https://reactome.org/PathwayBrowser/#/R-XTR-507875 Aquaporins passively transport urea into cells IEA Xenopus tropicalis 4539 R-XTR-70569 https://reactome.org/PathwayBrowser/#/R-XTR-70569 arginine + H2O => ornithine + urea [ARG1] IEA Xenopus tropicalis 4551 R-BTA-1483004 https://reactome.org/PathwayBrowser/#/R-BTA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Bos taurus 4551 R-BTA-1483159 https://reactome.org/PathwayBrowser/#/R-BTA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Bos taurus 4551 R-BTA-1483182 https://reactome.org/PathwayBrowser/#/R-BTA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Bos taurus 4551 R-BTA-1483186 https://reactome.org/PathwayBrowser/#/R-BTA-1483186 PC is converted to PS by PTDSS1 IEA Bos taurus 4551 R-BTA-2029471 https://reactome.org/PathwayBrowser/#/R-BTA-2029471 Hydrolysis of PC to PA by PLD IEA Bos taurus 4551 R-BTA-264622 https://reactome.org/PathwayBrowser/#/R-BTA-264622 Cho is acetylated to AcCho by CHAT IEA Bos taurus 4551 R-BTA-429594 https://reactome.org/PathwayBrowser/#/R-BTA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 4551 R-BTA-444433 https://reactome.org/PathwayBrowser/#/R-BTA-444433 Cho transports from the extracellular space to the cytosol IEA Bos taurus 4551 R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 4551 R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 4551 R-BTA-6797956 https://reactome.org/PathwayBrowser/#/R-BTA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Bos taurus 4551 R-BTA-6797961 https://reactome.org/PathwayBrowser/#/R-BTA-6797961 CHDH oxidises Cho to BETALD IEA Bos taurus 4551 R-CEL-1483004 https://reactome.org/PathwayBrowser/#/R-CEL-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Caenorhabditis elegans 4551 R-CEL-1483182 https://reactome.org/PathwayBrowser/#/R-CEL-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Caenorhabditis elegans 4551 R-CEL-1483186 https://reactome.org/PathwayBrowser/#/R-CEL-1483186 PC is converted to PS by PTDSS1 IEA Caenorhabditis elegans 4551 R-CEL-2029471 https://reactome.org/PathwayBrowser/#/R-CEL-2029471 Hydrolysis of PC to PA by PLD IEA Caenorhabditis elegans 4551 R-CEL-264622 https://reactome.org/PathwayBrowser/#/R-CEL-264622 Cho is acetylated to AcCho by CHAT IEA Caenorhabditis elegans 4551 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 4551 R-CEL-429594 https://reactome.org/PathwayBrowser/#/R-CEL-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 4551 R-CEL-444433 https://reactome.org/PathwayBrowser/#/R-CEL-444433 Cho transports from the extracellular space to the cytosol IEA Caenorhabditis elegans 4551 R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 4551 R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 4551 R-CEL-6797961 https://reactome.org/PathwayBrowser/#/R-CEL-6797961 CHDH oxidises Cho to BETALD IEA Caenorhabditis elegans 4551 R-CFA-1483004 https://reactome.org/PathwayBrowser/#/R-CFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Canis familiaris 4551 R-CFA-1483159 https://reactome.org/PathwayBrowser/#/R-CFA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Canis familiaris 4551 R-CFA-1483182 https://reactome.org/PathwayBrowser/#/R-CFA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Canis familiaris 4551 R-CFA-1483186 https://reactome.org/PathwayBrowser/#/R-CFA-1483186 PC is converted to PS by PTDSS1 IEA Canis familiaris 4551 R-CFA-2029471 https://reactome.org/PathwayBrowser/#/R-CFA-2029471 Hydrolysis of PC to PA by PLD IEA Canis familiaris 4551 R-CFA-264622 https://reactome.org/PathwayBrowser/#/R-CFA-264622 Cho is acetylated to AcCho by CHAT IEA Canis familiaris 4551 R-CFA-429594 https://reactome.org/PathwayBrowser/#/R-CFA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 4551 R-CFA-444433 https://reactome.org/PathwayBrowser/#/R-CFA-444433 Cho transports from the extracellular space to the cytosol IEA Canis familiaris 4551 R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 4551 R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 4551 R-CFA-6797956 https://reactome.org/PathwayBrowser/#/R-CFA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Canis familiaris 4551 R-CFA-6797961 https://reactome.org/PathwayBrowser/#/R-CFA-6797961 CHDH oxidises Cho to BETALD IEA Canis familiaris 4551 R-DDI-1483182 https://reactome.org/PathwayBrowser/#/R-DDI-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Dictyostelium discoideum 4551 R-DDI-1483186 https://reactome.org/PathwayBrowser/#/R-DDI-1483186 PC is converted to PS by PTDSS1 IEA Dictyostelium discoideum 4551 R-DDI-2029471 https://reactome.org/PathwayBrowser/#/R-DDI-2029471 Hydrolysis of PC to PA by PLD IEA Dictyostelium discoideum 4551 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 4551 R-DDI-444433 https://reactome.org/PathwayBrowser/#/R-DDI-444433 Cho transports from the extracellular space to the cytosol IEA Dictyostelium discoideum 4551 R-DDI-6797956 https://reactome.org/PathwayBrowser/#/R-DDI-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 4551 R-DDI-6797961 https://reactome.org/PathwayBrowser/#/R-DDI-6797961 CHDH oxidises Cho to BETALD IEA Dictyostelium discoideum 4551 R-DME-1483004 https://reactome.org/PathwayBrowser/#/R-DME-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Drosophila melanogaster 4551 R-DME-1483159 https://reactome.org/PathwayBrowser/#/R-DME-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Drosophila melanogaster 4551 R-DME-1483182 https://reactome.org/PathwayBrowser/#/R-DME-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Drosophila melanogaster 4551 R-DME-1483186 https://reactome.org/PathwayBrowser/#/R-DME-1483186 PC is converted to PS by PTDSS1 IEA Drosophila melanogaster 4551 R-DME-2029471 https://reactome.org/PathwayBrowser/#/R-DME-2029471 Hydrolysis of PC to PA by PLD IEA Drosophila melanogaster 4551 R-DME-264622 https://reactome.org/PathwayBrowser/#/R-DME-264622 Cho is acetylated to AcCho by CHAT IEA Drosophila melanogaster 4551 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 4551 R-DME-429594 https://reactome.org/PathwayBrowser/#/R-DME-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 4551 R-DME-444433 https://reactome.org/PathwayBrowser/#/R-DME-444433 Cho transports from the extracellular space to the cytosol IEA Drosophila melanogaster 4551 R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 4551 R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 4551 R-DME-6797956 https://reactome.org/PathwayBrowser/#/R-DME-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Drosophila melanogaster 4551 R-DME-6797961 https://reactome.org/PathwayBrowser/#/R-DME-6797961 CHDH oxidises Cho to BETALD IEA Drosophila melanogaster 4551 R-DRE-1483004 https://reactome.org/PathwayBrowser/#/R-DRE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Danio rerio 4551 R-DRE-1483159 https://reactome.org/PathwayBrowser/#/R-DRE-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Danio rerio 4551 R-DRE-1483186 https://reactome.org/PathwayBrowser/#/R-DRE-1483186 PC is converted to PS by PTDSS1 IEA Danio rerio 4551 R-DRE-264622 https://reactome.org/PathwayBrowser/#/R-DRE-264622 Cho is acetylated to AcCho by CHAT IEA Danio rerio 4551 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 4551 R-DRE-444433 https://reactome.org/PathwayBrowser/#/R-DRE-444433 Cho transports from the extracellular space to the cytosol IEA Danio rerio 4551 R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 4551 R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 4551 R-GGA-1483004 https://reactome.org/PathwayBrowser/#/R-GGA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Gallus gallus 4551 R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus 4551 R-GGA-1483182 https://reactome.org/PathwayBrowser/#/R-GGA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Gallus gallus 4551 R-GGA-1483186 https://reactome.org/PathwayBrowser/#/R-GGA-1483186 PC is converted to PS by PTDSS1 IEA Gallus gallus 4551 R-GGA-264622 https://reactome.org/PathwayBrowser/#/R-GGA-264622 Cho is acetylated to AcCho by CHAT IEA Gallus gallus 4551 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 4551 R-GGA-429594 https://reactome.org/PathwayBrowser/#/R-GGA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 4551 R-GGA-444433 https://reactome.org/PathwayBrowser/#/R-GGA-444433 Cho transports from the extracellular space to the cytosol IEA Gallus gallus 4551 R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 4551 R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 4551 R-GGA-6797956 https://reactome.org/PathwayBrowser/#/R-GGA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Gallus gallus 4551 R-GGA-6797961 https://reactome.org/PathwayBrowser/#/R-GGA-6797961 CHDH oxidises Cho to BETALD IEA Gallus gallus 4551 R-HSA-1483004 https://reactome.org/PathwayBrowser/#/R-HSA-1483004 Cho is phosphorylated to PCho by CHK dimer TAS Homo sapiens 4551 R-HSA-1483116 https://reactome.org/PathwayBrowser/#/R-HSA-1483116 GPCho is hydrolyzed to Cho and G3P by GPCPD1 IEA Homo sapiens 4551 R-HSA-1483142 https://reactome.org/PathwayBrowser/#/R-HSA-1483142 PC is transphosphatidylated to PG by PLD1-4/6 IEA Homo sapiens 4551 R-HSA-1483159 https://reactome.org/PathwayBrowser/#/R-HSA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 TAS Homo sapiens 4551 R-HSA-1483182 https://reactome.org/PathwayBrowser/#/R-HSA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 TAS Homo sapiens 4551 R-HSA-1483186 https://reactome.org/PathwayBrowser/#/R-HSA-1483186 PC is converted to PS by PTDSS1 TAS Homo sapiens 4551 R-HSA-2029471 https://reactome.org/PathwayBrowser/#/R-HSA-2029471 Hydrolysis of PC to PA by PLD TAS Homo sapiens 4551 R-HSA-264622 https://reactome.org/PathwayBrowser/#/R-HSA-264622 Cho is acetylated to AcCho by CHAT TAS Homo sapiens 4551 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 4551 R-HSA-429594 https://reactome.org/PathwayBrowser/#/R-HSA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 4551 R-HSA-444433 https://reactome.org/PathwayBrowser/#/R-HSA-444433 Cho transports from the extracellular space to the cytosol TAS Homo sapiens 4551 R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 4551 R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 4551 R-HSA-5658483 https://reactome.org/PathwayBrowser/#/R-HSA-5658483 Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 4551 R-HSA-6797956 https://reactome.org/PathwayBrowser/#/R-HSA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix TAS Homo sapiens 4551 R-HSA-6797961 https://reactome.org/PathwayBrowser/#/R-HSA-6797961 CHDH oxidises Cho to BETALD TAS Homo sapiens 4551 R-HSA-6814132 https://reactome.org/PathwayBrowser/#/R-HSA-6814132 GDPD5 hydrolyzes GPCho IEA Homo sapiens 4551 R-MMU-1483004 https://reactome.org/PathwayBrowser/#/R-MMU-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Mus musculus 4551 R-MMU-1483112 https://reactome.org/PathwayBrowser/#/R-MMU-1483112 GPCho is hydrolyzed to Cho and G3P by Gpcpd1 TAS Mus musculus 4551 R-MMU-1483159 https://reactome.org/PathwayBrowser/#/R-MMU-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Mus musculus 4551 R-MMU-1483172 https://reactome.org/PathwayBrowser/#/R-MMU-1483172 PC is transphosphatidylated to PG by Pld1-4/6 TAS Mus musculus 4551 R-MMU-1483182 https://reactome.org/PathwayBrowser/#/R-MMU-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Mus musculus 4551 R-MMU-1483186 https://reactome.org/PathwayBrowser/#/R-MMU-1483186 PC is converted to PS by PTDSS1 IEA Mus musculus 4551 R-MMU-2029471 https://reactome.org/PathwayBrowser/#/R-MMU-2029471 Hydrolysis of PC to PA by PLD IEA Mus musculus 4551 R-MMU-264622 https://reactome.org/PathwayBrowser/#/R-MMU-264622 Cho is acetylated to AcCho by CHAT IEA Mus musculus 4551 R-MMU-429594 https://reactome.org/PathwayBrowser/#/R-MMU-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 4551 R-MMU-444433 https://reactome.org/PathwayBrowser/#/R-MMU-444433 Cho transports from the extracellular space to the cytosol IEA Mus musculus 4551 R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 4551 R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 4551 R-MMU-6797956 https://reactome.org/PathwayBrowser/#/R-MMU-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Mus musculus 4551 R-MMU-6797961 https://reactome.org/PathwayBrowser/#/R-MMU-6797961 CHDH oxidises Cho to BETALD IEA Mus musculus 4551 R-MMU-6814137 https://reactome.org/PathwayBrowser/#/R-MMU-6814137 Gdpd5 hydrolyzes GPCho TAS Mus musculus 4551 R-PFA-1483004 https://reactome.org/PathwayBrowser/#/R-PFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Plasmodium falciparum 4551 R-PFA-1483186 https://reactome.org/PathwayBrowser/#/R-PFA-1483186 PC is converted to PS by PTDSS1 IEA Plasmodium falciparum 4551 R-PFA-444433 https://reactome.org/PathwayBrowser/#/R-PFA-444433 Cho transports from the extracellular space to the cytosol IEA Plasmodium falciparum 4551 R-PFA-6797956 https://reactome.org/PathwayBrowser/#/R-PFA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Plasmodium falciparum 4551 R-RNO-1483004 https://reactome.org/PathwayBrowser/#/R-RNO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Rattus norvegicus 4551 R-RNO-1483159 https://reactome.org/PathwayBrowser/#/R-RNO-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Rattus norvegicus 4551 R-RNO-1483182 https://reactome.org/PathwayBrowser/#/R-RNO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Rattus norvegicus 4551 R-RNO-1483186 https://reactome.org/PathwayBrowser/#/R-RNO-1483186 PC is converted to PS by PTDSS1 IEA Rattus norvegicus 4551 R-RNO-2029471 https://reactome.org/PathwayBrowser/#/R-RNO-2029471 Hydrolysis of PC to PA by PLD IEA Rattus norvegicus 4551 R-RNO-264622 https://reactome.org/PathwayBrowser/#/R-RNO-264622 Cho is acetylated to AcCho by CHAT IEA Rattus norvegicus 4551 R-RNO-429594 https://reactome.org/PathwayBrowser/#/R-RNO-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 4551 R-RNO-444433 https://reactome.org/PathwayBrowser/#/R-RNO-444433 Cho transports from the extracellular space to the cytosol IEA Rattus norvegicus 4551 R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 4551 R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 4551 R-RNO-6797956 https://reactome.org/PathwayBrowser/#/R-RNO-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Rattus norvegicus 4551 R-RNO-6797961 https://reactome.org/PathwayBrowser/#/R-RNO-6797961 CHDH oxidises Cho to BETALD IEA Rattus norvegicus 4551 R-SCE-1483004 https://reactome.org/PathwayBrowser/#/R-SCE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Saccharomyces cerevisiae 4551 R-SCE-1483182 https://reactome.org/PathwayBrowser/#/R-SCE-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Saccharomyces cerevisiae 4551 R-SCE-2029471 https://reactome.org/PathwayBrowser/#/R-SCE-2029471 Hydrolysis of PC to PA by PLD IEA Saccharomyces cerevisiae 4551 R-SPO-1483004 https://reactome.org/PathwayBrowser/#/R-SPO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Schizosaccharomyces pombe 4551 R-SPO-1483182 https://reactome.org/PathwayBrowser/#/R-SPO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Schizosaccharomyces pombe 4551 R-SPO-2029471 https://reactome.org/PathwayBrowser/#/R-SPO-2029471 Hydrolysis of PC to PA by PLD IEA Schizosaccharomyces pombe 4551 R-SSC-1483004 https://reactome.org/PathwayBrowser/#/R-SSC-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Sus scrofa 4551 R-SSC-1483159 https://reactome.org/PathwayBrowser/#/R-SSC-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Sus scrofa 4551 R-SSC-1483182 https://reactome.org/PathwayBrowser/#/R-SSC-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Sus scrofa 4551 R-SSC-1483186 https://reactome.org/PathwayBrowser/#/R-SSC-1483186 PC is converted to PS by PTDSS1 IEA Sus scrofa 4551 R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa 4551 R-SSC-264622 https://reactome.org/PathwayBrowser/#/R-SSC-264622 Cho is acetylated to AcCho by CHAT IEA Sus scrofa 4551 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 4551 R-SSC-429594 https://reactome.org/PathwayBrowser/#/R-SSC-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 4551 R-SSC-444433 https://reactome.org/PathwayBrowser/#/R-SSC-444433 Cho transports from the extracellular space to the cytosol IEA Sus scrofa 4551 R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 4551 R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 4551 R-SSC-6797956 https://reactome.org/PathwayBrowser/#/R-SSC-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Sus scrofa 4551 R-SSC-6797961 https://reactome.org/PathwayBrowser/#/R-SSC-6797961 CHDH oxidises Cho to BETALD IEA Sus scrofa 4551 R-XTR-1483004 https://reactome.org/PathwayBrowser/#/R-XTR-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Xenopus tropicalis 4551 R-XTR-1483159 https://reactome.org/PathwayBrowser/#/R-XTR-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Xenopus tropicalis 4551 R-XTR-1483182 https://reactome.org/PathwayBrowser/#/R-XTR-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Xenopus tropicalis 4551 R-XTR-1483186 https://reactome.org/PathwayBrowser/#/R-XTR-1483186 PC is converted to PS by PTDSS1 IEA Xenopus tropicalis 4551 R-XTR-2029471 https://reactome.org/PathwayBrowser/#/R-XTR-2029471 Hydrolysis of PC to PA by PLD IEA Xenopus tropicalis 4551 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 4551 R-XTR-429594 https://reactome.org/PathwayBrowser/#/R-XTR-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 4551 R-XTR-444433 https://reactome.org/PathwayBrowser/#/R-XTR-444433 Cho transports from the extracellular space to the cytosol IEA Xenopus tropicalis 4551 R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 4551 R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 4551 R-XTR-6797956 https://reactome.org/PathwayBrowser/#/R-XTR-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Xenopus tropicalis 4554 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 4554 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 4554 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 4554 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4554 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4554 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4554 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4554 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 4554 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 4554 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 4554 R-BTA-2162066 https://reactome.org/PathwayBrowser/#/R-BTA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Bos taurus 4554 R-BTA-5693346 https://reactome.org/PathwayBrowser/#/R-BTA-5693346 CECRI deaminates Ade-Rib to Ino IEA Bos taurus 4554 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 4554 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 4554 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 4554 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 4554 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 4554 R-BTA-9754916 https://reactome.org/PathwayBrowser/#/R-BTA-9754916 NT5C2 tetramer phosphorylates RBV IEA Bos taurus 4554 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4554 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4554 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4554 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4554 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 4554 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 4554 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 4554 R-CEL-2162066 https://reactome.org/PathwayBrowser/#/R-CEL-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Caenorhabditis elegans 4554 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 4554 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 4554 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 4554 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 4554 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 4554 R-CEL-9754916 https://reactome.org/PathwayBrowser/#/R-CEL-9754916 NT5C2 tetramer phosphorylates RBV IEA Caenorhabditis elegans 4554 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 4554 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 4554 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 4554 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4554 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4554 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4554 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4554 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 4554 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 4554 R-CFA-2162066 https://reactome.org/PathwayBrowser/#/R-CFA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Canis familiaris 4554 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 4554 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 4554 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 4554 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 4554 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 4554 R-CFA-9754916 https://reactome.org/PathwayBrowser/#/R-CFA-9754916 NT5C2 tetramer phosphorylates RBV IEA Canis familiaris 4554 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4554 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4554 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4554 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4554 R-DDI-2162066 https://reactome.org/PathwayBrowser/#/R-DDI-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Dictyostelium discoideum 4554 R-DDI-5693346 https://reactome.org/PathwayBrowser/#/R-DDI-5693346 CECRI deaminates Ade-Rib to Ino IEA Dictyostelium discoideum 4554 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 4554 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 4554 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 4554 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 4554 R-DDI-9754916 https://reactome.org/PathwayBrowser/#/R-DDI-9754916 NT5C2 tetramer phosphorylates RBV IEA Dictyostelium discoideum 4554 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 4554 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4554 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4554 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4554 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4554 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 4554 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 4554 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 4554 R-DME-2162066 https://reactome.org/PathwayBrowser/#/R-DME-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Drosophila melanogaster 4554 R-DME-5693346 https://reactome.org/PathwayBrowser/#/R-DME-5693346 CECRI deaminates Ade-Rib to Ino IEA Drosophila melanogaster 4554 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 4554 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 4554 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 4554 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 4554 R-DME-9754916 https://reactome.org/PathwayBrowser/#/R-DME-9754916 NT5C2 tetramer phosphorylates RBV IEA Drosophila melanogaster 4554 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 4554 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 4554 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4554 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4554 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 4554 R-DRE-5693346 https://reactome.org/PathwayBrowser/#/R-DRE-5693346 CECRI deaminates Ade-Rib to Ino IEA Danio rerio 4554 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 4554 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 4554 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 4554 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 4554 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 4554 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 4554 R-GGA-2162066 https://reactome.org/PathwayBrowser/#/R-GGA-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Gallus gallus 4554 R-GGA-421174 https://reactome.org/PathwayBrowser/#/R-GGA-421174 inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate IEA Gallus gallus 4554 R-GGA-421179 https://reactome.org/PathwayBrowser/#/R-GGA-421179 inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate IEA Gallus gallus 4554 R-GGA-5693346 https://reactome.org/PathwayBrowser/#/R-GGA-5693346 CECRI deaminates Ade-Rib to Ino IEA Gallus gallus 4554 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 4554 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 4554 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 4554 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 4554 R-GGA-9754916 https://reactome.org/PathwayBrowser/#/R-GGA-9754916 NT5C2 tetramer phosphorylates RBV IEA Gallus gallus 4554 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 4554 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 4554 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 4554 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4554 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4554 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4554 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4554 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 4554 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 4554 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 4554 R-HSA-2162066 https://reactome.org/PathwayBrowser/#/R-HSA-2162066 carbovir + IMP => carbovir monophosphate + inosine TAS Homo sapiens 4554 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4554 R-HSA-5693346 https://reactome.org/PathwayBrowser/#/R-HSA-5693346 CECRI deaminates Ade-Rib to Ino TAS Homo sapiens 4554 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4554 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 4554 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 4554 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 4554 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 4554 R-HSA-9735775 https://reactome.org/PathwayBrowser/#/R-HSA-9735775 Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 4554 R-HSA-9754916 https://reactome.org/PathwayBrowser/#/R-HSA-9754916 NT5C2 tetramer phosphorylates RBV TAS Homo sapiens 4554 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 4554 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 4554 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 4554 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4554 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4554 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4554 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4554 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 4554 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 4554 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 4554 R-MMU-2162066 https://reactome.org/PathwayBrowser/#/R-MMU-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Mus musculus 4554 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 4554 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 4554 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 4554 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 4554 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 4554 R-MMU-9754916 https://reactome.org/PathwayBrowser/#/R-MMU-9754916 NT5C2 tetramer phosphorylates RBV IEA Mus musculus 4554 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4554 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4554 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4554 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4554 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 4554 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 4554 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 4554 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 4554 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 4554 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 4554 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4554 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4554 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4554 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4554 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 4554 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 4554 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 4554 R-RNO-2162066 https://reactome.org/PathwayBrowser/#/R-RNO-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Rattus norvegicus 4554 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 4554 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 4554 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 4554 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 4554 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 4554 R-RNO-9754916 https://reactome.org/PathwayBrowser/#/R-RNO-9754916 NT5C2 tetramer phosphorylates RBV IEA Rattus norvegicus 4554 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 4554 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 4554 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 4554 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 4554 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 4554 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 4554 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 4554 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4554 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4554 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4554 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4554 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 4554 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 4554 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 4554 R-SSC-2162066 https://reactome.org/PathwayBrowser/#/R-SSC-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Sus scrofa 4554 R-SSC-5693346 https://reactome.org/PathwayBrowser/#/R-SSC-5693346 CECRI deaminates Ade-Rib to Ino IEA Sus scrofa 4554 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 4554 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 4554 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 4554 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 4554 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 4554 R-SSC-9754916 https://reactome.org/PathwayBrowser/#/R-SSC-9754916 NT5C2 tetramer phosphorylates RBV IEA Sus scrofa 4554 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 4554 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 4554 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 4554 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4554 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4554 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 4554 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 4554 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 4554 R-XTR-2162066 https://reactome.org/PathwayBrowser/#/R-XTR-2162066 carbovir + IMP => carbovir monophosphate + inosine IEA Xenopus tropicalis 4554 R-XTR-5693346 https://reactome.org/PathwayBrowser/#/R-XTR-5693346 CECRI deaminates Ade-Rib to Ino IEA Xenopus tropicalis 4554 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 4554 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 4554 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 4554 R-XTR-9754916 https://reactome.org/PathwayBrowser/#/R-XTR-9754916 NT5C2 tetramer phosphorylates RBV IEA Xenopus tropicalis 4555 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4555 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4555 R-BTA-110251 https://reactome.org/PathwayBrowser/#/R-BTA-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Bos taurus 4555 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 4555 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 4555 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 4555 R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 4555 R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 4555 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4555 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4555 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 4555 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 4555 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 4555 R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 4555 R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 4555 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4555 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4555 R-CFA-110251 https://reactome.org/PathwayBrowser/#/R-CFA-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Canis familiaris 4555 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 4555 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 4555 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 4555 R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 4555 R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 4555 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4555 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4555 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 4555 R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 4555 R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 4555 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4555 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4555 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 4555 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 4555 R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 4555 R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 4555 R-DRE-110251 https://reactome.org/PathwayBrowser/#/R-DRE-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Danio rerio 4555 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 4555 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 4555 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 4555 R-GGA-110251 https://reactome.org/PathwayBrowser/#/R-GGA-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Gallus gallus 4555 R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 4555 R-GGA-421174 https://reactome.org/PathwayBrowser/#/R-GGA-421174 inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate IEA Gallus gallus 4555 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 4555 R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 4555 R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 4555 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4555 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4555 R-HSA-110251 https://reactome.org/PathwayBrowser/#/R-HSA-110251 Cleavage of hypoxanthine by MPG glycosylase TAS Homo sapiens 4555 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 4555 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 4555 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 4555 R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 4555 R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 4555 R-HSA-9734274 https://reactome.org/PathwayBrowser/#/R-HSA-9734274 Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 4555 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4555 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4555 R-MMU-110251 https://reactome.org/PathwayBrowser/#/R-MMU-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Mus musculus 4555 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 4555 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 4555 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 4555 R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 4555 R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 4555 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4555 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4555 R-PFA-110251 https://reactome.org/PathwayBrowser/#/R-PFA-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Plasmodium falciparum 4555 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 4555 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4555 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4555 R-RNO-110251 https://reactome.org/PathwayBrowser/#/R-RNO-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Rattus norvegicus 4555 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 4555 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 4555 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 4555 R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 4555 R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 4555 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 4555 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 4555 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 4555 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 4555 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4555 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4555 R-SSC-110251 https://reactome.org/PathwayBrowser/#/R-SSC-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Sus scrofa 4555 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 4555 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 4555 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 4555 R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 4555 R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 4555 R-XTR-110251 https://reactome.org/PathwayBrowser/#/R-XTR-110251 Cleavage of hypoxanthine by MPG glycosylase IEA Xenopus tropicalis 4555 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 4555 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 4555 R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 4555 R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 4556 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4556 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4556 R-BTA-112034 https://reactome.org/PathwayBrowser/#/R-BTA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Bos taurus 4556 R-BTA-74215 https://reactome.org/PathwayBrowser/#/R-BTA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Bos taurus 4556 R-BTA-74249 https://reactome.org/PathwayBrowser/#/R-BTA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Bos taurus 4556 R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 4556 R-BTA-8953339 https://reactome.org/PathwayBrowser/#/R-BTA-8953339 DNPH1 hydrolyses dGMP IEA Bos taurus 4556 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4556 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4556 R-CEL-112034 https://reactome.org/PathwayBrowser/#/R-CEL-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Caenorhabditis elegans 4556 R-CEL-74215 https://reactome.org/PathwayBrowser/#/R-CEL-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Caenorhabditis elegans 4556 R-CEL-74249 https://reactome.org/PathwayBrowser/#/R-CEL-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Caenorhabditis elegans 4556 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4556 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4556 R-CFA-112034 https://reactome.org/PathwayBrowser/#/R-CFA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Canis familiaris 4556 R-CFA-74215 https://reactome.org/PathwayBrowser/#/R-CFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Canis familiaris 4556 R-CFA-74249 https://reactome.org/PathwayBrowser/#/R-CFA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Canis familiaris 4556 R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 4556 R-CFA-8953339 https://reactome.org/PathwayBrowser/#/R-CFA-8953339 DNPH1 hydrolyses dGMP IEA Canis familiaris 4556 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4556 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4556 R-DDI-74215 https://reactome.org/PathwayBrowser/#/R-DDI-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Dictyostelium discoideum 4556 R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 4556 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4556 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4556 R-DME-112034 https://reactome.org/PathwayBrowser/#/R-DME-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Drosophila melanogaster 4556 R-DME-74249 https://reactome.org/PathwayBrowser/#/R-DME-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Drosophila melanogaster 4556 R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 4556 R-DRE-112034 https://reactome.org/PathwayBrowser/#/R-DRE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Danio rerio 4556 R-DRE-74215 https://reactome.org/PathwayBrowser/#/R-DRE-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Danio rerio 4556 R-DRE-74249 https://reactome.org/PathwayBrowser/#/R-DRE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Danio rerio 4556 R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 4556 R-DRE-8953339 https://reactome.org/PathwayBrowser/#/R-DRE-8953339 DNPH1 hydrolyses dGMP IEA Danio rerio 4556 R-GGA-74215 https://reactome.org/PathwayBrowser/#/R-GGA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Gallus gallus 4556 R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 4556 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4556 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4556 R-HSA-112034 https://reactome.org/PathwayBrowser/#/R-HSA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine TAS Homo sapiens 4556 R-HSA-6782443 https://reactome.org/PathwayBrowser/#/R-HSA-6782443 QTRT1:QTRTD1 exchanges guanine for queuine at guanosine-34 of tRNA(Asn),tRNA(Asp),tRNA(His),tRNA(Tyr) yielding queuosine-34 tRNA(Asn),tRNA(Asp),tRNA(His),tRNA(Tyr) TAS Homo sapiens 4556 R-HSA-74215 https://reactome.org/PathwayBrowser/#/R-HSA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 4556 R-HSA-74249 https://reactome.org/PathwayBrowser/#/R-HSA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 4556 R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 4556 R-HSA-8953339 https://reactome.org/PathwayBrowser/#/R-HSA-8953339 DNPH1 hydrolyses dGMP TAS Homo sapiens 4556 R-HSA-9734274 https://reactome.org/PathwayBrowser/#/R-HSA-9734274 Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP TAS Homo sapiens 4556 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4556 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4556 R-MMU-112034 https://reactome.org/PathwayBrowser/#/R-MMU-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Mus musculus 4556 R-MMU-74215 https://reactome.org/PathwayBrowser/#/R-MMU-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Mus musculus 4556 R-MMU-74249 https://reactome.org/PathwayBrowser/#/R-MMU-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Mus musculus 4556 R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 4556 R-MMU-8953339 https://reactome.org/PathwayBrowser/#/R-MMU-8953339 DNPH1 hydrolyses dGMP IEA Mus musculus 4556 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4556 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4556 R-PFA-74215 https://reactome.org/PathwayBrowser/#/R-PFA-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Plasmodium falciparum 4556 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4556 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4556 R-RNO-112034 https://reactome.org/PathwayBrowser/#/R-RNO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Rattus norvegicus 4556 R-RNO-74215 https://reactome.org/PathwayBrowser/#/R-RNO-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Rattus norvegicus 4556 R-RNO-74249 https://reactome.org/PathwayBrowser/#/R-RNO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Rattus norvegicus 4556 R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 4556 R-RNO-8953339 https://reactome.org/PathwayBrowser/#/R-RNO-8953339 DNPH1 hydrolyses dGMP IEA Rattus norvegicus 4556 R-SCE-112034 https://reactome.org/PathwayBrowser/#/R-SCE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Saccharomyces cerevisiae 4556 R-SCE-74249 https://reactome.org/PathwayBrowser/#/R-SCE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Saccharomyces cerevisiae 4556 R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 4556 R-SPO-112034 https://reactome.org/PathwayBrowser/#/R-SPO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Schizosaccharomyces pombe 4556 R-SPO-74249 https://reactome.org/PathwayBrowser/#/R-SPO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Schizosaccharomyces pombe 4556 R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 4556 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4556 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4556 R-SSC-112034 https://reactome.org/PathwayBrowser/#/R-SSC-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Sus scrofa 4556 R-SSC-74215 https://reactome.org/PathwayBrowser/#/R-SSC-74215 HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP IEA Sus scrofa 4556 R-SSC-74249 https://reactome.org/PathwayBrowser/#/R-SSC-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Sus scrofa 4556 R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 4556 R-SSC-8953339 https://reactome.org/PathwayBrowser/#/R-SSC-8953339 DNPH1 hydrolyses dGMP IEA Sus scrofa 4556 R-XTR-112034 https://reactome.org/PathwayBrowser/#/R-XTR-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Xenopus tropicalis 4556 R-XTR-74249 https://reactome.org/PathwayBrowser/#/R-XTR-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Xenopus tropicalis 4556 R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 4560 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4560 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4560 R-BTA-110218 https://reactome.org/PathwayBrowser/#/R-BTA-110218 Cleavage of uracil by TDG glycosylase IEA Bos taurus 4560 R-BTA-110221 https://reactome.org/PathwayBrowser/#/R-BTA-110221 Cleavage of uracil by SMUG1 glycosylase IEA Bos taurus 4560 R-BTA-110231 https://reactome.org/PathwayBrowser/#/R-BTA-110231 Cleavage of uracil by MBD4 glycosylase IEA Bos taurus 4560 R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 4560 R-BTA-74372 https://reactome.org/PathwayBrowser/#/R-BTA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Bos taurus 4560 R-BTA-74376 https://reactome.org/PathwayBrowser/#/R-BTA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Bos taurus 4560 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4560 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4560 R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 4560 R-CEL-74372 https://reactome.org/PathwayBrowser/#/R-CEL-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Caenorhabditis elegans 4560 R-CEL-74376 https://reactome.org/PathwayBrowser/#/R-CEL-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Caenorhabditis elegans 4560 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4560 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4560 R-CFA-110215 https://reactome.org/PathwayBrowser/#/R-CFA-110215 Cleavage of uracil by UNG glycosylase IEA Canis familiaris 4560 R-CFA-110218 https://reactome.org/PathwayBrowser/#/R-CFA-110218 Cleavage of uracil by TDG glycosylase IEA Canis familiaris 4560 R-CFA-110221 https://reactome.org/PathwayBrowser/#/R-CFA-110221 Cleavage of uracil by SMUG1 glycosylase IEA Canis familiaris 4560 R-CFA-110231 https://reactome.org/PathwayBrowser/#/R-CFA-110231 Cleavage of uracil by MBD4 glycosylase IEA Canis familiaris 4560 R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 4560 R-CFA-74372 https://reactome.org/PathwayBrowser/#/R-CFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Canis familiaris 4560 R-CFA-74376 https://reactome.org/PathwayBrowser/#/R-CFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Canis familiaris 4560 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4560 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4560 R-DDI-110215 https://reactome.org/PathwayBrowser/#/R-DDI-110215 Cleavage of uracil by UNG glycosylase IEA Dictyostelium discoideum 4560 R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 4560 R-DDI-74372 https://reactome.org/PathwayBrowser/#/R-DDI-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Dictyostelium discoideum 4560 R-DDI-74376 https://reactome.org/PathwayBrowser/#/R-DDI-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Dictyostelium discoideum 4560 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4560 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4560 R-DME-110218 https://reactome.org/PathwayBrowser/#/R-DME-110218 Cleavage of uracil by TDG glycosylase IEA Drosophila melanogaster 4560 R-DME-110221 https://reactome.org/PathwayBrowser/#/R-DME-110221 Cleavage of uracil by SMUG1 glycosylase IEA Drosophila melanogaster 4560 R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 4560 R-DME-74372 https://reactome.org/PathwayBrowser/#/R-DME-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Drosophila melanogaster 4560 R-DME-74376 https://reactome.org/PathwayBrowser/#/R-DME-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Drosophila melanogaster 4560 R-DRE-110215 https://reactome.org/PathwayBrowser/#/R-DRE-110215 Cleavage of uracil by UNG glycosylase IEA Danio rerio 4560 R-DRE-110218 https://reactome.org/PathwayBrowser/#/R-DRE-110218 Cleavage of uracil by TDG glycosylase IEA Danio rerio 4560 R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 4560 R-DRE-74372 https://reactome.org/PathwayBrowser/#/R-DRE-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Danio rerio 4560 R-DRE-74376 https://reactome.org/PathwayBrowser/#/R-DRE-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Danio rerio 4560 R-GGA-110215 https://reactome.org/PathwayBrowser/#/R-GGA-110215 Cleavage of uracil by UNG glycosylase IEA Gallus gallus 4560 R-GGA-110218 https://reactome.org/PathwayBrowser/#/R-GGA-110218 Cleavage of uracil by TDG glycosylase IEA Gallus gallus 4560 R-GGA-110221 https://reactome.org/PathwayBrowser/#/R-GGA-110221 Cleavage of uracil by SMUG1 glycosylase IEA Gallus gallus 4560 R-GGA-110231 https://reactome.org/PathwayBrowser/#/R-GGA-110231 Cleavage of uracil by MBD4 glycosylase IEA Gallus gallus 4560 R-GGA-353271 https://reactome.org/PathwayBrowser/#/R-GGA-353271 Cleavage of uracil by Uracil-glycosylase TAS Gallus gallus 4560 R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 4560 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus 4560 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus 4560 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4560 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4560 R-HSA-110215 https://reactome.org/PathwayBrowser/#/R-HSA-110215 Cleavage of uracil by UNG glycosylase TAS Homo sapiens 4560 R-HSA-110218 https://reactome.org/PathwayBrowser/#/R-HSA-110218 Cleavage of uracil by TDG glycosylase TAS Homo sapiens 4560 R-HSA-110221 https://reactome.org/PathwayBrowser/#/R-HSA-110221 Cleavage of uracil by SMUG1 glycosylase TAS Homo sapiens 4560 R-HSA-110231 https://reactome.org/PathwayBrowser/#/R-HSA-110231 Cleavage of uracil by MBD4 glycosylase TAS Homo sapiens 4560 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 4560 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 4560 R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 4560 R-HSA-74372 https://reactome.org/PathwayBrowser/#/R-HSA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] TAS Homo sapiens 4560 R-HSA-74376 https://reactome.org/PathwayBrowser/#/R-HSA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) TAS Homo sapiens 4560 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4560 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4560 R-MMU-110215 https://reactome.org/PathwayBrowser/#/R-MMU-110215 Cleavage of uracil by UNG glycosylase IEA Mus musculus 4560 R-MMU-110218 https://reactome.org/PathwayBrowser/#/R-MMU-110218 Cleavage of uracil by TDG glycosylase IEA Mus musculus 4560 R-MMU-110221 https://reactome.org/PathwayBrowser/#/R-MMU-110221 Cleavage of uracil by SMUG1 glycosylase IEA Mus musculus 4560 R-MMU-110231 https://reactome.org/PathwayBrowser/#/R-MMU-110231 Cleavage of uracil by MBD4 glycosylase IEA Mus musculus 4560 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 4560 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 4560 R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 4560 R-MMU-74372 https://reactome.org/PathwayBrowser/#/R-MMU-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Mus musculus 4560 R-MMU-74376 https://reactome.org/PathwayBrowser/#/R-MMU-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Mus musculus 4560 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4560 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4560 R-PFA-110215 https://reactome.org/PathwayBrowser/#/R-PFA-110215 Cleavage of uracil by UNG glycosylase IEA Plasmodium falciparum 4560 R-PFA-74372 https://reactome.org/PathwayBrowser/#/R-PFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Plasmodium falciparum 4560 R-PFA-74376 https://reactome.org/PathwayBrowser/#/R-PFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Plasmodium falciparum 4560 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4560 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4560 R-RNO-110215 https://reactome.org/PathwayBrowser/#/R-RNO-110215 Cleavage of uracil by UNG glycosylase IEA Rattus norvegicus 4560 R-RNO-110218 https://reactome.org/PathwayBrowser/#/R-RNO-110218 Cleavage of uracil by TDG glycosylase IEA Rattus norvegicus 4560 R-RNO-110221 https://reactome.org/PathwayBrowser/#/R-RNO-110221 Cleavage of uracil by SMUG1 glycosylase IEA Rattus norvegicus 4560 R-RNO-110231 https://reactome.org/PathwayBrowser/#/R-RNO-110231 Cleavage of uracil by MBD4 glycosylase IEA Rattus norvegicus 4560 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 4560 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 4560 R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 4560 R-RNO-74372 https://reactome.org/PathwayBrowser/#/R-RNO-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Rattus norvegicus 4560 R-RNO-74376 https://reactome.org/PathwayBrowser/#/R-RNO-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Rattus norvegicus 4560 R-SCE-110215 https://reactome.org/PathwayBrowser/#/R-SCE-110215 Cleavage of uracil by UNG glycosylase IEA Saccharomyces cerevisiae 4560 R-SPO-110215 https://reactome.org/PathwayBrowser/#/R-SPO-110215 Cleavage of uracil by UNG glycosylase IEA Schizosaccharomyces pombe 4560 R-SPO-110218 https://reactome.org/PathwayBrowser/#/R-SPO-110218 Cleavage of uracil by TDG glycosylase IEA Schizosaccharomyces pombe 4560 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4560 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4560 R-SSC-110215 https://reactome.org/PathwayBrowser/#/R-SSC-110215 Cleavage of uracil by UNG glycosylase IEA Sus scrofa 4560 R-SSC-110218 https://reactome.org/PathwayBrowser/#/R-SSC-110218 Cleavage of uracil by TDG glycosylase IEA Sus scrofa 4560 R-SSC-110221 https://reactome.org/PathwayBrowser/#/R-SSC-110221 Cleavage of uracil by SMUG1 glycosylase IEA Sus scrofa 4560 R-SSC-110231 https://reactome.org/PathwayBrowser/#/R-SSC-110231 Cleavage of uracil by MBD4 glycosylase IEA Sus scrofa 4560 R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 4560 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa 4560 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa 4560 R-XTR-110215 https://reactome.org/PathwayBrowser/#/R-XTR-110215 Cleavage of uracil by UNG glycosylase IEA Xenopus tropicalis 4560 R-XTR-110218 https://reactome.org/PathwayBrowser/#/R-XTR-110218 Cleavage of uracil by TDG glycosylase IEA Xenopus tropicalis 4560 R-XTR-110221 https://reactome.org/PathwayBrowser/#/R-XTR-110221 Cleavage of uracil by SMUG1 glycosylase IEA Xenopus tropicalis 4560 R-XTR-110231 https://reactome.org/PathwayBrowser/#/R-XTR-110231 Cleavage of uracil by MBD4 glycosylase IEA Xenopus tropicalis 4560 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 4560 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 4560 R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 4560 R-XTR-74372 https://reactome.org/PathwayBrowser/#/R-XTR-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Xenopus tropicalis 4560 R-XTR-74376 https://reactome.org/PathwayBrowser/#/R-XTR-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Xenopus tropicalis 4565 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 4565 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 4565 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 4565 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 4565 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 4565 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 4565 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 4565 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 4565 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 4565 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 4566 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 4566 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 4566 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 4566 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 4566 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 4566 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4566 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4566 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 4566 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4566 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4566 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 4566 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 4566 R-BTA-109903 https://reactome.org/PathwayBrowser/#/R-BTA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Bos taurus 4566 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 4566 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 4566 R-BTA-73599 https://reactome.org/PathwayBrowser/#/R-BTA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Bos taurus 4566 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 4566 R-BTA-74372 https://reactome.org/PathwayBrowser/#/R-BTA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Bos taurus 4566 R-BTA-74376 https://reactome.org/PathwayBrowser/#/R-BTA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Bos taurus 4566 R-BTA-8954327 https://reactome.org/PathwayBrowser/#/R-BTA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Bos taurus 4566 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 4566 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4566 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4566 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 4566 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4566 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4566 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 4566 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 4566 R-CEL-109903 https://reactome.org/PathwayBrowser/#/R-CEL-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Caenorhabditis elegans 4566 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 4566 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 4566 R-CEL-73599 https://reactome.org/PathwayBrowser/#/R-CEL-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Caenorhabditis elegans 4566 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 4566 R-CEL-74372 https://reactome.org/PathwayBrowser/#/R-CEL-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Caenorhabditis elegans 4566 R-CEL-74376 https://reactome.org/PathwayBrowser/#/R-CEL-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Caenorhabditis elegans 4566 R-CEL-8954327 https://reactome.org/PathwayBrowser/#/R-CEL-8954327 UCKL1 phosphorylates urindine, cytidine IEA Caenorhabditis elegans 4566 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 4566 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 4566 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 4566 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 4566 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 4566 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4566 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4566 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4566 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4566 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 4566 R-CFA-109903 https://reactome.org/PathwayBrowser/#/R-CFA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Canis familiaris 4566 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 4566 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 4566 R-CFA-73599 https://reactome.org/PathwayBrowser/#/R-CFA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Canis familiaris 4566 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 4566 R-CFA-74372 https://reactome.org/PathwayBrowser/#/R-CFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Canis familiaris 4566 R-CFA-74376 https://reactome.org/PathwayBrowser/#/R-CFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Canis familiaris 4566 R-CFA-8954327 https://reactome.org/PathwayBrowser/#/R-CFA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Canis familiaris 4566 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4566 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4566 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4566 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4566 R-DDI-109903 https://reactome.org/PathwayBrowser/#/R-DDI-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Dictyostelium discoideum 4566 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 4566 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 4566 R-DDI-73599 https://reactome.org/PathwayBrowser/#/R-DDI-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Dictyostelium discoideum 4566 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 4566 R-DDI-74372 https://reactome.org/PathwayBrowser/#/R-DDI-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Dictyostelium discoideum 4566 R-DDI-74376 https://reactome.org/PathwayBrowser/#/R-DDI-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Dictyostelium discoideum 4566 R-DDI-8954327 https://reactome.org/PathwayBrowser/#/R-DDI-8954327 UCKL1 phosphorylates urindine, cytidine IEA Dictyostelium discoideum 4566 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 4566 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 4566 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4566 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4566 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 4566 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4566 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4566 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 4566 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 4566 R-DME-109903 https://reactome.org/PathwayBrowser/#/R-DME-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Drosophila melanogaster 4566 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 4566 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 4566 R-DME-73599 https://reactome.org/PathwayBrowser/#/R-DME-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Drosophila melanogaster 4566 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 4566 R-DME-74372 https://reactome.org/PathwayBrowser/#/R-DME-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Drosophila melanogaster 4566 R-DME-74376 https://reactome.org/PathwayBrowser/#/R-DME-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Drosophila melanogaster 4566 R-DME-8954327 https://reactome.org/PathwayBrowser/#/R-DME-8954327 UCKL1 phosphorylates urindine, cytidine IEA Drosophila melanogaster 4566 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 4566 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 4566 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 4566 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4566 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4566 R-DRE-109903 https://reactome.org/PathwayBrowser/#/R-DRE-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Danio rerio 4566 R-DRE-73599 https://reactome.org/PathwayBrowser/#/R-DRE-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Danio rerio 4566 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 4566 R-DRE-74372 https://reactome.org/PathwayBrowser/#/R-DRE-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Danio rerio 4566 R-DRE-74376 https://reactome.org/PathwayBrowser/#/R-DRE-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Danio rerio 4566 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 4566 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 4566 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 4566 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 4566 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 4566 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 4566 R-GGA-109903 https://reactome.org/PathwayBrowser/#/R-GGA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Gallus gallus 4566 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 4566 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 4566 R-GGA-73599 https://reactome.org/PathwayBrowser/#/R-GGA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Gallus gallus 4566 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 4566 R-GGA-74372 https://reactome.org/PathwayBrowser/#/R-GGA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Gallus gallus 4566 R-GGA-74376 https://reactome.org/PathwayBrowser/#/R-GGA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Gallus gallus 4566 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus 4566 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 4566 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 4566 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 4566 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 4566 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 4566 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4566 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4566 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 4566 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4566 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4566 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 4566 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 4566 R-HSA-109903 https://reactome.org/PathwayBrowser/#/R-HSA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] TAS Homo sapiens 4566 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4566 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4566 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 4566 R-HSA-73599 https://reactome.org/PathwayBrowser/#/R-HSA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] TAS Homo sapiens 4566 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 4566 R-HSA-74372 https://reactome.org/PathwayBrowser/#/R-HSA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] TAS Homo sapiens 4566 R-HSA-74376 https://reactome.org/PathwayBrowser/#/R-HSA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) TAS Homo sapiens 4566 R-HSA-8954327 https://reactome.org/PathwayBrowser/#/R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine TAS Homo sapiens 4566 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 4566 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 4566 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 4566 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 4566 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 4566 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4566 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4566 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 4566 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4566 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4566 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 4566 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 4566 R-MMU-109903 https://reactome.org/PathwayBrowser/#/R-MMU-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Mus musculus 4566 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 4566 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 4566 R-MMU-73599 https://reactome.org/PathwayBrowser/#/R-MMU-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Mus musculus 4566 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 4566 R-MMU-74372 https://reactome.org/PathwayBrowser/#/R-MMU-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Mus musculus 4566 R-MMU-74376 https://reactome.org/PathwayBrowser/#/R-MMU-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Mus musculus 4566 R-MMU-8954327 https://reactome.org/PathwayBrowser/#/R-MMU-8954327 UCKL1 phosphorylates urindine, cytidine IEA Mus musculus 4566 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4566 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4566 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4566 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4566 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 4566 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 4566 R-PFA-74372 https://reactome.org/PathwayBrowser/#/R-PFA-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Plasmodium falciparum 4566 R-PFA-74376 https://reactome.org/PathwayBrowser/#/R-PFA-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Plasmodium falciparum 4566 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 4566 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 4566 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 4566 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 4566 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 4566 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4566 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4566 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 4566 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4566 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4566 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 4566 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 4566 R-RNO-109903 https://reactome.org/PathwayBrowser/#/R-RNO-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Rattus norvegicus 4566 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 4566 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 4566 R-RNO-73599 https://reactome.org/PathwayBrowser/#/R-RNO-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Rattus norvegicus 4566 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 4566 R-RNO-74372 https://reactome.org/PathwayBrowser/#/R-RNO-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Rattus norvegicus 4566 R-RNO-74376 https://reactome.org/PathwayBrowser/#/R-RNO-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Rattus norvegicus 4566 R-RNO-8954327 https://reactome.org/PathwayBrowser/#/R-RNO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Rattus norvegicus 4566 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 4566 R-SCE-8954327 https://reactome.org/PathwayBrowser/#/R-SCE-8954327 UCKL1 phosphorylates urindine, cytidine IEA Saccharomyces cerevisiae 4566 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 4566 R-SPO-8954327 https://reactome.org/PathwayBrowser/#/R-SPO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Schizosaccharomyces pombe 4566 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 4566 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 4566 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 4566 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 4566 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 4566 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4566 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4566 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 4566 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4566 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4566 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 4566 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 4566 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa 4566 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 4566 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 4566 R-SSC-73599 https://reactome.org/PathwayBrowser/#/R-SSC-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Sus scrofa 4566 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 4566 R-SSC-74372 https://reactome.org/PathwayBrowser/#/R-SSC-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Sus scrofa 4566 R-SSC-74376 https://reactome.org/PathwayBrowser/#/R-SSC-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Sus scrofa 4566 R-SSC-8954327 https://reactome.org/PathwayBrowser/#/R-SSC-8954327 UCKL1 phosphorylates urindine, cytidine IEA Sus scrofa 4566 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 4566 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 4566 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 4566 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 4566 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 4566 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 4566 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4566 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4566 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 4566 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 4566 R-XTR-109903 https://reactome.org/PathwayBrowser/#/R-XTR-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Xenopus tropicalis 4566 R-XTR-73599 https://reactome.org/PathwayBrowser/#/R-XTR-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Xenopus tropicalis 4566 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 4566 R-XTR-74372 https://reactome.org/PathwayBrowser/#/R-XTR-74372 uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] IEA Xenopus tropicalis 4566 R-XTR-74376 https://reactome.org/PathwayBrowser/#/R-XTR-74376 (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) IEA Xenopus tropicalis 4566 R-XTR-8954327 https://reactome.org/PathwayBrowser/#/R-XTR-8954327 UCKL1 phosphorylates urindine, cytidine IEA Xenopus tropicalis 4567 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 4567 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 4567 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 4567 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4567 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4567 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4567 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4567 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 4567 R-BTA-109539 https://reactome.org/PathwayBrowser/#/R-BTA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Bos taurus 4567 R-BTA-112034 https://reactome.org/PathwayBrowser/#/R-BTA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Bos taurus 4567 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 4567 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 4567 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 4567 R-BTA-74249 https://reactome.org/PathwayBrowser/#/R-BTA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Bos taurus 4567 R-BTA-9824732 https://reactome.org/PathwayBrowser/#/R-BTA-9824732 G or G analog binds C-ter TLR7 dimer IEA Bos taurus 4567 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4567 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4567 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4567 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4567 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 4567 R-CEL-109539 https://reactome.org/PathwayBrowser/#/R-CEL-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Caenorhabditis elegans 4567 R-CEL-112034 https://reactome.org/PathwayBrowser/#/R-CEL-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Caenorhabditis elegans 4567 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 4567 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 4567 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 4567 R-CEL-74249 https://reactome.org/PathwayBrowser/#/R-CEL-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Caenorhabditis elegans 4567 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 4567 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 4567 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 4567 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4567 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4567 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4567 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4567 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 4567 R-CFA-112034 https://reactome.org/PathwayBrowser/#/R-CFA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Canis familiaris 4567 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 4567 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 4567 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 4567 R-CFA-74249 https://reactome.org/PathwayBrowser/#/R-CFA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Canis familiaris 4567 R-CFA-9824732 https://reactome.org/PathwayBrowser/#/R-CFA-9824732 G or G analog binds C-ter TLR7 dimer IEA Canis familiaris 4567 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4567 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4567 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4567 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4567 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 4567 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 4567 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 4567 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 4567 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4567 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4567 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4567 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4567 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 4567 R-DME-109539 https://reactome.org/PathwayBrowser/#/R-DME-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Drosophila melanogaster 4567 R-DME-112034 https://reactome.org/PathwayBrowser/#/R-DME-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Drosophila melanogaster 4567 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 4567 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 4567 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 4567 R-DME-74249 https://reactome.org/PathwayBrowser/#/R-DME-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Drosophila melanogaster 4567 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 4567 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 4567 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4567 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4567 R-DRE-112034 https://reactome.org/PathwayBrowser/#/R-DRE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Danio rerio 4567 R-DRE-74249 https://reactome.org/PathwayBrowser/#/R-DRE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Danio rerio 4567 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 4567 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 4567 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 4567 R-GGA-109539 https://reactome.org/PathwayBrowser/#/R-GGA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Gallus gallus 4567 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 4567 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 4567 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 4567 R-GGA-9824732 https://reactome.org/PathwayBrowser/#/R-GGA-9824732 G or G analog binds C-ter TLR7 dimer IEA Gallus gallus 4567 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 4567 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 4567 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 4567 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4567 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4567 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4567 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4567 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 4567 R-HSA-109539 https://reactome.org/PathwayBrowser/#/R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 TAS Homo sapiens 4567 R-HSA-112034 https://reactome.org/PathwayBrowser/#/R-HSA-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine TAS Homo sapiens 4567 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4567 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4567 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 4567 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 4567 R-HSA-74249 https://reactome.org/PathwayBrowser/#/R-HSA-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 4567 R-HSA-9735789 https://reactome.org/PathwayBrowser/#/R-HSA-9735789 Defective PNP does not convert (deoxy)guanosine to guanine and (deoxy)ribose TAS Homo sapiens 4567 R-HSA-975098 https://reactome.org/PathwayBrowser/#/R-HSA-975098 MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 TAS Homo sapiens 4567 R-HSA-975100 https://reactome.org/PathwayBrowser/#/R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex TAS Homo sapiens 4567 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 4567 R-HSA-975111 https://reactome.org/PathwayBrowser/#/R-HSA-975111 TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 4567 R-HSA-975115 https://reactome.org/PathwayBrowser/#/R-HSA-975115 IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 4567 R-HSA-975118 https://reactome.org/PathwayBrowser/#/R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex TAS Homo sapiens 4567 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 4567 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 4567 R-HSA-975156 https://reactome.org/PathwayBrowser/#/R-HSA-975156 IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex TAS Homo sapiens 4567 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 4567 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 4567 R-HSA-975175 https://reactome.org/PathwayBrowser/#/R-HSA-975175 MyD88 interacts with the activated TLR receptor 7, 8 or 9 TAS Homo sapiens 4567 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 4567 R-HSA-975188 https://reactome.org/PathwayBrowser/#/R-HSA-975188 TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 4567 R-HSA-9824732 https://reactome.org/PathwayBrowser/#/R-HSA-9824732 G or G analog binds C-ter TLR7 dimer TAS Homo sapiens 4567 R-HSA-9824849 https://reactome.org/PathwayBrowser/#/R-HSA-9824849 G or G analog binds C-ter TLR7 GoF variant TAS Homo sapiens 4567 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 4567 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 4567 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 4567 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4567 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4567 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4567 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4567 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 4567 R-MMU-109539 https://reactome.org/PathwayBrowser/#/R-MMU-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Mus musculus 4567 R-MMU-112034 https://reactome.org/PathwayBrowser/#/R-MMU-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Mus musculus 4567 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 4567 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 4567 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 4567 R-MMU-74249 https://reactome.org/PathwayBrowser/#/R-MMU-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Mus musculus 4567 R-MMU-9824732 https://reactome.org/PathwayBrowser/#/R-MMU-9824732 G or G analog binds C-ter TLR7 dimer IEA Mus musculus 4567 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4567 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4567 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4567 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4567 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 4567 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 4567 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 4567 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 4567 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 4567 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4567 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4567 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4567 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4567 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 4567 R-RNO-109539 https://reactome.org/PathwayBrowser/#/R-RNO-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Rattus norvegicus 4567 R-RNO-112034 https://reactome.org/PathwayBrowser/#/R-RNO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Rattus norvegicus 4567 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 4567 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 4567 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 4567 R-RNO-74249 https://reactome.org/PathwayBrowser/#/R-RNO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Rattus norvegicus 4567 R-RNO-9824732 https://reactome.org/PathwayBrowser/#/R-RNO-9824732 G or G analog binds C-ter TLR7 dimer IEA Rattus norvegicus 4567 R-SCE-112034 https://reactome.org/PathwayBrowser/#/R-SCE-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Saccharomyces cerevisiae 4567 R-SCE-74249 https://reactome.org/PathwayBrowser/#/R-SCE-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Saccharomyces cerevisiae 4567 R-SPO-112034 https://reactome.org/PathwayBrowser/#/R-SPO-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Schizosaccharomyces pombe 4567 R-SPO-74249 https://reactome.org/PathwayBrowser/#/R-SPO-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Schizosaccharomyces pombe 4567 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 4567 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 4567 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 4567 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4567 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4567 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4567 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4567 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 4567 R-SSC-109539 https://reactome.org/PathwayBrowser/#/R-SSC-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Sus scrofa 4567 R-SSC-112034 https://reactome.org/PathwayBrowser/#/R-SSC-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Sus scrofa 4567 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 4567 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 4567 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 4567 R-SSC-74249 https://reactome.org/PathwayBrowser/#/R-SSC-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Sus scrofa 4567 R-SSC-9824732 https://reactome.org/PathwayBrowser/#/R-SSC-9824732 G or G analog binds C-ter TLR7 dimer IEA Sus scrofa 4567 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 4567 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 4567 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 4567 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4567 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4567 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 4567 R-XTR-109539 https://reactome.org/PathwayBrowser/#/R-XTR-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 IEA Xenopus tropicalis 4567 R-XTR-112034 https://reactome.org/PathwayBrowser/#/R-XTR-112034 PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine IEA Xenopus tropicalis 4567 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 4567 R-XTR-74249 https://reactome.org/PathwayBrowser/#/R-XTR-74249 PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose IEA Xenopus tropicalis 4567 R-XTR-9824732 https://reactome.org/PathwayBrowser/#/R-XTR-9824732 G or G analog binds C-ter TLR7 dimer IEA Xenopus tropicalis 4578 R-BTA-6787533 https://reactome.org/PathwayBrowser/#/R-BTA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Bos taurus 4578 R-BTA-6787642 https://reactome.org/PathwayBrowser/#/R-BTA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Bos taurus 4578 R-BTA-742345 https://reactome.org/PathwayBrowser/#/R-BTA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Bos taurus 4578 R-CEL-6787533 https://reactome.org/PathwayBrowser/#/R-CEL-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Caenorhabditis elegans 4578 R-CEL-6787642 https://reactome.org/PathwayBrowser/#/R-CEL-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Caenorhabditis elegans 4578 R-CEL-742345 https://reactome.org/PathwayBrowser/#/R-CEL-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Caenorhabditis elegans 4578 R-CFA-6787533 https://reactome.org/PathwayBrowser/#/R-CFA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Canis familiaris 4578 R-CFA-6787642 https://reactome.org/PathwayBrowser/#/R-CFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Canis familiaris 4578 R-CFA-742345 https://reactome.org/PathwayBrowser/#/R-CFA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Canis familiaris 4578 R-DDI-6787533 https://reactome.org/PathwayBrowser/#/R-DDI-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Dictyostelium discoideum 4578 R-DDI-6787642 https://reactome.org/PathwayBrowser/#/R-DDI-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Dictyostelium discoideum 4578 R-DDI-742345 https://reactome.org/PathwayBrowser/#/R-DDI-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Dictyostelium discoideum 4578 R-DME-6787642 https://reactome.org/PathwayBrowser/#/R-DME-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Drosophila melanogaster 4578 R-DME-742345 https://reactome.org/PathwayBrowser/#/R-DME-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Drosophila melanogaster 4578 R-DRE-6787642 https://reactome.org/PathwayBrowser/#/R-DRE-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Danio rerio 4578 R-GGA-6787533 https://reactome.org/PathwayBrowser/#/R-GGA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Gallus gallus 4578 R-GGA-6787642 https://reactome.org/PathwayBrowser/#/R-GGA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Gallus gallus 4578 R-GGA-742345 https://reactome.org/PathwayBrowser/#/R-GGA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Gallus gallus 4578 R-HSA-1912349 https://reactome.org/PathwayBrowser/#/R-HSA-1912349 Fucosylation of Pre-NOTCH by POFUT1 IEA Homo sapiens 4578 R-HSA-5653596 https://reactome.org/PathwayBrowser/#/R-HSA-5653596 Defective SLC35C1 does not transport UDP-Fuc from cytosol to Golgi lumen TAS Homo sapiens 4578 R-HSA-6787533 https://reactome.org/PathwayBrowser/#/R-HSA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc TAS Homo sapiens 4578 R-HSA-6787642 https://reactome.org/PathwayBrowser/#/R-HSA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc TAS Homo sapiens 4578 R-HSA-742345 https://reactome.org/PathwayBrowser/#/R-HSA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen TAS Homo sapiens 4578 R-MMU-6787533 https://reactome.org/PathwayBrowser/#/R-MMU-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Mus musculus 4578 R-MMU-6787642 https://reactome.org/PathwayBrowser/#/R-MMU-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Mus musculus 4578 R-MMU-742345 https://reactome.org/PathwayBrowser/#/R-MMU-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Mus musculus 4578 R-NUL-1986584 https://reactome.org/PathwayBrowser/#/R-NUL-1986584 Fucosylation of Pre-Notch by POFUT1 TAS Cricetulus griseus 4578 R-PFA-6787642 https://reactome.org/PathwayBrowser/#/R-PFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Plasmodium falciparum 4578 R-PFA-742345 https://reactome.org/PathwayBrowser/#/R-PFA-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Plasmodium falciparum 4578 R-RNO-6787533 https://reactome.org/PathwayBrowser/#/R-RNO-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Rattus norvegicus 4578 R-RNO-6787642 https://reactome.org/PathwayBrowser/#/R-RNO-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Rattus norvegicus 4578 R-RNO-742345 https://reactome.org/PathwayBrowser/#/R-RNO-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Rattus norvegicus 4578 R-SPO-742345 https://reactome.org/PathwayBrowser/#/R-SPO-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Schizosaccharomyces pombe 4578 R-SSC-6787533 https://reactome.org/PathwayBrowser/#/R-SSC-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Sus scrofa 4578 R-SSC-6787642 https://reactome.org/PathwayBrowser/#/R-SSC-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Sus scrofa 4578 R-SSC-742345 https://reactome.org/PathwayBrowser/#/R-SSC-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Sus scrofa 4578 R-XTR-6787533 https://reactome.org/PathwayBrowser/#/R-XTR-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Xenopus tropicalis 4578 R-XTR-6787642 https://reactome.org/PathwayBrowser/#/R-XTR-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Xenopus tropicalis 4578 R-XTR-742345 https://reactome.org/PathwayBrowser/#/R-XTR-742345 SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen IEA Xenopus tropicalis 4581 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4581 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4581 R-BTA-110219 https://reactome.org/PathwayBrowser/#/R-BTA-110219 Cleavage of thymine by TDG glycosylase IEA Bos taurus 4581 R-BTA-110232 https://reactome.org/PathwayBrowser/#/R-BTA-110232 Cleavage of thymine by MBD4 glycosylase IEA Bos taurus 4581 R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 4581 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4581 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4581 R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 4581 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4581 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4581 R-CFA-110219 https://reactome.org/PathwayBrowser/#/R-CFA-110219 Cleavage of thymine by TDG glycosylase IEA Canis familiaris 4581 R-CFA-110232 https://reactome.org/PathwayBrowser/#/R-CFA-110232 Cleavage of thymine by MBD4 glycosylase IEA Canis familiaris 4581 R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 4581 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4581 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4581 R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 4581 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4581 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4581 R-DME-110219 https://reactome.org/PathwayBrowser/#/R-DME-110219 Cleavage of thymine by TDG glycosylase IEA Drosophila melanogaster 4581 R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 4581 R-DRE-110219 https://reactome.org/PathwayBrowser/#/R-DRE-110219 Cleavage of thymine by TDG glycosylase IEA Danio rerio 4581 R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 4581 R-GGA-110219 https://reactome.org/PathwayBrowser/#/R-GGA-110219 Cleavage of thymine by TDG glycosylase IEA Gallus gallus 4581 R-GGA-110232 https://reactome.org/PathwayBrowser/#/R-GGA-110232 Cleavage of thymine by MBD4 glycosylase IEA Gallus gallus 4581 R-GGA-353277 https://reactome.org/PathwayBrowser/#/R-GGA-353277 Cleavage of thymine by 5-methylcytosine G/T mismatch specific glycosylase TAS Gallus gallus 4581 R-GGA-353444 https://reactome.org/PathwayBrowser/#/R-GGA-353444 Cleavage of thymine by TDG glycosylase TAS Gallus gallus 4581 R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 4581 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4581 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4581 R-HSA-110219 https://reactome.org/PathwayBrowser/#/R-HSA-110219 Cleavage of thymine by TDG glycosylase TAS Homo sapiens 4581 R-HSA-110232 https://reactome.org/PathwayBrowser/#/R-HSA-110232 Cleavage of thymine by MBD4 glycosylase TAS Homo sapiens 4581 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 4581 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 4581 R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 4581 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4581 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4581 R-MMU-110219 https://reactome.org/PathwayBrowser/#/R-MMU-110219 Cleavage of thymine by TDG glycosylase IEA Mus musculus 4581 R-MMU-110232 https://reactome.org/PathwayBrowser/#/R-MMU-110232 Cleavage of thymine by MBD4 glycosylase IEA Mus musculus 4581 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 4581 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 4581 R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 4581 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4581 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4581 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4581 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4581 R-RNO-110219 https://reactome.org/PathwayBrowser/#/R-RNO-110219 Cleavage of thymine by TDG glycosylase IEA Rattus norvegicus 4581 R-RNO-110232 https://reactome.org/PathwayBrowser/#/R-RNO-110232 Cleavage of thymine by MBD4 glycosylase IEA Rattus norvegicus 4581 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 4581 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 4581 R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 4581 R-SPO-110219 https://reactome.org/PathwayBrowser/#/R-SPO-110219 Cleavage of thymine by TDG glycosylase IEA Schizosaccharomyces pombe 4581 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4581 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4581 R-SSC-110219 https://reactome.org/PathwayBrowser/#/R-SSC-110219 Cleavage of thymine by TDG glycosylase IEA Sus scrofa 4581 R-SSC-110232 https://reactome.org/PathwayBrowser/#/R-SSC-110232 Cleavage of thymine by MBD4 glycosylase IEA Sus scrofa 4581 R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 4581 R-XTR-110219 https://reactome.org/PathwayBrowser/#/R-XTR-110219 Cleavage of thymine by TDG glycosylase IEA Xenopus tropicalis 4581 R-XTR-110232 https://reactome.org/PathwayBrowser/#/R-XTR-110232 Cleavage of thymine by MBD4 glycosylase IEA Xenopus tropicalis 4581 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 4581 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 4581 R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 4582 R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 4582 R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 4582 R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 4582 R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 4582 R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 4582 R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 4582 R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 4582 R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 4585 R-BTA-422104 https://reactome.org/PathwayBrowser/#/R-BTA-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Bos taurus 4585 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 4585 R-CFA-422104 https://reactome.org/PathwayBrowser/#/R-CFA-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Canis familiaris 4585 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 4585 R-DRE-422104 https://reactome.org/PathwayBrowser/#/R-DRE-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Danio rerio 4585 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 4585 R-GGA-422104 https://reactome.org/PathwayBrowser/#/R-GGA-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Gallus gallus 4585 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 4585 R-HSA-422104 https://reactome.org/PathwayBrowser/#/R-HSA-422104 Ghrelin O-acyltransferase octanoylates Proghrelin TAS Homo sapiens 4585 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 4585 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 4585 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 4585 R-MMU-422104 https://reactome.org/PathwayBrowser/#/R-MMU-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Mus musculus 4585 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 4585 R-RNO-422104 https://reactome.org/PathwayBrowser/#/R-RNO-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Rattus norvegicus 4585 R-SSC-422104 https://reactome.org/PathwayBrowser/#/R-SSC-422104 Ghrelin O-acyltransferase octanoylates Proghrelin IEA Sus scrofa 4585 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 4586 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 4586 R-HSA-9686790 https://reactome.org/PathwayBrowser/#/R-HSA-9686790 ER-alpha glucosidases bind ER-alpha glucosidase inhibitors TAS Homo sapiens 4586 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 4594 R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 4594 R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 4594 R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 4594 R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 4594 R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 4594 R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 4594 R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 4594 R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 463 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 463 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 463 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 463 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 463 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 463 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 463 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 463 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 463 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 463 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 4642 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 4642 R-HSA-9686790 https://reactome.org/PathwayBrowser/#/R-HSA-9686790 ER-alpha glucosidases bind ER-alpha glucosidase inhibitors TAS Homo sapiens 4642 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 4644 R-HSA-168272 https://reactome.org/PathwayBrowser/#/R-HSA-168272 Binding of the influenza virion to the host cell TAS Homo sapiens 4644 R-HSA-168285 https://reactome.org/PathwayBrowser/#/R-HSA-168285 Clathrin-Mediated Pit Formation And Endocytosis Of The Influenza Virion TAS Homo sapiens 4644 R-HSA-168860 https://reactome.org/PathwayBrowser/#/R-HSA-168860 Membrane fusion TAS Homo sapiens 4644 R-HSA-168870 https://reactome.org/PathwayBrowser/#/R-HSA-168870 Neuraminidase enzymatic release from sialic acid TAS Homo sapiens 4645 R-BTA-429571 https://reactome.org/PathwayBrowser/#/R-BTA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Bos taurus 4645 R-CFA-429571 https://reactome.org/PathwayBrowser/#/R-CFA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Canis familiaris 4645 R-DRE-429571 https://reactome.org/PathwayBrowser/#/R-DRE-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Danio rerio 4645 R-GGA-429571 https://reactome.org/PathwayBrowser/#/R-GGA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Gallus gallus 4645 R-HSA-429571 https://reactome.org/PathwayBrowser/#/R-HSA-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 TAS Homo sapiens 4645 R-MMU-429571 https://reactome.org/PathwayBrowser/#/R-MMU-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Mus musculus 4645 R-RNO-429571 https://reactome.org/PathwayBrowser/#/R-RNO-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Rattus norvegicus 4645 R-SSC-429571 https://reactome.org/PathwayBrowser/#/R-SSC-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Sus scrofa 4645 R-XTR-429571 https://reactome.org/PathwayBrowser/#/R-XTR-429571 Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 IEA Xenopus tropicalis 4646 R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 4646 R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 4646 R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 4646 R-BTA-1630306 https://reactome.org/PathwayBrowser/#/R-BTA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Bos taurus 4646 R-BTA-2090079 https://reactome.org/PathwayBrowser/#/R-BTA-2090079 GLB1 hydrolyses linker chain(2) IEA Bos taurus 4646 R-BTA-70355 https://reactome.org/PathwayBrowser/#/R-BTA-70355 GALK1 phosphorylates Gal to Gal1P IEA Bos taurus 4646 R-BTA-9840795 https://reactome.org/PathwayBrowser/#/R-BTA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Bos taurus 4646 R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 4646 R-BTA-9931853 https://reactome.org/PathwayBrowser/#/R-BTA-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Bos taurus 4646 R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 4646 R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 4646 R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 4646 R-CEL-1630306 https://reactome.org/PathwayBrowser/#/R-CEL-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Caenorhabditis elegans 4646 R-CEL-2090079 https://reactome.org/PathwayBrowser/#/R-CEL-2090079 GLB1 hydrolyses linker chain(2) IEA Caenorhabditis elegans 4646 R-CEL-9840795 https://reactome.org/PathwayBrowser/#/R-CEL-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Caenorhabditis elegans 4646 R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 4646 R-CEL-9931853 https://reactome.org/PathwayBrowser/#/R-CEL-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Caenorhabditis elegans 4646 R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 4646 R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 4646 R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 4646 R-CFA-1630306 https://reactome.org/PathwayBrowser/#/R-CFA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Canis familiaris 4646 R-CFA-2090079 https://reactome.org/PathwayBrowser/#/R-CFA-2090079 GLB1 hydrolyses linker chain(2) IEA Canis familiaris 4646 R-CFA-70355 https://reactome.org/PathwayBrowser/#/R-CFA-70355 GALK1 phosphorylates Gal to Gal1P IEA Canis familiaris 4646 R-CFA-9840795 https://reactome.org/PathwayBrowser/#/R-CFA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Canis familiaris 4646 R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 4646 R-CFA-9931853 https://reactome.org/PathwayBrowser/#/R-CFA-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Canis familiaris 4646 R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 4646 R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 4646 R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 4646 R-DDI-1630306 https://reactome.org/PathwayBrowser/#/R-DDI-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Dictyostelium discoideum 4646 R-DDI-2090079 https://reactome.org/PathwayBrowser/#/R-DDI-2090079 GLB1 hydrolyses linker chain(2) IEA Dictyostelium discoideum 4646 R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 4646 R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 4646 R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 4646 R-DME-1630306 https://reactome.org/PathwayBrowser/#/R-DME-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Drosophila melanogaster 4646 R-DME-2090079 https://reactome.org/PathwayBrowser/#/R-DME-2090079 GLB1 hydrolyses linker chain(2) IEA Drosophila melanogaster 4646 R-DME-9931853 https://reactome.org/PathwayBrowser/#/R-DME-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Drosophila melanogaster 4646 R-DRE-70355 https://reactome.org/PathwayBrowser/#/R-DRE-70355 GALK1 phosphorylates Gal to Gal1P IEA Danio rerio 4646 R-DRE-9931853 https://reactome.org/PathwayBrowser/#/R-DRE-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Danio rerio 4646 R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 4646 R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 4646 R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 4646 R-GGA-1630306 https://reactome.org/PathwayBrowser/#/R-GGA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Gallus gallus 4646 R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus 4646 R-GGA-70355 https://reactome.org/PathwayBrowser/#/R-GGA-70355 GALK1 phosphorylates Gal to Gal1P IEA Gallus gallus 4646 R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 4646 R-GGA-9931853 https://reactome.org/PathwayBrowser/#/R-GGA-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Gallus gallus 4646 R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 4646 R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 4646 R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 4646 R-HSA-1630306 https://reactome.org/PathwayBrowser/#/R-HSA-1630306 GLB1 hydrolyses a glycosaminoglycan TAS Homo sapiens 4646 R-HSA-2090079 https://reactome.org/PathwayBrowser/#/R-HSA-2090079 GLB1 hydrolyses linker chain(2) TAS Homo sapiens 4646 R-HSA-70355 https://reactome.org/PathwayBrowser/#/R-HSA-70355 GALK1 phosphorylates Gal to Gal1P TAS Homo sapiens 4646 R-HSA-9840795 https://reactome.org/PathwayBrowser/#/R-HSA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 TAS Homo sapiens 4646 R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 4646 R-HSA-9931850 https://reactome.org/PathwayBrowser/#/R-HSA-9931850 AKR1B1 reduces galactose to galactitol IEA Homo sapiens 4646 R-HSA-9931853 https://reactome.org/PathwayBrowser/#/R-HSA-9931853 GALM converts beta-D-GAL to alpha-D-GAL TAS Homo sapiens 4646 R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 4646 R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 4646 R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 4646 R-MMU-1630306 https://reactome.org/PathwayBrowser/#/R-MMU-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Mus musculus 4646 R-MMU-2090079 https://reactome.org/PathwayBrowser/#/R-MMU-2090079 GLB1 hydrolyses linker chain(2) IEA Mus musculus 4646 R-MMU-70355 https://reactome.org/PathwayBrowser/#/R-MMU-70355 GALK1 phosphorylates Gal to Gal1P IEA Mus musculus 4646 R-MMU-9840795 https://reactome.org/PathwayBrowser/#/R-MMU-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Mus musculus 4646 R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 4646 R-MMU-9931853 https://reactome.org/PathwayBrowser/#/R-MMU-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Mus musculus 4646 R-MMU-9931940 https://reactome.org/PathwayBrowser/#/R-MMU-9931940 Akr1b1 reduces galactose to galactitol TAS Mus musculus 4646 R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 4646 R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 4646 R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 4646 R-RNO-1630306 https://reactome.org/PathwayBrowser/#/R-RNO-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Rattus norvegicus 4646 R-RNO-2090079 https://reactome.org/PathwayBrowser/#/R-RNO-2090079 GLB1 hydrolyses linker chain(2) IEA Rattus norvegicus 4646 R-RNO-70355 https://reactome.org/PathwayBrowser/#/R-RNO-70355 GALK1 phosphorylates Gal to Gal1P IEA Rattus norvegicus 4646 R-RNO-9840795 https://reactome.org/PathwayBrowser/#/R-RNO-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Rattus norvegicus 4646 R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 4646 R-RNO-9931853 https://reactome.org/PathwayBrowser/#/R-RNO-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Rattus norvegicus 4646 R-SCE-9931853 https://reactome.org/PathwayBrowser/#/R-SCE-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Saccharomyces cerevisiae 4646 R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 4646 R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 4646 R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 4646 R-SSC-1630306 https://reactome.org/PathwayBrowser/#/R-SSC-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Sus scrofa 4646 R-SSC-2090079 https://reactome.org/PathwayBrowser/#/R-SSC-2090079 GLB1 hydrolyses linker chain(2) IEA Sus scrofa 4646 R-SSC-70355 https://reactome.org/PathwayBrowser/#/R-SSC-70355 GALK1 phosphorylates Gal to Gal1P IEA Sus scrofa 4646 R-SSC-9840795 https://reactome.org/PathwayBrowser/#/R-SSC-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Sus scrofa 4646 R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 4646 R-SSC-9931853 https://reactome.org/PathwayBrowser/#/R-SSC-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Sus scrofa 4646 R-XTR-1605624 https://reactome.org/PathwayBrowser/#/R-XTR-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Xenopus tropicalis 4646 R-XTR-1630306 https://reactome.org/PathwayBrowser/#/R-XTR-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Xenopus tropicalis 4646 R-XTR-2090079 https://reactome.org/PathwayBrowser/#/R-XTR-2090079 GLB1 hydrolyses linker chain(2) IEA Xenopus tropicalis 4646 R-XTR-70355 https://reactome.org/PathwayBrowser/#/R-XTR-70355 GALK1 phosphorylates Gal to Gal1P IEA Xenopus tropicalis 4646 R-XTR-9840795 https://reactome.org/PathwayBrowser/#/R-XTR-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Xenopus tropicalis 4646 R-XTR-9931853 https://reactome.org/PathwayBrowser/#/R-XTR-9931853 GALM converts beta-D-GAL to alpha-D-GAL IEA Xenopus tropicalis 4647 R-BTA-1855178 https://reactome.org/PathwayBrowser/#/R-BTA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Bos taurus 4647 R-CEL-1855178 https://reactome.org/PathwayBrowser/#/R-CEL-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Caenorhabditis elegans 4647 R-DDI-1855178 https://reactome.org/PathwayBrowser/#/R-DDI-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Dictyostelium discoideum 4647 R-DME-1855178 https://reactome.org/PathwayBrowser/#/R-DME-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Drosophila melanogaster 4647 R-GGA-1855178 https://reactome.org/PathwayBrowser/#/R-GGA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Gallus gallus 4647 R-HSA-1855178 https://reactome.org/PathwayBrowser/#/R-HSA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol TAS Homo sapiens 4647 R-MMU-1855178 https://reactome.org/PathwayBrowser/#/R-MMU-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Mus musculus 4647 R-PFA-1855178 https://reactome.org/PathwayBrowser/#/R-PFA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Plasmodium falciparum 4647 R-RNO-1855178 https://reactome.org/PathwayBrowser/#/R-RNO-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Rattus norvegicus 4647 R-SCE-1855178 https://reactome.org/PathwayBrowser/#/R-SCE-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Saccharomyces cerevisiae 4647 R-SSC-1855178 https://reactome.org/PathwayBrowser/#/R-SSC-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Sus scrofa 4647 R-XTR-1855178 https://reactome.org/PathwayBrowser/#/R-XTR-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Xenopus tropicalis 4650 R-BTA-2203480 https://reactome.org/PathwayBrowser/#/R-BTA-2203480 COLEC11 binds ligands IEA Bos taurus 4650 R-BTA-429567 https://reactome.org/PathwayBrowser/#/R-BTA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Bos taurus 4650 R-BTA-6799545 https://reactome.org/PathwayBrowser/#/R-BTA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Bos taurus 4650 R-BTA-6799581 https://reactome.org/PathwayBrowser/#/R-BTA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Bos taurus 4650 R-BTA-8853686 https://reactome.org/PathwayBrowser/#/R-BTA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Bos taurus 4650 R-BTA-8853710 https://reactome.org/PathwayBrowser/#/R-BTA-8853710 MANBA hydrolyses GlcNAc:Man IEA Bos taurus 4650 R-BTA-8876283 https://reactome.org/PathwayBrowser/#/R-BTA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Bos taurus 4650 R-BTA-964737 https://reactome.org/PathwayBrowser/#/R-BTA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 4650 R-BTA-964825 https://reactome.org/PathwayBrowser/#/R-BTA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 4650 R-BTA-964830 https://reactome.org/PathwayBrowser/#/R-BTA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Bos taurus 4650 R-BTA-975814 https://reactome.org/PathwayBrowser/#/R-BTA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Bos taurus 4650 R-BTA-9909159 https://reactome.org/PathwayBrowser/#/R-BTA-9909159 HK1 phosphorylates Mannose to Man6P IEA Bos taurus 4650 R-CEL-6799581 https://reactome.org/PathwayBrowser/#/R-CEL-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Caenorhabditis elegans 4650 R-CEL-8853686 https://reactome.org/PathwayBrowser/#/R-CEL-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Caenorhabditis elegans 4650 R-CEL-8853710 https://reactome.org/PathwayBrowser/#/R-CEL-8853710 MANBA hydrolyses GlcNAc:Man IEA Caenorhabditis elegans 4650 R-CEL-964737 https://reactome.org/PathwayBrowser/#/R-CEL-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 4650 R-CEL-964825 https://reactome.org/PathwayBrowser/#/R-CEL-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 4650 R-CEL-964830 https://reactome.org/PathwayBrowser/#/R-CEL-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Caenorhabditis elegans 4650 R-CEL-975814 https://reactome.org/PathwayBrowser/#/R-CEL-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Caenorhabditis elegans 4650 R-CEL-9909159 https://reactome.org/PathwayBrowser/#/R-CEL-9909159 HK1 phosphorylates Mannose to Man6P IEA Caenorhabditis elegans 4650 R-CFA-429567 https://reactome.org/PathwayBrowser/#/R-CFA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Canis familiaris 4650 R-CFA-6799545 https://reactome.org/PathwayBrowser/#/R-CFA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Canis familiaris 4650 R-CFA-8853686 https://reactome.org/PathwayBrowser/#/R-CFA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Canis familiaris 4650 R-CFA-8853710 https://reactome.org/PathwayBrowser/#/R-CFA-8853710 MANBA hydrolyses GlcNAc:Man IEA Canis familiaris 4650 R-CFA-8876283 https://reactome.org/PathwayBrowser/#/R-CFA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Canis familiaris 4650 R-CFA-964737 https://reactome.org/PathwayBrowser/#/R-CFA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 4650 R-CFA-964825 https://reactome.org/PathwayBrowser/#/R-CFA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 4650 R-CFA-964830 https://reactome.org/PathwayBrowser/#/R-CFA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Canis familiaris 4650 R-CFA-975814 https://reactome.org/PathwayBrowser/#/R-CFA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Canis familiaris 4650 R-CFA-9909159 https://reactome.org/PathwayBrowser/#/R-CFA-9909159 HK1 phosphorylates Mannose to Man6P IEA Canis familiaris 4650 R-DDI-6799545 https://reactome.org/PathwayBrowser/#/R-DDI-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Dictyostelium discoideum 4650 R-DDI-6799581 https://reactome.org/PathwayBrowser/#/R-DDI-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Dictyostelium discoideum 4650 R-DDI-8853686 https://reactome.org/PathwayBrowser/#/R-DDI-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Dictyostelium discoideum 4650 R-DDI-8853710 https://reactome.org/PathwayBrowser/#/R-DDI-8853710 MANBA hydrolyses GlcNAc:Man IEA Dictyostelium discoideum 4650 R-DDI-964737 https://reactome.org/PathwayBrowser/#/R-DDI-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 4650 R-DDI-964825 https://reactome.org/PathwayBrowser/#/R-DDI-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 4650 R-DDI-964830 https://reactome.org/PathwayBrowser/#/R-DDI-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Dictyostelium discoideum 4650 R-DME-6799581 https://reactome.org/PathwayBrowser/#/R-DME-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Drosophila melanogaster 4650 R-DME-8853686 https://reactome.org/PathwayBrowser/#/R-DME-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Drosophila melanogaster 4650 R-DME-8853710 https://reactome.org/PathwayBrowser/#/R-DME-8853710 MANBA hydrolyses GlcNAc:Man IEA Drosophila melanogaster 4650 R-DME-964737 https://reactome.org/PathwayBrowser/#/R-DME-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 4650 R-DME-964825 https://reactome.org/PathwayBrowser/#/R-DME-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 4650 R-DME-964830 https://reactome.org/PathwayBrowser/#/R-DME-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Drosophila melanogaster 4650 R-DME-975814 https://reactome.org/PathwayBrowser/#/R-DME-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Drosophila melanogaster 4650 R-DME-9909159 https://reactome.org/PathwayBrowser/#/R-DME-9909159 HK1 phosphorylates Mannose to Man6P IEA Drosophila melanogaster 4650 R-DRE-429567 https://reactome.org/PathwayBrowser/#/R-DRE-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Danio rerio 4650 R-DRE-8853710 https://reactome.org/PathwayBrowser/#/R-DRE-8853710 MANBA hydrolyses GlcNAc:Man IEA Danio rerio 4650 R-DRE-964737 https://reactome.org/PathwayBrowser/#/R-DRE-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 4650 R-DRE-964825 https://reactome.org/PathwayBrowser/#/R-DRE-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 4650 R-DRE-964830 https://reactome.org/PathwayBrowser/#/R-DRE-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Danio rerio 4650 R-DRE-9909159 https://reactome.org/PathwayBrowser/#/R-DRE-9909159 HK1 phosphorylates Mannose to Man6P IEA Danio rerio 4650 R-GGA-2203480 https://reactome.org/PathwayBrowser/#/R-GGA-2203480 COLEC11 binds ligands IEA Gallus gallus 4650 R-GGA-429567 https://reactome.org/PathwayBrowser/#/R-GGA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Gallus gallus 4650 R-GGA-6799545 https://reactome.org/PathwayBrowser/#/R-GGA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Gallus gallus 4650 R-GGA-6799581 https://reactome.org/PathwayBrowser/#/R-GGA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Gallus gallus 4650 R-GGA-8853710 https://reactome.org/PathwayBrowser/#/R-GGA-8853710 MANBA hydrolyses GlcNAc:Man IEA Gallus gallus 4650 R-GGA-8876283 https://reactome.org/PathwayBrowser/#/R-GGA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Gallus gallus 4650 R-GGA-964737 https://reactome.org/PathwayBrowser/#/R-GGA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 4650 R-GGA-964825 https://reactome.org/PathwayBrowser/#/R-GGA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 4650 R-GGA-964830 https://reactome.org/PathwayBrowser/#/R-GGA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Gallus gallus 4650 R-GGA-975814 https://reactome.org/PathwayBrowser/#/R-GGA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Gallus gallus 4650 R-GGA-9909159 https://reactome.org/PathwayBrowser/#/R-GGA-9909159 HK1 phosphorylates Mannose to Man6P IEA Gallus gallus 4650 R-HSA-2203480 https://reactome.org/PathwayBrowser/#/R-HSA-2203480 COLEC11 binds ligands TAS Homo sapiens 4650 R-HSA-429567 https://reactome.org/PathwayBrowser/#/R-HSA-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 TAS Homo sapiens 4650 R-HSA-6782685 https://reactome.org/PathwayBrowser/#/R-HSA-6782685 EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5 TAS Homo sapiens 4650 R-HSA-6799545 https://reactome.org/PathwayBrowser/#/R-HSA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 TAS Homo sapiens 4650 R-HSA-6799581 https://reactome.org/PathwayBrowser/#/R-HSA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man TAS Homo sapiens 4650 R-HSA-8853686 https://reactome.org/PathwayBrowser/#/R-HSA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 TAS Homo sapiens 4650 R-HSA-8853710 https://reactome.org/PathwayBrowser/#/R-HSA-8853710 MANBA hydrolyses GlcNAc:Man TAS Homo sapiens 4650 R-HSA-8876283 https://reactome.org/PathwayBrowser/#/R-HSA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol TAS Homo sapiens 4650 R-HSA-901024 https://reactome.org/PathwayBrowser/#/R-HSA-901024 MAN1B1 hydrolyses 1,2-linked mannose (a branch) TAS Homo sapiens 4650 R-HSA-901036 https://reactome.org/PathwayBrowser/#/R-HSA-901036 MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) TAS Homo sapiens 4650 R-HSA-901039 https://reactome.org/PathwayBrowser/#/R-HSA-901039 MAN1B1 hydrolyses 1,2-linked mannose (c branch) TAS Homo sapiens 4650 R-HSA-901074 https://reactome.org/PathwayBrowser/#/R-HSA-901074 MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 4650 R-HSA-964737 https://reactome.org/PathwayBrowser/#/R-HSA-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 4650 R-HSA-964825 https://reactome.org/PathwayBrowser/#/R-HSA-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 4650 R-HSA-964830 https://reactome.org/PathwayBrowser/#/R-HSA-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 TAS Homo sapiens 4650 R-HSA-975814 https://reactome.org/PathwayBrowser/#/R-HSA-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 TAS Homo sapiens 4650 R-HSA-9909159 https://reactome.org/PathwayBrowser/#/R-HSA-9909159 HK1 phosphorylates Mannose to Man6P TAS Homo sapiens 4650 R-MMU-2203480 https://reactome.org/PathwayBrowser/#/R-MMU-2203480 COLEC11 binds ligands IEA Mus musculus 4650 R-MMU-429567 https://reactome.org/PathwayBrowser/#/R-MMU-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Mus musculus 4650 R-MMU-6799545 https://reactome.org/PathwayBrowser/#/R-MMU-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Mus musculus 4650 R-MMU-6799581 https://reactome.org/PathwayBrowser/#/R-MMU-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Mus musculus 4650 R-MMU-8853686 https://reactome.org/PathwayBrowser/#/R-MMU-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Mus musculus 4650 R-MMU-8853710 https://reactome.org/PathwayBrowser/#/R-MMU-8853710 MANBA hydrolyses GlcNAc:Man IEA Mus musculus 4650 R-MMU-8876283 https://reactome.org/PathwayBrowser/#/R-MMU-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Mus musculus 4650 R-MMU-964737 https://reactome.org/PathwayBrowser/#/R-MMU-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 4650 R-MMU-964825 https://reactome.org/PathwayBrowser/#/R-MMU-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 4650 R-MMU-964830 https://reactome.org/PathwayBrowser/#/R-MMU-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Mus musculus 4650 R-MMU-975814 https://reactome.org/PathwayBrowser/#/R-MMU-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Mus musculus 4650 R-MMU-9909159 https://reactome.org/PathwayBrowser/#/R-MMU-9909159 HK1 phosphorylates Mannose to Man6P IEA Mus musculus 4650 R-PFA-9909159 https://reactome.org/PathwayBrowser/#/R-PFA-9909159 HK1 phosphorylates Mannose to Man6P IEA Plasmodium falciparum 4650 R-RNO-429567 https://reactome.org/PathwayBrowser/#/R-RNO-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Rattus norvegicus 4650 R-RNO-6799545 https://reactome.org/PathwayBrowser/#/R-RNO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Rattus norvegicus 4650 R-RNO-6799581 https://reactome.org/PathwayBrowser/#/R-RNO-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Rattus norvegicus 4650 R-RNO-8853686 https://reactome.org/PathwayBrowser/#/R-RNO-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Rattus norvegicus 4650 R-RNO-8853710 https://reactome.org/PathwayBrowser/#/R-RNO-8853710 MANBA hydrolyses GlcNAc:Man IEA Rattus norvegicus 4650 R-RNO-8876283 https://reactome.org/PathwayBrowser/#/R-RNO-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Rattus norvegicus 4650 R-RNO-964737 https://reactome.org/PathwayBrowser/#/R-RNO-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 4650 R-RNO-964825 https://reactome.org/PathwayBrowser/#/R-RNO-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 4650 R-RNO-964830 https://reactome.org/PathwayBrowser/#/R-RNO-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Rattus norvegicus 4650 R-RNO-975814 https://reactome.org/PathwayBrowser/#/R-RNO-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Rattus norvegicus 4650 R-RNO-9909159 https://reactome.org/PathwayBrowser/#/R-RNO-9909159 HK1 phosphorylates Mannose to Man6P IEA Rattus norvegicus 4650 R-SCE-6799545 https://reactome.org/PathwayBrowser/#/R-SCE-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Saccharomyces cerevisiae 4650 R-SCE-9909159 https://reactome.org/PathwayBrowser/#/R-SCE-9909159 HK1 phosphorylates Mannose to Man6P IEA Saccharomyces cerevisiae 4650 R-SPO-6799545 https://reactome.org/PathwayBrowser/#/R-SPO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Schizosaccharomyces pombe 4650 R-SPO-9909159 https://reactome.org/PathwayBrowser/#/R-SPO-9909159 HK1 phosphorylates Mannose to Man6P IEA Schizosaccharomyces pombe 4650 R-SSC-2203480 https://reactome.org/PathwayBrowser/#/R-SSC-2203480 COLEC11 binds ligands IEA Sus scrofa 4650 R-SSC-429567 https://reactome.org/PathwayBrowser/#/R-SSC-429567 Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 IEA Sus scrofa 4650 R-SSC-6799545 https://reactome.org/PathwayBrowser/#/R-SSC-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Sus scrofa 4650 R-SSC-6799581 https://reactome.org/PathwayBrowser/#/R-SSC-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Sus scrofa 4650 R-SSC-8853686 https://reactome.org/PathwayBrowser/#/R-SSC-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Sus scrofa 4650 R-SSC-8853710 https://reactome.org/PathwayBrowser/#/R-SSC-8853710 MANBA hydrolyses GlcNAc:Man IEA Sus scrofa 4650 R-SSC-8876283 https://reactome.org/PathwayBrowser/#/R-SSC-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Sus scrofa 4650 R-SSC-964737 https://reactome.org/PathwayBrowser/#/R-SSC-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 4650 R-SSC-964825 https://reactome.org/PathwayBrowser/#/R-SSC-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 4650 R-SSC-964830 https://reactome.org/PathwayBrowser/#/R-SSC-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Sus scrofa 4650 R-SSC-975814 https://reactome.org/PathwayBrowser/#/R-SSC-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Sus scrofa 4650 R-SSC-9909159 https://reactome.org/PathwayBrowser/#/R-SSC-9909159 HK1 phosphorylates Mannose to Man6P IEA Sus scrofa 4650 R-XTR-6799545 https://reactome.org/PathwayBrowser/#/R-XTR-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Xenopus tropicalis 4650 R-XTR-6799581 https://reactome.org/PathwayBrowser/#/R-XTR-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Xenopus tropicalis 4650 R-XTR-8853686 https://reactome.org/PathwayBrowser/#/R-XTR-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Xenopus tropicalis 4650 R-XTR-8853710 https://reactome.org/PathwayBrowser/#/R-XTR-8853710 MANBA hydrolyses GlcNAc:Man IEA Xenopus tropicalis 4650 R-XTR-8876283 https://reactome.org/PathwayBrowser/#/R-XTR-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Xenopus tropicalis 4650 R-XTR-964737 https://reactome.org/PathwayBrowser/#/R-XTR-964737 Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 4650 R-XTR-964825 https://reactome.org/PathwayBrowser/#/R-XTR-964825 Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 4650 R-XTR-964830 https://reactome.org/PathwayBrowser/#/R-XTR-964830 Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 IEA Xenopus tropicalis 4650 R-XTR-975814 https://reactome.org/PathwayBrowser/#/R-XTR-975814 Trimming of mannoses on the alpha1,6 arm by MAN2A1 IEA Xenopus tropicalis 4650 R-XTR-9909159 https://reactome.org/PathwayBrowser/#/R-XTR-9909159 HK1 phosphorylates Mannose to Man6P IEA Xenopus tropicalis 4654 R-BTA-189069 https://reactome.org/PathwayBrowser/#/R-BTA-189069 sucrose + H2O => glucose + fructose IEA Bos taurus 4654 R-BTA-189222 https://reactome.org/PathwayBrowser/#/R-BTA-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Bos taurus 4654 R-BTA-189242 https://reactome.org/PathwayBrowser/#/R-BTA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Bos taurus 4654 R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 4654 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 4654 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 4654 R-BTA-428779 https://reactome.org/PathwayBrowser/#/R-BTA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Bos taurus 4654 R-BTA-429036 https://reactome.org/PathwayBrowser/#/R-BTA-429036 SLC2A9 transports Fru, Glc, urate IEA Bos taurus 4654 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 4654 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 4654 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 4654 R-BTA-8876283 https://reactome.org/PathwayBrowser/#/R-BTA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Bos taurus 4654 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 4654 R-CEL-189069 https://reactome.org/PathwayBrowser/#/R-CEL-189069 sucrose + H2O => glucose + fructose IEA Caenorhabditis elegans 4654 R-CEL-189222 https://reactome.org/PathwayBrowser/#/R-CEL-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Caenorhabditis elegans 4654 R-CEL-189242 https://reactome.org/PathwayBrowser/#/R-CEL-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Caenorhabditis elegans 4654 R-CEL-428779 https://reactome.org/PathwayBrowser/#/R-CEL-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Caenorhabditis elegans 4654 R-CEL-429036 https://reactome.org/PathwayBrowser/#/R-CEL-429036 SLC2A9 transports Fru, Glc, urate IEA Caenorhabditis elegans 4654 R-CFA-189069 https://reactome.org/PathwayBrowser/#/R-CFA-189069 sucrose + H2O => glucose + fructose IEA Canis familiaris 4654 R-CFA-189222 https://reactome.org/PathwayBrowser/#/R-CFA-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Canis familiaris 4654 R-CFA-189242 https://reactome.org/PathwayBrowser/#/R-CFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Canis familiaris 4654 R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 4654 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 4654 R-CFA-428779 https://reactome.org/PathwayBrowser/#/R-CFA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Canis familiaris 4654 R-CFA-429036 https://reactome.org/PathwayBrowser/#/R-CFA-429036 SLC2A9 transports Fru, Glc, urate IEA Canis familiaris 4654 R-CFA-8876283 https://reactome.org/PathwayBrowser/#/R-CFA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Canis familiaris 4654 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 4654 R-DDI-189069 https://reactome.org/PathwayBrowser/#/R-DDI-189069 sucrose + H2O => glucose + fructose IEA Dictyostelium discoideum 4654 R-DDI-189222 https://reactome.org/PathwayBrowser/#/R-DDI-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Dictyostelium discoideum 4654 R-DDI-189242 https://reactome.org/PathwayBrowser/#/R-DDI-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Dictyostelium discoideum 4654 R-DDI-428779 https://reactome.org/PathwayBrowser/#/R-DDI-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Dictyostelium discoideum 4654 R-DDI-429036 https://reactome.org/PathwayBrowser/#/R-DDI-429036 SLC2A9 transports Fru, Glc, urate IEA Dictyostelium discoideum 4654 R-DME-189222 https://reactome.org/PathwayBrowser/#/R-DME-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Drosophila melanogaster 4654 R-DME-189242 https://reactome.org/PathwayBrowser/#/R-DME-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Drosophila melanogaster 4654 R-DME-428779 https://reactome.org/PathwayBrowser/#/R-DME-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Drosophila melanogaster 4654 R-DME-429036 https://reactome.org/PathwayBrowser/#/R-DME-429036 SLC2A9 transports Fru, Glc, urate IEA Drosophila melanogaster 4654 R-DRE-189242 https://reactome.org/PathwayBrowser/#/R-DRE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Danio rerio 4654 R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 4654 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 4654 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 4654 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 4654 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 4654 R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus 4654 R-GGA-189222 https://reactome.org/PathwayBrowser/#/R-GGA-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Gallus gallus 4654 R-GGA-189242 https://reactome.org/PathwayBrowser/#/R-GGA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Gallus gallus 4654 R-GGA-428779 https://reactome.org/PathwayBrowser/#/R-GGA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Gallus gallus 4654 R-GGA-429036 https://reactome.org/PathwayBrowser/#/R-GGA-429036 SLC2A9 transports Fru, Glc, urate IEA Gallus gallus 4654 R-GGA-8876283 https://reactome.org/PathwayBrowser/#/R-GGA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Gallus gallus 4654 R-HSA-189069 https://reactome.org/PathwayBrowser/#/R-HSA-189069 sucrose + H2O => glucose + fructose TAS Homo sapiens 4654 R-HSA-189222 https://reactome.org/PathwayBrowser/#/R-HSA-189222 SLC2A5 transports fructose from extracellular region to cytosol TAS Homo sapiens 4654 R-HSA-189242 https://reactome.org/PathwayBrowser/#/R-HSA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 4654 R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 4654 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 4654 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 4654 R-HSA-428779 https://reactome.org/PathwayBrowser/#/R-HSA-428779 GLUT7 and GLUT11 transport glucose and fructose TAS Homo sapiens 4654 R-HSA-429036 https://reactome.org/PathwayBrowser/#/R-HSA-429036 SLC2A9 transports Fru, Glc, urate TAS Homo sapiens 4654 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 4654 R-HSA-5638209 https://reactome.org/PathwayBrowser/#/R-HSA-5638209 Defective SLC2A9 does not transport Fru, Glc, urate TAS Homo sapiens 4654 R-HSA-5638222 https://reactome.org/PathwayBrowser/#/R-HSA-5638222 Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region TAS Homo sapiens 4654 R-HSA-5656459 https://reactome.org/PathwayBrowser/#/R-HSA-5656459 Defective KHK does not phosphorylate beta-D-fructose TAS Homo sapiens 4654 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 4654 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 4654 R-HSA-8876283 https://reactome.org/PathwayBrowser/#/R-HSA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol TAS Homo sapiens 4654 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 4654 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 4654 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 4654 R-MMU-189069 https://reactome.org/PathwayBrowser/#/R-MMU-189069 sucrose + H2O => glucose + fructose IEA Mus musculus 4654 R-MMU-189222 https://reactome.org/PathwayBrowser/#/R-MMU-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Mus musculus 4654 R-MMU-189242 https://reactome.org/PathwayBrowser/#/R-MMU-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Mus musculus 4654 R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 4654 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 4654 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 4654 R-MMU-428779 https://reactome.org/PathwayBrowser/#/R-MMU-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Mus musculus 4654 R-MMU-429036 https://reactome.org/PathwayBrowser/#/R-MMU-429036 SLC2A9 transports Fru, Glc, urate IEA Mus musculus 4654 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 4654 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 4654 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 4654 R-MMU-8876283 https://reactome.org/PathwayBrowser/#/R-MMU-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Mus musculus 4654 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 4654 R-PFA-189222 https://reactome.org/PathwayBrowser/#/R-PFA-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Plasmodium falciparum 4654 R-PFA-189242 https://reactome.org/PathwayBrowser/#/R-PFA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Plasmodium falciparum 4654 R-PFA-428779 https://reactome.org/PathwayBrowser/#/R-PFA-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Plasmodium falciparum 4654 R-PFA-429036 https://reactome.org/PathwayBrowser/#/R-PFA-429036 SLC2A9 transports Fru, Glc, urate IEA Plasmodium falciparum 4654 R-RNO-189069 https://reactome.org/PathwayBrowser/#/R-RNO-189069 sucrose + H2O => glucose + fructose IEA Rattus norvegicus 4654 R-RNO-189222 https://reactome.org/PathwayBrowser/#/R-RNO-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Rattus norvegicus 4654 R-RNO-189242 https://reactome.org/PathwayBrowser/#/R-RNO-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Rattus norvegicus 4654 R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 4654 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 4654 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 4654 R-RNO-428779 https://reactome.org/PathwayBrowser/#/R-RNO-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Rattus norvegicus 4654 R-RNO-429036 https://reactome.org/PathwayBrowser/#/R-RNO-429036 SLC2A9 transports Fru, Glc, urate IEA Rattus norvegicus 4654 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 4654 R-RNO-8876283 https://reactome.org/PathwayBrowser/#/R-RNO-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Rattus norvegicus 4654 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 4654 R-SCE-189222 https://reactome.org/PathwayBrowser/#/R-SCE-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Saccharomyces cerevisiae 4654 R-SCE-189242 https://reactome.org/PathwayBrowser/#/R-SCE-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Saccharomyces cerevisiae 4654 R-SCE-428779 https://reactome.org/PathwayBrowser/#/R-SCE-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Saccharomyces cerevisiae 4654 R-SCE-429036 https://reactome.org/PathwayBrowser/#/R-SCE-429036 SLC2A9 transports Fru, Glc, urate IEA Saccharomyces cerevisiae 4654 R-SPO-189069 https://reactome.org/PathwayBrowser/#/R-SPO-189069 sucrose + H2O => glucose + fructose IEA Schizosaccharomyces pombe 4654 R-SSC-189069 https://reactome.org/PathwayBrowser/#/R-SSC-189069 sucrose + H2O => glucose + fructose IEA Sus scrofa 4654 R-SSC-189222 https://reactome.org/PathwayBrowser/#/R-SSC-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Sus scrofa 4654 R-SSC-189242 https://reactome.org/PathwayBrowser/#/R-SSC-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Sus scrofa 4654 R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 4654 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 4654 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 4654 R-SSC-428779 https://reactome.org/PathwayBrowser/#/R-SSC-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Sus scrofa 4654 R-SSC-429036 https://reactome.org/PathwayBrowser/#/R-SSC-429036 SLC2A9 transports Fru, Glc, urate IEA Sus scrofa 4654 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 4654 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 4654 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 4654 R-SSC-8876283 https://reactome.org/PathwayBrowser/#/R-SSC-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Sus scrofa 4654 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 4654 R-XTR-189222 https://reactome.org/PathwayBrowser/#/R-XTR-189222 SLC2A5 transports fructose from extracellular region to cytosol IEA Xenopus tropicalis 4654 R-XTR-189242 https://reactome.org/PathwayBrowser/#/R-XTR-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region IEA Xenopus tropicalis 4654 R-XTR-428779 https://reactome.org/PathwayBrowser/#/R-XTR-428779 GLUT7 and GLUT11 transport glucose and fructose IEA Xenopus tropicalis 4654 R-XTR-429036 https://reactome.org/PathwayBrowser/#/R-XTR-429036 SLC2A9 transports Fru, Glc, urate IEA Xenopus tropicalis 4654 R-XTR-8876283 https://reactome.org/PathwayBrowser/#/R-XTR-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol IEA Xenopus tropicalis 4678 R-BTA-376200 https://reactome.org/PathwayBrowser/#/R-BTA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Bos taurus 4678 R-CFA-376200 https://reactome.org/PathwayBrowser/#/R-CFA-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Canis familiaris 4678 R-DME-376200 https://reactome.org/PathwayBrowser/#/R-DME-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Drosophila melanogaster 4678 R-HSA-376200 https://reactome.org/PathwayBrowser/#/R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids TAS Homo sapiens 4678 R-MMU-376200 https://reactome.org/PathwayBrowser/#/R-MMU-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Mus musculus 4678 R-RNO-376200 https://reactome.org/PathwayBrowser/#/R-RNO-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Rattus norvegicus 4678 R-SSC-376200 https://reactome.org/PathwayBrowser/#/R-SSC-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Sus scrofa 4678 R-XTR-376200 https://reactome.org/PathwayBrowser/#/R-XTR-376200 SLC7A10-mediated uptake of small neutral amino acids IEA Xenopus tropicalis 47 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 47 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 47 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 47 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 47 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 47 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 47 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 47 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 47 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 47 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 47 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 47 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 47 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 47 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 47 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 47 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 47 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 47 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 47 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 47 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 47 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 47 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 47 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 47 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 47 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 47 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 47 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 47 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 4709 R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Bos taurus 4709 R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Caenorhabditis elegans 4709 R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Canis familiaris 4709 R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Dictyostelium discoideum 4709 R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Drosophila melanogaster 4709 R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Danio rerio 4709 R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Gallus gallus 4709 R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA TAS Homo sapiens 4709 R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Mus musculus 4709 R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Rattus norvegicus 4709 R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Saccharomyces cerevisiae 4709 R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Schizosaccharomyces pombe 4709 R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Sus scrofa 4709 R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Xenopus tropicalis 4710 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 4710 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 4710 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 4710 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 4710 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 4710 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 4710 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 4710 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 4710 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 4710 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 4710 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 4710 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 4710 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 4710 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 4710 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 4710 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 4710 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 4710 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 4710 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 4710 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 4710 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 4710 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 4710 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 4710 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 4710 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 4710 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 4710 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 4710 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 4710 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 4710 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 4710 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 4710 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 4710 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 4710 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 4710 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 4718 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 4718 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 4718 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 4718 R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 4718 R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 4718 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4718 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4718 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 4718 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4718 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4718 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 4718 R-BTA-109759 https://reactome.org/PathwayBrowser/#/R-BTA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Bos taurus 4718 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 4718 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 4718 R-BTA-73632 https://reactome.org/PathwayBrowser/#/R-BTA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Bos taurus 4718 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 4718 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4718 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4718 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 4718 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4718 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4718 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 4718 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 4718 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 4718 R-CEL-73632 https://reactome.org/PathwayBrowser/#/R-CEL-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Caenorhabditis elegans 4718 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 4718 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 4718 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 4718 R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 4718 R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 4718 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4718 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4718 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4718 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4718 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 4718 R-CFA-109759 https://reactome.org/PathwayBrowser/#/R-CFA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Canis familiaris 4718 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 4718 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 4718 R-CFA-73632 https://reactome.org/PathwayBrowser/#/R-CFA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Canis familiaris 4718 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4718 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4718 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4718 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4718 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 4718 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 4718 R-DDI-73632 https://reactome.org/PathwayBrowser/#/R-DDI-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Dictyostelium discoideum 4718 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 4718 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 4718 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4718 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4718 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 4718 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4718 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4718 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 4718 R-DME-109759 https://reactome.org/PathwayBrowser/#/R-DME-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Drosophila melanogaster 4718 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 4718 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 4718 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 4718 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 4718 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 4718 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4718 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4718 R-DRE-73632 https://reactome.org/PathwayBrowser/#/R-DRE-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Danio rerio 4718 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 4718 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 4718 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 4718 R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 4718 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 4718 R-GGA-109759 https://reactome.org/PathwayBrowser/#/R-GGA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Gallus gallus 4718 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 4718 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 4718 R-GGA-73632 https://reactome.org/PathwayBrowser/#/R-GGA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Gallus gallus 4718 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 4718 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 4718 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 4718 R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 4718 R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 4718 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4718 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4718 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 4718 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4718 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4718 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 4718 R-HSA-109759 https://reactome.org/PathwayBrowser/#/R-HSA-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] TAS Homo sapiens 4718 R-HSA-112265 https://reactome.org/PathwayBrowser/#/R-HSA-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] TAS Homo sapiens 4718 R-HSA-112266 https://reactome.org/PathwayBrowser/#/R-HSA-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] TAS Homo sapiens 4718 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4718 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4718 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 4718 R-HSA-73632 https://reactome.org/PathwayBrowser/#/R-HSA-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] TAS Homo sapiens 4718 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 4718 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 4718 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 4718 R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 4718 R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 4718 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4718 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4718 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 4718 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4718 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4718 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 4718 R-MMU-109759 https://reactome.org/PathwayBrowser/#/R-MMU-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Mus musculus 4718 R-MMU-112265 https://reactome.org/PathwayBrowser/#/R-MMU-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Mus musculus 4718 R-MMU-112266 https://reactome.org/PathwayBrowser/#/R-MMU-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Mus musculus 4718 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 4718 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 4718 R-MMU-73632 https://reactome.org/PathwayBrowser/#/R-MMU-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Mus musculus 4718 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4718 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4718 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4718 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4718 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 4718 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 4718 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 4718 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 4718 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 4718 R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 4718 R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 4718 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4718 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4718 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 4718 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4718 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4718 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 4718 R-RNO-109759 https://reactome.org/PathwayBrowser/#/R-RNO-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Rattus norvegicus 4718 R-RNO-112265 https://reactome.org/PathwayBrowser/#/R-RNO-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Rattus norvegicus 4718 R-RNO-112266 https://reactome.org/PathwayBrowser/#/R-RNO-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Rattus norvegicus 4718 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 4718 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 4718 R-RNO-73632 https://reactome.org/PathwayBrowser/#/R-RNO-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Rattus norvegicus 4718 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 4718 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 4718 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 4718 R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 4718 R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 4718 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4718 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4718 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 4718 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4718 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4718 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 4718 R-SSC-109759 https://reactome.org/PathwayBrowser/#/R-SSC-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Sus scrofa 4718 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 4718 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 4718 R-SSC-73632 https://reactome.org/PathwayBrowser/#/R-SSC-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Sus scrofa 4718 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 4718 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 4718 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 4718 R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 4718 R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 4718 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 4718 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4718 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4718 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 4718 R-XTR-109759 https://reactome.org/PathwayBrowser/#/R-XTR-109759 deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] IEA Xenopus tropicalis 4718 R-XTR-112265 https://reactome.org/PathwayBrowser/#/R-XTR-112265 thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] IEA Xenopus tropicalis 4718 R-XTR-112266 https://reactome.org/PathwayBrowser/#/R-XTR-112266 thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] IEA Xenopus tropicalis 4718 R-XTR-73632 https://reactome.org/PathwayBrowser/#/R-XTR-73632 thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] IEA Xenopus tropicalis 4724 R-BTA-2090079 https://reactome.org/PathwayBrowser/#/R-BTA-2090079 GLB1 hydrolyses linker chain(2) IEA Bos taurus 4724 R-CEL-2090079 https://reactome.org/PathwayBrowser/#/R-CEL-2090079 GLB1 hydrolyses linker chain(2) IEA Caenorhabditis elegans 4724 R-CFA-2090079 https://reactome.org/PathwayBrowser/#/R-CFA-2090079 GLB1 hydrolyses linker chain(2) IEA Canis familiaris 4724 R-DDI-2090079 https://reactome.org/PathwayBrowser/#/R-DDI-2090079 GLB1 hydrolyses linker chain(2) IEA Dictyostelium discoideum 4724 R-DME-2090079 https://reactome.org/PathwayBrowser/#/R-DME-2090079 GLB1 hydrolyses linker chain(2) IEA Drosophila melanogaster 4724 R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus 4724 R-HSA-2090079 https://reactome.org/PathwayBrowser/#/R-HSA-2090079 GLB1 hydrolyses linker chain(2) TAS Homo sapiens 4724 R-MMU-2090079 https://reactome.org/PathwayBrowser/#/R-MMU-2090079 GLB1 hydrolyses linker chain(2) IEA Mus musculus 4724 R-RNO-2090079 https://reactome.org/PathwayBrowser/#/R-RNO-2090079 GLB1 hydrolyses linker chain(2) IEA Rattus norvegicus 4724 R-SSC-2090079 https://reactome.org/PathwayBrowser/#/R-SSC-2090079 GLB1 hydrolyses linker chain(2) IEA Sus scrofa 4724 R-XTR-2090079 https://reactome.org/PathwayBrowser/#/R-XTR-2090079 GLB1 hydrolyses linker chain(2) IEA Xenopus tropicalis 4726 R-BTA-879594 https://reactome.org/PathwayBrowser/#/R-BTA-879594 SLCO4C1 mediates the transport of digoxin IEA Bos taurus 4726 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 4726 R-BTA-9684068 https://reactome.org/PathwayBrowser/#/R-BTA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Bos taurus 4726 R-CEL-879594 https://reactome.org/PathwayBrowser/#/R-CEL-879594 SLCO4C1 mediates the transport of digoxin IEA Caenorhabditis elegans 4726 R-CFA-879594 https://reactome.org/PathwayBrowser/#/R-CFA-879594 SLCO4C1 mediates the transport of digoxin IEA Canis familiaris 4726 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 4726 R-CFA-9684068 https://reactome.org/PathwayBrowser/#/R-CFA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Canis familiaris 4726 R-DME-879594 https://reactome.org/PathwayBrowser/#/R-DME-879594 SLCO4C1 mediates the transport of digoxin IEA Drosophila melanogaster 4726 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 4726 R-DRE-9684068 https://reactome.org/PathwayBrowser/#/R-DRE-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Danio rerio 4726 R-GGA-879594 https://reactome.org/PathwayBrowser/#/R-GGA-879594 SLCO4C1 mediates the transport of digoxin IEA Gallus gallus 4726 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 4726 R-GGA-9684068 https://reactome.org/PathwayBrowser/#/R-GGA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Gallus gallus 4726 R-HSA-879594 https://reactome.org/PathwayBrowser/#/R-HSA-879594 SLCO4C1 mediates the transport of digoxin TAS Homo sapiens 4726 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 4726 R-HSA-9684068 https://reactome.org/PathwayBrowser/#/R-HSA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides TAS Homo sapiens 4726 R-MMU-879594 https://reactome.org/PathwayBrowser/#/R-MMU-879594 SLCO4C1 mediates the transport of digoxin IEA Mus musculus 4726 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 4726 R-MMU-9684068 https://reactome.org/PathwayBrowser/#/R-MMU-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Mus musculus 4726 R-RNO-879594 https://reactome.org/PathwayBrowser/#/R-RNO-879594 SLCO4C1 mediates the transport of digoxin IEA Rattus norvegicus 4726 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 4726 R-RNO-9684068 https://reactome.org/PathwayBrowser/#/R-RNO-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Rattus norvegicus 4726 R-SSC-879594 https://reactome.org/PathwayBrowser/#/R-SSC-879594 SLCO4C1 mediates the transport of digoxin IEA Sus scrofa 4726 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 4726 R-SSC-9684068 https://reactome.org/PathwayBrowser/#/R-SSC-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Sus scrofa 4726 R-XTR-879594 https://reactome.org/PathwayBrowser/#/R-XTR-879594 SLCO4C1 mediates the transport of digoxin IEA Xenopus tropicalis 4726 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 4726 R-XTR-9684068 https://reactome.org/PathwayBrowser/#/R-XTR-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Xenopus tropicalis 4728 R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 4728 R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 4728 R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 4728 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4728 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4728 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 4728 R-BTA-109534 https://reactome.org/PathwayBrowser/#/R-BTA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4728 R-BTA-109536 https://reactome.org/PathwayBrowser/#/R-BTA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Bos taurus 4728 R-BTA-109538 https://reactome.org/PathwayBrowser/#/R-BTA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Bos taurus 4728 R-BTA-109903 https://reactome.org/PathwayBrowser/#/R-BTA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Bos taurus 4728 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 4728 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 4728 R-BTA-73598 https://reactome.org/PathwayBrowser/#/R-BTA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Bos taurus 4728 R-BTA-73599 https://reactome.org/PathwayBrowser/#/R-BTA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Bos taurus 4728 R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 4728 R-BTA-8954327 https://reactome.org/PathwayBrowser/#/R-BTA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Bos taurus 4728 R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 4728 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4728 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4728 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 4728 R-CEL-109534 https://reactome.org/PathwayBrowser/#/R-CEL-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4728 R-CEL-109536 https://reactome.org/PathwayBrowser/#/R-CEL-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Caenorhabditis elegans 4728 R-CEL-109538 https://reactome.org/PathwayBrowser/#/R-CEL-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Caenorhabditis elegans 4728 R-CEL-109903 https://reactome.org/PathwayBrowser/#/R-CEL-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Caenorhabditis elegans 4728 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 4728 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 4728 R-CEL-73599 https://reactome.org/PathwayBrowser/#/R-CEL-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Caenorhabditis elegans 4728 R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 4728 R-CEL-8954327 https://reactome.org/PathwayBrowser/#/R-CEL-8954327 UCKL1 phosphorylates urindine, cytidine IEA Caenorhabditis elegans 4728 R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 4728 R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 4728 R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 4728 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4728 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4728 R-CFA-109534 https://reactome.org/PathwayBrowser/#/R-CFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4728 R-CFA-109536 https://reactome.org/PathwayBrowser/#/R-CFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Canis familiaris 4728 R-CFA-109538 https://reactome.org/PathwayBrowser/#/R-CFA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Canis familiaris 4728 R-CFA-109903 https://reactome.org/PathwayBrowser/#/R-CFA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Canis familiaris 4728 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 4728 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 4728 R-CFA-73598 https://reactome.org/PathwayBrowser/#/R-CFA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Canis familiaris 4728 R-CFA-73599 https://reactome.org/PathwayBrowser/#/R-CFA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Canis familiaris 4728 R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 4728 R-CFA-8954327 https://reactome.org/PathwayBrowser/#/R-CFA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Canis familiaris 4728 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4728 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4728 R-DDI-109534 https://reactome.org/PathwayBrowser/#/R-DDI-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4728 R-DDI-109536 https://reactome.org/PathwayBrowser/#/R-DDI-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Dictyostelium discoideum 4728 R-DDI-109903 https://reactome.org/PathwayBrowser/#/R-DDI-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Dictyostelium discoideum 4728 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 4728 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 4728 R-DDI-73599 https://reactome.org/PathwayBrowser/#/R-DDI-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Dictyostelium discoideum 4728 R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 4728 R-DDI-8954327 https://reactome.org/PathwayBrowser/#/R-DDI-8954327 UCKL1 phosphorylates urindine, cytidine IEA Dictyostelium discoideum 4728 R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 4728 R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 4728 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4728 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4728 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 4728 R-DME-109534 https://reactome.org/PathwayBrowser/#/R-DME-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4728 R-DME-109536 https://reactome.org/PathwayBrowser/#/R-DME-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Drosophila melanogaster 4728 R-DME-109538 https://reactome.org/PathwayBrowser/#/R-DME-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Drosophila melanogaster 4728 R-DME-109903 https://reactome.org/PathwayBrowser/#/R-DME-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Drosophila melanogaster 4728 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 4728 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 4728 R-DME-73599 https://reactome.org/PathwayBrowser/#/R-DME-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Drosophila melanogaster 4728 R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 4728 R-DME-8954327 https://reactome.org/PathwayBrowser/#/R-DME-8954327 UCKL1 phosphorylates urindine, cytidine IEA Drosophila melanogaster 4728 R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 4728 R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 4728 R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 4728 R-DRE-109534 https://reactome.org/PathwayBrowser/#/R-DRE-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4728 R-DRE-109536 https://reactome.org/PathwayBrowser/#/R-DRE-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Danio rerio 4728 R-DRE-109903 https://reactome.org/PathwayBrowser/#/R-DRE-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Danio rerio 4728 R-DRE-73598 https://reactome.org/PathwayBrowser/#/R-DRE-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Danio rerio 4728 R-DRE-73599 https://reactome.org/PathwayBrowser/#/R-DRE-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Danio rerio 4728 R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 4728 R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 4728 R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 4728 R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 4728 R-GGA-109538 https://reactome.org/PathwayBrowser/#/R-GGA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Gallus gallus 4728 R-GGA-109903 https://reactome.org/PathwayBrowser/#/R-GGA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Gallus gallus 4728 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 4728 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 4728 R-GGA-73598 https://reactome.org/PathwayBrowser/#/R-GGA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Gallus gallus 4728 R-GGA-73599 https://reactome.org/PathwayBrowser/#/R-GGA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Gallus gallus 4728 R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 4728 R-GGA-8954327 https://reactome.org/PathwayBrowser/#/R-GGA-8954327 UCKL1 phosphorylates urindine, cytidine IEA Gallus gallus 4728 R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 4728 R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 4728 R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 4728 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4728 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4728 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 4728 R-HSA-109534 https://reactome.org/PathwayBrowser/#/R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4728 R-HSA-109536 https://reactome.org/PathwayBrowser/#/R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 TAS Homo sapiens 4728 R-HSA-109538 https://reactome.org/PathwayBrowser/#/R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 TAS Homo sapiens 4728 R-HSA-109903 https://reactome.org/PathwayBrowser/#/R-HSA-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] TAS Homo sapiens 4728 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4728 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4728 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 4728 R-HSA-73598 https://reactome.org/PathwayBrowser/#/R-HSA-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) TAS Homo sapiens 4728 R-HSA-73599 https://reactome.org/PathwayBrowser/#/R-HSA-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] TAS Homo sapiens 4728 R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 4728 R-HSA-8954327 https://reactome.org/PathwayBrowser/#/R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine TAS Homo sapiens 4728 R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 4728 R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 4728 R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 4728 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4728 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4728 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 4728 R-MMU-109534 https://reactome.org/PathwayBrowser/#/R-MMU-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4728 R-MMU-109536 https://reactome.org/PathwayBrowser/#/R-MMU-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Mus musculus 4728 R-MMU-109538 https://reactome.org/PathwayBrowser/#/R-MMU-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Mus musculus 4728 R-MMU-109903 https://reactome.org/PathwayBrowser/#/R-MMU-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Mus musculus 4728 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 4728 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 4728 R-MMU-73598 https://reactome.org/PathwayBrowser/#/R-MMU-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Mus musculus 4728 R-MMU-73599 https://reactome.org/PathwayBrowser/#/R-MMU-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Mus musculus 4728 R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 4728 R-MMU-8954327 https://reactome.org/PathwayBrowser/#/R-MMU-8954327 UCKL1 phosphorylates urindine, cytidine IEA Mus musculus 4728 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4728 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4728 R-PFA-109534 https://reactome.org/PathwayBrowser/#/R-PFA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4728 R-PFA-109536 https://reactome.org/PathwayBrowser/#/R-PFA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Plasmodium falciparum 4728 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 4728 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 4728 R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 4728 R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 4728 R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 4728 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4728 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4728 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 4728 R-RNO-109534 https://reactome.org/PathwayBrowser/#/R-RNO-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4728 R-RNO-109536 https://reactome.org/PathwayBrowser/#/R-RNO-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Rattus norvegicus 4728 R-RNO-109538 https://reactome.org/PathwayBrowser/#/R-RNO-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Rattus norvegicus 4728 R-RNO-109903 https://reactome.org/PathwayBrowser/#/R-RNO-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Rattus norvegicus 4728 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 4728 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 4728 R-RNO-73598 https://reactome.org/PathwayBrowser/#/R-RNO-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Rattus norvegicus 4728 R-RNO-73599 https://reactome.org/PathwayBrowser/#/R-RNO-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Rattus norvegicus 4728 R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 4728 R-RNO-8954327 https://reactome.org/PathwayBrowser/#/R-RNO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Rattus norvegicus 4728 R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 4728 R-SCE-8954327 https://reactome.org/PathwayBrowser/#/R-SCE-8954327 UCKL1 phosphorylates urindine, cytidine IEA Saccharomyces cerevisiae 4728 R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 4728 R-SPO-8954327 https://reactome.org/PathwayBrowser/#/R-SPO-8954327 UCKL1 phosphorylates urindine, cytidine IEA Schizosaccharomyces pombe 4728 R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 4728 R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 4728 R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 4728 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4728 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4728 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 4728 R-SSC-109534 https://reactome.org/PathwayBrowser/#/R-SSC-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4728 R-SSC-109536 https://reactome.org/PathwayBrowser/#/R-SSC-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Sus scrofa 4728 R-SSC-109538 https://reactome.org/PathwayBrowser/#/R-SSC-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Sus scrofa 4728 R-SSC-109903 https://reactome.org/PathwayBrowser/#/R-SSC-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Sus scrofa 4728 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 4728 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 4728 R-SSC-73599 https://reactome.org/PathwayBrowser/#/R-SSC-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Sus scrofa 4728 R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 4728 R-SSC-8954327 https://reactome.org/PathwayBrowser/#/R-SSC-8954327 UCKL1 phosphorylates urindine, cytidine IEA Sus scrofa 4728 R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 4728 R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 4728 R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 4728 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 4728 R-XTR-109534 https://reactome.org/PathwayBrowser/#/R-XTR-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4728 R-XTR-109536 https://reactome.org/PathwayBrowser/#/R-XTR-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 IEA Xenopus tropicalis 4728 R-XTR-109538 https://reactome.org/PathwayBrowser/#/R-XTR-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 IEA Xenopus tropicalis 4728 R-XTR-109903 https://reactome.org/PathwayBrowser/#/R-XTR-109903 cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] IEA Xenopus tropicalis 4728 R-XTR-73598 https://reactome.org/PathwayBrowser/#/R-XTR-73598 (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) IEA Xenopus tropicalis 4728 R-XTR-73599 https://reactome.org/PathwayBrowser/#/R-XTR-73599 cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] IEA Xenopus tropicalis 4728 R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 4728 R-XTR-8954327 https://reactome.org/PathwayBrowser/#/R-XTR-8954327 UCKL1 phosphorylates urindine, cytidine IEA Xenopus tropicalis 4743 R-BTA-9708104 https://reactome.org/PathwayBrowser/#/R-BTA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Bos taurus 4743 R-CFA-9708104 https://reactome.org/PathwayBrowser/#/R-CFA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Canis familiaris 4743 R-DME-9708104 https://reactome.org/PathwayBrowser/#/R-DME-9708104 PDE5A dimer binds PDE5A inhibitors IEA Drosophila melanogaster 4743 R-GGA-9708104 https://reactome.org/PathwayBrowser/#/R-GGA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Gallus gallus 4743 R-HSA-9708104 https://reactome.org/PathwayBrowser/#/R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors TAS Homo sapiens 4743 R-MMU-9708104 https://reactome.org/PathwayBrowser/#/R-MMU-9708104 PDE5A dimer binds PDE5A inhibitors IEA Mus musculus 4743 R-RNO-9708104 https://reactome.org/PathwayBrowser/#/R-RNO-9708104 PDE5A dimer binds PDE5A inhibitors IEA Rattus norvegicus 4743 R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa 4743 R-XTR-9708104 https://reactome.org/PathwayBrowser/#/R-XTR-9708104 PDE5A dimer binds PDE5A inhibitors IEA Xenopus tropicalis 4744 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 4744 R-HSA-9686790 https://reactome.org/PathwayBrowser/#/R-HSA-9686790 ER-alpha glucosidases bind ER-alpha glucosidase inhibitors TAS Homo sapiens 4744 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 4747 R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 4747 R-BTA-194121 https://reactome.org/PathwayBrowser/#/R-BTA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Bos taurus 4747 R-BTA-194130 https://reactome.org/PathwayBrowser/#/R-BTA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Bos taurus 4747 R-BTA-194153 https://reactome.org/PathwayBrowser/#/R-BTA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Bos taurus 4747 R-BTA-194187 https://reactome.org/PathwayBrowser/#/R-BTA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Bos taurus 4747 R-BTA-9733964 https://reactome.org/PathwayBrowser/#/R-BTA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Bos taurus 4747 R-BTA-9733969 https://reactome.org/PathwayBrowser/#/R-BTA-9733969 Bile salts dissociate from FABP6 IEA Bos taurus 4747 R-BTA-9733973 https://reactome.org/PathwayBrowser/#/R-BTA-9733973 Bile salts bind FABP6 IEA Bos taurus 4747 R-CEL-159431 https://reactome.org/PathwayBrowser/#/R-CEL-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Caenorhabditis elegans 4747 R-CEL-193491 https://reactome.org/PathwayBrowser/#/R-CEL-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Caenorhabditis elegans 4747 R-CEL-194121 https://reactome.org/PathwayBrowser/#/R-CEL-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 4747 R-CEL-194130 https://reactome.org/PathwayBrowser/#/R-CEL-194130 Transport (influx) of bile salts and acids by OATP-A IEA Caenorhabditis elegans 4747 R-CEL-194153 https://reactome.org/PathwayBrowser/#/R-CEL-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Caenorhabditis elegans 4747 R-CEL-194187 https://reactome.org/PathwayBrowser/#/R-CEL-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 4747 R-CEL-9733969 https://reactome.org/PathwayBrowser/#/R-CEL-9733969 Bile salts dissociate from FABP6 IEA Caenorhabditis elegans 4747 R-CEL-9733973 https://reactome.org/PathwayBrowser/#/R-CEL-9733973 Bile salts bind FABP6 IEA Caenorhabditis elegans 4747 R-CFA-159431 https://reactome.org/PathwayBrowser/#/R-CFA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Canis familiaris 4747 R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 4747 R-CFA-193491 https://reactome.org/PathwayBrowser/#/R-CFA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Canis familiaris 4747 R-CFA-194121 https://reactome.org/PathwayBrowser/#/R-CFA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Canis familiaris 4747 R-CFA-194130 https://reactome.org/PathwayBrowser/#/R-CFA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Canis familiaris 4747 R-CFA-194153 https://reactome.org/PathwayBrowser/#/R-CFA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Canis familiaris 4747 R-CFA-194187 https://reactome.org/PathwayBrowser/#/R-CFA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Canis familiaris 4747 R-CFA-9733964 https://reactome.org/PathwayBrowser/#/R-CFA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Canis familiaris 4747 R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 4747 R-DDI-194153 https://reactome.org/PathwayBrowser/#/R-DDI-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 4747 R-DME-194121 https://reactome.org/PathwayBrowser/#/R-DME-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 4747 R-DME-194130 https://reactome.org/PathwayBrowser/#/R-DME-194130 Transport (influx) of bile salts and acids by OATP-A IEA Drosophila melanogaster 4747 R-DME-194153 https://reactome.org/PathwayBrowser/#/R-DME-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Drosophila melanogaster 4747 R-DME-194187 https://reactome.org/PathwayBrowser/#/R-DME-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 4747 R-DME-9733969 https://reactome.org/PathwayBrowser/#/R-DME-9733969 Bile salts dissociate from FABP6 IEA Drosophila melanogaster 4747 R-DME-9733973 https://reactome.org/PathwayBrowser/#/R-DME-9733973 Bile salts bind FABP6 IEA Drosophila melanogaster 4747 R-DRE-194121 https://reactome.org/PathwayBrowser/#/R-DRE-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Danio rerio 4747 R-DRE-194130 https://reactome.org/PathwayBrowser/#/R-DRE-194130 Transport (influx) of bile salts and acids by OATP-A IEA Danio rerio 4747 R-DRE-194187 https://reactome.org/PathwayBrowser/#/R-DRE-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Danio rerio 4747 R-DRE-9733969 https://reactome.org/PathwayBrowser/#/R-DRE-9733969 Bile salts dissociate from FABP6 IEA Danio rerio 4747 R-DRE-9733973 https://reactome.org/PathwayBrowser/#/R-DRE-9733973 Bile salts bind FABP6 IEA Danio rerio 4747 R-GGA-159431 https://reactome.org/PathwayBrowser/#/R-GGA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Gallus gallus 4747 R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 4747 R-GGA-193491 https://reactome.org/PathwayBrowser/#/R-GGA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Gallus gallus 4747 R-GGA-194130 https://reactome.org/PathwayBrowser/#/R-GGA-194130 Transport (influx) of bile salts and acids by OATP-A IEA Gallus gallus 4747 R-GGA-194153 https://reactome.org/PathwayBrowser/#/R-GGA-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Gallus gallus 4747 R-GGA-194187 https://reactome.org/PathwayBrowser/#/R-GGA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Gallus gallus 4747 R-GGA-9733964 https://reactome.org/PathwayBrowser/#/R-GGA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Gallus gallus 4747 R-GGA-9733969 https://reactome.org/PathwayBrowser/#/R-GGA-9733969 Bile salts dissociate from FABP6 IEA Gallus gallus 4747 R-GGA-9733973 https://reactome.org/PathwayBrowser/#/R-GGA-9733973 Bile salts bind FABP6 IEA Gallus gallus 4747 R-HSA-159431 https://reactome.org/PathwayBrowser/#/R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine TAS Homo sapiens 4747 R-HSA-192315 https://reactome.org/PathwayBrowser/#/R-HSA-192315 Bile salts are translocated from the peroxisomal matrix to the cytosol TAS Homo sapiens 4747 R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 4747 R-HSA-193491 https://reactome.org/PathwayBrowser/#/R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate TAS Homo sapiens 4747 R-HSA-194121 https://reactome.org/PathwayBrowser/#/R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol TAS Homo sapiens 4747 R-HSA-194130 https://reactome.org/PathwayBrowser/#/R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A TAS Homo sapiens 4747 R-HSA-194153 https://reactome.org/PathwayBrowser/#/R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region TAS Homo sapiens 4747 R-HSA-194187 https://reactome.org/PathwayBrowser/#/R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol TAS Homo sapiens 4747 R-HSA-5678517 https://reactome.org/PathwayBrowser/#/R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region TAS Homo sapiens 4747 R-HSA-9733964 https://reactome.org/PathwayBrowser/#/R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region TAS Homo sapiens 4747 R-HSA-9733969 https://reactome.org/PathwayBrowser/#/R-HSA-9733969 Bile salts dissociate from FABP6 TAS Homo sapiens 4747 R-HSA-9733973 https://reactome.org/PathwayBrowser/#/R-HSA-9733973 Bile salts bind FABP6 TAS Homo sapiens 4747 R-MMU-159431 https://reactome.org/PathwayBrowser/#/R-MMU-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Mus musculus 4747 R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 4747 R-MMU-193491 https://reactome.org/PathwayBrowser/#/R-MMU-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Mus musculus 4747 R-MMU-194121 https://reactome.org/PathwayBrowser/#/R-MMU-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Mus musculus 4747 R-MMU-194130 https://reactome.org/PathwayBrowser/#/R-MMU-194130 Transport (influx) of bile salts and acids by OATP-A IEA Mus musculus 4747 R-MMU-194153 https://reactome.org/PathwayBrowser/#/R-MMU-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Mus musculus 4747 R-MMU-194187 https://reactome.org/PathwayBrowser/#/R-MMU-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Mus musculus 4747 R-MMU-9733964 https://reactome.org/PathwayBrowser/#/R-MMU-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Mus musculus 4747 R-MMU-9733969 https://reactome.org/PathwayBrowser/#/R-MMU-9733969 Bile salts dissociate from FABP6 IEA Mus musculus 4747 R-MMU-9733973 https://reactome.org/PathwayBrowser/#/R-MMU-9733973 Bile salts bind FABP6 IEA Mus musculus 4747 R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 4747 R-RNO-159431 https://reactome.org/PathwayBrowser/#/R-RNO-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Rattus norvegicus 4747 R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 4747 R-RNO-193491 https://reactome.org/PathwayBrowser/#/R-RNO-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Rattus norvegicus 4747 R-RNO-194121 https://reactome.org/PathwayBrowser/#/R-RNO-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Rattus norvegicus 4747 R-RNO-194130 https://reactome.org/PathwayBrowser/#/R-RNO-194130 Transport (influx) of bile salts and acids by OATP-A IEA Rattus norvegicus 4747 R-RNO-194153 https://reactome.org/PathwayBrowser/#/R-RNO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 4747 R-RNO-194187 https://reactome.org/PathwayBrowser/#/R-RNO-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Rattus norvegicus 4747 R-RNO-9733964 https://reactome.org/PathwayBrowser/#/R-RNO-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 4747 R-RNO-9733969 https://reactome.org/PathwayBrowser/#/R-RNO-9733969 Bile salts dissociate from FABP6 IEA Rattus norvegicus 4747 R-RNO-9733973 https://reactome.org/PathwayBrowser/#/R-RNO-9733973 Bile salts bind FABP6 IEA Rattus norvegicus 4747 R-SCE-194153 https://reactome.org/PathwayBrowser/#/R-SCE-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Saccharomyces cerevisiae 4747 R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 4747 R-SPO-194153 https://reactome.org/PathwayBrowser/#/R-SPO-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 4747 R-SSC-159431 https://reactome.org/PathwayBrowser/#/R-SSC-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Sus scrofa 4747 R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 4747 R-SSC-193491 https://reactome.org/PathwayBrowser/#/R-SSC-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Sus scrofa 4747 R-SSC-194121 https://reactome.org/PathwayBrowser/#/R-SSC-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Sus scrofa 4747 R-SSC-194130 https://reactome.org/PathwayBrowser/#/R-SSC-194130 Transport (influx) of bile salts and acids by OATP-A IEA Sus scrofa 4747 R-SSC-194153 https://reactome.org/PathwayBrowser/#/R-SSC-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Sus scrofa 4747 R-SSC-194187 https://reactome.org/PathwayBrowser/#/R-SSC-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Sus scrofa 4747 R-SSC-9733964 https://reactome.org/PathwayBrowser/#/R-SSC-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Sus scrofa 4747 R-SSC-9733969 https://reactome.org/PathwayBrowser/#/R-SSC-9733969 Bile salts dissociate from FABP6 IEA Sus scrofa 4747 R-SSC-9733973 https://reactome.org/PathwayBrowser/#/R-SSC-9733973 Bile salts bind FABP6 IEA Sus scrofa 4747 R-XTR-159431 https://reactome.org/PathwayBrowser/#/R-XTR-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine IEA Xenopus tropicalis 4747 R-XTR-193491 https://reactome.org/PathwayBrowser/#/R-XTR-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate IEA Xenopus tropicalis 4747 R-XTR-194121 https://reactome.org/PathwayBrowser/#/R-XTR-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 4747 R-XTR-194153 https://reactome.org/PathwayBrowser/#/R-XTR-194153 ABCC3 transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 4747 R-XTR-194187 https://reactome.org/PathwayBrowser/#/R-XTR-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 4747 R-XTR-9733964 https://reactome.org/PathwayBrowser/#/R-XTR-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region IEA Xenopus tropicalis 4747 R-XTR-9733969 https://reactome.org/PathwayBrowser/#/R-XTR-9733969 Bile salts dissociate from FABP6 IEA Xenopus tropicalis 4747 R-XTR-9733973 https://reactome.org/PathwayBrowser/#/R-XTR-9733973 Bile salts bind FABP6 IEA Xenopus tropicalis 4749 R-BTA-176664 https://reactome.org/PathwayBrowser/#/R-BTA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Bos taurus 4749 R-BTA-561059 https://reactome.org/PathwayBrowser/#/R-BTA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Bos taurus 4749 R-BTA-879562 https://reactome.org/PathwayBrowser/#/R-BTA-879562 SLCO2B1 has a narrow substrate specificity IEA Bos taurus 4749 R-CEL-561059 https://reactome.org/PathwayBrowser/#/R-CEL-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Caenorhabditis elegans 4749 R-CEL-879562 https://reactome.org/PathwayBrowser/#/R-CEL-879562 SLCO2B1 has a narrow substrate specificity IEA Caenorhabditis elegans 4749 R-CFA-176664 https://reactome.org/PathwayBrowser/#/R-CFA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Canis familiaris 4749 R-CFA-561059 https://reactome.org/PathwayBrowser/#/R-CFA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Canis familiaris 4749 R-CFA-879562 https://reactome.org/PathwayBrowser/#/R-CFA-879562 SLCO2B1 has a narrow substrate specificity IEA Canis familiaris 4749 R-DME-176664 https://reactome.org/PathwayBrowser/#/R-DME-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Drosophila melanogaster 4749 R-DME-561059 https://reactome.org/PathwayBrowser/#/R-DME-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Drosophila melanogaster 4749 R-DME-879562 https://reactome.org/PathwayBrowser/#/R-DME-879562 SLCO2B1 has a narrow substrate specificity IEA Drosophila melanogaster 4749 R-DRE-176664 https://reactome.org/PathwayBrowser/#/R-DRE-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Danio rerio 4749 R-DRE-561059 https://reactome.org/PathwayBrowser/#/R-DRE-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Danio rerio 4749 R-DRE-879562 https://reactome.org/PathwayBrowser/#/R-DRE-879562 SLCO2B1 has a narrow substrate specificity IEA Danio rerio 4749 R-GGA-176664 https://reactome.org/PathwayBrowser/#/R-GGA-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Gallus gallus 4749 R-GGA-561059 https://reactome.org/PathwayBrowser/#/R-GGA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Gallus gallus 4749 R-GGA-879562 https://reactome.org/PathwayBrowser/#/R-GGA-879562 SLCO2B1 has a narrow substrate specificity IEA Gallus gallus 4749 R-HSA-176664 https://reactome.org/PathwayBrowser/#/R-HSA-176664 estrone + PAPS => estrone 3-sulfate + PAP TAS Homo sapiens 4749 R-HSA-561059 https://reactome.org/PathwayBrowser/#/R-HSA-561059 OAT2 and OAT4 mediate transport of sulphate conjugates TAS Homo sapiens 4749 R-HSA-879562 https://reactome.org/PathwayBrowser/#/R-HSA-879562 SLCO2B1 has a narrow substrate specificity TAS Homo sapiens 4749 R-MMU-176664 https://reactome.org/PathwayBrowser/#/R-MMU-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Mus musculus 4749 R-MMU-561059 https://reactome.org/PathwayBrowser/#/R-MMU-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Mus musculus 4749 R-MMU-879562 https://reactome.org/PathwayBrowser/#/R-MMU-879562 SLCO2B1 has a narrow substrate specificity IEA Mus musculus 4749 R-RNO-176664 https://reactome.org/PathwayBrowser/#/R-RNO-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Rattus norvegicus 4749 R-RNO-561059 https://reactome.org/PathwayBrowser/#/R-RNO-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Rattus norvegicus 4749 R-RNO-879562 https://reactome.org/PathwayBrowser/#/R-RNO-879562 SLCO2B1 has a narrow substrate specificity IEA Rattus norvegicus 4749 R-SSC-176664 https://reactome.org/PathwayBrowser/#/R-SSC-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Sus scrofa 4749 R-SSC-561059 https://reactome.org/PathwayBrowser/#/R-SSC-561059 OAT2 and OAT4 mediate transport of sulphate conjugates IEA Sus scrofa 4749 R-SSC-879562 https://reactome.org/PathwayBrowser/#/R-SSC-879562 SLCO2B1 has a narrow substrate specificity IEA Sus scrofa 4749 R-XTR-176664 https://reactome.org/PathwayBrowser/#/R-XTR-176664 estrone + PAPS => estrone 3-sulfate + PAP IEA Xenopus tropicalis 4749 R-XTR-879562 https://reactome.org/PathwayBrowser/#/R-XTR-879562 SLCO2B1 has a narrow substrate specificity IEA Xenopus tropicalis 4754 R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 4754 R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 4754 R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 4754 R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 4754 R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 4754 R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 4754 R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 4754 R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 4780 R-BTA-165026 https://reactome.org/PathwayBrowser/#/R-BTA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Bos taurus 4780 R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A transfers PALM to CAR IEA Bos taurus 4780 R-BTA-200410 https://reactome.org/PathwayBrowser/#/R-BTA-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Bos taurus 4780 R-BTA-200424 https://reactome.org/PathwayBrowser/#/R-BTA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Bos taurus 4780 R-BTA-390281 https://reactome.org/PathwayBrowser/#/R-BTA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Bos taurus 4780 R-BTA-390284 https://reactome.org/PathwayBrowser/#/R-BTA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Bos taurus 4780 R-BTA-390291 https://reactome.org/PathwayBrowser/#/R-BTA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Bos taurus 4780 R-BTA-549297 https://reactome.org/PathwayBrowser/#/R-BTA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Bos taurus 4780 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 4780 R-BTA-9911362 https://reactome.org/PathwayBrowser/#/R-BTA-9911362 CPT1B transfers PALM to CAR IEA Bos taurus 4780 R-CEL-165026 https://reactome.org/PathwayBrowser/#/R-CEL-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Caenorhabditis elegans 4780 R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A transfers PALM to CAR IEA Caenorhabditis elegans 4780 R-CEL-200410 https://reactome.org/PathwayBrowser/#/R-CEL-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Caenorhabditis elegans 4780 R-CEL-200424 https://reactome.org/PathwayBrowser/#/R-CEL-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Caenorhabditis elegans 4780 R-CEL-390281 https://reactome.org/PathwayBrowser/#/R-CEL-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Caenorhabditis elegans 4780 R-CEL-390284 https://reactome.org/PathwayBrowser/#/R-CEL-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Caenorhabditis elegans 4780 R-CEL-390291 https://reactome.org/PathwayBrowser/#/R-CEL-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Caenorhabditis elegans 4780 R-CEL-549297 https://reactome.org/PathwayBrowser/#/R-CEL-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 4780 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 4780 R-CEL-9911362 https://reactome.org/PathwayBrowser/#/R-CEL-9911362 CPT1B transfers PALM to CAR IEA Caenorhabditis elegans 4780 R-CFA-165026 https://reactome.org/PathwayBrowser/#/R-CFA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Canis familiaris 4780 R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A transfers PALM to CAR IEA Canis familiaris 4780 R-CFA-200410 https://reactome.org/PathwayBrowser/#/R-CFA-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Canis familiaris 4780 R-CFA-200424 https://reactome.org/PathwayBrowser/#/R-CFA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Canis familiaris 4780 R-CFA-390281 https://reactome.org/PathwayBrowser/#/R-CFA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Canis familiaris 4780 R-CFA-390284 https://reactome.org/PathwayBrowser/#/R-CFA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Canis familiaris 4780 R-CFA-390291 https://reactome.org/PathwayBrowser/#/R-CFA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Canis familiaris 4780 R-CFA-549297 https://reactome.org/PathwayBrowser/#/R-CFA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Canis familiaris 4780 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 4780 R-CFA-9911362 https://reactome.org/PathwayBrowser/#/R-CFA-9911362 CPT1B transfers PALM to CAR IEA Canis familiaris 4780 R-DME-165026 https://reactome.org/PathwayBrowser/#/R-DME-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Drosophila melanogaster 4780 R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A transfers PALM to CAR IEA Drosophila melanogaster 4780 R-DME-200410 https://reactome.org/PathwayBrowser/#/R-DME-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Drosophila melanogaster 4780 R-DME-200424 https://reactome.org/PathwayBrowser/#/R-DME-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Drosophila melanogaster 4780 R-DME-390281 https://reactome.org/PathwayBrowser/#/R-DME-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Drosophila melanogaster 4780 R-DME-390284 https://reactome.org/PathwayBrowser/#/R-DME-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Drosophila melanogaster 4780 R-DME-390291 https://reactome.org/PathwayBrowser/#/R-DME-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Drosophila melanogaster 4780 R-DME-549297 https://reactome.org/PathwayBrowser/#/R-DME-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 4780 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 4780 R-DME-9911362 https://reactome.org/PathwayBrowser/#/R-DME-9911362 CPT1B transfers PALM to CAR IEA Drosophila melanogaster 4780 R-DRE-165026 https://reactome.org/PathwayBrowser/#/R-DRE-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Danio rerio 4780 R-DRE-200410 https://reactome.org/PathwayBrowser/#/R-DRE-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Danio rerio 4780 R-DRE-200424 https://reactome.org/PathwayBrowser/#/R-DRE-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Danio rerio 4780 R-DRE-390281 https://reactome.org/PathwayBrowser/#/R-DRE-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Danio rerio 4780 R-DRE-390284 https://reactome.org/PathwayBrowser/#/R-DRE-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Danio rerio 4780 R-DRE-390291 https://reactome.org/PathwayBrowser/#/R-DRE-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Danio rerio 4780 R-DRE-549297 https://reactome.org/PathwayBrowser/#/R-DRE-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Danio rerio 4780 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 4780 R-DRE-9911362 https://reactome.org/PathwayBrowser/#/R-DRE-9911362 CPT1B transfers PALM to CAR IEA Danio rerio 4780 R-GGA-165026 https://reactome.org/PathwayBrowser/#/R-GGA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Gallus gallus 4780 R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A transfers PALM to CAR IEA Gallus gallus 4780 R-GGA-200410 https://reactome.org/PathwayBrowser/#/R-GGA-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Gallus gallus 4780 R-GGA-200424 https://reactome.org/PathwayBrowser/#/R-GGA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Gallus gallus 4780 R-GGA-390281 https://reactome.org/PathwayBrowser/#/R-GGA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Gallus gallus 4780 R-GGA-390284 https://reactome.org/PathwayBrowser/#/R-GGA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Gallus gallus 4780 R-GGA-390291 https://reactome.org/PathwayBrowser/#/R-GGA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Gallus gallus 4780 R-GGA-549297 https://reactome.org/PathwayBrowser/#/R-GGA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Gallus gallus 4780 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 4780 R-HSA-164967 https://reactome.org/PathwayBrowser/#/R-HSA-164967 Unknown carnitine exporter transports CAR from the cytosol to the extracellular space TAS Homo sapiens 4780 R-HSA-165026 https://reactome.org/PathwayBrowser/#/R-HSA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol TAS Homo sapiens 4780 R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A transfers PALM to CAR TAS Homo sapiens 4780 R-HSA-200410 https://reactome.org/PathwayBrowser/#/R-HSA-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA TAS Homo sapiens 4780 R-HSA-200424 https://reactome.org/PathwayBrowser/#/R-HSA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane TAS Homo sapiens 4780 R-HSA-390281 https://reactome.org/PathwayBrowser/#/R-HSA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH TAS Homo sapiens 4780 R-HSA-390284 https://reactome.org/PathwayBrowser/#/R-HSA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH TAS Homo sapiens 4780 R-HSA-390291 https://reactome.org/PathwayBrowser/#/R-HSA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH TAS Homo sapiens 4780 R-HSA-549297 https://reactome.org/PathwayBrowser/#/R-HSA-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol TAS Homo sapiens 4780 R-HSA-5625674 https://reactome.org/PathwayBrowser/#/R-HSA-5625674 Defective SLC22A5 does not cotransport CAR, Na+ from extracellular region to cytosol TAS Homo sapiens 4780 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 4780 R-HSA-8949399 https://reactome.org/PathwayBrowser/#/R-HSA-8949399 CAR translocates from the cytosol to the mitochondrial intermembrane space TAS Homo sapiens 4780 R-HSA-9911362 https://reactome.org/PathwayBrowser/#/R-HSA-9911362 CPT1B transfers PALM to CAR TAS Homo sapiens 4780 R-MMU-165026 https://reactome.org/PathwayBrowser/#/R-MMU-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Mus musculus 4780 R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A transfers PALM to CAR IEA Mus musculus 4780 R-MMU-200410 https://reactome.org/PathwayBrowser/#/R-MMU-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Mus musculus 4780 R-MMU-200424 https://reactome.org/PathwayBrowser/#/R-MMU-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Mus musculus 4780 R-MMU-390281 https://reactome.org/PathwayBrowser/#/R-MMU-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Mus musculus 4780 R-MMU-390284 https://reactome.org/PathwayBrowser/#/R-MMU-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Mus musculus 4780 R-MMU-390291 https://reactome.org/PathwayBrowser/#/R-MMU-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Mus musculus 4780 R-MMU-549297 https://reactome.org/PathwayBrowser/#/R-MMU-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Mus musculus 4780 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 4780 R-MMU-9911362 https://reactome.org/PathwayBrowser/#/R-MMU-9911362 CPT1B transfers PALM to CAR IEA Mus musculus 4780 R-RNO-165026 https://reactome.org/PathwayBrowser/#/R-RNO-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Rattus norvegicus 4780 R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A transfers PALM to CAR IEA Rattus norvegicus 4780 R-RNO-200410 https://reactome.org/PathwayBrowser/#/R-RNO-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Rattus norvegicus 4780 R-RNO-200424 https://reactome.org/PathwayBrowser/#/R-RNO-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Rattus norvegicus 4780 R-RNO-390281 https://reactome.org/PathwayBrowser/#/R-RNO-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Rattus norvegicus 4780 R-RNO-390284 https://reactome.org/PathwayBrowser/#/R-RNO-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Rattus norvegicus 4780 R-RNO-390291 https://reactome.org/PathwayBrowser/#/R-RNO-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Rattus norvegicus 4780 R-RNO-549297 https://reactome.org/PathwayBrowser/#/R-RNO-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Rattus norvegicus 4780 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 4780 R-RNO-9911362 https://reactome.org/PathwayBrowser/#/R-RNO-9911362 CPT1B transfers PALM to CAR IEA Rattus norvegicus 4780 R-SCE-200424 https://reactome.org/PathwayBrowser/#/R-SCE-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Saccharomyces cerevisiae 4780 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 4780 R-SPO-200424 https://reactome.org/PathwayBrowser/#/R-SPO-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Schizosaccharomyces pombe 4780 R-SSC-165026 https://reactome.org/PathwayBrowser/#/R-SSC-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Sus scrofa 4780 R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A transfers PALM to CAR IEA Sus scrofa 4780 R-SSC-200410 https://reactome.org/PathwayBrowser/#/R-SSC-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Sus scrofa 4780 R-SSC-200424 https://reactome.org/PathwayBrowser/#/R-SSC-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Sus scrofa 4780 R-SSC-390281 https://reactome.org/PathwayBrowser/#/R-SSC-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Sus scrofa 4780 R-SSC-390284 https://reactome.org/PathwayBrowser/#/R-SSC-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Sus scrofa 4780 R-SSC-390291 https://reactome.org/PathwayBrowser/#/R-SSC-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Sus scrofa 4780 R-SSC-549297 https://reactome.org/PathwayBrowser/#/R-SSC-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Sus scrofa 4780 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 4780 R-SSC-9911362 https://reactome.org/PathwayBrowser/#/R-SSC-9911362 CPT1B transfers PALM to CAR IEA Sus scrofa 4780 R-XTR-165026 https://reactome.org/PathwayBrowser/#/R-XTR-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol IEA Xenopus tropicalis 4780 R-XTR-200410 https://reactome.org/PathwayBrowser/#/R-XTR-200410 CPT2 converts palmitoyl carnitine to palmitoyl-CoA IEA Xenopus tropicalis 4780 R-XTR-200424 https://reactome.org/PathwayBrowser/#/R-XTR-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane IEA Xenopus tropicalis 4780 R-XTR-390281 https://reactome.org/PathwayBrowser/#/R-XTR-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH IEA Xenopus tropicalis 4780 R-XTR-390284 https://reactome.org/PathwayBrowser/#/R-XTR-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH IEA Xenopus tropicalis 4780 R-XTR-390291 https://reactome.org/PathwayBrowser/#/R-XTR-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH IEA Xenopus tropicalis 4780 R-XTR-549297 https://reactome.org/PathwayBrowser/#/R-XTR-549297 SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 4780 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 4780 R-XTR-9911362 https://reactome.org/PathwayBrowser/#/R-XTR-9911362 CPT1B transfers PALM to CAR IEA Xenopus tropicalis 4781 R-BTA-1650808 https://reactome.org/PathwayBrowser/#/R-BTA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Bos taurus 4781 R-BTA-1980233 https://reactome.org/PathwayBrowser/#/R-BTA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Bos taurus 4781 R-CEL-1650808 https://reactome.org/PathwayBrowser/#/R-CEL-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Caenorhabditis elegans 4781 R-CFA-1650808 https://reactome.org/PathwayBrowser/#/R-CFA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Canis familiaris 4781 R-CFA-1980233 https://reactome.org/PathwayBrowser/#/R-CFA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Canis familiaris 4781 R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio 4781 R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus 4781 R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus 4781 R-HSA-1650808 https://reactome.org/PathwayBrowser/#/R-HSA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines TAS Homo sapiens 4781 R-HSA-1980233 https://reactome.org/PathwayBrowser/#/R-HSA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen TAS Homo sapiens 4781 R-HSA-8948226 https://reactome.org/PathwayBrowser/#/R-HSA-8948226 Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates TAS Homo sapiens 4781 R-HSA-8948230 https://reactome.org/PathwayBrowser/#/R-HSA-8948230 P3HB binds 4-Hyp-collagen propeptides TAS Homo sapiens 4781 R-MMU-1650808 https://reactome.org/PathwayBrowser/#/R-MMU-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Mus musculus 4781 R-MMU-1980233 https://reactome.org/PathwayBrowser/#/R-MMU-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Mus musculus 4781 R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus 4781 R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus 4781 R-SSC-1650808 https://reactome.org/PathwayBrowser/#/R-SSC-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Sus scrofa 4781 R-XTR-1650808 https://reactome.org/PathwayBrowser/#/R-XTR-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Xenopus tropicalis 4781 R-XTR-1980233 https://reactome.org/PathwayBrowser/#/R-XTR-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Xenopus tropicalis 4787 R-BTA-199219 https://reactome.org/PathwayBrowser/#/R-BTA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Bos taurus 4787 R-BTA-2993447 https://reactome.org/PathwayBrowser/#/R-BTA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Bos taurus 4787 R-BTA-2993799 https://reactome.org/PathwayBrowser/#/R-BTA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Bos taurus 4787 R-BTA-2993802 https://reactome.org/PathwayBrowser/#/R-BTA-2993802 HLCS biotinylates PC:Mn2+ IEA Bos taurus 4787 R-BTA-2993814 https://reactome.org/PathwayBrowser/#/R-BTA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Bos taurus 4787 R-BTA-3076905 https://reactome.org/PathwayBrowser/#/R-BTA-3076905 Extracellular BTD hydrolyses BCTN IEA Bos taurus 4787 R-BTA-4167509 https://reactome.org/PathwayBrowser/#/R-BTA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Bos taurus 4787 R-BTA-4167511 https://reactome.org/PathwayBrowser/#/R-BTA-4167511 HLCS biotinylates ACACB IEA Bos taurus 4787 R-BTA-429581 https://reactome.org/PathwayBrowser/#/R-BTA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Bos taurus 4787 R-CEL-2993447 https://reactome.org/PathwayBrowser/#/R-CEL-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Caenorhabditis elegans 4787 R-CEL-2993799 https://reactome.org/PathwayBrowser/#/R-CEL-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Caenorhabditis elegans 4787 R-CEL-2993802 https://reactome.org/PathwayBrowser/#/R-CEL-2993802 HLCS biotinylates PC:Mn2+ IEA Caenorhabditis elegans 4787 R-CEL-2993814 https://reactome.org/PathwayBrowser/#/R-CEL-2993814 HLCS biotinylates ACACA:Mn2+ IEA Caenorhabditis elegans 4787 R-CEL-4167511 https://reactome.org/PathwayBrowser/#/R-CEL-4167511 HLCS biotinylates ACACB IEA Caenorhabditis elegans 4787 R-CFA-199219 https://reactome.org/PathwayBrowser/#/R-CFA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Canis familiaris 4787 R-CFA-2993447 https://reactome.org/PathwayBrowser/#/R-CFA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Canis familiaris 4787 R-CFA-2993799 https://reactome.org/PathwayBrowser/#/R-CFA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Canis familiaris 4787 R-CFA-2993802 https://reactome.org/PathwayBrowser/#/R-CFA-2993802 HLCS biotinylates PC:Mn2+ IEA Canis familiaris 4787 R-CFA-2993814 https://reactome.org/PathwayBrowser/#/R-CFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Canis familiaris 4787 R-CFA-3076905 https://reactome.org/PathwayBrowser/#/R-CFA-3076905 Extracellular BTD hydrolyses BCTN IEA Canis familiaris 4787 R-CFA-4167509 https://reactome.org/PathwayBrowser/#/R-CFA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Canis familiaris 4787 R-CFA-4167511 https://reactome.org/PathwayBrowser/#/R-CFA-4167511 HLCS biotinylates ACACB IEA Canis familiaris 4787 R-CFA-429581 https://reactome.org/PathwayBrowser/#/R-CFA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Canis familiaris 4787 R-DDI-2993447 https://reactome.org/PathwayBrowser/#/R-DDI-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Dictyostelium discoideum 4787 R-DDI-2993799 https://reactome.org/PathwayBrowser/#/R-DDI-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Dictyostelium discoideum 4787 R-DDI-2993814 https://reactome.org/PathwayBrowser/#/R-DDI-2993814 HLCS biotinylates ACACA:Mn2+ IEA Dictyostelium discoideum 4787 R-DDI-3076905 https://reactome.org/PathwayBrowser/#/R-DDI-3076905 Extracellular BTD hydrolyses BCTN IEA Dictyostelium discoideum 4787 R-DDI-4167509 https://reactome.org/PathwayBrowser/#/R-DDI-4167509 Mitochondrial BTD hydrolyses BCTN IEA Dictyostelium discoideum 4787 R-DDI-4167511 https://reactome.org/PathwayBrowser/#/R-DDI-4167511 HLCS biotinylates ACACB IEA Dictyostelium discoideum 4787 R-DME-2993799 https://reactome.org/PathwayBrowser/#/R-DME-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Drosophila melanogaster 4787 R-DME-2993802 https://reactome.org/PathwayBrowser/#/R-DME-2993802 HLCS biotinylates PC:Mn2+ IEA Drosophila melanogaster 4787 R-DME-2993814 https://reactome.org/PathwayBrowser/#/R-DME-2993814 HLCS biotinylates ACACA:Mn2+ IEA Drosophila melanogaster 4787 R-DME-3076905 https://reactome.org/PathwayBrowser/#/R-DME-3076905 Extracellular BTD hydrolyses BCTN IEA Drosophila melanogaster 4787 R-DME-4167509 https://reactome.org/PathwayBrowser/#/R-DME-4167509 Mitochondrial BTD hydrolyses BCTN IEA Drosophila melanogaster 4787 R-DME-4167511 https://reactome.org/PathwayBrowser/#/R-DME-4167511 HLCS biotinylates ACACB IEA Drosophila melanogaster 4787 R-DRE-199219 https://reactome.org/PathwayBrowser/#/R-DRE-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Danio rerio 4787 R-DRE-3076905 https://reactome.org/PathwayBrowser/#/R-DRE-3076905 Extracellular BTD hydrolyses BCTN IEA Danio rerio 4787 R-DRE-4167509 https://reactome.org/PathwayBrowser/#/R-DRE-4167509 Mitochondrial BTD hydrolyses BCTN IEA Danio rerio 4787 R-DRE-429581 https://reactome.org/PathwayBrowser/#/R-DRE-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Danio rerio 4787 R-GGA-199219 https://reactome.org/PathwayBrowser/#/R-GGA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Gallus gallus 4787 R-GGA-2993447 https://reactome.org/PathwayBrowser/#/R-GGA-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Gallus gallus 4787 R-GGA-2993799 https://reactome.org/PathwayBrowser/#/R-GGA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Gallus gallus 4787 R-GGA-2993814 https://reactome.org/PathwayBrowser/#/R-GGA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Gallus gallus 4787 R-GGA-3076905 https://reactome.org/PathwayBrowser/#/R-GGA-3076905 Extracellular BTD hydrolyses BCTN IEA Gallus gallus 4787 R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 4787 R-GGA-4167509 https://reactome.org/PathwayBrowser/#/R-GGA-4167509 Mitochondrial BTD hydrolyses BCTN IEA Gallus gallus 4787 R-GGA-429581 https://reactome.org/PathwayBrowser/#/R-GGA-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Gallus gallus 4787 R-HSA-199219 https://reactome.org/PathwayBrowser/#/R-HSA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol TAS Homo sapiens 4787 R-HSA-2993447 https://reactome.org/PathwayBrowser/#/R-HSA-2993447 HLCS biotinylates 6x(PCCA:PCCB) TAS Homo sapiens 4787 R-HSA-2993799 https://reactome.org/PathwayBrowser/#/R-HSA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 TAS Homo sapiens 4787 R-HSA-2993802 https://reactome.org/PathwayBrowser/#/R-HSA-2993802 HLCS biotinylates PC:Mn2+ TAS Homo sapiens 4787 R-HSA-2993814 https://reactome.org/PathwayBrowser/#/R-HSA-2993814 HLCS biotinylates ACACA:Mn2+ TAS Homo sapiens 4787 R-HSA-3076905 https://reactome.org/PathwayBrowser/#/R-HSA-3076905 Extracellular BTD hydrolyses BCTN TAS Homo sapiens 4787 R-HSA-3323184 https://reactome.org/PathwayBrowser/#/R-HSA-3323184 Defective HLCS does not biotinylate ACACA:Mn2+ TAS Homo sapiens 4787 R-HSA-4167509 https://reactome.org/PathwayBrowser/#/R-HSA-4167509 Mitochondrial BTD hydrolyses BCTN TAS Homo sapiens 4787 R-HSA-4167511 https://reactome.org/PathwayBrowser/#/R-HSA-4167511 HLCS biotinylates ACACB TAS Homo sapiens 4787 R-HSA-429581 https://reactome.org/PathwayBrowser/#/R-HSA-429581 SLC5A6 transports vitamins from extracellular region to cytosol TAS Homo sapiens 4787 R-HSA-9035987 https://reactome.org/PathwayBrowser/#/R-HSA-9035987 Defective HLCS does not biotinylate 6xMCCC1:6xMCCC2 TAS Homo sapiens 4787 R-HSA-9035988 https://reactome.org/PathwayBrowser/#/R-HSA-9035988 Defective HLCS does not biotinylate PC:Mn2+ TAS Homo sapiens 4787 R-HSA-9035990 https://reactome.org/PathwayBrowser/#/R-HSA-9035990 Defective HLCS does not biotinylate 6x(PCCA:PCCB) TAS Homo sapiens 4787 R-MMU-199219 https://reactome.org/PathwayBrowser/#/R-MMU-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Mus musculus 4787 R-MMU-2993447 https://reactome.org/PathwayBrowser/#/R-MMU-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Mus musculus 4787 R-MMU-2993799 https://reactome.org/PathwayBrowser/#/R-MMU-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Mus musculus 4787 R-MMU-2993802 https://reactome.org/PathwayBrowser/#/R-MMU-2993802 HLCS biotinylates PC:Mn2+ IEA Mus musculus 4787 R-MMU-2993814 https://reactome.org/PathwayBrowser/#/R-MMU-2993814 HLCS biotinylates ACACA:Mn2+ IEA Mus musculus 4787 R-MMU-3076905 https://reactome.org/PathwayBrowser/#/R-MMU-3076905 Extracellular BTD hydrolyses BCTN IEA Mus musculus 4787 R-MMU-4167509 https://reactome.org/PathwayBrowser/#/R-MMU-4167509 Mitochondrial BTD hydrolyses BCTN IEA Mus musculus 4787 R-MMU-4167511 https://reactome.org/PathwayBrowser/#/R-MMU-4167511 HLCS biotinylates ACACB IEA Mus musculus 4787 R-MMU-429581 https://reactome.org/PathwayBrowser/#/R-MMU-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Mus musculus 4787 R-PFA-2993814 https://reactome.org/PathwayBrowser/#/R-PFA-2993814 HLCS biotinylates ACACA:Mn2+ IEA Plasmodium falciparum 4787 R-PFA-4167511 https://reactome.org/PathwayBrowser/#/R-PFA-4167511 HLCS biotinylates ACACB IEA Plasmodium falciparum 4787 R-RNO-199219 https://reactome.org/PathwayBrowser/#/R-RNO-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Rattus norvegicus 4787 R-RNO-2993447 https://reactome.org/PathwayBrowser/#/R-RNO-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Rattus norvegicus 4787 R-RNO-2993799 https://reactome.org/PathwayBrowser/#/R-RNO-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Rattus norvegicus 4787 R-RNO-2993802 https://reactome.org/PathwayBrowser/#/R-RNO-2993802 HLCS biotinylates PC:Mn2+ IEA Rattus norvegicus 4787 R-RNO-2993814 https://reactome.org/PathwayBrowser/#/R-RNO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Rattus norvegicus 4787 R-RNO-3076905 https://reactome.org/PathwayBrowser/#/R-RNO-3076905 Extracellular BTD hydrolyses BCTN IEA Rattus norvegicus 4787 R-RNO-4167509 https://reactome.org/PathwayBrowser/#/R-RNO-4167509 Mitochondrial BTD hydrolyses BCTN IEA Rattus norvegicus 4787 R-RNO-4167511 https://reactome.org/PathwayBrowser/#/R-RNO-4167511 HLCS biotinylates ACACB IEA Rattus norvegicus 4787 R-RNO-429581 https://reactome.org/PathwayBrowser/#/R-RNO-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Rattus norvegicus 4787 R-SCE-2993802 https://reactome.org/PathwayBrowser/#/R-SCE-2993802 HLCS biotinylates PC:Mn2+ IEA Saccharomyces cerevisiae 4787 R-SCE-2993814 https://reactome.org/PathwayBrowser/#/R-SCE-2993814 HLCS biotinylates ACACA:Mn2+ IEA Saccharomyces cerevisiae 4787 R-SCE-4167511 https://reactome.org/PathwayBrowser/#/R-SCE-4167511 HLCS biotinylates ACACB IEA Saccharomyces cerevisiae 4787 R-SPO-2993802 https://reactome.org/PathwayBrowser/#/R-SPO-2993802 HLCS biotinylates PC:Mn2+ IEA Schizosaccharomyces pombe 4787 R-SPO-2993814 https://reactome.org/PathwayBrowser/#/R-SPO-2993814 HLCS biotinylates ACACA:Mn2+ IEA Schizosaccharomyces pombe 4787 R-SPO-4167511 https://reactome.org/PathwayBrowser/#/R-SPO-4167511 HLCS biotinylates ACACB IEA Schizosaccharomyces pombe 4787 R-SSC-199219 https://reactome.org/PathwayBrowser/#/R-SSC-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Sus scrofa 4787 R-SSC-2993447 https://reactome.org/PathwayBrowser/#/R-SSC-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Sus scrofa 4787 R-SSC-2993799 https://reactome.org/PathwayBrowser/#/R-SSC-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Sus scrofa 4787 R-SSC-2993802 https://reactome.org/PathwayBrowser/#/R-SSC-2993802 HLCS biotinylates PC:Mn2+ IEA Sus scrofa 4787 R-SSC-2993814 https://reactome.org/PathwayBrowser/#/R-SSC-2993814 HLCS biotinylates ACACA:Mn2+ IEA Sus scrofa 4787 R-SSC-3076905 https://reactome.org/PathwayBrowser/#/R-SSC-3076905 Extracellular BTD hydrolyses BCTN IEA Sus scrofa 4787 R-SSC-4167509 https://reactome.org/PathwayBrowser/#/R-SSC-4167509 Mitochondrial BTD hydrolyses BCTN IEA Sus scrofa 4787 R-SSC-4167511 https://reactome.org/PathwayBrowser/#/R-SSC-4167511 HLCS biotinylates ACACB IEA Sus scrofa 4787 R-SSC-429581 https://reactome.org/PathwayBrowser/#/R-SSC-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Sus scrofa 4787 R-XTR-199219 https://reactome.org/PathwayBrowser/#/R-XTR-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol IEA Xenopus tropicalis 4787 R-XTR-2993447 https://reactome.org/PathwayBrowser/#/R-XTR-2993447 HLCS biotinylates 6x(PCCA:PCCB) IEA Xenopus tropicalis 4787 R-XTR-2993799 https://reactome.org/PathwayBrowser/#/R-XTR-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 IEA Xenopus tropicalis 4787 R-XTR-2993802 https://reactome.org/PathwayBrowser/#/R-XTR-2993802 HLCS biotinylates PC:Mn2+ IEA Xenopus tropicalis 4787 R-XTR-2993814 https://reactome.org/PathwayBrowser/#/R-XTR-2993814 HLCS biotinylates ACACA:Mn2+ IEA Xenopus tropicalis 4787 R-XTR-3076905 https://reactome.org/PathwayBrowser/#/R-XTR-3076905 Extracellular BTD hydrolyses BCTN IEA Xenopus tropicalis 4787 R-XTR-4167509 https://reactome.org/PathwayBrowser/#/R-XTR-4167509 Mitochondrial BTD hydrolyses BCTN IEA Xenopus tropicalis 4787 R-XTR-4167511 https://reactome.org/PathwayBrowser/#/R-XTR-4167511 HLCS biotinylates ACACB IEA Xenopus tropicalis 4787 R-XTR-429581 https://reactome.org/PathwayBrowser/#/R-XTR-429581 SLC5A6 transports vitamins from extracellular region to cytosol IEA Xenopus tropicalis 4788 R-BTA-109527 https://reactome.org/PathwayBrowser/#/R-BTA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4788 R-BTA-109529 https://reactome.org/PathwayBrowser/#/R-BTA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Bos taurus 4788 R-BTA-110246 https://reactome.org/PathwayBrowser/#/R-BTA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Bos taurus 4788 R-BTA-1237160 https://reactome.org/PathwayBrowser/#/R-BTA-1237160 MTA is cleaved and phosphorylated IEA Bos taurus 4788 R-BTA-727749 https://reactome.org/PathwayBrowser/#/R-BTA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Bos taurus 4788 R-BTA-727767 https://reactome.org/PathwayBrowser/#/R-BTA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Bos taurus 4788 R-BTA-74213 https://reactome.org/PathwayBrowser/#/R-BTA-74213 APRT catalyzes the conversion of adenine to AMP IEA Bos taurus 4788 R-CEL-109527 https://reactome.org/PathwayBrowser/#/R-CEL-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4788 R-CEL-109529 https://reactome.org/PathwayBrowser/#/R-CEL-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Caenorhabditis elegans 4788 R-CEL-1237160 https://reactome.org/PathwayBrowser/#/R-CEL-1237160 MTA is cleaved and phosphorylated IEA Caenorhabditis elegans 4788 R-CEL-727749 https://reactome.org/PathwayBrowser/#/R-CEL-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Caenorhabditis elegans 4788 R-CEL-727767 https://reactome.org/PathwayBrowser/#/R-CEL-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 4788 R-CEL-74213 https://reactome.org/PathwayBrowser/#/R-CEL-74213 APRT catalyzes the conversion of adenine to AMP IEA Caenorhabditis elegans 4788 R-CFA-109527 https://reactome.org/PathwayBrowser/#/R-CFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4788 R-CFA-109529 https://reactome.org/PathwayBrowser/#/R-CFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Canis familiaris 4788 R-CFA-110246 https://reactome.org/PathwayBrowser/#/R-CFA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Canis familiaris 4788 R-CFA-1237160 https://reactome.org/PathwayBrowser/#/R-CFA-1237160 MTA is cleaved and phosphorylated IEA Canis familiaris 4788 R-CFA-727749 https://reactome.org/PathwayBrowser/#/R-CFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Canis familiaris 4788 R-CFA-727767 https://reactome.org/PathwayBrowser/#/R-CFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Canis familiaris 4788 R-CFA-74213 https://reactome.org/PathwayBrowser/#/R-CFA-74213 APRT catalyzes the conversion of adenine to AMP IEA Canis familiaris 4788 R-DDI-109527 https://reactome.org/PathwayBrowser/#/R-DDI-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4788 R-DDI-109529 https://reactome.org/PathwayBrowser/#/R-DDI-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Dictyostelium discoideum 4788 R-DDI-110246 https://reactome.org/PathwayBrowser/#/R-DDI-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Dictyostelium discoideum 4788 R-DDI-727749 https://reactome.org/PathwayBrowser/#/R-DDI-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Dictyostelium discoideum 4788 R-DDI-727767 https://reactome.org/PathwayBrowser/#/R-DDI-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Dictyostelium discoideum 4788 R-DME-109527 https://reactome.org/PathwayBrowser/#/R-DME-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4788 R-DME-109529 https://reactome.org/PathwayBrowser/#/R-DME-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Drosophila melanogaster 4788 R-DME-1237160 https://reactome.org/PathwayBrowser/#/R-DME-1237160 MTA is cleaved and phosphorylated IEA Drosophila melanogaster 4788 R-DME-727749 https://reactome.org/PathwayBrowser/#/R-DME-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Drosophila melanogaster 4788 R-DME-727767 https://reactome.org/PathwayBrowser/#/R-DME-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Drosophila melanogaster 4788 R-DME-74213 https://reactome.org/PathwayBrowser/#/R-DME-74213 APRT catalyzes the conversion of adenine to AMP IEA Drosophila melanogaster 4788 R-DRE-1237160 https://reactome.org/PathwayBrowser/#/R-DRE-1237160 MTA is cleaved and phosphorylated IEA Danio rerio 4788 R-DRE-74213 https://reactome.org/PathwayBrowser/#/R-DRE-74213 APRT catalyzes the conversion of adenine to AMP IEA Danio rerio 4788 R-GGA-110246 https://reactome.org/PathwayBrowser/#/R-GGA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Gallus gallus 4788 R-GGA-1237160 https://reactome.org/PathwayBrowser/#/R-GGA-1237160 MTA is cleaved and phosphorylated IEA Gallus gallus 4788 R-GGA-727749 https://reactome.org/PathwayBrowser/#/R-GGA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Gallus gallus 4788 R-GGA-727767 https://reactome.org/PathwayBrowser/#/R-GGA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Gallus gallus 4788 R-GGA-74213 https://reactome.org/PathwayBrowser/#/R-GGA-74213 APRT catalyzes the conversion of adenine to AMP IEA Gallus gallus 4788 R-HSA-109527 https://reactome.org/PathwayBrowser/#/R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4788 R-HSA-109529 https://reactome.org/PathwayBrowser/#/R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 TAS Homo sapiens 4788 R-HSA-110246 https://reactome.org/PathwayBrowser/#/R-HSA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH TAS Homo sapiens 4788 R-HSA-1237160 https://reactome.org/PathwayBrowser/#/R-HSA-1237160 MTA is cleaved and phosphorylated TAS Homo sapiens 4788 R-HSA-5628807 https://reactome.org/PathwayBrowser/#/R-HSA-5628807 Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4788 R-HSA-727749 https://reactome.org/PathwayBrowser/#/R-HSA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol TAS Homo sapiens 4788 R-HSA-727767 https://reactome.org/PathwayBrowser/#/R-HSA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen TAS Homo sapiens 4788 R-HSA-74213 https://reactome.org/PathwayBrowser/#/R-HSA-74213 APRT catalyzes the conversion of adenine to AMP TAS Homo sapiens 4788 R-HSA-9734193 https://reactome.org/PathwayBrowser/#/R-HSA-9734193 Defective APRT does not convert adenine to AMP TAS Homo sapiens 4788 R-MMU-109527 https://reactome.org/PathwayBrowser/#/R-MMU-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4788 R-MMU-109529 https://reactome.org/PathwayBrowser/#/R-MMU-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Mus musculus 4788 R-MMU-110246 https://reactome.org/PathwayBrowser/#/R-MMU-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Mus musculus 4788 R-MMU-1237160 https://reactome.org/PathwayBrowser/#/R-MMU-1237160 MTA is cleaved and phosphorylated IEA Mus musculus 4788 R-MMU-727749 https://reactome.org/PathwayBrowser/#/R-MMU-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Mus musculus 4788 R-MMU-727767 https://reactome.org/PathwayBrowser/#/R-MMU-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Mus musculus 4788 R-MMU-74213 https://reactome.org/PathwayBrowser/#/R-MMU-74213 APRT catalyzes the conversion of adenine to AMP IEA Mus musculus 4788 R-NUL-9635966 https://reactome.org/PathwayBrowser/#/R-NUL-9635966 Mutyh cleaves adenine mispaired with 8-oxoguanine TAS Mus musculus 4788 R-PFA-109527 https://reactome.org/PathwayBrowser/#/R-PFA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4788 R-PFA-109529 https://reactome.org/PathwayBrowser/#/R-PFA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Plasmodium falciparum 4788 R-PFA-110246 https://reactome.org/PathwayBrowser/#/R-PFA-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Plasmodium falciparum 4788 R-PFA-727749 https://reactome.org/PathwayBrowser/#/R-PFA-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Plasmodium falciparum 4788 R-PFA-727767 https://reactome.org/PathwayBrowser/#/R-PFA-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Plasmodium falciparum 4788 R-RNO-109527 https://reactome.org/PathwayBrowser/#/R-RNO-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4788 R-RNO-109529 https://reactome.org/PathwayBrowser/#/R-RNO-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Rattus norvegicus 4788 R-RNO-110246 https://reactome.org/PathwayBrowser/#/R-RNO-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Rattus norvegicus 4788 R-RNO-1237160 https://reactome.org/PathwayBrowser/#/R-RNO-1237160 MTA is cleaved and phosphorylated IEA Rattus norvegicus 4788 R-RNO-727749 https://reactome.org/PathwayBrowser/#/R-RNO-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Rattus norvegicus 4788 R-RNO-727767 https://reactome.org/PathwayBrowser/#/R-RNO-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Rattus norvegicus 4788 R-RNO-74213 https://reactome.org/PathwayBrowser/#/R-RNO-74213 APRT catalyzes the conversion of adenine to AMP IEA Rattus norvegicus 4788 R-SCE-1237160 https://reactome.org/PathwayBrowser/#/R-SCE-1237160 MTA is cleaved and phosphorylated IEA Saccharomyces cerevisiae 4788 R-SCE-74213 https://reactome.org/PathwayBrowser/#/R-SCE-74213 APRT catalyzes the conversion of adenine to AMP IEA Saccharomyces cerevisiae 4788 R-SPO-110246 https://reactome.org/PathwayBrowser/#/R-SPO-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Schizosaccharomyces pombe 4788 R-SPO-1237160 https://reactome.org/PathwayBrowser/#/R-SPO-1237160 MTA is cleaved and phosphorylated IEA Schizosaccharomyces pombe 4788 R-SPO-74213 https://reactome.org/PathwayBrowser/#/R-SPO-74213 APRT catalyzes the conversion of adenine to AMP IEA Schizosaccharomyces pombe 4788 R-SSC-109527 https://reactome.org/PathwayBrowser/#/R-SSC-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4788 R-SSC-109529 https://reactome.org/PathwayBrowser/#/R-SSC-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 IEA Sus scrofa 4788 R-SSC-110246 https://reactome.org/PathwayBrowser/#/R-SSC-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Sus scrofa 4788 R-SSC-1237160 https://reactome.org/PathwayBrowser/#/R-SSC-1237160 MTA is cleaved and phosphorylated IEA Sus scrofa 4788 R-SSC-727749 https://reactome.org/PathwayBrowser/#/R-SSC-727749 SLC29A3 transports nucleosides from lysosomal lumen to cytosol IEA Sus scrofa 4788 R-SSC-727767 https://reactome.org/PathwayBrowser/#/R-SSC-727767 SLC29A3 transports nucleosides from cytosol to lysosomal lumen IEA Sus scrofa 4788 R-SSC-74213 https://reactome.org/PathwayBrowser/#/R-SSC-74213 APRT catalyzes the conversion of adenine to AMP IEA Sus scrofa 4788 R-XTR-110246 https://reactome.org/PathwayBrowser/#/R-XTR-110246 Cleavage of adenine mispaired with 8-oxoguanine by MUTYH IEA Xenopus tropicalis 4788 R-XTR-1237160 https://reactome.org/PathwayBrowser/#/R-XTR-1237160 MTA is cleaved and phosphorylated IEA Xenopus tropicalis 4788 R-XTR-74213 https://reactome.org/PathwayBrowser/#/R-XTR-74213 APRT catalyzes the conversion of adenine to AMP IEA Xenopus tropicalis 4790 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 4790 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 4790 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 4790 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 4790 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 4790 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 4790 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 4790 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 4790 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 4790 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 4790 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 4790 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 4795 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 4795 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 4795 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 4795 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 4795 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 4795 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 4795 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 4795 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 4795 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 4795 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 4795 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 4795 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 4795 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 4795 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 4795 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 4795 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 4795 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 4795 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 4796 R-HSA-9911461 https://reactome.org/PathwayBrowser/#/R-HSA-9911461 β-lactam antibiotics bind MrcB TAS Homo sapiens 4796 R-HSA-9911463 https://reactome.org/PathwayBrowser/#/R-HSA-9911463 MrcB elongates peptidoglycan TAS Homo sapiens 4796 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 4796 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 4796 R-HSA-9911518 https://reactome.org/PathwayBrowser/#/R-HSA-9911518 OXA-9 hydrolyzes penicillin G TAS Homo sapiens 4796 R-HSA-9911520 https://reactome.org/PathwayBrowser/#/R-HSA-9911520 TEM-1 hydrolyzes penicillin G TAS Homo sapiens 4796 R-HSA-9914083 https://reactome.org/PathwayBrowser/#/R-HSA-9914083 MdtE:MdtF:TolC exports beta-lactams to extracellular space TAS Homo sapiens 4796 R-HSA-9914089 https://reactome.org/PathwayBrowser/#/R-HSA-9914089 MdtE:MdtF:TolC exports beta-lactams to the periplasm TAS Homo sapiens 4797 R-BTA-9714580 https://reactome.org/PathwayBrowser/#/R-BTA-9714580 SLC6A3 binds DRIs IEA Bos taurus 4797 R-CEL-9714580 https://reactome.org/PathwayBrowser/#/R-CEL-9714580 SLC6A3 binds DRIs IEA Caenorhabditis elegans 4797 R-CFA-9714580 https://reactome.org/PathwayBrowser/#/R-CFA-9714580 SLC6A3 binds DRIs IEA Canis familiaris 4797 R-DME-9714580 https://reactome.org/PathwayBrowser/#/R-DME-9714580 SLC6A3 binds DRIs IEA Drosophila melanogaster 4797 R-DRE-9714580 https://reactome.org/PathwayBrowser/#/R-DRE-9714580 SLC6A3 binds DRIs IEA Danio rerio 4797 R-HSA-9714580 https://reactome.org/PathwayBrowser/#/R-HSA-9714580 SLC6A3 binds DRIs TAS Homo sapiens 4797 R-MMU-9714580 https://reactome.org/PathwayBrowser/#/R-MMU-9714580 SLC6A3 binds DRIs IEA Mus musculus 4797 R-PFA-9714580 https://reactome.org/PathwayBrowser/#/R-PFA-9714580 SLC6A3 binds DRIs IEA Plasmodium falciparum 4797 R-RNO-9714580 https://reactome.org/PathwayBrowser/#/R-RNO-9714580 SLC6A3 binds DRIs IEA Rattus norvegicus 4797 R-SSC-9714580 https://reactome.org/PathwayBrowser/#/R-SSC-9714580 SLC6A3 binds DRIs IEA Sus scrofa 4797 R-XTR-9714580 https://reactome.org/PathwayBrowser/#/R-XTR-9714580 SLC6A3 binds DRIs IEA Xenopus tropicalis 4798 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 4798 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 4798 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 4798 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 4798 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 4798 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 4798 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 4798 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 4798 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 4798 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 4798 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 4798 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 48 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 48 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 48 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 48 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 48 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 48 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 48 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 48 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 48 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 48 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 480 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 480 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 480 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 480 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 480 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 480 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 480 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 480 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 480 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 480 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 480 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 480 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 480 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 480 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 480 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 480 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 480 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 480 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 480 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 480 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 480 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 480 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 481 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 481 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 481 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 481 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 481 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 481 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 481 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 481 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 481 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 481 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 481 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 481 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 481 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 481 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 481 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 481 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 481 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 481 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 481 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 481 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 481 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 481 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 4812 R-BTA-2022403 https://reactome.org/PathwayBrowser/#/R-BTA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Bos taurus 4812 R-BTA-2022412 https://reactome.org/PathwayBrowser/#/R-BTA-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Bos taurus 4812 R-BTA-2065357 https://reactome.org/PathwayBrowser/#/R-BTA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Bos taurus 4812 R-CEL-2022403 https://reactome.org/PathwayBrowser/#/R-CEL-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Caenorhabditis elegans 4812 R-CEL-2022412 https://reactome.org/PathwayBrowser/#/R-CEL-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Caenorhabditis elegans 4812 R-CEL-2065357 https://reactome.org/PathwayBrowser/#/R-CEL-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Caenorhabditis elegans 4812 R-CFA-2022403 https://reactome.org/PathwayBrowser/#/R-CFA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Canis familiaris 4812 R-CFA-2022412 https://reactome.org/PathwayBrowser/#/R-CFA-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Canis familiaris 4812 R-CFA-2065357 https://reactome.org/PathwayBrowser/#/R-CFA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Canis familiaris 4812 R-DME-2022403 https://reactome.org/PathwayBrowser/#/R-DME-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Drosophila melanogaster 4812 R-DME-2022412 https://reactome.org/PathwayBrowser/#/R-DME-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Drosophila melanogaster 4812 R-DME-2065357 https://reactome.org/PathwayBrowser/#/R-DME-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Drosophila melanogaster 4812 R-DRE-2022412 https://reactome.org/PathwayBrowser/#/R-DRE-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Danio rerio 4812 R-GGA-2022403 https://reactome.org/PathwayBrowser/#/R-GGA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Gallus gallus 4812 R-GGA-2022412 https://reactome.org/PathwayBrowser/#/R-GGA-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Gallus gallus 4812 R-GGA-2065357 https://reactome.org/PathwayBrowser/#/R-GGA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Gallus gallus 4812 R-HSA-2022403 https://reactome.org/PathwayBrowser/#/R-HSA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) TAS Homo sapiens 4812 R-HSA-2022412 https://reactome.org/PathwayBrowser/#/R-HSA-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) TAS Homo sapiens 4812 R-HSA-2065357 https://reactome.org/PathwayBrowser/#/R-HSA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) TAS Homo sapiens 4812 R-MMU-2022403 https://reactome.org/PathwayBrowser/#/R-MMU-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Mus musculus 4812 R-MMU-2022412 https://reactome.org/PathwayBrowser/#/R-MMU-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Mus musculus 4812 R-MMU-2065357 https://reactome.org/PathwayBrowser/#/R-MMU-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Mus musculus 4812 R-RNO-2022403 https://reactome.org/PathwayBrowser/#/R-RNO-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Rattus norvegicus 4812 R-RNO-2022412 https://reactome.org/PathwayBrowser/#/R-RNO-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Rattus norvegicus 4812 R-RNO-2065357 https://reactome.org/PathwayBrowser/#/R-RNO-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Rattus norvegicus 4812 R-SSC-2022403 https://reactome.org/PathwayBrowser/#/R-SSC-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Sus scrofa 4812 R-SSC-2022412 https://reactome.org/PathwayBrowser/#/R-SSC-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Sus scrofa 4812 R-SSC-2065357 https://reactome.org/PathwayBrowser/#/R-SSC-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Sus scrofa 4812 R-XTR-2022403 https://reactome.org/PathwayBrowser/#/R-XTR-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Xenopus tropicalis 4812 R-XTR-2022412 https://reactome.org/PathwayBrowser/#/R-XTR-2022412 Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) IEA Xenopus tropicalis 4812 R-XTR-2065357 https://reactome.org/PathwayBrowser/#/R-XTR-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to AGT(25-35) (Angiotensin-(1-10)) IEA Xenopus tropicalis 4815 R-BTA-9709109 https://reactome.org/PathwayBrowser/#/R-BTA-9709109 DHFR dimer binds DHFR inhibitors IEA Bos taurus 4815 R-CEL-9709109 https://reactome.org/PathwayBrowser/#/R-CEL-9709109 DHFR dimer binds DHFR inhibitors IEA Caenorhabditis elegans 4815 R-CFA-9709109 https://reactome.org/PathwayBrowser/#/R-CFA-9709109 DHFR dimer binds DHFR inhibitors IEA Canis familiaris 4815 R-DDI-9709109 https://reactome.org/PathwayBrowser/#/R-DDI-9709109 DHFR dimer binds DHFR inhibitors IEA Dictyostelium discoideum 4815 R-DME-9709109 https://reactome.org/PathwayBrowser/#/R-DME-9709109 DHFR dimer binds DHFR inhibitors IEA Drosophila melanogaster 4815 R-DRE-9709109 https://reactome.org/PathwayBrowser/#/R-DRE-9709109 DHFR dimer binds DHFR inhibitors IEA Danio rerio 4815 R-GGA-9709109 https://reactome.org/PathwayBrowser/#/R-GGA-9709109 DHFR dimer binds DHFR inhibitors IEA Gallus gallus 4815 R-HSA-9709109 https://reactome.org/PathwayBrowser/#/R-HSA-9709109 DHFR dimer binds DHFR inhibitors TAS Homo sapiens 4815 R-MMU-9709109 https://reactome.org/PathwayBrowser/#/R-MMU-9709109 DHFR dimer binds DHFR inhibitors IEA Mus musculus 4815 R-RNO-9709109 https://reactome.org/PathwayBrowser/#/R-RNO-9709109 DHFR dimer binds DHFR inhibitors IEA Rattus norvegicus 4815 R-SCE-9709109 https://reactome.org/PathwayBrowser/#/R-SCE-9709109 DHFR dimer binds DHFR inhibitors IEA Saccharomyces cerevisiae 4815 R-SPO-9709109 https://reactome.org/PathwayBrowser/#/R-SPO-9709109 DHFR dimer binds DHFR inhibitors IEA Schizosaccharomyces pombe 4815 R-SSC-9709109 https://reactome.org/PathwayBrowser/#/R-SSC-9709109 DHFR dimer binds DHFR inhibitors IEA Sus scrofa 4819 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 4819 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 4819 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 4819 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 4819 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 4819 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 4819 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 4819 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 4820 R-BTA-9677320 https://reactome.org/PathwayBrowser/#/R-BTA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Bos taurus 4820 R-CFA-9677320 https://reactome.org/PathwayBrowser/#/R-CFA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Canis familiaris 4820 R-DRE-9677320 https://reactome.org/PathwayBrowser/#/R-DRE-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Danio rerio 4820 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus 4820 R-HSA-9677320 https://reactome.org/PathwayBrowser/#/R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors TAS Homo sapiens 4820 R-MMU-9677320 https://reactome.org/PathwayBrowser/#/R-MMU-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Mus musculus 4820 R-RNO-9677320 https://reactome.org/PathwayBrowser/#/R-RNO-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Rattus norvegicus 4820 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa 4820 R-XTR-9677320 https://reactome.org/PathwayBrowser/#/R-XTR-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Xenopus tropicalis 4826 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 4826 R-BTA-9684068 https://reactome.org/PathwayBrowser/#/R-BTA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Bos taurus 4826 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 4826 R-CFA-9684068 https://reactome.org/PathwayBrowser/#/R-CFA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Canis familiaris 4826 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 4826 R-DRE-9684068 https://reactome.org/PathwayBrowser/#/R-DRE-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Danio rerio 4826 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 4826 R-GGA-9684068 https://reactome.org/PathwayBrowser/#/R-GGA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Gallus gallus 4826 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 4826 R-HSA-9684068 https://reactome.org/PathwayBrowser/#/R-HSA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides TAS Homo sapiens 4826 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 4826 R-MMU-9684068 https://reactome.org/PathwayBrowser/#/R-MMU-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Mus musculus 4826 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 4826 R-RNO-9684068 https://reactome.org/PathwayBrowser/#/R-RNO-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Rattus norvegicus 4826 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 4826 R-SSC-9684068 https://reactome.org/PathwayBrowser/#/R-SSC-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Sus scrofa 4826 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 4826 R-XTR-9684068 https://reactome.org/PathwayBrowser/#/R-XTR-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Xenopus tropicalis 483 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 483 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 483 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 483 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 483 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 483 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 483 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 483 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 483 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 483 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 483 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 483 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 483 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 483 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 483 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 483 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 483 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 483 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 483 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 483 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 483 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 483 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 4835 R-BTA-9725706 https://reactome.org/PathwayBrowser/#/R-BTA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Bos taurus 4835 R-CEL-9725706 https://reactome.org/PathwayBrowser/#/R-CEL-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Caenorhabditis elegans 4835 R-CFA-9725706 https://reactome.org/PathwayBrowser/#/R-CFA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Canis familiaris 4835 R-DME-9725706 https://reactome.org/PathwayBrowser/#/R-DME-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Drosophila melanogaster 4835 R-HSA-9725706 https://reactome.org/PathwayBrowser/#/R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors TAS Homo sapiens 4835 R-MMU-9725706 https://reactome.org/PathwayBrowser/#/R-MMU-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Mus musculus 4835 R-RNO-9725706 https://reactome.org/PathwayBrowser/#/R-RNO-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Rattus norvegicus 4835 R-SSC-9725706 https://reactome.org/PathwayBrowser/#/R-SSC-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Sus scrofa 4835 R-XTR-9725706 https://reactome.org/PathwayBrowser/#/R-XTR-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Xenopus tropicalis 4836 R-BTA-9725706 https://reactome.org/PathwayBrowser/#/R-BTA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Bos taurus 4836 R-CEL-9725706 https://reactome.org/PathwayBrowser/#/R-CEL-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Caenorhabditis elegans 4836 R-CFA-9725706 https://reactome.org/PathwayBrowser/#/R-CFA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Canis familiaris 4836 R-DME-9725706 https://reactome.org/PathwayBrowser/#/R-DME-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Drosophila melanogaster 4836 R-HSA-9725706 https://reactome.org/PathwayBrowser/#/R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors TAS Homo sapiens 4836 R-MMU-9725706 https://reactome.org/PathwayBrowser/#/R-MMU-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Mus musculus 4836 R-RNO-9725706 https://reactome.org/PathwayBrowser/#/R-RNO-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Rattus norvegicus 4836 R-SSC-9725706 https://reactome.org/PathwayBrowser/#/R-SSC-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Sus scrofa 4836 R-XTR-9725706 https://reactome.org/PathwayBrowser/#/R-XTR-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Xenopus tropicalis 4838 R-BTA-9725706 https://reactome.org/PathwayBrowser/#/R-BTA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Bos taurus 4838 R-CEL-9725706 https://reactome.org/PathwayBrowser/#/R-CEL-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Caenorhabditis elegans 4838 R-CFA-9725706 https://reactome.org/PathwayBrowser/#/R-CFA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Canis familiaris 4838 R-DME-9725706 https://reactome.org/PathwayBrowser/#/R-DME-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Drosophila melanogaster 4838 R-HSA-9725706 https://reactome.org/PathwayBrowser/#/R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors TAS Homo sapiens 4838 R-MMU-9725706 https://reactome.org/PathwayBrowser/#/R-MMU-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Mus musculus 4838 R-RNO-9725706 https://reactome.org/PathwayBrowser/#/R-RNO-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Rattus norvegicus 4838 R-SSC-9725706 https://reactome.org/PathwayBrowser/#/R-SSC-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Sus scrofa 4838 R-XTR-9725706 https://reactome.org/PathwayBrowser/#/R-XTR-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Xenopus tropicalis 4840 R-BTA-9707186 https://reactome.org/PathwayBrowser/#/R-BTA-9707186 ALOX5 binds ALOX5 inhibitors IEA Bos taurus 4840 R-CFA-9707186 https://reactome.org/PathwayBrowser/#/R-CFA-9707186 ALOX5 binds ALOX5 inhibitors IEA Canis familiaris 4840 R-DDI-9707186 https://reactome.org/PathwayBrowser/#/R-DDI-9707186 ALOX5 binds ALOX5 inhibitors IEA Dictyostelium discoideum 4840 R-GGA-9707186 https://reactome.org/PathwayBrowser/#/R-GGA-9707186 ALOX5 binds ALOX5 inhibitors IEA Gallus gallus 4840 R-HSA-9707186 https://reactome.org/PathwayBrowser/#/R-HSA-9707186 ALOX5 binds ALOX5 inhibitors TAS Homo sapiens 4840 R-MMU-9707186 https://reactome.org/PathwayBrowser/#/R-MMU-9707186 ALOX5 binds ALOX5 inhibitors IEA Mus musculus 4840 R-RNO-9707186 https://reactome.org/PathwayBrowser/#/R-RNO-9707186 ALOX5 binds ALOX5 inhibitors IEA Rattus norvegicus 4840 R-SSC-9707186 https://reactome.org/PathwayBrowser/#/R-SSC-9707186 ALOX5 binds ALOX5 inhibitors IEA Sus scrofa 4840 R-XTR-9707186 https://reactome.org/PathwayBrowser/#/R-XTR-9707186 ALOX5 binds ALOX5 inhibitors IEA Xenopus tropicalis 4841 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 4841 R-HSA-9686790 https://reactome.org/PathwayBrowser/#/R-HSA-9686790 ER-alpha glucosidases bind ER-alpha glucosidase inhibitors TAS Homo sapiens 4841 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 4842 R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 4842 R-HSA-9686790 https://reactome.org/PathwayBrowser/#/R-HSA-9686790 ER-alpha glucosidases bind ER-alpha glucosidase inhibitors TAS Homo sapiens 4842 R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 485 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 485 R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 485 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 485 R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 485 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 485 R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 485 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 485 R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 485 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 485 R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 485 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 485 R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 485 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 485 R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 485 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 485 R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 485 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 485 R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 485 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 485 R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 485 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 485 R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 4860 R-BTA-9714924 https://reactome.org/PathwayBrowser/#/R-BTA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Bos taurus 4860 R-BTA-9714959 https://reactome.org/PathwayBrowser/#/R-BTA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Bos taurus 4860 R-CFA-9714924 https://reactome.org/PathwayBrowser/#/R-CFA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Canis familiaris 4860 R-CFA-9714959 https://reactome.org/PathwayBrowser/#/R-CFA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Canis familiaris 4860 R-DRE-9714924 https://reactome.org/PathwayBrowser/#/R-DRE-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Danio rerio 4860 R-DRE-9714959 https://reactome.org/PathwayBrowser/#/R-DRE-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Danio rerio 4860 R-HSA-9714924 https://reactome.org/PathwayBrowser/#/R-HSA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer TAS Homo sapiens 4860 R-HSA-9714959 https://reactome.org/PathwayBrowser/#/R-HSA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer TAS Homo sapiens 4860 R-MMU-9714924 https://reactome.org/PathwayBrowser/#/R-MMU-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Mus musculus 4860 R-MMU-9714959 https://reactome.org/PathwayBrowser/#/R-MMU-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Mus musculus 4860 R-RNO-9714924 https://reactome.org/PathwayBrowser/#/R-RNO-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Rattus norvegicus 4860 R-RNO-9714959 https://reactome.org/PathwayBrowser/#/R-RNO-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Rattus norvegicus 4860 R-SSC-9714924 https://reactome.org/PathwayBrowser/#/R-SSC-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Sus scrofa 4860 R-SSC-9714959 https://reactome.org/PathwayBrowser/#/R-SSC-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Sus scrofa 4860 R-XTR-9714924 https://reactome.org/PathwayBrowser/#/R-XTR-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Xenopus tropicalis 4860 R-XTR-9714959 https://reactome.org/PathwayBrowser/#/R-XTR-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Xenopus tropicalis 4903 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 4903 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 4903 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 4903 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 4903 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 4903 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 4903 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 4903 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 4903 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 4903 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 4903 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 4903 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 4903 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 4903 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 4903 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 4903 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 4903 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 4903 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 4903 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 4903 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 4903 R-HSA-9715357 https://reactome.org/PathwayBrowser/#/R-HSA-9715357 crizotinib-resistant ALK mutants don't bind crizotinib TAS Homo sapiens 4903 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 4903 R-HSA-9851068 https://reactome.org/PathwayBrowser/#/R-HSA-9851068 Crizotinib-driven IL10RA gene expression in NPM1-ALK TAS Homo sapiens 4903 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 4903 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 4903 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 4903 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 4903 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 4903 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 4903 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 4903 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 4903 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 4903 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 4903 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 4903 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 4903 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 4903 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 4920 R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 4921 R-BTA-9709454 https://reactome.org/PathwayBrowser/#/R-BTA-9709454 EPOR binds EPOR agonists IEA Bos taurus 4921 R-CFA-9709454 https://reactome.org/PathwayBrowser/#/R-CFA-9709454 EPOR binds EPOR agonists IEA Canis familiaris 4921 R-DME-9709454 https://reactome.org/PathwayBrowser/#/R-DME-9709454 EPOR binds EPOR agonists IEA Drosophila melanogaster 4921 R-HSA-9709454 https://reactome.org/PathwayBrowser/#/R-HSA-9709454 EPOR binds EPOR agonists TAS Homo sapiens 4921 R-MMU-9709454 https://reactome.org/PathwayBrowser/#/R-MMU-9709454 EPOR binds EPOR agonists IEA Mus musculus 4921 R-RNO-9709454 https://reactome.org/PathwayBrowser/#/R-RNO-9709454 EPOR binds EPOR agonists IEA Rattus norvegicus 4921 R-SSC-9709454 https://reactome.org/PathwayBrowser/#/R-SSC-9709454 EPOR binds EPOR agonists IEA Sus scrofa 4921 R-XTR-9709454 https://reactome.org/PathwayBrowser/#/R-XTR-9709454 EPOR binds EPOR agonists IEA Xenopus tropicalis 4941 R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 4941 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 4941 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 4960 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 4960 R-BTA-9696179 https://reactome.org/PathwayBrowser/#/R-BTA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Bos taurus 4960 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 4960 R-CFA-9696179 https://reactome.org/PathwayBrowser/#/R-CFA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Canis familiaris 4960 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 4960 R-GGA-9696179 https://reactome.org/PathwayBrowser/#/R-GGA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Gallus gallus 4960 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 4960 R-HSA-9696179 https://reactome.org/PathwayBrowser/#/R-HSA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs TAS Homo sapiens 4960 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 4960 R-MMU-9696179 https://reactome.org/PathwayBrowser/#/R-MMU-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Mus musculus 4960 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 4960 R-RNO-9696179 https://reactome.org/PathwayBrowser/#/R-RNO-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Rattus norvegicus 4960 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 4960 R-SSC-9696179 https://reactome.org/PathwayBrowser/#/R-SSC-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Sus scrofa 4960 R-XTR-9696179 https://reactome.org/PathwayBrowser/#/R-XTR-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Xenopus tropicalis 50 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 50 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 50 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 50 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 50 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 50 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 50 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 50 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 50 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 50 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 50 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 50 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 50 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 50 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 50 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 50 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 50 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 50 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 50 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 50 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 50 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 50 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 50 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 50 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 50 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 50 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 50 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 50 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 5003 R-BTA-9724670 https://reactome.org/PathwayBrowser/#/R-BTA-9724670 C-ter TLR7 dimer binds imiquimod IEA Bos taurus 5003 R-CFA-9724670 https://reactome.org/PathwayBrowser/#/R-CFA-9724670 C-ter TLR7 dimer binds imiquimod IEA Canis familiaris 5003 R-GGA-1008270 https://reactome.org/PathwayBrowser/#/R-GGA-1008270 Activated TAK1 leaves endosome membrane IEA Gallus gallus 5003 R-GGA-451439 https://reactome.org/PathwayBrowser/#/R-GGA-451439 Activated TLR7 or 21 recruits MyD88 IEA Gallus gallus 5003 R-GGA-451461 https://reactome.org/PathwayBrowser/#/R-GGA-451461 IRAK4 binds to the activated TLR7 or 21 IEA Gallus gallus 5003 R-GGA-451481 https://reactome.org/PathwayBrowser/#/R-GGA-451481 TLR7 binds to recognized ligands TAS Gallus gallus 5003 R-GGA-532630 https://reactome.org/PathwayBrowser/#/R-GGA-532630 p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 IEA Gallus gallus 5003 R-GGA-532632 https://reactome.org/PathwayBrowser/#/R-GGA-532632 TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 IEA Gallus gallus 5003 R-GGA-571316 https://reactome.org/PathwayBrowser/#/R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. IEA Gallus gallus 5003 R-GGA-571318 https://reactome.org/PathwayBrowser/#/R-GGA-571318 Autoubiquitination of oligoTRAF6 bound to p-IRAK2 IEA Gallus gallus 5003 R-GGA-571324 https://reactome.org/PathwayBrowser/#/R-GGA-571324 IRAK2 binds to p-IRAK4:MyD88:activated TLR7 or 21 complex IEA Gallus gallus 5003 R-GGA-571327 https://reactome.org/PathwayBrowser/#/R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex IEA Gallus gallus 5003 R-GGA-573294 https://reactome.org/PathwayBrowser/#/R-GGA-573294 Activated TRAF6 synthesizes free K63 linked pUb chains IEA Gallus gallus 5003 R-GGA-573296 https://reactome.org/PathwayBrowser/#/R-GGA-573296 Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation IEA Gallus gallus 5003 R-GGA-9724670 https://reactome.org/PathwayBrowser/#/R-GGA-9724670 C-ter TLR7 dimer binds imiquimod IEA Gallus gallus 5003 R-GGA-994000 https://reactome.org/PathwayBrowser/#/R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation IEA Gallus gallus 5003 R-HSA-167983 https://reactome.org/PathwayBrowser/#/R-HSA-167983 C-ter TLR7 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 5003 R-HSA-9691204 https://reactome.org/PathwayBrowser/#/R-HSA-9691204 TLR8 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 5003 R-HSA-9724670 https://reactome.org/PathwayBrowser/#/R-HSA-9724670 C-ter TLR7 dimer binds imiquimod TAS Homo sapiens 5003 R-HSA-975098 https://reactome.org/PathwayBrowser/#/R-HSA-975098 MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 TAS Homo sapiens 5003 R-HSA-975100 https://reactome.org/PathwayBrowser/#/R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex TAS Homo sapiens 5003 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 5003 R-HSA-975111 https://reactome.org/PathwayBrowser/#/R-HSA-975111 TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 5003 R-HSA-975115 https://reactome.org/PathwayBrowser/#/R-HSA-975115 IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 5003 R-HSA-975118 https://reactome.org/PathwayBrowser/#/R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex TAS Homo sapiens 5003 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 5003 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 5003 R-HSA-975156 https://reactome.org/PathwayBrowser/#/R-HSA-975156 IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex TAS Homo sapiens 5003 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 5003 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 5003 R-HSA-975175 https://reactome.org/PathwayBrowser/#/R-HSA-975175 MyD88 interacts with the activated TLR receptor 7, 8 or 9 TAS Homo sapiens 5003 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 5003 R-HSA-975188 https://reactome.org/PathwayBrowser/#/R-HSA-975188 TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 5003 R-MMU-9724670 https://reactome.org/PathwayBrowser/#/R-MMU-9724670 C-ter TLR7 dimer binds imiquimod IEA Mus musculus 5003 R-RNO-9724670 https://reactome.org/PathwayBrowser/#/R-RNO-9724670 C-ter TLR7 dimer binds imiquimod IEA Rattus norvegicus 5003 R-SSC-9724670 https://reactome.org/PathwayBrowser/#/R-SSC-9724670 C-ter TLR7 dimer binds imiquimod IEA Sus scrofa 5003 R-XTR-9724670 https://reactome.org/PathwayBrowser/#/R-XTR-9724670 C-ter TLR7 dimer binds imiquimod IEA Xenopus tropicalis 5004 R-BTA-9714924 https://reactome.org/PathwayBrowser/#/R-BTA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Bos taurus 5004 R-BTA-9714959 https://reactome.org/PathwayBrowser/#/R-BTA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Bos taurus 5004 R-CFA-9714924 https://reactome.org/PathwayBrowser/#/R-CFA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Canis familiaris 5004 R-CFA-9714959 https://reactome.org/PathwayBrowser/#/R-CFA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Canis familiaris 5004 R-DRE-9714924 https://reactome.org/PathwayBrowser/#/R-DRE-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Danio rerio 5004 R-DRE-9714959 https://reactome.org/PathwayBrowser/#/R-DRE-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Danio rerio 5004 R-HSA-9714924 https://reactome.org/PathwayBrowser/#/R-HSA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer TAS Homo sapiens 5004 R-HSA-9714959 https://reactome.org/PathwayBrowser/#/R-HSA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer TAS Homo sapiens 5004 R-MMU-9714924 https://reactome.org/PathwayBrowser/#/R-MMU-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Mus musculus 5004 R-MMU-9714959 https://reactome.org/PathwayBrowser/#/R-MMU-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Mus musculus 5004 R-RNO-9714924 https://reactome.org/PathwayBrowser/#/R-RNO-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Rattus norvegicus 5004 R-RNO-9714959 https://reactome.org/PathwayBrowser/#/R-RNO-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Rattus norvegicus 5004 R-SSC-9714924 https://reactome.org/PathwayBrowser/#/R-SSC-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Sus scrofa 5004 R-SSC-9714959 https://reactome.org/PathwayBrowser/#/R-SSC-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Sus scrofa 5004 R-XTR-9714924 https://reactome.org/PathwayBrowser/#/R-XTR-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Xenopus tropicalis 5004 R-XTR-9714959 https://reactome.org/PathwayBrowser/#/R-XTR-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Xenopus tropicalis 5024 R-BTA-168405 https://reactome.org/PathwayBrowser/#/R-BTA-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Bos taurus 5024 R-BTA-168412 https://reactome.org/PathwayBrowser/#/R-BTA-168412 MDP elicits a NOD2 response IEA Bos taurus 5024 R-BTA-450337 https://reactome.org/PathwayBrowser/#/R-BTA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Bos taurus 5024 R-BTA-450346 https://reactome.org/PathwayBrowser/#/R-BTA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Bos taurus 5024 R-BTA-622415 https://reactome.org/PathwayBrowser/#/R-BTA-622415 RIP2 binds NEMO IEA Bos taurus 5024 R-BTA-688136 https://reactome.org/PathwayBrowser/#/R-BTA-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Bos taurus 5024 R-BTA-688137 https://reactome.org/PathwayBrowser/#/R-BTA-688137 RIP2 is K63 polyubiquitinated IEA Bos taurus 5024 R-BTA-688985 https://reactome.org/PathwayBrowser/#/R-BTA-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Bos taurus 5024 R-BTA-706479 https://reactome.org/PathwayBrowser/#/R-BTA-706479 TAK1 is activated IEA Bos taurus 5024 R-BTA-708349 https://reactome.org/PathwayBrowser/#/R-BTA-708349 Activated NOD2 oligomerizes IEA Bos taurus 5024 R-BTA-741411 https://reactome.org/PathwayBrowser/#/R-BTA-741411 CYLD deubiquitinates NEMO IEA Bos taurus 5024 R-BTA-844438 https://reactome.org/PathwayBrowser/#/R-BTA-844438 NLRP1 oligomerizes IEA Bos taurus 5024 R-BTA-844447 https://reactome.org/PathwayBrowser/#/R-BTA-844447 NLRP1 senses MDP IEA Bos taurus 5024 R-BTA-879222 https://reactome.org/PathwayBrowser/#/R-BTA-879222 MDP:NLRP1 binds ATP IEA Bos taurus 5024 R-CFA-168405 https://reactome.org/PathwayBrowser/#/R-CFA-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Canis familiaris 5024 R-CFA-168412 https://reactome.org/PathwayBrowser/#/R-CFA-168412 MDP elicits a NOD2 response IEA Canis familiaris 5024 R-CFA-450337 https://reactome.org/PathwayBrowser/#/R-CFA-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Canis familiaris 5024 R-CFA-450346 https://reactome.org/PathwayBrowser/#/R-CFA-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Canis familiaris 5024 R-CFA-622415 https://reactome.org/PathwayBrowser/#/R-CFA-622415 RIP2 binds NEMO IEA Canis familiaris 5024 R-CFA-688136 https://reactome.org/PathwayBrowser/#/R-CFA-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Canis familiaris 5024 R-CFA-688137 https://reactome.org/PathwayBrowser/#/R-CFA-688137 RIP2 is K63 polyubiquitinated IEA Canis familiaris 5024 R-CFA-688985 https://reactome.org/PathwayBrowser/#/R-CFA-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Canis familiaris 5024 R-CFA-706479 https://reactome.org/PathwayBrowser/#/R-CFA-706479 TAK1 is activated IEA Canis familiaris 5024 R-CFA-708349 https://reactome.org/PathwayBrowser/#/R-CFA-708349 Activated NOD2 oligomerizes IEA Canis familiaris 5024 R-CFA-741386 https://reactome.org/PathwayBrowser/#/R-CFA-741386 RIP2 induces K63-linked ubiquitination of NEMO IEA Canis familiaris 5024 R-CFA-741411 https://reactome.org/PathwayBrowser/#/R-CFA-741411 CYLD deubiquitinates NEMO IEA Canis familiaris 5024 R-CFA-844438 https://reactome.org/PathwayBrowser/#/R-CFA-844438 NLRP1 oligomerizes IEA Canis familiaris 5024 R-CFA-844447 https://reactome.org/PathwayBrowser/#/R-CFA-844447 NLRP1 senses MDP IEA Canis familiaris 5024 R-CFA-879222 https://reactome.org/PathwayBrowser/#/R-CFA-879222 MDP:NLRP1 binds ATP IEA Canis familiaris 5024 R-DDI-168412 https://reactome.org/PathwayBrowser/#/R-DDI-168412 MDP elicits a NOD2 response IEA Dictyostelium discoideum 5024 R-DDI-708349 https://reactome.org/PathwayBrowser/#/R-DDI-708349 Activated NOD2 oligomerizes IEA Dictyostelium discoideum 5024 R-DRE-168405 https://reactome.org/PathwayBrowser/#/R-DRE-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Danio rerio 5024 R-DRE-168412 https://reactome.org/PathwayBrowser/#/R-DRE-168412 MDP elicits a NOD2 response IEA Danio rerio 5024 R-DRE-622415 https://reactome.org/PathwayBrowser/#/R-DRE-622415 RIP2 binds NEMO IEA Danio rerio 5024 R-DRE-688137 https://reactome.org/PathwayBrowser/#/R-DRE-688137 RIP2 is K63 polyubiquitinated IEA Danio rerio 5024 R-DRE-708349 https://reactome.org/PathwayBrowser/#/R-DRE-708349 Activated NOD2 oligomerizes IEA Danio rerio 5024 R-DRE-741386 https://reactome.org/PathwayBrowser/#/R-DRE-741386 RIP2 induces K63-linked ubiquitination of NEMO IEA Danio rerio 5024 R-DRE-741411 https://reactome.org/PathwayBrowser/#/R-DRE-741411 CYLD deubiquitinates NEMO IEA Danio rerio 5024 R-DRE-844438 https://reactome.org/PathwayBrowser/#/R-DRE-844438 NLRP1 oligomerizes IEA Danio rerio 5024 R-DRE-844447 https://reactome.org/PathwayBrowser/#/R-DRE-844447 NLRP1 senses MDP IEA Danio rerio 5024 R-DRE-879222 https://reactome.org/PathwayBrowser/#/R-DRE-879222 MDP:NLRP1 binds ATP IEA Danio rerio 5024 R-GGA-844438 https://reactome.org/PathwayBrowser/#/R-GGA-844438 NLRP1 oligomerizes IEA Gallus gallus 5024 R-GGA-844447 https://reactome.org/PathwayBrowser/#/R-GGA-844447 NLRP1 senses MDP IEA Gallus gallus 5024 R-GGA-879222 https://reactome.org/PathwayBrowser/#/R-GGA-879222 MDP:NLRP1 binds ATP IEA Gallus gallus 5024 R-HSA-168184 https://reactome.org/PathwayBrowser/#/R-HSA-168184 Activated TAK1 mediates phosphorylation of the IKK Complex TAS Homo sapiens 5024 R-HSA-168405 https://reactome.org/PathwayBrowser/#/R-HSA-168405 Activated NOD oligomer recruites RIP2 (RICK) TAS Homo sapiens 5024 R-HSA-168412 https://reactome.org/PathwayBrowser/#/R-HSA-168412 MDP elicits a NOD2 response TAS Homo sapiens 5024 R-HSA-450337 https://reactome.org/PathwayBrowser/#/R-HSA-450337 Activated TAK1 phosphorylates MKK4/MKK7 TAS Homo sapiens 5024 R-HSA-450346 https://reactome.org/PathwayBrowser/#/R-HSA-450346 activated human TAK1 phosphorylates MKK3/MKK6 TAS Homo sapiens 5024 R-HSA-622415 https://reactome.org/PathwayBrowser/#/R-HSA-622415 RIP2 binds NEMO TAS Homo sapiens 5024 R-HSA-688136 https://reactome.org/PathwayBrowser/#/R-HSA-688136 TNFAIP3 (A20) deubiquitinates RIP2 TAS Homo sapiens 5024 R-HSA-688137 https://reactome.org/PathwayBrowser/#/R-HSA-688137 RIP2 is K63 polyubiquitinated TAS Homo sapiens 5024 R-HSA-688985 https://reactome.org/PathwayBrowser/#/R-HSA-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex TAS Homo sapiens 5024 R-HSA-706479 https://reactome.org/PathwayBrowser/#/R-HSA-706479 TAK1 is activated TAS Homo sapiens 5024 R-HSA-708349 https://reactome.org/PathwayBrowser/#/R-HSA-708349 Activated NOD2 oligomerizes TAS Homo sapiens 5024 R-HSA-741386 https://reactome.org/PathwayBrowser/#/R-HSA-741386 RIP2 induces K63-linked ubiquitination of NEMO TAS Homo sapiens 5024 R-HSA-741395 https://reactome.org/PathwayBrowser/#/R-HSA-741395 CARD9 binds RIP2 (and NOD2) IEA Homo sapiens 5024 R-HSA-741411 https://reactome.org/PathwayBrowser/#/R-HSA-741411 CYLD deubiquitinates NEMO TAS Homo sapiens 5024 R-HSA-844438 https://reactome.org/PathwayBrowser/#/R-HSA-844438 NLRP1 oligomerizes TAS Homo sapiens 5024 R-HSA-844447 https://reactome.org/PathwayBrowser/#/R-HSA-844447 NLRP1 senses MDP TAS Homo sapiens 5024 R-HSA-879222 https://reactome.org/PathwayBrowser/#/R-HSA-879222 MDP:NLRP1 binds ATP TAS Homo sapiens 5024 R-MMU-168405 https://reactome.org/PathwayBrowser/#/R-MMU-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Mus musculus 5024 R-MMU-168412 https://reactome.org/PathwayBrowser/#/R-MMU-168412 MDP elicits a NOD2 response IEA Mus musculus 5024 R-MMU-450337 https://reactome.org/PathwayBrowser/#/R-MMU-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Mus musculus 5024 R-MMU-450346 https://reactome.org/PathwayBrowser/#/R-MMU-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Mus musculus 5024 R-MMU-622415 https://reactome.org/PathwayBrowser/#/R-MMU-622415 RIP2 binds NEMO IEA Mus musculus 5024 R-MMU-688136 https://reactome.org/PathwayBrowser/#/R-MMU-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Mus musculus 5024 R-MMU-688137 https://reactome.org/PathwayBrowser/#/R-MMU-688137 RIP2 is K63 polyubiquitinated IEA Mus musculus 5024 R-MMU-688985 https://reactome.org/PathwayBrowser/#/R-MMU-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Mus musculus 5024 R-MMU-706479 https://reactome.org/PathwayBrowser/#/R-MMU-706479 TAK1 is activated IEA Mus musculus 5024 R-MMU-708349 https://reactome.org/PathwayBrowser/#/R-MMU-708349 Activated NOD2 oligomerizes IEA Mus musculus 5024 R-MMU-741383 https://reactome.org/PathwayBrowser/#/R-MMU-741383 Card9 binds Rip2 (and Nod2) TAS Mus musculus 5024 R-MMU-741386 https://reactome.org/PathwayBrowser/#/R-MMU-741386 RIP2 induces K63-linked ubiquitination of NEMO IEA Mus musculus 5024 R-MMU-741411 https://reactome.org/PathwayBrowser/#/R-MMU-741411 CYLD deubiquitinates NEMO IEA Mus musculus 5024 R-MMU-844438 https://reactome.org/PathwayBrowser/#/R-MMU-844438 NLRP1 oligomerizes IEA Mus musculus 5024 R-MMU-844447 https://reactome.org/PathwayBrowser/#/R-MMU-844447 NLRP1 senses MDP IEA Mus musculus 5024 R-MMU-879222 https://reactome.org/PathwayBrowser/#/R-MMU-879222 MDP:NLRP1 binds ATP IEA Mus musculus 5024 R-RNO-168405 https://reactome.org/PathwayBrowser/#/R-RNO-168405 Activated NOD oligomer recruites RIP2 (RICK) IEA Rattus norvegicus 5024 R-RNO-168412 https://reactome.org/PathwayBrowser/#/R-RNO-168412 MDP elicits a NOD2 response IEA Rattus norvegicus 5024 R-RNO-450337 https://reactome.org/PathwayBrowser/#/R-RNO-450337 Activated TAK1 phosphorylates MKK4/MKK7 IEA Rattus norvegicus 5024 R-RNO-450346 https://reactome.org/PathwayBrowser/#/R-RNO-450346 activated human TAK1 phosphorylates MKK3/MKK6 IEA Rattus norvegicus 5024 R-RNO-622415 https://reactome.org/PathwayBrowser/#/R-RNO-622415 RIP2 binds NEMO IEA Rattus norvegicus 5024 R-RNO-688136 https://reactome.org/PathwayBrowser/#/R-RNO-688136 TNFAIP3 (A20) deubiquitinates RIP2 IEA Rattus norvegicus 5024 R-RNO-688137 https://reactome.org/PathwayBrowser/#/R-RNO-688137 RIP2 is K63 polyubiquitinated IEA Rattus norvegicus 5024 R-RNO-688985 https://reactome.org/PathwayBrowser/#/R-RNO-688985 K63 polyubiquitinated RIP2 associates with the TAK1 complex IEA Rattus norvegicus 5024 R-RNO-706479 https://reactome.org/PathwayBrowser/#/R-RNO-706479 TAK1 is activated IEA Rattus norvegicus 5024 R-RNO-708349 https://reactome.org/PathwayBrowser/#/R-RNO-708349 Activated NOD2 oligomerizes IEA Rattus norvegicus 5024 R-RNO-741411 https://reactome.org/PathwayBrowser/#/R-RNO-741411 CYLD deubiquitinates NEMO IEA Rattus norvegicus 5024 R-RNO-844438 https://reactome.org/PathwayBrowser/#/R-RNO-844438 NLRP1 oligomerizes IEA Rattus norvegicus 5024 R-RNO-844447 https://reactome.org/PathwayBrowser/#/R-RNO-844447 NLRP1 senses MDP IEA Rattus norvegicus 5024 R-RNO-879222 https://reactome.org/PathwayBrowser/#/R-RNO-879222 MDP:NLRP1 binds ATP IEA Rattus norvegicus 503 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 503 R-BTA-9617370 https://reactome.org/PathwayBrowser/#/R-BTA-9617370 α1-antagonists bind ADRA1A,B,D IEA Bos taurus 503 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 503 R-CEL-9617370 https://reactome.org/PathwayBrowser/#/R-CEL-9617370 α1-antagonists bind ADRA1A,B,D IEA Caenorhabditis elegans 503 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 503 R-CFA-9617370 https://reactome.org/PathwayBrowser/#/R-CFA-9617370 α1-antagonists bind ADRA1A,B,D IEA Canis familiaris 503 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 503 R-DME-9617370 https://reactome.org/PathwayBrowser/#/R-DME-9617370 α1-antagonists bind ADRA1A,B,D IEA Drosophila melanogaster 503 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 503 R-DRE-9617370 https://reactome.org/PathwayBrowser/#/R-DRE-9617370 α1-antagonists bind ADRA1A,B,D IEA Danio rerio 503 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 503 R-GGA-9617370 https://reactome.org/PathwayBrowser/#/R-GGA-9617370 α1-antagonists bind ADRA1A,B,D IEA Gallus gallus 503 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 503 R-HSA-9617370 https://reactome.org/PathwayBrowser/#/R-HSA-9617370 α1-antagonists bind ADRA1A,B,D TAS Homo sapiens 503 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 503 R-MMU-9617370 https://reactome.org/PathwayBrowser/#/R-MMU-9617370 α1-antagonists bind ADRA1A,B,D IEA Mus musculus 503 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 503 R-RNO-9617370 https://reactome.org/PathwayBrowser/#/R-RNO-9617370 α1-antagonists bind ADRA1A,B,D IEA Rattus norvegicus 503 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 503 R-SSC-9617370 https://reactome.org/PathwayBrowser/#/R-SSC-9617370 α1-antagonists bind ADRA1A,B,D IEA Sus scrofa 503 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 503 R-XTR-9617370 https://reactome.org/PathwayBrowser/#/R-XTR-9617370 α1-antagonists bind ADRA1A,B,D IEA Xenopus tropicalis 5037 R-HSA-1839039 https://reactome.org/PathwayBrowser/#/R-HSA-1839039 Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation TAS Homo sapiens 5037 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 5037 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 5037 R-HSA-2046363 https://reactome.org/PathwayBrowser/#/R-HSA-2046363 FGFR4 kinase mutants are inhibited by PD170734 TAS Homo sapiens 5037 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 5037 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 5046 R-CFA-1963589 https://reactome.org/PathwayBrowser/#/R-CFA-1963589 ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 IEA Canis familiaris 5046 R-HSA-1963589 https://reactome.org/PathwayBrowser/#/R-HSA-1963589 ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 TAS Homo sapiens 5046 R-HSA-9665703 https://reactome.org/PathwayBrowser/#/R-HSA-9665703 ERBB2 TMD/JMD mutants bind pertuzumab TAS Homo sapiens 5046 R-HSA-9665708 https://reactome.org/PathwayBrowser/#/R-HSA-9665708 ERBB2 TMD/JMD mutants do not bind pertuzumab TAS Homo sapiens 5046 R-HSA-9665726 https://reactome.org/PathwayBrowser/#/R-HSA-9665726 ERBB2 binds pertuzumab TAS Homo sapiens 5046 R-MMU-1963589 https://reactome.org/PathwayBrowser/#/R-MMU-1963589 ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 IEA Mus musculus 5051 R-GGA-1008270 https://reactome.org/PathwayBrowser/#/R-GGA-1008270 Activated TAK1 leaves endosome membrane IEA Gallus gallus 5051 R-GGA-451439 https://reactome.org/PathwayBrowser/#/R-GGA-451439 Activated TLR7 or 21 recruits MyD88 IEA Gallus gallus 5051 R-GGA-451461 https://reactome.org/PathwayBrowser/#/R-GGA-451461 IRAK4 binds to the activated TLR7 or 21 IEA Gallus gallus 5051 R-GGA-451481 https://reactome.org/PathwayBrowser/#/R-GGA-451481 TLR7 binds to recognized ligands TAS Gallus gallus 5051 R-GGA-532630 https://reactome.org/PathwayBrowser/#/R-GGA-532630 p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 IEA Gallus gallus 5051 R-GGA-532632 https://reactome.org/PathwayBrowser/#/R-GGA-532632 TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 IEA Gallus gallus 5051 R-GGA-571316 https://reactome.org/PathwayBrowser/#/R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. IEA Gallus gallus 5051 R-GGA-571318 https://reactome.org/PathwayBrowser/#/R-GGA-571318 Autoubiquitination of oligoTRAF6 bound to p-IRAK2 IEA Gallus gallus 5051 R-GGA-571324 https://reactome.org/PathwayBrowser/#/R-GGA-571324 IRAK2 binds to p-IRAK4:MyD88:activated TLR7 or 21 complex IEA Gallus gallus 5051 R-GGA-571327 https://reactome.org/PathwayBrowser/#/R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex IEA Gallus gallus 5051 R-GGA-573294 https://reactome.org/PathwayBrowser/#/R-GGA-573294 Activated TRAF6 synthesizes free K63 linked pUb chains IEA Gallus gallus 5051 R-GGA-573296 https://reactome.org/PathwayBrowser/#/R-GGA-573296 Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation IEA Gallus gallus 5051 R-GGA-994000 https://reactome.org/PathwayBrowser/#/R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation IEA Gallus gallus 5051 R-HSA-167983 https://reactome.org/PathwayBrowser/#/R-HSA-167983 C-ter TLR7 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 5051 R-HSA-9691204 https://reactome.org/PathwayBrowser/#/R-HSA-9691204 TLR8 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 5051 R-HSA-975098 https://reactome.org/PathwayBrowser/#/R-HSA-975098 MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 TAS Homo sapiens 5051 R-HSA-975100 https://reactome.org/PathwayBrowser/#/R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex TAS Homo sapiens 5051 R-HSA-975106 https://reactome.org/PathwayBrowser/#/R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 5051 R-HSA-975111 https://reactome.org/PathwayBrowser/#/R-HSA-975111 TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 5051 R-HSA-975115 https://reactome.org/PathwayBrowser/#/R-HSA-975115 IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 5051 R-HSA-975118 https://reactome.org/PathwayBrowser/#/R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex TAS Homo sapiens 5051 R-HSA-975125 https://reactome.org/PathwayBrowser/#/R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 TAS Homo sapiens 5051 R-HSA-975134 https://reactome.org/PathwayBrowser/#/R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 TAS Homo sapiens 5051 R-HSA-975156 https://reactome.org/PathwayBrowser/#/R-HSA-975156 IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex TAS Homo sapiens 5051 R-HSA-975160 https://reactome.org/PathwayBrowser/#/R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 TAS Homo sapiens 5051 R-HSA-975170 https://reactome.org/PathwayBrowser/#/R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 5051 R-HSA-975175 https://reactome.org/PathwayBrowser/#/R-HSA-975175 MyD88 interacts with the activated TLR receptor 7, 8 or 9 TAS Homo sapiens 5051 R-HSA-975180 https://reactome.org/PathwayBrowser/#/R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 TAS Homo sapiens 5051 R-HSA-975188 https://reactome.org/PathwayBrowser/#/R-HSA-975188 TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation TAS Homo sapiens 5056 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5056 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5056 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5056 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 5056 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 5056 R-HSA-9702578 https://reactome.org/PathwayBrowser/#/R-HSA-9702578 semaxanib-resistant FLT3 mutants don't bind semaxanib
TAS Homo sapiens 5056 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5056 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5057 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 5057 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 5057 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 5057 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 5057 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 5057 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 5057 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 5057 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 5057 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 5057 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 5057 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 5057 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 5057 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 5057 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 5057 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 5057 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 5057 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 5057 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 5082 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 5082 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 5082 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 5082 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 5082 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 5082 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 5082 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 5082 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 5082 R-HSA-9649393 https://reactome.org/PathwayBrowser/#/R-HSA-9649393 ERBB2 KD mutants bind trastuzumab TAS Homo sapiens 5082 R-HSA-9652277 https://reactome.org/PathwayBrowser/#/R-HSA-9652277 ERBB2 binds trastuzumab TAS Homo sapiens 5082 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 5082 R-HSA-9665232 https://reactome.org/PathwayBrowser/#/R-HSA-9665232 Resistant ERBB2 KD mutants do not bind trastuzumab TAS Homo sapiens 5082 R-HSA-9665389 https://reactome.org/PathwayBrowser/#/R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate TAS Homo sapiens 5082 R-HSA-9665405 https://reactome.org/PathwayBrowser/#/R-HSA-9665405 ERBB2 ECD mutants bind trastuzumab TAS Homo sapiens 5082 R-HSA-9665696 https://reactome.org/PathwayBrowser/#/R-HSA-9665696 ERBB2 TMD/JMD mutants bind trastuzumab TAS Homo sapiens 5082 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 5082 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 5082 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 5099 R-BTA-1855180 https://reactome.org/PathwayBrowser/#/R-BTA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Bos taurus 5099 R-CEL-1855180 https://reactome.org/PathwayBrowser/#/R-CEL-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Caenorhabditis elegans 5099 R-CFA-1855180 https://reactome.org/PathwayBrowser/#/R-CFA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Canis familiaris 5099 R-DME-1855180 https://reactome.org/PathwayBrowser/#/R-DME-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Drosophila melanogaster 5099 R-DRE-1855180 https://reactome.org/PathwayBrowser/#/R-DRE-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Danio rerio 5099 R-GGA-1855180 https://reactome.org/PathwayBrowser/#/R-GGA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Gallus gallus 5099 R-HSA-1855180 https://reactome.org/PathwayBrowser/#/R-HSA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol TAS Homo sapiens 5099 R-HSA-6809561 https://reactome.org/PathwayBrowser/#/R-HSA-6809561 I(1,3)P2 is dephosphorylated into I1P by MTMR7 IEA Homo sapiens 5099 R-HSA-6809565 https://reactome.org/PathwayBrowser/#/R-HSA-6809565 I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 IEA Homo sapiens 5099 R-MMU-1855180 https://reactome.org/PathwayBrowser/#/R-MMU-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Mus musculus 5099 R-MMU-6809624 https://reactome.org/PathwayBrowser/#/R-MMU-6809624 I(1,3)P2 is dephosphorylated into I1P by Mtmr7 TAS Mus musculus 5099 R-MMU-6809627 https://reactome.org/PathwayBrowser/#/R-MMU-6809627 I(1,3)P2 is dephosphorylated into I1P by Mtmr7:Mtmr9 TAS Mus musculus 5099 R-RNO-1855180 https://reactome.org/PathwayBrowser/#/R-RNO-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Rattus norvegicus 5099 R-SSC-1855180 https://reactome.org/PathwayBrowser/#/R-SSC-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Sus scrofa 5099 R-XTR-1855180 https://reactome.org/PathwayBrowser/#/R-XTR-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Xenopus tropicalis 51 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 51 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 51 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 51 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 51 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 51 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 51 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 51 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 51 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 51 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 5100 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 5100 R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 5100 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 5100 R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 5100 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 5100 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 5100 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 5100 R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 5100 R-HSA-194025 https://reactome.org/PathwayBrowser/#/R-HSA-194025 11-deoxycortisol translocates to the mitochondrion TAS Homo sapiens 5100 R-HSA-5580292 https://reactome.org/PathwayBrowser/#/R-HSA-5580292 Defective CYP11B1 does not oxidise 11DCORT TAS Homo sapiens 5100 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 5100 R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 5100 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 5100 R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 5100 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 5100 R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 5100 R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 5103 R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 5103 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 5103 R-BTA-196372 https://reactome.org/PathwayBrowser/#/R-BTA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Bos taurus 5103 R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 5103 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 5103 R-CFA-196372 https://reactome.org/PathwayBrowser/#/R-CFA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Canis familiaris 5103 R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 5103 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 5103 R-DRE-196372 https://reactome.org/PathwayBrowser/#/R-DRE-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Danio rerio 5103 R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 5103 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 5103 R-GGA-196372 https://reactome.org/PathwayBrowser/#/R-GGA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Gallus gallus 5103 R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 5103 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 5103 R-HSA-196372 https://reactome.org/PathwayBrowser/#/R-HSA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol TAS Homo sapiens 5103 R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 5103 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 5103 R-MMU-196372 https://reactome.org/PathwayBrowser/#/R-MMU-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Mus musculus 5103 R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 5103 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 5103 R-RNO-196372 https://reactome.org/PathwayBrowser/#/R-RNO-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Rattus norvegicus 5103 R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 5103 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 5103 R-SSC-196372 https://reactome.org/PathwayBrowser/#/R-SSC-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Sus scrofa 5103 R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 5103 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 5104 R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 5104 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 5104 R-BTA-193961 https://reactome.org/PathwayBrowser/#/R-BTA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Bos taurus 5104 R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 5104 R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 5104 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 5104 R-CFA-193961 https://reactome.org/PathwayBrowser/#/R-CFA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Canis familiaris 5104 R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 5104 R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 5104 R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 5104 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 5104 R-DRE-193961 https://reactome.org/PathwayBrowser/#/R-DRE-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Danio rerio 5104 R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 5104 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 5104 R-GGA-193961 https://reactome.org/PathwayBrowser/#/R-GGA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Gallus gallus 5104 R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 5104 R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 5104 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 5104 R-HSA-193961 https://reactome.org/PathwayBrowser/#/R-HSA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone TAS Homo sapiens 5104 R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 5104 R-HSA-9035956 https://reactome.org/PathwayBrowser/#/R-HSA-9035956 Defective CYP17A1 does not cleave 17aHPROG TAS Homo sapiens 5104 R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 5104 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 5104 R-MMU-193961 https://reactome.org/PathwayBrowser/#/R-MMU-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Mus musculus 5104 R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 5104 R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 5104 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 5104 R-RNO-193961 https://reactome.org/PathwayBrowser/#/R-RNO-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Rattus norvegicus 5104 R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 5104 R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 5104 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 5104 R-SSC-193961 https://reactome.org/PathwayBrowser/#/R-SSC-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone IEA Sus scrofa 5104 R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 5104 R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 5104 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 5109 R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 5109 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 5109 R-BTA-109530 https://reactome.org/PathwayBrowser/#/R-BTA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Bos taurus 5109 R-BTA-109624 https://reactome.org/PathwayBrowser/#/R-BTA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Bos taurus 5109 R-BTA-109671 https://reactome.org/PathwayBrowser/#/R-BTA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Bos taurus 5109 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 5109 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 5109 R-CEL-109530 https://reactome.org/PathwayBrowser/#/R-CEL-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Caenorhabditis elegans 5109 R-CEL-109624 https://reactome.org/PathwayBrowser/#/R-CEL-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Caenorhabditis elegans 5109 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 5109 R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 5109 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 5109 R-CFA-109624 https://reactome.org/PathwayBrowser/#/R-CFA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Canis familiaris 5109 R-CFA-109671 https://reactome.org/PathwayBrowser/#/R-CFA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Canis familiaris 5109 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 5109 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 5109 R-DDI-109624 https://reactome.org/PathwayBrowser/#/R-DDI-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Dictyostelium discoideum 5109 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 5109 R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 5109 R-DME-109530 https://reactome.org/PathwayBrowser/#/R-DME-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Drosophila melanogaster 5109 R-DME-109624 https://reactome.org/PathwayBrowser/#/R-DME-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Drosophila melanogaster 5109 R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 5109 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 5109 R-DRE-109624 https://reactome.org/PathwayBrowser/#/R-DRE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Danio rerio 5109 R-DRE-109671 https://reactome.org/PathwayBrowser/#/R-DRE-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Danio rerio 5109 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 5109 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 5109 R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 5109 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 5109 R-GGA-109624 https://reactome.org/PathwayBrowser/#/R-GGA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Gallus gallus 5109 R-GGA-109671 https://reactome.org/PathwayBrowser/#/R-GGA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Gallus gallus 5109 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 5109 R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 5109 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 5109 R-HSA-109530 https://reactome.org/PathwayBrowser/#/R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 TAS Homo sapiens 5109 R-HSA-109624 https://reactome.org/PathwayBrowser/#/R-HSA-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) TAS Homo sapiens 5109 R-HSA-109671 https://reactome.org/PathwayBrowser/#/R-HSA-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) TAS Homo sapiens 5109 R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 5109 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 5109 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 5109 R-HSA-9734745 https://reactome.org/PathwayBrowser/#/R-HSA-9734745 Defective ADA does not deaminate (deoxy)adenosine TAS Homo sapiens 5109 R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 5109 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 5109 R-MMU-109530 https://reactome.org/PathwayBrowser/#/R-MMU-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Mus musculus 5109 R-MMU-109624 https://reactome.org/PathwayBrowser/#/R-MMU-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Mus musculus 5109 R-MMU-109671 https://reactome.org/PathwayBrowser/#/R-MMU-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Mus musculus 5109 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 5109 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 5109 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 5109 R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 5109 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 5109 R-RNO-109530 https://reactome.org/PathwayBrowser/#/R-RNO-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Rattus norvegicus 5109 R-RNO-109624 https://reactome.org/PathwayBrowser/#/R-RNO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Rattus norvegicus 5109 R-RNO-109671 https://reactome.org/PathwayBrowser/#/R-RNO-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Rattus norvegicus 5109 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 5109 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 5109 R-SCE-109624 https://reactome.org/PathwayBrowser/#/R-SCE-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Saccharomyces cerevisiae 5109 R-SPO-109624 https://reactome.org/PathwayBrowser/#/R-SPO-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Schizosaccharomyces pombe 5109 R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 5109 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 5109 R-SSC-109530 https://reactome.org/PathwayBrowser/#/R-SSC-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Sus scrofa 5109 R-SSC-109624 https://reactome.org/PathwayBrowser/#/R-SSC-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Sus scrofa 5109 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 5109 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 5109 R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 5109 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 5109 R-XTR-109530 https://reactome.org/PathwayBrowser/#/R-XTR-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 IEA Xenopus tropicalis 5109 R-XTR-109624 https://reactome.org/PathwayBrowser/#/R-XTR-109624 (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) IEA Xenopus tropicalis 5109 R-XTR-109671 https://reactome.org/PathwayBrowser/#/R-XTR-109671 deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) IEA Xenopus tropicalis 5109 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 5109 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 5110 R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 5110 R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 5110 R-BTA-112033 https://reactome.org/PathwayBrowser/#/R-BTA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Bos taurus 5110 R-BTA-74207 https://reactome.org/PathwayBrowser/#/R-BTA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Bos taurus 5110 R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 5110 R-BTA-74242 https://reactome.org/PathwayBrowser/#/R-BTA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Bos taurus 5110 R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 5110 R-CEL-112033 https://reactome.org/PathwayBrowser/#/R-CEL-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Caenorhabditis elegans 5110 R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 5110 R-CEL-74242 https://reactome.org/PathwayBrowser/#/R-CEL-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Caenorhabditis elegans 5110 R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 5110 R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 5110 R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 5110 R-CFA-112033 https://reactome.org/PathwayBrowser/#/R-CFA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Canis familiaris 5110 R-CFA-74207 https://reactome.org/PathwayBrowser/#/R-CFA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Canis familiaris 5110 R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 5110 R-CFA-74242 https://reactome.org/PathwayBrowser/#/R-CFA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Canis familiaris 5110 R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 5110 R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 5110 R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 5110 R-DME-112033 https://reactome.org/PathwayBrowser/#/R-DME-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Drosophila melanogaster 5110 R-DME-74242 https://reactome.org/PathwayBrowser/#/R-DME-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Drosophila melanogaster 5110 R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 5110 R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 5110 R-DRE-112033 https://reactome.org/PathwayBrowser/#/R-DRE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Danio rerio 5110 R-DRE-74207 https://reactome.org/PathwayBrowser/#/R-DRE-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Danio rerio 5110 R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 5110 R-DRE-74242 https://reactome.org/PathwayBrowser/#/R-DRE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Danio rerio 5110 R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 5110 R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 5110 R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 5110 R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 5110 R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 5110 R-HSA-112033 https://reactome.org/PathwayBrowser/#/R-HSA-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine TAS Homo sapiens 5110 R-HSA-74207 https://reactome.org/PathwayBrowser/#/R-HSA-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) TAS Homo sapiens 5110 R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 5110 R-HSA-74242 https://reactome.org/PathwayBrowser/#/R-HSA-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 5110 R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 5110 R-HSA-9735775 https://reactome.org/PathwayBrowser/#/R-HSA-9735775 Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose TAS Homo sapiens 5110 R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 5110 R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 5110 R-MMU-112033 https://reactome.org/PathwayBrowser/#/R-MMU-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Mus musculus 5110 R-MMU-74207 https://reactome.org/PathwayBrowser/#/R-MMU-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Mus musculus 5110 R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 5110 R-MMU-74242 https://reactome.org/PathwayBrowser/#/R-MMU-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Mus musculus 5110 R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 5110 R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 5110 R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 5110 R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 5110 R-RNO-112033 https://reactome.org/PathwayBrowser/#/R-RNO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Rattus norvegicus 5110 R-RNO-74207 https://reactome.org/PathwayBrowser/#/R-RNO-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Rattus norvegicus 5110 R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 5110 R-RNO-74242 https://reactome.org/PathwayBrowser/#/R-RNO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Rattus norvegicus 5110 R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 5110 R-SCE-112033 https://reactome.org/PathwayBrowser/#/R-SCE-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Saccharomyces cerevisiae 5110 R-SCE-74242 https://reactome.org/PathwayBrowser/#/R-SCE-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Saccharomyces cerevisiae 5110 R-SPO-112033 https://reactome.org/PathwayBrowser/#/R-SPO-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Schizosaccharomyces pombe 5110 R-SPO-74242 https://reactome.org/PathwayBrowser/#/R-SPO-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Schizosaccharomyces pombe 5110 R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 5110 R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 5110 R-SSC-112033 https://reactome.org/PathwayBrowser/#/R-SSC-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Sus scrofa 5110 R-SSC-74207 https://reactome.org/PathwayBrowser/#/R-SSC-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Sus scrofa 5110 R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 5110 R-SSC-74242 https://reactome.org/PathwayBrowser/#/R-SSC-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Sus scrofa 5110 R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 5110 R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 5110 R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 5110 R-XTR-112033 https://reactome.org/PathwayBrowser/#/R-XTR-112033 PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine IEA Xenopus tropicalis 5110 R-XTR-74207 https://reactome.org/PathwayBrowser/#/R-XTR-74207 dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) IEA Xenopus tropicalis 5110 R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 5110 R-XTR-74242 https://reactome.org/PathwayBrowser/#/R-XTR-74242 PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose IEA Xenopus tropicalis 5110 R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 5117 R-BTA-209815 https://reactome.org/PathwayBrowser/#/R-BTA-209815 Tyrosine is monoiodinated IEA Bos taurus 5117 R-BTA-209921 https://reactome.org/PathwayBrowser/#/R-BTA-209921 Monoiodinated tyrosine can be deiodinated IEA Bos taurus 5117 R-BTA-209925 https://reactome.org/PathwayBrowser/#/R-BTA-209925 DIT and MIT combine to form triiodothyronine IEA Bos taurus 5117 R-CEL-209815 https://reactome.org/PathwayBrowser/#/R-CEL-209815 Tyrosine is monoiodinated IEA Caenorhabditis elegans 5117 R-CEL-209921 https://reactome.org/PathwayBrowser/#/R-CEL-209921 Monoiodinated tyrosine can be deiodinated IEA Caenorhabditis elegans 5117 R-CEL-209925 https://reactome.org/PathwayBrowser/#/R-CEL-209925 DIT and MIT combine to form triiodothyronine IEA Caenorhabditis elegans 5117 R-CFA-209815 https://reactome.org/PathwayBrowser/#/R-CFA-209815 Tyrosine is monoiodinated IEA Canis familiaris 5117 R-CFA-209921 https://reactome.org/PathwayBrowser/#/R-CFA-209921 Monoiodinated tyrosine can be deiodinated IEA Canis familiaris 5117 R-CFA-209925 https://reactome.org/PathwayBrowser/#/R-CFA-209925 DIT and MIT combine to form triiodothyronine IEA Canis familiaris 5117 R-DME-209815 https://reactome.org/PathwayBrowser/#/R-DME-209815 Tyrosine is monoiodinated IEA Drosophila melanogaster 5117 R-DME-209921 https://reactome.org/PathwayBrowser/#/R-DME-209921 Monoiodinated tyrosine can be deiodinated IEA Drosophila melanogaster 5117 R-DME-209925 https://reactome.org/PathwayBrowser/#/R-DME-209925 DIT and MIT combine to form triiodothyronine IEA Drosophila melanogaster 5117 R-DRE-209921 https://reactome.org/PathwayBrowser/#/R-DRE-209921 Monoiodinated tyrosine can be deiodinated IEA Danio rerio 5117 R-GGA-209815 https://reactome.org/PathwayBrowser/#/R-GGA-209815 Tyrosine is monoiodinated IEA Gallus gallus 5117 R-GGA-209921 https://reactome.org/PathwayBrowser/#/R-GGA-209921 Monoiodinated tyrosine can be deiodinated IEA Gallus gallus 5117 R-GGA-209925 https://reactome.org/PathwayBrowser/#/R-GGA-209925 DIT and MIT combine to form triiodothyronine IEA Gallus gallus 5117 R-HSA-209815 https://reactome.org/PathwayBrowser/#/R-HSA-209815 Tyrosine is monoiodinated TAS Homo sapiens 5117 R-HSA-209921 https://reactome.org/PathwayBrowser/#/R-HSA-209921 Monoiodinated tyrosine can be deiodinated TAS Homo sapiens 5117 R-HSA-209925 https://reactome.org/PathwayBrowser/#/R-HSA-209925 DIT and MIT combine to form triiodothyronine TAS Homo sapiens 5117 R-MMU-209815 https://reactome.org/PathwayBrowser/#/R-MMU-209815 Tyrosine is monoiodinated IEA Mus musculus 5117 R-MMU-209921 https://reactome.org/PathwayBrowser/#/R-MMU-209921 Monoiodinated tyrosine can be deiodinated IEA Mus musculus 5117 R-MMU-209925 https://reactome.org/PathwayBrowser/#/R-MMU-209925 DIT and MIT combine to form triiodothyronine IEA Mus musculus 5117 R-RNO-209815 https://reactome.org/PathwayBrowser/#/R-RNO-209815 Tyrosine is monoiodinated IEA Rattus norvegicus 5117 R-RNO-209921 https://reactome.org/PathwayBrowser/#/R-RNO-209921 Monoiodinated tyrosine can be deiodinated IEA Rattus norvegicus 5117 R-RNO-209925 https://reactome.org/PathwayBrowser/#/R-RNO-209925 DIT and MIT combine to form triiodothyronine IEA Rattus norvegicus 5117 R-SSC-209815 https://reactome.org/PathwayBrowser/#/R-SSC-209815 Tyrosine is monoiodinated IEA Sus scrofa 5117 R-SSC-209921 https://reactome.org/PathwayBrowser/#/R-SSC-209921 Monoiodinated tyrosine can be deiodinated IEA Sus scrofa 5117 R-SSC-209925 https://reactome.org/PathwayBrowser/#/R-SSC-209925 DIT and MIT combine to form triiodothyronine IEA Sus scrofa 5117 R-XTR-209815 https://reactome.org/PathwayBrowser/#/R-XTR-209815 Tyrosine is monoiodinated IEA Xenopus tropicalis 5117 R-XTR-209921 https://reactome.org/PathwayBrowser/#/R-XTR-209921 Monoiodinated tyrosine can be deiodinated IEA Xenopus tropicalis 5117 R-XTR-209925 https://reactome.org/PathwayBrowser/#/R-XTR-209925 DIT and MIT combine to form triiodothyronine IEA Xenopus tropicalis 5121 R-BTA-351210 https://reactome.org/PathwayBrowser/#/R-BTA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Bos taurus 5121 R-BTA-351215 https://reactome.org/PathwayBrowser/#/R-BTA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Bos taurus 5121 R-BTA-351222 https://reactome.org/PathwayBrowser/#/R-BTA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Bos taurus 5121 R-CEL-351215 https://reactome.org/PathwayBrowser/#/R-CEL-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Caenorhabditis elegans 5121 R-CEL-351222 https://reactome.org/PathwayBrowser/#/R-CEL-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Caenorhabditis elegans 5121 R-CFA-351210 https://reactome.org/PathwayBrowser/#/R-CFA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Canis familiaris 5121 R-CFA-351215 https://reactome.org/PathwayBrowser/#/R-CFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Canis familiaris 5121 R-CFA-351222 https://reactome.org/PathwayBrowser/#/R-CFA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Canis familiaris 5121 R-DDI-351215 https://reactome.org/PathwayBrowser/#/R-DDI-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Dictyostelium discoideum 5121 R-DDI-351222 https://reactome.org/PathwayBrowser/#/R-DDI-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Dictyostelium discoideum 5121 R-DME-351210 https://reactome.org/PathwayBrowser/#/R-DME-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Drosophila melanogaster 5121 R-DME-351215 https://reactome.org/PathwayBrowser/#/R-DME-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Drosophila melanogaster 5121 R-DME-351222 https://reactome.org/PathwayBrowser/#/R-DME-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Drosophila melanogaster 5121 R-DRE-351210 https://reactome.org/PathwayBrowser/#/R-DRE-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Danio rerio 5121 R-DRE-351222 https://reactome.org/PathwayBrowser/#/R-DRE-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Danio rerio 5121 R-GGA-351210 https://reactome.org/PathwayBrowser/#/R-GGA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Gallus gallus 5121 R-GGA-351215 https://reactome.org/PathwayBrowser/#/R-GGA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Gallus gallus 5121 R-GGA-351222 https://reactome.org/PathwayBrowser/#/R-GGA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Gallus gallus 5121 R-HSA-351210 https://reactome.org/PathwayBrowser/#/R-HSA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine TAS Homo sapiens 5121 R-HSA-351215 https://reactome.org/PathwayBrowser/#/R-HSA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine TAS Homo sapiens 5121 R-HSA-351222 https://reactome.org/PathwayBrowser/#/R-HSA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 TAS Homo sapiens 5121 R-MMU-351210 https://reactome.org/PathwayBrowser/#/R-MMU-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Mus musculus 5121 R-MMU-351215 https://reactome.org/PathwayBrowser/#/R-MMU-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Mus musculus 5121 R-MMU-351222 https://reactome.org/PathwayBrowser/#/R-MMU-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Mus musculus 5121 R-PFA-351215 https://reactome.org/PathwayBrowser/#/R-PFA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Plasmodium falciparum 5121 R-RNO-351210 https://reactome.org/PathwayBrowser/#/R-RNO-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Rattus norvegicus 5121 R-RNO-351215 https://reactome.org/PathwayBrowser/#/R-RNO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Rattus norvegicus 5121 R-RNO-351222 https://reactome.org/PathwayBrowser/#/R-RNO-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Rattus norvegicus 5121 R-SCE-351215 https://reactome.org/PathwayBrowser/#/R-SCE-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Saccharomyces cerevisiae 5121 R-SCE-351222 https://reactome.org/PathwayBrowser/#/R-SCE-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Saccharomyces cerevisiae 5121 R-SPO-351215 https://reactome.org/PathwayBrowser/#/R-SPO-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Schizosaccharomyces pombe 5121 R-SPO-351222 https://reactome.org/PathwayBrowser/#/R-SPO-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Schizosaccharomyces pombe 5121 R-SSC-351210 https://reactome.org/PathwayBrowser/#/R-SSC-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Sus scrofa 5121 R-SSC-351215 https://reactome.org/PathwayBrowser/#/R-SSC-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Sus scrofa 5121 R-SSC-351222 https://reactome.org/PathwayBrowser/#/R-SSC-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Sus scrofa 5121 R-XTR-351210 https://reactome.org/PathwayBrowser/#/R-XTR-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine IEA Xenopus tropicalis 5121 R-XTR-351215 https://reactome.org/PathwayBrowser/#/R-XTR-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine IEA Xenopus tropicalis 5121 R-XTR-351222 https://reactome.org/PathwayBrowser/#/R-XTR-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 IEA Xenopus tropicalis 5124 R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 5124 R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 5124 R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 5124 R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 5124 R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 5124 R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 5137 R-BTA-9707353 https://reactome.org/PathwayBrowser/#/R-BTA-9707353 CYP19A1 binds Aromatase inhibitors IEA Bos taurus 5137 R-CEL-9707353 https://reactome.org/PathwayBrowser/#/R-CEL-9707353 CYP19A1 binds Aromatase inhibitors IEA Caenorhabditis elegans 5137 R-CFA-9707353 https://reactome.org/PathwayBrowser/#/R-CFA-9707353 CYP19A1 binds Aromatase inhibitors IEA Canis familiaris 5137 R-DME-9707353 https://reactome.org/PathwayBrowser/#/R-DME-9707353 CYP19A1 binds Aromatase inhibitors IEA Drosophila melanogaster 5137 R-DRE-9707353 https://reactome.org/PathwayBrowser/#/R-DRE-9707353 CYP19A1 binds Aromatase inhibitors IEA Danio rerio 5137 R-GGA-9707353 https://reactome.org/PathwayBrowser/#/R-GGA-9707353 CYP19A1 binds Aromatase inhibitors IEA Gallus gallus 5137 R-HSA-9707353 https://reactome.org/PathwayBrowser/#/R-HSA-9707353 CYP19A1 binds Aromatase inhibitors TAS Homo sapiens 5137 R-MMU-9707353 https://reactome.org/PathwayBrowser/#/R-MMU-9707353 CYP19A1 binds Aromatase inhibitors IEA Mus musculus 5137 R-RNO-9707353 https://reactome.org/PathwayBrowser/#/R-RNO-9707353 CYP19A1 binds Aromatase inhibitors IEA Rattus norvegicus 5137 R-SSC-9707353 https://reactome.org/PathwayBrowser/#/R-SSC-9707353 CYP19A1 binds Aromatase inhibitors IEA Sus scrofa 5137 R-XTR-9707353 https://reactome.org/PathwayBrowser/#/R-XTR-9707353 CYP19A1 binds Aromatase inhibitors IEA Xenopus tropicalis 5141 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 5141 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 5141 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 5141 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 5141 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 5141 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 5141 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 5141 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 5141 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 5141 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 5144 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 5144 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 5144 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 5144 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 5144 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 5144 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 5144 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 5144 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 5146 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 5146 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 5146 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 5146 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 5146 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 5146 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 5146 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 5146 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 5146 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 5146 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 5158 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 5158 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 5158 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 5158 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 5158 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 5158 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 5158 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 5158 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 5158 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 5158 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 5158 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 5158 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 5158 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 5158 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 5158 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 5158 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 5158 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 5158 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 5158 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 5158 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 516 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 516 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 516 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 516 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 516 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 516 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 516 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 516 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 516 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 516 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 516 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 5168 R-BTA-9621179 https://reactome.org/PathwayBrowser/#/R-BTA-9621179 Cinaciguat binds sGC:NO IEA Bos taurus 5168 R-CFA-9621179 https://reactome.org/PathwayBrowser/#/R-CFA-9621179 Cinaciguat binds sGC:NO IEA Canis familiaris 5168 R-DME-9621179 https://reactome.org/PathwayBrowser/#/R-DME-9621179 Cinaciguat binds sGC:NO IEA Drosophila melanogaster 5168 R-DRE-9621179 https://reactome.org/PathwayBrowser/#/R-DRE-9621179 Cinaciguat binds sGC:NO IEA Danio rerio 5168 R-GGA-9621179 https://reactome.org/PathwayBrowser/#/R-GGA-9621179 Cinaciguat binds sGC:NO IEA Gallus gallus 5168 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 5168 R-HSA-9621179 https://reactome.org/PathwayBrowser/#/R-HSA-9621179 Cinaciguat binds sGC:NO TAS Homo sapiens 5168 R-MMU-9621179 https://reactome.org/PathwayBrowser/#/R-MMU-9621179 Cinaciguat binds sGC:NO IEA Mus musculus 5168 R-RNO-9621179 https://reactome.org/PathwayBrowser/#/R-RNO-9621179 Cinaciguat binds sGC:NO IEA Rattus norvegicus 5168 R-SSC-9621179 https://reactome.org/PathwayBrowser/#/R-SSC-9621179 Cinaciguat binds sGC:NO IEA Sus scrofa 5171 R-BTA-194023 https://reactome.org/PathwayBrowser/#/R-BTA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Bos taurus 5171 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 5171 R-CFA-194023 https://reactome.org/PathwayBrowser/#/R-CFA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Canis familiaris 5171 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 5171 R-DME-194023 https://reactome.org/PathwayBrowser/#/R-DME-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Drosophila melanogaster 5171 R-DRE-194023 https://reactome.org/PathwayBrowser/#/R-DRE-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Danio rerio 5171 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 5171 R-GGA-194023 https://reactome.org/PathwayBrowser/#/R-GGA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Gallus gallus 5171 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 5171 R-HSA-194023 https://reactome.org/PathwayBrowser/#/R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR TAS Homo sapiens 5171 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 5171 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 5171 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 5171 R-MMU-194023 https://reactome.org/PathwayBrowser/#/R-MMU-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Mus musculus 5171 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 5171 R-RNO-194023 https://reactome.org/PathwayBrowser/#/R-RNO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Rattus norvegicus 5171 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 5171 R-SPO-194023 https://reactome.org/PathwayBrowser/#/R-SPO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Schizosaccharomyces pombe 5171 R-SSC-194023 https://reactome.org/PathwayBrowser/#/R-SSC-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Sus scrofa 5171 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 5171 R-XTR-194023 https://reactome.org/PathwayBrowser/#/R-XTR-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Xenopus tropicalis 5195 R-BTA-1482543 https://reactome.org/PathwayBrowser/#/R-BTA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Bos taurus 5195 R-BTA-1482647 https://reactome.org/PathwayBrowser/#/R-BTA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Bos taurus 5195 R-BTA-1482654 https://reactome.org/PathwayBrowser/#/R-BTA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Bos taurus 5195 R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 5195 R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 5195 R-BTA-432049 https://reactome.org/PathwayBrowser/#/R-BTA-432049 Aquaporin-9 passively transports glycerol into cell IEA Bos taurus 5195 R-BTA-432074 https://reactome.org/PathwayBrowser/#/R-BTA-432074 Aquaporin-7 passively transports glycerol out of cell IEA Bos taurus 5195 R-BTA-507869 https://reactome.org/PathwayBrowser/#/R-BTA-507869 Aquaporins passively transport glycerol into cells IEA Bos taurus 5195 R-BTA-507871 https://reactome.org/PathwayBrowser/#/R-BTA-507871 Aquaporins passively transport glycerol out of cells IEA Bos taurus 5195 R-BTA-5694462 https://reactome.org/PathwayBrowser/#/R-BTA-5694462 ABHD6,12 hydrolyse 3AG IEA Bos taurus 5195 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 5195 R-BTA-75887 https://reactome.org/PathwayBrowser/#/R-BTA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Bos taurus 5195 R-BTA-8955794 https://reactome.org/PathwayBrowser/#/R-BTA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Bos taurus 5195 R-CEL-1482647 https://reactome.org/PathwayBrowser/#/R-CEL-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Caenorhabditis elegans 5195 R-CEL-1482654 https://reactome.org/PathwayBrowser/#/R-CEL-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Caenorhabditis elegans 5195 R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 5195 R-CEL-432049 https://reactome.org/PathwayBrowser/#/R-CEL-432049 Aquaporin-9 passively transports glycerol into cell IEA Caenorhabditis elegans 5195 R-CEL-432074 https://reactome.org/PathwayBrowser/#/R-CEL-432074 Aquaporin-7 passively transports glycerol out of cell IEA Caenorhabditis elegans 5195 R-CEL-507869 https://reactome.org/PathwayBrowser/#/R-CEL-507869 Aquaporins passively transport glycerol into cells IEA Caenorhabditis elegans 5195 R-CEL-507871 https://reactome.org/PathwayBrowser/#/R-CEL-507871 Aquaporins passively transport glycerol out of cells IEA Caenorhabditis elegans 5195 R-CEL-5694462 https://reactome.org/PathwayBrowser/#/R-CEL-5694462 ABHD6,12 hydrolyse 3AG IEA Caenorhabditis elegans 5195 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 5195 R-CEL-75887 https://reactome.org/PathwayBrowser/#/R-CEL-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Caenorhabditis elegans 5195 R-CEL-8955794 https://reactome.org/PathwayBrowser/#/R-CEL-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Caenorhabditis elegans 5195 R-CFA-1482543 https://reactome.org/PathwayBrowser/#/R-CFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Canis familiaris 5195 R-CFA-1482647 https://reactome.org/PathwayBrowser/#/R-CFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Canis familiaris 5195 R-CFA-1482654 https://reactome.org/PathwayBrowser/#/R-CFA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Canis familiaris 5195 R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 5195 R-CFA-432049 https://reactome.org/PathwayBrowser/#/R-CFA-432049 Aquaporin-9 passively transports glycerol into cell IEA Canis familiaris 5195 R-CFA-432074 https://reactome.org/PathwayBrowser/#/R-CFA-432074 Aquaporin-7 passively transports glycerol out of cell IEA Canis familiaris 5195 R-CFA-507869 https://reactome.org/PathwayBrowser/#/R-CFA-507869 Aquaporins passively transport glycerol into cells IEA Canis familiaris 5195 R-CFA-507871 https://reactome.org/PathwayBrowser/#/R-CFA-507871 Aquaporins passively transport glycerol out of cells IEA Canis familiaris 5195 R-CFA-5694462 https://reactome.org/PathwayBrowser/#/R-CFA-5694462 ABHD6,12 hydrolyse 3AG IEA Canis familiaris 5195 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 5195 R-CFA-75887 https://reactome.org/PathwayBrowser/#/R-CFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Canis familiaris 5195 R-CFA-8955794 https://reactome.org/PathwayBrowser/#/R-CFA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Canis familiaris 5195 R-DDI-1482543 https://reactome.org/PathwayBrowser/#/R-DDI-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Dictyostelium discoideum 5195 R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 5195 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 5195 R-DDI-75887 https://reactome.org/PathwayBrowser/#/R-DDI-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Dictyostelium discoideum 5195 R-DME-1482647 https://reactome.org/PathwayBrowser/#/R-DME-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Drosophila melanogaster 5195 R-DME-1482654 https://reactome.org/PathwayBrowser/#/R-DME-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Drosophila melanogaster 5195 R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 5195 R-DME-5694462 https://reactome.org/PathwayBrowser/#/R-DME-5694462 ABHD6,12 hydrolyse 3AG IEA Drosophila melanogaster 5195 R-DME-75887 https://reactome.org/PathwayBrowser/#/R-DME-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Drosophila melanogaster 5195 R-DME-8955794 https://reactome.org/PathwayBrowser/#/R-DME-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Drosophila melanogaster 5195 R-DRE-1482543 https://reactome.org/PathwayBrowser/#/R-DRE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Danio rerio 5195 R-DRE-1482647 https://reactome.org/PathwayBrowser/#/R-DRE-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Danio rerio 5195 R-DRE-1482654 https://reactome.org/PathwayBrowser/#/R-DRE-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Danio rerio 5195 R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 5195 R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 5195 R-DRE-432049 https://reactome.org/PathwayBrowser/#/R-DRE-432049 Aquaporin-9 passively transports glycerol into cell IEA Danio rerio 5195 R-DRE-507869 https://reactome.org/PathwayBrowser/#/R-DRE-507869 Aquaporins passively transport glycerol into cells IEA Danio rerio 5195 R-DRE-507871 https://reactome.org/PathwayBrowser/#/R-DRE-507871 Aquaporins passively transport glycerol out of cells IEA Danio rerio 5195 R-DRE-5694462 https://reactome.org/PathwayBrowser/#/R-DRE-5694462 ABHD6,12 hydrolyse 3AG IEA Danio rerio 5195 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 5195 R-DRE-8955794 https://reactome.org/PathwayBrowser/#/R-DRE-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Danio rerio 5195 R-GGA-1482543 https://reactome.org/PathwayBrowser/#/R-GGA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Gallus gallus 5195 R-GGA-1482647 https://reactome.org/PathwayBrowser/#/R-GGA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Gallus gallus 5195 R-GGA-1482654 https://reactome.org/PathwayBrowser/#/R-GGA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Gallus gallus 5195 R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 5195 R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 5195 R-GGA-432049 https://reactome.org/PathwayBrowser/#/R-GGA-432049 Aquaporin-9 passively transports glycerol into cell IEA Gallus gallus 5195 R-GGA-432074 https://reactome.org/PathwayBrowser/#/R-GGA-432074 Aquaporin-7 passively transports glycerol out of cell IEA Gallus gallus 5195 R-GGA-507869 https://reactome.org/PathwayBrowser/#/R-GGA-507869 Aquaporins passively transport glycerol into cells IEA Gallus gallus 5195 R-GGA-507871 https://reactome.org/PathwayBrowser/#/R-GGA-507871 Aquaporins passively transport glycerol out of cells IEA Gallus gallus 5195 R-GGA-5694462 https://reactome.org/PathwayBrowser/#/R-GGA-5694462 ABHD6,12 hydrolyse 3AG IEA Gallus gallus 5195 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 5195 R-GGA-75887 https://reactome.org/PathwayBrowser/#/R-GGA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Gallus gallus 5195 R-GGA-8955794 https://reactome.org/PathwayBrowser/#/R-GGA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Gallus gallus 5195 R-HSA-1482543 https://reactome.org/PathwayBrowser/#/R-HSA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL TAS Homo sapiens 5195 R-HSA-1482647 https://reactome.org/PathwayBrowser/#/R-HSA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 TAS Homo sapiens 5195 R-HSA-1482654 https://reactome.org/PathwayBrowser/#/R-HSA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 TAS Homo sapiens 5195 R-HSA-1483142 https://reactome.org/PathwayBrowser/#/R-HSA-1483142 PC is transphosphatidylated to PG by PLD1-4/6 IEA Homo sapiens 5195 R-HSA-163595 https://reactome.org/PathwayBrowser/#/R-HSA-163595 2-acylglycerol + H2O -> glycerol + fatty acid IEA Homo sapiens 5195 R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 5195 R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 5195 R-HSA-432049 https://reactome.org/PathwayBrowser/#/R-HSA-432049 Aquaporin-9 passively transports glycerol into cell TAS Homo sapiens 5195 R-HSA-432074 https://reactome.org/PathwayBrowser/#/R-HSA-432074 Aquaporin-7 passively transports glycerol out of cell TAS Homo sapiens 5195 R-HSA-507869 https://reactome.org/PathwayBrowser/#/R-HSA-507869 Aquaporins passively transport glycerol into cells TAS Homo sapiens 5195 R-HSA-507871 https://reactome.org/PathwayBrowser/#/R-HSA-507871 Aquaporins passively transport glycerol out of cells TAS Homo sapiens 5195 R-HSA-5694462 https://reactome.org/PathwayBrowser/#/R-HSA-5694462 ABHD6,12 hydrolyse 3AG TAS Homo sapiens 5195 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 5195 R-HSA-75887 https://reactome.org/PathwayBrowser/#/R-HSA-75887 Conversion of Glycerol to Glycerol-3-phosphate TAS Homo sapiens 5195 R-HSA-8955794 https://reactome.org/PathwayBrowser/#/R-HSA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol TAS Homo sapiens 5195 R-MMU-1482543 https://reactome.org/PathwayBrowser/#/R-MMU-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Mus musculus 5195 R-MMU-1482647 https://reactome.org/PathwayBrowser/#/R-MMU-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Mus musculus 5195 R-MMU-1482654 https://reactome.org/PathwayBrowser/#/R-MMU-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Mus musculus 5195 R-MMU-1483172 https://reactome.org/PathwayBrowser/#/R-MMU-1483172 PC is transphosphatidylated to PG by Pld1-4/6 TAS Mus musculus 5195 R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 5195 R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 5195 R-MMU-432049 https://reactome.org/PathwayBrowser/#/R-MMU-432049 Aquaporin-9 passively transports glycerol into cell IEA Mus musculus 5195 R-MMU-432074 https://reactome.org/PathwayBrowser/#/R-MMU-432074 Aquaporin-7 passively transports glycerol out of cell IEA Mus musculus 5195 R-MMU-507869 https://reactome.org/PathwayBrowser/#/R-MMU-507869 Aquaporins passively transport glycerol into cells IEA Mus musculus 5195 R-MMU-507871 https://reactome.org/PathwayBrowser/#/R-MMU-507871 Aquaporins passively transport glycerol out of cells IEA Mus musculus 5195 R-MMU-5694462 https://reactome.org/PathwayBrowser/#/R-MMU-5694462 ABHD6,12 hydrolyse 3AG IEA Mus musculus 5195 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 5195 R-MMU-75887 https://reactome.org/PathwayBrowser/#/R-MMU-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Mus musculus 5195 R-MMU-8955794 https://reactome.org/PathwayBrowser/#/R-MMU-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Mus musculus 5195 R-PFA-1482543 https://reactome.org/PathwayBrowser/#/R-PFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Plasmodium falciparum 5195 R-PFA-1482647 https://reactome.org/PathwayBrowser/#/R-PFA-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Plasmodium falciparum 5195 R-PFA-1482654 https://reactome.org/PathwayBrowser/#/R-PFA-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Plasmodium falciparum 5195 R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 5195 R-PFA-432049 https://reactome.org/PathwayBrowser/#/R-PFA-432049 Aquaporin-9 passively transports glycerol into cell IEA Plasmodium falciparum 5195 R-PFA-432074 https://reactome.org/PathwayBrowser/#/R-PFA-432074 Aquaporin-7 passively transports glycerol out of cell IEA Plasmodium falciparum 5195 R-PFA-507869 https://reactome.org/PathwayBrowser/#/R-PFA-507869 Aquaporins passively transport glycerol into cells IEA Plasmodium falciparum 5195 R-PFA-507871 https://reactome.org/PathwayBrowser/#/R-PFA-507871 Aquaporins passively transport glycerol out of cells IEA Plasmodium falciparum 5195 R-PFA-75887 https://reactome.org/PathwayBrowser/#/R-PFA-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Plasmodium falciparum 5195 R-RNO-1482543 https://reactome.org/PathwayBrowser/#/R-RNO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Rattus norvegicus 5195 R-RNO-1482647 https://reactome.org/PathwayBrowser/#/R-RNO-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Rattus norvegicus 5195 R-RNO-1482654 https://reactome.org/PathwayBrowser/#/R-RNO-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Rattus norvegicus 5195 R-RNO-163439 https://reactome.org/PathwayBrowser/#/R-RNO-163439 2-acylglycerol + H2O -> glycerol + fatty acid TAS Rattus norvegicus 5195 R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 5195 R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 5195 R-RNO-432049 https://reactome.org/PathwayBrowser/#/R-RNO-432049 Aquaporin-9 passively transports glycerol into cell IEA Rattus norvegicus 5195 R-RNO-432074 https://reactome.org/PathwayBrowser/#/R-RNO-432074 Aquaporin-7 passively transports glycerol out of cell IEA Rattus norvegicus 5195 R-RNO-507869 https://reactome.org/PathwayBrowser/#/R-RNO-507869 Aquaporins passively transport glycerol into cells IEA Rattus norvegicus 5195 R-RNO-507871 https://reactome.org/PathwayBrowser/#/R-RNO-507871 Aquaporins passively transport glycerol out of cells IEA Rattus norvegicus 5195 R-RNO-5694462 https://reactome.org/PathwayBrowser/#/R-RNO-5694462 ABHD6,12 hydrolyse 3AG IEA Rattus norvegicus 5195 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 5195 R-RNO-75887 https://reactome.org/PathwayBrowser/#/R-RNO-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Rattus norvegicus 5195 R-RNO-8955794 https://reactome.org/PathwayBrowser/#/R-RNO-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Rattus norvegicus 5195 R-SCE-1482543 https://reactome.org/PathwayBrowser/#/R-SCE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Saccharomyces cerevisiae 5195 R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 5195 R-SCE-432049 https://reactome.org/PathwayBrowser/#/R-SCE-432049 Aquaporin-9 passively transports glycerol into cell IEA Saccharomyces cerevisiae 5195 R-SCE-432074 https://reactome.org/PathwayBrowser/#/R-SCE-432074 Aquaporin-7 passively transports glycerol out of cell IEA Saccharomyces cerevisiae 5195 R-SCE-507869 https://reactome.org/PathwayBrowser/#/R-SCE-507869 Aquaporins passively transport glycerol into cells IEA Saccharomyces cerevisiae 5195 R-SCE-507871 https://reactome.org/PathwayBrowser/#/R-SCE-507871 Aquaporins passively transport glycerol out of cells IEA Saccharomyces cerevisiae 5195 R-SCE-5694462 https://reactome.org/PathwayBrowser/#/R-SCE-5694462 ABHD6,12 hydrolyse 3AG IEA Saccharomyces cerevisiae 5195 R-SCE-75887 https://reactome.org/PathwayBrowser/#/R-SCE-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Saccharomyces cerevisiae 5195 R-SPO-1482543 https://reactome.org/PathwayBrowser/#/R-SPO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Schizosaccharomyces pombe 5195 R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 5195 R-SPO-432049 https://reactome.org/PathwayBrowser/#/R-SPO-432049 Aquaporin-9 passively transports glycerol into cell IEA Schizosaccharomyces pombe 5195 R-SPO-432074 https://reactome.org/PathwayBrowser/#/R-SPO-432074 Aquaporin-7 passively transports glycerol out of cell IEA Schizosaccharomyces pombe 5195 R-SPO-507869 https://reactome.org/PathwayBrowser/#/R-SPO-507869 Aquaporins passively transport glycerol into cells IEA Schizosaccharomyces pombe 5195 R-SPO-507871 https://reactome.org/PathwayBrowser/#/R-SPO-507871 Aquaporins passively transport glycerol out of cells IEA Schizosaccharomyces pombe 5195 R-SSC-1482543 https://reactome.org/PathwayBrowser/#/R-SSC-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Sus scrofa 5195 R-SSC-1482647 https://reactome.org/PathwayBrowser/#/R-SSC-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Sus scrofa 5195 R-SSC-1482654 https://reactome.org/PathwayBrowser/#/R-SSC-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Sus scrofa 5195 R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 5195 R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 5195 R-SSC-432049 https://reactome.org/PathwayBrowser/#/R-SSC-432049 Aquaporin-9 passively transports glycerol into cell IEA Sus scrofa 5195 R-SSC-432074 https://reactome.org/PathwayBrowser/#/R-SSC-432074 Aquaporin-7 passively transports glycerol out of cell IEA Sus scrofa 5195 R-SSC-507869 https://reactome.org/PathwayBrowser/#/R-SSC-507869 Aquaporins passively transport glycerol into cells IEA Sus scrofa 5195 R-SSC-507871 https://reactome.org/PathwayBrowser/#/R-SSC-507871 Aquaporins passively transport glycerol out of cells IEA Sus scrofa 5195 R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa 5195 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 5195 R-SSC-75887 https://reactome.org/PathwayBrowser/#/R-SSC-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Sus scrofa 5195 R-SSC-8955794 https://reactome.org/PathwayBrowser/#/R-SSC-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Sus scrofa 5195 R-XTR-1482543 https://reactome.org/PathwayBrowser/#/R-XTR-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Xenopus tropicalis 5195 R-XTR-1482647 https://reactome.org/PathwayBrowser/#/R-XTR-1482647 2-MAG and DAG are transacylated to TAG by PNPLA2/3 IEA Xenopus tropicalis 5195 R-XTR-1482654 https://reactome.org/PathwayBrowser/#/R-XTR-1482654 2-MAG is transacylated to DAG by PNPLA2/3 IEA Xenopus tropicalis 5195 R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 5195 R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 5195 R-XTR-432049 https://reactome.org/PathwayBrowser/#/R-XTR-432049 Aquaporin-9 passively transports glycerol into cell IEA Xenopus tropicalis 5195 R-XTR-432074 https://reactome.org/PathwayBrowser/#/R-XTR-432074 Aquaporin-7 passively transports glycerol out of cell IEA Xenopus tropicalis 5195 R-XTR-507869 https://reactome.org/PathwayBrowser/#/R-XTR-507869 Aquaporins passively transport glycerol into cells IEA Xenopus tropicalis 5195 R-XTR-507871 https://reactome.org/PathwayBrowser/#/R-XTR-507871 Aquaporins passively transport glycerol out of cells IEA Xenopus tropicalis 5195 R-XTR-5694462 https://reactome.org/PathwayBrowser/#/R-XTR-5694462 ABHD6,12 hydrolyse 3AG IEA Xenopus tropicalis 5195 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 5195 R-XTR-75887 https://reactome.org/PathwayBrowser/#/R-XTR-75887 Conversion of Glycerol to Glycerol-3-phosphate IEA Xenopus tropicalis 5195 R-XTR-8955794 https://reactome.org/PathwayBrowser/#/R-XTR-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Xenopus tropicalis 520 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 520 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 520 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 520 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 520 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 520 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 520 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 520 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 520 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 520 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 520 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 5203 R-BTA-1855154 https://reactome.org/PathwayBrowser/#/R-BTA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 5203 R-CEL-1855154 https://reactome.org/PathwayBrowser/#/R-CEL-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 5203 R-CFA-1855154 https://reactome.org/PathwayBrowser/#/R-CFA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 5203 R-DDI-1855154 https://reactome.org/PathwayBrowser/#/R-DDI-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 5203 R-DME-1855154 https://reactome.org/PathwayBrowser/#/R-DME-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 5203 R-DRE-1855154 https://reactome.org/PathwayBrowser/#/R-DRE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 5203 R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 5203 R-HSA-1855154 https://reactome.org/PathwayBrowser/#/R-HSA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 5203 R-HSA-6809561 https://reactome.org/PathwayBrowser/#/R-HSA-6809561 I(1,3)P2 is dephosphorylated into I1P by MTMR7 IEA Homo sapiens 5203 R-HSA-6809565 https://reactome.org/PathwayBrowser/#/R-HSA-6809565 I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 IEA Homo sapiens 5203 R-MMU-1855154 https://reactome.org/PathwayBrowser/#/R-MMU-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 5203 R-MMU-6809624 https://reactome.org/PathwayBrowser/#/R-MMU-6809624 I(1,3)P2 is dephosphorylated into I1P by Mtmr7 TAS Mus musculus 5203 R-MMU-6809627 https://reactome.org/PathwayBrowser/#/R-MMU-6809627 I(1,3)P2 is dephosphorylated into I1P by Mtmr7:Mtmr9 TAS Mus musculus 5203 R-MTU-879298 https://reactome.org/PathwayBrowser/#/R-MTU-879298 acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate TAS Mycobacterium tuberculosis 5203 R-MTU-879331 https://reactome.org/PathwayBrowser/#/R-MTU-879331 glucose-6-phosphate is converted to inositol-1-phosphate TAS Mycobacterium tuberculosis 5203 R-RNO-1855154 https://reactome.org/PathwayBrowser/#/R-RNO-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 5203 R-SCE-1855154 https://reactome.org/PathwayBrowser/#/R-SCE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 5203 R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 5203 R-XTR-1855154 https://reactome.org/PathwayBrowser/#/R-XTR-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 5204 R-BTA-1855178 https://reactome.org/PathwayBrowser/#/R-BTA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Bos taurus 5204 R-BTA-1855202 https://reactome.org/PathwayBrowser/#/R-BTA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Bos taurus 5204 R-BTA-1855210 https://reactome.org/PathwayBrowser/#/R-BTA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 5204 R-CEL-1855178 https://reactome.org/PathwayBrowser/#/R-CEL-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Caenorhabditis elegans 5204 R-CEL-1855202 https://reactome.org/PathwayBrowser/#/R-CEL-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Caenorhabditis elegans 5204 R-CEL-1855210 https://reactome.org/PathwayBrowser/#/R-CEL-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 5204 R-CFA-1855202 https://reactome.org/PathwayBrowser/#/R-CFA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Canis familiaris 5204 R-CFA-1855210 https://reactome.org/PathwayBrowser/#/R-CFA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 5204 R-DDI-1855178 https://reactome.org/PathwayBrowser/#/R-DDI-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Dictyostelium discoideum 5204 R-DDI-1855210 https://reactome.org/PathwayBrowser/#/R-DDI-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 5204 R-DME-1855178 https://reactome.org/PathwayBrowser/#/R-DME-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Drosophila melanogaster 5204 R-DME-1855202 https://reactome.org/PathwayBrowser/#/R-DME-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Drosophila melanogaster 5204 R-DME-1855210 https://reactome.org/PathwayBrowser/#/R-DME-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 5204 R-DRE-1855202 https://reactome.org/PathwayBrowser/#/R-DRE-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Danio rerio 5204 R-DRE-1855210 https://reactome.org/PathwayBrowser/#/R-DRE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 5204 R-GGA-1855178 https://reactome.org/PathwayBrowser/#/R-GGA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Gallus gallus 5204 R-GGA-1855202 https://reactome.org/PathwayBrowser/#/R-GGA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Gallus gallus 5204 R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 5204 R-HSA-1855178 https://reactome.org/PathwayBrowser/#/R-HSA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol TAS Homo sapiens 5204 R-HSA-1855202 https://reactome.org/PathwayBrowser/#/R-HSA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol TAS Homo sapiens 5204 R-HSA-1855210 https://reactome.org/PathwayBrowser/#/R-HSA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 5204 R-MMU-1855178 https://reactome.org/PathwayBrowser/#/R-MMU-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Mus musculus 5204 R-MMU-1855202 https://reactome.org/PathwayBrowser/#/R-MMU-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Mus musculus 5204 R-MMU-1855210 https://reactome.org/PathwayBrowser/#/R-MMU-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 5204 R-PFA-1855178 https://reactome.org/PathwayBrowser/#/R-PFA-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Plasmodium falciparum 5204 R-RNO-1855178 https://reactome.org/PathwayBrowser/#/R-RNO-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Rattus norvegicus 5204 R-RNO-1855202 https://reactome.org/PathwayBrowser/#/R-RNO-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Rattus norvegicus 5204 R-RNO-1855210 https://reactome.org/PathwayBrowser/#/R-RNO-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 5204 R-SCE-1855178 https://reactome.org/PathwayBrowser/#/R-SCE-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Saccharomyces cerevisiae 5204 R-SCE-1855210 https://reactome.org/PathwayBrowser/#/R-SCE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 5204 R-SSC-1855178 https://reactome.org/PathwayBrowser/#/R-SSC-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Sus scrofa 5204 R-SSC-1855202 https://reactome.org/PathwayBrowser/#/R-SSC-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Sus scrofa 5204 R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 5204 R-XTR-1855178 https://reactome.org/PathwayBrowser/#/R-XTR-1855178 Glc6P is isomerised to I3P by ISYNA1 in the cytosol IEA Xenopus tropicalis 5204 R-XTR-1855202 https://reactome.org/PathwayBrowser/#/R-XTR-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Xenopus tropicalis 5204 R-XTR-1855210 https://reactome.org/PathwayBrowser/#/R-XTR-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 5205 R-BTA-1855208 https://reactome.org/PathwayBrowser/#/R-BTA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Bos taurus 5205 R-BTA-1855211 https://reactome.org/PathwayBrowser/#/R-BTA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 5205 R-CEL-1855211 https://reactome.org/PathwayBrowser/#/R-CEL-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 5205 R-CFA-1855208 https://reactome.org/PathwayBrowser/#/R-CFA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Canis familiaris 5205 R-CFA-1855211 https://reactome.org/PathwayBrowser/#/R-CFA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 5205 R-DDI-1855208 https://reactome.org/PathwayBrowser/#/R-DDI-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Dictyostelium discoideum 5205 R-DDI-1855211 https://reactome.org/PathwayBrowser/#/R-DDI-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 5205 R-DME-1855208 https://reactome.org/PathwayBrowser/#/R-DME-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Drosophila melanogaster 5205 R-DME-1855211 https://reactome.org/PathwayBrowser/#/R-DME-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 5205 R-DRE-1855211 https://reactome.org/PathwayBrowser/#/R-DRE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 5205 R-GGA-1855208 https://reactome.org/PathwayBrowser/#/R-GGA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Gallus gallus 5205 R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 5205 R-HSA-1855208 https://reactome.org/PathwayBrowser/#/R-HSA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol TAS Homo sapiens 5205 R-HSA-1855211 https://reactome.org/PathwayBrowser/#/R-HSA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 5205 R-MMU-1855208 https://reactome.org/PathwayBrowser/#/R-MMU-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Mus musculus 5205 R-MMU-1855211 https://reactome.org/PathwayBrowser/#/R-MMU-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 5205 R-RNO-1855208 https://reactome.org/PathwayBrowser/#/R-RNO-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Rattus norvegicus 5205 R-RNO-1855211 https://reactome.org/PathwayBrowser/#/R-RNO-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 5205 R-SCE-1855211 https://reactome.org/PathwayBrowser/#/R-SCE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 5205 R-SSC-1855208 https://reactome.org/PathwayBrowser/#/R-SSC-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Sus scrofa 5205 R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 5205 R-XTR-1855211 https://reactome.org/PathwayBrowser/#/R-XTR-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 5209 R-BTA-9707353 https://reactome.org/PathwayBrowser/#/R-BTA-9707353 CYP19A1 binds Aromatase inhibitors IEA Bos taurus 5209 R-CEL-9707353 https://reactome.org/PathwayBrowser/#/R-CEL-9707353 CYP19A1 binds Aromatase inhibitors IEA Caenorhabditis elegans 5209 R-CFA-9707353 https://reactome.org/PathwayBrowser/#/R-CFA-9707353 CYP19A1 binds Aromatase inhibitors IEA Canis familiaris 5209 R-DME-9707353 https://reactome.org/PathwayBrowser/#/R-DME-9707353 CYP19A1 binds Aromatase inhibitors IEA Drosophila melanogaster 5209 R-DRE-9707353 https://reactome.org/PathwayBrowser/#/R-DRE-9707353 CYP19A1 binds Aromatase inhibitors IEA Danio rerio 5209 R-GGA-9707353 https://reactome.org/PathwayBrowser/#/R-GGA-9707353 CYP19A1 binds Aromatase inhibitors IEA Gallus gallus 5209 R-HSA-9707353 https://reactome.org/PathwayBrowser/#/R-HSA-9707353 CYP19A1 binds Aromatase inhibitors TAS Homo sapiens 5209 R-MMU-9707353 https://reactome.org/PathwayBrowser/#/R-MMU-9707353 CYP19A1 binds Aromatase inhibitors IEA Mus musculus 5209 R-RNO-9707353 https://reactome.org/PathwayBrowser/#/R-RNO-9707353 CYP19A1 binds Aromatase inhibitors IEA Rattus norvegicus 5209 R-SSC-9707353 https://reactome.org/PathwayBrowser/#/R-SSC-9707353 CYP19A1 binds Aromatase inhibitors IEA Sus scrofa 5209 R-XTR-9707353 https://reactome.org/PathwayBrowser/#/R-XTR-9707353 CYP19A1 binds Aromatase inhibitors IEA Xenopus tropicalis 521 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 521 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 521 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 521 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 521 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 521 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 521 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 521 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 521 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 521 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 521 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 5212 R-BTA-425822 https://reactome.org/PathwayBrowser/#/R-BTA-425822 K+-independent Li+/Ca2+ exchanger transport IEA Bos taurus 5212 R-BTA-8953499 https://reactome.org/PathwayBrowser/#/R-BTA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Bos taurus 5212 R-CEL-425822 https://reactome.org/PathwayBrowser/#/R-CEL-425822 K+-independent Li+/Ca2+ exchanger transport IEA Caenorhabditis elegans 5212 R-CEL-8953499 https://reactome.org/PathwayBrowser/#/R-CEL-8953499 IMPAD1 hydrolyses PAP to AMP IEA Caenorhabditis elegans 5212 R-CFA-425822 https://reactome.org/PathwayBrowser/#/R-CFA-425822 K+-independent Li+/Ca2+ exchanger transport IEA Canis familiaris 5212 R-CFA-8953499 https://reactome.org/PathwayBrowser/#/R-CFA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Canis familiaris 5212 R-DDI-8953499 https://reactome.org/PathwayBrowser/#/R-DDI-8953499 IMPAD1 hydrolyses PAP to AMP IEA Dictyostelium discoideum 5212 R-DME-425822 https://reactome.org/PathwayBrowser/#/R-DME-425822 K+-independent Li+/Ca2+ exchanger transport IEA Drosophila melanogaster 5212 R-DME-8953499 https://reactome.org/PathwayBrowser/#/R-DME-8953499 IMPAD1 hydrolyses PAP to AMP IEA Drosophila melanogaster 5212 R-DRE-8953499 https://reactome.org/PathwayBrowser/#/R-DRE-8953499 IMPAD1 hydrolyses PAP to AMP IEA Danio rerio 5212 R-HSA-425822 https://reactome.org/PathwayBrowser/#/R-HSA-425822 K+-independent Li+/Ca2+ exchanger transport TAS Homo sapiens 5212 R-HSA-8953499 https://reactome.org/PathwayBrowser/#/R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP TAS Homo sapiens 5212 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5212 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5212 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5212 R-MMU-425822 https://reactome.org/PathwayBrowser/#/R-MMU-425822 K+-independent Li+/Ca2+ exchanger transport IEA Mus musculus 5212 R-MMU-8953499 https://reactome.org/PathwayBrowser/#/R-MMU-8953499 IMPAD1 hydrolyses PAP to AMP IEA Mus musculus 5212 R-RNO-425822 https://reactome.org/PathwayBrowser/#/R-RNO-425822 K+-independent Li+/Ca2+ exchanger transport IEA Rattus norvegicus 5212 R-RNO-8953499 https://reactome.org/PathwayBrowser/#/R-RNO-8953499 IMPAD1 hydrolyses PAP to AMP IEA Rattus norvegicus 5212 R-SCE-425822 https://reactome.org/PathwayBrowser/#/R-SCE-425822 K+-independent Li+/Ca2+ exchanger transport IEA Saccharomyces cerevisiae 5212 R-SPO-425822 https://reactome.org/PathwayBrowser/#/R-SPO-425822 K+-independent Li+/Ca2+ exchanger transport IEA Schizosaccharomyces pombe 5212 R-SSC-425822 https://reactome.org/PathwayBrowser/#/R-SSC-425822 K+-independent Li+/Ca2+ exchanger transport IEA Sus scrofa 5212 R-SSC-8953499 https://reactome.org/PathwayBrowser/#/R-SSC-8953499 IMPAD1 hydrolyses PAP to AMP IEA Sus scrofa 5212 R-XTR-8953499 https://reactome.org/PathwayBrowser/#/R-XTR-8953499 IMPAD1 hydrolyses PAP to AMP IEA Xenopus tropicalis 5215 R-BTA-9836702 https://reactome.org/PathwayBrowser/#/R-BTA-9836702 PKR inhibitors bind PKR IEA Bos taurus 5215 R-CEL-9836702 https://reactome.org/PathwayBrowser/#/R-CEL-9836702 PKR inhibitors bind PKR IEA Caenorhabditis elegans 5215 R-CFA-9836702 https://reactome.org/PathwayBrowser/#/R-CFA-9836702 PKR inhibitors bind PKR IEA Canis familiaris 5215 R-DME-9836702 https://reactome.org/PathwayBrowser/#/R-DME-9836702 PKR inhibitors bind PKR IEA Drosophila melanogaster 5215 R-DRE-9836702 https://reactome.org/PathwayBrowser/#/R-DRE-9836702 PKR inhibitors bind PKR IEA Danio rerio 5215 R-GGA-9836702 https://reactome.org/PathwayBrowser/#/R-GGA-9836702 PKR inhibitors bind PKR IEA Gallus gallus 5215 R-HSA-9833723 https://reactome.org/PathwayBrowser/#/R-HSA-9833723 PKR forms a dimer TAS Homo sapiens 5215 R-HSA-9836702 https://reactome.org/PathwayBrowser/#/R-HSA-9836702 PKR inhibitors bind PKR TAS Homo sapiens 5215 R-MMU-9836702 https://reactome.org/PathwayBrowser/#/R-MMU-9836702 PKR inhibitors bind PKR IEA Mus musculus 5215 R-RNO-9836702 https://reactome.org/PathwayBrowser/#/R-RNO-9836702 PKR inhibitors bind PKR IEA Rattus norvegicus 5215 R-SSC-9836702 https://reactome.org/PathwayBrowser/#/R-SSC-9836702 PKR inhibitors bind PKR IEA Sus scrofa 5215 R-XTR-9836702 https://reactome.org/PathwayBrowser/#/R-XTR-9836702 PKR inhibitors bind PKR IEA Xenopus tropicalis 522 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 522 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 522 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 522 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 522 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 522 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 522 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 522 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 522 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 522 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 522 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 5225 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 5225 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 5225 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 5225 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 5225 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 5225 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 5225 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 5225 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 5225 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 5225 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 5227 R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 5227 R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 5227 R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 5227 R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 5227 R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 5227 R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 5227 R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 5227 R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 5227 R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 5227 R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 5227 R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 5227 R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 5230 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 5230 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 5230 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 5230 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 5230 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 5230 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 5230 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 5230 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 5230 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 5230 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 5230 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 5230 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 5230 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 5230 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 5230 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 5230 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 5230 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 5230 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 5239 R-BTA-158468 https://reactome.org/PathwayBrowser/#/R-BTA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Bos taurus 5239 R-BTA-158546 https://reactome.org/PathwayBrowser/#/R-BTA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Bos taurus 5239 R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 5239 R-BTA-9677320 https://reactome.org/PathwayBrowser/#/R-BTA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Bos taurus 5239 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 5239 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 5239 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 5239 R-BTA-9753277 https://reactome.org/PathwayBrowser/#/R-BTA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Bos taurus 5239 R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 5239 R-CEL-158546 https://reactome.org/PathwayBrowser/#/R-CEL-158546 UGTs glucuronate APAP to APAP-GlcA IEA Caenorhabditis elegans 5239 R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 5239 R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 5239 R-CFA-158468 https://reactome.org/PathwayBrowser/#/R-CFA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Canis familiaris 5239 R-CFA-158546 https://reactome.org/PathwayBrowser/#/R-CFA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Canis familiaris 5239 R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 5239 R-CFA-9677320 https://reactome.org/PathwayBrowser/#/R-CFA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Canis familiaris 5239 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 5239 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 5239 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 5239 R-CFA-9753277 https://reactome.org/PathwayBrowser/#/R-CFA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Canis familiaris 5239 R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 5239 R-DDI-158546 https://reactome.org/PathwayBrowser/#/R-DDI-158546 UGTs glucuronate APAP to APAP-GlcA IEA Dictyostelium discoideum 5239 R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 5239 R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 5239 R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 5239 R-DME-158468 https://reactome.org/PathwayBrowser/#/R-DME-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Drosophila melanogaster 5239 R-DME-158546 https://reactome.org/PathwayBrowser/#/R-DME-158546 UGTs glucuronate APAP to APAP-GlcA IEA Drosophila melanogaster 5239 R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 5239 R-DME-9753277 https://reactome.org/PathwayBrowser/#/R-DME-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Drosophila melanogaster 5239 R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 5239 R-DRE-158468 https://reactome.org/PathwayBrowser/#/R-DRE-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Danio rerio 5239 R-DRE-158546 https://reactome.org/PathwayBrowser/#/R-DRE-158546 UGTs glucuronate APAP to APAP-GlcA IEA Danio rerio 5239 R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 5239 R-DRE-9677320 https://reactome.org/PathwayBrowser/#/R-DRE-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Danio rerio 5239 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 5239 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 5239 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 5239 R-DRE-9753277 https://reactome.org/PathwayBrowser/#/R-DRE-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Danio rerio 5239 R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 5239 R-GGA-158468 https://reactome.org/PathwayBrowser/#/R-GGA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Gallus gallus 5239 R-GGA-158546 https://reactome.org/PathwayBrowser/#/R-GGA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Gallus gallus 5239 R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 5239 R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 5239 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus 5239 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 5239 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 5239 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 5239 R-GGA-9753277 https://reactome.org/PathwayBrowser/#/R-GGA-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Gallus gallus 5239 R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 5239 R-HSA-158468 https://reactome.org/PathwayBrowser/#/R-HSA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 TAS Homo sapiens 5239 R-HSA-158546 https://reactome.org/PathwayBrowser/#/R-HSA-158546 UGTs glucuronate APAP to APAP-GlcA TAS Homo sapiens 5239 R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 5239 R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 5239 R-HSA-9677320 https://reactome.org/PathwayBrowser/#/R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors TAS Homo sapiens 5239 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 5239 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 5239 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 5239 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 5239 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 5239 R-HSA-9753277 https://reactome.org/PathwayBrowser/#/R-HSA-9753277 SULT dimers sulfate APAP to APAP-SO3 TAS Homo sapiens 5239 R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 5239 R-HSA-9754180 https://reactome.org/PathwayBrowser/#/R-HSA-9754180 APAP translocates from extracellular region to cytosol TAS Homo sapiens 5239 R-MMU-158468 https://reactome.org/PathwayBrowser/#/R-MMU-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Mus musculus 5239 R-MMU-158546 https://reactome.org/PathwayBrowser/#/R-MMU-158546 UGTs glucuronate APAP to APAP-GlcA IEA Mus musculus 5239 R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 5239 R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 5239 R-MMU-9677320 https://reactome.org/PathwayBrowser/#/R-MMU-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Mus musculus 5239 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 5239 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 5239 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 5239 R-MMU-9753277 https://reactome.org/PathwayBrowser/#/R-MMU-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Mus musculus 5239 R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 5239 R-RNO-158468 https://reactome.org/PathwayBrowser/#/R-RNO-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Rattus norvegicus 5239 R-RNO-158546 https://reactome.org/PathwayBrowser/#/R-RNO-158546 UGTs glucuronate APAP to APAP-GlcA IEA Rattus norvegicus 5239 R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 5239 R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 5239 R-RNO-9677320 https://reactome.org/PathwayBrowser/#/R-RNO-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Rattus norvegicus 5239 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 5239 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 5239 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 5239 R-RNO-9753277 https://reactome.org/PathwayBrowser/#/R-RNO-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Rattus norvegicus 5239 R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 5239 R-SSC-158468 https://reactome.org/PathwayBrowser/#/R-SSC-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Sus scrofa 5239 R-SSC-158546 https://reactome.org/PathwayBrowser/#/R-SSC-158546 UGTs glucuronate APAP to APAP-GlcA IEA Sus scrofa 5239 R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 5239 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa 5239 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 5239 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 5239 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 5239 R-SSC-9753277 https://reactome.org/PathwayBrowser/#/R-SSC-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Sus scrofa 5239 R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 5239 R-XTR-158468 https://reactome.org/PathwayBrowser/#/R-XTR-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 IEA Xenopus tropicalis 5239 R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 5239 R-XTR-9677320 https://reactome.org/PathwayBrowser/#/R-XTR-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Xenopus tropicalis 5239 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 5239 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 5239 R-XTR-9753277 https://reactome.org/PathwayBrowser/#/R-XTR-9753277 SULT dimers sulfate APAP to APAP-SO3 IEA Xenopus tropicalis 5239 R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 5257 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 5257 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 5257 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 5257 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 5257 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 5257 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 5257 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 5257 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 5257 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 5257 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 5260 R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 5260 R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 5260 R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 5260 R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 5260 R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 5260 R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 5260 R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 5260 R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 5260 R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 5260 R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 5260 R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 5276 R-BTA-1474146 https://reactome.org/PathwayBrowser/#/R-BTA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Bos taurus 5276 R-BTA-1475414 https://reactome.org/PathwayBrowser/#/R-BTA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Bos taurus 5276 R-BTA-1497784 https://reactome.org/PathwayBrowser/#/R-BTA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Bos taurus 5276 R-BTA-1497796 https://reactome.org/PathwayBrowser/#/R-BTA-1497796 BH2 binding can lead to eNOS uncoupling IEA Bos taurus 5276 R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 5276 R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 5276 R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 5276 R-BTA-202132 https://reactome.org/PathwayBrowser/#/R-BTA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Bos taurus 5276 R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 Depalmitoylation of eNOS IEA Bos taurus 5276 R-BTA-203625 https://reactome.org/PathwayBrowser/#/R-BTA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Bos taurus 5276 R-BTA-203680 https://reactome.org/PathwayBrowser/#/R-BTA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Bos taurus 5276 R-BTA-209823 https://reactome.org/PathwayBrowser/#/R-BTA-209823 Tyrosine is hydroxylated to dopa IEA Bos taurus 5276 R-BTA-209828 https://reactome.org/PathwayBrowser/#/R-BTA-209828 Tryptophan is hydroxylated IEA Bos taurus 5276 R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 5276 R-BTA-71118 https://reactome.org/PathwayBrowser/#/R-BTA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Bos taurus 5276 R-BTA-71130 https://reactome.org/PathwayBrowser/#/R-BTA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Bos taurus 5276 R-BTA-9860808 https://reactome.org/PathwayBrowser/#/R-BTA-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Bos taurus 5276 R-BTA-9861318 https://reactome.org/PathwayBrowser/#/R-BTA-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Bos taurus 5276 R-CEL-1474146 https://reactome.org/PathwayBrowser/#/R-CEL-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Caenorhabditis elegans 5276 R-CEL-1497784 https://reactome.org/PathwayBrowser/#/R-CEL-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Caenorhabditis elegans 5276 R-CEL-1497796 https://reactome.org/PathwayBrowser/#/R-CEL-1497796 BH2 binding can lead to eNOS uncoupling IEA Caenorhabditis elegans 5276 R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 5276 R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 5276 R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 5276 R-CEL-209823 https://reactome.org/PathwayBrowser/#/R-CEL-209823 Tyrosine is hydroxylated to dopa IEA Caenorhabditis elegans 5276 R-CEL-209828 https://reactome.org/PathwayBrowser/#/R-CEL-209828 Tryptophan is hydroxylated IEA Caenorhabditis elegans 5276 R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 5276 R-CEL-71118 https://reactome.org/PathwayBrowser/#/R-CEL-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Caenorhabditis elegans 5276 R-CEL-71130 https://reactome.org/PathwayBrowser/#/R-CEL-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Caenorhabditis elegans 5276 R-CFA-1474146 https://reactome.org/PathwayBrowser/#/R-CFA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Canis familiaris 5276 R-CFA-1475414 https://reactome.org/PathwayBrowser/#/R-CFA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Canis familiaris 5276 R-CFA-203625 https://reactome.org/PathwayBrowser/#/R-CFA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Canis familiaris 5276 R-CFA-209823 https://reactome.org/PathwayBrowser/#/R-CFA-209823 Tyrosine is hydroxylated to dopa IEA Canis familiaris 5276 R-CFA-209828 https://reactome.org/PathwayBrowser/#/R-CFA-209828 Tryptophan is hydroxylated IEA Canis familiaris 5276 R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 5276 R-CFA-71118 https://reactome.org/PathwayBrowser/#/R-CFA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Canis familiaris 5276 R-CFA-71130 https://reactome.org/PathwayBrowser/#/R-CFA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Canis familiaris 5276 R-DDI-1474146 https://reactome.org/PathwayBrowser/#/R-DDI-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Dictyostelium discoideum 5276 R-DDI-1475414 https://reactome.org/PathwayBrowser/#/R-DDI-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Dictyostelium discoideum 5276 R-DDI-1497784 https://reactome.org/PathwayBrowser/#/R-DDI-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Dictyostelium discoideum 5276 R-DDI-1497796 https://reactome.org/PathwayBrowser/#/R-DDI-1497796 BH2 binding can lead to eNOS uncoupling IEA Dictyostelium discoideum 5276 R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 5276 R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 5276 R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 5276 R-DDI-202132 https://reactome.org/PathwayBrowser/#/R-DDI-202132 depalmitoylated eNOS translocates from plasma membrane IEA Dictyostelium discoideum 5276 R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 Depalmitoylation of eNOS IEA Dictyostelium discoideum 5276 R-DDI-203680 https://reactome.org/PathwayBrowser/#/R-DDI-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Dictyostelium discoideum 5276 R-DDI-209823 https://reactome.org/PathwayBrowser/#/R-DDI-209823 Tyrosine is hydroxylated to dopa IEA Dictyostelium discoideum 5276 R-DDI-209828 https://reactome.org/PathwayBrowser/#/R-DDI-209828 Tryptophan is hydroxylated IEA Dictyostelium discoideum 5276 R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 5276 R-DDI-71118 https://reactome.org/PathwayBrowser/#/R-DDI-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Dictyostelium discoideum 5276 R-DDI-71130 https://reactome.org/PathwayBrowser/#/R-DDI-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Dictyostelium discoideum 5276 R-DDI-9860792 https://reactome.org/PathwayBrowser/#/R-DDI-9860792 Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 IEA Dictyostelium discoideum 5276 R-DDI-9860808 https://reactome.org/PathwayBrowser/#/R-DDI-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Dictyostelium discoideum 5276 R-DME-1474146 https://reactome.org/PathwayBrowser/#/R-DME-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Drosophila melanogaster 5276 R-DME-1475414 https://reactome.org/PathwayBrowser/#/R-DME-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Drosophila melanogaster 5276 R-DME-1497784 https://reactome.org/PathwayBrowser/#/R-DME-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Drosophila melanogaster 5276 R-DME-1497796 https://reactome.org/PathwayBrowser/#/R-DME-1497796 BH2 binding can lead to eNOS uncoupling IEA Drosophila melanogaster 5276 R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 5276 R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 5276 R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 5276 R-DME-202132 https://reactome.org/PathwayBrowser/#/R-DME-202132 depalmitoylated eNOS translocates from plasma membrane IEA Drosophila melanogaster 5276 R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 Depalmitoylation of eNOS IEA Drosophila melanogaster 5276 R-DME-203680 https://reactome.org/PathwayBrowser/#/R-DME-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Drosophila melanogaster 5276 R-DME-209823 https://reactome.org/PathwayBrowser/#/R-DME-209823 Tyrosine is hydroxylated to dopa IEA Drosophila melanogaster 5276 R-DME-209828 https://reactome.org/PathwayBrowser/#/R-DME-209828 Tryptophan is hydroxylated IEA Drosophila melanogaster 5276 R-DME-71118 https://reactome.org/PathwayBrowser/#/R-DME-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Drosophila melanogaster 5276 R-DME-71130 https://reactome.org/PathwayBrowser/#/R-DME-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Drosophila melanogaster 5276 R-DME-9860792 https://reactome.org/PathwayBrowser/#/R-DME-9860792 Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 IEA Drosophila melanogaster 5276 R-DME-9860808 https://reactome.org/PathwayBrowser/#/R-DME-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Drosophila melanogaster 5276 R-DME-9861318 https://reactome.org/PathwayBrowser/#/R-DME-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Drosophila melanogaster 5276 R-DRE-1475414 https://reactome.org/PathwayBrowser/#/R-DRE-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Danio rerio 5276 R-DRE-203625 https://reactome.org/PathwayBrowser/#/R-DRE-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Danio rerio 5276 R-DRE-209823 https://reactome.org/PathwayBrowser/#/R-DRE-209823 Tyrosine is hydroxylated to dopa IEA Danio rerio 5276 R-DRE-209828 https://reactome.org/PathwayBrowser/#/R-DRE-209828 Tryptophan is hydroxylated IEA Danio rerio 5276 R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 5276 R-DRE-71118 https://reactome.org/PathwayBrowser/#/R-DRE-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Danio rerio 5276 R-DRE-71130 https://reactome.org/PathwayBrowser/#/R-DRE-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Danio rerio 5276 R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus 5276 R-GGA-1475414 https://reactome.org/PathwayBrowser/#/R-GGA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Gallus gallus 5276 R-GGA-1497784 https://reactome.org/PathwayBrowser/#/R-GGA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Gallus gallus 5276 R-GGA-1497796 https://reactome.org/PathwayBrowser/#/R-GGA-1497796 BH2 binding can lead to eNOS uncoupling IEA Gallus gallus 5276 R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 5276 R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 5276 R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 5276 R-GGA-202132 https://reactome.org/PathwayBrowser/#/R-GGA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Gallus gallus 5276 R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 Depalmitoylation of eNOS IEA Gallus gallus 5276 R-GGA-203625 https://reactome.org/PathwayBrowser/#/R-GGA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Gallus gallus 5276 R-GGA-209823 https://reactome.org/PathwayBrowser/#/R-GGA-209823 Tyrosine is hydroxylated to dopa IEA Gallus gallus 5276 R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus 5276 R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 5276 R-GGA-71118 https://reactome.org/PathwayBrowser/#/R-GGA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Gallus gallus 5276 R-GGA-71130 https://reactome.org/PathwayBrowser/#/R-GGA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Gallus gallus 5276 R-GGA-9860792 https://reactome.org/PathwayBrowser/#/R-GGA-9860792 Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 IEA Gallus gallus 5276 R-GGA-9860808 https://reactome.org/PathwayBrowser/#/R-GGA-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Gallus gallus 5276 R-GGA-9861318 https://reactome.org/PathwayBrowser/#/R-GGA-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Gallus gallus 5276 R-HSA-1474146 https://reactome.org/PathwayBrowser/#/R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate TAS Homo sapiens 5276 R-HSA-1475414 https://reactome.org/PathwayBrowser/#/R-HSA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) TAS Homo sapiens 5276 R-HSA-1497784 https://reactome.org/PathwayBrowser/#/R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle TAS Homo sapiens 5276 R-HSA-1497794 https://reactome.org/PathwayBrowser/#/R-HSA-1497794 Salvage - BH2 is reduced to BH4 by DHFR IEA Homo sapiens 5276 R-HSA-1497796 https://reactome.org/PathwayBrowser/#/R-HSA-1497796 BH2 binding can lead to eNOS uncoupling TAS Homo sapiens 5276 R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 5276 R-HSA-1497824 https://reactome.org/PathwayBrowser/#/R-HSA-1497824 BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle TAS Homo sapiens 5276 R-HSA-1497855 https://reactome.org/PathwayBrowser/#/R-HSA-1497855 Ascorbate can reduce the BH3 radical back to BH4 TAS Homo sapiens 5276 R-HSA-1497866 https://reactome.org/PathwayBrowser/#/R-HSA-1497866 Peroxynitrite can oxidise BH4 to the BH3 radical TAS Homo sapiens 5276 R-HSA-1497883 https://reactome.org/PathwayBrowser/#/R-HSA-1497883 Ferrous iron reduces the BH3 radical back to BH4 TAS Homo sapiens 5276 R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 5276 R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 5276 R-HSA-202132 https://reactome.org/PathwayBrowser/#/R-HSA-202132 depalmitoylated eNOS translocates from plasma membrane TAS Homo sapiens 5276 R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 Depalmitoylation of eNOS TAS Homo sapiens 5276 R-HSA-203625 https://reactome.org/PathwayBrowser/#/R-HSA-203625 NOSTRIN mediated translocation of eNOS from plasma membrane TAS Homo sapiens 5276 R-HSA-203680 https://reactome.org/PathwayBrowser/#/R-HSA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments TAS Homo sapiens 5276 R-HSA-209823 https://reactome.org/PathwayBrowser/#/R-HSA-209823 Tyrosine is hydroxylated to dopa TAS Homo sapiens 5276 R-HSA-209828 https://reactome.org/PathwayBrowser/#/R-HSA-209828 Tryptophan is hydroxylated TAS Homo sapiens 5276 R-HSA-5649483 https://reactome.org/PathwayBrowser/#/R-HSA-5649483 Defective PAH does not hydroxylate L-Phe to L-Tyr TAS Homo sapiens 5276 R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 5276 R-HSA-71118 https://reactome.org/PathwayBrowser/#/R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr TAS Homo sapiens 5276 R-HSA-71130 https://reactome.org/PathwayBrowser/#/R-HSA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ TAS Homo sapiens 5276 R-HSA-9860792 https://reactome.org/PathwayBrowser/#/R-HSA-9860792 Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 TAS Homo sapiens 5276 R-HSA-9860808 https://reactome.org/PathwayBrowser/#/R-HSA-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 TAS Homo sapiens 5276 R-HSA-9861318 https://reactome.org/PathwayBrowser/#/R-HSA-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 TAS Homo sapiens 5276 R-MMU-1474146 https://reactome.org/PathwayBrowser/#/R-MMU-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Mus musculus 5276 R-MMU-1475414 https://reactome.org/PathwayBrowser/#/R-MMU-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Mus musculus 5276 R-MMU-1497770 https://reactome.org/PathwayBrowser/#/R-MMU-1497770 Salvage - BH2 is reduced to BH4 by Dhfr TAS Mus musculus 5276 R-MMU-1497784 https://reactome.org/PathwayBrowser/#/R-MMU-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Mus musculus 5276 R-MMU-1497796 https://reactome.org/PathwayBrowser/#/R-MMU-1497796 BH2 binding can lead to eNOS uncoupling IEA Mus musculus 5276 R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 5276 R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 5276 R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 5276 R-MMU-202132 https://reactome.org/PathwayBrowser/#/R-MMU-202132 depalmitoylated eNOS translocates from plasma membrane IEA Mus musculus 5276 R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 Depalmitoylation of eNOS IEA Mus musculus 5276 R-MMU-203625 https://reactome.org/PathwayBrowser/#/R-MMU-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Mus musculus 5276 R-MMU-203680 https://reactome.org/PathwayBrowser/#/R-MMU-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Mus musculus 5276 R-MMU-209823 https://reactome.org/PathwayBrowser/#/R-MMU-209823 Tyrosine is hydroxylated to dopa IEA Mus musculus 5276 R-MMU-209828 https://reactome.org/PathwayBrowser/#/R-MMU-209828 Tryptophan is hydroxylated IEA Mus musculus 5276 R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 5276 R-MMU-71118 https://reactome.org/PathwayBrowser/#/R-MMU-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Mus musculus 5276 R-MMU-71130 https://reactome.org/PathwayBrowser/#/R-MMU-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Mus musculus 5276 R-MMU-9860792 https://reactome.org/PathwayBrowser/#/R-MMU-9860792 Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 IEA Mus musculus 5276 R-MMU-9860808 https://reactome.org/PathwayBrowser/#/R-MMU-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Mus musculus 5276 R-MMU-9861318 https://reactome.org/PathwayBrowser/#/R-MMU-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Mus musculus 5276 R-PFA-1497784 https://reactome.org/PathwayBrowser/#/R-PFA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Plasmodium falciparum 5276 R-PFA-1497796 https://reactome.org/PathwayBrowser/#/R-PFA-1497796 BH2 binding can lead to eNOS uncoupling IEA Plasmodium falciparum 5276 R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 5276 R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 5276 R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 5276 R-PFA-202132 https://reactome.org/PathwayBrowser/#/R-PFA-202132 depalmitoylated eNOS translocates from plasma membrane IEA Plasmodium falciparum 5276 R-PFA-203680 https://reactome.org/PathwayBrowser/#/R-PFA-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Plasmodium falciparum 5276 R-RNO-1474146 https://reactome.org/PathwayBrowser/#/R-RNO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Rattus norvegicus 5276 R-RNO-1475414 https://reactome.org/PathwayBrowser/#/R-RNO-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Rattus norvegicus 5276 R-RNO-1497784 https://reactome.org/PathwayBrowser/#/R-RNO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Rattus norvegicus 5276 R-RNO-1497796 https://reactome.org/PathwayBrowser/#/R-RNO-1497796 BH2 binding can lead to eNOS uncoupling IEA Rattus norvegicus 5276 R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 5276 R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 5276 R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 5276 R-RNO-202132 https://reactome.org/PathwayBrowser/#/R-RNO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Rattus norvegicus 5276 R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 Depalmitoylation of eNOS IEA Rattus norvegicus 5276 R-RNO-203625 https://reactome.org/PathwayBrowser/#/R-RNO-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Rattus norvegicus 5276 R-RNO-203680 https://reactome.org/PathwayBrowser/#/R-RNO-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Rattus norvegicus 5276 R-RNO-209823 https://reactome.org/PathwayBrowser/#/R-RNO-209823 Tyrosine is hydroxylated to dopa IEA Rattus norvegicus 5276 R-RNO-209828 https://reactome.org/PathwayBrowser/#/R-RNO-209828 Tryptophan is hydroxylated IEA Rattus norvegicus 5276 R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 5276 R-RNO-71118 https://reactome.org/PathwayBrowser/#/R-RNO-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Rattus norvegicus 5276 R-RNO-71130 https://reactome.org/PathwayBrowser/#/R-RNO-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Rattus norvegicus 5276 R-RNO-9860792 https://reactome.org/PathwayBrowser/#/R-RNO-9860792 Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 IEA Rattus norvegicus 5276 R-RNO-9860808 https://reactome.org/PathwayBrowser/#/R-RNO-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Rattus norvegicus 5276 R-RNO-9861318 https://reactome.org/PathwayBrowser/#/R-RNO-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Rattus norvegicus 5276 R-SCE-1474146 https://reactome.org/PathwayBrowser/#/R-SCE-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Saccharomyces cerevisiae 5276 R-SCE-1497784 https://reactome.org/PathwayBrowser/#/R-SCE-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Saccharomyces cerevisiae 5276 R-SCE-1497796 https://reactome.org/PathwayBrowser/#/R-SCE-1497796 BH2 binding can lead to eNOS uncoupling IEA Saccharomyces cerevisiae 5276 R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 5276 R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 5276 R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 5276 R-SCE-202132 https://reactome.org/PathwayBrowser/#/R-SCE-202132 depalmitoylated eNOS translocates from plasma membrane IEA Saccharomyces cerevisiae 5276 R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 Depalmitoylation of eNOS IEA Saccharomyces cerevisiae 5276 R-SCE-9860792 https://reactome.org/PathwayBrowser/#/R-SCE-9860792 Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 IEA Saccharomyces cerevisiae 5276 R-SCE-9860808 https://reactome.org/PathwayBrowser/#/R-SCE-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Saccharomyces cerevisiae 5276 R-SCE-9861318 https://reactome.org/PathwayBrowser/#/R-SCE-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Saccharomyces cerevisiae 5276 R-SPO-1474146 https://reactome.org/PathwayBrowser/#/R-SPO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Schizosaccharomyces pombe 5276 R-SPO-1497784 https://reactome.org/PathwayBrowser/#/R-SPO-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Schizosaccharomyces pombe 5276 R-SPO-1497796 https://reactome.org/PathwayBrowser/#/R-SPO-1497796 BH2 binding can lead to eNOS uncoupling IEA Schizosaccharomyces pombe 5276 R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 5276 R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 5276 R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 5276 R-SPO-202132 https://reactome.org/PathwayBrowser/#/R-SPO-202132 depalmitoylated eNOS translocates from plasma membrane IEA Schizosaccharomyces pombe 5276 R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 Depalmitoylation of eNOS IEA Schizosaccharomyces pombe 5276 R-SPO-9860792 https://reactome.org/PathwayBrowser/#/R-SPO-9860792 Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 IEA Schizosaccharomyces pombe 5276 R-SPO-9860808 https://reactome.org/PathwayBrowser/#/R-SPO-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Schizosaccharomyces pombe 5276 R-SPO-9861318 https://reactome.org/PathwayBrowser/#/R-SPO-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Schizosaccharomyces pombe 5276 R-SSC-1474146 https://reactome.org/PathwayBrowser/#/R-SSC-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Sus scrofa 5276 R-SSC-1475414 https://reactome.org/PathwayBrowser/#/R-SSC-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Sus scrofa 5276 R-SSC-1497784 https://reactome.org/PathwayBrowser/#/R-SSC-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle IEA Sus scrofa 5276 R-SSC-1497796 https://reactome.org/PathwayBrowser/#/R-SSC-1497796 BH2 binding can lead to eNOS uncoupling IEA Sus scrofa 5276 R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 5276 R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 5276 R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 5276 R-SSC-202132 https://reactome.org/PathwayBrowser/#/R-SSC-202132 depalmitoylated eNOS translocates from plasma membrane IEA Sus scrofa 5276 R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 Depalmitoylation of eNOS IEA Sus scrofa 5276 R-SSC-203625 https://reactome.org/PathwayBrowser/#/R-SSC-203625 NOSTRIN mediated translocation of eNOS from plasma membrane IEA Sus scrofa 5276 R-SSC-203680 https://reactome.org/PathwayBrowser/#/R-SSC-203680 eNOS:NOSIP translocation from caveolae to intracellular compartments IEA Sus scrofa 5276 R-SSC-209823 https://reactome.org/PathwayBrowser/#/R-SSC-209823 Tyrosine is hydroxylated to dopa IEA Sus scrofa 5276 R-SSC-209828 https://reactome.org/PathwayBrowser/#/R-SSC-209828 Tryptophan is hydroxylated IEA Sus scrofa 5276 R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 5276 R-SSC-71118 https://reactome.org/PathwayBrowser/#/R-SSC-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Sus scrofa 5276 R-SSC-71130 https://reactome.org/PathwayBrowser/#/R-SSC-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Sus scrofa 5276 R-SSC-9860808 https://reactome.org/PathwayBrowser/#/R-SSC-9860808 p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 IEA Sus scrofa 5276 R-SSC-9861318 https://reactome.org/PathwayBrowser/#/R-SSC-9861318 PKA phosphorylates NOS3 (eNOS) on serine-633 IEA Sus scrofa 5276 R-XTR-1474146 https://reactome.org/PathwayBrowser/#/R-XTR-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Xenopus tropicalis 5276 R-XTR-1475414 https://reactome.org/PathwayBrowser/#/R-XTR-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) IEA Xenopus tropicalis 5276 R-XTR-209823 https://reactome.org/PathwayBrowser/#/R-XTR-209823 Tyrosine is hydroxylated to dopa IEA Xenopus tropicalis 5276 R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 5276 R-XTR-71118 https://reactome.org/PathwayBrowser/#/R-XTR-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Xenopus tropicalis 5276 R-XTR-71130 https://reactome.org/PathwayBrowser/#/R-XTR-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Xenopus tropicalis 5281 R-BTA-9677917 https://reactome.org/PathwayBrowser/#/R-BTA-9677917 MAOA inhibitors bind MAOA:FAD IEA Bos taurus 5281 R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus 5281 R-CFA-9677917 https://reactome.org/PathwayBrowser/#/R-CFA-9677917 MAOA inhibitors bind MAOA:FAD IEA Canis familiaris 5281 R-CFA-9677929 https://reactome.org/PathwayBrowser/#/R-CFA-9677929 MAOB inhibitors bind MAOB:FAD IEA Canis familiaris 5281 R-DDI-9677917 https://reactome.org/PathwayBrowser/#/R-DDI-9677917 MAOA inhibitors bind MAOA:FAD IEA Dictyostelium discoideum 5281 R-DDI-9677929 https://reactome.org/PathwayBrowser/#/R-DDI-9677929 MAOB inhibitors bind MAOB:FAD IEA Dictyostelium discoideum 5281 R-DRE-9677929 https://reactome.org/PathwayBrowser/#/R-DRE-9677929 MAOB inhibitors bind MAOB:FAD IEA Danio rerio 5281 R-GGA-9677917 https://reactome.org/PathwayBrowser/#/R-GGA-9677917 MAOA inhibitors bind MAOA:FAD IEA Gallus gallus 5281 R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus 5281 R-HSA-9677917 https://reactome.org/PathwayBrowser/#/R-HSA-9677917 MAOA inhibitors bind MAOA:FAD TAS Homo sapiens 5281 R-HSA-9677929 https://reactome.org/PathwayBrowser/#/R-HSA-9677929 MAOB inhibitors bind MAOB:FAD TAS Homo sapiens 5281 R-MMU-9677917 https://reactome.org/PathwayBrowser/#/R-MMU-9677917 MAOA inhibitors bind MAOA:FAD IEA Mus musculus 5281 R-MMU-9677929 https://reactome.org/PathwayBrowser/#/R-MMU-9677929 MAOB inhibitors bind MAOB:FAD IEA Mus musculus 5281 R-RNO-9677917 https://reactome.org/PathwayBrowser/#/R-RNO-9677917 MAOA inhibitors bind MAOA:FAD IEA Rattus norvegicus 5281 R-RNO-9677929 https://reactome.org/PathwayBrowser/#/R-RNO-9677929 MAOB inhibitors bind MAOB:FAD IEA Rattus norvegicus 5281 R-SSC-9677917 https://reactome.org/PathwayBrowser/#/R-SSC-9677917 MAOA inhibitors bind MAOA:FAD IEA Sus scrofa 5281 R-SSC-9677929 https://reactome.org/PathwayBrowser/#/R-SSC-9677929 MAOB inhibitors bind MAOB:FAD IEA Sus scrofa 5281 R-XTR-9677929 https://reactome.org/PathwayBrowser/#/R-XTR-9677929 MAOB inhibitors bind MAOB:FAD IEA Xenopus tropicalis 5291 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 5291 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 5291 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 5291 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 5291 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 5291 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 5291 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 5291 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 5291 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 5291 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 5297 R-BTA-9707186 https://reactome.org/PathwayBrowser/#/R-BTA-9707186 ALOX5 binds ALOX5 inhibitors IEA Bos taurus 5297 R-CFA-9707186 https://reactome.org/PathwayBrowser/#/R-CFA-9707186 ALOX5 binds ALOX5 inhibitors IEA Canis familiaris 5297 R-DDI-9707186 https://reactome.org/PathwayBrowser/#/R-DDI-9707186 ALOX5 binds ALOX5 inhibitors IEA Dictyostelium discoideum 5297 R-GGA-9707186 https://reactome.org/PathwayBrowser/#/R-GGA-9707186 ALOX5 binds ALOX5 inhibitors IEA Gallus gallus 5297 R-HSA-9707186 https://reactome.org/PathwayBrowser/#/R-HSA-9707186 ALOX5 binds ALOX5 inhibitors TAS Homo sapiens 5297 R-MMU-9707186 https://reactome.org/PathwayBrowser/#/R-MMU-9707186 ALOX5 binds ALOX5 inhibitors IEA Mus musculus 5297 R-RNO-9707186 https://reactome.org/PathwayBrowser/#/R-RNO-9707186 ALOX5 binds ALOX5 inhibitors IEA Rattus norvegicus 5297 R-SSC-9707186 https://reactome.org/PathwayBrowser/#/R-SSC-9707186 ALOX5 binds ALOX5 inhibitors IEA Sus scrofa 5297 R-XTR-9707186 https://reactome.org/PathwayBrowser/#/R-XTR-9707186 ALOX5 binds ALOX5 inhibitors IEA Xenopus tropicalis 5325 R-BTA-71275 https://reactome.org/PathwayBrowser/#/R-BTA-71275 arginine + glycine => ornithine + guanidoacetate IEA Bos taurus 5325 R-BTA-71286 https://reactome.org/PathwayBrowser/#/R-BTA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Bos taurus 5325 R-CFA-71275 https://reactome.org/PathwayBrowser/#/R-CFA-71275 arginine + glycine => ornithine + guanidoacetate IEA Canis familiaris 5325 R-CFA-71286 https://reactome.org/PathwayBrowser/#/R-CFA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Canis familiaris 5325 R-DRE-71275 https://reactome.org/PathwayBrowser/#/R-DRE-71275 arginine + glycine => ornithine + guanidoacetate IEA Danio rerio 5325 R-DRE-71286 https://reactome.org/PathwayBrowser/#/R-DRE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Danio rerio 5325 R-GGA-71275 https://reactome.org/PathwayBrowser/#/R-GGA-71275 arginine + glycine => ornithine + guanidoacetate IEA Gallus gallus 5325 R-GGA-71286 https://reactome.org/PathwayBrowser/#/R-GGA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Gallus gallus 5325 R-HSA-71275 https://reactome.org/PathwayBrowser/#/R-HSA-71275 arginine + glycine => ornithine + guanidoacetate TAS Homo sapiens 5325 R-HSA-71286 https://reactome.org/PathwayBrowser/#/R-HSA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine TAS Homo sapiens 5325 R-MMU-71275 https://reactome.org/PathwayBrowser/#/R-MMU-71275 arginine + glycine => ornithine + guanidoacetate IEA Mus musculus 5325 R-MMU-71286 https://reactome.org/PathwayBrowser/#/R-MMU-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Mus musculus 5325 R-RNO-71275 https://reactome.org/PathwayBrowser/#/R-RNO-71275 arginine + glycine => ornithine + guanidoacetate IEA Rattus norvegicus 5325 R-RNO-71286 https://reactome.org/PathwayBrowser/#/R-RNO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Rattus norvegicus 5325 R-SCE-71286 https://reactome.org/PathwayBrowser/#/R-SCE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Saccharomyces cerevisiae 5325 R-SPO-71286 https://reactome.org/PathwayBrowser/#/R-SPO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Schizosaccharomyces pombe 5325 R-SSC-71275 https://reactome.org/PathwayBrowser/#/R-SSC-71275 arginine + glycine => ornithine + guanidoacetate IEA Sus scrofa 5325 R-SSC-71286 https://reactome.org/PathwayBrowser/#/R-SSC-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Sus scrofa 5325 R-XTR-71275 https://reactome.org/PathwayBrowser/#/R-XTR-71275 arginine + glycine => ornithine + guanidoacetate IEA Xenopus tropicalis 5325 R-XTR-71286 https://reactome.org/PathwayBrowser/#/R-XTR-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Xenopus tropicalis 5326 R-HSA-9911461 https://reactome.org/PathwayBrowser/#/R-HSA-9911461 β-lactam antibiotics bind MrcB TAS Homo sapiens 5326 R-HSA-9911463 https://reactome.org/PathwayBrowser/#/R-HSA-9911463 MrcB elongates peptidoglycan TAS Homo sapiens 5326 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 5326 R-HSA-9911513 https://reactome.org/PathwayBrowser/#/R-HSA-9911513 BlaSHV-12 hydrolyzes ceftriaxone TAS Homo sapiens 5326 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 5326 R-HSA-9914083 https://reactome.org/PathwayBrowser/#/R-HSA-9914083 MdtE:MdtF:TolC exports beta-lactams to extracellular space TAS Homo sapiens 5326 R-HSA-9914089 https://reactome.org/PathwayBrowser/#/R-HSA-9914089 MdtE:MdtF:TolC exports beta-lactams to the periplasm TAS Homo sapiens 534 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 534 R-BTA-9611721 https://reactome.org/PathwayBrowser/#/R-BTA-9611721 β1-agonists bind ADRB1 IEA Bos taurus 534 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 534 R-DME-9611721 https://reactome.org/PathwayBrowser/#/R-DME-9611721 β1-agonists bind ADRB1 IEA Drosophila melanogaster 534 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 534 R-DRE-9611721 https://reactome.org/PathwayBrowser/#/R-DRE-9611721 β1-agonists bind ADRB1 IEA Danio rerio 534 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 534 R-GGA-9611721 https://reactome.org/PathwayBrowser/#/R-GGA-9611721 β1-agonists bind ADRB1 IEA Gallus gallus 534 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 534 R-HSA-9611721 https://reactome.org/PathwayBrowser/#/R-HSA-9611721 β1-agonists bind ADRB1 TAS Homo sapiens 534 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 534 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 534 R-MMU-9611721 https://reactome.org/PathwayBrowser/#/R-MMU-9611721 β1-agonists bind ADRB1 IEA Mus musculus 534 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 534 R-RNO-9611721 https://reactome.org/PathwayBrowser/#/R-RNO-9611721 β1-agonists bind ADRB1 IEA Rattus norvegicus 534 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 534 R-SSC-9611721 https://reactome.org/PathwayBrowser/#/R-SSC-9611721 β1-agonists bind ADRB1 IEA Sus scrofa 534 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 534 R-XTR-9611721 https://reactome.org/PathwayBrowser/#/R-XTR-9611721 β1-agonists bind ADRB1 IEA Xenopus tropicalis 5343 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 5346 R-BTA-8953398 https://reactome.org/PathwayBrowser/#/R-BTA-8953398 PIR oxygenates quercetin IEA Bos taurus 5346 R-CFA-8953398 https://reactome.org/PathwayBrowser/#/R-CFA-8953398 PIR oxygenates quercetin IEA Canis familiaris 5346 R-DDI-8953398 https://reactome.org/PathwayBrowser/#/R-DDI-8953398 PIR oxygenates quercetin IEA Dictyostelium discoideum 5346 R-HSA-8953398 https://reactome.org/PathwayBrowser/#/R-HSA-8953398 PIR oxygenates quercetin TAS Homo sapiens 5346 R-MMU-8953398 https://reactome.org/PathwayBrowser/#/R-MMU-8953398 PIR oxygenates quercetin IEA Mus musculus 5346 R-RNO-8953398 https://reactome.org/PathwayBrowser/#/R-RNO-8953398 PIR oxygenates quercetin IEA Rattus norvegicus 5346 R-SSC-8953398 https://reactome.org/PathwayBrowser/#/R-SSC-8953398 PIR oxygenates quercetin IEA Sus scrofa 5346 R-XTR-8953398 https://reactome.org/PathwayBrowser/#/R-XTR-8953398 PIR oxygenates quercetin IEA Xenopus tropicalis 535 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 535 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 535 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 535 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 535 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 535 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 535 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 535 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 535 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 535 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 535 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 535 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 535 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 535 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 535 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 535 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 535 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 535 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 535 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 535 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 535 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 535 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 535 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 535 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 535 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 535 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 535 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 535 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 535 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 536 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 536 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 536 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 536 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 536 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 536 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 536 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 536 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 536 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 536 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 536 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 536 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 536 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 536 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 536 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 536 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 536 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 536 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 536 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 536 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 536 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 536 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 536 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 536 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 536 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 536 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 536 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 536 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 536 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 537 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 537 R-BTA-9611721 https://reactome.org/PathwayBrowser/#/R-BTA-9611721 β1-agonists bind ADRB1 IEA Bos taurus 537 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 537 R-DME-9611721 https://reactome.org/PathwayBrowser/#/R-DME-9611721 β1-agonists bind ADRB1 IEA Drosophila melanogaster 537 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 537 R-DRE-9611721 https://reactome.org/PathwayBrowser/#/R-DRE-9611721 β1-agonists bind ADRB1 IEA Danio rerio 537 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 537 R-GGA-9611721 https://reactome.org/PathwayBrowser/#/R-GGA-9611721 β1-agonists bind ADRB1 IEA Gallus gallus 537 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 537 R-HSA-9611721 https://reactome.org/PathwayBrowser/#/R-HSA-9611721 β1-agonists bind ADRB1 TAS Homo sapiens 537 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 537 R-MMU-9611721 https://reactome.org/PathwayBrowser/#/R-MMU-9611721 β1-agonists bind ADRB1 IEA Mus musculus 537 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 537 R-RNO-9611721 https://reactome.org/PathwayBrowser/#/R-RNO-9611721 β1-agonists bind ADRB1 IEA Rattus norvegicus 537 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 537 R-SSC-9611721 https://reactome.org/PathwayBrowser/#/R-SSC-9611721 β1-agonists bind ADRB1 IEA Sus scrofa 537 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 537 R-XTR-9611721 https://reactome.org/PathwayBrowser/#/R-XTR-9611721 β1-agonists bind ADRB1 IEA Xenopus tropicalis 538 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 538 R-BTA-9611721 https://reactome.org/PathwayBrowser/#/R-BTA-9611721 β1-agonists bind ADRB1 IEA Bos taurus 538 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 538 R-DME-9611721 https://reactome.org/PathwayBrowser/#/R-DME-9611721 β1-agonists bind ADRB1 IEA Drosophila melanogaster 538 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 538 R-DRE-9611721 https://reactome.org/PathwayBrowser/#/R-DRE-9611721 β1-agonists bind ADRB1 IEA Danio rerio 538 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 538 R-GGA-9611721 https://reactome.org/PathwayBrowser/#/R-GGA-9611721 β1-agonists bind ADRB1 IEA Gallus gallus 538 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 538 R-HSA-9611721 https://reactome.org/PathwayBrowser/#/R-HSA-9611721 β1-agonists bind ADRB1 TAS Homo sapiens 538 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 538 R-MMU-9611721 https://reactome.org/PathwayBrowser/#/R-MMU-9611721 β1-agonists bind ADRB1 IEA Mus musculus 538 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 538 R-RNO-9611721 https://reactome.org/PathwayBrowser/#/R-RNO-9611721 β1-agonists bind ADRB1 IEA Rattus norvegicus 538 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 538 R-SSC-9611721 https://reactome.org/PathwayBrowser/#/R-SSC-9611721 β1-agonists bind ADRB1 IEA Sus scrofa 538 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 538 R-XTR-9611721 https://reactome.org/PathwayBrowser/#/R-XTR-9611721 β1-agonists bind ADRB1 IEA Xenopus tropicalis 54 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 54 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 54 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 54 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 54 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 54 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 54 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 54 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 54 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 54 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 5411 R-BTA-189069 https://reactome.org/PathwayBrowser/#/R-BTA-189069 sucrose + H2O => glucose + fructose IEA Bos taurus 5411 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 5411 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 5411 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 5411 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 5411 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 5411 R-CEL-189069 https://reactome.org/PathwayBrowser/#/R-CEL-189069 sucrose + H2O => glucose + fructose IEA Caenorhabditis elegans 5411 R-CFA-189069 https://reactome.org/PathwayBrowser/#/R-CFA-189069 sucrose + H2O => glucose + fructose IEA Canis familiaris 5411 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 5411 R-DDI-189069 https://reactome.org/PathwayBrowser/#/R-DDI-189069 sucrose + H2O => glucose + fructose IEA Dictyostelium discoideum 5411 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 5411 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 5411 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 5411 R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus 5411 R-HSA-189069 https://reactome.org/PathwayBrowser/#/R-HSA-189069 sucrose + H2O => glucose + fructose TAS Homo sapiens 5411 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 5411 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 5411 R-HSA-5659926 https://reactome.org/PathwayBrowser/#/R-HSA-5659926 Defective SI does not hydrolyze Suc IEA Homo sapiens 5411 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 5411 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 5411 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 5411 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 5411 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 5411 R-MMU-189069 https://reactome.org/PathwayBrowser/#/R-MMU-189069 sucrose + H2O => glucose + fructose IEA Mus musculus 5411 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 5411 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 5411 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 5411 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 5411 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 5411 R-RNO-189069 https://reactome.org/PathwayBrowser/#/R-RNO-189069 sucrose + H2O => glucose + fructose IEA Rattus norvegicus 5411 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 5411 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 5411 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 5411 R-SPO-189069 https://reactome.org/PathwayBrowser/#/R-SPO-189069 sucrose + H2O => glucose + fructose IEA Schizosaccharomyces pombe 5411 R-SSC-189069 https://reactome.org/PathwayBrowser/#/R-SSC-189069 sucrose + H2O => glucose + fructose IEA Sus scrofa 5411 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 5411 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 5411 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 5411 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 5411 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 5432 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 5432 R-BTA-444606 https://reactome.org/PathwayBrowser/#/R-BTA-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Bos taurus 5432 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 5432 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 5432 R-BTA-9728723 https://reactome.org/PathwayBrowser/#/R-BTA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Bos taurus 5432 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 5432 R-CFA-9728723 https://reactome.org/PathwayBrowser/#/R-CFA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Canis familiaris 5432 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 5432 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 5432 R-DRE-444606 https://reactome.org/PathwayBrowser/#/R-DRE-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Danio rerio 5432 R-DRE-9728723 https://reactome.org/PathwayBrowser/#/R-DRE-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Danio rerio 5432 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 5432 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 5432 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 5432 R-HSA-444606 https://reactome.org/PathwayBrowser/#/R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor TAS Homo sapiens 5432 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 5432 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 5432 R-HSA-9728697 https://reactome.org/PathwayBrowser/#/R-HSA-9728697 GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 5432 R-HSA-9728723 https://reactome.org/PathwayBrowser/#/R-HSA-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) TAS Homo sapiens 5432 R-HSA-9728729 https://reactome.org/PathwayBrowser/#/R-HSA-9728729 TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 IEA Homo sapiens 5432 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 5432 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 5432 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 5432 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 5432 R-MMU-444606 https://reactome.org/PathwayBrowser/#/R-MMU-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Mus musculus 5432 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 5432 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 5432 R-MMU-9728723 https://reactome.org/PathwayBrowser/#/R-MMU-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Mus musculus 5432 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 5432 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 5432 R-RNO-444606 https://reactome.org/PathwayBrowser/#/R-RNO-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Rattus norvegicus 5432 R-RNO-9728723 https://reactome.org/PathwayBrowser/#/R-RNO-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Rattus norvegicus 5432 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 5432 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 5432 R-SSC-444606 https://reactome.org/PathwayBrowser/#/R-SSC-444606 T1R2/T1R3 dimer is a sweet taste receptor IEA Sus scrofa 5432 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 5432 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 5432 R-SSC-9728723 https://reactome.org/PathwayBrowser/#/R-SSC-9728723 Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) IEA Sus scrofa 5432 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 5433 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 5433 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 5433 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 5433 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 5433 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 5433 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 5433 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 5433 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 5433 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 5433 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 5443 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 5443 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 5443 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 5443 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 5443 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 5443 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 5443 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 5443 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 5443 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 5443 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 5443 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 5451 R-BTA-209792 https://reactome.org/PathwayBrowser/#/R-BTA-209792 N-acetylation of serotonin IEA Bos taurus 5451 R-BTA-209821 https://reactome.org/PathwayBrowser/#/R-BTA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Bos taurus 5451 R-CFA-209792 https://reactome.org/PathwayBrowser/#/R-CFA-209792 N-acetylation of serotonin IEA Canis familiaris 5451 R-CFA-209821 https://reactome.org/PathwayBrowser/#/R-CFA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Canis familiaris 5451 R-DDI-209821 https://reactome.org/PathwayBrowser/#/R-DDI-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Dictyostelium discoideum 5451 R-DRE-209792 https://reactome.org/PathwayBrowser/#/R-DRE-209792 N-acetylation of serotonin IEA Danio rerio 5451 R-DRE-209821 https://reactome.org/PathwayBrowser/#/R-DRE-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Danio rerio 5451 R-GGA-209792 https://reactome.org/PathwayBrowser/#/R-GGA-209792 N-acetylation of serotonin IEA Gallus gallus 5451 R-GGA-209821 https://reactome.org/PathwayBrowser/#/R-GGA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Gallus gallus 5451 R-HSA-209792 https://reactome.org/PathwayBrowser/#/R-HSA-209792 N-acetylation of serotonin TAS Homo sapiens 5451 R-HSA-209821 https://reactome.org/PathwayBrowser/#/R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin TAS Homo sapiens 5451 R-MMU-209792 https://reactome.org/PathwayBrowser/#/R-MMU-209792 N-acetylation of serotonin IEA Mus musculus 5451 R-MMU-209821 https://reactome.org/PathwayBrowser/#/R-MMU-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Mus musculus 5451 R-RNO-209792 https://reactome.org/PathwayBrowser/#/R-RNO-209792 N-acetylation of serotonin IEA Rattus norvegicus 5451 R-RNO-209821 https://reactome.org/PathwayBrowser/#/R-RNO-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Rattus norvegicus 5451 R-SCE-209792 https://reactome.org/PathwayBrowser/#/R-SCE-209792 N-acetylation of serotonin IEA Saccharomyces cerevisiae 5451 R-SPO-209792 https://reactome.org/PathwayBrowser/#/R-SPO-209792 N-acetylation of serotonin IEA Schizosaccharomyces pombe 5451 R-SSC-209792 https://reactome.org/PathwayBrowser/#/R-SSC-209792 N-acetylation of serotonin IEA Sus scrofa 5451 R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa 5451 R-XTR-209821 https://reactome.org/PathwayBrowser/#/R-XTR-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Xenopus tropicalis 5472 R-BTA-432164 https://reactome.org/PathwayBrowser/#/R-BTA-432164 Ca2+ influx into the post-synaptic cell IEA Bos taurus 5472 R-CEL-432164 https://reactome.org/PathwayBrowser/#/R-CEL-432164 Ca2+ influx into the post-synaptic cell IEA Caenorhabditis elegans 5472 R-CFA-432164 https://reactome.org/PathwayBrowser/#/R-CFA-432164 Ca2+ influx into the post-synaptic cell IEA Canis familiaris 5472 R-DME-432164 https://reactome.org/PathwayBrowser/#/R-DME-432164 Ca2+ influx into the post-synaptic cell IEA Drosophila melanogaster 5472 R-DRE-432164 https://reactome.org/PathwayBrowser/#/R-DRE-432164 Ca2+ influx into the post-synaptic cell IEA Danio rerio 5472 R-GGA-432164 https://reactome.org/PathwayBrowser/#/R-GGA-432164 Ca2+ influx into the post-synaptic cell IEA Gallus gallus 5472 R-HSA-432164 https://reactome.org/PathwayBrowser/#/R-HSA-432164 Ca2+ influx into the post-synaptic cell TAS Homo sapiens 5472 R-MMU-432164 https://reactome.org/PathwayBrowser/#/R-MMU-432164 Ca2+ influx into the post-synaptic cell IEA Mus musculus 5472 R-RNO-432164 https://reactome.org/PathwayBrowser/#/R-RNO-432164 Ca2+ influx into the post-synaptic cell IEA Rattus norvegicus 5472 R-SSC-432164 https://reactome.org/PathwayBrowser/#/R-SSC-432164 Ca2+ influx into the post-synaptic cell IEA Sus scrofa 5472 R-XTR-432164 https://reactome.org/PathwayBrowser/#/R-XTR-432164 Ca2+ influx into the post-synaptic cell IEA Xenopus tropicalis 548 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 548 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 548 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 548 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 548 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 548 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 548 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 548 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 548 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 548 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 548 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 548 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 548 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 548 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 548 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 548 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 548 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 548 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 548 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 548 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 548 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 548 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 548 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 548 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 548 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 548 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 548 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 548 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 548 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 548 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 548 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 548 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 548 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 548 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 548 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 548 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 548 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 5487 R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 5487 R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 5487 R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 5487 R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 5487 R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 5487 R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 5487 R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 5488 R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 5488 R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 5488 R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 5488 R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 5488 R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 5488 R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 5488 R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 549 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 549 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 549 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 549 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 549 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 549 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 549 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 549 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 549 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 549 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 549 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 549 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 549 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 549 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 549 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 549 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 549 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 549 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 549 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 549 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 549 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 549 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 549 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 549 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 549 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 549 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 549 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 549 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 549 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 549 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 549 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 549 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 549 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 549 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 549 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 549 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 549 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 550 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 550 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 550 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 550 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 550 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 550 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 550 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 550 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 550 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 550 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 550 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 550 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 550 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 550 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 550 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 550 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 550 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 550 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 550 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 550 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 550 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 550 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 550 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 550 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 550 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 550 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 550 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 550 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 550 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 550 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 550 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 550 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 550 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 550 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 550 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 550 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 550 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 5501 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 5501 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 5501 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 5501 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 5501 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 5501 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 5501 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 5501 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 5501 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 5501 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 551 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 551 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 551 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 551 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 551 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 551 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 551 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 551 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 551 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 551 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 551 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 551 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 551 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 551 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 551 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 551 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 551 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 551 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 551 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 551 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 551 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 551 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 551 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 551 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 551 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 551 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 551 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 551 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 551 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 551 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 551 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 551 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 551 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 551 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 551 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 551 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 551 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 552 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 552 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 552 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 552 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 552 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 552 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 552 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 552 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 552 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 552 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 552 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 552 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 552 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 552 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 552 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 552 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 552 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 552 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 552 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 552 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 552 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 552 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 552 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 552 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 552 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 552 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 552 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 552 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 552 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 552 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 552 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 552 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 552 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 552 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 552 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 552 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 552 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 5521 R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 5521 R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 5521 R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 5521 R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 5521 R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 5521 R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 5521 R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 5521 R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 5521 R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 5521 R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 5521 R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 5521 R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 553 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 553 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 553 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 553 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 553 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 553 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 553 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 553 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 553 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 553 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 553 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 553 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 553 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 553 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 553 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 553 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 553 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 553 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 553 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 553 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 553 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 553 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 553 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 553 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 553 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 553 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 553 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 553 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 553 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 553 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 553 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 553 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 553 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 553 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 553 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 553 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 553 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 5532 R-HSA-5210912 https://reactome.org/PathwayBrowser/#/R-HSA-5210912 Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) TAS Homo sapiens 5532 R-HSA-5210935 https://reactome.org/PathwayBrowser/#/R-HSA-5210935 Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) TAS Homo sapiens 5532 R-HSA-9683546 https://reactome.org/PathwayBrowser/#/R-HSA-9683546 FURIN binds furin inhibitors TAS Homo sapiens 5535 R-BTA-597628 https://reactome.org/PathwayBrowser/#/R-BTA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Bos taurus 5535 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 5535 R-CEL-597628 https://reactome.org/PathwayBrowser/#/R-CEL-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Caenorhabditis elegans 5535 R-CFA-597628 https://reactome.org/PathwayBrowser/#/R-CFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Canis familiaris 5535 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 5535 R-DRE-597628 https://reactome.org/PathwayBrowser/#/R-DRE-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Danio rerio 5535 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 5535 R-GGA-597628 https://reactome.org/PathwayBrowser/#/R-GGA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Gallus gallus 5535 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 5535 R-HSA-5625574 https://reactome.org/PathwayBrowser/#/R-HSA-5625574 Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+ TAS Homo sapiens 5535 R-HSA-597628 https://reactome.org/PathwayBrowser/#/R-HSA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ TAS Homo sapiens 5535 R-HSA-9683467 https://reactome.org/PathwayBrowser/#/R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ TAS Homo sapiens 5535 R-HSA-9683478 https://reactome.org/PathwayBrowser/#/R-HSA-9683478 CQ, HCQ diffuses from cytosol to endocytic vesicle lumen TAS Homo sapiens 5535 R-HSA-9683488 https://reactome.org/PathwayBrowser/#/R-HSA-9683488 ACE2 is glycosylated to glycosylated-ACE2 TAS Homo sapiens 5535 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 5535 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 5535 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 5535 R-MMU-597628 https://reactome.org/PathwayBrowser/#/R-MMU-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Mus musculus 5535 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 5535 R-PFA-597628 https://reactome.org/PathwayBrowser/#/R-PFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Plasmodium falciparum 5535 R-RNO-597628 https://reactome.org/PathwayBrowser/#/R-RNO-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Rattus norvegicus 5535 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 5535 R-SSC-597628 https://reactome.org/PathwayBrowser/#/R-SSC-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Sus scrofa 5535 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 5535 R-XTR-597628 https://reactome.org/PathwayBrowser/#/R-XTR-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Xenopus tropicalis 554 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 554 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 554 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 554 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 554 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 554 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 554 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 554 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 554 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 554 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 554 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 554 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 554 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 554 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 554 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 554 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 554 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 554 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 554 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 554 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 554 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 554 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 554 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 554 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 554 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 554 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 554 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 554 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 554 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 554 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 554 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 554 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 554 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 554 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 554 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 554 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 554 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 5547 R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 5547 R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 5547 R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 5547 R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 5547 R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 5547 R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 5547 R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 5547 R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 5547 R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 5547 R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 5547 R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 5547 R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 5547 R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 5547 R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 5547 R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 5547 R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 5547 R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 5547 R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 5547 R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 5547 R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 5547 R-HSA-444191 https://reactome.org/PathwayBrowser/#/R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids IEA Homo sapiens 5547 R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 5547 R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 5547 R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 5547 R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 5547 R-MMU-444204 https://reactome.org/PathwayBrowser/#/R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids TAS Mus musculus 5547 R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 5547 R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 5547 R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 5547 R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 5547 R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 5547 R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 5547 R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 5547 R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 5547 R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 555 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 555 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 555 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 555 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 555 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 555 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 555 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 555 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 555 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 555 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 555 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 555 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 555 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 555 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 555 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 555 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 555 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 555 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 555 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 555 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 555 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 555 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 555 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 555 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 555 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 555 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 555 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 555 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 555 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 555 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 555 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 555 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 555 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 555 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 555 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 555 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 555 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 5567 R-BTA-9843117 https://reactome.org/PathwayBrowser/#/R-BTA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Bos taurus 5567 R-BTA-9843118 https://reactome.org/PathwayBrowser/#/R-BTA-9843118 RXRA binds ligands IEA Bos taurus 5567 R-BTA-9843120 https://reactome.org/PathwayBrowser/#/R-BTA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Bos taurus 5567 R-CFA-9843117 https://reactome.org/PathwayBrowser/#/R-CFA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Canis familiaris 5567 R-CFA-9843118 https://reactome.org/PathwayBrowser/#/R-CFA-9843118 RXRA binds ligands IEA Canis familiaris 5567 R-CFA-9843120 https://reactome.org/PathwayBrowser/#/R-CFA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Canis familiaris 5567 R-DME-9843117 https://reactome.org/PathwayBrowser/#/R-DME-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Drosophila melanogaster 5567 R-DME-9843118 https://reactome.org/PathwayBrowser/#/R-DME-9843118 RXRA binds ligands IEA Drosophila melanogaster 5567 R-DME-9843120 https://reactome.org/PathwayBrowser/#/R-DME-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Drosophila melanogaster 5567 R-DRE-9843118 https://reactome.org/PathwayBrowser/#/R-DRE-9843118 RXRA binds ligands IEA Danio rerio 5567 R-GGA-9843117 https://reactome.org/PathwayBrowser/#/R-GGA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Gallus gallus 5567 R-GGA-9843118 https://reactome.org/PathwayBrowser/#/R-GGA-9843118 RXRA binds ligands IEA Gallus gallus 5567 R-GGA-9843120 https://reactome.org/PathwayBrowser/#/R-GGA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Gallus gallus 5567 R-HSA-1183003 https://reactome.org/PathwayBrowser/#/R-HSA-1183003 Expression of Leptin TAS Homo sapiens 5567 R-HSA-1183058 https://reactome.org/PathwayBrowser/#/R-HSA-1183058 Expression of Adiponectin TAS Homo sapiens 5567 R-HSA-381309 https://reactome.org/PathwayBrowser/#/R-HSA-381309 PPARG:RXRA heterodimer binds to fatty acid-like ligands IEA Homo sapiens 5567 R-HSA-560472 https://reactome.org/PathwayBrowser/#/R-HSA-560472 Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) TAS Homo sapiens 5567 R-HSA-560473 https://reactome.org/PathwayBrowser/#/R-HSA-560473 Expression of ANGPTL4 TAS Homo sapiens 5567 R-HSA-560491 https://reactome.org/PathwayBrowser/#/R-HSA-560491 Expression of CEBPA IEA Homo sapiens 5567 R-HSA-560493 https://reactome.org/PathwayBrowser/#/R-HSA-560493 Expression of Perilipin (PLIN) TAS Homo sapiens 5567 R-HSA-560498 https://reactome.org/PathwayBrowser/#/R-HSA-560498 Expression of Lipoprotein lipase (LPL) TAS Homo sapiens 5567 R-HSA-560510 https://reactome.org/PathwayBrowser/#/R-HSA-560510 Expression of FABP4 (aP2) TAS Homo sapiens 5567 R-HSA-560517 https://reactome.org/PathwayBrowser/#/R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) TAS Homo sapiens 5567 R-HSA-8944099 https://reactome.org/PathwayBrowser/#/R-HSA-8944099 Activated PPARG binds PTEN gene promoter TAS Homo sapiens 5567 R-HSA-8944104 https://reactome.org/PathwayBrowser/#/R-HSA-8944104 PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN IEA Homo sapiens 5567 R-HSA-9842815 https://reactome.org/PathwayBrowser/#/R-HSA-9842815 PPARG binds ligands IEA Homo sapiens 5567 R-HSA-9843116 https://reactome.org/PathwayBrowser/#/R-HSA-9843116 PPARG2 transcription is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9843117 https://reactome.org/PathwayBrowser/#/R-HSA-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer TAS Homo sapiens 5567 R-HSA-9843118 https://reactome.org/PathwayBrowser/#/R-HSA-9843118 RXRA binds ligands TAS Homo sapiens 5567 R-HSA-9843119 https://reactome.org/PathwayBrowser/#/R-HSA-9843119 MLL4-ASCOM,(MLL3-ASCOM) complex is recruited to ligand- and coactivator-bound PPARG:RXRA heterodimer IEA Homo sapiens 5567 R-HSA-9843120 https://reactome.org/PathwayBrowser/#/R-HSA-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer TAS Homo sapiens 5567 R-HSA-9843121 https://reactome.org/PathwayBrowser/#/R-HSA-9843121 KMT2D,(KMT2C) complex monomethylates nucleosomes at PPARG:RXRA-bound enhancers IEA Homo sapiens 5567 R-HSA-9843900 https://reactome.org/PathwayBrowser/#/R-HSA-9843900 FABP4 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9844415 https://reactome.org/PathwayBrowser/#/R-HSA-9844415 PRDM16 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 IEA Homo sapiens 5567 R-HSA-9844440 https://reactome.org/PathwayBrowser/#/R-HSA-9844440 PPARG binds EBF2-bound gene loci IEA Homo sapiens 5567 R-HSA-9844536 https://reactome.org/PathwayBrowser/#/R-HSA-9844536 PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 5567 R-HSA-9844549 https://reactome.org/PathwayBrowser/#/R-HSA-9844549 UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 5567 R-HSA-9844600 https://reactome.org/PathwayBrowser/#/R-HSA-9844600 CIDEA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD IEA Homo sapiens 5567 R-HSA-9844822 https://reactome.org/PathwayBrowser/#/R-HSA-9844822 PPARGC1A gene expression is stimulated by EBF2 IEA Homo sapiens 5567 R-HSA-9851530 https://reactome.org/PathwayBrowser/#/R-HSA-9851530 CD36 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9851534 https://reactome.org/PathwayBrowser/#/R-HSA-9851534 CIDEC gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9851539 https://reactome.org/PathwayBrowser/#/R-HSA-9851539 SCD gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9854128 https://reactome.org/PathwayBrowser/#/R-HSA-9854128 ACSS3 gene expression is stimulated by PPARG2:RXRA:MLL4(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9854130 https://reactome.org/PathwayBrowser/#/R-HSA-9854130 THRSP gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9854141 https://reactome.org/PathwayBrowser/#/R-HSA-9854141 GPAM gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9854142 https://reactome.org/PathwayBrowser/#/R-HSA-9854142 ELOVL5 gene expression is stimulated by PPARG2:RXRA:MLL4(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9854146 https://reactome.org/PathwayBrowser/#/R-HSA-9854146 SCD5 gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9856211 https://reactome.org/PathwayBrowser/#/R-HSA-9856211 ADIPOQ gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9856486 https://reactome.org/PathwayBrowser/#/R-HSA-9856486 CEBPA gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859005 https://reactome.org/PathwayBrowser/#/R-HSA-9859005 PEX11A gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859007 https://reactome.org/PathwayBrowser/#/R-HSA-9859007 PLIN1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859082 https://reactome.org/PathwayBrowser/#/R-HSA-9859082 PNPLA2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859084 https://reactome.org/PathwayBrowser/#/R-HSA-9859084 AGPAT2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859119 https://reactome.org/PathwayBrowser/#/R-HSA-9859119 PDK4 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859121 https://reactome.org/PathwayBrowser/#/R-HSA-9859121 ANGPTL4 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859182 https://reactome.org/PathwayBrowser/#/R-HSA-9859182 LPL gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859188 https://reactome.org/PathwayBrowser/#/R-HSA-9859188 ACSL1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859196 https://reactome.org/PathwayBrowser/#/R-HSA-9859196 PLIN2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859206 https://reactome.org/PathwayBrowser/#/R-HSA-9859206 PLIN4 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859223 https://reactome.org/PathwayBrowser/#/R-HSA-9859223 LIPE gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859273 https://reactome.org/PathwayBrowser/#/R-HSA-9859273 MGLL gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859291 https://reactome.org/PathwayBrowser/#/R-HSA-9859291 DGAT2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-HSA-9859334 https://reactome.org/PathwayBrowser/#/R-HSA-9859334 LPIN1 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex IEA Homo sapiens 5567 R-MMU-556760 https://reactome.org/PathwayBrowser/#/R-MMU-556760 Pparg:Rxra heterodimer binds to fatty acids TAS Mus musculus 5567 R-MMU-9843118 https://reactome.org/PathwayBrowser/#/R-MMU-9843118 RXRA binds ligands IEA Mus musculus 5567 R-MMU-9843904 https://reactome.org/PathwayBrowser/#/R-MMU-9843904 Fabp4 gene transcription is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9844541 https://reactome.org/PathwayBrowser/#/R-MMU-9844541 Ppara gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 5567 R-MMU-9844554 https://reactome.org/PathwayBrowser/#/R-MMU-9844554 Ucp1 gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 5567 R-MMU-9844626 https://reactome.org/PathwayBrowser/#/R-MMU-9844626 Cidea gene expression is stimulated by Ebf2 and Pparg and repressed by Znf423 and NuRD TAS Mus musculus 5567 R-MMU-9844655 https://reactome.org/PathwayBrowser/#/R-MMU-9844655 Dio2 gene expression is stimulated by Ebf2 and repressed by Znf423 and NuRD TAS Mus musculus 5567 R-MMU-9844700 https://reactome.org/PathwayBrowser/#/R-MMU-9844700 Pparg binds Ebf2-bound gene loci TAS Mus musculus 5567 R-MMU-9844775 https://reactome.org/PathwayBrowser/#/R-MMU-9844775 Prdm16 gene expression is stimulated by Ebf2 and Pparg and inhibited by Znf423 TAS Mus musculus 5567 R-MMU-9844841 https://reactome.org/PathwayBrowser/#/R-MMU-9844841 Ppargc1a gene expression is positively regulated by Ebf2 and Pparg TAS Mus musculus 5567 R-MMU-9856206 https://reactome.org/PathwayBrowser/#/R-MMU-9856206 Mll4-ASCOM,(Mll3-ASCOM) complex is recruited to activated Pparg:Rxra complex at target adipogenic gene loci TAS Mus musculus 5567 R-MMU-9856214 https://reactome.org/PathwayBrowser/#/R-MMU-9856214 Adipoq gene expression is stimulated by Pparg and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9856368 https://reactome.org/PathwayBrowser/#/R-MMU-9856368 Kmt2d,(Kmt2c) monomethylates nucleosomes at Pparg:Rxra-bound enhancers TAS Mus musculus 5567 R-MMU-9906987 https://reactome.org/PathwayBrowser/#/R-MMU-9906987 Acsl1 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9906989 https://reactome.org/PathwayBrowser/#/R-MMU-9906989 Acss3 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9906994 https://reactome.org/PathwayBrowser/#/R-MMU-9906994 Agpat2 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907162 https://reactome.org/PathwayBrowser/#/R-MMU-9907162 Angptl4 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907166 https://reactome.org/PathwayBrowser/#/R-MMU-9907166 Cd36 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907178 https://reactome.org/PathwayBrowser/#/R-MMU-9907178 Cidec gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907190 https://reactome.org/PathwayBrowser/#/R-MMU-9907190 Dgat2 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907194 https://reactome.org/PathwayBrowser/#/R-MMU-9907194 Elovl5 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907201 https://reactome.org/PathwayBrowser/#/R-MMU-9907201 Gpam gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907236 https://reactome.org/PathwayBrowser/#/R-MMU-9907236 Pdk4 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907261 https://reactome.org/PathwayBrowser/#/R-MMU-9907261 Pex11a gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907267 https://reactome.org/PathwayBrowser/#/R-MMU-9907267 Plin1 gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907270 https://reactome.org/PathwayBrowser/#/R-MMU-9907270 Plin2 gene expression is positively regulated by Pparg:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907291 https://reactome.org/PathwayBrowser/#/R-MMU-9907291 Scd1 gene expression is stimulated by p-Y78,Y102-Pparg2:Rxra and Mll4,(Mll3) TAS Mus musculus 5567 R-MMU-9907296 https://reactome.org/PathwayBrowser/#/R-MMU-9907296 Scd4 gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-MMU-9907303 https://reactome.org/PathwayBrowser/#/R-MMU-9907303 Thrsp gene expression is stimulated by Pparg2:Rxra and Mll4,(Mll3) complex TAS Mus musculus 5567 R-RNO-9843117 https://reactome.org/PathwayBrowser/#/R-RNO-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Rattus norvegicus 5567 R-RNO-9843118 https://reactome.org/PathwayBrowser/#/R-RNO-9843118 RXRA binds ligands IEA Rattus norvegicus 5567 R-RNO-9843120 https://reactome.org/PathwayBrowser/#/R-RNO-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Rattus norvegicus 5567 R-SSC-9843117 https://reactome.org/PathwayBrowser/#/R-SSC-9843117 Corepressors are released from liganded PPARG:RXRA heterodimer IEA Sus scrofa 5567 R-SSC-9843118 https://reactome.org/PathwayBrowser/#/R-SSC-9843118 RXRA binds ligands IEA Sus scrofa 5567 R-SSC-9843120 https://reactome.org/PathwayBrowser/#/R-SSC-9843120 Coactivators are recruited to liganded PPARG:RXRA heterodimer IEA Sus scrofa 5567 R-XTR-9843118 https://reactome.org/PathwayBrowser/#/R-XTR-9843118 RXRA binds ligands IEA Xenopus tropicalis 5585 R-BTA-9718394 https://reactome.org/PathwayBrowser/#/R-BTA-9718394 GNRHR binds GNRHR peptide antagonists IEA Bos taurus 5585 R-CEL-9718394 https://reactome.org/PathwayBrowser/#/R-CEL-9718394 GNRHR binds GNRHR peptide antagonists IEA Caenorhabditis elegans 5585 R-CFA-9718394 https://reactome.org/PathwayBrowser/#/R-CFA-9718394 GNRHR binds GNRHR peptide antagonists IEA Canis familiaris 5585 R-DME-9718394 https://reactome.org/PathwayBrowser/#/R-DME-9718394 GNRHR binds GNRHR peptide antagonists IEA Drosophila melanogaster 5585 R-DRE-9718394 https://reactome.org/PathwayBrowser/#/R-DRE-9718394 GNRHR binds GNRHR peptide antagonists IEA Danio rerio 5585 R-GGA-9718394 https://reactome.org/PathwayBrowser/#/R-GGA-9718394 GNRHR binds GNRHR peptide antagonists IEA Gallus gallus 5585 R-HSA-9718394 https://reactome.org/PathwayBrowser/#/R-HSA-9718394 GNRHR binds GNRHR peptide antagonists TAS Homo sapiens 5585 R-MMU-9718394 https://reactome.org/PathwayBrowser/#/R-MMU-9718394 GNRHR binds GNRHR peptide antagonists IEA Mus musculus 5585 R-RNO-9718394 https://reactome.org/PathwayBrowser/#/R-RNO-9718394 GNRHR binds GNRHR peptide antagonists IEA Rattus norvegicus 5585 R-SSC-9718394 https://reactome.org/PathwayBrowser/#/R-SSC-9718394 GNRHR binds GNRHR peptide antagonists IEA Sus scrofa 5585 R-XTR-9718394 https://reactome.org/PathwayBrowser/#/R-XTR-9718394 GNRHR binds GNRHR peptide antagonists IEA Xenopus tropicalis 5586 R-BTA-9718379 https://reactome.org/PathwayBrowser/#/R-BTA-9718379 GNRHR binds chemical antagonists IEA Bos taurus 5586 R-CEL-9718379 https://reactome.org/PathwayBrowser/#/R-CEL-9718379 GNRHR binds chemical antagonists IEA Caenorhabditis elegans 5586 R-CFA-9718379 https://reactome.org/PathwayBrowser/#/R-CFA-9718379 GNRHR binds chemical antagonists IEA Canis familiaris 5586 R-DME-9718379 https://reactome.org/PathwayBrowser/#/R-DME-9718379 GNRHR binds chemical antagonists IEA Drosophila melanogaster 5586 R-DRE-9718379 https://reactome.org/PathwayBrowser/#/R-DRE-9718379 GNRHR binds chemical antagonists IEA Danio rerio 5586 R-GGA-9718379 https://reactome.org/PathwayBrowser/#/R-GGA-9718379 GNRHR binds chemical antagonists IEA Gallus gallus 5586 R-HSA-9718379 https://reactome.org/PathwayBrowser/#/R-HSA-9718379 GNRHR binds chemical antagonists TAS Homo sapiens 5586 R-MMU-9718379 https://reactome.org/PathwayBrowser/#/R-MMU-9718379 GNRHR binds chemical antagonists IEA Mus musculus 5586 R-RNO-9718379 https://reactome.org/PathwayBrowser/#/R-RNO-9718379 GNRHR binds chemical antagonists IEA Rattus norvegicus 5586 R-SSC-9718379 https://reactome.org/PathwayBrowser/#/R-SSC-9718379 GNRHR binds chemical antagonists IEA Sus scrofa 5586 R-XTR-9718379 https://reactome.org/PathwayBrowser/#/R-XTR-9718379 GNRHR binds chemical antagonists IEA Xenopus tropicalis 56 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 56 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 56 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 56 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 56 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 56 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 56 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 56 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 56 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 56 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 56 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 56 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 56 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 56 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 56 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 56 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 56 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 56 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 56 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 56 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 564 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 564 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 564 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 564 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 564 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 564 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 564 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 564 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 564 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 564 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 564 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 564 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 564 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 564 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 564 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 564 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 564 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 564 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 564 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 564 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 564 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 564 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 564 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 564 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 564 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 564 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 564 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 564 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 564 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 564 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 564 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 564 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 564 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 564 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 564 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 564 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 564 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 5656 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5656 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5656 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5656 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5656 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5656 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5656 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5656 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5656 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5656 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5656 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5656 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5656 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5656 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5656 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5656 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5656 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5656 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5656 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5656 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5656 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5656 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5656 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5656 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5656 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 5656 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5656 R-HSA-9669863 https://reactome.org/PathwayBrowser/#/R-HSA-9669863 Masitinib-resistant KIT mutants do not bind masitinib TAS Homo sapiens 5656 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5656 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5656 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5656 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5656 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5656 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5656 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5656 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5656 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5656 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5656 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5656 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5656 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5656 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5656 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5656 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5656 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5656 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5656 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5657 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5657 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5657 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5657 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 5657 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 5657 R-HSA-9702997 https://reactome.org/PathwayBrowser/#/R-HSA-9702997 linafinib-resistant FLT3 mutants don't bind linifanib TAS Homo sapiens 5657 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5657 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5658 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5658 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5658 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5658 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 5658 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 5658 R-HSA-9702618 https://reactome.org/PathwayBrowser/#/R-HSA-9702618 quizartinib-resistant FLT3 mutants don't bind quizartinib TAS Homo sapiens 5658 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5658 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5659 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5659 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5659 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5659 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5659 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5659 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5659 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5659 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5659 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5659 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5659 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5659 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5659 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5659 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5659 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5659 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5659 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5659 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5659 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5659 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5659 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5659 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5659 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5659 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5659 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5659 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5659 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5659 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5659 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5659 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5659 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5659 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5659 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5659 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5659 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5659 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5659 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5659 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5659 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5659 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5659 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5659 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5659 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5659 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5664 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 5664 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 5665 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 5665 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 5665 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 5665 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 5665 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 5665 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 5665 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 5665 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 5665 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 5665 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 5665 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 5665 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 5665 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 5665 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 5665 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 5665 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 5665 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 5665 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 5667 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 5667 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 5667 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 5667 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 5667 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 5667 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 5667 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 5667 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 5667 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 5667 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 5667 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 5667 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 5667 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 5667 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 5667 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 5667 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 5667 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 5667 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 5667 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 5667 R-HSA-9665311 https://reactome.org/PathwayBrowser/#/R-HSA-9665311 ERBB2 T798M does not bind afatinib TAS Homo sapiens 5667 R-HSA-9665389 https://reactome.org/PathwayBrowser/#/R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate TAS Homo sapiens 5667 R-HSA-9665412 https://reactome.org/PathwayBrowser/#/R-HSA-9665412 ERBB2 ECD mutants bind TKIs TAS Homo sapiens 5667 R-HSA-9665702 https://reactome.org/PathwayBrowser/#/R-HSA-9665702 ERBB2 TMD/JMD mutants bind TKIs TAS Homo sapiens 5667 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 5667 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 5667 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 5667 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 5667 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 5667 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 5671 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 5672 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5672 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5672 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5672 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 5672 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 5672 R-HSA-9702593 https://reactome.org/PathwayBrowser/#/R-HSA-9702593 lestaurtinib-resistant FLT3 mutants don't bind lestaurtinib TAS Homo sapiens 5672 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5672 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5675 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 5675 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 5675 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 5675 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 5675 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 5675 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 5675 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 5675 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 5675 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 5675 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 5675 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 5675 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 5675 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 5675 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 5675 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 5675 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 5675 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 5675 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 5675 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 5675 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 5675 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 5675 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 5675 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 5675 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 5675 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 5676 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 5676 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 5676 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 5676 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 5676 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 5676 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 5676 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 5676 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 5676 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 5676 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 5676 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 5676 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 5676 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 5676 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 5676 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 5676 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 5676 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 5676 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 5677 R-BTA-451895 https://reactome.org/PathwayBrowser/#/R-BTA-451895 IL2RG binds JAK3 IEA Bos taurus 5677 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 5677 R-BTA-909724 https://reactome.org/PathwayBrowser/#/R-BTA-909724 Recruitment of IFNAR1 IEA Bos taurus 5677 R-BTA-9678561 https://reactome.org/PathwayBrowser/#/R-BTA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Bos taurus 5677 R-BTA-9678737 https://reactome.org/PathwayBrowser/#/R-BTA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Bos taurus 5677 R-BTA-9678935 https://reactome.org/PathwayBrowser/#/R-BTA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Bos taurus 5677 R-BTA-9679028 https://reactome.org/PathwayBrowser/#/R-BTA-9679028 JAK3 binds JAK3 inhibitors IEA Bos taurus 5677 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 5677 R-CFA-909724 https://reactome.org/PathwayBrowser/#/R-CFA-909724 Recruitment of IFNAR1 IEA Canis familiaris 5677 R-CFA-9678561 https://reactome.org/PathwayBrowser/#/R-CFA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Canis familiaris 5677 R-CFA-9678737 https://reactome.org/PathwayBrowser/#/R-CFA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Canis familiaris 5677 R-CFA-9678935 https://reactome.org/PathwayBrowser/#/R-CFA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Canis familiaris 5677 R-CFA-9679028 https://reactome.org/PathwayBrowser/#/R-CFA-9679028 JAK3 binds JAK3 inhibitors IEA Canis familiaris 5677 R-DME-9679028 https://reactome.org/PathwayBrowser/#/R-DME-9679028 JAK3 binds JAK3 inhibitors IEA Drosophila melanogaster 5677 R-DRE-9678561 https://reactome.org/PathwayBrowser/#/R-DRE-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Danio rerio 5677 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 5677 R-GGA-909724 https://reactome.org/PathwayBrowser/#/R-GGA-909724 Recruitment of IFNAR1 IEA Gallus gallus 5677 R-GGA-9678561 https://reactome.org/PathwayBrowser/#/R-GGA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Gallus gallus 5677 R-GGA-9678737 https://reactome.org/PathwayBrowser/#/R-GGA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Gallus gallus 5677 R-GGA-9678935 https://reactome.org/PathwayBrowser/#/R-GGA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Gallus gallus 5677 R-HSA-451895 https://reactome.org/PathwayBrowser/#/R-HSA-451895 IL2RG binds JAK3 TAS Homo sapiens 5677 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 5677 R-HSA-909724 https://reactome.org/PathwayBrowser/#/R-HSA-909724 Recruitment of IFNAR1 TAS Homo sapiens 5677 R-HSA-9678561 https://reactome.org/PathwayBrowser/#/R-HSA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors TAS Homo sapiens 5677 R-HSA-9678737 https://reactome.org/PathwayBrowser/#/R-HSA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors TAS Homo sapiens 5677 R-HSA-9678935 https://reactome.org/PathwayBrowser/#/R-HSA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors TAS Homo sapiens 5677 R-HSA-9679028 https://reactome.org/PathwayBrowser/#/R-HSA-9679028 JAK3 binds JAK3 inhibitors TAS Homo sapiens 5677 R-MMU-451895 https://reactome.org/PathwayBrowser/#/R-MMU-451895 IL2RG binds JAK3 IEA Mus musculus 5677 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 5677 R-MMU-909724 https://reactome.org/PathwayBrowser/#/R-MMU-909724 Recruitment of IFNAR1 IEA Mus musculus 5677 R-MMU-9678561 https://reactome.org/PathwayBrowser/#/R-MMU-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Mus musculus 5677 R-MMU-9678737 https://reactome.org/PathwayBrowser/#/R-MMU-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Mus musculus 5677 R-MMU-9678935 https://reactome.org/PathwayBrowser/#/R-MMU-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Mus musculus 5677 R-MMU-9679028 https://reactome.org/PathwayBrowser/#/R-MMU-9679028 JAK3 binds JAK3 inhibitors IEA Mus musculus 5677 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 5677 R-RNO-909724 https://reactome.org/PathwayBrowser/#/R-RNO-909724 Recruitment of IFNAR1 IEA Rattus norvegicus 5677 R-RNO-9678561 https://reactome.org/PathwayBrowser/#/R-RNO-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Rattus norvegicus 5677 R-RNO-9678737 https://reactome.org/PathwayBrowser/#/R-RNO-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Rattus norvegicus 5677 R-RNO-9678935 https://reactome.org/PathwayBrowser/#/R-RNO-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Rattus norvegicus 5677 R-RNO-9679028 https://reactome.org/PathwayBrowser/#/R-RNO-9679028 JAK3 binds JAK3 inhibitors IEA Rattus norvegicus 5677 R-SSC-451895 https://reactome.org/PathwayBrowser/#/R-SSC-451895 IL2RG binds JAK3 IEA Sus scrofa 5677 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 5677 R-SSC-909724 https://reactome.org/PathwayBrowser/#/R-SSC-909724 Recruitment of IFNAR1 IEA Sus scrofa 5677 R-SSC-9678561 https://reactome.org/PathwayBrowser/#/R-SSC-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Sus scrofa 5677 R-SSC-9678737 https://reactome.org/PathwayBrowser/#/R-SSC-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Sus scrofa 5677 R-SSC-9678935 https://reactome.org/PathwayBrowser/#/R-SSC-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Sus scrofa 5677 R-SSC-9679028 https://reactome.org/PathwayBrowser/#/R-SSC-9679028 JAK3 binds JAK3 inhibitors IEA Sus scrofa 5677 R-XTR-909724 https://reactome.org/PathwayBrowser/#/R-XTR-909724 Recruitment of IFNAR1 IEA Xenopus tropicalis 5677 R-XTR-9678561 https://reactome.org/PathwayBrowser/#/R-XTR-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 5677 R-XTR-9678737 https://reactome.org/PathwayBrowser/#/R-XTR-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Xenopus tropicalis 5677 R-XTR-9678935 https://reactome.org/PathwayBrowser/#/R-XTR-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 5677 R-XTR-9679028 https://reactome.org/PathwayBrowser/#/R-XTR-9679028 JAK3 binds JAK3 inhibitors IEA Xenopus tropicalis 5678 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5678 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5678 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5678 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5678 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5678 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5678 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5678 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5678 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5678 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5678 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5678 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5678 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5678 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5678 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5678 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5678 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5678 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5678 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5678 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5678 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5678 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5678 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5678 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5678 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5678 R-HSA-9669855 https://reactome.org/PathwayBrowser/#/R-HSA-9669855 Dasatinib-resistant KIT mutants do not bind dasatinib TAS Homo sapiens 5678 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5678 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5678 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5678 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5678 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5678 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5678 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5678 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5678 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5678 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5678 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5678 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5678 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5678 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5678 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5678 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5678 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5678 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5678 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5679 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 5679 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 5679 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 5679 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 5679 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 5679 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 5679 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 5679 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 5679 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 5679 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 5679 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 5679 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 5679 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 5679 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 5679 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 5679 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 5679 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 5679 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 5680 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 5680 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 5680 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 5680 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 5680 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 5680 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 5680 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 5680 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 5680 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 5680 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 5680 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 5680 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 5680 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 5680 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 5680 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 5680 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 5680 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 5680 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 5682 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 5686 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 5686 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 5686 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 5686 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 5686 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 5686 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 5686 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 5686 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 5686 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 5686 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 5686 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 5686 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 5686 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 5686 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 5686 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 5686 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 5686 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 5686 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 5686 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 5686 R-HSA-9665286 https://reactome.org/PathwayBrowser/#/R-HSA-9665286 Resistant ERBB2 KD mutants do not bind neratinib TAS Homo sapiens 5686 R-HSA-9665389 https://reactome.org/PathwayBrowser/#/R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate TAS Homo sapiens 5686 R-HSA-9665412 https://reactome.org/PathwayBrowser/#/R-HSA-9665412 ERBB2 ECD mutants bind TKIs TAS Homo sapiens 5686 R-HSA-9665702 https://reactome.org/PathwayBrowser/#/R-HSA-9665702 ERBB2 TMD/JMD mutants bind TKIs TAS Homo sapiens 5686 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 5686 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 5686 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 5686 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 5686 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 5686 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 5687 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 5687 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5687 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5687 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 5687 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5687 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5687 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5687 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5687 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5687 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 5687 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5687 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5687 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 5687 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5687 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5687 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 5687 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 5687 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5687 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5687 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5687 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5687 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5687 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5687 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5687 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 5687 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5687 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5687 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 5687 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5687 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5687 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 5687 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5687 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5687 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 5687 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5687 R-HSA-9669859 https://reactome.org/PathwayBrowser/#/R-HSA-9669859 Imatinib-resistant KIT mutants do not bind imatinib TAS Homo sapiens 5687 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5687 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5687 R-HSA-9674397 https://reactome.org/PathwayBrowser/#/R-HSA-9674397 Imatinib-resistant PDGFR mutants don't bind imatinib TAS Homo sapiens 5687 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5687 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 5687 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5687 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5687 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 5687 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5687 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5687 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 5687 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 5687 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 5687 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5687 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5687 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 5687 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5687 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5687 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 5687 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 5687 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 5687 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5687 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5687 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 5687 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5687 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5687 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5687 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5687 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5687 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5688 R-BTA-451895 https://reactome.org/PathwayBrowser/#/R-BTA-451895 IL2RG binds JAK3 IEA Bos taurus 5688 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 5688 R-BTA-909724 https://reactome.org/PathwayBrowser/#/R-BTA-909724 Recruitment of IFNAR1 IEA Bos taurus 5688 R-BTA-9678561 https://reactome.org/PathwayBrowser/#/R-BTA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Bos taurus 5688 R-BTA-9678737 https://reactome.org/PathwayBrowser/#/R-BTA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Bos taurus 5688 R-BTA-9678935 https://reactome.org/PathwayBrowser/#/R-BTA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Bos taurus 5688 R-BTA-9679028 https://reactome.org/PathwayBrowser/#/R-BTA-9679028 JAK3 binds JAK3 inhibitors IEA Bos taurus 5688 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 5688 R-CFA-909724 https://reactome.org/PathwayBrowser/#/R-CFA-909724 Recruitment of IFNAR1 IEA Canis familiaris 5688 R-CFA-9678561 https://reactome.org/PathwayBrowser/#/R-CFA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Canis familiaris 5688 R-CFA-9678737 https://reactome.org/PathwayBrowser/#/R-CFA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Canis familiaris 5688 R-CFA-9678935 https://reactome.org/PathwayBrowser/#/R-CFA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Canis familiaris 5688 R-CFA-9679028 https://reactome.org/PathwayBrowser/#/R-CFA-9679028 JAK3 binds JAK3 inhibitors IEA Canis familiaris 5688 R-DME-9679028 https://reactome.org/PathwayBrowser/#/R-DME-9679028 JAK3 binds JAK3 inhibitors IEA Drosophila melanogaster 5688 R-DRE-9678561 https://reactome.org/PathwayBrowser/#/R-DRE-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Danio rerio 5688 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 5688 R-GGA-909724 https://reactome.org/PathwayBrowser/#/R-GGA-909724 Recruitment of IFNAR1 IEA Gallus gallus 5688 R-GGA-9678561 https://reactome.org/PathwayBrowser/#/R-GGA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Gallus gallus 5688 R-GGA-9678737 https://reactome.org/PathwayBrowser/#/R-GGA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Gallus gallus 5688 R-GGA-9678935 https://reactome.org/PathwayBrowser/#/R-GGA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Gallus gallus 5688 R-HSA-451895 https://reactome.org/PathwayBrowser/#/R-HSA-451895 IL2RG binds JAK3 TAS Homo sapiens 5688 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 5688 R-HSA-909724 https://reactome.org/PathwayBrowser/#/R-HSA-909724 Recruitment of IFNAR1 TAS Homo sapiens 5688 R-HSA-9678561 https://reactome.org/PathwayBrowser/#/R-HSA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors TAS Homo sapiens 5688 R-HSA-9678737 https://reactome.org/PathwayBrowser/#/R-HSA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors TAS Homo sapiens 5688 R-HSA-9678935 https://reactome.org/PathwayBrowser/#/R-HSA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors TAS Homo sapiens 5688 R-HSA-9679028 https://reactome.org/PathwayBrowser/#/R-HSA-9679028 JAK3 binds JAK3 inhibitors TAS Homo sapiens 5688 R-MMU-451895 https://reactome.org/PathwayBrowser/#/R-MMU-451895 IL2RG binds JAK3 IEA Mus musculus 5688 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 5688 R-MMU-909724 https://reactome.org/PathwayBrowser/#/R-MMU-909724 Recruitment of IFNAR1 IEA Mus musculus 5688 R-MMU-9678561 https://reactome.org/PathwayBrowser/#/R-MMU-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Mus musculus 5688 R-MMU-9678737 https://reactome.org/PathwayBrowser/#/R-MMU-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Mus musculus 5688 R-MMU-9678935 https://reactome.org/PathwayBrowser/#/R-MMU-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Mus musculus 5688 R-MMU-9679028 https://reactome.org/PathwayBrowser/#/R-MMU-9679028 JAK3 binds JAK3 inhibitors IEA Mus musculus 5688 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 5688 R-RNO-909724 https://reactome.org/PathwayBrowser/#/R-RNO-909724 Recruitment of IFNAR1 IEA Rattus norvegicus 5688 R-RNO-9678561 https://reactome.org/PathwayBrowser/#/R-RNO-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Rattus norvegicus 5688 R-RNO-9678737 https://reactome.org/PathwayBrowser/#/R-RNO-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Rattus norvegicus 5688 R-RNO-9678935 https://reactome.org/PathwayBrowser/#/R-RNO-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Rattus norvegicus 5688 R-RNO-9679028 https://reactome.org/PathwayBrowser/#/R-RNO-9679028 JAK3 binds JAK3 inhibitors IEA Rattus norvegicus 5688 R-SSC-451895 https://reactome.org/PathwayBrowser/#/R-SSC-451895 IL2RG binds JAK3 IEA Sus scrofa 5688 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 5688 R-SSC-909724 https://reactome.org/PathwayBrowser/#/R-SSC-909724 Recruitment of IFNAR1 IEA Sus scrofa 5688 R-SSC-9678561 https://reactome.org/PathwayBrowser/#/R-SSC-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Sus scrofa 5688 R-SSC-9678737 https://reactome.org/PathwayBrowser/#/R-SSC-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Sus scrofa 5688 R-SSC-9678935 https://reactome.org/PathwayBrowser/#/R-SSC-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Sus scrofa 5688 R-SSC-9679028 https://reactome.org/PathwayBrowser/#/R-SSC-9679028 JAK3 binds JAK3 inhibitors IEA Sus scrofa 5688 R-XTR-909724 https://reactome.org/PathwayBrowser/#/R-XTR-909724 Recruitment of IFNAR1 IEA Xenopus tropicalis 5688 R-XTR-9678561 https://reactome.org/PathwayBrowser/#/R-XTR-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 5688 R-XTR-9678737 https://reactome.org/PathwayBrowser/#/R-XTR-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Xenopus tropicalis 5688 R-XTR-9678935 https://reactome.org/PathwayBrowser/#/R-XTR-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 5688 R-XTR-9679028 https://reactome.org/PathwayBrowser/#/R-XTR-9679028 JAK3 binds JAK3 inhibitors IEA Xenopus tropicalis 5691 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5691 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5691 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5691 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 5691 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 5691 R-HSA-9702570 https://reactome.org/PathwayBrowser/#/R-HSA-9702570 KW2449-resistant FLT3 mutants don't bind KW2449 TAS Homo sapiens 5691 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5691 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5692 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 5692 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 5692 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 5692 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 5692 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 5692 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 5692 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 5692 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 5692 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 5692 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 5692 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 5692 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 5692 R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 5692 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 5692 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 5692 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 5692 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 5692 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 5692 R-HSA-9665284 https://reactome.org/PathwayBrowser/#/R-HSA-9665284 Resistant ERBB2 KD mutants do not bind lapatinib TAS Homo sapiens 5692 R-HSA-9665389 https://reactome.org/PathwayBrowser/#/R-HSA-9665389 Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate TAS Homo sapiens 5692 R-HSA-9665412 https://reactome.org/PathwayBrowser/#/R-HSA-9665412 ERBB2 ECD mutants bind TKIs TAS Homo sapiens 5692 R-HSA-9665702 https://reactome.org/PathwayBrowser/#/R-HSA-9665702 ERBB2 TMD/JMD mutants bind TKIs TAS Homo sapiens 5692 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 5692 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 5692 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 5692 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 5692 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 5692 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 5695 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5695 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5695 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5695 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 5695 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 5695 R-HSA-9702638 https://reactome.org/PathwayBrowser/#/R-HSA-9702638 tandutinib-resistant FLT3 mutants don't bind tandutinib TAS Homo sapiens 5695 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5695 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5697 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5697 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5697 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5697 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5697 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5697 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5697 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5697 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5697 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5697 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5697 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5697 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5697 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5697 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5697 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5697 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5697 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5697 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5697 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5697 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5697 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5697 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5697 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5697 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5697 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5697 R-HSA-9669868 https://reactome.org/PathwayBrowser/#/R-HSA-9669868 Nilotinib-resistant KIT mutants do not bind nilotinib TAS Homo sapiens 5697 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5697 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5697 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5697 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5697 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5697 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5697 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5697 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5697 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5697 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5697 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5697 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5697 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5697 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5697 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5697 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5697 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5697 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5697 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5698 R-BTA-389083 https://reactome.org/PathwayBrowser/#/R-BTA-389083 Autophosphorylation of PDGF alpha receptors IEA Bos taurus 5698 R-BTA-5213464 https://reactome.org/PathwayBrowser/#/R-BTA-5213464 RIPK1 is phosphorylated IEA Bos taurus 5698 R-BTA-5213466 https://reactome.org/PathwayBrowser/#/R-BTA-5213466 RIPK3 is phosphorylated IEA Bos taurus 5698 R-BTA-9674093 https://reactome.org/PathwayBrowser/#/R-BTA-9674093 PDGFRs bind type I TKI IEA Bos taurus 5698 R-BTA-9693978 https://reactome.org/PathwayBrowser/#/R-BTA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Bos taurus 5698 R-CEL-389083 https://reactome.org/PathwayBrowser/#/R-CEL-389083 Autophosphorylation of PDGF alpha receptors IEA Caenorhabditis elegans 5698 R-CEL-9674093 https://reactome.org/PathwayBrowser/#/R-CEL-9674093 PDGFRs bind type I TKI IEA Caenorhabditis elegans 5698 R-CFA-389083 https://reactome.org/PathwayBrowser/#/R-CFA-389083 Autophosphorylation of PDGF alpha receptors IEA Canis familiaris 5698 R-CFA-5213464 https://reactome.org/PathwayBrowser/#/R-CFA-5213464 RIPK1 is phosphorylated IEA Canis familiaris 5698 R-CFA-5213466 https://reactome.org/PathwayBrowser/#/R-CFA-5213466 RIPK3 is phosphorylated IEA Canis familiaris 5698 R-CFA-9674093 https://reactome.org/PathwayBrowser/#/R-CFA-9674093 PDGFRs bind type I TKI IEA Canis familiaris 5698 R-CFA-9693978 https://reactome.org/PathwayBrowser/#/R-CFA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Canis familiaris 5698 R-DME-389083 https://reactome.org/PathwayBrowser/#/R-DME-389083 Autophosphorylation of PDGF alpha receptors IEA Drosophila melanogaster 5698 R-DME-9674093 https://reactome.org/PathwayBrowser/#/R-DME-9674093 PDGFRs bind type I TKI IEA Drosophila melanogaster 5698 R-DRE-389083 https://reactome.org/PathwayBrowser/#/R-DRE-389083 Autophosphorylation of PDGF alpha receptors IEA Danio rerio 5698 R-DRE-9674093 https://reactome.org/PathwayBrowser/#/R-DRE-9674093 PDGFRs bind type I TKI IEA Danio rerio 5698 R-GGA-389083 https://reactome.org/PathwayBrowser/#/R-GGA-389083 Autophosphorylation of PDGF alpha receptors IEA Gallus gallus 5698 R-GGA-9674093 https://reactome.org/PathwayBrowser/#/R-GGA-9674093 PDGFRs bind type I TKI IEA Gallus gallus 5698 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 5698 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 5698 R-HSA-389083 https://reactome.org/PathwayBrowser/#/R-HSA-389083 Autophosphorylation of PDGF alpha receptors TAS Homo sapiens 5698 R-HSA-5213464 https://reactome.org/PathwayBrowser/#/R-HSA-5213464 RIPK1 is phosphorylated TAS Homo sapiens 5698 R-HSA-5213466 https://reactome.org/PathwayBrowser/#/R-HSA-5213466 RIPK3 is phosphorylated TAS Homo sapiens 5698 R-HSA-9674093 https://reactome.org/PathwayBrowser/#/R-HSA-9674093 PDGFRs bind type I TKI TAS Homo sapiens 5698 R-HSA-9674427 https://reactome.org/PathwayBrowser/#/R-HSA-9674427 PDGFR mutants bind type I TKIs TAS Homo sapiens 5698 R-HSA-9693978 https://reactome.org/PathwayBrowser/#/R-HSA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 TAS Homo sapiens 5698 R-MMU-389083 https://reactome.org/PathwayBrowser/#/R-MMU-389083 Autophosphorylation of PDGF alpha receptors IEA Mus musculus 5698 R-MMU-5213464 https://reactome.org/PathwayBrowser/#/R-MMU-5213464 RIPK1 is phosphorylated IEA Mus musculus 5698 R-MMU-5213466 https://reactome.org/PathwayBrowser/#/R-MMU-5213466 RIPK3 is phosphorylated IEA Mus musculus 5698 R-MMU-9674093 https://reactome.org/PathwayBrowser/#/R-MMU-9674093 PDGFRs bind type I TKI IEA Mus musculus 5698 R-MMU-9693978 https://reactome.org/PathwayBrowser/#/R-MMU-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Mus musculus 5698 R-RNO-389083 https://reactome.org/PathwayBrowser/#/R-RNO-389083 Autophosphorylation of PDGF alpha receptors IEA Rattus norvegicus 5698 R-RNO-5213464 https://reactome.org/PathwayBrowser/#/R-RNO-5213464 RIPK1 is phosphorylated IEA Rattus norvegicus 5698 R-RNO-5213466 https://reactome.org/PathwayBrowser/#/R-RNO-5213466 RIPK3 is phosphorylated IEA Rattus norvegicus 5698 R-RNO-9674093 https://reactome.org/PathwayBrowser/#/R-RNO-9674093 PDGFRs bind type I TKI IEA Rattus norvegicus 5698 R-RNO-9693978 https://reactome.org/PathwayBrowser/#/R-RNO-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Rattus norvegicus 5698 R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa 5698 R-SSC-5213464 https://reactome.org/PathwayBrowser/#/R-SSC-5213464 RIPK1 is phosphorylated IEA Sus scrofa 5698 R-SSC-5213466 https://reactome.org/PathwayBrowser/#/R-SSC-5213466 RIPK3 is phosphorylated IEA Sus scrofa 5698 R-SSC-9674093 https://reactome.org/PathwayBrowser/#/R-SSC-9674093 PDGFRs bind type I TKI IEA Sus scrofa 5698 R-SSC-9693978 https://reactome.org/PathwayBrowser/#/R-SSC-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Sus scrofa 570 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 570 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 570 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 570 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 570 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 570 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 570 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 570 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 570 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 570 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 570 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 570 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 570 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 570 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 570 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 570 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 570 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 570 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 570 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 570 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 570 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 570 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 570 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 570 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 570 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 570 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 570 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 570 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 570 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 570 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 570 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 570 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 570 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 570 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 570 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 570 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 570 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 5700 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 5700 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 5700 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 5700 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 5700 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 5700 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 5700 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 5700 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 5700 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 5700 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 5700 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 5700 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 5700 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 5700 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 5700 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 5700 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 5700 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 5700 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 5702 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5702 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5702 R-BTA-9669893 https://reactome.org/PathwayBrowser/#/R-BTA-9669893 KIT binds type I TKIs IEA Bos taurus 5702 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5702 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5702 R-CFA-9669893 https://reactome.org/PathwayBrowser/#/R-CFA-9669893 KIT binds type I TKIs IEA Canis familiaris 5702 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5702 R-DRE-9669893 https://reactome.org/PathwayBrowser/#/R-DRE-9669893 KIT binds type I TKIs IEA Danio rerio 5702 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5702 R-GGA-9669893 https://reactome.org/PathwayBrowser/#/R-GGA-9669893 KIT binds type I TKIs IEA Gallus gallus 5702 R-HSA-1839039 https://reactome.org/PathwayBrowser/#/R-HSA-1839039 Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation TAS Homo sapiens 5702 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5702 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 5702 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5702 R-HSA-9669893 https://reactome.org/PathwayBrowser/#/R-HSA-9669893 KIT binds type I TKIs TAS Homo sapiens 5702 R-HSA-9669898 https://reactome.org/PathwayBrowser/#/R-HSA-9669898 KIT mutants bind type I TKIs TAS Homo sapiens 5702 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 5702 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 5702 R-HSA-9702601 https://reactome.org/PathwayBrowser/#/R-HSA-9702601 midostaurin-resistant FLT3 mutants don't bind midostaurin TAS Homo sapiens 5702 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5702 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5702 R-MMU-9669893 https://reactome.org/PathwayBrowser/#/R-MMU-9669893 KIT binds type I TKIs IEA Mus musculus 5702 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5702 R-RNO-9669893 https://reactome.org/PathwayBrowser/#/R-RNO-9669893 KIT binds type I TKIs IEA Rattus norvegicus 5702 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5702 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5702 R-SSC-9669893 https://reactome.org/PathwayBrowser/#/R-SSC-9669893 KIT binds type I TKIs IEA Sus scrofa 5702 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5702 R-XTR-9669893 https://reactome.org/PathwayBrowser/#/R-XTR-9669893 KIT binds type I TKIs IEA Xenopus tropicalis 5703 R-HSA-6802918 https://reactome.org/PathwayBrowser/#/R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants TAS Homo sapiens 5703 R-HSA-6802937 https://reactome.org/PathwayBrowser/#/R-HSA-6802937 Inactive BRAF mutants bind mutant RAS:GTP TAS Homo sapiens 5703 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 5703 R-HSA-6802941 https://reactome.org/PathwayBrowser/#/R-HSA-6802941 RAF is paradoxically phosphorylated downstream of kinase-inactive RAF TAS Homo sapiens 5703 R-HSA-6802942 https://reactome.org/PathwayBrowser/#/R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs TAS Homo sapiens 5703 R-HSA-6802943 https://reactome.org/PathwayBrowser/#/R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks TAS Homo sapiens 5703 R-HSA-6803234 https://reactome.org/PathwayBrowser/#/R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes TAS Homo sapiens 5703 R-HSA-8936731 https://reactome.org/PathwayBrowser/#/R-HSA-8936731 Inactive BRAF mutants:mutant RAS:GTP bind RAF1 TAS Homo sapiens 5706 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5706 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5706 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5706 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 5706 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 5706 R-HSA-9703008 https://reactome.org/PathwayBrowser/#/R-HSA-9703008 tamatinib-resistant FLT3 mutants don't bind tamatinib TAS Homo sapiens 5706 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5706 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5707 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 5707 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 5707 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 5707 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 5707 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 5707 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 5707 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 5707 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 5707 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 5707 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 5707 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 5707 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 5707 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 5707 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 5707 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 5707 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 5707 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 5707 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 5709 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 5709 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 5709 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 5709 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 5709 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 5709 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 5709 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 5709 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 5709 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 5709 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 5709 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 5709 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 5709 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 5709 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 5709 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 5709 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 5709 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 5709 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 5711 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5711 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5711 R-BTA-5213464 https://reactome.org/PathwayBrowser/#/R-BTA-5213464 RIPK1 is phosphorylated IEA Bos taurus 5711 R-BTA-5213466 https://reactome.org/PathwayBrowser/#/R-BTA-5213466 RIPK3 is phosphorylated IEA Bos taurus 5711 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5711 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5711 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5711 R-BTA-9693978 https://reactome.org/PathwayBrowser/#/R-BTA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Bos taurus 5711 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5711 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5711 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5711 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5711 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5711 R-CFA-5213464 https://reactome.org/PathwayBrowser/#/R-CFA-5213464 RIPK1 is phosphorylated IEA Canis familiaris 5711 R-CFA-5213466 https://reactome.org/PathwayBrowser/#/R-CFA-5213466 RIPK3 is phosphorylated IEA Canis familiaris 5711 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5711 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5711 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5711 R-CFA-9693978 https://reactome.org/PathwayBrowser/#/R-CFA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Canis familiaris 5711 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5711 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5711 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5711 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5711 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5711 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5711 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5711 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5711 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5711 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5711 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5711 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5711 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5711 R-HSA-5213464 https://reactome.org/PathwayBrowser/#/R-HSA-5213464 RIPK1 is phosphorylated TAS Homo sapiens 5711 R-HSA-5213466 https://reactome.org/PathwayBrowser/#/R-HSA-5213466 RIPK3 is phosphorylated TAS Homo sapiens 5711 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 5711 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5711 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5711 R-HSA-9669874 https://reactome.org/PathwayBrowser/#/R-HSA-9669874 Sorafenib-resistant KIT mutants do not bind sorafenib TAS Homo sapiens 5711 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5711 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5711 R-HSA-9674414 https://reactome.org/PathwayBrowser/#/R-HSA-9674414 Sorafenib-resistant PDGFR mutants don't bind sorefenib TAS Homo sapiens 5711 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5711 R-HSA-9693978 https://reactome.org/PathwayBrowser/#/R-HSA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 TAS Homo sapiens 5711 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 5711 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 5711 R-HSA-9702623 https://reactome.org/PathwayBrowser/#/R-HSA-9702623 sorafenib-resistant FLT3 mutants don't bind sorafenib TAS Homo sapiens 5711 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5711 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5711 R-MMU-5213464 https://reactome.org/PathwayBrowser/#/R-MMU-5213464 RIPK1 is phosphorylated IEA Mus musculus 5711 R-MMU-5213466 https://reactome.org/PathwayBrowser/#/R-MMU-5213466 RIPK3 is phosphorylated IEA Mus musculus 5711 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5711 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5711 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5711 R-MMU-9693978 https://reactome.org/PathwayBrowser/#/R-MMU-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Mus musculus 5711 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5711 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5711 R-RNO-5213464 https://reactome.org/PathwayBrowser/#/R-RNO-5213464 RIPK1 is phosphorylated IEA Rattus norvegicus 5711 R-RNO-5213466 https://reactome.org/PathwayBrowser/#/R-RNO-5213466 RIPK3 is phosphorylated IEA Rattus norvegicus 5711 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5711 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5711 R-RNO-9693978 https://reactome.org/PathwayBrowser/#/R-RNO-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Rattus norvegicus 5711 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5711 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5711 R-SSC-5213464 https://reactome.org/PathwayBrowser/#/R-SSC-5213464 RIPK1 is phosphorylated IEA Sus scrofa 5711 R-SSC-5213466 https://reactome.org/PathwayBrowser/#/R-SSC-5213466 RIPK3 is phosphorylated IEA Sus scrofa 5711 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5711 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5711 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5711 R-SSC-9693978 https://reactome.org/PathwayBrowser/#/R-SSC-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Sus scrofa 5711 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5711 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5711 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5711 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5713 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5713 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5713 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5713 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5713 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5713 R-BTA-9836702 https://reactome.org/PathwayBrowser/#/R-BTA-9836702 PKR inhibitors bind PKR IEA Bos taurus 5713 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5713 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5713 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5713 R-CEL-9836702 https://reactome.org/PathwayBrowser/#/R-CEL-9836702 PKR inhibitors bind PKR IEA Caenorhabditis elegans 5713 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5713 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5713 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5713 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5713 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5713 R-CFA-9836702 https://reactome.org/PathwayBrowser/#/R-CFA-9836702 PKR inhibitors bind PKR IEA Canis familiaris 5713 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5713 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5713 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5713 R-DME-9836702 https://reactome.org/PathwayBrowser/#/R-DME-9836702 PKR inhibitors bind PKR IEA Drosophila melanogaster 5713 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5713 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5713 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5713 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5713 R-DRE-9836702 https://reactome.org/PathwayBrowser/#/R-DRE-9836702 PKR inhibitors bind PKR IEA Danio rerio 5713 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5713 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5713 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5713 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5713 R-GGA-9836702 https://reactome.org/PathwayBrowser/#/R-GGA-9836702 PKR inhibitors bind PKR IEA Gallus gallus 5713 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5713 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5713 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5713 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5713 R-HSA-9669878 https://reactome.org/PathwayBrowser/#/R-HSA-9669878 Sunitinib-resistant KIT mutants do not bind sunitinib TAS Homo sapiens 5713 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5713 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5713 R-HSA-9674398 https://reactome.org/PathwayBrowser/#/R-HSA-9674398 D842V PDGFRA doesn't bind sunitinib TAS Homo sapiens 5713 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5713 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 5713 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 5713 R-HSA-9702629 https://reactome.org/PathwayBrowser/#/R-HSA-9702629 sunitinib-resistant FLT3 mutants don't bind sunitinib TAS Homo sapiens 5713 R-HSA-9833723 https://reactome.org/PathwayBrowser/#/R-HSA-9833723 PKR forms a dimer TAS Homo sapiens 5713 R-HSA-9836702 https://reactome.org/PathwayBrowser/#/R-HSA-9836702 PKR inhibitors bind PKR TAS Homo sapiens 5713 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5713 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5713 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5713 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5713 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5713 R-MMU-9836702 https://reactome.org/PathwayBrowser/#/R-MMU-9836702 PKR inhibitors bind PKR IEA Mus musculus 5713 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5713 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5713 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5713 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5713 R-RNO-9836702 https://reactome.org/PathwayBrowser/#/R-RNO-9836702 PKR inhibitors bind PKR IEA Rattus norvegicus 5713 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5713 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5713 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5713 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5713 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5713 R-SSC-9836702 https://reactome.org/PathwayBrowser/#/R-SSC-9836702 PKR inhibitors bind PKR IEA Sus scrofa 5713 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5713 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5713 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5713 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5713 R-XTR-9836702 https://reactome.org/PathwayBrowser/#/R-XTR-9836702 PKR inhibitors bind PKR IEA Xenopus tropicalis 5714 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 5714 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 5714 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 5714 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 5714 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 5714 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 5714 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 5714 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 5714 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 5714 R-HSA-9700114 https://reactome.org/PathwayBrowser/#/R-HSA-9700114 NVP-TAE684-resistant ALK mutants don't bind NVP-TAE684 TAS Homo sapiens 5714 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 5714 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 5714 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 5714 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 5714 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 5714 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 5714 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 5714 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 5716 R-HSA-9680408 https://reactome.org/PathwayBrowser/#/R-HSA-9680408 BRD4 binds fedratinib TAS Homo sapiens 5717 R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 5786 R-BTA-9712274 https://reactome.org/PathwayBrowser/#/R-BTA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Bos taurus 5786 R-BTA-9755505 https://reactome.org/PathwayBrowser/#/R-BTA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Bos taurus 5786 R-CEL-9712274 https://reactome.org/PathwayBrowser/#/R-CEL-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Caenorhabditis elegans 5786 R-CEL-9755505 https://reactome.org/PathwayBrowser/#/R-CEL-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Caenorhabditis elegans 5786 R-CFA-9712274 https://reactome.org/PathwayBrowser/#/R-CFA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Canis familiaris 5786 R-CFA-9755505 https://reactome.org/PathwayBrowser/#/R-CFA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Canis familiaris 5786 R-DDI-9712274 https://reactome.org/PathwayBrowser/#/R-DDI-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Dictyostelium discoideum 5786 R-DDI-9755505 https://reactome.org/PathwayBrowser/#/R-DDI-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Dictyostelium discoideum 5786 R-DME-9712274 https://reactome.org/PathwayBrowser/#/R-DME-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Drosophila melanogaster 5786 R-DME-9755505 https://reactome.org/PathwayBrowser/#/R-DME-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Drosophila melanogaster 5786 R-DRE-9712274 https://reactome.org/PathwayBrowser/#/R-DRE-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Danio rerio 5786 R-DRE-9755505 https://reactome.org/PathwayBrowser/#/R-DRE-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Danio rerio 5786 R-GGA-9712274 https://reactome.org/PathwayBrowser/#/R-GGA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Gallus gallus 5786 R-GGA-9755505 https://reactome.org/PathwayBrowser/#/R-GGA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Gallus gallus 5786 R-HSA-9712274 https://reactome.org/PathwayBrowser/#/R-HSA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 TAS Homo sapiens 5786 R-HSA-9755505 https://reactome.org/PathwayBrowser/#/R-HSA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 TAS Homo sapiens 5786 R-MMU-9712274 https://reactome.org/PathwayBrowser/#/R-MMU-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Mus musculus 5786 R-MMU-9755505 https://reactome.org/PathwayBrowser/#/R-MMU-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Mus musculus 5786 R-RNO-9712274 https://reactome.org/PathwayBrowser/#/R-RNO-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Rattus norvegicus 5786 R-RNO-9755505 https://reactome.org/PathwayBrowser/#/R-RNO-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Rattus norvegicus 5786 R-SSC-9712274 https://reactome.org/PathwayBrowser/#/R-SSC-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Sus scrofa 5786 R-SSC-9755505 https://reactome.org/PathwayBrowser/#/R-SSC-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Sus scrofa 5786 R-XTR-9712274 https://reactome.org/PathwayBrowser/#/R-XTR-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Xenopus tropicalis 5786 R-XTR-9755505 https://reactome.org/PathwayBrowser/#/R-XTR-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Xenopus tropicalis 5820 R-BTA-9726949 https://reactome.org/PathwayBrowser/#/R-BTA-9726949 PTGIR binds PTGIR agonists IEA Bos taurus 5820 R-CFA-9726949 https://reactome.org/PathwayBrowser/#/R-CFA-9726949 PTGIR binds PTGIR agonists IEA Canis familiaris 5820 R-DME-9726949 https://reactome.org/PathwayBrowser/#/R-DME-9726949 PTGIR binds PTGIR agonists IEA Drosophila melanogaster 5820 R-DRE-9726949 https://reactome.org/PathwayBrowser/#/R-DRE-9726949 PTGIR binds PTGIR agonists IEA Danio rerio 5820 R-HSA-9726949 https://reactome.org/PathwayBrowser/#/R-HSA-9726949 PTGIR binds PTGIR agonists TAS Homo sapiens 5820 R-MMU-9726949 https://reactome.org/PathwayBrowser/#/R-MMU-9726949 PTGIR binds PTGIR agonists IEA Mus musculus 5820 R-RNO-9726949 https://reactome.org/PathwayBrowser/#/R-RNO-9726949 PTGIR binds PTGIR agonists IEA Rattus norvegicus 5820 R-SSC-9726949 https://reactome.org/PathwayBrowser/#/R-SSC-9726949 PTGIR binds PTGIR agonists IEA Sus scrofa 5820 R-XTR-9726949 https://reactome.org/PathwayBrowser/#/R-XTR-9726949 PTGIR binds PTGIR agonists IEA Xenopus tropicalis 5852 R-BTA-9726949 https://reactome.org/PathwayBrowser/#/R-BTA-9726949 PTGIR binds PTGIR agonists IEA Bos taurus 5852 R-CFA-9726949 https://reactome.org/PathwayBrowser/#/R-CFA-9726949 PTGIR binds PTGIR agonists IEA Canis familiaris 5852 R-DME-9726949 https://reactome.org/PathwayBrowser/#/R-DME-9726949 PTGIR binds PTGIR agonists IEA Drosophila melanogaster 5852 R-DRE-9726949 https://reactome.org/PathwayBrowser/#/R-DRE-9726949 PTGIR binds PTGIR agonists IEA Danio rerio 5852 R-HSA-9726949 https://reactome.org/PathwayBrowser/#/R-HSA-9726949 PTGIR binds PTGIR agonists TAS Homo sapiens 5852 R-MMU-9726949 https://reactome.org/PathwayBrowser/#/R-MMU-9726949 PTGIR binds PTGIR agonists IEA Mus musculus 5852 R-RNO-9726949 https://reactome.org/PathwayBrowser/#/R-RNO-9726949 PTGIR binds PTGIR agonists IEA Rattus norvegicus 5852 R-SSC-9726949 https://reactome.org/PathwayBrowser/#/R-SSC-9726949 PTGIR binds PTGIR agonists IEA Sus scrofa 5852 R-XTR-9726949 https://reactome.org/PathwayBrowser/#/R-XTR-9726949 PTGIR binds PTGIR agonists IEA Xenopus tropicalis 5861 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 5861 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 5861 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 5861 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 5861 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 5861 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 5861 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 5861 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 5861 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 5861 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 5861 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 5861 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 5861 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 5861 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 5861 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 5861 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 5861 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 5861 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 5861 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 5861 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 587 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(25-32) binds to AGTR1 IEA Bos taurus 587 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGTR1 IEA Bos taurus 587 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(25-32) binds to AGTR1 IEA Caenorhabditis elegans 587 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGTR1 IEA Caenorhabditis elegans 587 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(25-32) binds to AGTR1 IEA Canis familiaris 587 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGTR1 IEA Canis familiaris 587 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(25-32) binds to AGTR1 IEA Drosophila melanogaster 587 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGTR1 IEA Drosophila melanogaster 587 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(25-32) binds to AGTR1 IEA Danio rerio 587 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGTR1 IEA Danio rerio 587 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(25-32) binds to AGTR1 IEA Gallus gallus 587 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGTR1 IEA Gallus gallus 587 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(25-32) binds to AGTR1 TAS Homo sapiens 587 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGTR1 TAS Homo sapiens 587 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(25-32) binds to AGTR1 IEA Mus musculus 587 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGTR1 IEA Mus musculus 587 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(25-32) binds to AGTR1 IEA Rattus norvegicus 587 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGTR1 IEA Rattus norvegicus 587 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(25-32) binds to AGTR1 IEA Sus scrofa 587 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGTR1 IEA Sus scrofa 588 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(25-32) binds to AGTR1 IEA Bos taurus 588 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGTR1 IEA Bos taurus 588 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(25-32) binds to AGTR1 IEA Caenorhabditis elegans 588 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGTR1 IEA Caenorhabditis elegans 588 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(25-32) binds to AGTR1 IEA Canis familiaris 588 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGTR1 IEA Canis familiaris 588 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(25-32) binds to AGTR1 IEA Drosophila melanogaster 588 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGTR1 IEA Drosophila melanogaster 588 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(25-32) binds to AGTR1 IEA Danio rerio 588 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGTR1 IEA Danio rerio 588 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(25-32) binds to AGTR1 IEA Gallus gallus 588 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGTR1 IEA Gallus gallus 588 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(25-32) binds to AGTR1 TAS Homo sapiens 588 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGTR1 TAS Homo sapiens 588 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(25-32) binds to AGTR1 IEA Mus musculus 588 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGTR1 IEA Mus musculus 588 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(25-32) binds to AGTR1 IEA Rattus norvegicus 588 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGTR1 IEA Rattus norvegicus 588 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(25-32) binds to AGTR1 IEA Sus scrofa 588 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGTR1 IEA Sus scrofa 5887 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5887 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 5887 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5887 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5887 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 5887 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 5887 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5887 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 5887 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5887 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 5887 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5887 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5887 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 5887 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5887 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5887 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5887 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5887 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 5887 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5887 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 5887 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5887 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 5887 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5887 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5887 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5887 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 5887 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 5887 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 5887 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5887 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 5887 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5887 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5887 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 5887 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5887 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 5887 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5887 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 5887 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5887 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 5887 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5887 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5887 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 5887 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5887 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 5887 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5887 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 589 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(25-32) binds to AGTR1 IEA Bos taurus 589 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGTR1 IEA Bos taurus 589 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(25-32) binds to AGTR1 IEA Caenorhabditis elegans 589 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGTR1 IEA Caenorhabditis elegans 589 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(25-32) binds to AGTR1 IEA Canis familiaris 589 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGTR1 IEA Canis familiaris 589 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(25-32) binds to AGTR1 IEA Drosophila melanogaster 589 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGTR1 IEA Drosophila melanogaster 589 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(25-32) binds to AGTR1 IEA Danio rerio 589 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGTR1 IEA Danio rerio 589 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(25-32) binds to AGTR1 IEA Gallus gallus 589 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGTR1 IEA Gallus gallus 589 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(25-32) binds to AGTR1 TAS Homo sapiens 589 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGTR1 TAS Homo sapiens 589 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(25-32) binds to AGTR1 IEA Mus musculus 589 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGTR1 IEA Mus musculus 589 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(25-32) binds to AGTR1 IEA Rattus norvegicus 589 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGTR1 IEA Rattus norvegicus 589 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(25-32) binds to AGTR1 IEA Sus scrofa 589 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGTR1 IEA Sus scrofa 5890 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5890 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5890 R-BTA-5213464 https://reactome.org/PathwayBrowser/#/R-BTA-5213464 RIPK1 is phosphorylated IEA Bos taurus 5890 R-BTA-5213466 https://reactome.org/PathwayBrowser/#/R-BTA-5213466 RIPK3 is phosphorylated IEA Bos taurus 5890 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 5890 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5890 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5890 R-BTA-9693978 https://reactome.org/PathwayBrowser/#/R-BTA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Bos taurus 5890 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5890 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5890 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5890 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5890 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5890 R-CFA-5213464 https://reactome.org/PathwayBrowser/#/R-CFA-5213464 RIPK1 is phosphorylated IEA Canis familiaris 5890 R-CFA-5213466 https://reactome.org/PathwayBrowser/#/R-CFA-5213466 RIPK3 is phosphorylated IEA Canis familiaris 5890 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 5890 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5890 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5890 R-CFA-9693978 https://reactome.org/PathwayBrowser/#/R-CFA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Canis familiaris 5890 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5890 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5890 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5890 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5890 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5890 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5890 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5890 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5890 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5890 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5890 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5890 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5890 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5890 R-HSA-5213464 https://reactome.org/PathwayBrowser/#/R-HSA-5213464 RIPK1 is phosphorylated TAS Homo sapiens 5890 R-HSA-5213466 https://reactome.org/PathwayBrowser/#/R-HSA-5213466 RIPK3 is phosphorylated TAS Homo sapiens 5890 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 5890 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5890 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5890 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5890 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5890 R-HSA-9679839 https://reactome.org/PathwayBrowser/#/R-HSA-9679839 RIPK1 binds ponatinib TAS Homo sapiens 5890 R-HSA-9693978 https://reactome.org/PathwayBrowser/#/R-HSA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 TAS Homo sapiens 5890 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 5890 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 5890 R-HSA-9702613 https://reactome.org/PathwayBrowser/#/R-HSA-9702613 ponatinib-resistant FLT3 mutants don't bind ponatinib TAS Homo sapiens 5890 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5890 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5890 R-MMU-5213464 https://reactome.org/PathwayBrowser/#/R-MMU-5213464 RIPK1 is phosphorylated IEA Mus musculus 5890 R-MMU-5213466 https://reactome.org/PathwayBrowser/#/R-MMU-5213466 RIPK3 is phosphorylated IEA Mus musculus 5890 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 5890 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5890 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5890 R-MMU-9693978 https://reactome.org/PathwayBrowser/#/R-MMU-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Mus musculus 5890 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5890 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5890 R-RNO-5213464 https://reactome.org/PathwayBrowser/#/R-RNO-5213464 RIPK1 is phosphorylated IEA Rattus norvegicus 5890 R-RNO-5213466 https://reactome.org/PathwayBrowser/#/R-RNO-5213466 RIPK3 is phosphorylated IEA Rattus norvegicus 5890 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5890 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5890 R-RNO-9693978 https://reactome.org/PathwayBrowser/#/R-RNO-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Rattus norvegicus 5890 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5890 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5890 R-SSC-5213464 https://reactome.org/PathwayBrowser/#/R-SSC-5213464 RIPK1 is phosphorylated IEA Sus scrofa 5890 R-SSC-5213466 https://reactome.org/PathwayBrowser/#/R-SSC-5213466 RIPK3 is phosphorylated IEA Sus scrofa 5890 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 5890 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5890 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5890 R-SSC-9693978 https://reactome.org/PathwayBrowser/#/R-SSC-9693978 Small molecule inhibitor binds RIPK1, RIPK3 IEA Sus scrofa 5890 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5890 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5890 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5890 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5891 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5891 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5891 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 5891 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5891 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5891 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 5891 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5891 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5891 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5891 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 5891 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5891 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5891 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 5891 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5891 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5891 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5891 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 5891 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5891 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5891 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5891 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 5891 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5891 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5891 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5891 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 5891 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 5891 R-HSA-9669870 https://reactome.org/PathwayBrowser/#/R-HSA-9669870 Regorafenib-resistant KIT mutants do not bind regorafenib TAS Homo sapiens 5891 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 5891 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5891 R-HSA-9674408 https://reactome.org/PathwayBrowser/#/R-HSA-9674408 Regorafenib-resistant PDGFR mutants don't bind regorafenib TAS Homo sapiens 5891 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5891 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5891 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5891 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 5891 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5891 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5891 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5891 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 5891 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5891 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5891 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5891 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 5891 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5891 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5891 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5891 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 5891 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5893 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 59 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 59 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 59 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 59 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 59 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 59 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 59 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 59 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 59 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 59 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 59 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 59 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 59 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 59 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 59 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 59 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 59 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 59 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 59 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 59 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 59 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 59 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 59 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 59 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 59 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 59 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 59 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 59 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 590 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(25-32) binds to AGTR1 IEA Bos taurus 590 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGTR1 IEA Bos taurus 590 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(25-32) binds to AGTR1 IEA Caenorhabditis elegans 590 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGTR1 IEA Caenorhabditis elegans 590 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(25-32) binds to AGTR1 IEA Canis familiaris 590 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGTR1 IEA Canis familiaris 590 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(25-32) binds to AGTR1 IEA Drosophila melanogaster 590 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGTR1 IEA Drosophila melanogaster 590 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(25-32) binds to AGTR1 IEA Danio rerio 590 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGTR1 IEA Danio rerio 590 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(25-32) binds to AGTR1 IEA Gallus gallus 590 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGTR1 IEA Gallus gallus 590 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(25-32) binds to AGTR1 TAS Homo sapiens 590 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGTR1 TAS Homo sapiens 590 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(25-32) binds to AGTR1 IEA Mus musculus 590 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGTR1 IEA Mus musculus 590 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(25-32) binds to AGTR1 IEA Rattus norvegicus 590 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGTR1 IEA Rattus norvegicus 590 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(25-32) binds to AGTR1 IEA Sus scrofa 590 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGTR1 IEA Sus scrofa 591 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(25-32) binds to AGTR1 IEA Bos taurus 591 R-BTA-6786190 https://reactome.org/PathwayBrowser/#/R-BTA-6786190 CMBL hydrolyses OM to OLMS IEA Bos taurus 591 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGTR1 IEA Bos taurus 591 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(25-32) binds to AGTR1 IEA Caenorhabditis elegans 591 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGTR1 IEA Caenorhabditis elegans 591 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(25-32) binds to AGTR1 IEA Canis familiaris 591 R-CFA-6786190 https://reactome.org/PathwayBrowser/#/R-CFA-6786190 CMBL hydrolyses OM to OLMS IEA Canis familiaris 591 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGTR1 IEA Canis familiaris 591 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(25-32) binds to AGTR1 IEA Drosophila melanogaster 591 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGTR1 IEA Drosophila melanogaster 591 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(25-32) binds to AGTR1 IEA Danio rerio 591 R-DRE-6786190 https://reactome.org/PathwayBrowser/#/R-DRE-6786190 CMBL hydrolyses OM to OLMS IEA Danio rerio 591 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGTR1 IEA Danio rerio 591 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(25-32) binds to AGTR1 IEA Gallus gallus 591 R-GGA-6786190 https://reactome.org/PathwayBrowser/#/R-GGA-6786190 CMBL hydrolyses OM to OLMS IEA Gallus gallus 591 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGTR1 IEA Gallus gallus 591 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(25-32) binds to AGTR1 TAS Homo sapiens 591 R-HSA-6786190 https://reactome.org/PathwayBrowser/#/R-HSA-6786190 CMBL hydrolyses OM to OLMS TAS Homo sapiens 591 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGTR1 TAS Homo sapiens 591 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(25-32) binds to AGTR1 IEA Mus musculus 591 R-MMU-6786190 https://reactome.org/PathwayBrowser/#/R-MMU-6786190 CMBL hydrolyses OM to OLMS IEA Mus musculus 591 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGTR1 IEA Mus musculus 591 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(25-32) binds to AGTR1 IEA Rattus norvegicus 591 R-RNO-6786190 https://reactome.org/PathwayBrowser/#/R-RNO-6786190 CMBL hydrolyses OM to OLMS IEA Rattus norvegicus 591 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGTR1 IEA Rattus norvegicus 591 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(25-32) binds to AGTR1 IEA Sus scrofa 591 R-SSC-6786190 https://reactome.org/PathwayBrowser/#/R-SSC-6786190 CMBL hydrolyses OM to OLMS IEA Sus scrofa 591 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGTR1 IEA Sus scrofa 591 R-XTR-6786190 https://reactome.org/PathwayBrowser/#/R-XTR-6786190 CMBL hydrolyses OM to OLMS IEA Xenopus tropicalis 592 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(25-32) binds to AGTR1 IEA Bos taurus 592 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGTR1 IEA Bos taurus 592 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(25-32) binds to AGTR1 IEA Caenorhabditis elegans 592 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGTR1 IEA Caenorhabditis elegans 592 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(25-32) binds to AGTR1 IEA Canis familiaris 592 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGTR1 IEA Canis familiaris 592 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(25-32) binds to AGTR1 IEA Drosophila melanogaster 592 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGTR1 IEA Drosophila melanogaster 592 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(25-32) binds to AGTR1 IEA Danio rerio 592 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGTR1 IEA Danio rerio 592 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(25-32) binds to AGTR1 IEA Gallus gallus 592 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGTR1 IEA Gallus gallus 592 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(25-32) binds to AGTR1 TAS Homo sapiens 592 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGTR1 TAS Homo sapiens 592 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(25-32) binds to AGTR1 IEA Mus musculus 592 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGTR1 IEA Mus musculus 592 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(25-32) binds to AGTR1 IEA Rattus norvegicus 592 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGTR1 IEA Rattus norvegicus 592 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(25-32) binds to AGTR1 IEA Sus scrofa 592 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGTR1 IEA Sus scrofa 5920 R-HSA-2400010 https://reactome.org/PathwayBrowser/#/R-HSA-2400010 AKT inhibitors block AKT membrane recruitment TAS Homo sapiens 5925 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5925 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5925 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5926 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5926 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5926 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5936 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 5936 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 5936 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 5936 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 5936 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 5936 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 5936 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 5936 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 5936 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 5936 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 5936 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 5936 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 5936 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 5936 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 5936 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 5936 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 5936 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 5936 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 5936 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 5936 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 5936 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 5936 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 5936 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 5936 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 5950 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 5950 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 5950 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 5950 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 5950 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 5950 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 5950 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 5950 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 5950 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 5950 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 5950 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 5950 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 5950 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 5950 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 5950 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 5950 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 5950 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 5950 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 5962 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 5962 R-BTA-9669893 https://reactome.org/PathwayBrowser/#/R-BTA-9669893 KIT binds type I TKIs IEA Bos taurus 5962 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 5962 R-CFA-9669893 https://reactome.org/PathwayBrowser/#/R-CFA-9669893 KIT binds type I TKIs IEA Canis familiaris 5962 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 5962 R-DRE-9669893 https://reactome.org/PathwayBrowser/#/R-DRE-9669893 KIT binds type I TKIs IEA Danio rerio 5962 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 5962 R-GGA-9669893 https://reactome.org/PathwayBrowser/#/R-GGA-9669893 KIT binds type I TKIs IEA Gallus gallus 5962 R-HSA-1839039 https://reactome.org/PathwayBrowser/#/R-HSA-1839039 Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation TAS Homo sapiens 5962 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 5962 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 5962 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 5962 R-HSA-9669893 https://reactome.org/PathwayBrowser/#/R-HSA-9669893 KIT binds type I TKIs TAS Homo sapiens 5962 R-HSA-9669898 https://reactome.org/PathwayBrowser/#/R-HSA-9669898 KIT mutants bind type I TKIs TAS Homo sapiens 5962 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 5962 R-MMU-9669893 https://reactome.org/PathwayBrowser/#/R-MMU-9669893 KIT binds type I TKIs IEA Mus musculus 5962 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 5962 R-RNO-9669893 https://reactome.org/PathwayBrowser/#/R-RNO-9669893 KIT binds type I TKIs IEA Rattus norvegicus 5962 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 5962 R-SSC-9669893 https://reactome.org/PathwayBrowser/#/R-SSC-9669893 KIT binds type I TKIs IEA Sus scrofa 5962 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 5962 R-XTR-9669893 https://reactome.org/PathwayBrowser/#/R-XTR-9669893 KIT binds type I TKIs IEA Xenopus tropicalis 5969 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 5969 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 5969 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 5969 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 5969 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 5969 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 5969 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 5969 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 5969 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 5969 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 5969 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 5969 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 5969 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 5969 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 5969 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 5969 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 5969 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 5969 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 5969 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 5969 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 5969 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 5969 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 5969 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 5969 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 5969 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 5969 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 5969 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 5969 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 5969 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 5976 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5976 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5976 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5977 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5977 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5977 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5978 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5978 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5978 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5979 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5979 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5979 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5980 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5980 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5980 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5984 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 5989 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5989 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5989 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 5991 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 5991 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 5991 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 60 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 60 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 60 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 60 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 60 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 60 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 60 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 60 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 60 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 60 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 6000 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 6000 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 6000 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 6004 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 6031 R-BTA-165692 https://reactome.org/PathwayBrowser/#/R-BTA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Bos taurus 6031 R-BTA-165718 https://reactome.org/PathwayBrowser/#/R-BTA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Bos taurus 6031 R-BTA-9679044 https://reactome.org/PathwayBrowser/#/R-BTA-9679044 FKBP1A binds sirolimus IEA Bos taurus 6031 R-CEL-165718 https://reactome.org/PathwayBrowser/#/R-CEL-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Caenorhabditis elegans 6031 R-CEL-9679044 https://reactome.org/PathwayBrowser/#/R-CEL-9679044 FKBP1A binds sirolimus IEA Caenorhabditis elegans 6031 R-CFA-165692 https://reactome.org/PathwayBrowser/#/R-CFA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Canis familiaris 6031 R-CFA-165718 https://reactome.org/PathwayBrowser/#/R-CFA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Canis familiaris 6031 R-CFA-9679044 https://reactome.org/PathwayBrowser/#/R-CFA-9679044 FKBP1A binds sirolimus IEA Canis familiaris 6031 R-DDI-165692 https://reactome.org/PathwayBrowser/#/R-DDI-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Dictyostelium discoideum 6031 R-DDI-165718 https://reactome.org/PathwayBrowser/#/R-DDI-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Dictyostelium discoideum 6031 R-DDI-9679044 https://reactome.org/PathwayBrowser/#/R-DDI-9679044 FKBP1A binds sirolimus IEA Dictyostelium discoideum 6031 R-DME-165692 https://reactome.org/PathwayBrowser/#/R-DME-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Drosophila melanogaster 6031 R-DME-165718 https://reactome.org/PathwayBrowser/#/R-DME-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Drosophila melanogaster 6031 R-DME-9679044 https://reactome.org/PathwayBrowser/#/R-DME-9679044 FKBP1A binds sirolimus IEA Drosophila melanogaster 6031 R-DRE-165692 https://reactome.org/PathwayBrowser/#/R-DRE-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Danio rerio 6031 R-DRE-165718 https://reactome.org/PathwayBrowser/#/R-DRE-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Danio rerio 6031 R-DRE-9679044 https://reactome.org/PathwayBrowser/#/R-DRE-9679044 FKBP1A binds sirolimus IEA Danio rerio 6031 R-GGA-165692 https://reactome.org/PathwayBrowser/#/R-GGA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Gallus gallus 6031 R-GGA-165718 https://reactome.org/PathwayBrowser/#/R-GGA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Gallus gallus 6031 R-GGA-9679044 https://reactome.org/PathwayBrowser/#/R-GGA-9679044 FKBP1A binds sirolimus IEA Gallus gallus 6031 R-HSA-165692 https://reactome.org/PathwayBrowser/#/R-HSA-165692 Phosphorylation of 4E-BP1 by activated mTORC1 TAS Homo sapiens 6031 R-HSA-165718 https://reactome.org/PathwayBrowser/#/R-HSA-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) TAS Homo sapiens 6031 R-HSA-9679044 https://reactome.org/PathwayBrowser/#/R-HSA-9679044 FKBP1A binds sirolimus TAS Homo sapiens 6031 R-MMU-165692 https://reactome.org/PathwayBrowser/#/R-MMU-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Mus musculus 6031 R-MMU-165718 https://reactome.org/PathwayBrowser/#/R-MMU-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Mus musculus 6031 R-MMU-9679044 https://reactome.org/PathwayBrowser/#/R-MMU-9679044 FKBP1A binds sirolimus IEA Mus musculus 6031 R-RNO-165692 https://reactome.org/PathwayBrowser/#/R-RNO-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Rattus norvegicus 6031 R-RNO-165718 https://reactome.org/PathwayBrowser/#/R-RNO-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Rattus norvegicus 6031 R-RNO-9679044 https://reactome.org/PathwayBrowser/#/R-RNO-9679044 FKBP1A binds sirolimus IEA Rattus norvegicus 6031 R-SCE-9679044 https://reactome.org/PathwayBrowser/#/R-SCE-9679044 FKBP1A binds sirolimus IEA Saccharomyces cerevisiae 6031 R-SPO-9679044 https://reactome.org/PathwayBrowser/#/R-SPO-9679044 FKBP1A binds sirolimus IEA Schizosaccharomyces pombe 6031 R-SSC-165692 https://reactome.org/PathwayBrowser/#/R-SSC-165692 Phosphorylation of 4E-BP1 by activated mTORC1 IEA Sus scrofa 6031 R-SSC-165718 https://reactome.org/PathwayBrowser/#/R-SSC-165718 mTORC1 phosphorylation of RPS6KB1 (S6K) IEA Sus scrofa 6031 R-SSC-9679044 https://reactome.org/PathwayBrowser/#/R-SSC-9679044 FKBP1A binds sirolimus IEA Sus scrofa 6031 R-XTR-9679044 https://reactome.org/PathwayBrowser/#/R-XTR-9679044 FKBP1A binds sirolimus IEA Xenopus tropicalis 6060 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 6063 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 6063 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 6063 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 6063 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 6063 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 6063 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 6063 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 6063 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 6193 R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 6193 R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 6193 R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 6193 R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 6193 R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 6193 R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 6193 R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 6193 R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 6193 R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 6193 R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 6193 R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 6193 R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 6193 R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 6193 R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 6193 R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 6193 R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 6193 R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 6193 R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 6193 R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 6193 R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 6277 R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 6277 R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 6277 R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 6277 R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 6277 R-BTA-5696415 https://reactome.org/PathwayBrowser/#/R-BTA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Bos taurus 6277 R-BTA-6787321 https://reactome.org/PathwayBrowser/#/R-BTA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Bos taurus 6277 R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 6277 R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 6277 R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 6277 R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 6277 R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 6277 R-CEL-5696415 https://reactome.org/PathwayBrowser/#/R-CEL-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Caenorhabditis elegans 6277 R-CEL-6787321 https://reactome.org/PathwayBrowser/#/R-CEL-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Caenorhabditis elegans 6277 R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 6277 R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 6277 R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 6277 R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 6277 R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 6277 R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 6277 R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 6277 R-CFA-5696415 https://reactome.org/PathwayBrowser/#/R-CFA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Canis familiaris 6277 R-CFA-6787321 https://reactome.org/PathwayBrowser/#/R-CFA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Canis familiaris 6277 R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 6277 R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 6277 R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 6277 R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 6277 R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 6277 R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 6277 R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 6277 R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 6277 R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 6277 R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 6277 R-DME-5696415 https://reactome.org/PathwayBrowser/#/R-DME-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Drosophila melanogaster 6277 R-DME-6787321 https://reactome.org/PathwayBrowser/#/R-DME-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Drosophila melanogaster 6277 R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 6277 R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 6277 R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 6277 R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 6277 R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 6277 R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 6277 R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 6277 R-DRE-5696415 https://reactome.org/PathwayBrowser/#/R-DRE-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Danio rerio 6277 R-DRE-6787321 https://reactome.org/PathwayBrowser/#/R-DRE-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Danio rerio 6277 R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 6277 R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 6277 R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 6277 R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 6277 R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 6277 R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 6277 R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus 6277 R-GGA-6787321 https://reactome.org/PathwayBrowser/#/R-GGA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Gallus gallus 6277 R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 6277 R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 6277 R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 6277 R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 6277 R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 6277 R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 6277 R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 6277 R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 6277 R-HSA-449872 https://reactome.org/PathwayBrowser/#/R-HSA-449872 acetaldehyde [cytosolic] => acetaldehyde [mitochondrial] TAS Homo sapiens 6277 R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 6277 R-HSA-5696415 https://reactome.org/PathwayBrowser/#/R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA TAS Homo sapiens 6277 R-HSA-6787321 https://reactome.org/PathwayBrowser/#/R-HSA-6787321 DERA cleaves dR5P to GA3P and CH3CHO TAS Homo sapiens 6277 R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 6277 R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 6277 R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 6277 R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 6277 R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 6277 R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 6277 R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 6277 R-MMU-5696415 https://reactome.org/PathwayBrowser/#/R-MMU-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Mus musculus 6277 R-MMU-6787321 https://reactome.org/PathwayBrowser/#/R-MMU-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Mus musculus 6277 R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 6277 R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 6277 R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 6277 R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 6277 R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 6277 R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 6277 R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 6277 R-RNO-5696415 https://reactome.org/PathwayBrowser/#/R-RNO-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Rattus norvegicus 6277 R-RNO-6787321 https://reactome.org/PathwayBrowser/#/R-RNO-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Rattus norvegicus 6277 R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 6277 R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 6277 R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 6277 R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 6277 R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 6277 R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 6277 R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 6277 R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 6277 R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 6277 R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 6277 R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 6277 R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 6277 R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 6277 R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 6277 R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 6277 R-SSC-5696415 https://reactome.org/PathwayBrowser/#/R-SSC-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Sus scrofa 6277 R-SSC-6787321 https://reactome.org/PathwayBrowser/#/R-SSC-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Sus scrofa 6277 R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 6277 R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 6277 R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 6277 R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 6277 R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 6277 R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 6277 R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 6277 R-XTR-5696415 https://reactome.org/PathwayBrowser/#/R-XTR-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Xenopus tropicalis 6277 R-XTR-6787321 https://reactome.org/PathwayBrowser/#/R-XTR-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Xenopus tropicalis 6277 R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 6277 R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 6277 R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 6286 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 6286 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 6286 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 6286 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 6286 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 6286 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 6286 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 6286 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 6286 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 6286 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 6286 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 6286 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 6303 R-BTA-5694071 https://reactome.org/PathwayBrowser/#/R-BTA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Bos taurus 6303 R-CFA-5694071 https://reactome.org/PathwayBrowser/#/R-CFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Canis familiaris 6303 R-DME-5694071 https://reactome.org/PathwayBrowser/#/R-DME-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Drosophila melanogaster 6303 R-DRE-5694071 https://reactome.org/PathwayBrowser/#/R-DRE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Danio rerio 6303 R-GGA-5694071 https://reactome.org/PathwayBrowser/#/R-GGA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Gallus gallus 6303 R-HSA-5694071 https://reactome.org/PathwayBrowser/#/R-HSA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH TAS Homo sapiens 6303 R-MMU-5694071 https://reactome.org/PathwayBrowser/#/R-MMU-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Mus musculus 6303 R-PFA-5694071 https://reactome.org/PathwayBrowser/#/R-PFA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Plasmodium falciparum 6303 R-RNO-5694071 https://reactome.org/PathwayBrowser/#/R-RNO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Rattus norvegicus 6303 R-SCE-5694071 https://reactome.org/PathwayBrowser/#/R-SCE-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Saccharomyces cerevisiae 6303 R-SPO-5694071 https://reactome.org/PathwayBrowser/#/R-SPO-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Schizosaccharomyces pombe 6303 R-SSC-5694071 https://reactome.org/PathwayBrowser/#/R-SSC-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Sus scrofa 6303 R-XTR-5694071 https://reactome.org/PathwayBrowser/#/R-XTR-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH IEA Xenopus tropicalis 6310 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 6310 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 6310 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 6310 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 6310 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 6310 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 6310 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 6310 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 6310 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 6310 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 6310 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 6310 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 6316 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 6316 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 6316 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 6316 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 6316 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 6316 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 6316 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 6316 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 6316 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 6316 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 6316 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 6316 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 6318 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 6318 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 6318 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 6318 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 6318 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 6318 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 6318 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 6318 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 6318 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 6318 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 6318 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 6318 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 6319 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 6319 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 6319 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 6319 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 6319 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 6319 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 6319 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 6319 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 6319 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 6319 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 6319 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 6319 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 6322 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6322 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6322 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6322 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6322 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6322 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6322 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6322 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6322 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6322 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6322 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6322 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6332 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6332 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6332 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6332 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6332 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6332 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6332 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6332 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6332 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6332 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6332 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6332 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6332 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6332 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6332 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6332 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6332 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6332 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6332 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6332 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6332 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6332 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6332 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6332 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6332 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6332 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6332 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6332 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6332 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6332 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6332 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6332 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6332 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6333 R-BTA-5688294 https://reactome.org/PathwayBrowser/#/R-BTA-5688294 SIRT5 deacetylates Cytochrome C IEA Bos taurus 6333 R-BTA-9667952 https://reactome.org/PathwayBrowser/#/R-BTA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Bos taurus 6333 R-CFA-9667952 https://reactome.org/PathwayBrowser/#/R-CFA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Canis familiaris 6333 R-DDI-5688294 https://reactome.org/PathwayBrowser/#/R-DDI-5688294 SIRT5 deacetylates Cytochrome C IEA Dictyostelium discoideum 6333 R-DME-9667952 https://reactome.org/PathwayBrowser/#/R-DME-9667952 ANKLE2 is deacetylated by SIRT2 IEA Drosophila melanogaster 6333 R-DRE-5688294 https://reactome.org/PathwayBrowser/#/R-DRE-5688294 SIRT5 deacetylates Cytochrome C IEA Danio rerio 6333 R-DRE-9667952 https://reactome.org/PathwayBrowser/#/R-DRE-9667952 ANKLE2 is deacetylated by SIRT2 IEA Danio rerio 6333 R-GGA-5688294 https://reactome.org/PathwayBrowser/#/R-GGA-5688294 SIRT5 deacetylates Cytochrome C IEA Gallus gallus 6333 R-GGA-9667952 https://reactome.org/PathwayBrowser/#/R-GGA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Gallus gallus 6333 R-HSA-5688294 https://reactome.org/PathwayBrowser/#/R-HSA-5688294 SIRT5 deacetylates Cytochrome C TAS Homo sapiens 6333 R-HSA-9667952 https://reactome.org/PathwayBrowser/#/R-HSA-9667952 ANKLE2 is deacetylated by SIRT2 TAS Homo sapiens 6333 R-MMU-5688294 https://reactome.org/PathwayBrowser/#/R-MMU-5688294 SIRT5 deacetylates Cytochrome C IEA Mus musculus 6333 R-MMU-9667952 https://reactome.org/PathwayBrowser/#/R-MMU-9667952 ANKLE2 is deacetylated by SIRT2 IEA Mus musculus 6333 R-PFA-5688294 https://reactome.org/PathwayBrowser/#/R-PFA-5688294 SIRT5 deacetylates Cytochrome C IEA Plasmodium falciparum 6333 R-RNO-5688294 https://reactome.org/PathwayBrowser/#/R-RNO-5688294 SIRT5 deacetylates Cytochrome C IEA Rattus norvegicus 6333 R-RNO-9667952 https://reactome.org/PathwayBrowser/#/R-RNO-9667952 ANKLE2 is deacetylated by SIRT2 IEA Rattus norvegicus 6333 R-SSC-5688294 https://reactome.org/PathwayBrowser/#/R-SSC-5688294 SIRT5 deacetylates Cytochrome C IEA Sus scrofa 6333 R-SSC-9667952 https://reactome.org/PathwayBrowser/#/R-SSC-9667952 ANKLE2 is deacetylated by SIRT2 IEA Sus scrofa 6333 R-XTR-5688294 https://reactome.org/PathwayBrowser/#/R-XTR-5688294 SIRT5 deacetylates Cytochrome C IEA Xenopus tropicalis 6339 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6339 R-BTA-427998 https://reactome.org/PathwayBrowser/#/R-BTA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Bos taurus 6339 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6339 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6339 R-CEL-427998 https://reactome.org/PathwayBrowser/#/R-CEL-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Caenorhabditis elegans 6339 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6339 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6339 R-CFA-427998 https://reactome.org/PathwayBrowser/#/R-CFA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Canis familiaris 6339 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6339 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6339 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6339 R-DDI-427998 https://reactome.org/PathwayBrowser/#/R-DDI-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Dictyostelium discoideum 6339 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6339 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6339 R-DME-427998 https://reactome.org/PathwayBrowser/#/R-DME-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Drosophila melanogaster 6339 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6339 R-DRE-427998 https://reactome.org/PathwayBrowser/#/R-DRE-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Danio rerio 6339 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6339 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6339 R-GGA-427998 https://reactome.org/PathwayBrowser/#/R-GGA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Gallus gallus 6339 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6339 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6339 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6339 R-HSA-427998 https://reactome.org/PathwayBrowser/#/R-HSA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs TAS Homo sapiens 6339 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6339 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6339 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6339 R-MMU-427998 https://reactome.org/PathwayBrowser/#/R-MMU-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Mus musculus 6339 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6339 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6339 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6339 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6339 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6339 R-RNO-427998 https://reactome.org/PathwayBrowser/#/R-RNO-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Rattus norvegicus 6339 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6339 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6339 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6339 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6339 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6339 R-SSC-427998 https://reactome.org/PathwayBrowser/#/R-SSC-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Sus scrofa 6339 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6339 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6339 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6344 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6344 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6344 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6344 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6344 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6344 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6344 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6344 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6344 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6344 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6344 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6344 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6344 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6344 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6344 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6344 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6344 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6344 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6344 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6344 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6344 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6344 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6344 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6344 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6344 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6344 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6344 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6344 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6344 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6344 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6344 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6344 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6344 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6344 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6344 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6344 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6344 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6344 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6344 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6344 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6344 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6344 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6344 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6344 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6344 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6344 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6344 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6344 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6344 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6344 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6344 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6344 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6344 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6350 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6350 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6350 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6350 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6350 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6350 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6350 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6350 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6350 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6350 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6350 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6350 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6352 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6352 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6352 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6352 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6352 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6352 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6352 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6352 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6352 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6352 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6352 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6352 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6352 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6352 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6352 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6352 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6352 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6352 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6352 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6352 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6352 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6352 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6352 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6352 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6352 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6352 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6352 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6352 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6352 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6352 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6352 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6352 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6352 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6360 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6360 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6360 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6360 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6360 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6360 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6360 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6360 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6360 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6360 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6360 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6360 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6360 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6360 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6360 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6360 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6360 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6360 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6360 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6360 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6367 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6367 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6367 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6367 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6367 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6367 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6367 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6367 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6367 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6367 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6367 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6367 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6373 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6373 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6373 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6373 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6373 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6373 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6373 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6373 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6373 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6373 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6373 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6373 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6373 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6373 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6373 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6373 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6373 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6373 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6373 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6373 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6373 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6373 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6373 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6373 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6373 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6373 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6373 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6373 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6373 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6373 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6373 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6373 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6373 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6374 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6374 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6374 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6374 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6374 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6374 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6374 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6374 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6374 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6374 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6374 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6374 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6375 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6375 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6375 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6375 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6375 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6375 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6375 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6375 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6375 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6375 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6375 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6375 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6375 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6375 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6375 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6375 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6375 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6375 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6375 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6375 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6375 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6375 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6375 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6375 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6375 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6375 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6375 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6375 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6375 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6375 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6375 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6375 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6375 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6377 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6377 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6377 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6377 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6377 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6377 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6377 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6377 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6377 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6377 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6377 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6377 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6378 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6378 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6378 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6378 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6378 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6378 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6378 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6378 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6378 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6378 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6378 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6378 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6378 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6378 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6378 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6378 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6378 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6378 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6378 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6378 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6378 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6378 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6378 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6378 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6378 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6378 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6378 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6378 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6378 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6378 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6378 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6378 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6378 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6380 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 6380 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 6380 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 6380 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 6380 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 6380 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 6380 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 6380 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 6380 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 6380 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 6380 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 6380 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 6380 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 6380 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 6380 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 6380 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 6380 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 6380 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 6380 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 6380 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 6380 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 6380 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 6380 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 6380 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 6380 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 6380 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 6380 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 6380 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 6380 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 6380 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 6380 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 6380 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 6382 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 6382 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 6382 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 6382 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 6382 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 6382 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 6382 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 6382 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 6382 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 6382 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 6382 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 6382 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 6382 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 6382 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 6382 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 6382 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 6382 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 6382 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 6382 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 6382 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 6382 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 6382 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 6382 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 6382 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 6382 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 6382 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 6382 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 6382 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 6382 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 6382 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 6382 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 6382 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 6385 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 6385 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 6385 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 6385 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 6385 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 6385 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 6385 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 6385 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 6385 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 6385 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 6385 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 6385 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 6385 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 6385 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 6385 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 6385 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 6385 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 6385 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 6385 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 6385 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 6385 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 6385 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 6385 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 6385 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 6385 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 6385 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 6385 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 6385 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 6385 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 6385 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 6385 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 6385 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 6388 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 6388 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 6388 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 6388 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 6388 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 6388 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 6388 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 6388 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 6388 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 6388 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 6388 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 6388 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 6388 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 6388 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 6388 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 6388 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 6388 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 6388 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 6388 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 6388 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 6388 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 6388 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 6388 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 6388 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 6388 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 6388 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 6388 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 6388 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 6388 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 6388 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 6390 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 6390 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 6390 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 6390 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 6390 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 6390 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 6390 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 6390 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 6390 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 6390 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 6390 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 6390 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 6390 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 6390 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 6390 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 6390 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 6390 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 6390 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 6390 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 6390 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 6390 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 6390 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 6390 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 6390 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 6390 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 6390 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 6390 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 6390 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 6390 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 6390 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 6412 R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 6412 R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 6412 R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 6412 R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 6412 R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 6412 R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 6412 R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 6412 R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 6412 R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 6432 R-HSA-9681514 https://reactome.org/PathwayBrowser/#/R-HSA-9681514 TMPRSS2 binds TMPRSS2 inhibitors TAS Homo sapiens 6432 R-HSA-9686731 https://reactome.org/PathwayBrowser/#/R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 6432 R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 6453 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6453 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6453 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6453 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6453 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6453 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6453 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6453 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6453 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6453 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6453 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6453 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6455 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6455 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6455 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6455 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6455 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6455 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6455 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6455 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6455 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6455 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6455 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6455 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6455 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6455 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6455 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6455 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6455 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6455 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6455 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6455 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6455 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6455 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6455 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6455 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6455 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6455 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6455 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6455 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6455 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6455 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6455 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6455 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6455 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6456 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6456 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6456 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6456 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6456 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6456 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6456 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6456 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6456 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6456 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6456 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6456 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6457 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6457 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6457 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6457 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6457 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6457 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6457 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6457 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6457 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6457 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6457 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6457 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6457 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6457 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6457 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6457 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6457 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6457 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6457 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6457 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6457 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6457 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6457 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6457 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6457 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6457 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6457 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6457 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6457 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6457 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6457 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6457 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6457 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6458 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 6458 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 6458 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 6458 R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Bos taurus 6458 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 6458 R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Canis familiaris 6458 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 6458 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 6458 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 6458 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 6458 R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Gallus gallus 6458 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 6458 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 6458 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 6458 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 6458 R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) bind IIa TAS Homo sapiens 6458 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 6458 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 6458 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 6458 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 6458 R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Mus musculus 6458 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 6458 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 6458 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 6458 R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Rattus norvegicus 6458 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 6458 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 6458 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 6458 R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Sus scrofa 6458 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 6458 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 6458 R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Xenopus tropicalis 6459 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6459 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6459 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6459 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6459 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6459 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6459 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6459 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6459 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6459 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6459 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6459 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6461 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6461 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6461 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6461 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6461 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6461 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6461 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6461 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6461 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6461 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6461 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6461 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6461 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6461 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6461 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6461 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6461 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6461 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6461 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6461 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6461 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6461 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6461 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6461 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6461 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6461 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6461 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6461 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6461 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6461 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6461 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6461 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6461 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6462 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6462 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6462 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6462 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6462 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6462 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6462 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6462 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6462 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6462 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6462 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6462 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6463 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6463 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6463 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6463 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6463 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6463 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6463 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6463 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6463 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6463 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6463 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6463 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6463 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6463 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6463 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6463 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6463 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6463 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6463 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6463 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6463 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6463 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6463 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6463 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6463 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6463 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6463 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6463 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6463 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6463 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6463 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6463 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6463 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6464 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 6464 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 6464 R-HSA-9911517 https://reactome.org/PathwayBrowser/#/R-HSA-9911517 MdfA transports tetracyclines from the cytosol to the periplasmic space TAS Homo sapiens 6464 R-HSA-9912784 https://reactome.org/PathwayBrowser/#/R-HSA-9912784 Tetracycline antibiotics bind to 16S rRNA TAS Homo sapiens 6464 R-HSA-9913106 https://reactome.org/PathwayBrowser/#/R-HSA-9913106 TetB exports tetracyclines TAS Homo sapiens 6464 R-HSA-9913128 https://reactome.org/PathwayBrowser/#/R-HSA-9913128 TetA exports tetracyclines TAS Homo sapiens 6469 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 6469 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 6469 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 6469 R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Bos taurus 6469 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 6469 R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Canis familiaris 6469 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 6469 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 6469 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 6469 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 6469 R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Gallus gallus 6469 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 6469 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 6469 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 6469 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 6469 R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) bind IIa TAS Homo sapiens 6469 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 6469 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 6469 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 6469 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 6469 R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Mus musculus 6469 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 6469 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 6469 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 6469 R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Rattus norvegicus 6469 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 6469 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 6469 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 6469 R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Sus scrofa 6469 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 6469 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 6469 R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Xenopus tropicalis 6470 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 6470 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 6470 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 6470 R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Bos taurus 6470 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 6470 R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Canis familiaris 6470 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 6470 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 6470 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 6470 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 6470 R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Gallus gallus 6470 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 6470 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 6470 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 6470 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 6470 R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) bind IIa TAS Homo sapiens 6470 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 6470 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 6470 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 6470 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 6470 R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Mus musculus 6470 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 6470 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 6470 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 6470 R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Rattus norvegicus 6470 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 6470 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 6470 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 6470 R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Sus scrofa 6470 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 6470 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 6470 R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Xenopus tropicalis 6494 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 6495 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 6495 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 6495 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 6495 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 6495 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 6495 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 6495 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 6495 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 6495 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 6495 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 6495 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 6495 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 6495 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 6495 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 6495 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 6495 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 6495 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 6495 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 6495 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 6495 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 6495 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 6495 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 6495 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 6495 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 6495 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 6495 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 6495 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 6510 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6510 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6510 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6510 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6510 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6510 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6510 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6510 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6510 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6510 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6510 R-HSA-9911510 https://reactome.org/PathwayBrowser/#/R-HSA-9911510 MacA:MacB:TolC transports azithromycin from the periplasm to the extracellular region TAS Homo sapiens 6510 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 6510 R-HSA-9911514 https://reactome.org/PathwayBrowser/#/R-HSA-9911514 MacA:MacB:TolC transports azithromycin from the cytosol to the periplasm TAS Homo sapiens 6510 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 6510 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6510 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6510 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6510 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6510 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6510 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6510 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6510 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6510 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6510 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6531 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 6531 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 6531 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 6531 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 6531 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 6531 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 6531 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 6531 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 6531 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 6531 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 6531 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 6531 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 6531 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 6531 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 6531 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 6531 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 6531 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 6531 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 6531 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 6531 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 6531 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 6551 R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 6551 R-BTA-191366 https://reactome.org/PathwayBrowser/#/R-BTA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Bos taurus 6551 R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 6551 R-CFA-191366 https://reactome.org/PathwayBrowser/#/R-CFA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Canis familiaris 6551 R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 6551 R-DDI-191366 https://reactome.org/PathwayBrowser/#/R-DDI-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Dictyostelium discoideum 6551 R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 6551 R-DRE-191366 https://reactome.org/PathwayBrowser/#/R-DRE-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Danio rerio 6551 R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 6551 R-GGA-191366 https://reactome.org/PathwayBrowser/#/R-GGA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Gallus gallus 6551 R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 6551 R-HSA-191366 https://reactome.org/PathwayBrowser/#/R-HSA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol TAS Homo sapiens 6551 R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 6551 R-MMU-191366 https://reactome.org/PathwayBrowser/#/R-MMU-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Mus musculus 6551 R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 6551 R-RNO-191366 https://reactome.org/PathwayBrowser/#/R-RNO-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Rattus norvegicus 6551 R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 6551 R-SCE-191366 https://reactome.org/PathwayBrowser/#/R-SCE-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Saccharomyces cerevisiae 6551 R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 6551 R-SPO-191366 https://reactome.org/PathwayBrowser/#/R-SPO-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Schizosaccharomyces pombe 6551 R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 6551 R-SSC-191366 https://reactome.org/PathwayBrowser/#/R-SSC-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Sus scrofa 6551 R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 6551 R-XTR-191366 https://reactome.org/PathwayBrowser/#/R-XTR-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol IEA Xenopus tropicalis 6569 R-BTA-9712274 https://reactome.org/PathwayBrowser/#/R-BTA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Bos taurus 6569 R-BTA-9755505 https://reactome.org/PathwayBrowser/#/R-BTA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Bos taurus 6569 R-CEL-9712274 https://reactome.org/PathwayBrowser/#/R-CEL-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Caenorhabditis elegans 6569 R-CEL-9755505 https://reactome.org/PathwayBrowser/#/R-CEL-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Caenorhabditis elegans 6569 R-CFA-9712274 https://reactome.org/PathwayBrowser/#/R-CFA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Canis familiaris 6569 R-CFA-9755505 https://reactome.org/PathwayBrowser/#/R-CFA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Canis familiaris 6569 R-DDI-9712274 https://reactome.org/PathwayBrowser/#/R-DDI-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Dictyostelium discoideum 6569 R-DDI-9755505 https://reactome.org/PathwayBrowser/#/R-DDI-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Dictyostelium discoideum 6569 R-DME-9712274 https://reactome.org/PathwayBrowser/#/R-DME-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Drosophila melanogaster 6569 R-DME-9755505 https://reactome.org/PathwayBrowser/#/R-DME-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Drosophila melanogaster 6569 R-DRE-9712274 https://reactome.org/PathwayBrowser/#/R-DRE-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Danio rerio 6569 R-DRE-9755505 https://reactome.org/PathwayBrowser/#/R-DRE-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Danio rerio 6569 R-GGA-9712274 https://reactome.org/PathwayBrowser/#/R-GGA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Gallus gallus 6569 R-GGA-9755505 https://reactome.org/PathwayBrowser/#/R-GGA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Gallus gallus 6569 R-HSA-9712274 https://reactome.org/PathwayBrowser/#/R-HSA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 TAS Homo sapiens 6569 R-HSA-9755505 https://reactome.org/PathwayBrowser/#/R-HSA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 TAS Homo sapiens 6569 R-MMU-9712274 https://reactome.org/PathwayBrowser/#/R-MMU-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Mus musculus 6569 R-MMU-9755505 https://reactome.org/PathwayBrowser/#/R-MMU-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Mus musculus 6569 R-RNO-9712274 https://reactome.org/PathwayBrowser/#/R-RNO-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Rattus norvegicus 6569 R-RNO-9755505 https://reactome.org/PathwayBrowser/#/R-RNO-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Rattus norvegicus 6569 R-SSC-9712274 https://reactome.org/PathwayBrowser/#/R-SSC-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Sus scrofa 6569 R-SSC-9755505 https://reactome.org/PathwayBrowser/#/R-SSC-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Sus scrofa 6569 R-XTR-9712274 https://reactome.org/PathwayBrowser/#/R-XTR-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Xenopus tropicalis 6569 R-XTR-9755505 https://reactome.org/PathwayBrowser/#/R-XTR-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Xenopus tropicalis 6570 R-BTA-9724745 https://reactome.org/PathwayBrowser/#/R-BTA-9724745 PLG(20-810) binds aprotinin IEA Bos taurus 6570 R-CFA-9724745 https://reactome.org/PathwayBrowser/#/R-CFA-9724745 PLG(20-810) binds aprotinin IEA Canis familiaris 6570 R-GGA-9724745 https://reactome.org/PathwayBrowser/#/R-GGA-9724745 PLG(20-810) binds aprotinin IEA Gallus gallus 6570 R-HSA-9724745 https://reactome.org/PathwayBrowser/#/R-HSA-9724745 PLG(20-810) binds aprotinin TAS Homo sapiens 6570 R-MMU-9724745 https://reactome.org/PathwayBrowser/#/R-MMU-9724745 PLG(20-810) binds aprotinin IEA Mus musculus 6570 R-RNO-9724745 https://reactome.org/PathwayBrowser/#/R-RNO-9724745 PLG(20-810) binds aprotinin IEA Rattus norvegicus 6570 R-SSC-9724745 https://reactome.org/PathwayBrowser/#/R-SSC-9724745 PLG(20-810) binds aprotinin IEA Sus scrofa 6571 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6571 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6571 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6571 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6571 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6571 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6571 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6571 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6571 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6571 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6571 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6571 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6572 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6572 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6572 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6572 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6572 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6572 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6572 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6572 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6572 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6572 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6572 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6572 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6572 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6572 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6572 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6572 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6572 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6572 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6572 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6572 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6572 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6572 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6572 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6572 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6572 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6572 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6572 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6572 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6572 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6572 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6572 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6572 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6572 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6573 R-BTA-9724753 https://reactome.org/PathwayBrowser/#/R-BTA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Bos taurus 6573 R-CFA-9724753 https://reactome.org/PathwayBrowser/#/R-CFA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Canis familiaris 6573 R-GGA-9724753 https://reactome.org/PathwayBrowser/#/R-GGA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Gallus gallus 6573 R-HSA-9724753 https://reactome.org/PathwayBrowser/#/R-HSA-9724753 PLG(20-810) binds anti-fibrinolytics TAS Homo sapiens 6573 R-MMU-9724753 https://reactome.org/PathwayBrowser/#/R-MMU-9724753 PLG(20-810) binds anti-fibrinolytics IEA Mus musculus 6573 R-RNO-9724753 https://reactome.org/PathwayBrowser/#/R-RNO-9724753 PLG(20-810) binds anti-fibrinolytics IEA Rattus norvegicus 6573 R-SSC-9724753 https://reactome.org/PathwayBrowser/#/R-SSC-9724753 PLG(20-810) binds anti-fibrinolytics IEA Sus scrofa 6574 R-BTA-9724753 https://reactome.org/PathwayBrowser/#/R-BTA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Bos taurus 6574 R-CFA-9724753 https://reactome.org/PathwayBrowser/#/R-CFA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Canis familiaris 6574 R-GGA-9724753 https://reactome.org/PathwayBrowser/#/R-GGA-9724753 PLG(20-810) binds anti-fibrinolytics IEA Gallus gallus 6574 R-HSA-9724753 https://reactome.org/PathwayBrowser/#/R-HSA-9724753 PLG(20-810) binds anti-fibrinolytics TAS Homo sapiens 6574 R-MMU-9724753 https://reactome.org/PathwayBrowser/#/R-MMU-9724753 PLG(20-810) binds anti-fibrinolytics IEA Mus musculus 6574 R-RNO-9724753 https://reactome.org/PathwayBrowser/#/R-RNO-9724753 PLG(20-810) binds anti-fibrinolytics IEA Rattus norvegicus 6574 R-SSC-9724753 https://reactome.org/PathwayBrowser/#/R-SSC-9724753 PLG(20-810) binds anti-fibrinolytics IEA Sus scrofa 6575 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6575 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6575 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6575 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6575 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6575 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6575 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6575 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6575 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6575 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6575 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6575 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6576 R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Bos taurus 6576 R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 6576 R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 6576 R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Caenorhabditis elegans 6576 R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 6576 R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 6576 R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Canis familiaris 6576 R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 6576 R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 6576 R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 6576 R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Drosophila melanogaster 6576 R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 6576 R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 6576 R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 6576 R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Gallus gallus 6576 R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 6576 R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 6576 R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) TAS Homo sapiens 6576 R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 6576 R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 6576 R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 6576 R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Mus musculus 6576 R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 6576 R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 6576 R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Rattus norvegicus 6576 R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 6576 R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 6576 R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Sus scrofa 6576 R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 6576 R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 6576 R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) IEA Xenopus tropicalis 6576 R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 6576 R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 6585 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 6591 R-BTA-198941 https://reactome.org/PathwayBrowser/#/R-BTA-198941 VCAM1 binds Integrin alpha4beta1 IEA Bos taurus 6591 R-BTA-202706 https://reactome.org/PathwayBrowser/#/R-BTA-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Bos taurus 6591 R-BTA-9679740 https://reactome.org/PathwayBrowser/#/R-BTA-9679740 ITGA4:ITGB1 binds natalizumab IEA Bos taurus 6591 R-CEL-9679740 https://reactome.org/PathwayBrowser/#/R-CEL-9679740 ITGA4:ITGB1 binds natalizumab IEA Caenorhabditis elegans 6591 R-CFA-198941 https://reactome.org/PathwayBrowser/#/R-CFA-198941 VCAM1 binds Integrin alpha4beta1 IEA Canis familiaris 6591 R-CFA-202706 https://reactome.org/PathwayBrowser/#/R-CFA-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Canis familiaris 6591 R-CFA-9679740 https://reactome.org/PathwayBrowser/#/R-CFA-9679740 ITGA4:ITGB1 binds natalizumab IEA Canis familiaris 6591 R-DME-9679740 https://reactome.org/PathwayBrowser/#/R-DME-9679740 ITGA4:ITGB1 binds natalizumab IEA Drosophila melanogaster 6591 R-DRE-198941 https://reactome.org/PathwayBrowser/#/R-DRE-198941 VCAM1 binds Integrin alpha4beta1 IEA Danio rerio 6591 R-DRE-202706 https://reactome.org/PathwayBrowser/#/R-DRE-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Danio rerio 6591 R-DRE-9679740 https://reactome.org/PathwayBrowser/#/R-DRE-9679740 ITGA4:ITGB1 binds natalizumab IEA Danio rerio 6591 R-GGA-202706 https://reactome.org/PathwayBrowser/#/R-GGA-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Gallus gallus 6591 R-GGA-9679740 https://reactome.org/PathwayBrowser/#/R-GGA-9679740 ITGA4:ITGB1 binds natalizumab IEA Gallus gallus 6591 R-HSA-198941 https://reactome.org/PathwayBrowser/#/R-HSA-198941 VCAM1 binds Integrin alpha4beta1 TAS Homo sapiens 6591 R-HSA-202706 https://reactome.org/PathwayBrowser/#/R-HSA-202706 Integrin alpha4beta1 binds JAM2:JAM3 TAS Homo sapiens 6591 R-HSA-9679740 https://reactome.org/PathwayBrowser/#/R-HSA-9679740 ITGA4:ITGB1 binds natalizumab TAS Homo sapiens 6591 R-MMU-198941 https://reactome.org/PathwayBrowser/#/R-MMU-198941 VCAM1 binds Integrin alpha4beta1 IEA Mus musculus 6591 R-MMU-202706 https://reactome.org/PathwayBrowser/#/R-MMU-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Mus musculus 6591 R-MMU-9679740 https://reactome.org/PathwayBrowser/#/R-MMU-9679740 ITGA4:ITGB1 binds natalizumab IEA Mus musculus 6591 R-RNO-198941 https://reactome.org/PathwayBrowser/#/R-RNO-198941 VCAM1 binds Integrin alpha4beta1 IEA Rattus norvegicus 6591 R-RNO-202706 https://reactome.org/PathwayBrowser/#/R-RNO-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Rattus norvegicus 6591 R-RNO-9679740 https://reactome.org/PathwayBrowser/#/R-RNO-9679740 ITGA4:ITGB1 binds natalizumab IEA Rattus norvegicus 6591 R-SSC-198941 https://reactome.org/PathwayBrowser/#/R-SSC-198941 VCAM1 binds Integrin alpha4beta1 IEA Sus scrofa 6591 R-SSC-202706 https://reactome.org/PathwayBrowser/#/R-SSC-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Sus scrofa 6591 R-SSC-9679740 https://reactome.org/PathwayBrowser/#/R-SSC-9679740 ITGA4:ITGB1 binds natalizumab IEA Sus scrofa 6591 R-XTR-202706 https://reactome.org/PathwayBrowser/#/R-XTR-202706 Integrin alpha4beta1 binds JAM2:JAM3 IEA Xenopus tropicalis 6591 R-XTR-9679740 https://reactome.org/PathwayBrowser/#/R-XTR-9679740 ITGA4:ITGB1 binds natalizumab IEA Xenopus tropicalis 6598 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 6598 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 6598 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 6598 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 6598 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 6598 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 6598 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 6598 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 6598 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 6598 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 6598 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 6598 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 6598 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 6598 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 6598 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 6599 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 6599 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 6599 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 6599 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 6599 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 6599 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 6599 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 6599 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 6599 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 6599 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 6599 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 6599 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 6599 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 6599 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 6599 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 6602 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 6602 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 6602 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 6602 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 6602 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 6602 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 6602 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 6602 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 6602 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 6602 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 6602 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 6602 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 6602 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 6602 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 6602 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 6604 R-BTA-71249 https://reactome.org/PathwayBrowser/#/R-BTA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Bos taurus 6604 R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 6604 R-CEL-71249 https://reactome.org/PathwayBrowser/#/R-CEL-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Caenorhabditis elegans 6604 R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 6604 R-CFA-71249 https://reactome.org/PathwayBrowser/#/R-CFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Canis familiaris 6604 R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 6604 R-DDI-71249 https://reactome.org/PathwayBrowser/#/R-DDI-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Dictyostelium discoideum 6604 R-DME-71249 https://reactome.org/PathwayBrowser/#/R-DME-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Drosophila melanogaster 6604 R-DRE-71249 https://reactome.org/PathwayBrowser/#/R-DRE-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Danio rerio 6604 R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 6604 R-GGA-71249 https://reactome.org/PathwayBrowser/#/R-GGA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Gallus gallus 6604 R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 6604 R-HSA-71249 https://reactome.org/PathwayBrowser/#/R-HSA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly TAS Homo sapiens 6604 R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 6604 R-MMU-71249 https://reactome.org/PathwayBrowser/#/R-MMU-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Mus musculus 6604 R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 6604 R-PFA-71249 https://reactome.org/PathwayBrowser/#/R-PFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Plasmodium falciparum 6604 R-RNO-71249 https://reactome.org/PathwayBrowser/#/R-RNO-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Rattus norvegicus 6604 R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 6604 R-SSC-71249 https://reactome.org/PathwayBrowser/#/R-SSC-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Sus scrofa 6604 R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 6604 R-XTR-71249 https://reactome.org/PathwayBrowser/#/R-XTR-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Xenopus tropicalis 6604 R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 6605 R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 6605 R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 6605 R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 6605 R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 6605 R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 6605 R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 6605 R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 6605 R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 6605 R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 6605 R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 6605 R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 6605 R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 6605 R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 6605 R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 6605 R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 6605 R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 6605 R-RNO-71261 https://reactome.org/PathwayBrowser/#/R-RNO-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Rattus norvegicus 6605 R-SCE-71261 https://reactome.org/PathwayBrowser/#/R-SCE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Saccharomyces cerevisiae 6605 R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 6605 R-SSC-71261 https://reactome.org/PathwayBrowser/#/R-SSC-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Sus scrofa 6605 R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 6605 R-XTR-71261 https://reactome.org/PathwayBrowser/#/R-XTR-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Xenopus tropicalis 6608 R-BTA-880002 https://reactome.org/PathwayBrowser/#/R-BTA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Bos taurus 6608 R-BTA-880033 https://reactome.org/PathwayBrowser/#/R-BTA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Bos taurus 6608 R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 6608 R-BTA-916855 https://reactome.org/PathwayBrowser/#/R-BTA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Bos taurus 6608 R-CEL-880002 https://reactome.org/PathwayBrowser/#/R-CEL-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Caenorhabditis elegans 6608 R-CEL-880033 https://reactome.org/PathwayBrowser/#/R-CEL-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Caenorhabditis elegans 6608 R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 6608 R-CEL-916855 https://reactome.org/PathwayBrowser/#/R-CEL-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Caenorhabditis elegans 6608 R-CFA-880002 https://reactome.org/PathwayBrowser/#/R-CFA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Canis familiaris 6608 R-CFA-880033 https://reactome.org/PathwayBrowser/#/R-CFA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Canis familiaris 6608 R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 6608 R-CFA-916855 https://reactome.org/PathwayBrowser/#/R-CFA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Canis familiaris 6608 R-DDI-880002 https://reactome.org/PathwayBrowser/#/R-DDI-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Dictyostelium discoideum 6608 R-DDI-880033 https://reactome.org/PathwayBrowser/#/R-DDI-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Dictyostelium discoideum 6608 R-DDI-916855 https://reactome.org/PathwayBrowser/#/R-DDI-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Dictyostelium discoideum 6608 R-DME-880002 https://reactome.org/PathwayBrowser/#/R-DME-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Drosophila melanogaster 6608 R-DME-880033 https://reactome.org/PathwayBrowser/#/R-DME-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Drosophila melanogaster 6608 R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 6608 R-DME-916855 https://reactome.org/PathwayBrowser/#/R-DME-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Drosophila melanogaster 6608 R-DRE-880002 https://reactome.org/PathwayBrowser/#/R-DRE-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Danio rerio 6608 R-DRE-880033 https://reactome.org/PathwayBrowser/#/R-DRE-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Danio rerio 6608 R-DRE-916855 https://reactome.org/PathwayBrowser/#/R-DRE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Danio rerio 6608 R-GGA-880002 https://reactome.org/PathwayBrowser/#/R-GGA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Gallus gallus 6608 R-GGA-880033 https://reactome.org/PathwayBrowser/#/R-GGA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Gallus gallus 6608 R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 6608 R-GGA-916855 https://reactome.org/PathwayBrowser/#/R-GGA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Gallus gallus 6608 R-HSA-880002 https://reactome.org/PathwayBrowser/#/R-HSA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate TAS Homo sapiens 6608 R-HSA-880033 https://reactome.org/PathwayBrowser/#/R-HSA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde TAS Homo sapiens 6608 R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 6608 R-HSA-916855 https://reactome.org/PathwayBrowser/#/R-HSA-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA TAS Homo sapiens 6608 R-MMU-880002 https://reactome.org/PathwayBrowser/#/R-MMU-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Mus musculus 6608 R-MMU-880033 https://reactome.org/PathwayBrowser/#/R-MMU-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Mus musculus 6608 R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 6608 R-MMU-916855 https://reactome.org/PathwayBrowser/#/R-MMU-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Mus musculus 6608 R-RNO-880002 https://reactome.org/PathwayBrowser/#/R-RNO-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Rattus norvegicus 6608 R-RNO-880033 https://reactome.org/PathwayBrowser/#/R-RNO-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Rattus norvegicus 6608 R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 6608 R-RNO-916855 https://reactome.org/PathwayBrowser/#/R-RNO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Rattus norvegicus 6608 R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 6608 R-SCE-916855 https://reactome.org/PathwayBrowser/#/R-SCE-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Saccharomyces cerevisiae 6608 R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 6608 R-SPO-916855 https://reactome.org/PathwayBrowser/#/R-SPO-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Schizosaccharomyces pombe 6608 R-SSC-880002 https://reactome.org/PathwayBrowser/#/R-SSC-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Sus scrofa 6608 R-SSC-880033 https://reactome.org/PathwayBrowser/#/R-SSC-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Sus scrofa 6608 R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 6608 R-SSC-916855 https://reactome.org/PathwayBrowser/#/R-SSC-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Sus scrofa 6608 R-XTR-880002 https://reactome.org/PathwayBrowser/#/R-XTR-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate IEA Xenopus tropicalis 6608 R-XTR-880033 https://reactome.org/PathwayBrowser/#/R-XTR-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde IEA Xenopus tropicalis 6608 R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 6608 R-XTR-916855 https://reactome.org/PathwayBrowser/#/R-XTR-916855 PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA IEA Xenopus tropicalis 6621 R-BTA-428681 https://reactome.org/PathwayBrowser/#/R-BTA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Bos taurus 6621 R-CEL-428681 https://reactome.org/PathwayBrowser/#/R-CEL-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Caenorhabditis elegans 6621 R-CFA-428681 https://reactome.org/PathwayBrowser/#/R-CFA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Canis familiaris 6621 R-DDI-428681 https://reactome.org/PathwayBrowser/#/R-DDI-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Dictyostelium discoideum 6621 R-DME-428681 https://reactome.org/PathwayBrowser/#/R-DME-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Drosophila melanogaster 6621 R-GGA-428681 https://reactome.org/PathwayBrowser/#/R-GGA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Gallus gallus 6621 R-GGA-433606 https://reactome.org/PathwayBrowser/#/R-GGA-433606 sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP IEA Gallus gallus 6621 R-HSA-428681 https://reactome.org/PathwayBrowser/#/R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates TAS Homo sapiens 6621 R-MMU-428681 https://reactome.org/PathwayBrowser/#/R-MMU-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Mus musculus 6621 R-RNO-428681 https://reactome.org/PathwayBrowser/#/R-RNO-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Rattus norvegicus 6621 R-SCE-428681 https://reactome.org/PathwayBrowser/#/R-SCE-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Saccharomyces cerevisiae 6621 R-SSC-428681 https://reactome.org/PathwayBrowser/#/R-SSC-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Sus scrofa 6621 R-XTR-428681 https://reactome.org/PathwayBrowser/#/R-XTR-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Xenopus tropicalis 6624 R-BTA-9695917 https://reactome.org/PathwayBrowser/#/R-BTA-9695917 SPHK2 binds SPHK2 inhibitors IEA Bos taurus 6624 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 6624 R-CEL-9695917 https://reactome.org/PathwayBrowser/#/R-CEL-9695917 SPHK2 binds SPHK2 inhibitors IEA Caenorhabditis elegans 6624 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 6624 R-CFA-9695917 https://reactome.org/PathwayBrowser/#/R-CFA-9695917 SPHK2 binds SPHK2 inhibitors IEA Canis familiaris 6624 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 6624 R-DDI-9695917 https://reactome.org/PathwayBrowser/#/R-DDI-9695917 SPHK2 binds SPHK2 inhibitors IEA Dictyostelium discoideum 6624 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 6624 R-DME-9695917 https://reactome.org/PathwayBrowser/#/R-DME-9695917 SPHK2 binds SPHK2 inhibitors IEA Drosophila melanogaster 6624 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 6624 R-HSA-9695917 https://reactome.org/PathwayBrowser/#/R-HSA-9695917 SPHK2 binds SPHK2 inhibitors TAS Homo sapiens 6624 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 6624 R-MMU-9695917 https://reactome.org/PathwayBrowser/#/R-MMU-9695917 SPHK2 binds SPHK2 inhibitors IEA Mus musculus 6624 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 6624 R-RNO-9695917 https://reactome.org/PathwayBrowser/#/R-RNO-9695917 SPHK2 binds SPHK2 inhibitors IEA Rattus norvegicus 6624 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 6624 R-SCE-9695917 https://reactome.org/PathwayBrowser/#/R-SCE-9695917 SPHK2 binds SPHK2 inhibitors IEA Saccharomyces cerevisiae 6624 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 6624 R-SPO-9695917 https://reactome.org/PathwayBrowser/#/R-SPO-9695917 SPHK2 binds SPHK2 inhibitors IEA Schizosaccharomyces pombe 6624 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 6624 R-SSC-9695917 https://reactome.org/PathwayBrowser/#/R-SSC-9695917 SPHK2 binds SPHK2 inhibitors IEA Sus scrofa 6624 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 6624 R-XTR-9695917 https://reactome.org/PathwayBrowser/#/R-XTR-9695917 SPHK2 binds SPHK2 inhibitors IEA Xenopus tropicalis 6624 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 6625 R-BTA-9695917 https://reactome.org/PathwayBrowser/#/R-BTA-9695917 SPHK2 binds SPHK2 inhibitors IEA Bos taurus 6625 R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 6625 R-CEL-9695917 https://reactome.org/PathwayBrowser/#/R-CEL-9695917 SPHK2 binds SPHK2 inhibitors IEA Caenorhabditis elegans 6625 R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 6625 R-CFA-9695917 https://reactome.org/PathwayBrowser/#/R-CFA-9695917 SPHK2 binds SPHK2 inhibitors IEA Canis familiaris 6625 R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 6625 R-DDI-9695917 https://reactome.org/PathwayBrowser/#/R-DDI-9695917 SPHK2 binds SPHK2 inhibitors IEA Dictyostelium discoideum 6625 R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 6625 R-DME-9695917 https://reactome.org/PathwayBrowser/#/R-DME-9695917 SPHK2 binds SPHK2 inhibitors IEA Drosophila melanogaster 6625 R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 6625 R-HSA-9695917 https://reactome.org/PathwayBrowser/#/R-HSA-9695917 SPHK2 binds SPHK2 inhibitors TAS Homo sapiens 6625 R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 6625 R-MMU-9695917 https://reactome.org/PathwayBrowser/#/R-MMU-9695917 SPHK2 binds SPHK2 inhibitors IEA Mus musculus 6625 R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 6625 R-RNO-9695917 https://reactome.org/PathwayBrowser/#/R-RNO-9695917 SPHK2 binds SPHK2 inhibitors IEA Rattus norvegicus 6625 R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 6625 R-SCE-9695917 https://reactome.org/PathwayBrowser/#/R-SCE-9695917 SPHK2 binds SPHK2 inhibitors IEA Saccharomyces cerevisiae 6625 R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 6625 R-SPO-9695917 https://reactome.org/PathwayBrowser/#/R-SPO-9695917 SPHK2 binds SPHK2 inhibitors IEA Schizosaccharomyces pombe 6625 R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 6625 R-SSC-9695917 https://reactome.org/PathwayBrowser/#/R-SSC-9695917 SPHK2 binds SPHK2 inhibitors IEA Sus scrofa 6625 R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 6625 R-XTR-9695917 https://reactome.org/PathwayBrowser/#/R-XTR-9695917 SPHK2 binds SPHK2 inhibitors IEA Xenopus tropicalis 6625 R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 6627 R-BTA-428681 https://reactome.org/PathwayBrowser/#/R-BTA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Bos taurus 6627 R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 6627 R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 6627 R-CEL-428681 https://reactome.org/PathwayBrowser/#/R-CEL-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Caenorhabditis elegans 6627 R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 6627 R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 6627 R-CFA-428681 https://reactome.org/PathwayBrowser/#/R-CFA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Canis familiaris 6627 R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 6627 R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 6627 R-DDI-428681 https://reactome.org/PathwayBrowser/#/R-DDI-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Dictyostelium discoideum 6627 R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 6627 R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 6627 R-DME-428681 https://reactome.org/PathwayBrowser/#/R-DME-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Drosophila melanogaster 6627 R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 6627 R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 6627 R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 6627 R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 6627 R-GGA-428681 https://reactome.org/PathwayBrowser/#/R-GGA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Gallus gallus 6627 R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 6627 R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 6627 R-HSA-428681 https://reactome.org/PathwayBrowser/#/R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates TAS Homo sapiens 6627 R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 6627 R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 6627 R-MMU-428681 https://reactome.org/PathwayBrowser/#/R-MMU-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Mus musculus 6627 R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 6627 R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 6627 R-RNO-428681 https://reactome.org/PathwayBrowser/#/R-RNO-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Rattus norvegicus 6627 R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 6627 R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 6627 R-SCE-428681 https://reactome.org/PathwayBrowser/#/R-SCE-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Saccharomyces cerevisiae 6627 R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 6627 R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 6627 R-SSC-428681 https://reactome.org/PathwayBrowser/#/R-SSC-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Sus scrofa 6627 R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 6627 R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 6627 R-XTR-428681 https://reactome.org/PathwayBrowser/#/R-XTR-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates IEA Xenopus tropicalis 6627 R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 6627 R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 6635 R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 6635 R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 6635 R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 6635 R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 6635 R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 6635 R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 6635 R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 6635 R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 6635 R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 6635 R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 6635 R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 6635 R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 6635 R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 6635 R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 6635 R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 6635 R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 6638 R-BTA-9677917 https://reactome.org/PathwayBrowser/#/R-BTA-9677917 MAOA inhibitors bind MAOA:FAD IEA Bos taurus 6638 R-CFA-9677917 https://reactome.org/PathwayBrowser/#/R-CFA-9677917 MAOA inhibitors bind MAOA:FAD IEA Canis familiaris 6638 R-DDI-9677917 https://reactome.org/PathwayBrowser/#/R-DDI-9677917 MAOA inhibitors bind MAOA:FAD IEA Dictyostelium discoideum 6638 R-GGA-9677917 https://reactome.org/PathwayBrowser/#/R-GGA-9677917 MAOA inhibitors bind MAOA:FAD IEA Gallus gallus 6638 R-HSA-9677917 https://reactome.org/PathwayBrowser/#/R-HSA-9677917 MAOA inhibitors bind MAOA:FAD TAS Homo sapiens 6638 R-MMU-9677917 https://reactome.org/PathwayBrowser/#/R-MMU-9677917 MAOA inhibitors bind MAOA:FAD IEA Mus musculus 6638 R-RNO-9677917 https://reactome.org/PathwayBrowser/#/R-RNO-9677917 MAOA inhibitors bind MAOA:FAD IEA Rattus norvegicus 6638 R-SSC-9677917 https://reactome.org/PathwayBrowser/#/R-SSC-9677917 MAOA inhibitors bind MAOA:FAD IEA Sus scrofa 6639 R-BTA-9677917 https://reactome.org/PathwayBrowser/#/R-BTA-9677917 MAOA inhibitors bind MAOA:FAD IEA Bos taurus 6639 R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus 6639 R-CFA-9677917 https://reactome.org/PathwayBrowser/#/R-CFA-9677917 MAOA inhibitors bind MAOA:FAD IEA Canis familiaris 6639 R-CFA-9677929 https://reactome.org/PathwayBrowser/#/R-CFA-9677929 MAOB inhibitors bind MAOB:FAD IEA Canis familiaris 6639 R-DDI-9677917 https://reactome.org/PathwayBrowser/#/R-DDI-9677917 MAOA inhibitors bind MAOA:FAD IEA Dictyostelium discoideum 6639 R-DDI-9677929 https://reactome.org/PathwayBrowser/#/R-DDI-9677929 MAOB inhibitors bind MAOB:FAD IEA Dictyostelium discoideum 6639 R-DRE-9677929 https://reactome.org/PathwayBrowser/#/R-DRE-9677929 MAOB inhibitors bind MAOB:FAD IEA Danio rerio 6639 R-GGA-9677917 https://reactome.org/PathwayBrowser/#/R-GGA-9677917 MAOA inhibitors bind MAOA:FAD IEA Gallus gallus 6639 R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus 6639 R-HSA-9677917 https://reactome.org/PathwayBrowser/#/R-HSA-9677917 MAOA inhibitors bind MAOA:FAD TAS Homo sapiens 6639 R-HSA-9677929 https://reactome.org/PathwayBrowser/#/R-HSA-9677929 MAOB inhibitors bind MAOB:FAD TAS Homo sapiens 6639 R-MMU-9677917 https://reactome.org/PathwayBrowser/#/R-MMU-9677917 MAOA inhibitors bind MAOA:FAD IEA Mus musculus 6639 R-MMU-9677929 https://reactome.org/PathwayBrowser/#/R-MMU-9677929 MAOB inhibitors bind MAOB:FAD IEA Mus musculus 6639 R-RNO-9677917 https://reactome.org/PathwayBrowser/#/R-RNO-9677917 MAOA inhibitors bind MAOA:FAD IEA Rattus norvegicus 6639 R-RNO-9677929 https://reactome.org/PathwayBrowser/#/R-RNO-9677929 MAOB inhibitors bind MAOB:FAD IEA Rattus norvegicus 6639 R-SSC-9677917 https://reactome.org/PathwayBrowser/#/R-SSC-9677917 MAOA inhibitors bind MAOA:FAD IEA Sus scrofa 6639 R-SSC-9677929 https://reactome.org/PathwayBrowser/#/R-SSC-9677929 MAOB inhibitors bind MAOB:FAD IEA Sus scrofa 6639 R-XTR-9677929 https://reactome.org/PathwayBrowser/#/R-XTR-9677929 MAOB inhibitors bind MAOB:FAD IEA Xenopus tropicalis 6641 R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus 6641 R-CFA-9677929 https://reactome.org/PathwayBrowser/#/R-CFA-9677929 MAOB inhibitors bind MAOB:FAD IEA Canis familiaris 6641 R-DDI-9677929 https://reactome.org/PathwayBrowser/#/R-DDI-9677929 MAOB inhibitors bind MAOB:FAD IEA Dictyostelium discoideum 6641 R-DRE-9677929 https://reactome.org/PathwayBrowser/#/R-DRE-9677929 MAOB inhibitors bind MAOB:FAD IEA Danio rerio 6641 R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus 6641 R-HSA-9677929 https://reactome.org/PathwayBrowser/#/R-HSA-9677929 MAOB inhibitors bind MAOB:FAD TAS Homo sapiens 6641 R-MMU-9677929 https://reactome.org/PathwayBrowser/#/R-MMU-9677929 MAOB inhibitors bind MAOB:FAD IEA Mus musculus 6641 R-RNO-9677929 https://reactome.org/PathwayBrowser/#/R-RNO-9677929 MAOB inhibitors bind MAOB:FAD IEA Rattus norvegicus 6641 R-SSC-9677929 https://reactome.org/PathwayBrowser/#/R-SSC-9677929 MAOB inhibitors bind MAOB:FAD IEA Sus scrofa 6641 R-XTR-9677929 https://reactome.org/PathwayBrowser/#/R-XTR-9677929 MAOB inhibitors bind MAOB:FAD IEA Xenopus tropicalis 6646 R-BTA-379387 https://reactome.org/PathwayBrowser/#/R-BTA-379387 COMT transfers Met to DA to form 3MT IEA Bos taurus 6646 R-BTA-9679775 https://reactome.org/PathwayBrowser/#/R-BTA-9679775 COMT binds COMT Inhibitors IEA Bos taurus 6646 R-CFA-379387 https://reactome.org/PathwayBrowser/#/R-CFA-379387 COMT transfers Met to DA to form 3MT IEA Canis familiaris 6646 R-CFA-9679775 https://reactome.org/PathwayBrowser/#/R-CFA-9679775 COMT binds COMT Inhibitors IEA Canis familiaris 6646 R-DRE-379387 https://reactome.org/PathwayBrowser/#/R-DRE-379387 COMT transfers Met to DA to form 3MT IEA Danio rerio 6646 R-DRE-9679775 https://reactome.org/PathwayBrowser/#/R-DRE-9679775 COMT binds COMT Inhibitors IEA Danio rerio 6646 R-GGA-379387 https://reactome.org/PathwayBrowser/#/R-GGA-379387 COMT transfers Met to DA to form 3MT IEA Gallus gallus 6646 R-GGA-9679775 https://reactome.org/PathwayBrowser/#/R-GGA-9679775 COMT binds COMT Inhibitors IEA Gallus gallus 6646 R-HSA-379387 https://reactome.org/PathwayBrowser/#/R-HSA-379387 COMT transfers Met to DA to form 3MT TAS Homo sapiens 6646 R-HSA-9679775 https://reactome.org/PathwayBrowser/#/R-HSA-9679775 COMT binds COMT Inhibitors TAS Homo sapiens 6646 R-MMU-379387 https://reactome.org/PathwayBrowser/#/R-MMU-379387 COMT transfers Met to DA to form 3MT IEA Mus musculus 6646 R-MMU-9679775 https://reactome.org/PathwayBrowser/#/R-MMU-9679775 COMT binds COMT Inhibitors IEA Mus musculus 6646 R-RNO-379387 https://reactome.org/PathwayBrowser/#/R-RNO-379387 COMT transfers Met to DA to form 3MT IEA Rattus norvegicus 6646 R-RNO-9679775 https://reactome.org/PathwayBrowser/#/R-RNO-9679775 COMT binds COMT Inhibitors IEA Rattus norvegicus 6646 R-SPO-379387 https://reactome.org/PathwayBrowser/#/R-SPO-379387 COMT transfers Met to DA to form 3MT IEA Schizosaccharomyces pombe 6646 R-SPO-9679775 https://reactome.org/PathwayBrowser/#/R-SPO-9679775 COMT binds COMT Inhibitors IEA Schizosaccharomyces pombe 6646 R-SSC-379387 https://reactome.org/PathwayBrowser/#/R-SSC-379387 COMT transfers Met to DA to form 3MT IEA Sus scrofa 6646 R-SSC-9679775 https://reactome.org/PathwayBrowser/#/R-SSC-9679775 COMT binds COMT Inhibitors IEA Sus scrofa 6646 R-XTR-379387 https://reactome.org/PathwayBrowser/#/R-XTR-379387 COMT transfers Met to DA to form 3MT IEA Xenopus tropicalis 6646 R-XTR-9679775 https://reactome.org/PathwayBrowser/#/R-XTR-9679775 COMT binds COMT Inhibitors IEA Xenopus tropicalis 6647 R-BTA-379387 https://reactome.org/PathwayBrowser/#/R-BTA-379387 COMT transfers Met to DA to form 3MT IEA Bos taurus 6647 R-BTA-9679775 https://reactome.org/PathwayBrowser/#/R-BTA-9679775 COMT binds COMT Inhibitors IEA Bos taurus 6647 R-CFA-379387 https://reactome.org/PathwayBrowser/#/R-CFA-379387 COMT transfers Met to DA to form 3MT IEA Canis familiaris 6647 R-CFA-9679775 https://reactome.org/PathwayBrowser/#/R-CFA-9679775 COMT binds COMT Inhibitors IEA Canis familiaris 6647 R-DRE-379387 https://reactome.org/PathwayBrowser/#/R-DRE-379387 COMT transfers Met to DA to form 3MT IEA Danio rerio 6647 R-DRE-9679775 https://reactome.org/PathwayBrowser/#/R-DRE-9679775 COMT binds COMT Inhibitors IEA Danio rerio 6647 R-GGA-379387 https://reactome.org/PathwayBrowser/#/R-GGA-379387 COMT transfers Met to DA to form 3MT IEA Gallus gallus 6647 R-GGA-9679775 https://reactome.org/PathwayBrowser/#/R-GGA-9679775 COMT binds COMT Inhibitors IEA Gallus gallus 6647 R-HSA-379387 https://reactome.org/PathwayBrowser/#/R-HSA-379387 COMT transfers Met to DA to form 3MT TAS Homo sapiens 6647 R-HSA-9679775 https://reactome.org/PathwayBrowser/#/R-HSA-9679775 COMT binds COMT Inhibitors TAS Homo sapiens 6647 R-MMU-379387 https://reactome.org/PathwayBrowser/#/R-MMU-379387 COMT transfers Met to DA to form 3MT IEA Mus musculus 6647 R-MMU-9679775 https://reactome.org/PathwayBrowser/#/R-MMU-9679775 COMT binds COMT Inhibitors IEA Mus musculus 6647 R-RNO-379387 https://reactome.org/PathwayBrowser/#/R-RNO-379387 COMT transfers Met to DA to form 3MT IEA Rattus norvegicus 6647 R-RNO-9679775 https://reactome.org/PathwayBrowser/#/R-RNO-9679775 COMT binds COMT Inhibitors IEA Rattus norvegicus 6647 R-SPO-379387 https://reactome.org/PathwayBrowser/#/R-SPO-379387 COMT transfers Met to DA to form 3MT IEA Schizosaccharomyces pombe 6647 R-SPO-9679775 https://reactome.org/PathwayBrowser/#/R-SPO-9679775 COMT binds COMT Inhibitors IEA Schizosaccharomyces pombe 6647 R-SSC-379387 https://reactome.org/PathwayBrowser/#/R-SSC-379387 COMT transfers Met to DA to form 3MT IEA Sus scrofa 6647 R-SSC-9679775 https://reactome.org/PathwayBrowser/#/R-SSC-9679775 COMT binds COMT Inhibitors IEA Sus scrofa 6647 R-XTR-379387 https://reactome.org/PathwayBrowser/#/R-XTR-379387 COMT transfers Met to DA to form 3MT IEA Xenopus tropicalis 6647 R-XTR-9679775 https://reactome.org/PathwayBrowser/#/R-XTR-9679775 COMT binds COMT Inhibitors IEA Xenopus tropicalis 6654 R-GGA-433550 https://reactome.org/PathwayBrowser/#/R-GGA-433550 palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2 IEA Gallus gallus 6654 R-GGA-433576 https://reactome.org/PathwayBrowser/#/R-GGA-433576 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ IEA Gallus gallus 6661 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 6661 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 6661 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 6661 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 6661 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 6661 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 6661 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 6661 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 6661 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 6661 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 6661 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 6661 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 6661 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 6661 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 6661 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 6661 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 6661 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 6661 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 6669 R-BTA-2454081 https://reactome.org/PathwayBrowser/#/R-BTA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Bos taurus 6669 R-BTA-2454113 https://reactome.org/PathwayBrowser/#/R-BTA-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Bos taurus 6669 R-BTA-2454118 https://reactome.org/PathwayBrowser/#/R-BTA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Bos taurus 6669 R-BTA-2465924 https://reactome.org/PathwayBrowser/#/R-BTA-2465924 OPN1LW binds 11cRAL IEA Bos taurus 6669 R-BTA-5362721 https://reactome.org/PathwayBrowser/#/R-BTA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Bos taurus 6669 R-BTA-74872 https://reactome.org/PathwayBrowser/#/R-BTA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Bos taurus 6669 R-BTA-8960973 https://reactome.org/PathwayBrowser/#/R-BTA-8960973 RLBP1:11cRAL dissociates IEA Bos taurus 6669 R-BTA-9656891 https://reactome.org/PathwayBrowser/#/R-BTA-9656891 OPN1SW binds 11cRAL IEA Bos taurus 6669 R-BTA-9656893 https://reactome.org/PathwayBrowser/#/R-BTA-9656893 OPN1MW binds 11cRAL IEA Bos taurus 6669 R-CEL-2454118 https://reactome.org/PathwayBrowser/#/R-CEL-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Caenorhabditis elegans 6669 R-CEL-2465924 https://reactome.org/PathwayBrowser/#/R-CEL-2465924 OPN1LW binds 11cRAL IEA Caenorhabditis elegans 6669 R-CEL-5362721 https://reactome.org/PathwayBrowser/#/R-CEL-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Caenorhabditis elegans 6669 R-CEL-9656891 https://reactome.org/PathwayBrowser/#/R-CEL-9656891 OPN1SW binds 11cRAL IEA Caenorhabditis elegans 6669 R-CEL-9656893 https://reactome.org/PathwayBrowser/#/R-CEL-9656893 OPN1MW binds 11cRAL IEA Caenorhabditis elegans 6669 R-CFA-2454081 https://reactome.org/PathwayBrowser/#/R-CFA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Canis familiaris 6669 R-CFA-2454113 https://reactome.org/PathwayBrowser/#/R-CFA-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Canis familiaris 6669 R-CFA-2454118 https://reactome.org/PathwayBrowser/#/R-CFA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Canis familiaris 6669 R-CFA-2465924 https://reactome.org/PathwayBrowser/#/R-CFA-2465924 OPN1LW binds 11cRAL IEA Canis familiaris 6669 R-CFA-5362721 https://reactome.org/PathwayBrowser/#/R-CFA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Canis familiaris 6669 R-CFA-74872 https://reactome.org/PathwayBrowser/#/R-CFA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Canis familiaris 6669 R-CFA-8960973 https://reactome.org/PathwayBrowser/#/R-CFA-8960973 RLBP1:11cRAL dissociates IEA Canis familiaris 6669 R-CFA-9656891 https://reactome.org/PathwayBrowser/#/R-CFA-9656891 OPN1SW binds 11cRAL IEA Canis familiaris 6669 R-CFA-9656893 https://reactome.org/PathwayBrowser/#/R-CFA-9656893 OPN1MW binds 11cRAL IEA Canis familiaris 6669 R-DDI-8960973 https://reactome.org/PathwayBrowser/#/R-DDI-8960973 RLBP1:11cRAL dissociates IEA Dictyostelium discoideum 6669 R-DME-5362721 https://reactome.org/PathwayBrowser/#/R-DME-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 6669 R-DME-74872 https://reactome.org/PathwayBrowser/#/R-DME-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 6669 R-DME-8960973 https://reactome.org/PathwayBrowser/#/R-DME-8960973 RLBP1:11cRAL dissociates IEA Drosophila melanogaster 6669 R-DRE-2454081 https://reactome.org/PathwayBrowser/#/R-DRE-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Danio rerio 6669 R-DRE-2454118 https://reactome.org/PathwayBrowser/#/R-DRE-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Danio rerio 6669 R-DRE-2465924 https://reactome.org/PathwayBrowser/#/R-DRE-2465924 OPN1LW binds 11cRAL IEA Danio rerio 6669 R-DRE-5362721 https://reactome.org/PathwayBrowser/#/R-DRE-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Danio rerio 6669 R-DRE-74872 https://reactome.org/PathwayBrowser/#/R-DRE-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Danio rerio 6669 R-DRE-8960973 https://reactome.org/PathwayBrowser/#/R-DRE-8960973 RLBP1:11cRAL dissociates IEA Danio rerio 6669 R-DRE-9656891 https://reactome.org/PathwayBrowser/#/R-DRE-9656891 OPN1SW binds 11cRAL IEA Danio rerio 6669 R-DRE-9656893 https://reactome.org/PathwayBrowser/#/R-DRE-9656893 OPN1MW binds 11cRAL IEA Danio rerio 6669 R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus 6669 R-GGA-2454113 https://reactome.org/PathwayBrowser/#/R-GGA-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Gallus gallus 6669 R-GGA-2454118 https://reactome.org/PathwayBrowser/#/R-GGA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Gallus gallus 6669 R-GGA-2465924 https://reactome.org/PathwayBrowser/#/R-GGA-2465924 OPN1LW binds 11cRAL IEA Gallus gallus 6669 R-GGA-5362721 https://reactome.org/PathwayBrowser/#/R-GGA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Gallus gallus 6669 R-GGA-74872 https://reactome.org/PathwayBrowser/#/R-GGA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Gallus gallus 6669 R-GGA-8960973 https://reactome.org/PathwayBrowser/#/R-GGA-8960973 RLBP1:11cRAL dissociates IEA Gallus gallus 6669 R-GGA-9656893 https://reactome.org/PathwayBrowser/#/R-GGA-9656893 OPN1MW binds 11cRAL IEA Gallus gallus 6669 R-HSA-2454081 https://reactome.org/PathwayBrowser/#/R-HSA-2454081 RDH5 oxidises 11cROL to 11cRAL TAS Homo sapiens 6669 R-HSA-2454113 https://reactome.org/PathwayBrowser/#/R-HSA-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment TAS Homo sapiens 6669 R-HSA-2454118 https://reactome.org/PathwayBrowser/#/R-HSA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO TAS Homo sapiens 6669 R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 6669 R-HSA-2465924 https://reactome.org/PathwayBrowser/#/R-HSA-2465924 OPN1LW binds 11cRAL TAS Homo sapiens 6669 R-HSA-2466706 https://reactome.org/PathwayBrowser/#/R-HSA-2466706 Defective OPN1MW does not bind 11cRAL TAS Homo sapiens 6669 R-HSA-2466822 https://reactome.org/PathwayBrowser/#/R-HSA-2466822 Defective OPN1LW does not bind 11cRAL TAS Homo sapiens 6669 R-HSA-2466834 https://reactome.org/PathwayBrowser/#/R-HSA-2466834 Defective OPN1SW does not bind 11cRAL TAS Homo sapiens 6669 R-HSA-5362721 https://reactome.org/PathwayBrowser/#/R-HSA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL TAS Homo sapiens 6669 R-HSA-74872 https://reactome.org/PathwayBrowser/#/R-HSA-74872 RDH10,11 oxidise 11cROL to 11cRAL TAS Homo sapiens 6669 R-HSA-8960973 https://reactome.org/PathwayBrowser/#/R-HSA-8960973 RLBP1:11cRAL dissociates TAS Homo sapiens 6669 R-HSA-9656891 https://reactome.org/PathwayBrowser/#/R-HSA-9656891 OPN1SW binds 11cRAL TAS Homo sapiens 6669 R-HSA-9656893 https://reactome.org/PathwayBrowser/#/R-HSA-9656893 OPN1MW binds 11cRAL TAS Homo sapiens 6669 R-MMU-2454081 https://reactome.org/PathwayBrowser/#/R-MMU-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Mus musculus 6669 R-MMU-2454113 https://reactome.org/PathwayBrowser/#/R-MMU-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Mus musculus 6669 R-MMU-2454118 https://reactome.org/PathwayBrowser/#/R-MMU-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Mus musculus 6669 R-MMU-2465924 https://reactome.org/PathwayBrowser/#/R-MMU-2465924 OPN1LW binds 11cRAL IEA Mus musculus 6669 R-MMU-5362721 https://reactome.org/PathwayBrowser/#/R-MMU-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Mus musculus 6669 R-MMU-74872 https://reactome.org/PathwayBrowser/#/R-MMU-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Mus musculus 6669 R-MMU-8960973 https://reactome.org/PathwayBrowser/#/R-MMU-8960973 RLBP1:11cRAL dissociates IEA Mus musculus 6669 R-MMU-9656891 https://reactome.org/PathwayBrowser/#/R-MMU-9656891 OPN1SW binds 11cRAL IEA Mus musculus 6669 R-MMU-9656893 https://reactome.org/PathwayBrowser/#/R-MMU-9656893 OPN1MW binds 11cRAL IEA Mus musculus 6669 R-RNO-2454113 https://reactome.org/PathwayBrowser/#/R-RNO-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Rattus norvegicus 6669 R-RNO-2454118 https://reactome.org/PathwayBrowser/#/R-RNO-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Rattus norvegicus 6669 R-RNO-2465924 https://reactome.org/PathwayBrowser/#/R-RNO-2465924 OPN1LW binds 11cRAL IEA Rattus norvegicus 6669 R-RNO-5362721 https://reactome.org/PathwayBrowser/#/R-RNO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 6669 R-RNO-74872 https://reactome.org/PathwayBrowser/#/R-RNO-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 6669 R-RNO-8960973 https://reactome.org/PathwayBrowser/#/R-RNO-8960973 RLBP1:11cRAL dissociates IEA Rattus norvegicus 6669 R-RNO-9656891 https://reactome.org/PathwayBrowser/#/R-RNO-9656891 OPN1SW binds 11cRAL IEA Rattus norvegicus 6669 R-RNO-9656893 https://reactome.org/PathwayBrowser/#/R-RNO-9656893 OPN1MW binds 11cRAL IEA Rattus norvegicus 6669 R-SPO-5362721 https://reactome.org/PathwayBrowser/#/R-SPO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Schizosaccharomyces pombe 6669 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa 6669 R-SSC-2454113 https://reactome.org/PathwayBrowser/#/R-SSC-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Sus scrofa 6669 R-SSC-2454118 https://reactome.org/PathwayBrowser/#/R-SSC-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Sus scrofa 6669 R-SSC-2465924 https://reactome.org/PathwayBrowser/#/R-SSC-2465924 OPN1LW binds 11cRAL IEA Sus scrofa 6669 R-SSC-5362721 https://reactome.org/PathwayBrowser/#/R-SSC-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Sus scrofa 6669 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa 6669 R-SSC-8960973 https://reactome.org/PathwayBrowser/#/R-SSC-8960973 RLBP1:11cRAL dissociates IEA Sus scrofa 6669 R-SSC-9656891 https://reactome.org/PathwayBrowser/#/R-SSC-9656891 OPN1SW binds 11cRAL IEA Sus scrofa 6669 R-SSC-9656893 https://reactome.org/PathwayBrowser/#/R-SSC-9656893 OPN1MW binds 11cRAL IEA Sus scrofa 6669 R-XTR-2454081 https://reactome.org/PathwayBrowser/#/R-XTR-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Xenopus tropicalis 6669 R-XTR-2454113 https://reactome.org/PathwayBrowser/#/R-XTR-2454113 RBP3 transports 11cRAL to rod photoreceptor outer segment IEA Xenopus tropicalis 6669 R-XTR-2465924 https://reactome.org/PathwayBrowser/#/R-XTR-2465924 OPN1LW binds 11cRAL IEA Xenopus tropicalis 6669 R-XTR-5362721 https://reactome.org/PathwayBrowser/#/R-XTR-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 6669 R-XTR-74872 https://reactome.org/PathwayBrowser/#/R-XTR-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 6669 R-XTR-8960973 https://reactome.org/PathwayBrowser/#/R-XTR-8960973 RLBP1:11cRAL dissociates IEA Xenopus tropicalis 6669 R-XTR-9656891 https://reactome.org/PathwayBrowser/#/R-XTR-9656891 OPN1SW binds 11cRAL IEA Xenopus tropicalis 6669 R-XTR-9656893 https://reactome.org/PathwayBrowser/#/R-XTR-9656893 OPN1MW binds 11cRAL IEA Xenopus tropicalis 6670 R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 6670 R-BTA-2454081 https://reactome.org/PathwayBrowser/#/R-BTA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Bos taurus 6670 R-BTA-2454264 https://reactome.org/PathwayBrowser/#/R-BTA-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Bos taurus 6670 R-BTA-2465919 https://reactome.org/PathwayBrowser/#/R-BTA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Bos taurus 6670 R-BTA-2465934 https://reactome.org/PathwayBrowser/#/R-BTA-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Bos taurus 6670 R-BTA-5362721 https://reactome.org/PathwayBrowser/#/R-BTA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Bos taurus 6670 R-BTA-74872 https://reactome.org/PathwayBrowser/#/R-BTA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Bos taurus 6670 R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 6670 R-CEL-5362721 https://reactome.org/PathwayBrowser/#/R-CEL-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Caenorhabditis elegans 6670 R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 6670 R-CFA-2454081 https://reactome.org/PathwayBrowser/#/R-CFA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Canis familiaris 6670 R-CFA-2454264 https://reactome.org/PathwayBrowser/#/R-CFA-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Canis familiaris 6670 R-CFA-2465919 https://reactome.org/PathwayBrowser/#/R-CFA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Canis familiaris 6670 R-CFA-2465934 https://reactome.org/PathwayBrowser/#/R-CFA-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Canis familiaris 6670 R-CFA-5362721 https://reactome.org/PathwayBrowser/#/R-CFA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Canis familiaris 6670 R-CFA-74872 https://reactome.org/PathwayBrowser/#/R-CFA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Canis familiaris 6670 R-DDI-2454264 https://reactome.org/PathwayBrowser/#/R-DDI-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Dictyostelium discoideum 6670 R-DDI-2465919 https://reactome.org/PathwayBrowser/#/R-DDI-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Dictyostelium discoideum 6670 R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 6670 R-DME-2454264 https://reactome.org/PathwayBrowser/#/R-DME-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Drosophila melanogaster 6670 R-DME-2465919 https://reactome.org/PathwayBrowser/#/R-DME-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Drosophila melanogaster 6670 R-DME-5362721 https://reactome.org/PathwayBrowser/#/R-DME-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 6670 R-DME-74872 https://reactome.org/PathwayBrowser/#/R-DME-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 6670 R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 6670 R-DRE-2454081 https://reactome.org/PathwayBrowser/#/R-DRE-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Danio rerio 6670 R-DRE-2454264 https://reactome.org/PathwayBrowser/#/R-DRE-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Danio rerio 6670 R-DRE-2465919 https://reactome.org/PathwayBrowser/#/R-DRE-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Danio rerio 6670 R-DRE-5362721 https://reactome.org/PathwayBrowser/#/R-DRE-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Danio rerio 6670 R-DRE-74872 https://reactome.org/PathwayBrowser/#/R-DRE-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Danio rerio 6670 R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 6670 R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus 6670 R-GGA-2454264 https://reactome.org/PathwayBrowser/#/R-GGA-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Gallus gallus 6670 R-GGA-2465919 https://reactome.org/PathwayBrowser/#/R-GGA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Gallus gallus 6670 R-GGA-2465929 https://reactome.org/PathwayBrowser/#/R-GGA-2465929 Isomerase II isomerises atROL to 11cROL TAS Gallus gallus 6670 R-GGA-2465934 https://reactome.org/PathwayBrowser/#/R-GGA-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Gallus gallus 6670 R-GGA-2465974 https://reactome.org/PathwayBrowser/#/R-GGA-2465974 An REH hydrolyses 11cRE to 11cROL TAS Gallus gallus 6670 R-GGA-5362721 https://reactome.org/PathwayBrowser/#/R-GGA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Gallus gallus 6670 R-GGA-74872 https://reactome.org/PathwayBrowser/#/R-GGA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Gallus gallus 6670 R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 6670 R-HSA-2454081 https://reactome.org/PathwayBrowser/#/R-HSA-2454081 RDH5 oxidises 11cROL to 11cRAL TAS Homo sapiens 6670 R-HSA-2454264 https://reactome.org/PathwayBrowser/#/R-HSA-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL TAS Homo sapiens 6670 R-HSA-2465919 https://reactome.org/PathwayBrowser/#/R-HSA-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM TAS Homo sapiens 6670 R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 6670 R-HSA-2465926 https://reactome.org/PathwayBrowser/#/R-HSA-2465926 An atROL isomerase isomerises atROL to 11cROL IEA Homo sapiens 6670 R-HSA-2465934 https://reactome.org/PathwayBrowser/#/R-HSA-2465934 11cROL translocates from Muller cells to cone photoreceptor cells TAS Homo sapiens 6670 R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 6670 R-HSA-2466832 https://reactome.org/PathwayBrowser/#/R-HSA-2466832 Defective RDH5 does not oxidise 11cROL to 11cRAL and causes RPA TAS Homo sapiens 6670 R-HSA-5362721 https://reactome.org/PathwayBrowser/#/R-HSA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL TAS Homo sapiens 6670 R-HSA-74872 https://reactome.org/PathwayBrowser/#/R-HSA-74872 RDH10,11 oxidise 11cROL to 11cRAL TAS Homo sapiens 6670 R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 6670 R-MMU-2454081 https://reactome.org/PathwayBrowser/#/R-MMU-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Mus musculus 6670 R-MMU-2454264 https://reactome.org/PathwayBrowser/#/R-MMU-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Mus musculus 6670 R-MMU-2465919 https://reactome.org/PathwayBrowser/#/R-MMU-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Mus musculus 6670 R-MMU-2465934 https://reactome.org/PathwayBrowser/#/R-MMU-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Mus musculus 6670 R-MMU-5362721 https://reactome.org/PathwayBrowser/#/R-MMU-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Mus musculus 6670 R-MMU-74872 https://reactome.org/PathwayBrowser/#/R-MMU-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Mus musculus 6670 R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 6670 R-RNO-2454264 https://reactome.org/PathwayBrowser/#/R-RNO-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Rattus norvegicus 6670 R-RNO-2465919 https://reactome.org/PathwayBrowser/#/R-RNO-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Rattus norvegicus 6670 R-RNO-2465934 https://reactome.org/PathwayBrowser/#/R-RNO-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Rattus norvegicus 6670 R-RNO-5362721 https://reactome.org/PathwayBrowser/#/R-RNO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 6670 R-RNO-74872 https://reactome.org/PathwayBrowser/#/R-RNO-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 6670 R-SPO-5362721 https://reactome.org/PathwayBrowser/#/R-SPO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Schizosaccharomyces pombe 6670 R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 6670 R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa 6670 R-SSC-2454264 https://reactome.org/PathwayBrowser/#/R-SSC-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Sus scrofa 6670 R-SSC-2465919 https://reactome.org/PathwayBrowser/#/R-SSC-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Sus scrofa 6670 R-SSC-2465934 https://reactome.org/PathwayBrowser/#/R-SSC-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Sus scrofa 6670 R-SSC-5362721 https://reactome.org/PathwayBrowser/#/R-SSC-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Sus scrofa 6670 R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa 6670 R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 6670 R-XTR-2454081 https://reactome.org/PathwayBrowser/#/R-XTR-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Xenopus tropicalis 6670 R-XTR-2454264 https://reactome.org/PathwayBrowser/#/R-XTR-2454264 11cROL binds to RLBP1 to form RLBP1:11cROL IEA Xenopus tropicalis 6670 R-XTR-2465919 https://reactome.org/PathwayBrowser/#/R-XTR-2465919 AWAT2 transfers PALM to 11cROL forming 11cRPALM IEA Xenopus tropicalis 6670 R-XTR-2465934 https://reactome.org/PathwayBrowser/#/R-XTR-2465934 11cROL translocates from Muller cells to cone photoreceptor cells IEA Xenopus tropicalis 6670 R-XTR-5362721 https://reactome.org/PathwayBrowser/#/R-XTR-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 6670 R-XTR-74872 https://reactome.org/PathwayBrowser/#/R-XTR-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 6687 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 6687 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 6687 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 6687 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 6687 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 6687 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 6687 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 6687 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 6687 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 6687 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 6687 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 6687 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 6687 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 6687 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 6687 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 6693 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 6693 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 6693 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 6693 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 6693 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 6693 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 6693 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 6693 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 6693 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 6693 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 6693 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 6693 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 6693 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 6693 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 6693 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 6705 R-BTA-9756134 https://reactome.org/PathwayBrowser/#/R-BTA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Bos taurus 6705 R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 6705 R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 6705 R-DDI-9756134 https://reactome.org/PathwayBrowser/#/R-DDI-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Dictyostelium discoideum 6705 R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 6705 R-GGA-9756134 https://reactome.org/PathwayBrowser/#/R-GGA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Gallus gallus 6705 R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 6705 R-HSA-9756134 https://reactome.org/PathwayBrowser/#/R-HSA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL TAS Homo sapiens 6705 R-HSA-9756136 https://reactome.org/PathwayBrowser/#/R-HSA-9756136 PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV IEA Homo sapiens 6705 R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 6705 R-MMU-9756134 https://reactome.org/PathwayBrowser/#/R-MMU-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Mus musculus 6705 R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 6705 R-RNO-9756134 https://reactome.org/PathwayBrowser/#/R-RNO-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Rattus norvegicus 6705 R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 6705 R-SSC-9756134 https://reactome.org/PathwayBrowser/#/R-SSC-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Sus scrofa 6705 R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 6705 R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 6737 R-BTA-1655879 https://reactome.org/PathwayBrowser/#/R-BTA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Bos taurus 6737 R-BTA-176059 https://reactome.org/PathwayBrowser/#/R-BTA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Bos taurus 6737 R-BTA-2161660 https://reactome.org/PathwayBrowser/#/R-BTA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Bos taurus 6737 R-BTA-3301943 https://reactome.org/PathwayBrowser/#/R-BTA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Bos taurus 6737 R-BTA-3323013 https://reactome.org/PathwayBrowser/#/R-BTA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 6737 R-BTA-3323079 https://reactome.org/PathwayBrowser/#/R-BTA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 6737 R-BTA-3341397 https://reactome.org/PathwayBrowser/#/R-BTA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 6737 R-BTA-5693724 https://reactome.org/PathwayBrowser/#/R-BTA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Bos taurus 6737 R-BTA-6799695 https://reactome.org/PathwayBrowser/#/R-BTA-6799695 GPX5,6 reduce H2O2 to H2O IEA Bos taurus 6737 R-BTA-8943279 https://reactome.org/PathwayBrowser/#/R-BTA-8943279 GGT dimers hydrolyse GSH IEA Bos taurus 6737 R-BTA-9011595 https://reactome.org/PathwayBrowser/#/R-BTA-9011595 GSTZ1 dimer dehalogenates DCA IEA Bos taurus 6737 R-CEL-3301943 https://reactome.org/PathwayBrowser/#/R-CEL-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Caenorhabditis elegans 6737 R-CEL-3323079 https://reactome.org/PathwayBrowser/#/R-CEL-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 6737 R-CEL-3341397 https://reactome.org/PathwayBrowser/#/R-CEL-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 6737 R-CEL-5693724 https://reactome.org/PathwayBrowser/#/R-CEL-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Caenorhabditis elegans 6737 R-CEL-6799695 https://reactome.org/PathwayBrowser/#/R-CEL-6799695 GPX5,6 reduce H2O2 to H2O IEA Caenorhabditis elegans 6737 R-CEL-8943279 https://reactome.org/PathwayBrowser/#/R-CEL-8943279 GGT dimers hydrolyse GSH IEA Caenorhabditis elegans 6737 R-CEL-9011595 https://reactome.org/PathwayBrowser/#/R-CEL-9011595 GSTZ1 dimer dehalogenates DCA IEA Caenorhabditis elegans 6737 R-CFA-1655879 https://reactome.org/PathwayBrowser/#/R-CFA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Canis familiaris 6737 R-CFA-176059 https://reactome.org/PathwayBrowser/#/R-CFA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Canis familiaris 6737 R-CFA-2161660 https://reactome.org/PathwayBrowser/#/R-CFA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Canis familiaris 6737 R-CFA-3301943 https://reactome.org/PathwayBrowser/#/R-CFA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Canis familiaris 6737 R-CFA-3323013 https://reactome.org/PathwayBrowser/#/R-CFA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 6737 R-CFA-3323079 https://reactome.org/PathwayBrowser/#/R-CFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 6737 R-CFA-5693724 https://reactome.org/PathwayBrowser/#/R-CFA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Canis familiaris 6737 R-CFA-6799695 https://reactome.org/PathwayBrowser/#/R-CFA-6799695 GPX5,6 reduce H2O2 to H2O IEA Canis familiaris 6737 R-CFA-8943279 https://reactome.org/PathwayBrowser/#/R-CFA-8943279 GGT dimers hydrolyse GSH IEA Canis familiaris 6737 R-CFA-9011595 https://reactome.org/PathwayBrowser/#/R-CFA-9011595 GSTZ1 dimer dehalogenates DCA IEA Canis familiaris 6737 R-DDI-176059 https://reactome.org/PathwayBrowser/#/R-DDI-176059 GST trimers transfer GS from GSH to luminal substrates IEA Dictyostelium discoideum 6737 R-DDI-3323079 https://reactome.org/PathwayBrowser/#/R-DDI-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 6737 R-DDI-5693724 https://reactome.org/PathwayBrowser/#/R-DDI-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Dictyostelium discoideum 6737 R-DDI-9011595 https://reactome.org/PathwayBrowser/#/R-DDI-9011595 GSTZ1 dimer dehalogenates DCA IEA Dictyostelium discoideum 6737 R-DME-176059 https://reactome.org/PathwayBrowser/#/R-DME-176059 GST trimers transfer GS from GSH to luminal substrates IEA Drosophila melanogaster 6737 R-DME-2161660 https://reactome.org/PathwayBrowser/#/R-DME-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Drosophila melanogaster 6737 R-DME-5693724 https://reactome.org/PathwayBrowser/#/R-DME-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Drosophila melanogaster 6737 R-DME-8943279 https://reactome.org/PathwayBrowser/#/R-DME-8943279 GGT dimers hydrolyse GSH IEA Drosophila melanogaster 6737 R-DME-9011595 https://reactome.org/PathwayBrowser/#/R-DME-9011595 GSTZ1 dimer dehalogenates DCA IEA Drosophila melanogaster 6737 R-DRE-176059 https://reactome.org/PathwayBrowser/#/R-DRE-176059 GST trimers transfer GS from GSH to luminal substrates IEA Danio rerio 6737 R-DRE-2161660 https://reactome.org/PathwayBrowser/#/R-DRE-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Danio rerio 6737 R-DRE-3301943 https://reactome.org/PathwayBrowser/#/R-DRE-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Danio rerio 6737 R-DRE-5693724 https://reactome.org/PathwayBrowser/#/R-DRE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Danio rerio 6737 R-DRE-6799695 https://reactome.org/PathwayBrowser/#/R-DRE-6799695 GPX5,6 reduce H2O2 to H2O IEA Danio rerio 6737 R-DRE-9011595 https://reactome.org/PathwayBrowser/#/R-DRE-9011595 GSTZ1 dimer dehalogenates DCA IEA Danio rerio 6737 R-GGA-176059 https://reactome.org/PathwayBrowser/#/R-GGA-176059 GST trimers transfer GS from GSH to luminal substrates IEA Gallus gallus 6737 R-GGA-2161660 https://reactome.org/PathwayBrowser/#/R-GGA-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Gallus gallus 6737 R-GGA-3301943 https://reactome.org/PathwayBrowser/#/R-GGA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Gallus gallus 6737 R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 6737 R-GGA-3341397 https://reactome.org/PathwayBrowser/#/R-GGA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 6737 R-GGA-5693724 https://reactome.org/PathwayBrowser/#/R-GGA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Gallus gallus 6737 R-GGA-8943279 https://reactome.org/PathwayBrowser/#/R-GGA-8943279 GGT dimers hydrolyse GSH IEA Gallus gallus 6737 R-GGA-9011595 https://reactome.org/PathwayBrowser/#/R-GGA-9011595 GSTZ1 dimer dehalogenates DCA IEA Gallus gallus 6737 R-HSA-1247915 https://reactome.org/PathwayBrowser/#/R-HSA-1247915 GSH translocates from cytosol to extracellular region TAS Homo sapiens 6737 R-HSA-1500817 https://reactome.org/PathwayBrowser/#/R-HSA-1500817 Glutathione is taken up by the bacterium TAS Homo sapiens 6737 R-HSA-1655879 https://reactome.org/PathwayBrowser/#/R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione TAS Homo sapiens 6737 R-HSA-176059 https://reactome.org/PathwayBrowser/#/R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates TAS Homo sapiens 6737 R-HSA-2161660 https://reactome.org/PathwayBrowser/#/R-HSA-2161660 PGH2 is isomerised to PGE2 by PTGES TAS Homo sapiens 6737 R-HSA-3301943 https://reactome.org/PathwayBrowser/#/R-HSA-3301943 GSTK1 dimer transfers GS from GSH to CDNB TAS Homo sapiens 6737 R-HSA-3323013 https://reactome.org/PathwayBrowser/#/R-HSA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 6737 R-HSA-3323079 https://reactome.org/PathwayBrowser/#/R-HSA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 6737 R-HSA-3341397 https://reactome.org/PathwayBrowser/#/R-HSA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 6737 R-HSA-5693724 https://reactome.org/PathwayBrowser/#/R-HSA-5693724 ESD dimer hydrolyses S-FGSH to GSH TAS Homo sapiens 6737 R-HSA-6799695 https://reactome.org/PathwayBrowser/#/R-HSA-6799695 GPX5,6 reduce H2O2 to H2O TAS Homo sapiens 6737 R-HSA-8943279 https://reactome.org/PathwayBrowser/#/R-HSA-8943279 GGT dimers hydrolyse GSH TAS Homo sapiens 6737 R-HSA-9011595 https://reactome.org/PathwayBrowser/#/R-HSA-9011595 GSTZ1 dimer dehalogenates DCA TAS Homo sapiens 6737 R-HSA-9035966 https://reactome.org/PathwayBrowser/#/R-HSA-9035966 Defective GGT1 does not hydrolyse GSH TAS Homo sapiens 6737 R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 6737 R-MMU-1655879 https://reactome.org/PathwayBrowser/#/R-MMU-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Mus musculus 6737 R-MMU-176059 https://reactome.org/PathwayBrowser/#/R-MMU-176059 GST trimers transfer GS from GSH to luminal substrates IEA Mus musculus 6737 R-MMU-2161660 https://reactome.org/PathwayBrowser/#/R-MMU-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Mus musculus 6737 R-MMU-3301943 https://reactome.org/PathwayBrowser/#/R-MMU-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Mus musculus 6737 R-MMU-3323013 https://reactome.org/PathwayBrowser/#/R-MMU-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 6737 R-MMU-3323079 https://reactome.org/PathwayBrowser/#/R-MMU-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 6737 R-MMU-3341397 https://reactome.org/PathwayBrowser/#/R-MMU-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 6737 R-MMU-5693724 https://reactome.org/PathwayBrowser/#/R-MMU-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Mus musculus 6737 R-MMU-6799695 https://reactome.org/PathwayBrowser/#/R-MMU-6799695 GPX5,6 reduce H2O2 to H2O IEA Mus musculus 6737 R-MMU-8943279 https://reactome.org/PathwayBrowser/#/R-MMU-8943279 GGT dimers hydrolyse GSH IEA Mus musculus 6737 R-MMU-9011595 https://reactome.org/PathwayBrowser/#/R-MMU-9011595 GSTZ1 dimer dehalogenates DCA IEA Mus musculus 6737 R-PFA-3323079 https://reactome.org/PathwayBrowser/#/R-PFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 6737 R-RNO-1655879 https://reactome.org/PathwayBrowser/#/R-RNO-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Rattus norvegicus 6737 R-RNO-176059 https://reactome.org/PathwayBrowser/#/R-RNO-176059 GST trimers transfer GS from GSH to luminal substrates IEA Rattus norvegicus 6737 R-RNO-2161660 https://reactome.org/PathwayBrowser/#/R-RNO-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Rattus norvegicus 6737 R-RNO-3301943 https://reactome.org/PathwayBrowser/#/R-RNO-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Rattus norvegicus 6737 R-RNO-3323013 https://reactome.org/PathwayBrowser/#/R-RNO-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 6737 R-RNO-3323079 https://reactome.org/PathwayBrowser/#/R-RNO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 6737 R-RNO-3341397 https://reactome.org/PathwayBrowser/#/R-RNO-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 6737 R-RNO-5693724 https://reactome.org/PathwayBrowser/#/R-RNO-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Rattus norvegicus 6737 R-RNO-6799695 https://reactome.org/PathwayBrowser/#/R-RNO-6799695 GPX5,6 reduce H2O2 to H2O IEA Rattus norvegicus 6737 R-RNO-8943279 https://reactome.org/PathwayBrowser/#/R-RNO-8943279 GGT dimers hydrolyse GSH IEA Rattus norvegicus 6737 R-RNO-9011595 https://reactome.org/PathwayBrowser/#/R-RNO-9011595 GSTZ1 dimer dehalogenates DCA IEA Rattus norvegicus 6737 R-SCE-3323079 https://reactome.org/PathwayBrowser/#/R-SCE-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 6737 R-SCE-5693724 https://reactome.org/PathwayBrowser/#/R-SCE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Saccharomyces cerevisiae 6737 R-SCE-8943279 https://reactome.org/PathwayBrowser/#/R-SCE-8943279 GGT dimers hydrolyse GSH IEA Saccharomyces cerevisiae 6737 R-SPO-3323079 https://reactome.org/PathwayBrowser/#/R-SPO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 6737 R-SPO-8943279 https://reactome.org/PathwayBrowser/#/R-SPO-8943279 GGT dimers hydrolyse GSH IEA Schizosaccharomyces pombe 6737 R-SSC-1655879 https://reactome.org/PathwayBrowser/#/R-SSC-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Sus scrofa 6737 R-SSC-176059 https://reactome.org/PathwayBrowser/#/R-SSC-176059 GST trimers transfer GS from GSH to luminal substrates IEA Sus scrofa 6737 R-SSC-2161660 https://reactome.org/PathwayBrowser/#/R-SSC-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Sus scrofa 6737 R-SSC-3301943 https://reactome.org/PathwayBrowser/#/R-SSC-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Sus scrofa 6737 R-SSC-3323013 https://reactome.org/PathwayBrowser/#/R-SSC-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 6737 R-SSC-3323079 https://reactome.org/PathwayBrowser/#/R-SSC-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 6737 R-SSC-3341397 https://reactome.org/PathwayBrowser/#/R-SSC-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 6737 R-SSC-5693724 https://reactome.org/PathwayBrowser/#/R-SSC-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Sus scrofa 6737 R-SSC-6799695 https://reactome.org/PathwayBrowser/#/R-SSC-6799695 GPX5,6 reduce H2O2 to H2O IEA Sus scrofa 6737 R-SSC-8943279 https://reactome.org/PathwayBrowser/#/R-SSC-8943279 GGT dimers hydrolyse GSH IEA Sus scrofa 6737 R-SSC-9011595 https://reactome.org/PathwayBrowser/#/R-SSC-9011595 GSTZ1 dimer dehalogenates DCA IEA Sus scrofa 6737 R-XTR-1655879 https://reactome.org/PathwayBrowser/#/R-XTR-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Xenopus tropicalis 6737 R-XTR-176059 https://reactome.org/PathwayBrowser/#/R-XTR-176059 GST trimers transfer GS from GSH to luminal substrates IEA Xenopus tropicalis 6737 R-XTR-2161660 https://reactome.org/PathwayBrowser/#/R-XTR-2161660 PGH2 is isomerised to PGE2 by PTGES IEA Xenopus tropicalis 6737 R-XTR-3323079 https://reactome.org/PathwayBrowser/#/R-XTR-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 6737 R-XTR-5693724 https://reactome.org/PathwayBrowser/#/R-XTR-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Xenopus tropicalis 6737 R-XTR-9011595 https://reactome.org/PathwayBrowser/#/R-XTR-9011595 GSTZ1 dimer dehalogenates DCA IEA Xenopus tropicalis 6744 R-GGA-9733403 https://reactome.org/PathwayBrowser/#/R-GGA-9733403 PCSK9 binds PCSK9 inhibitors IEA Gallus gallus 6744 R-HSA-9733403 https://reactome.org/PathwayBrowser/#/R-HSA-9733403 PCSK9 binds PCSK9 inhibitors TAS Homo sapiens 6744 R-MMU-9733403 https://reactome.org/PathwayBrowser/#/R-MMU-9733403 PCSK9 binds PCSK9 inhibitors IEA Mus musculus 6744 R-RNO-9733403 https://reactome.org/PathwayBrowser/#/R-RNO-9733403 PCSK9 binds PCSK9 inhibitors IEA Rattus norvegicus 6744 R-SCE-9733403 https://reactome.org/PathwayBrowser/#/R-SCE-9733403 PCSK9 binds PCSK9 inhibitors IEA Saccharomyces cerevisiae 6744 R-SPO-9733403 https://reactome.org/PathwayBrowser/#/R-SPO-9733403 PCSK9 binds PCSK9 inhibitors IEA Schizosaccharomyces pombe 6744 R-SSC-9733403 https://reactome.org/PathwayBrowser/#/R-SSC-9733403 PCSK9 binds PCSK9 inhibitors IEA Sus scrofa 6744 R-XTR-9733403 https://reactome.org/PathwayBrowser/#/R-XTR-9733403 PCSK9 binds PCSK9 inhibitors IEA Xenopus tropicalis 6771 R-BTA-9679477 https://reactome.org/PathwayBrowser/#/R-BTA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Bos taurus 6771 R-BTA-9691215 https://reactome.org/PathwayBrowser/#/R-BTA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Bos taurus 6771 R-CFA-9679477 https://reactome.org/PathwayBrowser/#/R-CFA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Canis familiaris 6771 R-CFA-9691215 https://reactome.org/PathwayBrowser/#/R-CFA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Canis familiaris 6771 R-DRE-9679477 https://reactome.org/PathwayBrowser/#/R-DRE-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Danio rerio 6771 R-DRE-9691215 https://reactome.org/PathwayBrowser/#/R-DRE-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Danio rerio 6771 R-GGA-9679477 https://reactome.org/PathwayBrowser/#/R-GGA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Gallus gallus 6771 R-GGA-9691215 https://reactome.org/PathwayBrowser/#/R-GGA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Gallus gallus 6771 R-HSA-9679477 https://reactome.org/PathwayBrowser/#/R-HSA-9679477 VEGFA-165 dimer binds VEGFA inhibitors TAS Homo sapiens 6771 R-HSA-9691215 https://reactome.org/PathwayBrowser/#/R-HSA-9691215 VEGFA-165 dimer binds VEGFR2 dimer TAS Homo sapiens 6771 R-MMU-9679477 https://reactome.org/PathwayBrowser/#/R-MMU-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Mus musculus 6771 R-MMU-9691215 https://reactome.org/PathwayBrowser/#/R-MMU-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Mus musculus 6771 R-RNO-9679477 https://reactome.org/PathwayBrowser/#/R-RNO-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Rattus norvegicus 6771 R-RNO-9691215 https://reactome.org/PathwayBrowser/#/R-RNO-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Rattus norvegicus 6771 R-SSC-9679477 https://reactome.org/PathwayBrowser/#/R-SSC-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Sus scrofa 6771 R-SSC-9691215 https://reactome.org/PathwayBrowser/#/R-SSC-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Sus scrofa 6771 R-XTR-9679477 https://reactome.org/PathwayBrowser/#/R-XTR-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Xenopus tropicalis 6771 R-XTR-9691215 https://reactome.org/PathwayBrowser/#/R-XTR-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Xenopus tropicalis 6774 R-BTA-9714924 https://reactome.org/PathwayBrowser/#/R-BTA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Bos taurus 6774 R-BTA-9714959 https://reactome.org/PathwayBrowser/#/R-BTA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Bos taurus 6774 R-CFA-9714924 https://reactome.org/PathwayBrowser/#/R-CFA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Canis familiaris 6774 R-CFA-9714959 https://reactome.org/PathwayBrowser/#/R-CFA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Canis familiaris 6774 R-DRE-9714924 https://reactome.org/PathwayBrowser/#/R-DRE-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Danio rerio 6774 R-DRE-9714959 https://reactome.org/PathwayBrowser/#/R-DRE-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Danio rerio 6774 R-HSA-9714924 https://reactome.org/PathwayBrowser/#/R-HSA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer TAS Homo sapiens 6774 R-HSA-9714959 https://reactome.org/PathwayBrowser/#/R-HSA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer TAS Homo sapiens 6774 R-MMU-9714924 https://reactome.org/PathwayBrowser/#/R-MMU-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Mus musculus 6774 R-MMU-9714959 https://reactome.org/PathwayBrowser/#/R-MMU-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Mus musculus 6774 R-RNO-9714924 https://reactome.org/PathwayBrowser/#/R-RNO-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Rattus norvegicus 6774 R-RNO-9714959 https://reactome.org/PathwayBrowser/#/R-RNO-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Rattus norvegicus 6774 R-SSC-9714924 https://reactome.org/PathwayBrowser/#/R-SSC-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Sus scrofa 6774 R-SSC-9714959 https://reactome.org/PathwayBrowser/#/R-SSC-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Sus scrofa 6774 R-XTR-9714924 https://reactome.org/PathwayBrowser/#/R-XTR-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Xenopus tropicalis 6774 R-XTR-9714959 https://reactome.org/PathwayBrowser/#/R-XTR-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Xenopus tropicalis 6776 R-BTA-9714924 https://reactome.org/PathwayBrowser/#/R-BTA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Bos taurus 6776 R-BTA-9714959 https://reactome.org/PathwayBrowser/#/R-BTA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Bos taurus 6776 R-CFA-9714924 https://reactome.org/PathwayBrowser/#/R-CFA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Canis familiaris 6776 R-CFA-9714959 https://reactome.org/PathwayBrowser/#/R-CFA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Canis familiaris 6776 R-DRE-9714924 https://reactome.org/PathwayBrowser/#/R-DRE-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Danio rerio 6776 R-DRE-9714959 https://reactome.org/PathwayBrowser/#/R-DRE-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Danio rerio 6776 R-HSA-9714924 https://reactome.org/PathwayBrowser/#/R-HSA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer TAS Homo sapiens 6776 R-HSA-9714959 https://reactome.org/PathwayBrowser/#/R-HSA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer TAS Homo sapiens 6776 R-MMU-9714924 https://reactome.org/PathwayBrowser/#/R-MMU-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Mus musculus 6776 R-MMU-9714959 https://reactome.org/PathwayBrowser/#/R-MMU-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Mus musculus 6776 R-RNO-9714924 https://reactome.org/PathwayBrowser/#/R-RNO-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Rattus norvegicus 6776 R-RNO-9714959 https://reactome.org/PathwayBrowser/#/R-RNO-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Rattus norvegicus 6776 R-SSC-9714924 https://reactome.org/PathwayBrowser/#/R-SSC-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Sus scrofa 6776 R-SSC-9714959 https://reactome.org/PathwayBrowser/#/R-SSC-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Sus scrofa 6776 R-XTR-9714924 https://reactome.org/PathwayBrowser/#/R-XTR-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Xenopus tropicalis 6776 R-XTR-9714959 https://reactome.org/PathwayBrowser/#/R-XTR-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Xenopus tropicalis 6779 R-BTA-9679477 https://reactome.org/PathwayBrowser/#/R-BTA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Bos taurus 6779 R-BTA-9691215 https://reactome.org/PathwayBrowser/#/R-BTA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Bos taurus 6779 R-CFA-9679477 https://reactome.org/PathwayBrowser/#/R-CFA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Canis familiaris 6779 R-CFA-9691215 https://reactome.org/PathwayBrowser/#/R-CFA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Canis familiaris 6779 R-DRE-9679477 https://reactome.org/PathwayBrowser/#/R-DRE-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Danio rerio 6779 R-DRE-9691215 https://reactome.org/PathwayBrowser/#/R-DRE-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Danio rerio 6779 R-GGA-9679477 https://reactome.org/PathwayBrowser/#/R-GGA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Gallus gallus 6779 R-GGA-9691215 https://reactome.org/PathwayBrowser/#/R-GGA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Gallus gallus 6779 R-HSA-9679477 https://reactome.org/PathwayBrowser/#/R-HSA-9679477 VEGFA-165 dimer binds VEGFA inhibitors TAS Homo sapiens 6779 R-HSA-9691215 https://reactome.org/PathwayBrowser/#/R-HSA-9691215 VEGFA-165 dimer binds VEGFR2 dimer TAS Homo sapiens 6779 R-MMU-9679477 https://reactome.org/PathwayBrowser/#/R-MMU-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Mus musculus 6779 R-MMU-9691215 https://reactome.org/PathwayBrowser/#/R-MMU-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Mus musculus 6779 R-RNO-9679477 https://reactome.org/PathwayBrowser/#/R-RNO-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Rattus norvegicus 6779 R-RNO-9691215 https://reactome.org/PathwayBrowser/#/R-RNO-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Rattus norvegicus 6779 R-SSC-9679477 https://reactome.org/PathwayBrowser/#/R-SSC-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Sus scrofa 6779 R-SSC-9691215 https://reactome.org/PathwayBrowser/#/R-SSC-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Sus scrofa 6779 R-XTR-9679477 https://reactome.org/PathwayBrowser/#/R-XTR-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Xenopus tropicalis 6779 R-XTR-9691215 https://reactome.org/PathwayBrowser/#/R-XTR-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Xenopus tropicalis 6782 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 6782 R-BTA-9684068 https://reactome.org/PathwayBrowser/#/R-BTA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Bos taurus 6782 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 6782 R-CFA-9684068 https://reactome.org/PathwayBrowser/#/R-CFA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Canis familiaris 6782 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 6782 R-DRE-9684068 https://reactome.org/PathwayBrowser/#/R-DRE-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Danio rerio 6782 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 6782 R-GGA-9684068 https://reactome.org/PathwayBrowser/#/R-GGA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Gallus gallus 6782 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 6782 R-HSA-9684068 https://reactome.org/PathwayBrowser/#/R-HSA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides TAS Homo sapiens 6782 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 6782 R-MMU-9684068 https://reactome.org/PathwayBrowser/#/R-MMU-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Mus musculus 6782 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 6782 R-RNO-9684068 https://reactome.org/PathwayBrowser/#/R-RNO-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Rattus norvegicus 6782 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 6782 R-SSC-9684068 https://reactome.org/PathwayBrowser/#/R-SSC-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Sus scrofa 6782 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 6782 R-XTR-9684068 https://reactome.org/PathwayBrowser/#/R-XTR-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Xenopus tropicalis 6784 R-BTA-9690461 https://reactome.org/PathwayBrowser/#/R-BTA-9690461 FKBP1A binds tacrolimus IEA Bos taurus 6784 R-CEL-9690461 https://reactome.org/PathwayBrowser/#/R-CEL-9690461 FKBP1A binds tacrolimus IEA Caenorhabditis elegans 6784 R-CFA-9690461 https://reactome.org/PathwayBrowser/#/R-CFA-9690461 FKBP1A binds tacrolimus IEA Canis familiaris 6784 R-DDI-9690461 https://reactome.org/PathwayBrowser/#/R-DDI-9690461 FKBP1A binds tacrolimus IEA Dictyostelium discoideum 6784 R-DME-9690461 https://reactome.org/PathwayBrowser/#/R-DME-9690461 FKBP1A binds tacrolimus IEA Drosophila melanogaster 6784 R-DRE-9690461 https://reactome.org/PathwayBrowser/#/R-DRE-9690461 FKBP1A binds tacrolimus IEA Danio rerio 6784 R-GGA-9690461 https://reactome.org/PathwayBrowser/#/R-GGA-9690461 FKBP1A binds tacrolimus IEA Gallus gallus 6784 R-HSA-2025882 https://reactome.org/PathwayBrowser/#/R-HSA-2025882 Calcineurin dephosphorylates NFATC1,2,3 IEA Homo sapiens 6784 R-HSA-9690461 https://reactome.org/PathwayBrowser/#/R-HSA-9690461 FKBP1A binds tacrolimus TAS Homo sapiens 6784 R-MMU-9690461 https://reactome.org/PathwayBrowser/#/R-MMU-9690461 FKBP1A binds tacrolimus IEA Mus musculus 6784 R-RNO-9690461 https://reactome.org/PathwayBrowser/#/R-RNO-9690461 FKBP1A binds tacrolimus IEA Rattus norvegicus 6784 R-SCE-9690461 https://reactome.org/PathwayBrowser/#/R-SCE-9690461 FKBP1A binds tacrolimus IEA Saccharomyces cerevisiae 6784 R-SPO-9690461 https://reactome.org/PathwayBrowser/#/R-SPO-9690461 FKBP1A binds tacrolimus IEA Schizosaccharomyces pombe 6784 R-SSC-9690461 https://reactome.org/PathwayBrowser/#/R-SSC-9690461 FKBP1A binds tacrolimus IEA Sus scrofa 6784 R-XTR-9690461 https://reactome.org/PathwayBrowser/#/R-XTR-9690461 FKBP1A binds tacrolimus IEA Xenopus tropicalis 6785 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6785 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6785 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6785 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6785 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6785 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6785 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6785 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6785 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6785 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6785 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6785 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6785 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6785 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6785 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6785 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6785 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6785 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6785 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6785 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6786 R-BTA-9679477 https://reactome.org/PathwayBrowser/#/R-BTA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Bos taurus 6786 R-BTA-9691215 https://reactome.org/PathwayBrowser/#/R-BTA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Bos taurus 6786 R-CFA-9679477 https://reactome.org/PathwayBrowser/#/R-CFA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Canis familiaris 6786 R-CFA-9691215 https://reactome.org/PathwayBrowser/#/R-CFA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Canis familiaris 6786 R-DRE-9679477 https://reactome.org/PathwayBrowser/#/R-DRE-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Danio rerio 6786 R-DRE-9691215 https://reactome.org/PathwayBrowser/#/R-DRE-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Danio rerio 6786 R-GGA-9679477 https://reactome.org/PathwayBrowser/#/R-GGA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Gallus gallus 6786 R-GGA-9691215 https://reactome.org/PathwayBrowser/#/R-GGA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Gallus gallus 6786 R-HSA-9679477 https://reactome.org/PathwayBrowser/#/R-HSA-9679477 VEGFA-165 dimer binds VEGFA inhibitors TAS Homo sapiens 6786 R-HSA-9691215 https://reactome.org/PathwayBrowser/#/R-HSA-9691215 VEGFA-165 dimer binds VEGFR2 dimer TAS Homo sapiens 6786 R-MMU-9679477 https://reactome.org/PathwayBrowser/#/R-MMU-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Mus musculus 6786 R-MMU-9691215 https://reactome.org/PathwayBrowser/#/R-MMU-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Mus musculus 6786 R-RNO-9679477 https://reactome.org/PathwayBrowser/#/R-RNO-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Rattus norvegicus 6786 R-RNO-9691215 https://reactome.org/PathwayBrowser/#/R-RNO-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Rattus norvegicus 6786 R-SSC-9679477 https://reactome.org/PathwayBrowser/#/R-SSC-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Sus scrofa 6786 R-SSC-9691215 https://reactome.org/PathwayBrowser/#/R-SSC-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Sus scrofa 6786 R-XTR-9679477 https://reactome.org/PathwayBrowser/#/R-XTR-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Xenopus tropicalis 6786 R-XTR-9691215 https://reactome.org/PathwayBrowser/#/R-XTR-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Xenopus tropicalis 6789 R-BTA-9714924 https://reactome.org/PathwayBrowser/#/R-BTA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Bos taurus 6789 R-BTA-9714959 https://reactome.org/PathwayBrowser/#/R-BTA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Bos taurus 6789 R-CFA-9714924 https://reactome.org/PathwayBrowser/#/R-CFA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Canis familiaris 6789 R-CFA-9714959 https://reactome.org/PathwayBrowser/#/R-CFA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Canis familiaris 6789 R-DRE-9714924 https://reactome.org/PathwayBrowser/#/R-DRE-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Danio rerio 6789 R-DRE-9714959 https://reactome.org/PathwayBrowser/#/R-DRE-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Danio rerio 6789 R-HSA-9714924 https://reactome.org/PathwayBrowser/#/R-HSA-9714924 TNF-alpha inhibitors bind to soluble TNF trimer TAS Homo sapiens 6789 R-HSA-9714959 https://reactome.org/PathwayBrowser/#/R-HSA-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer TAS Homo sapiens 6789 R-MMU-9714924 https://reactome.org/PathwayBrowser/#/R-MMU-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Mus musculus 6789 R-MMU-9714959 https://reactome.org/PathwayBrowser/#/R-MMU-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Mus musculus 6789 R-RNO-9714924 https://reactome.org/PathwayBrowser/#/R-RNO-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Rattus norvegicus 6789 R-RNO-9714959 https://reactome.org/PathwayBrowser/#/R-RNO-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Rattus norvegicus 6789 R-SSC-9714924 https://reactome.org/PathwayBrowser/#/R-SSC-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Sus scrofa 6789 R-SSC-9714959 https://reactome.org/PathwayBrowser/#/R-SSC-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Sus scrofa 6789 R-XTR-9714924 https://reactome.org/PathwayBrowser/#/R-XTR-9714924 TNF-alpha inhibitors bind to soluble TNF trimer IEA Xenopus tropicalis 6789 R-XTR-9714959 https://reactome.org/PathwayBrowser/#/R-XTR-9714959 TNF-alpha inhibitors bind to TNF(1-233) trimer IEA Xenopus tropicalis 6792 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 6792 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 6792 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 6792 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 6792 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 6792 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 6792 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 6792 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 6792 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 6792 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 6792 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 6792 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 6794 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 6794 R-BTA-9684068 https://reactome.org/PathwayBrowser/#/R-BTA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Bos taurus 6794 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 6794 R-CFA-9684068 https://reactome.org/PathwayBrowser/#/R-CFA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Canis familiaris 6794 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 6794 R-DRE-9684068 https://reactome.org/PathwayBrowser/#/R-DRE-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Danio rerio 6794 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 6794 R-GGA-9684068 https://reactome.org/PathwayBrowser/#/R-GGA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Gallus gallus 6794 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 6794 R-HSA-9684068 https://reactome.org/PathwayBrowser/#/R-HSA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides TAS Homo sapiens 6794 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 6794 R-MMU-9684068 https://reactome.org/PathwayBrowser/#/R-MMU-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Mus musculus 6794 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 6794 R-RNO-9684068 https://reactome.org/PathwayBrowser/#/R-RNO-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Rattus norvegicus 6794 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 6794 R-SSC-9684068 https://reactome.org/PathwayBrowser/#/R-SSC-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Sus scrofa 6794 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 6794 R-XTR-9684068 https://reactome.org/PathwayBrowser/#/R-XTR-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Xenopus tropicalis 6797 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 6797 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 6797 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 6797 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 6797 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 6797 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 6797 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 6797 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 6797 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 6797 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 6797 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 6797 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 6800 R-ECO-9750081 https://reactome.org/PathwayBrowser/#/R-ECO-9750081 Carmustine produces interstrand crosslinks in E. coli DNA TAS Escherichia coli 6800 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 6801 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 6801 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 6801 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 6801 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 6801 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 6801 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 6801 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 6801 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 6801 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 6803 R-BTA-140791 https://reactome.org/PathwayBrowser/#/R-BTA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Bos taurus 6803 R-BTA-140806 https://reactome.org/PathwayBrowser/#/R-BTA-140806 SERPINC1 binds SERPINC1 activators IEA Bos taurus 6803 R-BTA-140870 https://reactome.org/PathwayBrowser/#/R-BTA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Bos taurus 6803 R-BTA-140872 https://reactome.org/PathwayBrowser/#/R-BTA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Bos taurus 6803 R-CEL-140806 https://reactome.org/PathwayBrowser/#/R-CEL-140806 SERPINC1 binds SERPINC1 activators IEA Caenorhabditis elegans 6803 R-CFA-140791 https://reactome.org/PathwayBrowser/#/R-CFA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Canis familiaris 6803 R-CFA-140806 https://reactome.org/PathwayBrowser/#/R-CFA-140806 SERPINC1 binds SERPINC1 activators IEA Canis familiaris 6803 R-CFA-140870 https://reactome.org/PathwayBrowser/#/R-CFA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Canis familiaris 6803 R-CFA-140872 https://reactome.org/PathwayBrowser/#/R-CFA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Canis familiaris 6803 R-DME-140806 https://reactome.org/PathwayBrowser/#/R-DME-140806 SERPINC1 binds SERPINC1 activators IEA Drosophila melanogaster 6803 R-DRE-140806 https://reactome.org/PathwayBrowser/#/R-DRE-140806 SERPINC1 binds SERPINC1 activators IEA Danio rerio 6803 R-GGA-140791 https://reactome.org/PathwayBrowser/#/R-GGA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Gallus gallus 6803 R-GGA-140806 https://reactome.org/PathwayBrowser/#/R-GGA-140806 SERPINC1 binds SERPINC1 activators IEA Gallus gallus 6803 R-GGA-140870 https://reactome.org/PathwayBrowser/#/R-GGA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Gallus gallus 6803 R-GGA-140872 https://reactome.org/PathwayBrowser/#/R-GGA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Gallus gallus 6803 R-HSA-140791 https://reactome.org/PathwayBrowser/#/R-HSA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin TAS Homo sapiens 6803 R-HSA-140806 https://reactome.org/PathwayBrowser/#/R-HSA-140806 SERPINC1 binds SERPINC1 activators TAS Homo sapiens 6803 R-HSA-140870 https://reactome.org/PathwayBrowser/#/R-HSA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin TAS Homo sapiens 6803 R-HSA-140872 https://reactome.org/PathwayBrowser/#/R-HSA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators TAS Homo sapiens 6803 R-MMU-140791 https://reactome.org/PathwayBrowser/#/R-MMU-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Mus musculus 6803 R-MMU-140806 https://reactome.org/PathwayBrowser/#/R-MMU-140806 SERPINC1 binds SERPINC1 activators IEA Mus musculus 6803 R-MMU-140870 https://reactome.org/PathwayBrowser/#/R-MMU-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Mus musculus 6803 R-MMU-140872 https://reactome.org/PathwayBrowser/#/R-MMU-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Mus musculus 6803 R-RNO-140791 https://reactome.org/PathwayBrowser/#/R-RNO-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Rattus norvegicus 6803 R-RNO-140806 https://reactome.org/PathwayBrowser/#/R-RNO-140806 SERPINC1 binds SERPINC1 activators IEA Rattus norvegicus 6803 R-RNO-140870 https://reactome.org/PathwayBrowser/#/R-RNO-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Rattus norvegicus 6803 R-RNO-140872 https://reactome.org/PathwayBrowser/#/R-RNO-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Rattus norvegicus 6803 R-SSC-140791 https://reactome.org/PathwayBrowser/#/R-SSC-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Sus scrofa 6803 R-SSC-140806 https://reactome.org/PathwayBrowser/#/R-SSC-140806 SERPINC1 binds SERPINC1 activators IEA Sus scrofa 6803 R-SSC-140870 https://reactome.org/PathwayBrowser/#/R-SSC-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Sus scrofa 6803 R-SSC-140872 https://reactome.org/PathwayBrowser/#/R-SSC-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Sus scrofa 6803 R-XTR-140791 https://reactome.org/PathwayBrowser/#/R-XTR-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Xenopus tropicalis 6803 R-XTR-140806 https://reactome.org/PathwayBrowser/#/R-XTR-140806 SERPINC1 binds SERPINC1 activators IEA Xenopus tropicalis 6803 R-XTR-140870 https://reactome.org/PathwayBrowser/#/R-XTR-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Xenopus tropicalis 6803 R-XTR-140872 https://reactome.org/PathwayBrowser/#/R-XTR-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Xenopus tropicalis 6804 R-BTA-140791 https://reactome.org/PathwayBrowser/#/R-BTA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Bos taurus 6804 R-BTA-140806 https://reactome.org/PathwayBrowser/#/R-BTA-140806 SERPINC1 binds SERPINC1 activators IEA Bos taurus 6804 R-BTA-140870 https://reactome.org/PathwayBrowser/#/R-BTA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Bos taurus 6804 R-BTA-140872 https://reactome.org/PathwayBrowser/#/R-BTA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Bos taurus 6804 R-CEL-140806 https://reactome.org/PathwayBrowser/#/R-CEL-140806 SERPINC1 binds SERPINC1 activators IEA Caenorhabditis elegans 6804 R-CFA-140791 https://reactome.org/PathwayBrowser/#/R-CFA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Canis familiaris 6804 R-CFA-140806 https://reactome.org/PathwayBrowser/#/R-CFA-140806 SERPINC1 binds SERPINC1 activators IEA Canis familiaris 6804 R-CFA-140870 https://reactome.org/PathwayBrowser/#/R-CFA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Canis familiaris 6804 R-CFA-140872 https://reactome.org/PathwayBrowser/#/R-CFA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Canis familiaris 6804 R-DME-140806 https://reactome.org/PathwayBrowser/#/R-DME-140806 SERPINC1 binds SERPINC1 activators IEA Drosophila melanogaster 6804 R-DRE-140806 https://reactome.org/PathwayBrowser/#/R-DRE-140806 SERPINC1 binds SERPINC1 activators IEA Danio rerio 6804 R-GGA-140791 https://reactome.org/PathwayBrowser/#/R-GGA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Gallus gallus 6804 R-GGA-140806 https://reactome.org/PathwayBrowser/#/R-GGA-140806 SERPINC1 binds SERPINC1 activators IEA Gallus gallus 6804 R-GGA-140870 https://reactome.org/PathwayBrowser/#/R-GGA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Gallus gallus 6804 R-GGA-140872 https://reactome.org/PathwayBrowser/#/R-GGA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Gallus gallus 6804 R-HSA-140791 https://reactome.org/PathwayBrowser/#/R-HSA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin TAS Homo sapiens 6804 R-HSA-140806 https://reactome.org/PathwayBrowser/#/R-HSA-140806 SERPINC1 binds SERPINC1 activators TAS Homo sapiens 6804 R-HSA-140870 https://reactome.org/PathwayBrowser/#/R-HSA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin TAS Homo sapiens 6804 R-HSA-140872 https://reactome.org/PathwayBrowser/#/R-HSA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators TAS Homo sapiens 6804 R-MMU-140791 https://reactome.org/PathwayBrowser/#/R-MMU-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Mus musculus 6804 R-MMU-140806 https://reactome.org/PathwayBrowser/#/R-MMU-140806 SERPINC1 binds SERPINC1 activators IEA Mus musculus 6804 R-MMU-140870 https://reactome.org/PathwayBrowser/#/R-MMU-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Mus musculus 6804 R-MMU-140872 https://reactome.org/PathwayBrowser/#/R-MMU-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Mus musculus 6804 R-RNO-140791 https://reactome.org/PathwayBrowser/#/R-RNO-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Rattus norvegicus 6804 R-RNO-140806 https://reactome.org/PathwayBrowser/#/R-RNO-140806 SERPINC1 binds SERPINC1 activators IEA Rattus norvegicus 6804 R-RNO-140870 https://reactome.org/PathwayBrowser/#/R-RNO-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Rattus norvegicus 6804 R-RNO-140872 https://reactome.org/PathwayBrowser/#/R-RNO-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Rattus norvegicus 6804 R-SSC-140791 https://reactome.org/PathwayBrowser/#/R-SSC-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Sus scrofa 6804 R-SSC-140806 https://reactome.org/PathwayBrowser/#/R-SSC-140806 SERPINC1 binds SERPINC1 activators IEA Sus scrofa 6804 R-SSC-140870 https://reactome.org/PathwayBrowser/#/R-SSC-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Sus scrofa 6804 R-SSC-140872 https://reactome.org/PathwayBrowser/#/R-SSC-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Sus scrofa 6804 R-XTR-140791 https://reactome.org/PathwayBrowser/#/R-XTR-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Xenopus tropicalis 6804 R-XTR-140806 https://reactome.org/PathwayBrowser/#/R-XTR-140806 SERPINC1 binds SERPINC1 activators IEA Xenopus tropicalis 6804 R-XTR-140870 https://reactome.org/PathwayBrowser/#/R-XTR-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Xenopus tropicalis 6804 R-XTR-140872 https://reactome.org/PathwayBrowser/#/R-XTR-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Xenopus tropicalis 6805 R-HSA-9710480 https://reactome.org/PathwayBrowser/#/R-HSA-9710480 Decitabine triphosphate incorporates into DNA TAS Homo sapiens 6805 R-HSA-9710490 https://reactome.org/PathwayBrowser/#/R-HSA-9710490 The GSDME gene promoter is hypermethylated TAS Homo sapiens 6806 R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 6806 R-BTA-9684068 https://reactome.org/PathwayBrowser/#/R-BTA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Bos taurus 6806 R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 6806 R-CFA-9684068 https://reactome.org/PathwayBrowser/#/R-CFA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Canis familiaris 6806 R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 6806 R-DRE-9684068 https://reactome.org/PathwayBrowser/#/R-DRE-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Danio rerio 6806 R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 6806 R-GGA-9684068 https://reactome.org/PathwayBrowser/#/R-GGA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Gallus gallus 6806 R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 6806 R-HSA-9684068 https://reactome.org/PathwayBrowser/#/R-HSA-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides TAS Homo sapiens 6806 R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 6806 R-MMU-9684068 https://reactome.org/PathwayBrowser/#/R-MMU-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Mus musculus 6806 R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 6806 R-RNO-9684068 https://reactome.org/PathwayBrowser/#/R-RNO-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Rattus norvegicus 6806 R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 6806 R-SSC-9684068 https://reactome.org/PathwayBrowser/#/R-SSC-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Sus scrofa 6806 R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 6806 R-XTR-9684068 https://reactome.org/PathwayBrowser/#/R-XTR-9684068 ATP1A:ATP1B:FXYD binds cardiac glycosides IEA Xenopus tropicalis 6807 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 6807 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 6807 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 6807 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 6807 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 6807 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 6807 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 6807 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 6807 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 6807 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 6807 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 6807 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 6808 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 6808 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 6808 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 6808 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 6808 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 6808 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 6808 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 6808 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 6808 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 6808 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 6808 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 6808 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 6808 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 6808 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 6808 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 6808 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 6809 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6809 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6809 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6809 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6809 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6809 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6809 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6809 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6809 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6809 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6809 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6809 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6809 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6809 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6809 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6809 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6809 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6809 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6809 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6809 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6810 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 6810 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 6810 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 6810 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 6810 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 6810 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 6810 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 6810 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 6810 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 6810 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 6810 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 6810 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 6811 R-BTA-140791 https://reactome.org/PathwayBrowser/#/R-BTA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Bos taurus 6811 R-BTA-140806 https://reactome.org/PathwayBrowser/#/R-BTA-140806 SERPINC1 binds SERPINC1 activators IEA Bos taurus 6811 R-BTA-140870 https://reactome.org/PathwayBrowser/#/R-BTA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Bos taurus 6811 R-BTA-140872 https://reactome.org/PathwayBrowser/#/R-BTA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Bos taurus 6811 R-CEL-140806 https://reactome.org/PathwayBrowser/#/R-CEL-140806 SERPINC1 binds SERPINC1 activators IEA Caenorhabditis elegans 6811 R-CFA-140791 https://reactome.org/PathwayBrowser/#/R-CFA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Canis familiaris 6811 R-CFA-140806 https://reactome.org/PathwayBrowser/#/R-CFA-140806 SERPINC1 binds SERPINC1 activators IEA Canis familiaris 6811 R-CFA-140870 https://reactome.org/PathwayBrowser/#/R-CFA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Canis familiaris 6811 R-CFA-140872 https://reactome.org/PathwayBrowser/#/R-CFA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Canis familiaris 6811 R-DME-140806 https://reactome.org/PathwayBrowser/#/R-DME-140806 SERPINC1 binds SERPINC1 activators IEA Drosophila melanogaster 6811 R-DRE-140806 https://reactome.org/PathwayBrowser/#/R-DRE-140806 SERPINC1 binds SERPINC1 activators IEA Danio rerio 6811 R-GGA-140791 https://reactome.org/PathwayBrowser/#/R-GGA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Gallus gallus 6811 R-GGA-140806 https://reactome.org/PathwayBrowser/#/R-GGA-140806 SERPINC1 binds SERPINC1 activators IEA Gallus gallus 6811 R-GGA-140870 https://reactome.org/PathwayBrowser/#/R-GGA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Gallus gallus 6811 R-GGA-140872 https://reactome.org/PathwayBrowser/#/R-GGA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Gallus gallus 6811 R-HSA-140791 https://reactome.org/PathwayBrowser/#/R-HSA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin TAS Homo sapiens 6811 R-HSA-140806 https://reactome.org/PathwayBrowser/#/R-HSA-140806 SERPINC1 binds SERPINC1 activators TAS Homo sapiens 6811 R-HSA-140870 https://reactome.org/PathwayBrowser/#/R-HSA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin TAS Homo sapiens 6811 R-HSA-140872 https://reactome.org/PathwayBrowser/#/R-HSA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators TAS Homo sapiens 6811 R-MMU-140791 https://reactome.org/PathwayBrowser/#/R-MMU-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Mus musculus 6811 R-MMU-140806 https://reactome.org/PathwayBrowser/#/R-MMU-140806 SERPINC1 binds SERPINC1 activators IEA Mus musculus 6811 R-MMU-140870 https://reactome.org/PathwayBrowser/#/R-MMU-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Mus musculus 6811 R-MMU-140872 https://reactome.org/PathwayBrowser/#/R-MMU-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Mus musculus 6811 R-RNO-140791 https://reactome.org/PathwayBrowser/#/R-RNO-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Rattus norvegicus 6811 R-RNO-140806 https://reactome.org/PathwayBrowser/#/R-RNO-140806 SERPINC1 binds SERPINC1 activators IEA Rattus norvegicus 6811 R-RNO-140870 https://reactome.org/PathwayBrowser/#/R-RNO-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Rattus norvegicus 6811 R-RNO-140872 https://reactome.org/PathwayBrowser/#/R-RNO-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Rattus norvegicus 6811 R-SSC-140791 https://reactome.org/PathwayBrowser/#/R-SSC-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Sus scrofa 6811 R-SSC-140806 https://reactome.org/PathwayBrowser/#/R-SSC-140806 SERPINC1 binds SERPINC1 activators IEA Sus scrofa 6811 R-SSC-140870 https://reactome.org/PathwayBrowser/#/R-SSC-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Sus scrofa 6811 R-SSC-140872 https://reactome.org/PathwayBrowser/#/R-SSC-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Sus scrofa 6811 R-XTR-140791 https://reactome.org/PathwayBrowser/#/R-XTR-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Xenopus tropicalis 6811 R-XTR-140806 https://reactome.org/PathwayBrowser/#/R-XTR-140806 SERPINC1 binds SERPINC1 activators IEA Xenopus tropicalis 6811 R-XTR-140870 https://reactome.org/PathwayBrowser/#/R-XTR-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Xenopus tropicalis 6811 R-XTR-140872 https://reactome.org/PathwayBrowser/#/R-XTR-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Xenopus tropicalis 6812 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 6812 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 6812 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 6812 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 6812 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 6812 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 6812 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 6812 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 6812 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 6812 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 6812 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 6814 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 6814 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 6814 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 6814 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 6814 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 6814 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 6814 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 6814 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 6814 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 6814 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 6814 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 6814 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 6815 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6815 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6815 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6815 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6815 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6815 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6815 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6815 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6815 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6815 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6815 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6815 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6815 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6815 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6815 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6815 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6815 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6815 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6815 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6815 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6816 R-BTA-265456 https://reactome.org/PathwayBrowser/#/R-BTA-265456 NPC1L1 binds ezetimibe IEA Bos taurus 6816 R-CEL-265456 https://reactome.org/PathwayBrowser/#/R-CEL-265456 NPC1L1 binds ezetimibe IEA Caenorhabditis elegans 6816 R-CFA-265456 https://reactome.org/PathwayBrowser/#/R-CFA-265456 NPC1L1 binds ezetimibe IEA Canis familiaris 6816 R-DDI-265456 https://reactome.org/PathwayBrowser/#/R-DDI-265456 NPC1L1 binds ezetimibe IEA Dictyostelium discoideum 6816 R-DME-265456 https://reactome.org/PathwayBrowser/#/R-DME-265456 NPC1L1 binds ezetimibe IEA Drosophila melanogaster 6816 R-HSA-265443 https://reactome.org/PathwayBrowser/#/R-HSA-265443 NPC1L1-mediated cholesterol uptake IEA Homo sapiens 6816 R-HSA-265456 https://reactome.org/PathwayBrowser/#/R-HSA-265456 NPC1L1 binds ezetimibe TAS Homo sapiens 6816 R-MMU-265456 https://reactome.org/PathwayBrowser/#/R-MMU-265456 NPC1L1 binds ezetimibe IEA Mus musculus 6816 R-RNO-265456 https://reactome.org/PathwayBrowser/#/R-RNO-265456 NPC1L1 binds ezetimibe IEA Rattus norvegicus 6816 R-SCE-265456 https://reactome.org/PathwayBrowser/#/R-SCE-265456 NPC1L1 binds ezetimibe IEA Saccharomyces cerevisiae 6816 R-SSC-265456 https://reactome.org/PathwayBrowser/#/R-SSC-265456 NPC1L1 binds ezetimibe IEA Sus scrofa 6818 R-BTA-9705794 https://reactome.org/PathwayBrowser/#/R-BTA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Bos taurus 6818 R-CEL-9705794 https://reactome.org/PathwayBrowser/#/R-CEL-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Caenorhabditis elegans 6818 R-CFA-9705794 https://reactome.org/PathwayBrowser/#/R-CFA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Canis familiaris 6818 R-DRE-9705794 https://reactome.org/PathwayBrowser/#/R-DRE-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Danio rerio 6818 R-GGA-9705794 https://reactome.org/PathwayBrowser/#/R-GGA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Gallus gallus 6818 R-HSA-9705794 https://reactome.org/PathwayBrowser/#/R-HSA-9705794 SRD5A2 binds SRD5A2 inhibitors TAS Homo sapiens 6818 R-MMU-9705794 https://reactome.org/PathwayBrowser/#/R-MMU-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Mus musculus 6818 R-RNO-9705794 https://reactome.org/PathwayBrowser/#/R-RNO-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Rattus norvegicus 6818 R-SPO-9705794 https://reactome.org/PathwayBrowser/#/R-SPO-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Schizosaccharomyces pombe 6818 R-SSC-9705794 https://reactome.org/PathwayBrowser/#/R-SSC-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Sus scrofa 6818 R-XTR-9705794 https://reactome.org/PathwayBrowser/#/R-XTR-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Xenopus tropicalis 6819 R-BTA-140791 https://reactome.org/PathwayBrowser/#/R-BTA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Bos taurus 6819 R-BTA-140806 https://reactome.org/PathwayBrowser/#/R-BTA-140806 SERPINC1 binds SERPINC1 activators IEA Bos taurus 6819 R-BTA-140870 https://reactome.org/PathwayBrowser/#/R-BTA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Bos taurus 6819 R-BTA-140872 https://reactome.org/PathwayBrowser/#/R-BTA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Bos taurus 6819 R-CEL-140806 https://reactome.org/PathwayBrowser/#/R-CEL-140806 SERPINC1 binds SERPINC1 activators IEA Caenorhabditis elegans 6819 R-CFA-140791 https://reactome.org/PathwayBrowser/#/R-CFA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Canis familiaris 6819 R-CFA-140806 https://reactome.org/PathwayBrowser/#/R-CFA-140806 SERPINC1 binds SERPINC1 activators IEA Canis familiaris 6819 R-CFA-140870 https://reactome.org/PathwayBrowser/#/R-CFA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Canis familiaris 6819 R-CFA-140872 https://reactome.org/PathwayBrowser/#/R-CFA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Canis familiaris 6819 R-DME-140806 https://reactome.org/PathwayBrowser/#/R-DME-140806 SERPINC1 binds SERPINC1 activators IEA Drosophila melanogaster 6819 R-DRE-140806 https://reactome.org/PathwayBrowser/#/R-DRE-140806 SERPINC1 binds SERPINC1 activators IEA Danio rerio 6819 R-GGA-140791 https://reactome.org/PathwayBrowser/#/R-GGA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Gallus gallus 6819 R-GGA-140806 https://reactome.org/PathwayBrowser/#/R-GGA-140806 SERPINC1 binds SERPINC1 activators IEA Gallus gallus 6819 R-GGA-140870 https://reactome.org/PathwayBrowser/#/R-GGA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Gallus gallus 6819 R-GGA-140872 https://reactome.org/PathwayBrowser/#/R-GGA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Gallus gallus 6819 R-HSA-140791 https://reactome.org/PathwayBrowser/#/R-HSA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin TAS Homo sapiens 6819 R-HSA-140806 https://reactome.org/PathwayBrowser/#/R-HSA-140806 SERPINC1 binds SERPINC1 activators TAS Homo sapiens 6819 R-HSA-140870 https://reactome.org/PathwayBrowser/#/R-HSA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin TAS Homo sapiens 6819 R-HSA-140872 https://reactome.org/PathwayBrowser/#/R-HSA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators TAS Homo sapiens 6819 R-MMU-140791 https://reactome.org/PathwayBrowser/#/R-MMU-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Mus musculus 6819 R-MMU-140806 https://reactome.org/PathwayBrowser/#/R-MMU-140806 SERPINC1 binds SERPINC1 activators IEA Mus musculus 6819 R-MMU-140870 https://reactome.org/PathwayBrowser/#/R-MMU-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Mus musculus 6819 R-MMU-140872 https://reactome.org/PathwayBrowser/#/R-MMU-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Mus musculus 6819 R-RNO-140791 https://reactome.org/PathwayBrowser/#/R-RNO-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Rattus norvegicus 6819 R-RNO-140806 https://reactome.org/PathwayBrowser/#/R-RNO-140806 SERPINC1 binds SERPINC1 activators IEA Rattus norvegicus 6819 R-RNO-140870 https://reactome.org/PathwayBrowser/#/R-RNO-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Rattus norvegicus 6819 R-RNO-140872 https://reactome.org/PathwayBrowser/#/R-RNO-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Rattus norvegicus 6819 R-SSC-140791 https://reactome.org/PathwayBrowser/#/R-SSC-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Sus scrofa 6819 R-SSC-140806 https://reactome.org/PathwayBrowser/#/R-SSC-140806 SERPINC1 binds SERPINC1 activators IEA Sus scrofa 6819 R-SSC-140870 https://reactome.org/PathwayBrowser/#/R-SSC-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Sus scrofa 6819 R-SSC-140872 https://reactome.org/PathwayBrowser/#/R-SSC-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Sus scrofa 6819 R-XTR-140791 https://reactome.org/PathwayBrowser/#/R-XTR-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Xenopus tropicalis 6819 R-XTR-140806 https://reactome.org/PathwayBrowser/#/R-XTR-140806 SERPINC1 binds SERPINC1 activators IEA Xenopus tropicalis 6819 R-XTR-140870 https://reactome.org/PathwayBrowser/#/R-XTR-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Xenopus tropicalis 6819 R-XTR-140872 https://reactome.org/PathwayBrowser/#/R-XTR-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Xenopus tropicalis 6820 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 6820 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 6820 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 6820 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 6820 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 6820 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 6820 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 6820 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 6820 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 6821 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 6821 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 6821 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 6821 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 6821 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 6821 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 6821 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 6821 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 6821 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 6823 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6823 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6823 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6823 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6823 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6823 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6823 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6823 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6823 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6823 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6823 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6823 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6823 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6823 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6823 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6823 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6823 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6823 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6823 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6823 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6825 R-BTA-9708759 https://reactome.org/PathwayBrowser/#/R-BTA-9708759 DHODH:FMN binds DHODH inhibitors IEA Bos taurus 6825 R-CEL-9708759 https://reactome.org/PathwayBrowser/#/R-CEL-9708759 DHODH:FMN binds DHODH inhibitors IEA Caenorhabditis elegans 6825 R-CFA-9708759 https://reactome.org/PathwayBrowser/#/R-CFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Canis familiaris 6825 R-DME-9708759 https://reactome.org/PathwayBrowser/#/R-DME-9708759 DHODH:FMN binds DHODH inhibitors IEA Drosophila melanogaster 6825 R-DRE-9708759 https://reactome.org/PathwayBrowser/#/R-DRE-9708759 DHODH:FMN binds DHODH inhibitors IEA Danio rerio 6825 R-GGA-9708759 https://reactome.org/PathwayBrowser/#/R-GGA-9708759 DHODH:FMN binds DHODH inhibitors IEA Gallus gallus 6825 R-HSA-9708759 https://reactome.org/PathwayBrowser/#/R-HSA-9708759 DHODH:FMN binds DHODH inhibitors TAS Homo sapiens 6825 R-MMU-9708759 https://reactome.org/PathwayBrowser/#/R-MMU-9708759 DHODH:FMN binds DHODH inhibitors IEA Mus musculus 6825 R-PFA-9708759 https://reactome.org/PathwayBrowser/#/R-PFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Plasmodium falciparum 6825 R-RNO-9708759 https://reactome.org/PathwayBrowser/#/R-RNO-9708759 DHODH:FMN binds DHODH inhibitors IEA Rattus norvegicus 6825 R-SPO-9708759 https://reactome.org/PathwayBrowser/#/R-SPO-9708759 DHODH:FMN binds DHODH inhibitors IEA Schizosaccharomyces pombe 6825 R-SSC-9708759 https://reactome.org/PathwayBrowser/#/R-SSC-9708759 DHODH:FMN binds DHODH inhibitors IEA Sus scrofa 6825 R-XTR-9708759 https://reactome.org/PathwayBrowser/#/R-XTR-9708759 DHODH:FMN binds DHODH inhibitors IEA Xenopus tropicalis 6828 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 6828 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 6828 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 6828 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 6828 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 6828 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 6828 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 6828 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 6828 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 6828 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 6828 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 6828 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 6829 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 6829 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 6829 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 6829 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 6829 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 6829 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 6829 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 6829 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 6829 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 6829 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 6829 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 6829 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 6832 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 6832 R-BTA-9678749 https://reactome.org/PathwayBrowser/#/R-BTA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Bos taurus 6832 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 6832 R-CEL-9678749 https://reactome.org/PathwayBrowser/#/R-CEL-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Caenorhabditis elegans 6832 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 6832 R-CFA-9678749 https://reactome.org/PathwayBrowser/#/R-CFA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Canis familiaris 6832 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 6832 R-DDI-9678749 https://reactome.org/PathwayBrowser/#/R-DDI-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Dictyostelium discoideum 6832 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 6832 R-DME-9678749 https://reactome.org/PathwayBrowser/#/R-DME-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Drosophila melanogaster 6832 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 6832 R-DRE-9678749 https://reactome.org/PathwayBrowser/#/R-DRE-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Danio rerio 6832 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 6832 R-GGA-9678749 https://reactome.org/PathwayBrowser/#/R-GGA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Gallus gallus 6832 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 6832 R-HSA-9678749 https://reactome.org/PathwayBrowser/#/R-HSA-9678749 IMPDH tetramers binds IMPDH inhibitors TAS Homo sapiens 6832 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 6832 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 6832 R-MMU-9678749 https://reactome.org/PathwayBrowser/#/R-MMU-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Mus musculus 6832 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 6832 R-PFA-9678749 https://reactome.org/PathwayBrowser/#/R-PFA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Plasmodium falciparum 6832 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 6832 R-RNO-9678749 https://reactome.org/PathwayBrowser/#/R-RNO-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Rattus norvegicus 6832 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 6832 R-SCE-9678749 https://reactome.org/PathwayBrowser/#/R-SCE-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Saccharomyces cerevisiae 6832 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 6832 R-SPO-9678749 https://reactome.org/PathwayBrowser/#/R-SPO-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Schizosaccharomyces pombe 6832 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 6832 R-SSC-9678749 https://reactome.org/PathwayBrowser/#/R-SSC-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Sus scrofa 6832 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 6832 R-XTR-9678749 https://reactome.org/PathwayBrowser/#/R-XTR-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Xenopus tropicalis 6833 R-BTA-9650858 https://reactome.org/PathwayBrowser/#/R-BTA-9650858 Meglitinides bind ABCC8 IEA Bos taurus 6833 R-CFA-9650858 https://reactome.org/PathwayBrowser/#/R-CFA-9650858 Meglitinides bind ABCC8 IEA Canis familiaris 6833 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster 6833 R-GGA-9650858 https://reactome.org/PathwayBrowser/#/R-GGA-9650858 Meglitinides bind ABCC8 IEA Gallus gallus 6833 R-HSA-9650858 https://reactome.org/PathwayBrowser/#/R-HSA-9650858 Meglitinides bind ABCC8 TAS Homo sapiens 6833 R-MMU-9650858 https://reactome.org/PathwayBrowser/#/R-MMU-9650858 Meglitinides bind ABCC8 IEA Mus musculus 6833 R-RNO-9650858 https://reactome.org/PathwayBrowser/#/R-RNO-9650858 Meglitinides bind ABCC8 IEA Rattus norvegicus 6833 R-SSC-9650858 https://reactome.org/PathwayBrowser/#/R-SSC-9650858 Meglitinides bind ABCC8 IEA Sus scrofa 6833 R-XTR-9650858 https://reactome.org/PathwayBrowser/#/R-XTR-9650858 Meglitinides bind ABCC8 IEA Xenopus tropicalis 6834 R-BTA-71163 https://reactome.org/PathwayBrowser/#/R-BTA-71163 HPD dioxygenates HPP IEA Bos taurus 6834 R-CEL-71163 https://reactome.org/PathwayBrowser/#/R-CEL-71163 HPD dioxygenates HPP IEA Caenorhabditis elegans 6834 R-CFA-71163 https://reactome.org/PathwayBrowser/#/R-CFA-71163 HPD dioxygenates HPP IEA Canis familiaris 6834 R-DDI-71163 https://reactome.org/PathwayBrowser/#/R-DDI-71163 HPD dioxygenates HPP IEA Dictyostelium discoideum 6834 R-DME-71163 https://reactome.org/PathwayBrowser/#/R-DME-71163 HPD dioxygenates HPP IEA Drosophila melanogaster 6834 R-DRE-71163 https://reactome.org/PathwayBrowser/#/R-DRE-71163 HPD dioxygenates HPP IEA Danio rerio 6834 R-GGA-71163 https://reactome.org/PathwayBrowser/#/R-GGA-71163 HPD dioxygenates HPP IEA Gallus gallus 6834 R-HSA-71163 https://reactome.org/PathwayBrowser/#/R-HSA-71163 HPD dioxygenates HPP TAS Homo sapiens 6834 R-MMU-71163 https://reactome.org/PathwayBrowser/#/R-MMU-71163 HPD dioxygenates HPP IEA Mus musculus 6834 R-RNO-71163 https://reactome.org/PathwayBrowser/#/R-RNO-71163 HPD dioxygenates HPP IEA Rattus norvegicus 6834 R-SSC-71163 https://reactome.org/PathwayBrowser/#/R-SSC-71163 HPD dioxygenates HPP IEA Sus scrofa 6834 R-XTR-71163 https://reactome.org/PathwayBrowser/#/R-XTR-71163 HPD dioxygenates HPP IEA Xenopus tropicalis 6836 R-BTA-9679477 https://reactome.org/PathwayBrowser/#/R-BTA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Bos taurus 6836 R-BTA-9691215 https://reactome.org/PathwayBrowser/#/R-BTA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Bos taurus 6836 R-CFA-9679477 https://reactome.org/PathwayBrowser/#/R-CFA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Canis familiaris 6836 R-CFA-9691215 https://reactome.org/PathwayBrowser/#/R-CFA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Canis familiaris 6836 R-DRE-9679477 https://reactome.org/PathwayBrowser/#/R-DRE-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Danio rerio 6836 R-DRE-9691215 https://reactome.org/PathwayBrowser/#/R-DRE-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Danio rerio 6836 R-GGA-9679477 https://reactome.org/PathwayBrowser/#/R-GGA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Gallus gallus 6836 R-GGA-9691215 https://reactome.org/PathwayBrowser/#/R-GGA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Gallus gallus 6836 R-HSA-9679477 https://reactome.org/PathwayBrowser/#/R-HSA-9679477 VEGFA-165 dimer binds VEGFA inhibitors TAS Homo sapiens 6836 R-HSA-9691215 https://reactome.org/PathwayBrowser/#/R-HSA-9691215 VEGFA-165 dimer binds VEGFR2 dimer TAS Homo sapiens 6836 R-MMU-9679477 https://reactome.org/PathwayBrowser/#/R-MMU-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Mus musculus 6836 R-MMU-9691215 https://reactome.org/PathwayBrowser/#/R-MMU-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Mus musculus 6836 R-RNO-9679477 https://reactome.org/PathwayBrowser/#/R-RNO-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Rattus norvegicus 6836 R-RNO-9691215 https://reactome.org/PathwayBrowser/#/R-RNO-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Rattus norvegicus 6836 R-SSC-9679477 https://reactome.org/PathwayBrowser/#/R-SSC-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Sus scrofa 6836 R-SSC-9691215 https://reactome.org/PathwayBrowser/#/R-SSC-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Sus scrofa 6836 R-XTR-9679477 https://reactome.org/PathwayBrowser/#/R-XTR-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Xenopus tropicalis 6836 R-XTR-9691215 https://reactome.org/PathwayBrowser/#/R-XTR-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Xenopus tropicalis 6837 R-BTA-9709109 https://reactome.org/PathwayBrowser/#/R-BTA-9709109 DHFR dimer binds DHFR inhibitors IEA Bos taurus 6837 R-CEL-9709109 https://reactome.org/PathwayBrowser/#/R-CEL-9709109 DHFR dimer binds DHFR inhibitors IEA Caenorhabditis elegans 6837 R-CFA-9709109 https://reactome.org/PathwayBrowser/#/R-CFA-9709109 DHFR dimer binds DHFR inhibitors IEA Canis familiaris 6837 R-DDI-9709109 https://reactome.org/PathwayBrowser/#/R-DDI-9709109 DHFR dimer binds DHFR inhibitors IEA Dictyostelium discoideum 6837 R-DME-9709109 https://reactome.org/PathwayBrowser/#/R-DME-9709109 DHFR dimer binds DHFR inhibitors IEA Drosophila melanogaster 6837 R-DRE-9709109 https://reactome.org/PathwayBrowser/#/R-DRE-9709109 DHFR dimer binds DHFR inhibitors IEA Danio rerio 6837 R-GGA-9709109 https://reactome.org/PathwayBrowser/#/R-GGA-9709109 DHFR dimer binds DHFR inhibitors IEA Gallus gallus 6837 R-HSA-9709109 https://reactome.org/PathwayBrowser/#/R-HSA-9709109 DHFR dimer binds DHFR inhibitors TAS Homo sapiens 6837 R-MMU-9709109 https://reactome.org/PathwayBrowser/#/R-MMU-9709109 DHFR dimer binds DHFR inhibitors IEA Mus musculus 6837 R-RNO-9709109 https://reactome.org/PathwayBrowser/#/R-RNO-9709109 DHFR dimer binds DHFR inhibitors IEA Rattus norvegicus 6837 R-SCE-9709109 https://reactome.org/PathwayBrowser/#/R-SCE-9709109 DHFR dimer binds DHFR inhibitors IEA Saccharomyces cerevisiae 6837 R-SPO-9709109 https://reactome.org/PathwayBrowser/#/R-SPO-9709109 DHFR dimer binds DHFR inhibitors IEA Schizosaccharomyces pombe 6837 R-SSC-9709109 https://reactome.org/PathwayBrowser/#/R-SSC-9709109 DHFR dimer binds DHFR inhibitors IEA Sus scrofa 6838 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 6838 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 6838 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 6838 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 6838 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 6838 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 6838 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 6838 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 6838 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 6838 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 6838 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 6838 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 6838 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 6838 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 6838 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 6838 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 6839 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 6839 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 6839 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 6839 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 6839 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 6839 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 6839 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 6839 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 6839 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 6839 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 6839 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 6839 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 6839 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 6839 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 6839 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 6839 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 6840 R-BTA-9709109 https://reactome.org/PathwayBrowser/#/R-BTA-9709109 DHFR dimer binds DHFR inhibitors IEA Bos taurus 6840 R-CEL-9709109 https://reactome.org/PathwayBrowser/#/R-CEL-9709109 DHFR dimer binds DHFR inhibitors IEA Caenorhabditis elegans 6840 R-CFA-9709109 https://reactome.org/PathwayBrowser/#/R-CFA-9709109 DHFR dimer binds DHFR inhibitors IEA Canis familiaris 6840 R-DDI-9709109 https://reactome.org/PathwayBrowser/#/R-DDI-9709109 DHFR dimer binds DHFR inhibitors IEA Dictyostelium discoideum 6840 R-DME-9709109 https://reactome.org/PathwayBrowser/#/R-DME-9709109 DHFR dimer binds DHFR inhibitors IEA Drosophila melanogaster 6840 R-DRE-9709109 https://reactome.org/PathwayBrowser/#/R-DRE-9709109 DHFR dimer binds DHFR inhibitors IEA Danio rerio 6840 R-GGA-9709109 https://reactome.org/PathwayBrowser/#/R-GGA-9709109 DHFR dimer binds DHFR inhibitors IEA Gallus gallus 6840 R-HSA-9709109 https://reactome.org/PathwayBrowser/#/R-HSA-9709109 DHFR dimer binds DHFR inhibitors TAS Homo sapiens 6840 R-MMU-9709109 https://reactome.org/PathwayBrowser/#/R-MMU-9709109 DHFR dimer binds DHFR inhibitors IEA Mus musculus 6840 R-RNO-9709109 https://reactome.org/PathwayBrowser/#/R-RNO-9709109 DHFR dimer binds DHFR inhibitors IEA Rattus norvegicus 6840 R-SCE-9709109 https://reactome.org/PathwayBrowser/#/R-SCE-9709109 DHFR dimer binds DHFR inhibitors IEA Saccharomyces cerevisiae 6840 R-SPO-9709109 https://reactome.org/PathwayBrowser/#/R-SPO-9709109 DHFR dimer binds DHFR inhibitors IEA Schizosaccharomyces pombe 6840 R-SSC-9709109 https://reactome.org/PathwayBrowser/#/R-SSC-9709109 DHFR dimer binds DHFR inhibitors IEA Sus scrofa 6841 R-BTA-9650858 https://reactome.org/PathwayBrowser/#/R-BTA-9650858 Meglitinides bind ABCC8 IEA Bos taurus 6841 R-CFA-9650858 https://reactome.org/PathwayBrowser/#/R-CFA-9650858 Meglitinides bind ABCC8 IEA Canis familiaris 6841 R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster 6841 R-GGA-9650858 https://reactome.org/PathwayBrowser/#/R-GGA-9650858 Meglitinides bind ABCC8 IEA Gallus gallus 6841 R-HSA-9650858 https://reactome.org/PathwayBrowser/#/R-HSA-9650858 Meglitinides bind ABCC8 TAS Homo sapiens 6841 R-MMU-9650858 https://reactome.org/PathwayBrowser/#/R-MMU-9650858 Meglitinides bind ABCC8 IEA Mus musculus 6841 R-RNO-9650858 https://reactome.org/PathwayBrowser/#/R-RNO-9650858 Meglitinides bind ABCC8 IEA Rattus norvegicus 6841 R-SSC-9650858 https://reactome.org/PathwayBrowser/#/R-SSC-9650858 Meglitinides bind ABCC8 IEA Sus scrofa 6841 R-XTR-9650858 https://reactome.org/PathwayBrowser/#/R-XTR-9650858 Meglitinides bind ABCC8 IEA Xenopus tropicalis 6842 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 6842 R-BTA-9678749 https://reactome.org/PathwayBrowser/#/R-BTA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Bos taurus 6842 R-BTA-9754916 https://reactome.org/PathwayBrowser/#/R-BTA-9754916 NT5C2 tetramer phosphorylates RBV IEA Bos taurus 6842 R-BTA-9754929 https://reactome.org/PathwayBrowser/#/R-BTA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Bos taurus 6842 R-BTA-9754934 https://reactome.org/PathwayBrowser/#/R-BTA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Bos taurus 6842 R-BTA-9754964 https://reactome.org/PathwayBrowser/#/R-BTA-9754964 ADA deamidates RBV IEA Bos taurus 6842 R-BTA-9754974 https://reactome.org/PathwayBrowser/#/R-BTA-9754974 ADK phosphorylates RBV IEA Bos taurus 6842 R-BTA-9755015 https://reactome.org/PathwayBrowser/#/R-BTA-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Bos taurus 6842 R-BTA-9755035 https://reactome.org/PathwayBrowser/#/R-BTA-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Bos taurus 6842 R-BTA-9755044 https://reactome.org/PathwayBrowser/#/R-BTA-9755044 PNP trimer transforms RBV to T-CONH2 IEA Bos taurus 6842 R-BTA-9755078 https://reactome.org/PathwayBrowser/#/R-BTA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Bos taurus 6842 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 6842 R-CEL-9678749 https://reactome.org/PathwayBrowser/#/R-CEL-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Caenorhabditis elegans 6842 R-CEL-9754916 https://reactome.org/PathwayBrowser/#/R-CEL-9754916 NT5C2 tetramer phosphorylates RBV IEA Caenorhabditis elegans 6842 R-CEL-9754929 https://reactome.org/PathwayBrowser/#/R-CEL-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Caenorhabditis elegans 6842 R-CEL-9754934 https://reactome.org/PathwayBrowser/#/R-CEL-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 6842 R-CEL-9754964 https://reactome.org/PathwayBrowser/#/R-CEL-9754964 ADA deamidates RBV IEA Caenorhabditis elegans 6842 R-CEL-9754974 https://reactome.org/PathwayBrowser/#/R-CEL-9754974 ADK phosphorylates RBV IEA Caenorhabditis elegans 6842 R-CEL-9755015 https://reactome.org/PathwayBrowser/#/R-CEL-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Caenorhabditis elegans 6842 R-CEL-9755035 https://reactome.org/PathwayBrowser/#/R-CEL-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Caenorhabditis elegans 6842 R-CEL-9755044 https://reactome.org/PathwayBrowser/#/R-CEL-9755044 PNP trimer transforms RBV to T-CONH2 IEA Caenorhabditis elegans 6842 R-CEL-9755078 https://reactome.org/PathwayBrowser/#/R-CEL-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Caenorhabditis elegans 6842 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 6842 R-CFA-9678749 https://reactome.org/PathwayBrowser/#/R-CFA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Canis familiaris 6842 R-CFA-9754916 https://reactome.org/PathwayBrowser/#/R-CFA-9754916 NT5C2 tetramer phosphorylates RBV IEA Canis familiaris 6842 R-CFA-9754929 https://reactome.org/PathwayBrowser/#/R-CFA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Canis familiaris 6842 R-CFA-9754934 https://reactome.org/PathwayBrowser/#/R-CFA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Canis familiaris 6842 R-CFA-9754964 https://reactome.org/PathwayBrowser/#/R-CFA-9754964 ADA deamidates RBV IEA Canis familiaris 6842 R-CFA-9754974 https://reactome.org/PathwayBrowser/#/R-CFA-9754974 ADK phosphorylates RBV IEA Canis familiaris 6842 R-CFA-9755015 https://reactome.org/PathwayBrowser/#/R-CFA-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Canis familiaris 6842 R-CFA-9755035 https://reactome.org/PathwayBrowser/#/R-CFA-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Canis familiaris 6842 R-CFA-9755044 https://reactome.org/PathwayBrowser/#/R-CFA-9755044 PNP trimer transforms RBV to T-CONH2 IEA Canis familiaris 6842 R-CFA-9755078 https://reactome.org/PathwayBrowser/#/R-CFA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Canis familiaris 6842 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 6842 R-DDI-9678749 https://reactome.org/PathwayBrowser/#/R-DDI-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Dictyostelium discoideum 6842 R-DDI-9754916 https://reactome.org/PathwayBrowser/#/R-DDI-9754916 NT5C2 tetramer phosphorylates RBV IEA Dictyostelium discoideum 6842 R-DDI-9754929 https://reactome.org/PathwayBrowser/#/R-DDI-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 6842 R-DDI-9754964 https://reactome.org/PathwayBrowser/#/R-DDI-9754964 ADA deamidates RBV IEA Dictyostelium discoideum 6842 R-DDI-9754974 https://reactome.org/PathwayBrowser/#/R-DDI-9754974 ADK phosphorylates RBV IEA Dictyostelium discoideum 6842 R-DDI-9755015 https://reactome.org/PathwayBrowser/#/R-DDI-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Dictyostelium discoideum 6842 R-DDI-9755035 https://reactome.org/PathwayBrowser/#/R-DDI-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Dictyostelium discoideum 6842 R-DDI-9755078 https://reactome.org/PathwayBrowser/#/R-DDI-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Dictyostelium discoideum 6842 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 6842 R-DME-9678749 https://reactome.org/PathwayBrowser/#/R-DME-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Drosophila melanogaster 6842 R-DME-9754916 https://reactome.org/PathwayBrowser/#/R-DME-9754916 NT5C2 tetramer phosphorylates RBV IEA Drosophila melanogaster 6842 R-DME-9754929 https://reactome.org/PathwayBrowser/#/R-DME-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Drosophila melanogaster 6842 R-DME-9754934 https://reactome.org/PathwayBrowser/#/R-DME-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 6842 R-DME-9754974 https://reactome.org/PathwayBrowser/#/R-DME-9754974 ADK phosphorylates RBV IEA Drosophila melanogaster 6842 R-DME-9755015 https://reactome.org/PathwayBrowser/#/R-DME-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Drosophila melanogaster 6842 R-DME-9755035 https://reactome.org/PathwayBrowser/#/R-DME-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Drosophila melanogaster 6842 R-DME-9755044 https://reactome.org/PathwayBrowser/#/R-DME-9755044 PNP trimer transforms RBV to T-CONH2 IEA Drosophila melanogaster 6842 R-DME-9755078 https://reactome.org/PathwayBrowser/#/R-DME-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Drosophila melanogaster 6842 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 6842 R-DRE-9678749 https://reactome.org/PathwayBrowser/#/R-DRE-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Danio rerio 6842 R-DRE-9754964 https://reactome.org/PathwayBrowser/#/R-DRE-9754964 ADA deamidates RBV IEA Danio rerio 6842 R-DRE-9754974 https://reactome.org/PathwayBrowser/#/R-DRE-9754974 ADK phosphorylates RBV IEA Danio rerio 6842 R-DRE-9755015 https://reactome.org/PathwayBrowser/#/R-DRE-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Danio rerio 6842 R-DRE-9755035 https://reactome.org/PathwayBrowser/#/R-DRE-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Danio rerio 6842 R-DRE-9755044 https://reactome.org/PathwayBrowser/#/R-DRE-9755044 PNP trimer transforms RBV to T-CONH2 IEA Danio rerio 6842 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 6842 R-GGA-9678749 https://reactome.org/PathwayBrowser/#/R-GGA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Gallus gallus 6842 R-GGA-9754916 https://reactome.org/PathwayBrowser/#/R-GGA-9754916 NT5C2 tetramer phosphorylates RBV IEA Gallus gallus 6842 R-GGA-9754929 https://reactome.org/PathwayBrowser/#/R-GGA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Gallus gallus 6842 R-GGA-9754934 https://reactome.org/PathwayBrowser/#/R-GGA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Gallus gallus 6842 R-GGA-9754964 https://reactome.org/PathwayBrowser/#/R-GGA-9754964 ADA deamidates RBV IEA Gallus gallus 6842 R-GGA-9754974 https://reactome.org/PathwayBrowser/#/R-GGA-9754974 ADK phosphorylates RBV IEA Gallus gallus 6842 R-GGA-9755078 https://reactome.org/PathwayBrowser/#/R-GGA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Gallus gallus 6842 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 6842 R-HSA-9678749 https://reactome.org/PathwayBrowser/#/R-HSA-9678749 IMPDH tetramers binds IMPDH inhibitors TAS Homo sapiens 6842 R-HSA-9680836 https://reactome.org/PathwayBrowser/#/R-HSA-9680836 NS5B binds ribavirin TAS Homo sapiens 6842 R-HSA-9754916 https://reactome.org/PathwayBrowser/#/R-HSA-9754916 NT5C2 tetramer phosphorylates RBV TAS Homo sapiens 6842 R-HSA-9754929 https://reactome.org/PathwayBrowser/#/R-HSA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix TAS Homo sapiens 6842 R-HSA-9754934 https://reactome.org/PathwayBrowser/#/R-HSA-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol TAS Homo sapiens 6842 R-HSA-9754964 https://reactome.org/PathwayBrowser/#/R-HSA-9754964 ADA deamidates RBV TAS Homo sapiens 6842 R-HSA-9754974 https://reactome.org/PathwayBrowser/#/R-HSA-9754974 ADK phosphorylates RBV TAS Homo sapiens 6842 R-HSA-9755015 https://reactome.org/PathwayBrowser/#/R-HSA-9755015 SLC29A1 transports RBV from extracellular region to cytosol TAS Homo sapiens 6842 R-HSA-9755035 https://reactome.org/PathwayBrowser/#/R-HSA-9755035 SLC29A1 transports RBV from cytosol to extracellular region TAS Homo sapiens 6842 R-HSA-9755044 https://reactome.org/PathwayBrowser/#/R-HSA-9755044 PNP trimer transforms RBV to T-CONH2 TAS Homo sapiens 6842 R-HSA-9755078 https://reactome.org/PathwayBrowser/#/R-HSA-9755078 NT5C2 tetramer dephosphorylates RBV-MP TAS Homo sapiens 6842 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 6842 R-MMU-9678749 https://reactome.org/PathwayBrowser/#/R-MMU-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Mus musculus 6842 R-MMU-9754916 https://reactome.org/PathwayBrowser/#/R-MMU-9754916 NT5C2 tetramer phosphorylates RBV IEA Mus musculus 6842 R-MMU-9754929 https://reactome.org/PathwayBrowser/#/R-MMU-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Mus musculus 6842 R-MMU-9754934 https://reactome.org/PathwayBrowser/#/R-MMU-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Mus musculus 6842 R-MMU-9754964 https://reactome.org/PathwayBrowser/#/R-MMU-9754964 ADA deamidates RBV IEA Mus musculus 6842 R-MMU-9754974 https://reactome.org/PathwayBrowser/#/R-MMU-9754974 ADK phosphorylates RBV IEA Mus musculus 6842 R-MMU-9755015 https://reactome.org/PathwayBrowser/#/R-MMU-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Mus musculus 6842 R-MMU-9755035 https://reactome.org/PathwayBrowser/#/R-MMU-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Mus musculus 6842 R-MMU-9755044 https://reactome.org/PathwayBrowser/#/R-MMU-9755044 PNP trimer transforms RBV to T-CONH2 IEA Mus musculus 6842 R-MMU-9755078 https://reactome.org/PathwayBrowser/#/R-MMU-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Mus musculus 6842 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 6842 R-PFA-9678749 https://reactome.org/PathwayBrowser/#/R-PFA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Plasmodium falciparum 6842 R-PFA-9754929 https://reactome.org/PathwayBrowser/#/R-PFA-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Plasmodium falciparum 6842 R-PFA-9754964 https://reactome.org/PathwayBrowser/#/R-PFA-9754964 ADA deamidates RBV IEA Plasmodium falciparum 6842 R-PFA-9755015 https://reactome.org/PathwayBrowser/#/R-PFA-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Plasmodium falciparum 6842 R-PFA-9755035 https://reactome.org/PathwayBrowser/#/R-PFA-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Plasmodium falciparum 6842 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 6842 R-RNO-9678749 https://reactome.org/PathwayBrowser/#/R-RNO-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Rattus norvegicus 6842 R-RNO-9754916 https://reactome.org/PathwayBrowser/#/R-RNO-9754916 NT5C2 tetramer phosphorylates RBV IEA Rattus norvegicus 6842 R-RNO-9754929 https://reactome.org/PathwayBrowser/#/R-RNO-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Rattus norvegicus 6842 R-RNO-9754934 https://reactome.org/PathwayBrowser/#/R-RNO-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Rattus norvegicus 6842 R-RNO-9754964 https://reactome.org/PathwayBrowser/#/R-RNO-9754964 ADA deamidates RBV IEA Rattus norvegicus 6842 R-RNO-9754974 https://reactome.org/PathwayBrowser/#/R-RNO-9754974 ADK phosphorylates RBV IEA Rattus norvegicus 6842 R-RNO-9755015 https://reactome.org/PathwayBrowser/#/R-RNO-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Rattus norvegicus 6842 R-RNO-9755035 https://reactome.org/PathwayBrowser/#/R-RNO-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Rattus norvegicus 6842 R-RNO-9755044 https://reactome.org/PathwayBrowser/#/R-RNO-9755044 PNP trimer transforms RBV to T-CONH2 IEA Rattus norvegicus 6842 R-RNO-9755078 https://reactome.org/PathwayBrowser/#/R-RNO-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Rattus norvegicus 6842 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 6842 R-SCE-9678749 https://reactome.org/PathwayBrowser/#/R-SCE-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Saccharomyces cerevisiae 6842 R-SCE-9754974 https://reactome.org/PathwayBrowser/#/R-SCE-9754974 ADK phosphorylates RBV IEA Saccharomyces cerevisiae 6842 R-SCE-9755044 https://reactome.org/PathwayBrowser/#/R-SCE-9755044 PNP trimer transforms RBV to T-CONH2 IEA Saccharomyces cerevisiae 6842 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 6842 R-SPO-9678749 https://reactome.org/PathwayBrowser/#/R-SPO-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Schizosaccharomyces pombe 6842 R-SPO-9754974 https://reactome.org/PathwayBrowser/#/R-SPO-9754974 ADK phosphorylates RBV IEA Schizosaccharomyces pombe 6842 R-SPO-9755044 https://reactome.org/PathwayBrowser/#/R-SPO-9755044 PNP trimer transforms RBV to T-CONH2 IEA Schizosaccharomyces pombe 6842 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 6842 R-SSC-9678749 https://reactome.org/PathwayBrowser/#/R-SSC-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Sus scrofa 6842 R-SSC-9754916 https://reactome.org/PathwayBrowser/#/R-SSC-9754916 NT5C2 tetramer phosphorylates RBV IEA Sus scrofa 6842 R-SSC-9754929 https://reactome.org/PathwayBrowser/#/R-SSC-9754929 SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix IEA Sus scrofa 6842 R-SSC-9754934 https://reactome.org/PathwayBrowser/#/R-SSC-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Sus scrofa 6842 R-SSC-9754964 https://reactome.org/PathwayBrowser/#/R-SSC-9754964 ADA deamidates RBV IEA Sus scrofa 6842 R-SSC-9754974 https://reactome.org/PathwayBrowser/#/R-SSC-9754974 ADK phosphorylates RBV IEA Sus scrofa 6842 R-SSC-9755015 https://reactome.org/PathwayBrowser/#/R-SSC-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Sus scrofa 6842 R-SSC-9755035 https://reactome.org/PathwayBrowser/#/R-SSC-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Sus scrofa 6842 R-SSC-9755044 https://reactome.org/PathwayBrowser/#/R-SSC-9755044 PNP trimer transforms RBV to T-CONH2 IEA Sus scrofa 6842 R-SSC-9755078 https://reactome.org/PathwayBrowser/#/R-SSC-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Sus scrofa 6842 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 6842 R-XTR-9678749 https://reactome.org/PathwayBrowser/#/R-XTR-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Xenopus tropicalis 6842 R-XTR-9754916 https://reactome.org/PathwayBrowser/#/R-XTR-9754916 NT5C2 tetramer phosphorylates RBV IEA Xenopus tropicalis 6842 R-XTR-9754934 https://reactome.org/PathwayBrowser/#/R-XTR-9754934 SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 6842 R-XTR-9754964 https://reactome.org/PathwayBrowser/#/R-XTR-9754964 ADA deamidates RBV IEA Xenopus tropicalis 6842 R-XTR-9754974 https://reactome.org/PathwayBrowser/#/R-XTR-9754974 ADK phosphorylates RBV IEA Xenopus tropicalis 6842 R-XTR-9755015 https://reactome.org/PathwayBrowser/#/R-XTR-9755015 SLC29A1 transports RBV from extracellular region to cytosol IEA Xenopus tropicalis 6842 R-XTR-9755035 https://reactome.org/PathwayBrowser/#/R-XTR-9755035 SLC29A1 transports RBV from cytosol to extracellular region IEA Xenopus tropicalis 6842 R-XTR-9755044 https://reactome.org/PathwayBrowser/#/R-XTR-9755044 PNP trimer transforms RBV to T-CONH2 IEA Xenopus tropicalis 6842 R-XTR-9755078 https://reactome.org/PathwayBrowser/#/R-XTR-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Xenopus tropicalis 6843 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6843 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6843 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6843 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6843 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6843 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6843 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6843 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6843 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6843 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6843 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6843 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6843 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6843 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6843 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6843 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6843 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6843 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6843 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6843 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6844 R-BTA-9708759 https://reactome.org/PathwayBrowser/#/R-BTA-9708759 DHODH:FMN binds DHODH inhibitors IEA Bos taurus 6844 R-CEL-9708759 https://reactome.org/PathwayBrowser/#/R-CEL-9708759 DHODH:FMN binds DHODH inhibitors IEA Caenorhabditis elegans 6844 R-CFA-9708759 https://reactome.org/PathwayBrowser/#/R-CFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Canis familiaris 6844 R-DME-9708759 https://reactome.org/PathwayBrowser/#/R-DME-9708759 DHODH:FMN binds DHODH inhibitors IEA Drosophila melanogaster 6844 R-DRE-9708759 https://reactome.org/PathwayBrowser/#/R-DRE-9708759 DHODH:FMN binds DHODH inhibitors IEA Danio rerio 6844 R-GGA-9708759 https://reactome.org/PathwayBrowser/#/R-GGA-9708759 DHODH:FMN binds DHODH inhibitors IEA Gallus gallus 6844 R-HSA-9708759 https://reactome.org/PathwayBrowser/#/R-HSA-9708759 DHODH:FMN binds DHODH inhibitors TAS Homo sapiens 6844 R-MMU-9708759 https://reactome.org/PathwayBrowser/#/R-MMU-9708759 DHODH:FMN binds DHODH inhibitors IEA Mus musculus 6844 R-PFA-9708759 https://reactome.org/PathwayBrowser/#/R-PFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Plasmodium falciparum 6844 R-RNO-9708759 https://reactome.org/PathwayBrowser/#/R-RNO-9708759 DHODH:FMN binds DHODH inhibitors IEA Rattus norvegicus 6844 R-SPO-9708759 https://reactome.org/PathwayBrowser/#/R-SPO-9708759 DHODH:FMN binds DHODH inhibitors IEA Schizosaccharomyces pombe 6844 R-SSC-9708759 https://reactome.org/PathwayBrowser/#/R-SSC-9708759 DHODH:FMN binds DHODH inhibitors IEA Sus scrofa 6844 R-XTR-9708759 https://reactome.org/PathwayBrowser/#/R-XTR-9708759 DHODH:FMN binds DHODH inhibitors IEA Xenopus tropicalis 6845 R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 6845 R-BTA-9678749 https://reactome.org/PathwayBrowser/#/R-BTA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Bos taurus 6845 R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 6845 R-CEL-9678749 https://reactome.org/PathwayBrowser/#/R-CEL-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Caenorhabditis elegans 6845 R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 6845 R-CFA-9678749 https://reactome.org/PathwayBrowser/#/R-CFA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Canis familiaris 6845 R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 6845 R-DDI-9678749 https://reactome.org/PathwayBrowser/#/R-DDI-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Dictyostelium discoideum 6845 R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 6845 R-DME-9678749 https://reactome.org/PathwayBrowser/#/R-DME-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Drosophila melanogaster 6845 R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 6845 R-DRE-9678749 https://reactome.org/PathwayBrowser/#/R-DRE-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Danio rerio 6845 R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 6845 R-GGA-9678749 https://reactome.org/PathwayBrowser/#/R-GGA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Gallus gallus 6845 R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 6845 R-HSA-9678749 https://reactome.org/PathwayBrowser/#/R-HSA-9678749 IMPDH tetramers binds IMPDH inhibitors TAS Homo sapiens 6845 R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 6845 R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 6845 R-MMU-9678749 https://reactome.org/PathwayBrowser/#/R-MMU-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Mus musculus 6845 R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 6845 R-PFA-9678749 https://reactome.org/PathwayBrowser/#/R-PFA-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Plasmodium falciparum 6845 R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 6845 R-RNO-9678749 https://reactome.org/PathwayBrowser/#/R-RNO-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Rattus norvegicus 6845 R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 6845 R-SCE-9678749 https://reactome.org/PathwayBrowser/#/R-SCE-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Saccharomyces cerevisiae 6845 R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 6845 R-SPO-9678749 https://reactome.org/PathwayBrowser/#/R-SPO-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Schizosaccharomyces pombe 6845 R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 6845 R-SSC-9678749 https://reactome.org/PathwayBrowser/#/R-SSC-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Sus scrofa 6845 R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 6845 R-XTR-9678749 https://reactome.org/PathwayBrowser/#/R-XTR-9678749 IMPDH tetramers binds IMPDH inhibitors IEA Xenopus tropicalis 6846 R-BTA-140791 https://reactome.org/PathwayBrowser/#/R-BTA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Bos taurus 6846 R-BTA-140806 https://reactome.org/PathwayBrowser/#/R-BTA-140806 SERPINC1 binds SERPINC1 activators IEA Bos taurus 6846 R-BTA-140870 https://reactome.org/PathwayBrowser/#/R-BTA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Bos taurus 6846 R-BTA-140872 https://reactome.org/PathwayBrowser/#/R-BTA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Bos taurus 6846 R-CEL-140806 https://reactome.org/PathwayBrowser/#/R-CEL-140806 SERPINC1 binds SERPINC1 activators IEA Caenorhabditis elegans 6846 R-CFA-140791 https://reactome.org/PathwayBrowser/#/R-CFA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Canis familiaris 6846 R-CFA-140806 https://reactome.org/PathwayBrowser/#/R-CFA-140806 SERPINC1 binds SERPINC1 activators IEA Canis familiaris 6846 R-CFA-140870 https://reactome.org/PathwayBrowser/#/R-CFA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Canis familiaris 6846 R-CFA-140872 https://reactome.org/PathwayBrowser/#/R-CFA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Canis familiaris 6846 R-DME-140806 https://reactome.org/PathwayBrowser/#/R-DME-140806 SERPINC1 binds SERPINC1 activators IEA Drosophila melanogaster 6846 R-DRE-140806 https://reactome.org/PathwayBrowser/#/R-DRE-140806 SERPINC1 binds SERPINC1 activators IEA Danio rerio 6846 R-GGA-140791 https://reactome.org/PathwayBrowser/#/R-GGA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Gallus gallus 6846 R-GGA-140806 https://reactome.org/PathwayBrowser/#/R-GGA-140806 SERPINC1 binds SERPINC1 activators IEA Gallus gallus 6846 R-GGA-140870 https://reactome.org/PathwayBrowser/#/R-GGA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Gallus gallus 6846 R-GGA-140872 https://reactome.org/PathwayBrowser/#/R-GGA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Gallus gallus 6846 R-HSA-140791 https://reactome.org/PathwayBrowser/#/R-HSA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin TAS Homo sapiens 6846 R-HSA-140806 https://reactome.org/PathwayBrowser/#/R-HSA-140806 SERPINC1 binds SERPINC1 activators TAS Homo sapiens 6846 R-HSA-140870 https://reactome.org/PathwayBrowser/#/R-HSA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin TAS Homo sapiens 6846 R-HSA-140872 https://reactome.org/PathwayBrowser/#/R-HSA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators TAS Homo sapiens 6846 R-MMU-140791 https://reactome.org/PathwayBrowser/#/R-MMU-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Mus musculus 6846 R-MMU-140806 https://reactome.org/PathwayBrowser/#/R-MMU-140806 SERPINC1 binds SERPINC1 activators IEA Mus musculus 6846 R-MMU-140870 https://reactome.org/PathwayBrowser/#/R-MMU-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Mus musculus 6846 R-MMU-140872 https://reactome.org/PathwayBrowser/#/R-MMU-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Mus musculus 6846 R-RNO-140791 https://reactome.org/PathwayBrowser/#/R-RNO-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Rattus norvegicus 6846 R-RNO-140806 https://reactome.org/PathwayBrowser/#/R-RNO-140806 SERPINC1 binds SERPINC1 activators IEA Rattus norvegicus 6846 R-RNO-140870 https://reactome.org/PathwayBrowser/#/R-RNO-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Rattus norvegicus 6846 R-RNO-140872 https://reactome.org/PathwayBrowser/#/R-RNO-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Rattus norvegicus 6846 R-SSC-140791 https://reactome.org/PathwayBrowser/#/R-SSC-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Sus scrofa 6846 R-SSC-140806 https://reactome.org/PathwayBrowser/#/R-SSC-140806 SERPINC1 binds SERPINC1 activators IEA Sus scrofa 6846 R-SSC-140870 https://reactome.org/PathwayBrowser/#/R-SSC-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Sus scrofa 6846 R-SSC-140872 https://reactome.org/PathwayBrowser/#/R-SSC-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Sus scrofa 6846 R-XTR-140791 https://reactome.org/PathwayBrowser/#/R-XTR-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin IEA Xenopus tropicalis 6846 R-XTR-140806 https://reactome.org/PathwayBrowser/#/R-XTR-140806 SERPINC1 binds SERPINC1 activators IEA Xenopus tropicalis 6846 R-XTR-140870 https://reactome.org/PathwayBrowser/#/R-XTR-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin IEA Xenopus tropicalis 6846 R-XTR-140872 https://reactome.org/PathwayBrowser/#/R-XTR-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators IEA Xenopus tropicalis 6847 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 6847 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 6847 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 6847 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 6847 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 6847 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 6847 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 6847 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 6847 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 6848 R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 6848 R-BTA-9652580 https://reactome.org/PathwayBrowser/#/R-BTA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Bos taurus 6848 R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 6848 R-CFA-9652580 https://reactome.org/PathwayBrowser/#/R-CFA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Canis familiaris 6848 R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 6848 R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 6848 R-DME-9652580 https://reactome.org/PathwayBrowser/#/R-DME-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Drosophila melanogaster 6848 R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 6848 R-GGA-9652580 https://reactome.org/PathwayBrowser/#/R-GGA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Gallus gallus 6848 R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 6848 R-HSA-9652580 https://reactome.org/PathwayBrowser/#/R-HSA-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) TAS Homo sapiens 6848 R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 6848 R-MMU-9652580 https://reactome.org/PathwayBrowser/#/R-MMU-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Mus musculus 6848 R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 6848 R-RNO-9652580 https://reactome.org/PathwayBrowser/#/R-RNO-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Rattus norvegicus 6848 R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 6848 R-SSC-9652580 https://reactome.org/PathwayBrowser/#/R-SSC-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Sus scrofa 6848 R-XTR-9652580 https://reactome.org/PathwayBrowser/#/R-XTR-9652580 SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) IEA Xenopus tropicalis 6849 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 6849 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 6849 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 6849 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 6849 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 6849 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 6849 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 6849 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 6849 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 6849 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 6849 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 6849 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 6851 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 6851 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 6851 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 6851 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 6851 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 6851 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 6851 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 6851 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 6851 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 6851 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 6851 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 6851 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 6851 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 6851 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 6851 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 6851 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 6851 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 6851 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 6851 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 6851 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 6852 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus 6852 R-BTA-9679787 https://reactome.org/PathwayBrowser/#/R-BTA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Bos taurus 6852 R-CFA-3769447 https://reactome.org/PathwayBrowser/#/R-CFA-3769447 HDAC1:2-containing complex deacetylate histones IEA Canis familiaris 6852 R-CFA-9679787 https://reactome.org/PathwayBrowser/#/R-CFA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Canis familiaris 6852 R-DDI-3769447 https://reactome.org/PathwayBrowser/#/R-DDI-3769447 HDAC1:2-containing complex deacetylate histones IEA Dictyostelium discoideum 6852 R-DDI-9679787 https://reactome.org/PathwayBrowser/#/R-DDI-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Dictyostelium discoideum 6852 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster 6852 R-DME-9679787 https://reactome.org/PathwayBrowser/#/R-DME-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Drosophila melanogaster 6852 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus 6852 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus 6852 R-HSA-3769447 https://reactome.org/PathwayBrowser/#/R-HSA-3769447 HDAC1:2-containing complex deacetylate histones TAS Homo sapiens 6852 R-HSA-9679787 https://reactome.org/PathwayBrowser/#/R-HSA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors TAS Homo sapiens 6852 R-MMU-3769447 https://reactome.org/PathwayBrowser/#/R-MMU-3769447 HDAC1:2-containing complex deacetylate histones IEA Mus musculus 6852 R-MMU-9679787 https://reactome.org/PathwayBrowser/#/R-MMU-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Mus musculus 6852 R-RNO-9679787 https://reactome.org/PathwayBrowser/#/R-RNO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Rattus norvegicus 6852 R-SCE-3769447 https://reactome.org/PathwayBrowser/#/R-SCE-3769447 HDAC1:2-containing complex deacetylate histones IEA Saccharomyces cerevisiae 6852 R-SCE-9679787 https://reactome.org/PathwayBrowser/#/R-SCE-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Saccharomyces cerevisiae 6852 R-SPO-3769447 https://reactome.org/PathwayBrowser/#/R-SPO-3769447 HDAC1:2-containing complex deacetylate histones IEA Schizosaccharomyces pombe 6852 R-SPO-9679787 https://reactome.org/PathwayBrowser/#/R-SPO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Schizosaccharomyces pombe 6852 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa 6852 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa 6852 R-XTR-9679787 https://reactome.org/PathwayBrowser/#/R-XTR-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Xenopus tropicalis 6853 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 6853 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 6853 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 6853 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 6853 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 6853 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 6853 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 6853 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 6853 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 6853 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 6853 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 6853 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 6853 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 6853 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 6853 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 6853 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 6881 R-BTA-1067667 https://reactome.org/PathwayBrowser/#/R-BTA-1067667 IL6 binds IL6R IEA Bos taurus 6881 R-BTA-9681294 https://reactome.org/PathwayBrowser/#/R-BTA-9681294 IL6R binds IL6R inhibitors IEA Bos taurus 6881 R-CEL-9681294 https://reactome.org/PathwayBrowser/#/R-CEL-9681294 IL6R binds IL6R inhibitors IEA Caenorhabditis elegans 6881 R-CFA-1067667 https://reactome.org/PathwayBrowser/#/R-CFA-1067667 IL6 binds IL6R IEA Canis familiaris 6881 R-CFA-9681294 https://reactome.org/PathwayBrowser/#/R-CFA-9681294 IL6R binds IL6R inhibitors IEA Canis familiaris 6881 R-DRE-1067667 https://reactome.org/PathwayBrowser/#/R-DRE-1067667 IL6 binds IL6R IEA Danio rerio 6881 R-DRE-9681294 https://reactome.org/PathwayBrowser/#/R-DRE-9681294 IL6R binds IL6R inhibitors IEA Danio rerio 6881 R-GGA-1067667 https://reactome.org/PathwayBrowser/#/R-GGA-1067667 IL6 binds IL6R IEA Gallus gallus 6881 R-GGA-9681294 https://reactome.org/PathwayBrowser/#/R-GGA-9681294 IL6R binds IL6R inhibitors IEA Gallus gallus 6881 R-HSA-1067667 https://reactome.org/PathwayBrowser/#/R-HSA-1067667 IL6 binds IL6R TAS Homo sapiens 6881 R-HSA-9681294 https://reactome.org/PathwayBrowser/#/R-HSA-9681294 IL6R binds IL6R inhibitors TAS Homo sapiens 6881 R-MMU-1067667 https://reactome.org/PathwayBrowser/#/R-MMU-1067667 IL6 binds IL6R IEA Mus musculus 6881 R-MMU-9681294 https://reactome.org/PathwayBrowser/#/R-MMU-9681294 IL6R binds IL6R inhibitors IEA Mus musculus 6881 R-RNO-1067667 https://reactome.org/PathwayBrowser/#/R-RNO-1067667 IL6 binds IL6R IEA Rattus norvegicus 6881 R-RNO-9681294 https://reactome.org/PathwayBrowser/#/R-RNO-9681294 IL6R binds IL6R inhibitors IEA Rattus norvegicus 6882 R-HSA-1248677 https://reactome.org/PathwayBrowser/#/R-HSA-1248677 Inactivation of over-expressed wild type EGFR by Cetuximab recombinant antibody TAS Homo sapiens 6884 R-BTA-9691621 https://reactome.org/PathwayBrowser/#/R-BTA-9691621 C5 binds C5 inhibitors IEA Bos taurus 6884 R-CFA-9691621 https://reactome.org/PathwayBrowser/#/R-CFA-9691621 C5 binds C5 inhibitors IEA Canis familiaris 6884 R-GGA-9691621 https://reactome.org/PathwayBrowser/#/R-GGA-9691621 C5 binds C5 inhibitors IEA Gallus gallus 6884 R-HSA-9691621 https://reactome.org/PathwayBrowser/#/R-HSA-9691621 C5 binds C5 inhibitors TAS Homo sapiens 6884 R-MMU-9691621 https://reactome.org/PathwayBrowser/#/R-MMU-9691621 C5 binds C5 inhibitors IEA Mus musculus 6884 R-RNO-9691621 https://reactome.org/PathwayBrowser/#/R-RNO-9691621 C5 binds C5 inhibitors IEA Rattus norvegicus 6884 R-SSC-9691621 https://reactome.org/PathwayBrowser/#/R-SSC-9691621 C5 binds C5 inhibitors IEA Sus scrofa 6890 R-BTA-9724685 https://reactome.org/PathwayBrowser/#/R-BTA-9724685 IgE binds omalizumab IEA Bos taurus 6890 R-CFA-9724685 https://reactome.org/PathwayBrowser/#/R-CFA-9724685 IgE binds omalizumab IEA Canis familiaris 6890 R-GGA-9724685 https://reactome.org/PathwayBrowser/#/R-GGA-9724685 IgE binds omalizumab IEA Gallus gallus 6890 R-HSA-9724685 https://reactome.org/PathwayBrowser/#/R-HSA-9724685 IgE binds omalizumab TAS Homo sapiens 6890 R-MMU-9724685 https://reactome.org/PathwayBrowser/#/R-MMU-9724685 IgE binds omalizumab IEA Mus musculus 6890 R-RNO-9724685 https://reactome.org/PathwayBrowser/#/R-RNO-9724685 IgE binds omalizumab IEA Rattus norvegicus 6890 R-SSC-9724685 https://reactome.org/PathwayBrowser/#/R-SSC-9724685 IgE binds omalizumab IEA Sus scrofa 6896 R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(25-32) binds to AGTR1 IEA Bos taurus 6896 R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGTR1 IEA Bos taurus 6896 R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(25-32) binds to AGTR1 IEA Caenorhabditis elegans 6896 R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGTR1 IEA Caenorhabditis elegans 6896 R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(25-32) binds to AGTR1 IEA Canis familiaris 6896 R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGTR1 IEA Canis familiaris 6896 R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(25-32) binds to AGTR1 IEA Drosophila melanogaster 6896 R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGTR1 IEA Drosophila melanogaster 6896 R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(25-32) binds to AGTR1 IEA Danio rerio 6896 R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGTR1 IEA Danio rerio 6896 R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(25-32) binds to AGTR1 IEA Gallus gallus 6896 R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGTR1 IEA Gallus gallus 6896 R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(25-32) binds to AGTR1 TAS Homo sapiens 6896 R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGTR1 TAS Homo sapiens 6896 R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(25-32) binds to AGTR1 IEA Mus musculus 6896 R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGTR1 IEA Mus musculus 6896 R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(25-32) binds to AGTR1 IEA Rattus norvegicus 6896 R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGTR1 IEA Rattus norvegicus 6896 R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(25-32) binds to AGTR1 IEA Sus scrofa 6896 R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGTR1 IEA Sus scrofa 6912 R-BTA-451895 https://reactome.org/PathwayBrowser/#/R-BTA-451895 IL2RG binds JAK3 IEA Bos taurus 6912 R-BTA-9679028 https://reactome.org/PathwayBrowser/#/R-BTA-9679028 JAK3 binds JAK3 inhibitors IEA Bos taurus 6912 R-BTA-9691421 https://reactome.org/PathwayBrowser/#/R-BTA-9691421 BTK binds BTK inhibitors IEA Bos taurus 6912 R-CFA-9679028 https://reactome.org/PathwayBrowser/#/R-CFA-9679028 JAK3 binds JAK3 inhibitors IEA Canis familiaris 6912 R-CFA-9691421 https://reactome.org/PathwayBrowser/#/R-CFA-9691421 BTK binds BTK inhibitors IEA Canis familiaris 6912 R-DME-9679028 https://reactome.org/PathwayBrowser/#/R-DME-9679028 JAK3 binds JAK3 inhibitors IEA Drosophila melanogaster 6912 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus 6912 R-HSA-451895 https://reactome.org/PathwayBrowser/#/R-HSA-451895 IL2RG binds JAK3 TAS Homo sapiens 6912 R-HSA-9679028 https://reactome.org/PathwayBrowser/#/R-HSA-9679028 JAK3 binds JAK3 inhibitors TAS Homo sapiens 6912 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens 6912 R-MMU-451895 https://reactome.org/PathwayBrowser/#/R-MMU-451895 IL2RG binds JAK3 IEA Mus musculus 6912 R-MMU-9679028 https://reactome.org/PathwayBrowser/#/R-MMU-9679028 JAK3 binds JAK3 inhibitors IEA Mus musculus 6912 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus 6912 R-RNO-9679028 https://reactome.org/PathwayBrowser/#/R-RNO-9679028 JAK3 binds JAK3 inhibitors IEA Rattus norvegicus 6912 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus 6912 R-SSC-451895 https://reactome.org/PathwayBrowser/#/R-SSC-451895 IL2RG binds JAK3 IEA Sus scrofa 6912 R-SSC-9679028 https://reactome.org/PathwayBrowser/#/R-SSC-9679028 JAK3 binds JAK3 inhibitors IEA Sus scrofa 6912 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa 6912 R-XTR-9679028 https://reactome.org/PathwayBrowser/#/R-XTR-9679028 JAK3 binds JAK3 inhibitors IEA Xenopus tropicalis 6921 R-BTA-209760 https://reactome.org/PathwayBrowser/#/R-BTA-209760 Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen IEA Bos taurus 6921 R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 6921 R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 6921 R-BTA-209944 https://reactome.org/PathwayBrowser/#/R-BTA-209944 25(OH)D binds GC IEA Bos taurus 6921 R-BTA-350158 https://reactome.org/PathwayBrowser/#/R-BTA-350158 LGMN hydrolyzes GC, releasing CUBN and 25(OH)D IEA Bos taurus 6921 R-BTA-350168 https://reactome.org/PathwayBrowser/#/R-BTA-350168 LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D IEA Bos taurus 6921 R-BTA-350186 https://reactome.org/PathwayBrowser/#/R-BTA-350186 CUBN binds GC:25(OH)D IEA Bos taurus 6921 R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 6921 R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 6921 R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 6921 R-CFA-209944 https://reactome.org/PathwayBrowser/#/R-CFA-209944 25(OH)D binds GC IEA Canis familiaris 6921 R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 6921 R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 6921 R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 6921 R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 6921 R-GGA-209944 https://reactome.org/PathwayBrowser/#/R-GGA-209944 25(OH)D binds GC IEA Gallus gallus 6921 R-HSA-209760 https://reactome.org/PathwayBrowser/#/R-HSA-209760 Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen TAS Homo sapiens 6921 R-HSA-209766 https://reactome.org/PathwayBrowser/#/R-HSA-209766 25(OH)D translocates from lysosomal lumen to cytosol TAS Homo sapiens 6921 R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 6921 R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 6921 R-HSA-209944 https://reactome.org/PathwayBrowser/#/R-HSA-209944 25(OH)D binds GC TAS Homo sapiens 6921 R-HSA-350158 https://reactome.org/PathwayBrowser/#/R-HSA-350158 LGMN hydrolyzes GC, releasing CUBN and 25(OH)D TAS Homo sapiens 6921 R-HSA-350168 https://reactome.org/PathwayBrowser/#/R-HSA-350168 LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D TAS Homo sapiens 6921 R-HSA-350186 https://reactome.org/PathwayBrowser/#/R-HSA-350186 CUBN binds GC:25(OH)D TAS Homo sapiens 6921 R-HSA-5602186 https://reactome.org/PathwayBrowser/#/R-HSA-5602186 Defective CYP27B1 does not hydroxylate CDL TAS Homo sapiens 6921 R-HSA-6807242 https://reactome.org/PathwayBrowser/#/R-HSA-6807242 25(OH)D translocates from ER membrane to extracellular region TAS Homo sapiens 6921 R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 6921 R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 6921 R-MMU-209944 https://reactome.org/PathwayBrowser/#/R-MMU-209944 25(OH)D binds GC IEA Mus musculus 6921 R-RNO-209760 https://reactome.org/PathwayBrowser/#/R-RNO-209760 Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen IEA Rattus norvegicus 6921 R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 6921 R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 6921 R-RNO-209944 https://reactome.org/PathwayBrowser/#/R-RNO-209944 25(OH)D binds GC IEA Rattus norvegicus 6921 R-RNO-350158 https://reactome.org/PathwayBrowser/#/R-RNO-350158 LGMN hydrolyzes GC, releasing CUBN and 25(OH)D IEA Rattus norvegicus 6921 R-RNO-350168 https://reactome.org/PathwayBrowser/#/R-RNO-350168 LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D IEA Rattus norvegicus 6921 R-RNO-350186 https://reactome.org/PathwayBrowser/#/R-RNO-350186 CUBN binds GC:25(OH)D IEA Rattus norvegicus 6921 R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 6921 R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 6921 R-SSC-209944 https://reactome.org/PathwayBrowser/#/R-SSC-209944 25(OH)D binds GC IEA Sus scrofa 6921 R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 6921 R-XTR-209944 https://reactome.org/PathwayBrowser/#/R-XTR-209944 25(OH)D binds GC IEA Xenopus tropicalis 6922 R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 6922 R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 6922 R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 6922 R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 6922 R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 6922 R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 6922 R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 6922 R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 6942 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 6942 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 6942 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 6942 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 6942 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 6942 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 6942 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 6942 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 6942 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 6942 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 6942 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 6943 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 6943 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 6943 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 6943 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 6943 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 6943 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 6943 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 6943 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 6943 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 6943 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 6943 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 6945 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 6945 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 6945 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 6945 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 6945 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 6945 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 6945 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 6945 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 6945 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 6945 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 6945 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 6947 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 6947 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 6947 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 6947 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 6947 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 6947 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 6947 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 6947 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 6947 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 6947 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 6947 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 6949 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 6949 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 6949 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 6949 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 6949 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 6949 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 6949 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 6949 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 6949 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 6949 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 6949 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 6953 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 6953 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 6953 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 6953 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 6953 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 6953 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 6953 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 6953 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 6953 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 6953 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 6953 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 6953 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 6953 R-HSA-9679816 https://reactome.org/PathwayBrowser/#/R-HSA-9679816 SIGMAR1 binds dextromethorphan TAS Homo sapiens 6953 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 6953 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 6953 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 6953 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 6953 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 6953 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 6953 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 6953 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 6953 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 6953 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 6962 R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 6962 R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 6962 R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 6962 R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 6962 R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 6962 R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 6962 R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 6962 R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 6962 R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 6962 R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 6962 R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 6972 R-BTA-445753 https://reactome.org/PathwayBrowser/#/R-BTA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Bos taurus 6972 R-BTA-9681763 https://reactome.org/PathwayBrowser/#/R-BTA-9681763 IL1R1 binds IL1R1 inhibitors IEA Bos taurus 6972 R-CFA-445753 https://reactome.org/PathwayBrowser/#/R-CFA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Canis familiaris 6972 R-CFA-9681763 https://reactome.org/PathwayBrowser/#/R-CFA-9681763 IL1R1 binds IL1R1 inhibitors IEA Canis familiaris 6972 R-GGA-445753 https://reactome.org/PathwayBrowser/#/R-GGA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Gallus gallus 6972 R-GGA-9681763 https://reactome.org/PathwayBrowser/#/R-GGA-9681763 IL1R1 binds IL1R1 inhibitors IEA Gallus gallus 6972 R-HSA-445753 https://reactome.org/PathwayBrowser/#/R-HSA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 TAS Homo sapiens 6972 R-HSA-9681763 https://reactome.org/PathwayBrowser/#/R-HSA-9681763 IL1R1 binds IL1R1 inhibitors TAS Homo sapiens 6972 R-MMU-445753 https://reactome.org/PathwayBrowser/#/R-MMU-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Mus musculus 6972 R-MMU-9681763 https://reactome.org/PathwayBrowser/#/R-MMU-9681763 IL1R1 binds IL1R1 inhibitors IEA Mus musculus 6972 R-RNO-445753 https://reactome.org/PathwayBrowser/#/R-RNO-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Rattus norvegicus 6972 R-RNO-9681763 https://reactome.org/PathwayBrowser/#/R-RNO-9681763 IL1R1 binds IL1R1 inhibitors IEA Rattus norvegicus 6972 R-SSC-445753 https://reactome.org/PathwayBrowser/#/R-SSC-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Sus scrofa 6972 R-SSC-9681763 https://reactome.org/PathwayBrowser/#/R-SSC-9681763 IL1R1 binds IL1R1 inhibitors IEA Sus scrofa 6972 R-XTR-445753 https://reactome.org/PathwayBrowser/#/R-XTR-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Xenopus tropicalis 6972 R-XTR-9681763 https://reactome.org/PathwayBrowser/#/R-XTR-9681763 IL1R1 binds IL1R1 inhibitors IEA Xenopus tropicalis 6976 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 6976 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 6976 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 6976 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 6976 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 6976 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 6976 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 6976 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 6976 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 6976 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 6976 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 6976 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 6976 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 6976 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 6976 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 6976 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 6976 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 6976 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 6981 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 6981 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 6981 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 6981 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 6981 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 6981 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 6981 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 6981 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 6981 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 6981 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 7006 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus 7006 R-BTA-9679787 https://reactome.org/PathwayBrowser/#/R-BTA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Bos taurus 7006 R-CFA-3769447 https://reactome.org/PathwayBrowser/#/R-CFA-3769447 HDAC1:2-containing complex deacetylate histones IEA Canis familiaris 7006 R-CFA-9679787 https://reactome.org/PathwayBrowser/#/R-CFA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Canis familiaris 7006 R-DDI-3769447 https://reactome.org/PathwayBrowser/#/R-DDI-3769447 HDAC1:2-containing complex deacetylate histones IEA Dictyostelium discoideum 7006 R-DDI-9679787 https://reactome.org/PathwayBrowser/#/R-DDI-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Dictyostelium discoideum 7006 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster 7006 R-DME-9679787 https://reactome.org/PathwayBrowser/#/R-DME-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Drosophila melanogaster 7006 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus 7006 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus 7006 R-HSA-3769447 https://reactome.org/PathwayBrowser/#/R-HSA-3769447 HDAC1:2-containing complex deacetylate histones TAS Homo sapiens 7006 R-HSA-9679787 https://reactome.org/PathwayBrowser/#/R-HSA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors TAS Homo sapiens 7006 R-MMU-3769447 https://reactome.org/PathwayBrowser/#/R-MMU-3769447 HDAC1:2-containing complex deacetylate histones IEA Mus musculus 7006 R-MMU-9679787 https://reactome.org/PathwayBrowser/#/R-MMU-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Mus musculus 7006 R-RNO-9679787 https://reactome.org/PathwayBrowser/#/R-RNO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Rattus norvegicus 7006 R-SCE-3769447 https://reactome.org/PathwayBrowser/#/R-SCE-3769447 HDAC1:2-containing complex deacetylate histones IEA Saccharomyces cerevisiae 7006 R-SCE-9679787 https://reactome.org/PathwayBrowser/#/R-SCE-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Saccharomyces cerevisiae 7006 R-SPO-3769447 https://reactome.org/PathwayBrowser/#/R-SPO-3769447 HDAC1:2-containing complex deacetylate histones IEA Schizosaccharomyces pombe 7006 R-SPO-9679787 https://reactome.org/PathwayBrowser/#/R-SPO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Schizosaccharomyces pombe 7006 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa 7006 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa 7006 R-XTR-9679787 https://reactome.org/PathwayBrowser/#/R-XTR-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Xenopus tropicalis 7009 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus 7009 R-BTA-9679787 https://reactome.org/PathwayBrowser/#/R-BTA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Bos taurus 7009 R-CFA-3769447 https://reactome.org/PathwayBrowser/#/R-CFA-3769447 HDAC1:2-containing complex deacetylate histones IEA Canis familiaris 7009 R-CFA-9679787 https://reactome.org/PathwayBrowser/#/R-CFA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Canis familiaris 7009 R-DDI-3769447 https://reactome.org/PathwayBrowser/#/R-DDI-3769447 HDAC1:2-containing complex deacetylate histones IEA Dictyostelium discoideum 7009 R-DDI-9679787 https://reactome.org/PathwayBrowser/#/R-DDI-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Dictyostelium discoideum 7009 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster 7009 R-DME-9679787 https://reactome.org/PathwayBrowser/#/R-DME-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Drosophila melanogaster 7009 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus 7009 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus 7009 R-HSA-3769447 https://reactome.org/PathwayBrowser/#/R-HSA-3769447 HDAC1:2-containing complex deacetylate histones TAS Homo sapiens 7009 R-HSA-9679787 https://reactome.org/PathwayBrowser/#/R-HSA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors TAS Homo sapiens 7009 R-MMU-3769447 https://reactome.org/PathwayBrowser/#/R-MMU-3769447 HDAC1:2-containing complex deacetylate histones IEA Mus musculus 7009 R-MMU-9679787 https://reactome.org/PathwayBrowser/#/R-MMU-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Mus musculus 7009 R-RNO-9679787 https://reactome.org/PathwayBrowser/#/R-RNO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Rattus norvegicus 7009 R-SCE-3769447 https://reactome.org/PathwayBrowser/#/R-SCE-3769447 HDAC1:2-containing complex deacetylate histones IEA Saccharomyces cerevisiae 7009 R-SCE-9679787 https://reactome.org/PathwayBrowser/#/R-SCE-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Saccharomyces cerevisiae 7009 R-SPO-3769447 https://reactome.org/PathwayBrowser/#/R-SPO-3769447 HDAC1:2-containing complex deacetylate histones IEA Schizosaccharomyces pombe 7009 R-SPO-9679787 https://reactome.org/PathwayBrowser/#/R-SPO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Schizosaccharomyces pombe 7009 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa 7009 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa 7009 R-XTR-9679787 https://reactome.org/PathwayBrowser/#/R-XTR-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Xenopus tropicalis 702 R-BTA-9702849 https://reactome.org/PathwayBrowser/#/R-BTA-9702849 CALCR binds gepants IEA Bos taurus 702 R-CEL-9702849 https://reactome.org/PathwayBrowser/#/R-CEL-9702849 CALCR binds gepants IEA Caenorhabditis elegans 702 R-CFA-9702849 https://reactome.org/PathwayBrowser/#/R-CFA-9702849 CALCR binds gepants IEA Canis familiaris 702 R-DME-9702849 https://reactome.org/PathwayBrowser/#/R-DME-9702849 CALCR binds gepants IEA Drosophila melanogaster 702 R-GGA-9702849 https://reactome.org/PathwayBrowser/#/R-GGA-9702849 CALCR binds gepants IEA Gallus gallus 702 R-HSA-9702849 https://reactome.org/PathwayBrowser/#/R-HSA-9702849 CALCR binds gepants TAS Homo sapiens 702 R-MMU-9702849 https://reactome.org/PathwayBrowser/#/R-MMU-9702849 CALCR binds gepants IEA Mus musculus 702 R-RNO-9702849 https://reactome.org/PathwayBrowser/#/R-RNO-9702849 CALCR binds gepants IEA Rattus norvegicus 702 R-SSC-9702849 https://reactome.org/PathwayBrowser/#/R-SSC-9702849 CALCR binds gepants IEA Sus scrofa 702 R-XTR-9702849 https://reactome.org/PathwayBrowser/#/R-XTR-9702849 CALCR binds gepants IEA Xenopus tropicalis 703 R-BTA-9702849 https://reactome.org/PathwayBrowser/#/R-BTA-9702849 CALCR binds gepants IEA Bos taurus 703 R-CEL-9702849 https://reactome.org/PathwayBrowser/#/R-CEL-9702849 CALCR binds gepants IEA Caenorhabditis elegans 703 R-CFA-9702849 https://reactome.org/PathwayBrowser/#/R-CFA-9702849 CALCR binds gepants IEA Canis familiaris 703 R-DME-9702849 https://reactome.org/PathwayBrowser/#/R-DME-9702849 CALCR binds gepants IEA Drosophila melanogaster 703 R-GGA-9702849 https://reactome.org/PathwayBrowser/#/R-GGA-9702849 CALCR binds gepants IEA Gallus gallus 703 R-HSA-9702849 https://reactome.org/PathwayBrowser/#/R-HSA-9702849 CALCR binds gepants TAS Homo sapiens 703 R-MMU-9702849 https://reactome.org/PathwayBrowser/#/R-MMU-9702849 CALCR binds gepants IEA Mus musculus 703 R-RNO-9702849 https://reactome.org/PathwayBrowser/#/R-RNO-9702849 CALCR binds gepants IEA Rattus norvegicus 703 R-SSC-9702849 https://reactome.org/PathwayBrowser/#/R-SSC-9702849 CALCR binds gepants IEA Sus scrofa 703 R-XTR-9702849 https://reactome.org/PathwayBrowser/#/R-XTR-9702849 CALCR binds gepants IEA Xenopus tropicalis 7045 R-BTA-9712274 https://reactome.org/PathwayBrowser/#/R-BTA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Bos taurus 7045 R-BTA-9716258 https://reactome.org/PathwayBrowser/#/R-BTA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Bos taurus 7045 R-BTA-9755505 https://reactome.org/PathwayBrowser/#/R-BTA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Bos taurus 7045 R-CEL-9712274 https://reactome.org/PathwayBrowser/#/R-CEL-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Caenorhabditis elegans 7045 R-CEL-9755505 https://reactome.org/PathwayBrowser/#/R-CEL-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Caenorhabditis elegans 7045 R-CFA-9712274 https://reactome.org/PathwayBrowser/#/R-CFA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Canis familiaris 7045 R-CFA-9716258 https://reactome.org/PathwayBrowser/#/R-CFA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Canis familiaris 7045 R-CFA-9755505 https://reactome.org/PathwayBrowser/#/R-CFA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Canis familiaris 7045 R-DDI-9712274 https://reactome.org/PathwayBrowser/#/R-DDI-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Dictyostelium discoideum 7045 R-DDI-9755505 https://reactome.org/PathwayBrowser/#/R-DDI-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Dictyostelium discoideum 7045 R-DME-9712274 https://reactome.org/PathwayBrowser/#/R-DME-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Drosophila melanogaster 7045 R-DME-9755505 https://reactome.org/PathwayBrowser/#/R-DME-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Drosophila melanogaster 7045 R-DRE-9712274 https://reactome.org/PathwayBrowser/#/R-DRE-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Danio rerio 7045 R-DRE-9755505 https://reactome.org/PathwayBrowser/#/R-DRE-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Danio rerio 7045 R-GGA-9712274 https://reactome.org/PathwayBrowser/#/R-GGA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Gallus gallus 7045 R-GGA-9716258 https://reactome.org/PathwayBrowser/#/R-GGA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Gallus gallus 7045 R-GGA-9755505 https://reactome.org/PathwayBrowser/#/R-GGA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Gallus gallus 7045 R-HSA-9712274 https://reactome.org/PathwayBrowser/#/R-HSA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 TAS Homo sapiens 7045 R-HSA-9716258 https://reactome.org/PathwayBrowser/#/R-HSA-9716258 Dimethyl fumarate modifies Cys191 in GSDMD TAS Homo sapiens 7045 R-HSA-9755505 https://reactome.org/PathwayBrowser/#/R-HSA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 TAS Homo sapiens 7045 R-MMU-9712274 https://reactome.org/PathwayBrowser/#/R-MMU-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Mus musculus 7045 R-MMU-9716258 https://reactome.org/PathwayBrowser/#/R-MMU-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Mus musculus 7045 R-MMU-9755505 https://reactome.org/PathwayBrowser/#/R-MMU-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Mus musculus 7045 R-RNO-9712274 https://reactome.org/PathwayBrowser/#/R-RNO-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Rattus norvegicus 7045 R-RNO-9716258 https://reactome.org/PathwayBrowser/#/R-RNO-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Rattus norvegicus 7045 R-RNO-9755505 https://reactome.org/PathwayBrowser/#/R-RNO-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Rattus norvegicus 7045 R-SSC-9712274 https://reactome.org/PathwayBrowser/#/R-SSC-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Sus scrofa 7045 R-SSC-9716258 https://reactome.org/PathwayBrowser/#/R-SSC-9716258 Dimethyl fumarate modifies Cys191 in GSDMD IEA Sus scrofa 7045 R-SSC-9755505 https://reactome.org/PathwayBrowser/#/R-SSC-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Sus scrofa 7045 R-XTR-9712274 https://reactome.org/PathwayBrowser/#/R-XTR-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 IEA Xenopus tropicalis 7045 R-XTR-9755505 https://reactome.org/PathwayBrowser/#/R-XTR-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 IEA Xenopus tropicalis 7047 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 7047 R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 7047 R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 7047 R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 7047 R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 7047 R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 7047 R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 7047 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 7047 R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 7047 R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 7047 R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 7047 R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 7047 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 7047 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 7047 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 7047 R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 7047 R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 7053 R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 7054 R-BTA-9707353 https://reactome.org/PathwayBrowser/#/R-BTA-9707353 CYP19A1 binds Aromatase inhibitors IEA Bos taurus 7054 R-CEL-9707353 https://reactome.org/PathwayBrowser/#/R-CEL-9707353 CYP19A1 binds Aromatase inhibitors IEA Caenorhabditis elegans 7054 R-CFA-9707353 https://reactome.org/PathwayBrowser/#/R-CFA-9707353 CYP19A1 binds Aromatase inhibitors IEA Canis familiaris 7054 R-DME-9707353 https://reactome.org/PathwayBrowser/#/R-DME-9707353 CYP19A1 binds Aromatase inhibitors IEA Drosophila melanogaster 7054 R-DRE-9707353 https://reactome.org/PathwayBrowser/#/R-DRE-9707353 CYP19A1 binds Aromatase inhibitors IEA Danio rerio 7054 R-GGA-9707353 https://reactome.org/PathwayBrowser/#/R-GGA-9707353 CYP19A1 binds Aromatase inhibitors IEA Gallus gallus 7054 R-HSA-9707353 https://reactome.org/PathwayBrowser/#/R-HSA-9707353 CYP19A1 binds Aromatase inhibitors TAS Homo sapiens 7054 R-MMU-9707353 https://reactome.org/PathwayBrowser/#/R-MMU-9707353 CYP19A1 binds Aromatase inhibitors IEA Mus musculus 7054 R-RNO-9707353 https://reactome.org/PathwayBrowser/#/R-RNO-9707353 CYP19A1 binds Aromatase inhibitors IEA Rattus norvegicus 7054 R-SSC-9707353 https://reactome.org/PathwayBrowser/#/R-SSC-9707353 CYP19A1 binds Aromatase inhibitors IEA Sus scrofa 7054 R-XTR-9707353 https://reactome.org/PathwayBrowser/#/R-XTR-9707353 CYP19A1 binds Aromatase inhibitors IEA Xenopus tropicalis 7059 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7059 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7059 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7059 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7059 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7059 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7059 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7059 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7059 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7059 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7059 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7059 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7059 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7059 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7059 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7059 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7059 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7059 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7059 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7059 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7059 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7059 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7061 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7061 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7061 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7061 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7061 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7061 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7061 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7061 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7061 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7061 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7061 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7061 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7061 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7061 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7061 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7061 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7061 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7061 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7061 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7061 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7061 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7061 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7062 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7062 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7062 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7062 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7062 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7062 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7062 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7062 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7062 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7062 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7062 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7062 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7062 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7062 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7062 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7062 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7062 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7062 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7062 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7062 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7062 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7062 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7063 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 7063 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 7063 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 7063 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 7063 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 7063 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 7063 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 7063 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 7063 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 7063 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 7063 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 7063 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 7063 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 7063 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 7063 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 7063 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 7063 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 7063 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 7063 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 7063 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 7067 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7067 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7067 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7067 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7067 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7067 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7067 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7067 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7067 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7067 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7067 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7067 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7067 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7067 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7067 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7067 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7067 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7067 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7067 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7067 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7067 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7067 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7068 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7068 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7068 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7068 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7068 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7068 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7068 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7068 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7068 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7068 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7068 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7068 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7068 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7068 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7068 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7068 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7068 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7068 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7068 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7068 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7068 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7068 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7069 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 7069 R-BTA-8937419 https://reactome.org/PathwayBrowser/#/R-BTA-8937419 CBR3 reduces DOX to DOXOL IEA Bos taurus 7069 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 7069 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 7069 R-CFA-8937419 https://reactome.org/PathwayBrowser/#/R-CFA-8937419 CBR3 reduces DOX to DOXOL IEA Canis familiaris 7069 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 7069 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 7069 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 7069 R-DRE-8937419 https://reactome.org/PathwayBrowser/#/R-DRE-8937419 CBR3 reduces DOX to DOXOL IEA Danio rerio 7069 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 7069 R-GGA-8937419 https://reactome.org/PathwayBrowser/#/R-GGA-8937419 CBR3 reduces DOX to DOXOL IEA Gallus gallus 7069 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 7069 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 7069 R-HSA-8937419 https://reactome.org/PathwayBrowser/#/R-HSA-8937419 CBR3 reduces DOX to DOXOL TAS Homo sapiens 7069 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 7069 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 7069 R-MMU-8937419 https://reactome.org/PathwayBrowser/#/R-MMU-8937419 CBR3 reduces DOX to DOXOL IEA Mus musculus 7069 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 7069 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 7069 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 7069 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 7069 R-RNO-8937419 https://reactome.org/PathwayBrowser/#/R-RNO-8937419 CBR3 reduces DOX to DOXOL IEA Rattus norvegicus 7069 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 7069 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 7069 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 7069 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 7069 R-SSC-8937419 https://reactome.org/PathwayBrowser/#/R-SSC-8937419 CBR3 reduces DOX to DOXOL IEA Sus scrofa 7069 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 7069 R-XTR-8937419 https://reactome.org/PathwayBrowser/#/R-XTR-8937419 CBR3 reduces DOX to DOXOL IEA Xenopus tropicalis 7071 R-BTA-9716947 https://reactome.org/PathwayBrowser/#/R-BTA-9716947 ESR1 binds ESR1 agonists IEA Bos taurus 7071 R-DME-9716947 https://reactome.org/PathwayBrowser/#/R-DME-9716947 ESR1 binds ESR1 agonists IEA Drosophila melanogaster 7071 R-DRE-9716947 https://reactome.org/PathwayBrowser/#/R-DRE-9716947 ESR1 binds ESR1 agonists IEA Danio rerio 7071 R-GGA-9716947 https://reactome.org/PathwayBrowser/#/R-GGA-9716947 ESR1 binds ESR1 agonists IEA Gallus gallus 7071 R-HSA-9716947 https://reactome.org/PathwayBrowser/#/R-HSA-9716947 ESR1 binds ESR1 agonists TAS Homo sapiens 7071 R-MMU-9716947 https://reactome.org/PathwayBrowser/#/R-MMU-9716947 ESR1 binds ESR1 agonists IEA Mus musculus 7071 R-RNO-9716947 https://reactome.org/PathwayBrowser/#/R-RNO-9716947 ESR1 binds ESR1 agonists IEA Rattus norvegicus 7071 R-SSC-9716947 https://reactome.org/PathwayBrowser/#/R-SSC-9716947 ESR1 binds ESR1 agonists IEA Sus scrofa 7071 R-XTR-9716947 https://reactome.org/PathwayBrowser/#/R-XTR-9716947 ESR1 binds ESR1 agonists IEA Xenopus tropicalis 7073 R-BTA-9707353 https://reactome.org/PathwayBrowser/#/R-BTA-9707353 CYP19A1 binds Aromatase inhibitors IEA Bos taurus 7073 R-CEL-9707353 https://reactome.org/PathwayBrowser/#/R-CEL-9707353 CYP19A1 binds Aromatase inhibitors IEA Caenorhabditis elegans 7073 R-CFA-9707353 https://reactome.org/PathwayBrowser/#/R-CFA-9707353 CYP19A1 binds Aromatase inhibitors IEA Canis familiaris 7073 R-DME-9707353 https://reactome.org/PathwayBrowser/#/R-DME-9707353 CYP19A1 binds Aromatase inhibitors IEA Drosophila melanogaster 7073 R-DRE-9707353 https://reactome.org/PathwayBrowser/#/R-DRE-9707353 CYP19A1 binds Aromatase inhibitors IEA Danio rerio 7073 R-GGA-9707353 https://reactome.org/PathwayBrowser/#/R-GGA-9707353 CYP19A1 binds Aromatase inhibitors IEA Gallus gallus 7073 R-HSA-9707353 https://reactome.org/PathwayBrowser/#/R-HSA-9707353 CYP19A1 binds Aromatase inhibitors TAS Homo sapiens 7073 R-MMU-9707353 https://reactome.org/PathwayBrowser/#/R-MMU-9707353 CYP19A1 binds Aromatase inhibitors IEA Mus musculus 7073 R-RNO-9707353 https://reactome.org/PathwayBrowser/#/R-RNO-9707353 CYP19A1 binds Aromatase inhibitors IEA Rattus norvegicus 7073 R-SSC-9707353 https://reactome.org/PathwayBrowser/#/R-SSC-9707353 CYP19A1 binds Aromatase inhibitors IEA Sus scrofa 7073 R-XTR-9707353 https://reactome.org/PathwayBrowser/#/R-XTR-9707353 CYP19A1 binds Aromatase inhibitors IEA Xenopus tropicalis 7074 R-BTA-9692738 https://reactome.org/PathwayBrowser/#/R-BTA-9692738 HRH2 binds HRH2 antagonists IEA Bos taurus 7074 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 7074 R-CEL-9692738 https://reactome.org/PathwayBrowser/#/R-CEL-9692738 HRH2 binds HRH2 antagonists IEA Caenorhabditis elegans 7074 R-CFA-9692738 https://reactome.org/PathwayBrowser/#/R-CFA-9692738 HRH2 binds HRH2 antagonists IEA Canis familiaris 7074 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 7074 R-DME-9692738 https://reactome.org/PathwayBrowser/#/R-DME-9692738 HRH2 binds HRH2 antagonists IEA Drosophila melanogaster 7074 R-DRE-9692738 https://reactome.org/PathwayBrowser/#/R-DRE-9692738 HRH2 binds HRH2 antagonists IEA Danio rerio 7074 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 7074 R-GGA-9692738 https://reactome.org/PathwayBrowser/#/R-GGA-9692738 HRH2 binds HRH2 antagonists IEA Gallus gallus 7074 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 7074 R-HSA-9692738 https://reactome.org/PathwayBrowser/#/R-HSA-9692738 HRH2 binds HRH2 antagonists TAS Homo sapiens 7074 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 7074 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 7074 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 7074 R-MMU-9692738 https://reactome.org/PathwayBrowser/#/R-MMU-9692738 HRH2 binds HRH2 antagonists IEA Mus musculus 7074 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 7074 R-RNO-9692738 https://reactome.org/PathwayBrowser/#/R-RNO-9692738 HRH2 binds HRH2 antagonists IEA Rattus norvegicus 7074 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 7074 R-SSC-9692738 https://reactome.org/PathwayBrowser/#/R-SSC-9692738 HRH2 binds HRH2 antagonists IEA Sus scrofa 7074 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 7074 R-XTR-9692738 https://reactome.org/PathwayBrowser/#/R-XTR-9692738 HRH2 binds HRH2 antagonists IEA Xenopus tropicalis 7076 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7076 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7076 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7076 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7076 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7076 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7076 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7076 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7076 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7076 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7076 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7076 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7076 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7076 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7076 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7076 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7076 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7076 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7076 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7076 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7076 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7076 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7077 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7077 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7077 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7077 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7077 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7077 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7077 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7077 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7077 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7077 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7077 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7077 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7077 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7077 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7077 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7077 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7077 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7077 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7077 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7077 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7077 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7077 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7078 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7078 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7078 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7078 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7078 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7078 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7078 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7078 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7078 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7078 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7078 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7078 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7078 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7078 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7078 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7078 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7078 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7078 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7078 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7078 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7078 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7078 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7079 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7079 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7079 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7079 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7079 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7079 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7079 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7079 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7079 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7079 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7079 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7079 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7079 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7079 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7079 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7079 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7079 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7079 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7079 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7079 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7079 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7079 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7080 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7080 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7080 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7080 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7080 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7080 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7080 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7080 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7080 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7080 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7080 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7080 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7080 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7080 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7080 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7080 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7080 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7080 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7080 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7080 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7080 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7080 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7088 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 7088 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 7088 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7088 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7088 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 7088 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 7088 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7088 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7088 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 7088 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 7088 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7088 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7088 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7088 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7088 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 7088 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 7088 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7088 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7088 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 7088 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 7088 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7088 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7088 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 7088 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 7088 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7088 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7088 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 7088 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 7088 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7088 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7088 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 7088 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 7088 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7088 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7088 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 7088 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 7088 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 7088 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 7088 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7088 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7088 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7088 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7089 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 709 R-HSA-9911462 https://reactome.org/PathwayBrowser/#/R-HSA-9911462 Aminoglycoside antibiotics bind Kpn 16S rRNA TAS Homo sapiens 709 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 709 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 7092 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 7092 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 7092 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 7092 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 7092 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 7092 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 7092 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 7092 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 7092 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 7092 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 7092 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 7095 R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 7095 R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 7095 R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 7095 R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 7095 R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 7095 R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 7095 R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 7095 R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 7095 R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 7095 R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 7095 R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 7096 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 7096 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 7096 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7096 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7096 R-BTA-9757578 https://reactome.org/PathwayBrowser/#/R-BTA-9757578 ALB binds PREDN IEA Bos taurus 7096 R-BTA-9757688 https://reactome.org/PathwayBrowser/#/R-BTA-9757688 SERPINA6 binds PREDN IEA Bos taurus 7096 R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 7096 R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 7096 R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 7096 R-BTA-9759259 https://reactome.org/PathwayBrowser/#/R-BTA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Bos taurus 7096 R-BTA-9759454 https://reactome.org/PathwayBrowser/#/R-BTA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Bos taurus 7096 R-BTA-9759461 https://reactome.org/PathwayBrowser/#/R-BTA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Bos taurus 7096 R-BTA-9762345 https://reactome.org/PathwayBrowser/#/R-BTA-9762345 PREDN:ALB dissociates IEA Bos taurus 7096 R-CEL-9757688 https://reactome.org/PathwayBrowser/#/R-CEL-9757688 SERPINA6 binds PREDN IEA Caenorhabditis elegans 7096 R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 7096 R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 7096 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 7096 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 7096 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7096 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7096 R-CFA-9757578 https://reactome.org/PathwayBrowser/#/R-CFA-9757578 ALB binds PREDN IEA Canis familiaris 7096 R-CFA-9757688 https://reactome.org/PathwayBrowser/#/R-CFA-9757688 SERPINA6 binds PREDN IEA Canis familiaris 7096 R-CFA-9757706 https://reactome.org/PathwayBrowser/#/R-CFA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Canis familiaris 7096 R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 7096 R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 7096 R-CFA-9759259 https://reactome.org/PathwayBrowser/#/R-CFA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Canis familiaris 7096 R-CFA-9759454 https://reactome.org/PathwayBrowser/#/R-CFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Canis familiaris 7096 R-CFA-9759461 https://reactome.org/PathwayBrowser/#/R-CFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Canis familiaris 7096 R-CFA-9762345 https://reactome.org/PathwayBrowser/#/R-CFA-9762345 PREDN:ALB dissociates IEA Canis familiaris 7096 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 7096 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 7096 R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 7096 R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 7096 R-DDI-9759454 https://reactome.org/PathwayBrowser/#/R-DDI-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Dictyostelium discoideum 7096 R-DDI-9759461 https://reactome.org/PathwayBrowser/#/R-DDI-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Dictyostelium discoideum 7096 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7096 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7096 R-DME-9757688 https://reactome.org/PathwayBrowser/#/R-DME-9757688 SERPINA6 binds PREDN IEA Drosophila melanogaster 7096 R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 7096 R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 7096 R-DME-9759259 https://reactome.org/PathwayBrowser/#/R-DME-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Drosophila melanogaster 7096 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7096 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7096 R-DRE-9757688 https://reactome.org/PathwayBrowser/#/R-DRE-9757688 SERPINA6 binds PREDN IEA Danio rerio 7096 R-DRE-9757706 https://reactome.org/PathwayBrowser/#/R-DRE-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Danio rerio 7096 R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 7096 R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 7096 R-DRE-9759259 https://reactome.org/PathwayBrowser/#/R-DRE-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Danio rerio 7096 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 7096 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 7096 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7096 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7096 R-GGA-9757578 https://reactome.org/PathwayBrowser/#/R-GGA-9757578 ALB binds PREDN IEA Gallus gallus 7096 R-GGA-9757706 https://reactome.org/PathwayBrowser/#/R-GGA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Gallus gallus 7096 R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 7096 R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 7096 R-GGA-9759259 https://reactome.org/PathwayBrowser/#/R-GGA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Gallus gallus 7096 R-GGA-9759454 https://reactome.org/PathwayBrowser/#/R-GGA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Gallus gallus 7096 R-GGA-9759461 https://reactome.org/PathwayBrowser/#/R-GGA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Gallus gallus 7096 R-GGA-9762345 https://reactome.org/PathwayBrowser/#/R-GGA-9762345 PREDN:ALB dissociates IEA Gallus gallus 7096 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 7096 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 7096 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7096 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7096 R-HSA-9757540 https://reactome.org/PathwayBrowser/#/R-HSA-9757540 PREDN,PREDL diffuse into GI cells TAS Homo sapiens 7096 R-HSA-9757578 https://reactome.org/PathwayBrowser/#/R-HSA-9757578 ALB binds PREDN TAS Homo sapiens 7096 R-HSA-9757688 https://reactome.org/PathwayBrowser/#/R-HSA-9757688 SERPINA6 binds PREDN TAS Homo sapiens 7096 R-HSA-9757698 https://reactome.org/PathwayBrowser/#/R-HSA-9757698 PREDN,PREDL diffuse into hepatic cells TAS Homo sapiens 7096 R-HSA-9757706 https://reactome.org/PathwayBrowser/#/R-HSA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell TAS Homo sapiens 7096 R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 7096 R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 7096 R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 7096 R-HSA-9759259 https://reactome.org/PathwayBrowser/#/R-HSA-9759259 HSD11B2 dehydrogenates PREDL to PREDN TAS Homo sapiens 7096 R-HSA-9759445 https://reactome.org/PathwayBrowser/#/R-HSA-9759445 PREDN,PREDL diffuse into kidney cells TAS Homo sapiens 7096 R-HSA-9759454 https://reactome.org/PathwayBrowser/#/R-HSA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells TAS Homo sapiens 7096 R-HSA-9759461 https://reactome.org/PathwayBrowser/#/R-HSA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells TAS Homo sapiens 7096 R-HSA-9762345 https://reactome.org/PathwayBrowser/#/R-HSA-9762345 PREDN:ALB dissociates TAS Homo sapiens 7096 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 7096 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 7096 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7096 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7096 R-MMU-9757578 https://reactome.org/PathwayBrowser/#/R-MMU-9757578 ALB binds PREDN IEA Mus musculus 7096 R-MMU-9757688 https://reactome.org/PathwayBrowser/#/R-MMU-9757688 SERPINA6 binds PREDN IEA Mus musculus 7096 R-MMU-9757706 https://reactome.org/PathwayBrowser/#/R-MMU-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Mus musculus 7096 R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 7096 R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 7096 R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 7096 R-MMU-9759259 https://reactome.org/PathwayBrowser/#/R-MMU-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Mus musculus 7096 R-MMU-9759454 https://reactome.org/PathwayBrowser/#/R-MMU-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Mus musculus 7096 R-MMU-9759461 https://reactome.org/PathwayBrowser/#/R-MMU-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Mus musculus 7096 R-MMU-9762345 https://reactome.org/PathwayBrowser/#/R-MMU-9762345 PREDN:ALB dissociates IEA Mus musculus 7096 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 7096 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 7096 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7096 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7096 R-PFA-9759454 https://reactome.org/PathwayBrowser/#/R-PFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Plasmodium falciparum 7096 R-PFA-9759461 https://reactome.org/PathwayBrowser/#/R-PFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Plasmodium falciparum 7096 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 7096 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 7096 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7096 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7096 R-RNO-9757578 https://reactome.org/PathwayBrowser/#/R-RNO-9757578 ALB binds PREDN IEA Rattus norvegicus 7096 R-RNO-9757688 https://reactome.org/PathwayBrowser/#/R-RNO-9757688 SERPINA6 binds PREDN IEA Rattus norvegicus 7096 R-RNO-9757706 https://reactome.org/PathwayBrowser/#/R-RNO-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Rattus norvegicus 7096 R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 7096 R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 7096 R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 7096 R-RNO-9759259 https://reactome.org/PathwayBrowser/#/R-RNO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Rattus norvegicus 7096 R-RNO-9759454 https://reactome.org/PathwayBrowser/#/R-RNO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Rattus norvegicus 7096 R-RNO-9759461 https://reactome.org/PathwayBrowser/#/R-RNO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Rattus norvegicus 7096 R-RNO-9762345 https://reactome.org/PathwayBrowser/#/R-RNO-9762345 PREDN:ALB dissociates IEA Rattus norvegicus 7096 R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 7096 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 7096 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 7096 R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 7096 R-SPO-9759259 https://reactome.org/PathwayBrowser/#/R-SPO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Schizosaccharomyces pombe 7096 R-SPO-9759454 https://reactome.org/PathwayBrowser/#/R-SPO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Schizosaccharomyces pombe 7096 R-SPO-9759461 https://reactome.org/PathwayBrowser/#/R-SPO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Schizosaccharomyces pombe 7096 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 7096 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 7096 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7096 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7096 R-SSC-9757578 https://reactome.org/PathwayBrowser/#/R-SSC-9757578 ALB binds PREDN IEA Sus scrofa 7096 R-SSC-9757688 https://reactome.org/PathwayBrowser/#/R-SSC-9757688 SERPINA6 binds PREDN IEA Sus scrofa 7096 R-SSC-9757706 https://reactome.org/PathwayBrowser/#/R-SSC-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Sus scrofa 7096 R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 7096 R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 7096 R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 7096 R-SSC-9759259 https://reactome.org/PathwayBrowser/#/R-SSC-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Sus scrofa 7096 R-SSC-9759454 https://reactome.org/PathwayBrowser/#/R-SSC-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Sus scrofa 7096 R-SSC-9759461 https://reactome.org/PathwayBrowser/#/R-SSC-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Sus scrofa 7096 R-SSC-9762345 https://reactome.org/PathwayBrowser/#/R-SSC-9762345 PREDN:ALB dissociates IEA Sus scrofa 7096 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7096 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7096 R-XTR-9757578 https://reactome.org/PathwayBrowser/#/R-XTR-9757578 ALB binds PREDN IEA Xenopus tropicalis 7096 R-XTR-9757688 https://reactome.org/PathwayBrowser/#/R-XTR-9757688 SERPINA6 binds PREDN IEA Xenopus tropicalis 7096 R-XTR-9757706 https://reactome.org/PathwayBrowser/#/R-XTR-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Xenopus tropicalis 7096 R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 7096 R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 7096 R-XTR-9759259 https://reactome.org/PathwayBrowser/#/R-XTR-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Xenopus tropicalis 7096 R-XTR-9762345 https://reactome.org/PathwayBrowser/#/R-XTR-9762345 PREDN:ALB dissociates IEA Xenopus tropicalis 7099 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7099 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7099 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7099 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7099 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7099 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7099 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7099 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7099 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7099 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7099 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7099 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7099 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7099 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7099 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7099 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7099 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7099 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7099 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7099 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7099 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7099 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7100 R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 7100 R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 7100 R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 7100 R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 7100 R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 7100 R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 7100 R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 7100 R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 7100 R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 7100 R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 7100 R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 7107 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 7107 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 7107 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 7107 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 7107 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 7107 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 7107 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 7107 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 7107 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 7107 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 7107 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 7107 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 7107 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 7107 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 7107 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 7107 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 7107 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 7107 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 7107 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 7107 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 7107 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 7107 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 7107 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 7107 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 7107 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 7107 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 7107 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 7107 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 7107 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 7107 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 7107 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 7107 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 7107 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 7107 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 7107 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 7107 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 7107 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 7112 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7113 R-HSA-1606345 https://reactome.org/PathwayBrowser/#/R-HSA-1606345 Recruitment of IRF3 to activated ZBP1:TBK1 IEA Homo sapiens 7113 R-HSA-9679819 https://reactome.org/PathwayBrowser/#/R-HSA-9679819 TBK1 binds amlexanox TAS Homo sapiens 7114 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 7114 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 7114 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 7114 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 7114 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 7114 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 7114 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 7114 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 7114 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 7114 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 7117 R-BTA-9626914 https://reactome.org/PathwayBrowser/#/R-BTA-9626914 α2-agonists bind ADRA2A,B,C IEA Bos taurus 7117 R-CEL-9626914 https://reactome.org/PathwayBrowser/#/R-CEL-9626914 α2-agonists bind ADRA2A,B,C IEA Caenorhabditis elegans 7117 R-CFA-9626914 https://reactome.org/PathwayBrowser/#/R-CFA-9626914 α2-agonists bind ADRA2A,B,C IEA Canis familiaris 7117 R-DME-9626914 https://reactome.org/PathwayBrowser/#/R-DME-9626914 α2-agonists bind ADRA2A,B,C IEA Drosophila melanogaster 7117 R-DRE-9626914 https://reactome.org/PathwayBrowser/#/R-DRE-9626914 α2-agonists bind ADRA2A,B,C IEA Danio rerio 7117 R-GGA-9626914 https://reactome.org/PathwayBrowser/#/R-GGA-9626914 α2-agonists bind ADRA2A,B,C IEA Gallus gallus 7117 R-HSA-9626914 https://reactome.org/PathwayBrowser/#/R-HSA-9626914 α2-agonists bind ADRA2A,B,C TAS Homo sapiens 7117 R-MMU-9626914 https://reactome.org/PathwayBrowser/#/R-MMU-9626914 α2-agonists bind ADRA2A,B,C IEA Mus musculus 7117 R-RNO-9626914 https://reactome.org/PathwayBrowser/#/R-RNO-9626914 α2-agonists bind ADRA2A,B,C IEA Rattus norvegicus 7117 R-SSC-9626914 https://reactome.org/PathwayBrowser/#/R-SSC-9626914 α2-agonists bind ADRA2A,B,C IEA Sus scrofa 7117 R-XTR-9626914 https://reactome.org/PathwayBrowser/#/R-XTR-9626914 α2-agonists bind ADRA2A,B,C IEA Xenopus tropicalis 7120 R-BTA-9748996 https://reactome.org/PathwayBrowser/#/R-BTA-9748996 GST dimers cleave AZA to 6MP IEA Bos taurus 7120 R-CFA-9748996 https://reactome.org/PathwayBrowser/#/R-CFA-9748996 GST dimers cleave AZA to 6MP IEA Canis familiaris 7120 R-DDI-9748996 https://reactome.org/PathwayBrowser/#/R-DDI-9748996 GST dimers cleave AZA to 6MP IEA Dictyostelium discoideum 7120 R-DRE-9748996 https://reactome.org/PathwayBrowser/#/R-DRE-9748996 GST dimers cleave AZA to 6MP IEA Danio rerio 7120 R-GGA-9748996 https://reactome.org/PathwayBrowser/#/R-GGA-9748996 GST dimers cleave AZA to 6MP IEA Gallus gallus 7120 R-HSA-9748996 https://reactome.org/PathwayBrowser/#/R-HSA-9748996 GST dimers cleave AZA to 6MP TAS Homo sapiens 7120 R-HSA-9751051 https://reactome.org/PathwayBrowser/#/R-HSA-9751051 GSH cleaves AZA to 6MP TAS Homo sapiens 7120 R-MMU-9748996 https://reactome.org/PathwayBrowser/#/R-MMU-9748996 GST dimers cleave AZA to 6MP IEA Mus musculus 7120 R-PFA-9748996 https://reactome.org/PathwayBrowser/#/R-PFA-9748996 GST dimers cleave AZA to 6MP IEA Plasmodium falciparum 7120 R-RNO-9748996 https://reactome.org/PathwayBrowser/#/R-RNO-9748996 GST dimers cleave AZA to 6MP IEA Rattus norvegicus 7120 R-SSC-9748996 https://reactome.org/PathwayBrowser/#/R-SSC-9748996 GST dimers cleave AZA to 6MP IEA Sus scrofa 7120 R-XTR-9748996 https://reactome.org/PathwayBrowser/#/R-XTR-9748996 GST dimers cleave AZA to 6MP IEA Xenopus tropicalis 7121 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7121 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7121 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7121 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7121 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 7121 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7121 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7121 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7121 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7122 R-BTA-9725706 https://reactome.org/PathwayBrowser/#/R-BTA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Bos taurus 7122 R-CEL-9725706 https://reactome.org/PathwayBrowser/#/R-CEL-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Caenorhabditis elegans 7122 R-CFA-9725706 https://reactome.org/PathwayBrowser/#/R-CFA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Canis familiaris 7122 R-DME-9725706 https://reactome.org/PathwayBrowser/#/R-DME-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Drosophila melanogaster 7122 R-HSA-9725706 https://reactome.org/PathwayBrowser/#/R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors TAS Homo sapiens 7122 R-MMU-9725706 https://reactome.org/PathwayBrowser/#/R-MMU-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Mus musculus 7122 R-RNO-9725706 https://reactome.org/PathwayBrowser/#/R-RNO-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Rattus norvegicus 7122 R-SSC-9725706 https://reactome.org/PathwayBrowser/#/R-SSC-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Sus scrofa 7122 R-XTR-9725706 https://reactome.org/PathwayBrowser/#/R-XTR-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Xenopus tropicalis 7124 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 7124 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 7124 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 7124 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 7124 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 7124 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 7124 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 7124 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 7124 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 7124 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 7124 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 7124 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 7124 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 7124 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 7124 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 7124 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 7124 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 7124 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 7125 R-BTA-9725706 https://reactome.org/PathwayBrowser/#/R-BTA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Bos taurus 7125 R-CEL-9725706 https://reactome.org/PathwayBrowser/#/R-CEL-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Caenorhabditis elegans 7125 R-CFA-9725706 https://reactome.org/PathwayBrowser/#/R-CFA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Canis familiaris 7125 R-DME-9725706 https://reactome.org/PathwayBrowser/#/R-DME-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Drosophila melanogaster 7125 R-HSA-9725706 https://reactome.org/PathwayBrowser/#/R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors TAS Homo sapiens 7125 R-MMU-9725706 https://reactome.org/PathwayBrowser/#/R-MMU-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Mus musculus 7125 R-RNO-9725706 https://reactome.org/PathwayBrowser/#/R-RNO-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Rattus norvegicus 7125 R-SSC-9725706 https://reactome.org/PathwayBrowser/#/R-SSC-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Sus scrofa 7125 R-XTR-9725706 https://reactome.org/PathwayBrowser/#/R-XTR-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Xenopus tropicalis 7128 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 7128 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 7128 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 7128 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 7128 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 7128 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 7128 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 7128 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 7128 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 7128 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 7128 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 7131 R-BTA-9677320 https://reactome.org/PathwayBrowser/#/R-BTA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Bos taurus 7131 R-CFA-9677320 https://reactome.org/PathwayBrowser/#/R-CFA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Canis familiaris 7131 R-DRE-9677320 https://reactome.org/PathwayBrowser/#/R-DRE-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Danio rerio 7131 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus 7131 R-HSA-9677320 https://reactome.org/PathwayBrowser/#/R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors TAS Homo sapiens 7131 R-MMU-9677320 https://reactome.org/PathwayBrowser/#/R-MMU-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Mus musculus 7131 R-RNO-9677320 https://reactome.org/PathwayBrowser/#/R-RNO-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Rattus norvegicus 7131 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa 7131 R-XTR-9677320 https://reactome.org/PathwayBrowser/#/R-XTR-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Xenopus tropicalis 7135 R-BTA-9714580 https://reactome.org/PathwayBrowser/#/R-BTA-9714580 SLC6A3 binds DRIs IEA Bos taurus 7135 R-CEL-9714580 https://reactome.org/PathwayBrowser/#/R-CEL-9714580 SLC6A3 binds DRIs IEA Caenorhabditis elegans 7135 R-CFA-9714580 https://reactome.org/PathwayBrowser/#/R-CFA-9714580 SLC6A3 binds DRIs IEA Canis familiaris 7135 R-DME-9714580 https://reactome.org/PathwayBrowser/#/R-DME-9714580 SLC6A3 binds DRIs IEA Drosophila melanogaster 7135 R-DRE-9714580 https://reactome.org/PathwayBrowser/#/R-DRE-9714580 SLC6A3 binds DRIs IEA Danio rerio 7135 R-HSA-9714580 https://reactome.org/PathwayBrowser/#/R-HSA-9714580 SLC6A3 binds DRIs TAS Homo sapiens 7135 R-MMU-9714580 https://reactome.org/PathwayBrowser/#/R-MMU-9714580 SLC6A3 binds DRIs IEA Mus musculus 7135 R-PFA-9714580 https://reactome.org/PathwayBrowser/#/R-PFA-9714580 SLC6A3 binds DRIs IEA Plasmodium falciparum 7135 R-RNO-9714580 https://reactome.org/PathwayBrowser/#/R-RNO-9714580 SLC6A3 binds DRIs IEA Rattus norvegicus 7135 R-SSC-9714580 https://reactome.org/PathwayBrowser/#/R-SSC-9714580 SLC6A3 binds DRIs IEA Sus scrofa 7135 R-XTR-9714580 https://reactome.org/PathwayBrowser/#/R-XTR-9714580 SLC6A3 binds DRIs IEA Xenopus tropicalis 7141 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 7141 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 7141 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 7141 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 7141 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 7141 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 7141 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 7141 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 7141 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 7141 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 7141 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 7141 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 7141 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 7141 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 7141 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 7141 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 7141 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 7141 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 7143 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7148 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 7148 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 7148 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 7148 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 7148 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 7148 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 7148 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 7148 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 7148 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 7148 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 7151 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7151 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7151 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7151 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7151 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7151 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7151 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7151 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7154 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7157 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7157 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7157 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7157 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7157 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 7157 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7157 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7157 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7157 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7158 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7158 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7158 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7158 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7158 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7158 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7158 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7158 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7158 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7158 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7158 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7158 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7162 R-BTA-9709109 https://reactome.org/PathwayBrowser/#/R-BTA-9709109 DHFR dimer binds DHFR inhibitors IEA Bos taurus 7162 R-CEL-9709109 https://reactome.org/PathwayBrowser/#/R-CEL-9709109 DHFR dimer binds DHFR inhibitors IEA Caenorhabditis elegans 7162 R-CFA-9709109 https://reactome.org/PathwayBrowser/#/R-CFA-9709109 DHFR dimer binds DHFR inhibitors IEA Canis familiaris 7162 R-DDI-9709109 https://reactome.org/PathwayBrowser/#/R-DDI-9709109 DHFR dimer binds DHFR inhibitors IEA Dictyostelium discoideum 7162 R-DME-9709109 https://reactome.org/PathwayBrowser/#/R-DME-9709109 DHFR dimer binds DHFR inhibitors IEA Drosophila melanogaster 7162 R-DRE-9709109 https://reactome.org/PathwayBrowser/#/R-DRE-9709109 DHFR dimer binds DHFR inhibitors IEA Danio rerio 7162 R-GGA-9709109 https://reactome.org/PathwayBrowser/#/R-GGA-9709109 DHFR dimer binds DHFR inhibitors IEA Gallus gallus 7162 R-HSA-9709109 https://reactome.org/PathwayBrowser/#/R-HSA-9709109 DHFR dimer binds DHFR inhibitors TAS Homo sapiens 7162 R-MMU-9709109 https://reactome.org/PathwayBrowser/#/R-MMU-9709109 DHFR dimer binds DHFR inhibitors IEA Mus musculus 7162 R-RNO-9709109 https://reactome.org/PathwayBrowser/#/R-RNO-9709109 DHFR dimer binds DHFR inhibitors IEA Rattus norvegicus 7162 R-SCE-9709109 https://reactome.org/PathwayBrowser/#/R-SCE-9709109 DHFR dimer binds DHFR inhibitors IEA Saccharomyces cerevisiae 7162 R-SPO-9709109 https://reactome.org/PathwayBrowser/#/R-SPO-9709109 DHFR dimer binds DHFR inhibitors IEA Schizosaccharomyces pombe 7162 R-SSC-9709109 https://reactome.org/PathwayBrowser/#/R-SSC-9709109 DHFR dimer binds DHFR inhibitors IEA Sus scrofa 7168 R-BTA-9693324 https://reactome.org/PathwayBrowser/#/R-BTA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Bos taurus 7168 R-CFA-9693324 https://reactome.org/PathwayBrowser/#/R-CFA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Canis familiaris 7168 R-GGA-9693324 https://reactome.org/PathwayBrowser/#/R-GGA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Gallus gallus 7168 R-HSA-9693324 https://reactome.org/PathwayBrowser/#/R-HSA-9693324 Disulfiram covalently modifies Cys191 in GSDMD TAS Homo sapiens 7168 R-MMU-9693324 https://reactome.org/PathwayBrowser/#/R-MMU-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Mus musculus 7168 R-RNO-9693324 https://reactome.org/PathwayBrowser/#/R-RNO-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Rattus norvegicus 7168 R-SSC-9693324 https://reactome.org/PathwayBrowser/#/R-SSC-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Sus scrofa 7170 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 7170 R-BTA-9617370 https://reactome.org/PathwayBrowser/#/R-BTA-9617370 α1-antagonists bind ADRA1A,B,D IEA Bos taurus 7170 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 7170 R-CEL-9617370 https://reactome.org/PathwayBrowser/#/R-CEL-9617370 α1-antagonists bind ADRA1A,B,D IEA Caenorhabditis elegans 7170 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 7170 R-CFA-9617370 https://reactome.org/PathwayBrowser/#/R-CFA-9617370 α1-antagonists bind ADRA1A,B,D IEA Canis familiaris 7170 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 7170 R-DME-9617370 https://reactome.org/PathwayBrowser/#/R-DME-9617370 α1-antagonists bind ADRA1A,B,D IEA Drosophila melanogaster 7170 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 7170 R-DRE-9617370 https://reactome.org/PathwayBrowser/#/R-DRE-9617370 α1-antagonists bind ADRA1A,B,D IEA Danio rerio 7170 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 7170 R-GGA-9617370 https://reactome.org/PathwayBrowser/#/R-GGA-9617370 α1-antagonists bind ADRA1A,B,D IEA Gallus gallus 7170 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 7170 R-HSA-9617370 https://reactome.org/PathwayBrowser/#/R-HSA-9617370 α1-antagonists bind ADRA1A,B,D TAS Homo sapiens 7170 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 7170 R-MMU-9617370 https://reactome.org/PathwayBrowser/#/R-MMU-9617370 α1-antagonists bind ADRA1A,B,D IEA Mus musculus 7170 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 7170 R-RNO-9617370 https://reactome.org/PathwayBrowser/#/R-RNO-9617370 α1-antagonists bind ADRA1A,B,D IEA Rattus norvegicus 7170 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 7170 R-SSC-9617370 https://reactome.org/PathwayBrowser/#/R-SSC-9617370 α1-antagonists bind ADRA1A,B,D IEA Sus scrofa 7170 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 7170 R-XTR-9617370 https://reactome.org/PathwayBrowser/#/R-XTR-9617370 α1-antagonists bind ADRA1A,B,D IEA Xenopus tropicalis 7176 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7176 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7176 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7176 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7176 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7176 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7176 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7176 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7177 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7177 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7177 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7177 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7177 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7177 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7177 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7177 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7177 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7177 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7177 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7177 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7178 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 7178 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 7178 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 7178 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 7178 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 7178 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 7178 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 7178 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 7178 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 7178 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 7178 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 7178 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 7178 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 7178 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 7178 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 7178 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 7178 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 7178 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 7178 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 7178 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 7178 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 7178 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 7178 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 7178 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 7178 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 7178 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 7178 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 7178 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 7178 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 7178 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 7178 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 7178 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 7178 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 7178 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 7178 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 7178 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 7178 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 7182 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 7182 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 7182 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 7182 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 7182 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 7185 R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 7185 R-BTA-2309779 https://reactome.org/PathwayBrowser/#/R-BTA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Bos taurus 7185 R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 7185 R-CFA-2309779 https://reactome.org/PathwayBrowser/#/R-CFA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Canis familiaris 7185 R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 7185 R-DRE-2309779 https://reactome.org/PathwayBrowser/#/R-DRE-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Danio rerio 7185 R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 7185 R-GGA-2309779 https://reactome.org/PathwayBrowser/#/R-GGA-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Gallus gallus 7185 R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 7185 R-HSA-2309779 https://reactome.org/PathwayBrowser/#/R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors TAS Homo sapiens 7185 R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 7185 R-MMU-2309779 https://reactome.org/PathwayBrowser/#/R-MMU-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Mus musculus 7185 R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 7185 R-RNO-2309779 https://reactome.org/PathwayBrowser/#/R-RNO-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Rattus norvegicus 7185 R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 7185 R-SSC-2309779 https://reactome.org/PathwayBrowser/#/R-SSC-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Sus scrofa 7185 R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 7185 R-XTR-2309779 https://reactome.org/PathwayBrowser/#/R-XTR-2309779 PTGS2 dimer binds PTGS2 inhibitors IEA Xenopus tropicalis 7186 R-BTA-9734475 https://reactome.org/PathwayBrowser/#/R-BTA-9734475 PPARA binds fibrates IEA Bos taurus 7186 R-CFA-9734475 https://reactome.org/PathwayBrowser/#/R-CFA-9734475 PPARA binds fibrates IEA Canis familiaris 7186 R-DME-9734475 https://reactome.org/PathwayBrowser/#/R-DME-9734475 PPARA binds fibrates IEA Drosophila melanogaster 7186 R-DRE-9734475 https://reactome.org/PathwayBrowser/#/R-DRE-9734475 PPARA binds fibrates IEA Danio rerio 7186 R-GGA-9734475 https://reactome.org/PathwayBrowser/#/R-GGA-9734475 PPARA binds fibrates IEA Gallus gallus 7186 R-HSA-9734475 https://reactome.org/PathwayBrowser/#/R-HSA-9734475 PPARA binds fibrates TAS Homo sapiens 7186 R-MMU-9734475 https://reactome.org/PathwayBrowser/#/R-MMU-9734475 PPARA binds fibrates IEA Mus musculus 7186 R-RNO-9734475 https://reactome.org/PathwayBrowser/#/R-RNO-9734475 PPARA binds fibrates IEA Rattus norvegicus 7186 R-SSC-9734475 https://reactome.org/PathwayBrowser/#/R-SSC-9734475 PPARA binds fibrates IEA Sus scrofa 7186 R-XTR-9734475 https://reactome.org/PathwayBrowser/#/R-XTR-9734475 PPARA binds fibrates IEA Xenopus tropicalis 7189 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7189 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7189 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7189 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7189 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7189 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7189 R-HSA-9679780 https://reactome.org/PathwayBrowser/#/R-HSA-9679780 SIGMAR1 binds fluvoxamine TAS Homo sapiens 7189 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7189 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7189 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7189 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7189 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7189 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7191 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 7191 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 7191 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 7191 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 7191 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 7191 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 7191 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 7191 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 7191 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 7191 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 7198 R-BTA-187895 https://reactome.org/PathwayBrowser/#/R-BTA-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Bos taurus 7198 R-BTA-9679029 https://reactome.org/PathwayBrowser/#/R-BTA-9679029 C-ter TLR7 dimer binds HCQ IEA Bos taurus 7198 R-BTA-9679045 https://reactome.org/PathwayBrowser/#/R-BTA-9679045 C-ter TLR9 dimer binds HCQ IEA Bos taurus 7198 R-CFA-187895 https://reactome.org/PathwayBrowser/#/R-CFA-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Canis familiaris 7198 R-CFA-9679029 https://reactome.org/PathwayBrowser/#/R-CFA-9679029 C-ter TLR7 dimer binds HCQ IEA Canis familiaris 7198 R-CFA-9679045 https://reactome.org/PathwayBrowser/#/R-CFA-9679045 C-ter TLR9 dimer binds HCQ IEA Canis familiaris 7198 R-GGA-9679029 https://reactome.org/PathwayBrowser/#/R-GGA-9679029 C-ter TLR7 dimer binds HCQ IEA Gallus gallus 7198 R-HSA-167983 https://reactome.org/PathwayBrowser/#/R-HSA-167983 C-ter TLR7 dimer binds TLR7, TLR8 ligands TAS Homo sapiens 7198 R-HSA-187895 https://reactome.org/PathwayBrowser/#/R-HSA-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 TAS Homo sapiens 7198 R-HSA-9679029 https://reactome.org/PathwayBrowser/#/R-HSA-9679029 C-ter TLR7 dimer binds HCQ TAS Homo sapiens 7198 R-HSA-9679045 https://reactome.org/PathwayBrowser/#/R-HSA-9679045 C-ter TLR9 dimer binds HCQ TAS Homo sapiens 7198 R-HSA-9683467 https://reactome.org/PathwayBrowser/#/R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ TAS Homo sapiens 7198 R-HSA-9683478 https://reactome.org/PathwayBrowser/#/R-HSA-9683478 CQ, HCQ diffuses from cytosol to endocytic vesicle lumen TAS Homo sapiens 7198 R-HSA-9755765 https://reactome.org/PathwayBrowser/#/R-HSA-9755765 C-ter TLR7 dimer binds SARS-CoV-2 GU-rich ssRNA TAS Homo sapiens 7198 R-HSA-9836773 https://reactome.org/PathwayBrowser/#/R-HSA-9836773 RSV ssRNA binds C-ter TLR7 dimer TAS Homo sapiens 7198 R-MMU-187895 https://reactome.org/PathwayBrowser/#/R-MMU-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Mus musculus 7198 R-MMU-9679029 https://reactome.org/PathwayBrowser/#/R-MMU-9679029 C-ter TLR7 dimer binds HCQ IEA Mus musculus 7198 R-MMU-9679045 https://reactome.org/PathwayBrowser/#/R-MMU-9679045 C-ter TLR9 dimer binds HCQ IEA Mus musculus 7198 R-RNO-187895 https://reactome.org/PathwayBrowser/#/R-RNO-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Rattus norvegicus 7198 R-RNO-9679029 https://reactome.org/PathwayBrowser/#/R-RNO-9679029 C-ter TLR7 dimer binds HCQ IEA Rattus norvegicus 7198 R-RNO-9679045 https://reactome.org/PathwayBrowser/#/R-RNO-9679045 C-ter TLR9 dimer binds HCQ IEA Rattus norvegicus 7198 R-SSC-187895 https://reactome.org/PathwayBrowser/#/R-SSC-187895 Engulfed CpG DNA binds to endosomal C-ter TLR9 IEA Sus scrofa 7198 R-SSC-9679029 https://reactome.org/PathwayBrowser/#/R-SSC-9679029 C-ter TLR7 dimer binds HCQ IEA Sus scrofa 7198 R-SSC-9679045 https://reactome.org/PathwayBrowser/#/R-SSC-9679045 C-ter TLR9 dimer binds HCQ IEA Sus scrofa 7198 R-XTR-9679029 https://reactome.org/PathwayBrowser/#/R-XTR-9679029 C-ter TLR7 dimer binds HCQ IEA Xenopus tropicalis 7199 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7199 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7199 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7199 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7199 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 7199 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7199 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7199 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7199 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7200 R-BTA-9613264 https://reactome.org/PathwayBrowser/#/R-BTA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Bos taurus 7200 R-CFA-9613264 https://reactome.org/PathwayBrowser/#/R-CFA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Canis familiaris 7200 R-GGA-9613264 https://reactome.org/PathwayBrowser/#/R-GGA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Gallus gallus 7200 R-HSA-9613264 https://reactome.org/PathwayBrowser/#/R-HSA-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE TAS Homo sapiens 7200 R-MMU-9613264 https://reactome.org/PathwayBrowser/#/R-MMU-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Mus musculus 7200 R-RNO-9613264 https://reactome.org/PathwayBrowser/#/R-RNO-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Rattus norvegicus 7200 R-SSC-9613264 https://reactome.org/PathwayBrowser/#/R-SSC-9613264 Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE IEA Sus scrofa 7201 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7202 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 7202 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 7202 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 7202 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 7202 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 7202 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 7202 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 7202 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 7202 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 7202 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 7204 R-BTA-9677917 https://reactome.org/PathwayBrowser/#/R-BTA-9677917 MAOA inhibitors bind MAOA:FAD IEA Bos taurus 7204 R-CFA-9677917 https://reactome.org/PathwayBrowser/#/R-CFA-9677917 MAOA inhibitors bind MAOA:FAD IEA Canis familiaris 7204 R-DDI-9677917 https://reactome.org/PathwayBrowser/#/R-DDI-9677917 MAOA inhibitors bind MAOA:FAD IEA Dictyostelium discoideum 7204 R-GGA-9677917 https://reactome.org/PathwayBrowser/#/R-GGA-9677917 MAOA inhibitors bind MAOA:FAD IEA Gallus gallus 7204 R-HSA-9677917 https://reactome.org/PathwayBrowser/#/R-HSA-9677917 MAOA inhibitors bind MAOA:FAD TAS Homo sapiens 7204 R-MMU-9677917 https://reactome.org/PathwayBrowser/#/R-MMU-9677917 MAOA inhibitors bind MAOA:FAD IEA Mus musculus 7204 R-RNO-9677917 https://reactome.org/PathwayBrowser/#/R-RNO-9677917 MAOA inhibitors bind MAOA:FAD IEA Rattus norvegicus 7204 R-SSC-9677917 https://reactome.org/PathwayBrowser/#/R-SSC-9677917 MAOA inhibitors bind MAOA:FAD IEA Sus scrofa 7206 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7206 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7206 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7206 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7206 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7206 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7206 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7206 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7207 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 7207 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 7207 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 7207 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 7207 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 7207 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 7207 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 7207 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 7207 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 7207 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 7207 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 7207 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 7207 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 7207 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 7207 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 7207 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 7207 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 7207 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 7207 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 7207 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 7207 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 7207 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 7207 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 7207 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 7207 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 7207 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 7207 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 7207 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 7207 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 7207 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 7207 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 7207 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 7207 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 7207 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 7207 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 7207 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 7207 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 7208 R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 7208 R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 7208 R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 7208 R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 7208 R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 7208 R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 7208 R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 7214 R-ECO-9750080 https://reactome.org/PathwayBrowser/#/R-ECO-9750080 Lomustine produces interstrand crosslinks in E. coli DNA TAS Escherichia coli 7214 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7216 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7216 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7216 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7216 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7216 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 7216 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7216 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7216 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7216 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7218 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7219 R-BTA-9707186 https://reactome.org/PathwayBrowser/#/R-BTA-9707186 ALOX5 binds ALOX5 inhibitors IEA Bos taurus 7219 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 7219 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 7219 R-CFA-9707186 https://reactome.org/PathwayBrowser/#/R-CFA-9707186 ALOX5 binds ALOX5 inhibitors IEA Canis familiaris 7219 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 7219 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 7219 R-DDI-9707186 https://reactome.org/PathwayBrowser/#/R-DDI-9707186 ALOX5 binds ALOX5 inhibitors IEA Dictyostelium discoideum 7219 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 7219 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 7219 R-GGA-9707186 https://reactome.org/PathwayBrowser/#/R-GGA-9707186 ALOX5 binds ALOX5 inhibitors IEA Gallus gallus 7219 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 7219 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 7219 R-HSA-9707186 https://reactome.org/PathwayBrowser/#/R-HSA-9707186 ALOX5 binds ALOX5 inhibitors TAS Homo sapiens 7219 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 7219 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 7219 R-MMU-9707186 https://reactome.org/PathwayBrowser/#/R-MMU-9707186 ALOX5 binds ALOX5 inhibitors IEA Mus musculus 7219 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 7219 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 7219 R-RNO-9707186 https://reactome.org/PathwayBrowser/#/R-RNO-9707186 ALOX5 binds ALOX5 inhibitors IEA Rattus norvegicus 7219 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 7219 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 7219 R-SSC-9707186 https://reactome.org/PathwayBrowser/#/R-SSC-9707186 ALOX5 binds ALOX5 inhibitors IEA Sus scrofa 7219 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 7219 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 7219 R-XTR-9707186 https://reactome.org/PathwayBrowser/#/R-XTR-9707186 ALOX5 binds ALOX5 inhibitors IEA Xenopus tropicalis 7219 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 7219 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 7220 R-BTA-9677320 https://reactome.org/PathwayBrowser/#/R-BTA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Bos taurus 7220 R-CFA-9677320 https://reactome.org/PathwayBrowser/#/R-CFA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Canis familiaris 7220 R-DRE-9677320 https://reactome.org/PathwayBrowser/#/R-DRE-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Danio rerio 7220 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus 7220 R-HSA-9677320 https://reactome.org/PathwayBrowser/#/R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors TAS Homo sapiens 7220 R-MMU-9677320 https://reactome.org/PathwayBrowser/#/R-MMU-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Mus musculus 7220 R-RNO-9677320 https://reactome.org/PathwayBrowser/#/R-RNO-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Rattus norvegicus 7220 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa 7220 R-XTR-9677320 https://reactome.org/PathwayBrowser/#/R-XTR-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Xenopus tropicalis 7226 R-BTA-9748951 https://reactome.org/PathwayBrowser/#/R-BTA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Bos taurus 7226 R-BTA-9748983 https://reactome.org/PathwayBrowser/#/R-BTA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Bos taurus 7226 R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 7226 R-BTA-9748996 https://reactome.org/PathwayBrowser/#/R-BTA-9748996 GST dimers cleave AZA to 6MP IEA Bos taurus 7226 R-BTA-9751024 https://reactome.org/PathwayBrowser/#/R-BTA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Bos taurus 7226 R-BTA-9751037 https://reactome.org/PathwayBrowser/#/R-BTA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Bos taurus 7226 R-CEL-9748951 https://reactome.org/PathwayBrowser/#/R-CEL-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Caenorhabditis elegans 7226 R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 7226 R-CEL-9751024 https://reactome.org/PathwayBrowser/#/R-CEL-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Caenorhabditis elegans 7226 R-CEL-9751037 https://reactome.org/PathwayBrowser/#/R-CEL-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 7226 R-CFA-9748951 https://reactome.org/PathwayBrowser/#/R-CFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Canis familiaris 7226 R-CFA-9748983 https://reactome.org/PathwayBrowser/#/R-CFA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Canis familiaris 7226 R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 7226 R-CFA-9748996 https://reactome.org/PathwayBrowser/#/R-CFA-9748996 GST dimers cleave AZA to 6MP IEA Canis familiaris 7226 R-CFA-9751024 https://reactome.org/PathwayBrowser/#/R-CFA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Canis familiaris 7226 R-CFA-9751037 https://reactome.org/PathwayBrowser/#/R-CFA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Canis familiaris 7226 R-DDI-9748951 https://reactome.org/PathwayBrowser/#/R-DDI-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Dictyostelium discoideum 7226 R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 7226 R-DDI-9748996 https://reactome.org/PathwayBrowser/#/R-DDI-9748996 GST dimers cleave AZA to 6MP IEA Dictyostelium discoideum 7226 R-DDI-9751024 https://reactome.org/PathwayBrowser/#/R-DDI-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Dictyostelium discoideum 7226 R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 7226 R-DME-9751024 https://reactome.org/PathwayBrowser/#/R-DME-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Drosophila melanogaster 7226 R-DME-9751037 https://reactome.org/PathwayBrowser/#/R-DME-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 7226 R-DRE-9748951 https://reactome.org/PathwayBrowser/#/R-DRE-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Danio rerio 7226 R-DRE-9748983 https://reactome.org/PathwayBrowser/#/R-DRE-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Danio rerio 7226 R-DRE-9748996 https://reactome.org/PathwayBrowser/#/R-DRE-9748996 GST dimers cleave AZA to 6MP IEA Danio rerio 7226 R-DRE-9751024 https://reactome.org/PathwayBrowser/#/R-DRE-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Danio rerio 7226 R-GGA-9748951 https://reactome.org/PathwayBrowser/#/R-GGA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Gallus gallus 7226 R-GGA-9748983 https://reactome.org/PathwayBrowser/#/R-GGA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Gallus gallus 7226 R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 7226 R-GGA-9748996 https://reactome.org/PathwayBrowser/#/R-GGA-9748996 GST dimers cleave AZA to 6MP IEA Gallus gallus 7226 R-GGA-9751037 https://reactome.org/PathwayBrowser/#/R-GGA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Gallus gallus 7226 R-HSA-9748951 https://reactome.org/PathwayBrowser/#/R-HSA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP TAS Homo sapiens 7226 R-HSA-9748983 https://reactome.org/PathwayBrowser/#/R-HSA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP TAS Homo sapiens 7226 R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 7226 R-HSA-9748996 https://reactome.org/PathwayBrowser/#/R-HSA-9748996 GST dimers cleave AZA to 6MP TAS Homo sapiens 7226 R-HSA-9751024 https://reactome.org/PathwayBrowser/#/R-HSA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol TAS Homo sapiens 7226 R-HSA-9751037 https://reactome.org/PathwayBrowser/#/R-HSA-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol TAS Homo sapiens 7226 R-HSA-9751051 https://reactome.org/PathwayBrowser/#/R-HSA-9751051 GSH cleaves AZA to 6MP TAS Homo sapiens 7226 R-MMU-9748951 https://reactome.org/PathwayBrowser/#/R-MMU-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Mus musculus 7226 R-MMU-9748983 https://reactome.org/PathwayBrowser/#/R-MMU-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Mus musculus 7226 R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 7226 R-MMU-9748996 https://reactome.org/PathwayBrowser/#/R-MMU-9748996 GST dimers cleave AZA to 6MP IEA Mus musculus 7226 R-MMU-9751024 https://reactome.org/PathwayBrowser/#/R-MMU-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Mus musculus 7226 R-MMU-9751037 https://reactome.org/PathwayBrowser/#/R-MMU-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Mus musculus 7226 R-PFA-9748951 https://reactome.org/PathwayBrowser/#/R-PFA-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Plasmodium falciparum 7226 R-PFA-9748996 https://reactome.org/PathwayBrowser/#/R-PFA-9748996 GST dimers cleave AZA to 6MP IEA Plasmodium falciparum 7226 R-PFA-9751024 https://reactome.org/PathwayBrowser/#/R-PFA-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Plasmodium falciparum 7226 R-RNO-9748951 https://reactome.org/PathwayBrowser/#/R-RNO-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Rattus norvegicus 7226 R-RNO-9748983 https://reactome.org/PathwayBrowser/#/R-RNO-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Rattus norvegicus 7226 R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 7226 R-RNO-9748996 https://reactome.org/PathwayBrowser/#/R-RNO-9748996 GST dimers cleave AZA to 6MP IEA Rattus norvegicus 7226 R-RNO-9751024 https://reactome.org/PathwayBrowser/#/R-RNO-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Rattus norvegicus 7226 R-RNO-9751037 https://reactome.org/PathwayBrowser/#/R-RNO-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Rattus norvegicus 7226 R-SSC-9748951 https://reactome.org/PathwayBrowser/#/R-SSC-9748951 HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP IEA Sus scrofa 7226 R-SSC-9748983 https://reactome.org/PathwayBrowser/#/R-SSC-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Sus scrofa 7226 R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 7226 R-SSC-9748996 https://reactome.org/PathwayBrowser/#/R-SSC-9748996 GST dimers cleave AZA to 6MP IEA Sus scrofa 7226 R-SSC-9751024 https://reactome.org/PathwayBrowser/#/R-SSC-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Sus scrofa 7226 R-SSC-9751037 https://reactome.org/PathwayBrowser/#/R-SSC-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Sus scrofa 7226 R-XTR-9748983 https://reactome.org/PathwayBrowser/#/R-XTR-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Xenopus tropicalis 7226 R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 7226 R-XTR-9748996 https://reactome.org/PathwayBrowser/#/R-XTR-9748996 GST dimers cleave AZA to 6MP IEA Xenopus tropicalis 7226 R-XTR-9751024 https://reactome.org/PathwayBrowser/#/R-XTR-9751024 SLC29A1,2 transport 6MP from extracellular region to cytosol IEA Xenopus tropicalis 7226 R-XTR-9751037 https://reactome.org/PathwayBrowser/#/R-XTR-9751037 SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 7227 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 7227 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 7227 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 7227 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 7227 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 7227 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 7227 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 7227 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 7227 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 7227 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 7227 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 7227 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 7227 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 7227 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 7227 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 7227 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 7227 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 7227 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 7227 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 7227 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 7236 R-BTA-9714580 https://reactome.org/PathwayBrowser/#/R-BTA-9714580 SLC6A3 binds DRIs IEA Bos taurus 7236 R-CEL-9714580 https://reactome.org/PathwayBrowser/#/R-CEL-9714580 SLC6A3 binds DRIs IEA Caenorhabditis elegans 7236 R-CFA-9714580 https://reactome.org/PathwayBrowser/#/R-CFA-9714580 SLC6A3 binds DRIs IEA Canis familiaris 7236 R-DME-9714580 https://reactome.org/PathwayBrowser/#/R-DME-9714580 SLC6A3 binds DRIs IEA Drosophila melanogaster 7236 R-DRE-9714580 https://reactome.org/PathwayBrowser/#/R-DRE-9714580 SLC6A3 binds DRIs IEA Danio rerio 7236 R-HSA-9714580 https://reactome.org/PathwayBrowser/#/R-HSA-9714580 SLC6A3 binds DRIs TAS Homo sapiens 7236 R-MMU-9714580 https://reactome.org/PathwayBrowser/#/R-MMU-9714580 SLC6A3 binds DRIs IEA Mus musculus 7236 R-PFA-9714580 https://reactome.org/PathwayBrowser/#/R-PFA-9714580 SLC6A3 binds DRIs IEA Plasmodium falciparum 7236 R-RNO-9714580 https://reactome.org/PathwayBrowser/#/R-RNO-9714580 SLC6A3 binds DRIs IEA Rattus norvegicus 7236 R-SSC-9714580 https://reactome.org/PathwayBrowser/#/R-SSC-9714580 SLC6A3 binds DRIs IEA Sus scrofa 7236 R-XTR-9714580 https://reactome.org/PathwayBrowser/#/R-XTR-9714580 SLC6A3 binds DRIs IEA Xenopus tropicalis 7237 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7237 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7237 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7237 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7237 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7237 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7237 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7237 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7242 R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 7242 R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 7246 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 7246 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 7246 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 7246 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 7246 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 7246 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 7246 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 7246 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 7246 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 7246 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 7246 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 7246 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 7246 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 7246 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 7246 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 7246 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 7246 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 7246 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 7246 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 7246 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 7246 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 7246 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 7246 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 7246 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 7246 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 7246 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 7246 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 7246 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 7246 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 7246 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 7246 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 7246 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 7246 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 7246 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 7246 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 7246 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 7246 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 7247 R-BTA-9678766 https://reactome.org/PathwayBrowser/#/R-BTA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Bos taurus 7247 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7247 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7247 R-CFA-9678766 https://reactome.org/PathwayBrowser/#/R-CFA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Canis familiaris 7247 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7247 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7247 R-DRE-9678766 https://reactome.org/PathwayBrowser/#/R-DRE-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Danio rerio 7247 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7247 R-GGA-9678766 https://reactome.org/PathwayBrowser/#/R-GGA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Gallus gallus 7247 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7247 R-HSA-9678766 https://reactome.org/PathwayBrowser/#/R-HSA-9678766 CYP3A4 binds CYP3A4 inhibitors TAS Homo sapiens 7247 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7247 R-MMU-9678766 https://reactome.org/PathwayBrowser/#/R-MMU-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Mus musculus 7247 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7247 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7247 R-RNO-9678766 https://reactome.org/PathwayBrowser/#/R-RNO-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Rattus norvegicus 7247 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7247 R-SSC-9678766 https://reactome.org/PathwayBrowser/#/R-SSC-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Sus scrofa 7247 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7247 R-XTR-9678766 https://reactome.org/PathwayBrowser/#/R-XTR-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Xenopus tropicalis 7247 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7248 R-BTA-9692738 https://reactome.org/PathwayBrowser/#/R-BTA-9692738 HRH2 binds HRH2 antagonists IEA Bos taurus 7248 R-CEL-9692738 https://reactome.org/PathwayBrowser/#/R-CEL-9692738 HRH2 binds HRH2 antagonists IEA Caenorhabditis elegans 7248 R-CFA-9692738 https://reactome.org/PathwayBrowser/#/R-CFA-9692738 HRH2 binds HRH2 antagonists IEA Canis familiaris 7248 R-DME-9692738 https://reactome.org/PathwayBrowser/#/R-DME-9692738 HRH2 binds HRH2 antagonists IEA Drosophila melanogaster 7248 R-DRE-9692738 https://reactome.org/PathwayBrowser/#/R-DRE-9692738 HRH2 binds HRH2 antagonists IEA Danio rerio 7248 R-GGA-9692738 https://reactome.org/PathwayBrowser/#/R-GGA-9692738 HRH2 binds HRH2 antagonists IEA Gallus gallus 7248 R-HSA-9692738 https://reactome.org/PathwayBrowser/#/R-HSA-9692738 HRH2 binds HRH2 antagonists TAS Homo sapiens 7248 R-MMU-9692738 https://reactome.org/PathwayBrowser/#/R-MMU-9692738 HRH2 binds HRH2 antagonists IEA Mus musculus 7248 R-RNO-9692738 https://reactome.org/PathwayBrowser/#/R-RNO-9692738 HRH2 binds HRH2 antagonists IEA Rattus norvegicus 7248 R-SSC-9692738 https://reactome.org/PathwayBrowser/#/R-SSC-9692738 HRH2 binds HRH2 antagonists IEA Sus scrofa 7248 R-XTR-9692738 https://reactome.org/PathwayBrowser/#/R-XTR-9692738 HRH2 binds HRH2 antagonists IEA Xenopus tropicalis 7252 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 7252 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 7252 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 7252 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 7252 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 7252 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 7252 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 7252 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 7252 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 7252 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 7252 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 7252 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 7252 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 7252 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 7252 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 7252 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 7252 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 7252 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 7257 R-CEL-9704248 https://reactome.org/PathwayBrowser/#/R-CEL-9704248 CHRM4 binds CHRM4 antagonists IEA Caenorhabditis elegans 7257 R-CFA-9704248 https://reactome.org/PathwayBrowser/#/R-CFA-9704248 CHRM4 binds CHRM4 antagonists IEA Canis familiaris 7257 R-DME-9704248 https://reactome.org/PathwayBrowser/#/R-DME-9704248 CHRM4 binds CHRM4 antagonists IEA Drosophila melanogaster 7257 R-GGA-9704248 https://reactome.org/PathwayBrowser/#/R-GGA-9704248 CHRM4 binds CHRM4 antagonists IEA Gallus gallus 7257 R-HSA-9704248 https://reactome.org/PathwayBrowser/#/R-HSA-9704248 CHRM4 binds CHRM4 antagonists TAS Homo sapiens 7257 R-MMU-9704248 https://reactome.org/PathwayBrowser/#/R-MMU-9704248 CHRM4 binds CHRM4 antagonists IEA Mus musculus 7257 R-RNO-9704248 https://reactome.org/PathwayBrowser/#/R-RNO-9704248 CHRM4 binds CHRM4 antagonists IEA Rattus norvegicus 7257 R-SSC-9704248 https://reactome.org/PathwayBrowser/#/R-SSC-9704248 CHRM4 binds CHRM4 antagonists IEA Sus scrofa 7257 R-XTR-9704248 https://reactome.org/PathwayBrowser/#/R-XTR-9704248 CHRM4 binds CHRM4 antagonists IEA Xenopus tropicalis 7259 R-CEL-9717841 https://reactome.org/PathwayBrowser/#/R-CEL-9717841 holo-FDPS dimer binds NBPs IEA Caenorhabditis elegans 7259 R-CFA-9717841 https://reactome.org/PathwayBrowser/#/R-CFA-9717841 holo-FDPS dimer binds NBPs IEA Canis familiaris 7259 R-DDI-9717841 https://reactome.org/PathwayBrowser/#/R-DDI-9717841 holo-FDPS dimer binds NBPs IEA Dictyostelium discoideum 7259 R-DME-9717841 https://reactome.org/PathwayBrowser/#/R-DME-9717841 holo-FDPS dimer binds NBPs IEA Drosophila melanogaster 7259 R-DRE-9717841 https://reactome.org/PathwayBrowser/#/R-DRE-9717841 holo-FDPS dimer binds NBPs IEA Danio rerio 7259 R-GGA-9717841 https://reactome.org/PathwayBrowser/#/R-GGA-9717841 holo-FDPS dimer binds NBPs IEA Gallus gallus 7259 R-HSA-9717841 https://reactome.org/PathwayBrowser/#/R-HSA-9717841 holo-FDPS dimer binds NBPs TAS Homo sapiens 7259 R-MMU-9717841 https://reactome.org/PathwayBrowser/#/R-MMU-9717841 holo-FDPS dimer binds NBPs IEA Mus musculus 7259 R-PFA-9717841 https://reactome.org/PathwayBrowser/#/R-PFA-9717841 holo-FDPS dimer binds NBPs IEA Plasmodium falciparum 7259 R-RNO-9717841 https://reactome.org/PathwayBrowser/#/R-RNO-9717841 holo-FDPS dimer binds NBPs IEA Rattus norvegicus 7259 R-SCE-9717841 https://reactome.org/PathwayBrowser/#/R-SCE-9717841 holo-FDPS dimer binds NBPs IEA Saccharomyces cerevisiae 7259 R-SPO-9717841 https://reactome.org/PathwayBrowser/#/R-SPO-9717841 holo-FDPS dimer binds NBPs IEA Schizosaccharomyces pombe 7259 R-SSC-9717841 https://reactome.org/PathwayBrowser/#/R-SSC-9717841 holo-FDPS dimer binds NBPs IEA Sus scrofa 7260 R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 7260 R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 7260 R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 7260 R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 7260 R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 7260 R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 7260 R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 7270 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 7270 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 7270 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 7270 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 7270 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 7270 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 7270 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 7270 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 7270 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 7270 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 7270 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 7270 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 7270 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 7270 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 7270 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 7270 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 7270 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 7270 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 7273 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 7273 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 7273 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 7273 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 7273 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 7273 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 7273 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 7273 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 7273 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 7273 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 7273 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 7273 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 7273 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 7273 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 7273 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 7273 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 7273 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 7273 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 7274 R-BTA-9725706 https://reactome.org/PathwayBrowser/#/R-BTA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Bos taurus 7274 R-CEL-9725706 https://reactome.org/PathwayBrowser/#/R-CEL-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Caenorhabditis elegans 7274 R-CFA-9725706 https://reactome.org/PathwayBrowser/#/R-CFA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Canis familiaris 7274 R-DME-9725706 https://reactome.org/PathwayBrowser/#/R-DME-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Drosophila melanogaster 7274 R-HSA-9725706 https://reactome.org/PathwayBrowser/#/R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors TAS Homo sapiens 7274 R-MMU-9725706 https://reactome.org/PathwayBrowser/#/R-MMU-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Mus musculus 7274 R-RNO-9725706 https://reactome.org/PathwayBrowser/#/R-RNO-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Rattus norvegicus 7274 R-SSC-9725706 https://reactome.org/PathwayBrowser/#/R-SSC-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Sus scrofa 7274 R-XTR-9725706 https://reactome.org/PathwayBrowser/#/R-XTR-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Xenopus tropicalis 7278 R-HSA-9730736 https://reactome.org/PathwayBrowser/#/R-HSA-9730736 Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA IEA Homo sapiens 7278 R-HSA-9730767 https://reactome.org/PathwayBrowser/#/R-HSA-9730767 Monofunctional chemotherapeutic alkylating drugs produce 7-methylguanine in dsDNA IEA Homo sapiens 7278 R-HSA-9732692 https://reactome.org/PathwayBrowser/#/R-HSA-9732692 Triazenes produce DNA damage in the form of O6-methylguanine IEA Homo sapiens 7278 R-RNO-9730878 https://reactome.org/PathwayBrowser/#/R-RNO-9730878 Procarbazine produces 7-methylguanine in dsDNA TAS Rattus norvegicus 7281 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 7281 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 7281 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 7281 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 7281 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 7281 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 7281 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 7281 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 7281 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 7281 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 7282 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7282 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7282 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7282 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7282 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7282 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7282 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7282 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7285 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7285 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7285 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7285 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7285 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7285 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7285 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7285 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7285 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7285 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7285 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7285 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7289 R-BTA-9725706 https://reactome.org/PathwayBrowser/#/R-BTA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Bos taurus 7289 R-CEL-9725706 https://reactome.org/PathwayBrowser/#/R-CEL-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Caenorhabditis elegans 7289 R-CFA-9725706 https://reactome.org/PathwayBrowser/#/R-CFA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Canis familiaris 7289 R-DME-9725706 https://reactome.org/PathwayBrowser/#/R-DME-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Drosophila melanogaster 7289 R-HSA-9725706 https://reactome.org/PathwayBrowser/#/R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors TAS Homo sapiens 7289 R-MMU-9725706 https://reactome.org/PathwayBrowser/#/R-MMU-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Mus musculus 7289 R-RNO-9725706 https://reactome.org/PathwayBrowser/#/R-RNO-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Rattus norvegicus 7289 R-SSC-9725706 https://reactome.org/PathwayBrowser/#/R-SSC-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Sus scrofa 7289 R-XTR-9725706 https://reactome.org/PathwayBrowser/#/R-XTR-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Xenopus tropicalis 729 R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 729 R-BTA-419426 https://reactome.org/PathwayBrowser/#/R-BTA-419426 Cannabinoid receptors can bind cannabinoids IEA Bos taurus 729 R-BTA-426032 https://reactome.org/PathwayBrowser/#/R-BTA-426032 DAG is metabolized by DAGL to 2-AG IEA Bos taurus 729 R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 729 R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 729 R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 729 R-CEL-426032 https://reactome.org/PathwayBrowser/#/R-CEL-426032 DAG is metabolized by DAGL to 2-AG IEA Caenorhabditis elegans 729 R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 729 R-CFA-419426 https://reactome.org/PathwayBrowser/#/R-CFA-419426 Cannabinoid receptors can bind cannabinoids IEA Canis familiaris 729 R-CFA-426032 https://reactome.org/PathwayBrowser/#/R-CFA-426032 DAG is metabolized by DAGL to 2-AG IEA Canis familiaris 729 R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 729 R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 729 R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 729 R-DDI-426032 https://reactome.org/PathwayBrowser/#/R-DDI-426032 DAG is metabolized by DAGL to 2-AG IEA Dictyostelium discoideum 729 R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 729 R-DME-426032 https://reactome.org/PathwayBrowser/#/R-DME-426032 DAG is metabolized by DAGL to 2-AG IEA Drosophila melanogaster 729 R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 729 R-DRE-419426 https://reactome.org/PathwayBrowser/#/R-DRE-419426 Cannabinoid receptors can bind cannabinoids IEA Danio rerio 729 R-DRE-426032 https://reactome.org/PathwayBrowser/#/R-DRE-426032 DAG is metabolized by DAGL to 2-AG IEA Danio rerio 729 R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 729 R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 729 R-GGA-419426 https://reactome.org/PathwayBrowser/#/R-GGA-419426 Cannabinoid receptors can bind cannabinoids IEA Gallus gallus 729 R-GGA-426032 https://reactome.org/PathwayBrowser/#/R-GGA-426032 DAG is metabolized by DAGL to 2-AG IEA Gallus gallus 729 R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 729 R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 729 R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 729 R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 729 R-HSA-419426 https://reactome.org/PathwayBrowser/#/R-HSA-419426 Cannabinoid receptors can bind cannabinoids TAS Homo sapiens 729 R-HSA-426032 https://reactome.org/PathwayBrowser/#/R-HSA-426032 DAG is metabolized by DAGL to 2-AG TAS Homo sapiens 729 R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 729 R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 729 R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 729 R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 729 R-MMU-419426 https://reactome.org/PathwayBrowser/#/R-MMU-419426 Cannabinoid receptors can bind cannabinoids IEA Mus musculus 729 R-MMU-426032 https://reactome.org/PathwayBrowser/#/R-MMU-426032 DAG is metabolized by DAGL to 2-AG IEA Mus musculus 729 R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 729 R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 729 R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 729 R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 729 R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 729 R-RNO-419426 https://reactome.org/PathwayBrowser/#/R-RNO-419426 Cannabinoid receptors can bind cannabinoids IEA Rattus norvegicus 729 R-RNO-426032 https://reactome.org/PathwayBrowser/#/R-RNO-426032 DAG is metabolized by DAGL to 2-AG IEA Rattus norvegicus 729 R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 729 R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 729 R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 729 R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 729 R-SSC-419426 https://reactome.org/PathwayBrowser/#/R-SSC-419426 Cannabinoid receptors can bind cannabinoids IEA Sus scrofa 729 R-SSC-426032 https://reactome.org/PathwayBrowser/#/R-SSC-426032 DAG is metabolized by DAGL to 2-AG IEA Sus scrofa 729 R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 729 R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 729 R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 729 R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 729 R-XTR-419426 https://reactome.org/PathwayBrowser/#/R-XTR-419426 Cannabinoid receptors can bind cannabinoids IEA Xenopus tropicalis 729 R-XTR-426032 https://reactome.org/PathwayBrowser/#/R-XTR-426032 DAG is metabolized by DAGL to 2-AG IEA Xenopus tropicalis 729 R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 729 R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 729 R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 7290 R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 7290 R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 7290 R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 7290 R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 7290 R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 7290 R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 7290 R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 7297 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 7297 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 7297 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 7297 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 7297 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 7297 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 7297 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 7297 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 7297 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 7297 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 7297 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 7297 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 7297 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 7297 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 7297 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 7297 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 7297 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 7297 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 7297 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 7297 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 7297 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 7297 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 7297 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 7297 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 7297 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 7297 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 7297 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 7297 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 7297 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 7297 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 7297 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 7297 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 7297 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 7297 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 7297 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 7297 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 7297 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 7298 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 7298 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 7298 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 7298 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 7298 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 7298 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 7298 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 7298 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 7298 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 7298 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 7298 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 7298 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 7298 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 7298 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 7298 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 7298 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 7298 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 7298 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 7299 R-BTA-9708104 https://reactome.org/PathwayBrowser/#/R-BTA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Bos taurus 7299 R-CFA-9708104 https://reactome.org/PathwayBrowser/#/R-CFA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Canis familiaris 7299 R-DME-9708104 https://reactome.org/PathwayBrowser/#/R-DME-9708104 PDE5A dimer binds PDE5A inhibitors IEA Drosophila melanogaster 7299 R-GGA-9708104 https://reactome.org/PathwayBrowser/#/R-GGA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Gallus gallus 7299 R-HSA-9708104 https://reactome.org/PathwayBrowser/#/R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors TAS Homo sapiens 7299 R-MMU-9708104 https://reactome.org/PathwayBrowser/#/R-MMU-9708104 PDE5A dimer binds PDE5A inhibitors IEA Mus musculus 7299 R-RNO-9708104 https://reactome.org/PathwayBrowser/#/R-RNO-9708104 PDE5A dimer binds PDE5A inhibitors IEA Rattus norvegicus 7299 R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa 7299 R-XTR-9708104 https://reactome.org/PathwayBrowser/#/R-XTR-9708104 PDE5A dimer binds PDE5A inhibitors IEA Xenopus tropicalis 7301 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 7301 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 7301 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 7301 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 7301 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 7301 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 7301 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 7301 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 7301 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 7301 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 7301 R-HSA-9730736 https://reactome.org/PathwayBrowser/#/R-HSA-9730736 Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA IEA Homo sapiens 7301 R-HSA-9730767 https://reactome.org/PathwayBrowser/#/R-HSA-9730767 Monofunctional chemotherapeutic alkylating drugs produce 7-methylguanine in dsDNA IEA Homo sapiens 7301 R-HSA-9732692 https://reactome.org/PathwayBrowser/#/R-HSA-9732692 Triazenes produce DNA damage in the form of O6-methylguanine IEA Homo sapiens 7301 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 7301 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 7301 R-MMU-9749883 https://reactome.org/PathwayBrowser/#/R-MMU-9749883 Temozolomide produces DNA damage in the form of O6-methylguanine in mouse dsDNA TAS Mus musculus 7301 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 7301 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 7301 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 7301 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 7301 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 7301 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 7301 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 7301 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 7302 R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 7302 R-BTA-9617370 https://reactome.org/PathwayBrowser/#/R-BTA-9617370 α1-antagonists bind ADRA1A,B,D IEA Bos taurus 7302 R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 7302 R-CEL-9617370 https://reactome.org/PathwayBrowser/#/R-CEL-9617370 α1-antagonists bind ADRA1A,B,D IEA Caenorhabditis elegans 7302 R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 7302 R-CFA-9617370 https://reactome.org/PathwayBrowser/#/R-CFA-9617370 α1-antagonists bind ADRA1A,B,D IEA Canis familiaris 7302 R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 7302 R-DME-9617370 https://reactome.org/PathwayBrowser/#/R-DME-9617370 α1-antagonists bind ADRA1A,B,D IEA Drosophila melanogaster 7302 R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 7302 R-DRE-9617370 https://reactome.org/PathwayBrowser/#/R-DRE-9617370 α1-antagonists bind ADRA1A,B,D IEA Danio rerio 7302 R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 7302 R-GGA-9617370 https://reactome.org/PathwayBrowser/#/R-GGA-9617370 α1-antagonists bind ADRA1A,B,D IEA Gallus gallus 7302 R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 7302 R-HSA-9617370 https://reactome.org/PathwayBrowser/#/R-HSA-9617370 α1-antagonists bind ADRA1A,B,D TAS Homo sapiens 7302 R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 7302 R-MMU-9617370 https://reactome.org/PathwayBrowser/#/R-MMU-9617370 α1-antagonists bind ADRA1A,B,D IEA Mus musculus 7302 R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 7302 R-RNO-9617370 https://reactome.org/PathwayBrowser/#/R-RNO-9617370 α1-antagonists bind ADRA1A,B,D IEA Rattus norvegicus 7302 R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 7302 R-SSC-9617370 https://reactome.org/PathwayBrowser/#/R-SSC-9617370 α1-antagonists bind ADRA1A,B,D IEA Sus scrofa 7302 R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 7302 R-XTR-9617370 https://reactome.org/PathwayBrowser/#/R-XTR-9617370 α1-antagonists bind ADRA1A,B,D IEA Xenopus tropicalis 7303 R-BTA-9707353 https://reactome.org/PathwayBrowser/#/R-BTA-9707353 CYP19A1 binds Aromatase inhibitors IEA Bos taurus 7303 R-CEL-9707353 https://reactome.org/PathwayBrowser/#/R-CEL-9707353 CYP19A1 binds Aromatase inhibitors IEA Caenorhabditis elegans 7303 R-CFA-9707353 https://reactome.org/PathwayBrowser/#/R-CFA-9707353 CYP19A1 binds Aromatase inhibitors IEA Canis familiaris 7303 R-DME-9707353 https://reactome.org/PathwayBrowser/#/R-DME-9707353 CYP19A1 binds Aromatase inhibitors IEA Drosophila melanogaster 7303 R-DRE-9707353 https://reactome.org/PathwayBrowser/#/R-DRE-9707353 CYP19A1 binds Aromatase inhibitors IEA Danio rerio 7303 R-GGA-9707353 https://reactome.org/PathwayBrowser/#/R-GGA-9707353 CYP19A1 binds Aromatase inhibitors IEA Gallus gallus 7303 R-HSA-9707353 https://reactome.org/PathwayBrowser/#/R-HSA-9707353 CYP19A1 binds Aromatase inhibitors TAS Homo sapiens 7303 R-MMU-9707353 https://reactome.org/PathwayBrowser/#/R-MMU-9707353 CYP19A1 binds Aromatase inhibitors IEA Mus musculus 7303 R-RNO-9707353 https://reactome.org/PathwayBrowser/#/R-RNO-9707353 CYP19A1 binds Aromatase inhibitors IEA Rattus norvegicus 7303 R-SSC-9707353 https://reactome.org/PathwayBrowser/#/R-SSC-9707353 CYP19A1 binds Aromatase inhibitors IEA Sus scrofa 7303 R-XTR-9707353 https://reactome.org/PathwayBrowser/#/R-XTR-9707353 CYP19A1 binds Aromatase inhibitors IEA Xenopus tropicalis 7307 R-BTA-417829 https://reactome.org/PathwayBrowser/#/R-BTA-417829 P2RY12 binds ADP IEA Bos taurus 7307 R-BTA-9611277 https://reactome.org/PathwayBrowser/#/R-BTA-9611277 P2RY12 binds P2RY12 antagonists IEA Bos taurus 7307 R-CFA-417829 https://reactome.org/PathwayBrowser/#/R-CFA-417829 P2RY12 binds ADP IEA Canis familiaris 7307 R-CFA-9611277 https://reactome.org/PathwayBrowser/#/R-CFA-9611277 P2RY12 binds P2RY12 antagonists IEA Canis familiaris 7307 R-DRE-417829 https://reactome.org/PathwayBrowser/#/R-DRE-417829 P2RY12 binds ADP IEA Danio rerio 7307 R-DRE-9611277 https://reactome.org/PathwayBrowser/#/R-DRE-9611277 P2RY12 binds P2RY12 antagonists IEA Danio rerio 7307 R-HSA-417829 https://reactome.org/PathwayBrowser/#/R-HSA-417829 P2RY12 binds ADP TAS Homo sapiens 7307 R-HSA-9611277 https://reactome.org/PathwayBrowser/#/R-HSA-9611277 P2RY12 binds P2RY12 antagonists TAS Homo sapiens 7307 R-MMU-417829 https://reactome.org/PathwayBrowser/#/R-MMU-417829 P2RY12 binds ADP IEA Mus musculus 7307 R-MMU-9611277 https://reactome.org/PathwayBrowser/#/R-MMU-9611277 P2RY12 binds P2RY12 antagonists IEA Mus musculus 7307 R-RNO-417829 https://reactome.org/PathwayBrowser/#/R-RNO-417829 P2RY12 binds ADP IEA Rattus norvegicus 7307 R-RNO-9611277 https://reactome.org/PathwayBrowser/#/R-RNO-9611277 P2RY12 binds P2RY12 antagonists IEA Rattus norvegicus 7307 R-SSC-417829 https://reactome.org/PathwayBrowser/#/R-SSC-417829 P2RY12 binds ADP IEA Sus scrofa 7307 R-SSC-9611277 https://reactome.org/PathwayBrowser/#/R-SSC-9611277 P2RY12 binds P2RY12 antagonists IEA Sus scrofa 7307 R-XTR-417829 https://reactome.org/PathwayBrowser/#/R-XTR-417829 P2RY12 binds ADP IEA Xenopus tropicalis 7307 R-XTR-9611277 https://reactome.org/PathwayBrowser/#/R-XTR-9611277 P2RY12 binds P2RY12 antagonists IEA Xenopus tropicalis 7314 R-BTA-9725706 https://reactome.org/PathwayBrowser/#/R-BTA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Bos taurus 7314 R-CEL-9725706 https://reactome.org/PathwayBrowser/#/R-CEL-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Caenorhabditis elegans 7314 R-CFA-9725706 https://reactome.org/PathwayBrowser/#/R-CFA-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Canis familiaris 7314 R-DME-9725706 https://reactome.org/PathwayBrowser/#/R-DME-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Drosophila melanogaster 7314 R-HSA-9725706 https://reactome.org/PathwayBrowser/#/R-HSA-9725706 SLC12A3 binds SLC12A3 inhibitors TAS Homo sapiens 7314 R-MMU-9725706 https://reactome.org/PathwayBrowser/#/R-MMU-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Mus musculus 7314 R-RNO-9725706 https://reactome.org/PathwayBrowser/#/R-RNO-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Rattus norvegicus 7314 R-SSC-9725706 https://reactome.org/PathwayBrowser/#/R-SSC-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Sus scrofa 7314 R-XTR-9725706 https://reactome.org/PathwayBrowser/#/R-XTR-9725706 SLC12A3 binds SLC12A3 inhibitors IEA Xenopus tropicalis 7316 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 7316 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 7316 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 7316 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 7316 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 7317 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7317 R-BTA-9714580 https://reactome.org/PathwayBrowser/#/R-BTA-9714580 SLC6A3 binds DRIs IEA Bos taurus 7317 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7317 R-CEL-9714580 https://reactome.org/PathwayBrowser/#/R-CEL-9714580 SLC6A3 binds DRIs IEA Caenorhabditis elegans 7317 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7317 R-CFA-9714580 https://reactome.org/PathwayBrowser/#/R-CFA-9714580 SLC6A3 binds DRIs IEA Canis familiaris 7317 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7317 R-DME-9714580 https://reactome.org/PathwayBrowser/#/R-DME-9714580 SLC6A3 binds DRIs IEA Drosophila melanogaster 7317 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7317 R-DRE-9714580 https://reactome.org/PathwayBrowser/#/R-DRE-9714580 SLC6A3 binds DRIs IEA Danio rerio 7317 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7317 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7317 R-HSA-9714580 https://reactome.org/PathwayBrowser/#/R-HSA-9714580 SLC6A3 binds DRIs TAS Homo sapiens 7317 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7317 R-MMU-9714580 https://reactome.org/PathwayBrowser/#/R-MMU-9714580 SLC6A3 binds DRIs IEA Mus musculus 7317 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7317 R-PFA-9714580 https://reactome.org/PathwayBrowser/#/R-PFA-9714580 SLC6A3 binds DRIs IEA Plasmodium falciparum 7317 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7317 R-RNO-9714580 https://reactome.org/PathwayBrowser/#/R-RNO-9714580 SLC6A3 binds DRIs IEA Rattus norvegicus 7317 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7317 R-SSC-9714580 https://reactome.org/PathwayBrowser/#/R-SSC-9714580 SLC6A3 binds DRIs IEA Sus scrofa 7317 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7317 R-XTR-9714580 https://reactome.org/PathwayBrowser/#/R-XTR-9714580 SLC6A3 binds DRIs IEA Xenopus tropicalis 7318 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7318 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7318 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7318 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7318 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7318 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7318 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7318 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7319 R-CEL-9704248 https://reactome.org/PathwayBrowser/#/R-CEL-9704248 CHRM4 binds CHRM4 antagonists IEA Caenorhabditis elegans 7319 R-CFA-9704248 https://reactome.org/PathwayBrowser/#/R-CFA-9704248 CHRM4 binds CHRM4 antagonists IEA Canis familiaris 7319 R-DME-9704248 https://reactome.org/PathwayBrowser/#/R-DME-9704248 CHRM4 binds CHRM4 antagonists IEA Drosophila melanogaster 7319 R-GGA-9704248 https://reactome.org/PathwayBrowser/#/R-GGA-9704248 CHRM4 binds CHRM4 antagonists IEA Gallus gallus 7319 R-HSA-9704248 https://reactome.org/PathwayBrowser/#/R-HSA-9704248 CHRM4 binds CHRM4 antagonists TAS Homo sapiens 7319 R-MMU-9704248 https://reactome.org/PathwayBrowser/#/R-MMU-9704248 CHRM4 binds CHRM4 antagonists IEA Mus musculus 7319 R-RNO-9704248 https://reactome.org/PathwayBrowser/#/R-RNO-9704248 CHRM4 binds CHRM4 antagonists IEA Rattus norvegicus 7319 R-SSC-9704248 https://reactome.org/PathwayBrowser/#/R-SSC-9704248 CHRM4 binds CHRM4 antagonists IEA Sus scrofa 7319 R-XTR-9704248 https://reactome.org/PathwayBrowser/#/R-XTR-9704248 CHRM4 binds CHRM4 antagonists IEA Xenopus tropicalis 7320 R-BTA-9708104 https://reactome.org/PathwayBrowser/#/R-BTA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Bos taurus 7320 R-CFA-9708104 https://reactome.org/PathwayBrowser/#/R-CFA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Canis familiaris 7320 R-DME-9708104 https://reactome.org/PathwayBrowser/#/R-DME-9708104 PDE5A dimer binds PDE5A inhibitors IEA Drosophila melanogaster 7320 R-GGA-9708104 https://reactome.org/PathwayBrowser/#/R-GGA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Gallus gallus 7320 R-HSA-9708104 https://reactome.org/PathwayBrowser/#/R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors TAS Homo sapiens 7320 R-MMU-9708104 https://reactome.org/PathwayBrowser/#/R-MMU-9708104 PDE5A dimer binds PDE5A inhibitors IEA Mus musculus 7320 R-RNO-9708104 https://reactome.org/PathwayBrowser/#/R-RNO-9708104 PDE5A dimer binds PDE5A inhibitors IEA Rattus norvegicus 7320 R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa 7320 R-XTR-9708104 https://reactome.org/PathwayBrowser/#/R-XTR-9708104 PDE5A dimer binds PDE5A inhibitors IEA Xenopus tropicalis 7321 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7321 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7321 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7321 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7321 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7321 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7321 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7321 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7321 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7321 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7321 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7321 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7327 R-HSA-9681169 https://reactome.org/PathwayBrowser/#/R-HSA-9681169 CRBN binds IMiDs TAS Homo sapiens 7331 R-HSA-9681169 https://reactome.org/PathwayBrowser/#/R-HSA-9681169 CRBN binds IMiDs TAS Homo sapiens 7335 R-BTA-388828 https://reactome.org/PathwayBrowser/#/R-BTA-388828 PD-1 binds B7DC and B7H1 IEA Bos taurus 7335 R-BTA-9679421 https://reactome.org/PathwayBrowser/#/R-BTA-9679421 PDCD1 binds PDCD1 inhibitors IEA Bos taurus 7335 R-BTA-9936162 https://reactome.org/PathwayBrowser/#/R-BTA-9936162 PD-1 binds PD-L1,PD-L2 IEA Bos taurus 7335 R-CFA-388828 https://reactome.org/PathwayBrowser/#/R-CFA-388828 PD-1 binds B7DC and B7H1 IEA Canis familiaris 7335 R-CFA-9679421 https://reactome.org/PathwayBrowser/#/R-CFA-9679421 PDCD1 binds PDCD1 inhibitors IEA Canis familiaris 7335 R-CFA-9936162 https://reactome.org/PathwayBrowser/#/R-CFA-9936162 PD-1 binds PD-L1,PD-L2 IEA Canis familiaris 7335 R-GGA-388828 https://reactome.org/PathwayBrowser/#/R-GGA-388828 PD-1 binds B7DC and B7H1 IEA Gallus gallus 7335 R-GGA-9679421 https://reactome.org/PathwayBrowser/#/R-GGA-9679421 PDCD1 binds PDCD1 inhibitors IEA Gallus gallus 7335 R-GGA-9936162 https://reactome.org/PathwayBrowser/#/R-GGA-9936162 PD-1 binds PD-L1,PD-L2 IEA Gallus gallus 7335 R-HSA-388828 https://reactome.org/PathwayBrowser/#/R-HSA-388828 PD-1 binds B7DC and B7H1 TAS Homo sapiens 7335 R-HSA-9679421 https://reactome.org/PathwayBrowser/#/R-HSA-9679421 PDCD1 binds PDCD1 inhibitors TAS Homo sapiens 7335 R-HSA-9936162 https://reactome.org/PathwayBrowser/#/R-HSA-9936162 PD-1 binds PD-L1,PD-L2 TAS Homo sapiens 7335 R-MMU-388828 https://reactome.org/PathwayBrowser/#/R-MMU-388828 PD-1 binds B7DC and B7H1 IEA Mus musculus 7335 R-MMU-9679421 https://reactome.org/PathwayBrowser/#/R-MMU-9679421 PDCD1 binds PDCD1 inhibitors IEA Mus musculus 7335 R-MMU-9936162 https://reactome.org/PathwayBrowser/#/R-MMU-9936162 PD-1 binds PD-L1,PD-L2 IEA Mus musculus 7335 R-RNO-388828 https://reactome.org/PathwayBrowser/#/R-RNO-388828 PD-1 binds B7DC and B7H1 IEA Rattus norvegicus 7335 R-RNO-9679421 https://reactome.org/PathwayBrowser/#/R-RNO-9679421 PDCD1 binds PDCD1 inhibitors IEA Rattus norvegicus 7335 R-RNO-9936162 https://reactome.org/PathwayBrowser/#/R-RNO-9936162 PD-1 binds PD-L1,PD-L2 IEA Rattus norvegicus 7335 R-SSC-388828 https://reactome.org/PathwayBrowser/#/R-SSC-388828 PD-1 binds B7DC and B7H1 IEA Sus scrofa 7335 R-SSC-9679421 https://reactome.org/PathwayBrowser/#/R-SSC-9679421 PDCD1 binds PDCD1 inhibitors IEA Sus scrofa 7335 R-SSC-9936162 https://reactome.org/PathwayBrowser/#/R-SSC-9936162 PD-1 binds PD-L1,PD-L2 IEA Sus scrofa 7343 R-GGA-9733403 https://reactome.org/PathwayBrowser/#/R-GGA-9733403 PCSK9 binds PCSK9 inhibitors IEA Gallus gallus 7343 R-HSA-9733403 https://reactome.org/PathwayBrowser/#/R-HSA-9733403 PCSK9 binds PCSK9 inhibitors TAS Homo sapiens 7343 R-MMU-9733403 https://reactome.org/PathwayBrowser/#/R-MMU-9733403 PCSK9 binds PCSK9 inhibitors IEA Mus musculus 7343 R-RNO-9733403 https://reactome.org/PathwayBrowser/#/R-RNO-9733403 PCSK9 binds PCSK9 inhibitors IEA Rattus norvegicus 7343 R-SCE-9733403 https://reactome.org/PathwayBrowser/#/R-SCE-9733403 PCSK9 binds PCSK9 inhibitors IEA Saccharomyces cerevisiae 7343 R-SPO-9733403 https://reactome.org/PathwayBrowser/#/R-SPO-9733403 PCSK9 binds PCSK9 inhibitors IEA Schizosaccharomyces pombe 7343 R-SSC-9733403 https://reactome.org/PathwayBrowser/#/R-SSC-9733403 PCSK9 binds PCSK9 inhibitors IEA Sus scrofa 7343 R-XTR-9733403 https://reactome.org/PathwayBrowser/#/R-XTR-9733403 PCSK9 binds PCSK9 inhibitors IEA Xenopus tropicalis 7348 R-HSA-9681169 https://reactome.org/PathwayBrowser/#/R-HSA-9681169 CRBN binds IMiDs TAS Homo sapiens 7351 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 7351 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7351 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 7351 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7351 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 7351 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7351 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 7351 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7351 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 7351 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7351 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 7351 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7351 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 7351 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7351 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 7351 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7351 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7351 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 7351 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7351 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7351 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 7351 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7352 R-BTA-9731393 https://reactome.org/PathwayBrowser/#/R-BTA-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Bos taurus 7352 R-CFA-9731393 https://reactome.org/PathwayBrowser/#/R-CFA-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Canis familiaris 7352 R-DRE-9731393 https://reactome.org/PathwayBrowser/#/R-DRE-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Danio rerio 7352 R-GGA-9731393 https://reactome.org/PathwayBrowser/#/R-GGA-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Gallus gallus 7352 R-HSA-9731393 https://reactome.org/PathwayBrowser/#/R-HSA-9731393 EDNRA, EDNRB bind non-selective ERAs TAS Homo sapiens 7352 R-MMU-9731393 https://reactome.org/PathwayBrowser/#/R-MMU-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Mus musculus 7352 R-RNO-9731393 https://reactome.org/PathwayBrowser/#/R-RNO-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Rattus norvegicus 7352 R-SSC-9731393 https://reactome.org/PathwayBrowser/#/R-SSC-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Sus scrofa 7352 R-XTR-9731393 https://reactome.org/PathwayBrowser/#/R-XTR-9731393 EDNRA, EDNRB bind non-selective ERAs IEA Xenopus tropicalis 7354 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 7354 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 7354 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 7354 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 7354 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 7354 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 7354 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 7354 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 7354 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 7354 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 7354 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 7355 R-BTA-9716913 https://reactome.org/PathwayBrowser/#/R-BTA-9716913 ESR1 binds ESR1 antagonists IEA Bos taurus 7355 R-DME-9716913 https://reactome.org/PathwayBrowser/#/R-DME-9716913 ESR1 binds ESR1 antagonists IEA Drosophila melanogaster 7355 R-DRE-9716913 https://reactome.org/PathwayBrowser/#/R-DRE-9716913 ESR1 binds ESR1 antagonists IEA Danio rerio 7355 R-GGA-9716913 https://reactome.org/PathwayBrowser/#/R-GGA-9716913 ESR1 binds ESR1 antagonists IEA Gallus gallus 7355 R-HSA-9716913 https://reactome.org/PathwayBrowser/#/R-HSA-9716913 ESR1 binds ESR1 antagonists TAS Homo sapiens 7355 R-MMU-9716913 https://reactome.org/PathwayBrowser/#/R-MMU-9716913 ESR1 binds ESR1 antagonists IEA Mus musculus 7355 R-RNO-9716913 https://reactome.org/PathwayBrowser/#/R-RNO-9716913 ESR1 binds ESR1 antagonists IEA Rattus norvegicus 7355 R-SSC-9716913 https://reactome.org/PathwayBrowser/#/R-SSC-9716913 ESR1 binds ESR1 antagonists IEA Sus scrofa 7355 R-XTR-9716913 https://reactome.org/PathwayBrowser/#/R-XTR-9716913 ESR1 binds ESR1 antagonists IEA Xenopus tropicalis 7359 R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 7359 R-BTA-9756183 https://reactome.org/PathwayBrowser/#/R-BTA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Bos taurus 7359 R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 7359 R-DDI-9756183 https://reactome.org/PathwayBrowser/#/R-DDI-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Dictyostelium discoideum 7359 R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 7359 R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 7359 R-GGA-9756183 https://reactome.org/PathwayBrowser/#/R-GGA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Gallus gallus 7359 R-HSA-9756150 https://reactome.org/PathwayBrowser/#/R-HSA-9756150 PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV IEA Homo sapiens 7359 R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 7359 R-HSA-9756183 https://reactome.org/PathwayBrowser/#/R-HSA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL TAS Homo sapiens 7359 R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 7359 R-MMU-9756183 https://reactome.org/PathwayBrowser/#/R-MMU-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Mus musculus 7359 R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 7359 R-RNO-9756183 https://reactome.org/PathwayBrowser/#/R-RNO-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Rattus norvegicus 7359 R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 7359 R-SSC-9756183 https://reactome.org/PathwayBrowser/#/R-SSC-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Sus scrofa 7359 R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 7367 R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 7367 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 7367 R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 7367 R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 7367 R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 7367 R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 7367 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 7367 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 7367 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 7367 R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 7367 R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 7367 R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 7367 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 7367 R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 7367 R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 7367 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 7367 R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 7367 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 7367 R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 7367 R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 7367 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 7367 R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 7367 R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 7372 R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 7372 R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 7372 R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 7372 R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 7372 R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 7372 R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 7372 R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 7372 R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 7372 R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 7372 R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 7372 R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 7379 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 7379 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 7379 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 7379 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 7379 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 7379 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 7379 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 7379 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 7379 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 7379 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 7379 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 7379 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 7379 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 7379 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 7379 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 7379 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 7379 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 7379 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 7379 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 7379 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 7379 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 7379 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 7379 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 7379 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 7379 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 7379 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 7379 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 7379 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 7379 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 7380 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 7380 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 7380 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 7380 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 7380 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 7380 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 7380 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 7380 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 7380 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 7380 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 7380 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 7380 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 7380 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 7380 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 7380 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 7380 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 7380 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 7380 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 7380 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 7380 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 7380 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 7380 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 7380 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 7380 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 7380 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 7380 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 7380 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 7380 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 7380 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 7382 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 7382 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 7382 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 7382 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 7382 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 7382 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 7382 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 7382 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 7382 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 7382 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 7382 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 7382 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 7382 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 7382 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 7382 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 7382 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 7382 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 7382 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 7382 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 7382 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 7382 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 7382 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 7382 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 7382 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 7382 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 7382 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 7382 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 7382 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 7382 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 7383 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 7383 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 7383 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 7383 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 7383 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 7383 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 7383 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 7383 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 7383 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 7383 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 7383 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 7383 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 7383 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 7383 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 7383 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 7383 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 7383 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 7383 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 7383 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 7383 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 7383 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 7383 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 7383 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 7383 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 7383 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 7383 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 7383 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 7383 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 7383 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 7386 R-BTA-9728664 https://reactome.org/PathwayBrowser/#/R-BTA-9728664 GLP1R binds GLP1R agonists IEA Bos taurus 7386 R-CFA-9728664 https://reactome.org/PathwayBrowser/#/R-CFA-9728664 GLP1R binds GLP1R agonists IEA Canis familiaris 7386 R-DRE-9728664 https://reactome.org/PathwayBrowser/#/R-DRE-9728664 GLP1R binds GLP1R agonists IEA Danio rerio 7386 R-HSA-9728664 https://reactome.org/PathwayBrowser/#/R-HSA-9728664 GLP1R binds GLP1R agonists TAS Homo sapiens 7386 R-MMU-9728664 https://reactome.org/PathwayBrowser/#/R-MMU-9728664 GLP1R binds GLP1R agonists IEA Mus musculus 7386 R-RNO-9728664 https://reactome.org/PathwayBrowser/#/R-RNO-9728664 GLP1R binds GLP1R agonists IEA Rattus norvegicus 7386 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa 7387 R-BTA-9728664 https://reactome.org/PathwayBrowser/#/R-BTA-9728664 GLP1R binds GLP1R agonists IEA Bos taurus 7387 R-CFA-9728664 https://reactome.org/PathwayBrowser/#/R-CFA-9728664 GLP1R binds GLP1R agonists IEA Canis familiaris 7387 R-DRE-9728664 https://reactome.org/PathwayBrowser/#/R-DRE-9728664 GLP1R binds GLP1R agonists IEA Danio rerio 7387 R-HSA-9728664 https://reactome.org/PathwayBrowser/#/R-HSA-9728664 GLP1R binds GLP1R agonists TAS Homo sapiens 7387 R-MMU-9728664 https://reactome.org/PathwayBrowser/#/R-MMU-9728664 GLP1R binds GLP1R agonists IEA Mus musculus 7387 R-RNO-9728664 https://reactome.org/PathwayBrowser/#/R-RNO-9728664 GLP1R binds GLP1R agonists IEA Rattus norvegicus 7387 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa 7397 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 7397 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 7397 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 7397 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 7397 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 7397 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 7397 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 7397 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 7397 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 7397 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 7397 R-HSA-9700658 https://reactome.org/PathwayBrowser/#/R-HSA-9700658 ceritinib-resistant ALK mutants don't bind ceritinib TAS Homo sapiens 7397 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 7397 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 7397 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 7397 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 7397 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 7397 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 7397 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 7399 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 7399 R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 7399 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 7399 R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 7399 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 7399 R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 7399 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 7399 R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 7399 R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 7399 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 7399 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 7399 R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 7399 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 7399 R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 7399 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 7399 R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 7399 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 7399 R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 7399 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 7399 R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 7399 R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 7401 R-BTA-9677320 https://reactome.org/PathwayBrowser/#/R-BTA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Bos taurus 7401 R-BTA-9716836 https://reactome.org/PathwayBrowser/#/R-BTA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Bos taurus 7401 R-BTA-9716838 https://reactome.org/PathwayBrowser/#/R-BTA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Bos taurus 7401 R-CFA-9677320 https://reactome.org/PathwayBrowser/#/R-CFA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Canis familiaris 7401 R-CFA-9716836 https://reactome.org/PathwayBrowser/#/R-CFA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Canis familiaris 7401 R-CFA-9716838 https://reactome.org/PathwayBrowser/#/R-CFA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Canis familiaris 7401 R-DRE-9677320 https://reactome.org/PathwayBrowser/#/R-DRE-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Danio rerio 7401 R-DRE-9716836 https://reactome.org/PathwayBrowser/#/R-DRE-9716836 PTGS2 dimer binds PTGS inhibitors IEA Danio rerio 7401 R-DRE-9716838 https://reactome.org/PathwayBrowser/#/R-DRE-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Danio rerio 7401 R-GGA-9677320 https://reactome.org/PathwayBrowser/#/R-GGA-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Gallus gallus 7401 R-GGA-9716836 https://reactome.org/PathwayBrowser/#/R-GGA-9716836 PTGS2 dimer binds PTGS inhibitors IEA Gallus gallus 7401 R-GGA-9716838 https://reactome.org/PathwayBrowser/#/R-GGA-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Gallus gallus 7401 R-HSA-9677320 https://reactome.org/PathwayBrowser/#/R-HSA-9677320 PTGS1 dimer binds PTGS1 Inhibitors TAS Homo sapiens 7401 R-HSA-9716836 https://reactome.org/PathwayBrowser/#/R-HSA-9716836 PTGS2 dimer binds PTGS inhibitors TAS Homo sapiens 7401 R-HSA-9716838 https://reactome.org/PathwayBrowser/#/R-HSA-9716838 PTGS1,2 dimers bind PTGS Inhibitors TAS Homo sapiens 7401 R-MMU-9677320 https://reactome.org/PathwayBrowser/#/R-MMU-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Mus musculus 7401 R-MMU-9716836 https://reactome.org/PathwayBrowser/#/R-MMU-9716836 PTGS2 dimer binds PTGS inhibitors IEA Mus musculus 7401 R-MMU-9716838 https://reactome.org/PathwayBrowser/#/R-MMU-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Mus musculus 7401 R-RNO-9677320 https://reactome.org/PathwayBrowser/#/R-RNO-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Rattus norvegicus 7401 R-RNO-9716836 https://reactome.org/PathwayBrowser/#/R-RNO-9716836 PTGS2 dimer binds PTGS inhibitors IEA Rattus norvegicus 7401 R-RNO-9716838 https://reactome.org/PathwayBrowser/#/R-RNO-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Rattus norvegicus 7401 R-SSC-9677320 https://reactome.org/PathwayBrowser/#/R-SSC-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Sus scrofa 7401 R-SSC-9716836 https://reactome.org/PathwayBrowser/#/R-SSC-9716836 PTGS2 dimer binds PTGS inhibitors IEA Sus scrofa 7401 R-SSC-9716838 https://reactome.org/PathwayBrowser/#/R-SSC-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Sus scrofa 7401 R-XTR-9677320 https://reactome.org/PathwayBrowser/#/R-XTR-9677320 PTGS1 dimer binds PTGS1 Inhibitors IEA Xenopus tropicalis 7401 R-XTR-9716836 https://reactome.org/PathwayBrowser/#/R-XTR-9716836 PTGS2 dimer binds PTGS inhibitors IEA Xenopus tropicalis 7401 R-XTR-9716838 https://reactome.org/PathwayBrowser/#/R-XTR-9716838 PTGS1,2 dimers bind PTGS Inhibitors IEA Xenopus tropicalis 7406 R-BTA-9708759 https://reactome.org/PathwayBrowser/#/R-BTA-9708759 DHODH:FMN binds DHODH inhibitors IEA Bos taurus 7406 R-CEL-9708759 https://reactome.org/PathwayBrowser/#/R-CEL-9708759 DHODH:FMN binds DHODH inhibitors IEA Caenorhabditis elegans 7406 R-CFA-9708759 https://reactome.org/PathwayBrowser/#/R-CFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Canis familiaris 7406 R-DME-9708759 https://reactome.org/PathwayBrowser/#/R-DME-9708759 DHODH:FMN binds DHODH inhibitors IEA Drosophila melanogaster 7406 R-DRE-9708759 https://reactome.org/PathwayBrowser/#/R-DRE-9708759 DHODH:FMN binds DHODH inhibitors IEA Danio rerio 7406 R-GGA-9708759 https://reactome.org/PathwayBrowser/#/R-GGA-9708759 DHODH:FMN binds DHODH inhibitors IEA Gallus gallus 7406 R-HSA-9708759 https://reactome.org/PathwayBrowser/#/R-HSA-9708759 DHODH:FMN binds DHODH inhibitors TAS Homo sapiens 7406 R-MMU-9708759 https://reactome.org/PathwayBrowser/#/R-MMU-9708759 DHODH:FMN binds DHODH inhibitors IEA Mus musculus 7406 R-PFA-9708759 https://reactome.org/PathwayBrowser/#/R-PFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Plasmodium falciparum 7406 R-RNO-9708759 https://reactome.org/PathwayBrowser/#/R-RNO-9708759 DHODH:FMN binds DHODH inhibitors IEA Rattus norvegicus 7406 R-SPO-9708759 https://reactome.org/PathwayBrowser/#/R-SPO-9708759 DHODH:FMN binds DHODH inhibitors IEA Schizosaccharomyces pombe 7406 R-SSC-9708759 https://reactome.org/PathwayBrowser/#/R-SSC-9708759 DHODH:FMN binds DHODH inhibitors IEA Sus scrofa 7406 R-XTR-9708759 https://reactome.org/PathwayBrowser/#/R-XTR-9708759 DHODH:FMN binds DHODH inhibitors IEA Xenopus tropicalis 7407 R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 7407 R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 7407 R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 7407 R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 7407 R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 7407 R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 7407 R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 7407 R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 7407 R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 7407 R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 7407 R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 7408 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 7408 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 7408 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 7408 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 7408 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 7408 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 7408 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 7408 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 7408 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 7408 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 7408 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 7408 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 7408 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 7408 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 7408 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 7408 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 7408 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 7408 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 7408 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 7408 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 7408 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 7408 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 7408 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 7408 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 7408 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 7408 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 7408 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 7408 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 7408 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 7408 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 7413 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 7413 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 7413 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 7413 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 7413 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 7413 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 7413 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 7413 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 7413 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 7413 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 7413 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 7413 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 7424 R-HSA-2400010 https://reactome.org/PathwayBrowser/#/R-HSA-2400010 AKT inhibitors block AKT membrane recruitment TAS Homo sapiens 7426 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 7426 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 7426 R-BTA-9669854 https://reactome.org/PathwayBrowser/#/R-BTA-9669854 KIT binds type II TKIs IEA Bos taurus 7426 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 7426 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 7426 R-CEL-9669854 https://reactome.org/PathwayBrowser/#/R-CEL-9669854 KIT binds type II TKIs IEA Caenorhabditis elegans 7426 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 7426 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 7426 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 7426 R-CFA-9669854 https://reactome.org/PathwayBrowser/#/R-CFA-9669854 KIT binds type II TKIs IEA Canis familiaris 7426 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 7426 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 7426 R-DME-9669854 https://reactome.org/PathwayBrowser/#/R-DME-9669854 KIT binds type II TKIs IEA Drosophila melanogaster 7426 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 7426 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 7426 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 7426 R-DRE-9669854 https://reactome.org/PathwayBrowser/#/R-DRE-9669854 KIT binds type II TKIs IEA Danio rerio 7426 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 7426 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 7426 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 7426 R-GGA-9669854 https://reactome.org/PathwayBrowser/#/R-GGA-9669854 KIT binds type II TKIs IEA Gallus gallus 7426 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 7426 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 7426 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 7426 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 7426 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 7426 R-HSA-9669854 https://reactome.org/PathwayBrowser/#/R-HSA-9669854 KIT binds type II TKIs TAS Homo sapiens 7426 R-HSA-9669900 https://reactome.org/PathwayBrowser/#/R-HSA-9669900 KIT mutants bind type II TKIs TAS Homo sapiens 7426 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 7426 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 7426 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 7426 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 7426 R-MMU-9669854 https://reactome.org/PathwayBrowser/#/R-MMU-9669854 KIT binds type II TKIs IEA Mus musculus 7426 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 7426 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 7426 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 7426 R-RNO-9669854 https://reactome.org/PathwayBrowser/#/R-RNO-9669854 KIT binds type II TKIs IEA Rattus norvegicus 7426 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 7426 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 7426 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 7426 R-SSC-9669854 https://reactome.org/PathwayBrowser/#/R-SSC-9669854 KIT binds type II TKIs IEA Sus scrofa 7426 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 7426 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 7426 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 7426 R-XTR-9669854 https://reactome.org/PathwayBrowser/#/R-XTR-9669854 KIT binds type II TKIs IEA Xenopus tropicalis 7426 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 7427 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 7427 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7427 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 7427 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7427 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 7427 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7427 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 7427 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7427 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 7427 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7427 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 7427 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7427 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 7427 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7427 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 7427 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7427 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7427 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 7427 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7427 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7427 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 7427 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7428 R-BTA-9677917 https://reactome.org/PathwayBrowser/#/R-BTA-9677917 MAOA inhibitors bind MAOA:FAD IEA Bos taurus 7428 R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus 7428 R-CFA-9677917 https://reactome.org/PathwayBrowser/#/R-CFA-9677917 MAOA inhibitors bind MAOA:FAD IEA Canis familiaris 7428 R-CFA-9677929 https://reactome.org/PathwayBrowser/#/R-CFA-9677929 MAOB inhibitors bind MAOB:FAD IEA Canis familiaris 7428 R-DDI-9677917 https://reactome.org/PathwayBrowser/#/R-DDI-9677917 MAOA inhibitors bind MAOA:FAD IEA Dictyostelium discoideum 7428 R-DDI-9677929 https://reactome.org/PathwayBrowser/#/R-DDI-9677929 MAOB inhibitors bind MAOB:FAD IEA Dictyostelium discoideum 7428 R-DRE-9677929 https://reactome.org/PathwayBrowser/#/R-DRE-9677929 MAOB inhibitors bind MAOB:FAD IEA Danio rerio 7428 R-GGA-9677917 https://reactome.org/PathwayBrowser/#/R-GGA-9677917 MAOA inhibitors bind MAOA:FAD IEA Gallus gallus 7428 R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus 7428 R-HSA-9677917 https://reactome.org/PathwayBrowser/#/R-HSA-9677917 MAOA inhibitors bind MAOA:FAD TAS Homo sapiens 7428 R-HSA-9677929 https://reactome.org/PathwayBrowser/#/R-HSA-9677929 MAOB inhibitors bind MAOB:FAD TAS Homo sapiens 7428 R-MMU-9677917 https://reactome.org/PathwayBrowser/#/R-MMU-9677917 MAOA inhibitors bind MAOA:FAD IEA Mus musculus 7428 R-MMU-9677929 https://reactome.org/PathwayBrowser/#/R-MMU-9677929 MAOB inhibitors bind MAOB:FAD IEA Mus musculus 7428 R-RNO-9677917 https://reactome.org/PathwayBrowser/#/R-RNO-9677917 MAOA inhibitors bind MAOA:FAD IEA Rattus norvegicus 7428 R-RNO-9677929 https://reactome.org/PathwayBrowser/#/R-RNO-9677929 MAOB inhibitors bind MAOB:FAD IEA Rattus norvegicus 7428 R-SSC-9677917 https://reactome.org/PathwayBrowser/#/R-SSC-9677917 MAOA inhibitors bind MAOA:FAD IEA Sus scrofa 7428 R-SSC-9677929 https://reactome.org/PathwayBrowser/#/R-SSC-9677929 MAOB inhibitors bind MAOB:FAD IEA Sus scrofa 7428 R-XTR-9677929 https://reactome.org/PathwayBrowser/#/R-XTR-9677929 MAOB inhibitors bind MAOB:FAD IEA Xenopus tropicalis 7433 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7434 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 7434 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 7434 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7434 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7434 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 7434 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 7434 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7434 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7434 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 7434 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 7434 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7434 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7434 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7434 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7434 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 7434 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 7434 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7434 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7434 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 7434 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 7434 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7434 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7434 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 7434 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 7434 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7434 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7434 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 7434 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 7434 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7434 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7434 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 7434 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 7434 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7434 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7434 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 7434 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 7434 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 7434 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 7434 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7434 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7434 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7434 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7435 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7435 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7435 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7435 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7435 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7435 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7435 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7435 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7435 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7435 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7435 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7435 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7436 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7436 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7436 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7436 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7436 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7436 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7436 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7436 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7436 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7436 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7436 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7436 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7439 R-BTA-8866329 https://reactome.org/PathwayBrowser/#/R-BTA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Bos taurus 7439 R-BTA-9737780 https://reactome.org/PathwayBrowser/#/R-BTA-9737780 MTTP binds lomitapide IEA Bos taurus 7439 R-CEL-9737780 https://reactome.org/PathwayBrowser/#/R-CEL-9737780 MTTP binds lomitapide IEA Caenorhabditis elegans 7439 R-CFA-8866329 https://reactome.org/PathwayBrowser/#/R-CFA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Canis familiaris 7439 R-CFA-9737780 https://reactome.org/PathwayBrowser/#/R-CFA-9737780 MTTP binds lomitapide IEA Canis familiaris 7439 R-DME-9737780 https://reactome.org/PathwayBrowser/#/R-DME-9737780 MTTP binds lomitapide IEA Drosophila melanogaster 7439 R-DRE-9737780 https://reactome.org/PathwayBrowser/#/R-DRE-9737780 MTTP binds lomitapide IEA Danio rerio 7439 R-GGA-8866329 https://reactome.org/PathwayBrowser/#/R-GGA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Gallus gallus 7439 R-GGA-9737780 https://reactome.org/PathwayBrowser/#/R-GGA-9737780 MTTP binds lomitapide IEA Gallus gallus 7439 R-HSA-8866329 https://reactome.org/PathwayBrowser/#/R-HSA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL TAS Homo sapiens 7439 R-HSA-9737780 https://reactome.org/PathwayBrowser/#/R-HSA-9737780 MTTP binds lomitapide TAS Homo sapiens 7439 R-MMU-8866329 https://reactome.org/PathwayBrowser/#/R-MMU-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Mus musculus 7439 R-MMU-9737780 https://reactome.org/PathwayBrowser/#/R-MMU-9737780 MTTP binds lomitapide IEA Mus musculus 7439 R-RNO-8866329 https://reactome.org/PathwayBrowser/#/R-RNO-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Rattus norvegicus 7439 R-RNO-9737780 https://reactome.org/PathwayBrowser/#/R-RNO-9737780 MTTP binds lomitapide IEA Rattus norvegicus 7439 R-SSC-8866329 https://reactome.org/PathwayBrowser/#/R-SSC-8866329 MTTP lipidates APOB-100, forming a pre-VLDL IEA Sus scrofa 7439 R-SSC-9737780 https://reactome.org/PathwayBrowser/#/R-SSC-9737780 MTTP binds lomitapide IEA Sus scrofa 7439 R-XTR-9737780 https://reactome.org/PathwayBrowser/#/R-XTR-9737780 MTTP binds lomitapide IEA Xenopus tropicalis 7445 R-BTA-9611839 https://reactome.org/PathwayBrowser/#/R-BTA-9611839 β3-agonists bind ADRB3 IEA Bos taurus 7445 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 7445 R-CFA-9611839 https://reactome.org/PathwayBrowser/#/R-CFA-9611839 β3-agonists bind ADRB3 IEA Canis familiaris 7445 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 7445 R-DME-9611839 https://reactome.org/PathwayBrowser/#/R-DME-9611839 β3-agonists bind ADRB3 IEA Drosophila melanogaster 7445 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 7445 R-GGA-9611839 https://reactome.org/PathwayBrowser/#/R-GGA-9611839 β3-agonists bind ADRB3 IEA Gallus gallus 7445 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 7445 R-HSA-9611839 https://reactome.org/PathwayBrowser/#/R-HSA-9611839 β3-agonists bind ADRB3 TAS Homo sapiens 7445 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 7445 R-MMU-9611839 https://reactome.org/PathwayBrowser/#/R-MMU-9611839 β3-agonists bind ADRB3 IEA Mus musculus 7445 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 7445 R-RNO-9611839 https://reactome.org/PathwayBrowser/#/R-RNO-9611839 β3-agonists bind ADRB3 IEA Rattus norvegicus 7445 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 7445 R-SSC-9611839 https://reactome.org/PathwayBrowser/#/R-SSC-9611839 β3-agonists bind ADRB3 IEA Sus scrofa 7445 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 7447 R-BTA-9709454 https://reactome.org/PathwayBrowser/#/R-BTA-9709454 EPOR binds EPOR agonists IEA Bos taurus 7447 R-CFA-9709454 https://reactome.org/PathwayBrowser/#/R-CFA-9709454 EPOR binds EPOR agonists IEA Canis familiaris 7447 R-DME-9709454 https://reactome.org/PathwayBrowser/#/R-DME-9709454 EPOR binds EPOR agonists IEA Drosophila melanogaster 7447 R-HSA-9709454 https://reactome.org/PathwayBrowser/#/R-HSA-9709454 EPOR binds EPOR agonists TAS Homo sapiens 7447 R-MMU-9709454 https://reactome.org/PathwayBrowser/#/R-MMU-9709454 EPOR binds EPOR agonists IEA Mus musculus 7447 R-RNO-9709454 https://reactome.org/PathwayBrowser/#/R-RNO-9709454 EPOR binds EPOR agonists IEA Rattus norvegicus 7447 R-SSC-9709454 https://reactome.org/PathwayBrowser/#/R-SSC-9709454 EPOR binds EPOR agonists IEA Sus scrofa 7447 R-XTR-9709454 https://reactome.org/PathwayBrowser/#/R-XTR-9709454 EPOR binds EPOR agonists IEA Xenopus tropicalis 7448 R-BTA-9708104 https://reactome.org/PathwayBrowser/#/R-BTA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Bos taurus 7448 R-CFA-9708104 https://reactome.org/PathwayBrowser/#/R-CFA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Canis familiaris 7448 R-DME-9708104 https://reactome.org/PathwayBrowser/#/R-DME-9708104 PDE5A dimer binds PDE5A inhibitors IEA Drosophila melanogaster 7448 R-GGA-9708104 https://reactome.org/PathwayBrowser/#/R-GGA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Gallus gallus 7448 R-HSA-9708104 https://reactome.org/PathwayBrowser/#/R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors TAS Homo sapiens 7448 R-MMU-9708104 https://reactome.org/PathwayBrowser/#/R-MMU-9708104 PDE5A dimer binds PDE5A inhibitors IEA Mus musculus 7448 R-RNO-9708104 https://reactome.org/PathwayBrowser/#/R-RNO-9708104 PDE5A dimer binds PDE5A inhibitors IEA Rattus norvegicus 7448 R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa 7448 R-XTR-9708104 https://reactome.org/PathwayBrowser/#/R-XTR-9708104 PDE5A dimer binds PDE5A inhibitors IEA Xenopus tropicalis 7449 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 7449 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 7449 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 7449 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 7449 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 7449 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 7449 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 7449 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 7449 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 7449 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 7449 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 7452 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 7452 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 7452 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 7452 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 7452 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 7452 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 7452 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 7452 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 7452 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 7452 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 7455 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 7455 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 7455 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 7455 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 7455 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 7455 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 7455 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 7455 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 7455 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 7455 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 7455 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 7455 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 7455 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 7455 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 7455 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 7455 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 7455 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 7455 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 7455 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 7455 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 7455 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 7455 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 7455 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 7455 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 7455 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 7455 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 7455 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 7455 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 7455 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 7457 R-BTA-9705794 https://reactome.org/PathwayBrowser/#/R-BTA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Bos taurus 7457 R-CEL-9705794 https://reactome.org/PathwayBrowser/#/R-CEL-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Caenorhabditis elegans 7457 R-CFA-9705794 https://reactome.org/PathwayBrowser/#/R-CFA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Canis familiaris 7457 R-DRE-9705794 https://reactome.org/PathwayBrowser/#/R-DRE-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Danio rerio 7457 R-GGA-9705794 https://reactome.org/PathwayBrowser/#/R-GGA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Gallus gallus 7457 R-HSA-9705794 https://reactome.org/PathwayBrowser/#/R-HSA-9705794 SRD5A2 binds SRD5A2 inhibitors TAS Homo sapiens 7457 R-MMU-9705794 https://reactome.org/PathwayBrowser/#/R-MMU-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Mus musculus 7457 R-RNO-9705794 https://reactome.org/PathwayBrowser/#/R-RNO-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Rattus norvegicus 7457 R-SPO-9705794 https://reactome.org/PathwayBrowser/#/R-SPO-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Schizosaccharomyces pombe 7457 R-SSC-9705794 https://reactome.org/PathwayBrowser/#/R-SSC-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Sus scrofa 7457 R-XTR-9705794 https://reactome.org/PathwayBrowser/#/R-XTR-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Xenopus tropicalis 7459 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 7459 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 7459 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 7459 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 7459 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 7459 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 7459 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 7459 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 7459 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 7459 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 7459 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 7460 R-BTA-9726621 https://reactome.org/PathwayBrowser/#/R-BTA-9726621 PGR binds PGR antagonists IEA Bos taurus 7460 R-CFA-9726621 https://reactome.org/PathwayBrowser/#/R-CFA-9726621 PGR binds PGR antagonists IEA Canis familiaris 7460 R-DME-9726621 https://reactome.org/PathwayBrowser/#/R-DME-9726621 PGR binds PGR antagonists IEA Drosophila melanogaster 7460 R-DRE-9726621 https://reactome.org/PathwayBrowser/#/R-DRE-9726621 PGR binds PGR antagonists IEA Danio rerio 7460 R-GGA-9726621 https://reactome.org/PathwayBrowser/#/R-GGA-9726621 PGR binds PGR antagonists IEA Gallus gallus 7460 R-HSA-9726621 https://reactome.org/PathwayBrowser/#/R-HSA-9726621 PGR binds PGR antagonists TAS Homo sapiens 7460 R-MMU-9726621 https://reactome.org/PathwayBrowser/#/R-MMU-9726621 PGR binds PGR antagonists IEA Mus musculus 7460 R-PFA-9726621 https://reactome.org/PathwayBrowser/#/R-PFA-9726621 PGR binds PGR antagonists IEA Plasmodium falciparum 7460 R-RNO-9726621 https://reactome.org/PathwayBrowser/#/R-RNO-9726621 PGR binds PGR antagonists IEA Rattus norvegicus 7460 R-SSC-9726621 https://reactome.org/PathwayBrowser/#/R-SSC-9726621 PGR binds PGR antagonists IEA Sus scrofa 7462 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 7462 R-BTA-9696179 https://reactome.org/PathwayBrowser/#/R-BTA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Bos taurus 7462 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 7462 R-CFA-9696179 https://reactome.org/PathwayBrowser/#/R-CFA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Canis familiaris 7462 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 7462 R-GGA-9696179 https://reactome.org/PathwayBrowser/#/R-GGA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Gallus gallus 7462 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 7462 R-HSA-9696179 https://reactome.org/PathwayBrowser/#/R-HSA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs TAS Homo sapiens 7462 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 7462 R-MMU-9696179 https://reactome.org/PathwayBrowser/#/R-MMU-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Mus musculus 7462 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 7462 R-RNO-9696179 https://reactome.org/PathwayBrowser/#/R-RNO-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Rattus norvegicus 7462 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 7462 R-SSC-9696179 https://reactome.org/PathwayBrowser/#/R-SSC-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Sus scrofa 7462 R-XTR-9696179 https://reactome.org/PathwayBrowser/#/R-XTR-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Xenopus tropicalis 7465 R-BTA-9613570 https://reactome.org/PathwayBrowser/#/R-BTA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Bos taurus 7465 R-CEL-9613570 https://reactome.org/PathwayBrowser/#/R-CEL-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Caenorhabditis elegans 7465 R-CFA-9613570 https://reactome.org/PathwayBrowser/#/R-CFA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Canis familiaris 7465 R-DME-9613570 https://reactome.org/PathwayBrowser/#/R-DME-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Drosophila melanogaster 7465 R-GGA-9613570 https://reactome.org/PathwayBrowser/#/R-GGA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Gallus gallus 7465 R-HSA-9613570 https://reactome.org/PathwayBrowser/#/R-HSA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers TAS Homo sapiens 7465 R-MMU-9613570 https://reactome.org/PathwayBrowser/#/R-MMU-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Mus musculus 7465 R-PFA-9613570 https://reactome.org/PathwayBrowser/#/R-PFA-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Plasmodium falciparum 7465 R-RNO-9613570 https://reactome.org/PathwayBrowser/#/R-RNO-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Rattus norvegicus 7465 R-SSC-9613570 https://reactome.org/PathwayBrowser/#/R-SSC-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Sus scrofa 7465 R-XTR-9613570 https://reactome.org/PathwayBrowser/#/R-XTR-9613570 Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers IEA Xenopus tropicalis 7468 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 7468 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 7468 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 7468 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 7468 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 7468 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 7468 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 7468 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 7468 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 7468 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 7469 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7469 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7469 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7469 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7469 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7469 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7469 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7469 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7469 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7469 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7469 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7469 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7469 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7469 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7469 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7469 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7469 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7469 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7469 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7469 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7469 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7469 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7474 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 7474 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 7474 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 7474 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 7474 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 7474 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 7474 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 7474 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 7474 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 7474 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 7474 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 7474 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 7474 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 7474 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 7474 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 7474 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 7474 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 7474 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 7474 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 7474 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 7474 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 7474 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 7476 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 7476 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 7476 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 7476 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 7476 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 7476 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 7476 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 7476 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 7476 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 7476 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 7476 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 7476 R-HSA-9715355 https://reactome.org/PathwayBrowser/#/R-HSA-9715355 lorlatinib-resistant ALK mutants don't bind lorlatinib TAS Homo sapiens 7476 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 7476 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 7476 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 7476 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 7476 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 7476 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 7479 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 7479 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 7479 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 7479 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 7479 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 7479 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 7479 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 7479 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 7479 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 7479 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 7479 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 7479 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 7479 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 7479 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 7479 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 7479 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 7479 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 7479 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 7479 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 7479 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 7479 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 7479 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 7479 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 7479 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 7479 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 7479 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 7479 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 7479 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 7479 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 7481 R-HSA-9700266 https://reactome.org/PathwayBrowser/#/R-HSA-9700266 CFTR F508del binds CFTR correctors TAS Homo sapiens 7482 R-BTA-9733292 https://reactome.org/PathwayBrowser/#/R-BTA-9733292 AMY1-3 bind pramlintide IEA Bos taurus 7482 R-CFA-9733292 https://reactome.org/PathwayBrowser/#/R-CFA-9733292 AMY1-3 bind pramlintide IEA Canis familiaris 7482 R-GGA-9733292 https://reactome.org/PathwayBrowser/#/R-GGA-9733292 AMY1-3 bind pramlintide IEA Gallus gallus 7482 R-HSA-9733292 https://reactome.org/PathwayBrowser/#/R-HSA-9733292 AMY1-3 bind pramlintide TAS Homo sapiens 7482 R-MMU-9733292 https://reactome.org/PathwayBrowser/#/R-MMU-9733292 AMY1-3 bind pramlintide IEA Mus musculus 7482 R-RNO-9733292 https://reactome.org/PathwayBrowser/#/R-RNO-9733292 AMY1-3 bind pramlintide IEA Rattus norvegicus 7482 R-SSC-9733292 https://reactome.org/PathwayBrowser/#/R-SSC-9733292 AMY1-3 bind pramlintide IEA Sus scrofa 7482 R-XTR-9733292 https://reactome.org/PathwayBrowser/#/R-XTR-9733292 AMY1-3 bind pramlintide IEA Xenopus tropicalis 7483 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 7483 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 7483 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 7483 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 7483 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 7483 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 7483 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 7483 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 7483 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 7483 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 7483 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 7484 R-BTA-9705794 https://reactome.org/PathwayBrowser/#/R-BTA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Bos taurus 7484 R-CEL-9705794 https://reactome.org/PathwayBrowser/#/R-CEL-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Caenorhabditis elegans 7484 R-CFA-9705794 https://reactome.org/PathwayBrowser/#/R-CFA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Canis familiaris 7484 R-DRE-9705794 https://reactome.org/PathwayBrowser/#/R-DRE-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Danio rerio 7484 R-GGA-9705794 https://reactome.org/PathwayBrowser/#/R-GGA-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Gallus gallus 7484 R-HSA-9705794 https://reactome.org/PathwayBrowser/#/R-HSA-9705794 SRD5A2 binds SRD5A2 inhibitors TAS Homo sapiens 7484 R-MMU-9705794 https://reactome.org/PathwayBrowser/#/R-MMU-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Mus musculus 7484 R-RNO-9705794 https://reactome.org/PathwayBrowser/#/R-RNO-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Rattus norvegicus 7484 R-SPO-9705794 https://reactome.org/PathwayBrowser/#/R-SPO-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Schizosaccharomyces pombe 7484 R-SSC-9705794 https://reactome.org/PathwayBrowser/#/R-SSC-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Sus scrofa 7484 R-XTR-9705794 https://reactome.org/PathwayBrowser/#/R-XTR-9705794 SRD5A2 binds SRD5A2 inhibitors IEA Xenopus tropicalis 7486 R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 7486 R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 7486 R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 7486 R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 7486 R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 7486 R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 7486 R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 7489 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus 7489 R-BTA-9679787 https://reactome.org/PathwayBrowser/#/R-BTA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Bos taurus 7489 R-CFA-3769447 https://reactome.org/PathwayBrowser/#/R-CFA-3769447 HDAC1:2-containing complex deacetylate histones IEA Canis familiaris 7489 R-CFA-9679787 https://reactome.org/PathwayBrowser/#/R-CFA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Canis familiaris 7489 R-DDI-3769447 https://reactome.org/PathwayBrowser/#/R-DDI-3769447 HDAC1:2-containing complex deacetylate histones IEA Dictyostelium discoideum 7489 R-DDI-9679787 https://reactome.org/PathwayBrowser/#/R-DDI-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Dictyostelium discoideum 7489 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster 7489 R-DME-9679787 https://reactome.org/PathwayBrowser/#/R-DME-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Drosophila melanogaster 7489 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus 7489 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus 7489 R-HSA-3769447 https://reactome.org/PathwayBrowser/#/R-HSA-3769447 HDAC1:2-containing complex deacetylate histones TAS Homo sapiens 7489 R-HSA-9679787 https://reactome.org/PathwayBrowser/#/R-HSA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors TAS Homo sapiens 7489 R-MMU-3769447 https://reactome.org/PathwayBrowser/#/R-MMU-3769447 HDAC1:2-containing complex deacetylate histones IEA Mus musculus 7489 R-MMU-9679787 https://reactome.org/PathwayBrowser/#/R-MMU-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Mus musculus 7489 R-RNO-9679787 https://reactome.org/PathwayBrowser/#/R-RNO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Rattus norvegicus 7489 R-SCE-3769447 https://reactome.org/PathwayBrowser/#/R-SCE-3769447 HDAC1:2-containing complex deacetylate histones IEA Saccharomyces cerevisiae 7489 R-SCE-9679787 https://reactome.org/PathwayBrowser/#/R-SCE-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Saccharomyces cerevisiae 7489 R-SPO-3769447 https://reactome.org/PathwayBrowser/#/R-SPO-3769447 HDAC1:2-containing complex deacetylate histones IEA Schizosaccharomyces pombe 7489 R-SPO-9679787 https://reactome.org/PathwayBrowser/#/R-SPO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Schizosaccharomyces pombe 7489 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa 7489 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa 7489 R-XTR-9679787 https://reactome.org/PathwayBrowser/#/R-XTR-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Xenopus tropicalis 7496 R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus 7496 R-BTA-9679787 https://reactome.org/PathwayBrowser/#/R-BTA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Bos taurus 7496 R-CFA-3769447 https://reactome.org/PathwayBrowser/#/R-CFA-3769447 HDAC1:2-containing complex deacetylate histones IEA Canis familiaris 7496 R-CFA-9679787 https://reactome.org/PathwayBrowser/#/R-CFA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Canis familiaris 7496 R-DDI-3769447 https://reactome.org/PathwayBrowser/#/R-DDI-3769447 HDAC1:2-containing complex deacetylate histones IEA Dictyostelium discoideum 7496 R-DDI-9679787 https://reactome.org/PathwayBrowser/#/R-DDI-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Dictyostelium discoideum 7496 R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster 7496 R-DME-9679787 https://reactome.org/PathwayBrowser/#/R-DME-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Drosophila melanogaster 7496 R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus 7496 R-GGA-9679787 https://reactome.org/PathwayBrowser/#/R-GGA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Gallus gallus 7496 R-HSA-3769447 https://reactome.org/PathwayBrowser/#/R-HSA-3769447 HDAC1:2-containing complex deacetylate histones TAS Homo sapiens 7496 R-HSA-9679787 https://reactome.org/PathwayBrowser/#/R-HSA-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors TAS Homo sapiens 7496 R-MMU-3769447 https://reactome.org/PathwayBrowser/#/R-MMU-3769447 HDAC1:2-containing complex deacetylate histones IEA Mus musculus 7496 R-MMU-9679787 https://reactome.org/PathwayBrowser/#/R-MMU-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Mus musculus 7496 R-RNO-9679787 https://reactome.org/PathwayBrowser/#/R-RNO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Rattus norvegicus 7496 R-SCE-3769447 https://reactome.org/PathwayBrowser/#/R-SCE-3769447 HDAC1:2-containing complex deacetylate histones IEA Saccharomyces cerevisiae 7496 R-SCE-9679787 https://reactome.org/PathwayBrowser/#/R-SCE-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Saccharomyces cerevisiae 7496 R-SPO-3769447 https://reactome.org/PathwayBrowser/#/R-SPO-3769447 HDAC1:2-containing complex deacetylate histones IEA Schizosaccharomyces pombe 7496 R-SPO-9679787 https://reactome.org/PathwayBrowser/#/R-SPO-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Schizosaccharomyces pombe 7496 R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa 7496 R-SSC-9679787 https://reactome.org/PathwayBrowser/#/R-SSC-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Sus scrofa 7496 R-XTR-9679787 https://reactome.org/PathwayBrowser/#/R-XTR-9679787 HDAC1:2-containing complex binds HDAC2 Inhibitors IEA Xenopus tropicalis 7532 R-HSA-5210912 https://reactome.org/PathwayBrowser/#/R-HSA-5210912 Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) TAS Homo sapiens 7532 R-HSA-5210935 https://reactome.org/PathwayBrowser/#/R-HSA-5210935 Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) TAS Homo sapiens 7532 R-HSA-9683546 https://reactome.org/PathwayBrowser/#/R-HSA-9683546 FURIN binds furin inhibitors TAS Homo sapiens 7535 R-BTA-9678766 https://reactome.org/PathwayBrowser/#/R-BTA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Bos taurus 7535 R-CFA-9678766 https://reactome.org/PathwayBrowser/#/R-CFA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Canis familiaris 7535 R-DRE-9678766 https://reactome.org/PathwayBrowser/#/R-DRE-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Danio rerio 7535 R-GGA-9678766 https://reactome.org/PathwayBrowser/#/R-GGA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Gallus gallus 7535 R-HSA-9678766 https://reactome.org/PathwayBrowser/#/R-HSA-9678766 CYP3A4 binds CYP3A4 inhibitors TAS Homo sapiens 7535 R-MMU-9678766 https://reactome.org/PathwayBrowser/#/R-MMU-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Mus musculus 7535 R-RNO-9678766 https://reactome.org/PathwayBrowser/#/R-RNO-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Rattus norvegicus 7535 R-SSC-9678766 https://reactome.org/PathwayBrowser/#/R-SSC-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Sus scrofa 7535 R-XTR-9678766 https://reactome.org/PathwayBrowser/#/R-XTR-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Xenopus tropicalis 7547 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7547 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7547 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7547 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7547 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7547 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7547 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7547 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7547 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7547 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7547 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7547 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7549 R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 7549 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7549 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 7549 R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 7549 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7549 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 7549 R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 7549 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7549 R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 7549 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7549 R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 7549 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7549 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 7549 R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 7549 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7549 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 7549 R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 7549 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7549 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 7549 R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 7549 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7549 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7549 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 7549 R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 7549 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7549 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 7549 R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 7549 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7549 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 7549 R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 7549 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7551 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7551 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7551 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7551 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7551 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7551 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7551 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7551 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7551 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7551 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7551 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7551 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7554 R-BTA-9714580 https://reactome.org/PathwayBrowser/#/R-BTA-9714580 SLC6A3 binds DRIs IEA Bos taurus 7554 R-CEL-9714580 https://reactome.org/PathwayBrowser/#/R-CEL-9714580 SLC6A3 binds DRIs IEA Caenorhabditis elegans 7554 R-CFA-9714580 https://reactome.org/PathwayBrowser/#/R-CFA-9714580 SLC6A3 binds DRIs IEA Canis familiaris 7554 R-DME-9714580 https://reactome.org/PathwayBrowser/#/R-DME-9714580 SLC6A3 binds DRIs IEA Drosophila melanogaster 7554 R-DRE-9714580 https://reactome.org/PathwayBrowser/#/R-DRE-9714580 SLC6A3 binds DRIs IEA Danio rerio 7554 R-HSA-9714580 https://reactome.org/PathwayBrowser/#/R-HSA-9714580 SLC6A3 binds DRIs TAS Homo sapiens 7554 R-MMU-9714580 https://reactome.org/PathwayBrowser/#/R-MMU-9714580 SLC6A3 binds DRIs IEA Mus musculus 7554 R-PFA-9714580 https://reactome.org/PathwayBrowser/#/R-PFA-9714580 SLC6A3 binds DRIs IEA Plasmodium falciparum 7554 R-RNO-9714580 https://reactome.org/PathwayBrowser/#/R-RNO-9714580 SLC6A3 binds DRIs IEA Rattus norvegicus 7554 R-SSC-9714580 https://reactome.org/PathwayBrowser/#/R-SSC-9714580 SLC6A3 binds DRIs IEA Sus scrofa 7554 R-XTR-9714580 https://reactome.org/PathwayBrowser/#/R-XTR-9714580 SLC6A3 binds DRIs IEA Xenopus tropicalis 7555 R-BTA-9714580 https://reactome.org/PathwayBrowser/#/R-BTA-9714580 SLC6A3 binds DRIs IEA Bos taurus 7555 R-CEL-9714580 https://reactome.org/PathwayBrowser/#/R-CEL-9714580 SLC6A3 binds DRIs IEA Caenorhabditis elegans 7555 R-CFA-9714580 https://reactome.org/PathwayBrowser/#/R-CFA-9714580 SLC6A3 binds DRIs IEA Canis familiaris 7555 R-DME-9714580 https://reactome.org/PathwayBrowser/#/R-DME-9714580 SLC6A3 binds DRIs IEA Drosophila melanogaster 7555 R-DRE-9714580 https://reactome.org/PathwayBrowser/#/R-DRE-9714580 SLC6A3 binds DRIs IEA Danio rerio 7555 R-HSA-9714580 https://reactome.org/PathwayBrowser/#/R-HSA-9714580 SLC6A3 binds DRIs TAS Homo sapiens 7555 R-MMU-9714580 https://reactome.org/PathwayBrowser/#/R-MMU-9714580 SLC6A3 binds DRIs IEA Mus musculus 7555 R-PFA-9714580 https://reactome.org/PathwayBrowser/#/R-PFA-9714580 SLC6A3 binds DRIs IEA Plasmodium falciparum 7555 R-RNO-9714580 https://reactome.org/PathwayBrowser/#/R-RNO-9714580 SLC6A3 binds DRIs IEA Rattus norvegicus 7555 R-SSC-9714580 https://reactome.org/PathwayBrowser/#/R-SSC-9714580 SLC6A3 binds DRIs IEA Sus scrofa 7555 R-XTR-9714580 https://reactome.org/PathwayBrowser/#/R-XTR-9714580 SLC6A3 binds DRIs IEA Xenopus tropicalis 7556 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 7556 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 7556 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 7556 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 7556 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 7556 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 7556 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 7556 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 7556 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 7556 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 7557 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 7557 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 7557 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 7557 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 7557 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 7557 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 7557 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 7557 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 7557 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 7557 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 7575 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 7575 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 7575 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 7575 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 7575 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 7575 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 7575 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 7575 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 7575 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 7575 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 7575 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 7575 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 7575 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 7575 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 7575 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 7575 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 7575 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 7575 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 7575 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 7575 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 7575 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 7575 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 7575 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 7575 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 7575 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 7575 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 7575 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 7575 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 7575 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 7575 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 7597 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 7597 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 7597 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 7597 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 7597 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 7597 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 7597 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 7597 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 7597 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 7597 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 7597 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 7597 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 7597 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 7597 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 7597 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 7598 R-BTA-9009817 https://reactome.org/PathwayBrowser/#/R-BTA-9009817 Acitretin binds to RAR:RXR IEA Bos taurus 7598 R-CEL-9009817 https://reactome.org/PathwayBrowser/#/R-CEL-9009817 Acitretin binds to RAR:RXR IEA Caenorhabditis elegans 7598 R-CFA-9009817 https://reactome.org/PathwayBrowser/#/R-CFA-9009817 Acitretin binds to RAR:RXR IEA Canis familiaris 7598 R-DME-9009817 https://reactome.org/PathwayBrowser/#/R-DME-9009817 Acitretin binds to RAR:RXR IEA Drosophila melanogaster 7598 R-DRE-9009817 https://reactome.org/PathwayBrowser/#/R-DRE-9009817 Acitretin binds to RAR:RXR IEA Danio rerio 7598 R-GGA-9009817 https://reactome.org/PathwayBrowser/#/R-GGA-9009817 Acitretin binds to RAR:RXR IEA Gallus gallus 7598 R-HSA-9009817 https://reactome.org/PathwayBrowser/#/R-HSA-9009817 Acitretin binds to RAR:RXR TAS Homo sapiens 7598 R-MMU-9009817 https://reactome.org/PathwayBrowser/#/R-MMU-9009817 Acitretin binds to RAR:RXR IEA Mus musculus 7598 R-RNO-9009817 https://reactome.org/PathwayBrowser/#/R-RNO-9009817 Acitretin binds to RAR:RXR IEA Rattus norvegicus 7598 R-SSC-9009817 https://reactome.org/PathwayBrowser/#/R-SSC-9009817 Acitretin binds to RAR:RXR IEA Sus scrofa 7610 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 7610 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 7610 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 7610 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 7610 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 7610 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 7610 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 7610 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 7610 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 7610 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 7613 R-BTA-9709109 https://reactome.org/PathwayBrowser/#/R-BTA-9709109 DHFR dimer binds DHFR inhibitors IEA Bos taurus 7613 R-CEL-9709109 https://reactome.org/PathwayBrowser/#/R-CEL-9709109 DHFR dimer binds DHFR inhibitors IEA Caenorhabditis elegans 7613 R-CFA-9709109 https://reactome.org/PathwayBrowser/#/R-CFA-9709109 DHFR dimer binds DHFR inhibitors IEA Canis familiaris 7613 R-DDI-9709109 https://reactome.org/PathwayBrowser/#/R-DDI-9709109 DHFR dimer binds DHFR inhibitors IEA Dictyostelium discoideum 7613 R-DME-9709109 https://reactome.org/PathwayBrowser/#/R-DME-9709109 DHFR dimer binds DHFR inhibitors IEA Drosophila melanogaster 7613 R-DRE-9709109 https://reactome.org/PathwayBrowser/#/R-DRE-9709109 DHFR dimer binds DHFR inhibitors IEA Danio rerio 7613 R-GGA-9709109 https://reactome.org/PathwayBrowser/#/R-GGA-9709109 DHFR dimer binds DHFR inhibitors IEA Gallus gallus 7613 R-HSA-9709109 https://reactome.org/PathwayBrowser/#/R-HSA-9709109 DHFR dimer binds DHFR inhibitors TAS Homo sapiens 7613 R-MMU-9709109 https://reactome.org/PathwayBrowser/#/R-MMU-9709109 DHFR dimer binds DHFR inhibitors IEA Mus musculus 7613 R-RNO-9709109 https://reactome.org/PathwayBrowser/#/R-RNO-9709109 DHFR dimer binds DHFR inhibitors IEA Rattus norvegicus 7613 R-SCE-9709109 https://reactome.org/PathwayBrowser/#/R-SCE-9709109 DHFR dimer binds DHFR inhibitors IEA Saccharomyces cerevisiae 7613 R-SPO-9709109 https://reactome.org/PathwayBrowser/#/R-SPO-9709109 DHFR dimer binds DHFR inhibitors IEA Schizosaccharomyces pombe 7613 R-SSC-9709109 https://reactome.org/PathwayBrowser/#/R-SSC-9709109 DHFR dimer binds DHFR inhibitors IEA Sus scrofa 7620 R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 7620 R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 7620 R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 7620 R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 7620 R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 7620 R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 7620 R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 7620 R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 7620 R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 7620 R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 7620 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7620 R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 7620 R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 7620 R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 7620 R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 7620 R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 7620 R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 7620 R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 7620 R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 7620 R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 7620 R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 7621 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7621 R-MMU-9750281 https://reactome.org/PathwayBrowser/#/R-MMU-9750281 Uramustine produces interstrand crosslinks in mouse DNA TAS Mus musculus 7622 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7622 R-MMU-9750097 https://reactome.org/PathwayBrowser/#/R-MMU-9750097 ThioTEPA produces interstrand crosslinks in mouse DNA TAS Mus musculus 7624 R-HSA-9713785 https://reactome.org/PathwayBrowser/#/R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks IEA Homo sapiens 7626 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 7626 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 7626 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 7626 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 7626 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 7626 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 7626 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 7626 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 7626 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 7626 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 7626 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 7626 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 7626 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 7626 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 7626 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 7626 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 7626 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 7626 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 7637 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 7637 R-BTA-9696179 https://reactome.org/PathwayBrowser/#/R-BTA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Bos taurus 7637 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 7637 R-CFA-9696179 https://reactome.org/PathwayBrowser/#/R-CFA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Canis familiaris 7637 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 7637 R-GGA-9696179 https://reactome.org/PathwayBrowser/#/R-GGA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Gallus gallus 7637 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 7637 R-HSA-9696179 https://reactome.org/PathwayBrowser/#/R-HSA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs TAS Homo sapiens 7637 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 7637 R-MMU-9696179 https://reactome.org/PathwayBrowser/#/R-MMU-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Mus musculus 7637 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 7637 R-RNO-9696179 https://reactome.org/PathwayBrowser/#/R-RNO-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Rattus norvegicus 7637 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 7637 R-SSC-9696179 https://reactome.org/PathwayBrowser/#/R-SSC-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Sus scrofa 7637 R-XTR-9696179 https://reactome.org/PathwayBrowser/#/R-XTR-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Xenopus tropicalis 7638 R-BTA-9728664 https://reactome.org/PathwayBrowser/#/R-BTA-9728664 GLP1R binds GLP1R agonists IEA Bos taurus 7638 R-CFA-9728664 https://reactome.org/PathwayBrowser/#/R-CFA-9728664 GLP1R binds GLP1R agonists IEA Canis familiaris 7638 R-DRE-9728664 https://reactome.org/PathwayBrowser/#/R-DRE-9728664 GLP1R binds GLP1R agonists IEA Danio rerio 7638 R-HSA-9728664 https://reactome.org/PathwayBrowser/#/R-HSA-9728664 GLP1R binds GLP1R agonists TAS Homo sapiens 7638 R-MMU-9728664 https://reactome.org/PathwayBrowser/#/R-MMU-9728664 GLP1R binds GLP1R agonists IEA Mus musculus 7638 R-RNO-9728664 https://reactome.org/PathwayBrowser/#/R-RNO-9728664 GLP1R binds GLP1R agonists IEA Rattus norvegicus 7638 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa 7643 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 7643 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 7643 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 7643 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 7643 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 7643 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 7643 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 7643 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 7643 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 7643 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 7643 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 7643 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 7643 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 7643 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 7643 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 7643 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 7643 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 7643 R-HSA-9665278 https://reactome.org/PathwayBrowser/#/R-HSA-9665278 Resistant ERBB2 KD mutants do not bind AEE788 TAS Homo sapiens 7643 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 7643 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 7643 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 7643 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 7643 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 7643 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 7644 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 7644 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 7649 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 7649 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 7649 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 7670 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 7670 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 7670 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 7670 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 7670 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 7670 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 7670 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 7670 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 7670 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 7670 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 7671 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 7671 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 7671 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 7671 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 7671 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 7671 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 7671 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 7671 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 7671 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 7671 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 7706 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 7706 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 7706 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 7706 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 7706 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 7706 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 7706 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 7706 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 7706 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 7706 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 7706 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 7706 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 7706 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 7706 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 7706 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 7706 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 7706 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 7707 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 7707 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 7707 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 7707 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 7717 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 7717 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 7717 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 7717 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 7717 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 7717 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 7717 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 7717 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 7717 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 7717 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 7717 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 7717 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 7717 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 7717 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 7717 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 7717 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 7717 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 7717 R-HSA-9665304 https://reactome.org/PathwayBrowser/#/R-HSA-9665304 ERBB2 T862A does not bind sapitinib TAS Homo sapiens 7717 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 7717 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 7717 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 7717 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 7717 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 7717 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 7719 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 7719 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 7719 R-HSA-9665280 https://reactome.org/PathwayBrowser/#/R-HSA-9665280 ERBB2 KD mutants do not bind osimertinib TAS Homo sapiens 7739 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 7739 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 7739 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 7739 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 7739 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 7739 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 7739 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 7739 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 7739 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 7739 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 7739 R-HSA-9700656 https://reactome.org/PathwayBrowser/#/R-HSA-9700656 alectinib resistant ALK mutants don't bind alectinib TAS Homo sapiens 7739 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 7739 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 7739 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 7739 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 7739 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 7739 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 7739 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 7740 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 7740 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 7740 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 7740 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 7740 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 7740 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 7740 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 7740 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 7740 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 7740 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 7740 R-HSA-9700646 https://reactome.org/PathwayBrowser/#/R-HSA-9700646 ASP-3026- resistant ALK mutants don't bind ASP-3026 TAS Homo sapiens 7740 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 7740 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 7740 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 7740 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 7740 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 7740 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 7740 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 7741 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 7741 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 7741 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 7741 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 7741 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 7741 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 7741 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 7741 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 7741 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 7741 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 7741 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 7741 R-HSA-9715356 https://reactome.org/PathwayBrowser/#/R-HSA-9715356 brigatinib-resistant ALK mutants don't bind brigatinib TAS Homo sapiens 7741 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 7741 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 7741 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 7741 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 7741 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 7741 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 7744 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 7744 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 7744 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 7744 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 7744 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 7744 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 7744 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 7744 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 7744 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 7744 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 7744 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 7744 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 7744 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 7744 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 7744 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 7744 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 7744 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 7744 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 7748 R-BTA-6800298 https://reactome.org/PathwayBrowser/#/R-BTA-6800298 HGF dimer binds MET IEA Bos taurus 7748 R-BTA-9734070 https://reactome.org/PathwayBrowser/#/R-BTA-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Bos taurus 7748 R-CEL-6800298 https://reactome.org/PathwayBrowser/#/R-CEL-6800298 HGF dimer binds MET IEA Caenorhabditis elegans 7748 R-CEL-9734070 https://reactome.org/PathwayBrowser/#/R-CEL-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Caenorhabditis elegans 7748 R-CFA-6800298 https://reactome.org/PathwayBrowser/#/R-CFA-6800298 HGF dimer binds MET IEA Canis familiaris 7748 R-CFA-9734070 https://reactome.org/PathwayBrowser/#/R-CFA-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Canis familiaris 7748 R-DRE-9734070 https://reactome.org/PathwayBrowser/#/R-DRE-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Danio rerio 7748 R-GGA-6800298 https://reactome.org/PathwayBrowser/#/R-GGA-6800298 HGF dimer binds MET IEA Gallus gallus 7748 R-GGA-9734070 https://reactome.org/PathwayBrowser/#/R-GGA-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Gallus gallus 7748 R-HSA-6800298 https://reactome.org/PathwayBrowser/#/R-HSA-6800298 HGF dimer binds MET TAS Homo sapiens 7748 R-HSA-9734070 https://reactome.org/PathwayBrowser/#/R-HSA-9734070 Anti-MET recombinant therapeutic antibodies bind MET TAS Homo sapiens 7748 R-MMU-6800298 https://reactome.org/PathwayBrowser/#/R-MMU-6800298 HGF dimer binds MET IEA Mus musculus 7748 R-MMU-9734070 https://reactome.org/PathwayBrowser/#/R-MMU-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Mus musculus 7748 R-RNO-6800298 https://reactome.org/PathwayBrowser/#/R-RNO-6800298 HGF dimer binds MET IEA Rattus norvegicus 7748 R-RNO-9734070 https://reactome.org/PathwayBrowser/#/R-RNO-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Rattus norvegicus 7748 R-SSC-6800298 https://reactome.org/PathwayBrowser/#/R-SSC-6800298 HGF dimer binds MET IEA Sus scrofa 7748 R-SSC-9734070 https://reactome.org/PathwayBrowser/#/R-SSC-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Sus scrofa 7748 R-XTR-6800298 https://reactome.org/PathwayBrowser/#/R-XTR-6800298 HGF dimer binds MET IEA Xenopus tropicalis 7748 R-XTR-9734070 https://reactome.org/PathwayBrowser/#/R-XTR-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Xenopus tropicalis 7751 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 7767 R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 7767 R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 7767 R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 7767 R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 7767 R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 7767 R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 7767 R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 7767 R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 7767 R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 7767 R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 7792 R-BTA-451895 https://reactome.org/PathwayBrowser/#/R-BTA-451895 IL2RG binds JAK3 IEA Bos taurus 7792 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 7792 R-BTA-909724 https://reactome.org/PathwayBrowser/#/R-BTA-909724 Recruitment of IFNAR1 IEA Bos taurus 7792 R-BTA-9678561 https://reactome.org/PathwayBrowser/#/R-BTA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Bos taurus 7792 R-BTA-9678737 https://reactome.org/PathwayBrowser/#/R-BTA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Bos taurus 7792 R-BTA-9678935 https://reactome.org/PathwayBrowser/#/R-BTA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Bos taurus 7792 R-BTA-9679028 https://reactome.org/PathwayBrowser/#/R-BTA-9679028 JAK3 binds JAK3 inhibitors IEA Bos taurus 7792 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 7792 R-CFA-909724 https://reactome.org/PathwayBrowser/#/R-CFA-909724 Recruitment of IFNAR1 IEA Canis familiaris 7792 R-CFA-9678561 https://reactome.org/PathwayBrowser/#/R-CFA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Canis familiaris 7792 R-CFA-9678737 https://reactome.org/PathwayBrowser/#/R-CFA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Canis familiaris 7792 R-CFA-9678935 https://reactome.org/PathwayBrowser/#/R-CFA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Canis familiaris 7792 R-CFA-9679028 https://reactome.org/PathwayBrowser/#/R-CFA-9679028 JAK3 binds JAK3 inhibitors IEA Canis familiaris 7792 R-DME-9679028 https://reactome.org/PathwayBrowser/#/R-DME-9679028 JAK3 binds JAK3 inhibitors IEA Drosophila melanogaster 7792 R-DRE-9678561 https://reactome.org/PathwayBrowser/#/R-DRE-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Danio rerio 7792 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 7792 R-GGA-909724 https://reactome.org/PathwayBrowser/#/R-GGA-909724 Recruitment of IFNAR1 IEA Gallus gallus 7792 R-GGA-9678561 https://reactome.org/PathwayBrowser/#/R-GGA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Gallus gallus 7792 R-GGA-9678737 https://reactome.org/PathwayBrowser/#/R-GGA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Gallus gallus 7792 R-GGA-9678935 https://reactome.org/PathwayBrowser/#/R-GGA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Gallus gallus 7792 R-HSA-451895 https://reactome.org/PathwayBrowser/#/R-HSA-451895 IL2RG binds JAK3 TAS Homo sapiens 7792 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 7792 R-HSA-909724 https://reactome.org/PathwayBrowser/#/R-HSA-909724 Recruitment of IFNAR1 TAS Homo sapiens 7792 R-HSA-9678561 https://reactome.org/PathwayBrowser/#/R-HSA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors TAS Homo sapiens 7792 R-HSA-9678737 https://reactome.org/PathwayBrowser/#/R-HSA-9678737 IFNAR1:TYK2 binds TYK2 inhibitors TAS Homo sapiens 7792 R-HSA-9678935 https://reactome.org/PathwayBrowser/#/R-HSA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors TAS Homo sapiens 7792 R-HSA-9679028 https://reactome.org/PathwayBrowser/#/R-HSA-9679028 JAK3 binds JAK3 inhibitors TAS Homo sapiens 7792 R-MMU-451895 https://reactome.org/PathwayBrowser/#/R-MMU-451895 IL2RG binds JAK3 IEA Mus musculus 7792 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 7792 R-MMU-909724 https://reactome.org/PathwayBrowser/#/R-MMU-909724 Recruitment of IFNAR1 IEA Mus musculus 7792 R-MMU-9678561 https://reactome.org/PathwayBrowser/#/R-MMU-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Mus musculus 7792 R-MMU-9678737 https://reactome.org/PathwayBrowser/#/R-MMU-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Mus musculus 7792 R-MMU-9678935 https://reactome.org/PathwayBrowser/#/R-MMU-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Mus musculus 7792 R-MMU-9679028 https://reactome.org/PathwayBrowser/#/R-MMU-9679028 JAK3 binds JAK3 inhibitors IEA Mus musculus 7792 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 7792 R-RNO-909724 https://reactome.org/PathwayBrowser/#/R-RNO-909724 Recruitment of IFNAR1 IEA Rattus norvegicus 7792 R-RNO-9678561 https://reactome.org/PathwayBrowser/#/R-RNO-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Rattus norvegicus 7792 R-RNO-9678737 https://reactome.org/PathwayBrowser/#/R-RNO-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Rattus norvegicus 7792 R-RNO-9678935 https://reactome.org/PathwayBrowser/#/R-RNO-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Rattus norvegicus 7792 R-RNO-9679028 https://reactome.org/PathwayBrowser/#/R-RNO-9679028 JAK3 binds JAK3 inhibitors IEA Rattus norvegicus 7792 R-SSC-451895 https://reactome.org/PathwayBrowser/#/R-SSC-451895 IL2RG binds JAK3 IEA Sus scrofa 7792 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 7792 R-SSC-909724 https://reactome.org/PathwayBrowser/#/R-SSC-909724 Recruitment of IFNAR1 IEA Sus scrofa 7792 R-SSC-9678561 https://reactome.org/PathwayBrowser/#/R-SSC-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Sus scrofa 7792 R-SSC-9678737 https://reactome.org/PathwayBrowser/#/R-SSC-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Sus scrofa 7792 R-SSC-9678935 https://reactome.org/PathwayBrowser/#/R-SSC-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Sus scrofa 7792 R-SSC-9679028 https://reactome.org/PathwayBrowser/#/R-SSC-9679028 JAK3 binds JAK3 inhibitors IEA Sus scrofa 7792 R-XTR-909724 https://reactome.org/PathwayBrowser/#/R-XTR-909724 Recruitment of IFNAR1 IEA Xenopus tropicalis 7792 R-XTR-9678561 https://reactome.org/PathwayBrowser/#/R-XTR-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 7792 R-XTR-9678737 https://reactome.org/PathwayBrowser/#/R-XTR-9678737 IFNAR1:TYK2 binds TYK2 inhibitors IEA Xenopus tropicalis 7792 R-XTR-9678935 https://reactome.org/PathwayBrowser/#/R-XTR-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 7792 R-XTR-9679028 https://reactome.org/PathwayBrowser/#/R-XTR-9679028 JAK3 binds JAK3 inhibitors IEA Xenopus tropicalis 7819 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 7819 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 7819 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 7837 R-BTA-9691421 https://reactome.org/PathwayBrowser/#/R-BTA-9691421 BTK binds BTK inhibitors IEA Bos taurus 7837 R-CFA-9691421 https://reactome.org/PathwayBrowser/#/R-CFA-9691421 BTK binds BTK inhibitors IEA Canis familiaris 7837 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus 7837 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens 7837 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus 7837 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus 7837 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa 7857 R-BTA-9727567 https://reactome.org/PathwayBrowser/#/R-BTA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Bos taurus 7857 R-CEL-9727567 https://reactome.org/PathwayBrowser/#/R-CEL-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Caenorhabditis elegans 7857 R-CFA-9727567 https://reactome.org/PathwayBrowser/#/R-CFA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Canis familiaris 7857 R-DDI-9727567 https://reactome.org/PathwayBrowser/#/R-DDI-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Dictyostelium discoideum 7857 R-DME-9727567 https://reactome.org/PathwayBrowser/#/R-DME-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Drosophila melanogaster 7857 R-DRE-9727567 https://reactome.org/PathwayBrowser/#/R-DRE-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Danio rerio 7857 R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus 7857 R-HSA-9727567 https://reactome.org/PathwayBrowser/#/R-HSA-9727567 CES1 hydrolyses sacubitril to sacubitrilat TAS Homo sapiens 7857 R-MMU-9727567 https://reactome.org/PathwayBrowser/#/R-MMU-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Mus musculus 7857 R-RNO-9727567 https://reactome.org/PathwayBrowser/#/R-RNO-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Rattus norvegicus 7857 R-SSC-9727567 https://reactome.org/PathwayBrowser/#/R-SSC-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Sus scrofa 7857 R-XTR-9727567 https://reactome.org/PathwayBrowser/#/R-XTR-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Xenopus tropicalis 7858 R-BTA-9727567 https://reactome.org/PathwayBrowser/#/R-BTA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Bos taurus 7858 R-BTA-9727607 https://reactome.org/PathwayBrowser/#/R-BTA-9727607 MME:Zn2+ binds sacubitrilat IEA Bos taurus 7858 R-CEL-9727567 https://reactome.org/PathwayBrowser/#/R-CEL-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Caenorhabditis elegans 7858 R-CEL-9727607 https://reactome.org/PathwayBrowser/#/R-CEL-9727607 MME:Zn2+ binds sacubitrilat IEA Caenorhabditis elegans 7858 R-CFA-9727567 https://reactome.org/PathwayBrowser/#/R-CFA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Canis familiaris 7858 R-CFA-9727607 https://reactome.org/PathwayBrowser/#/R-CFA-9727607 MME:Zn2+ binds sacubitrilat IEA Canis familiaris 7858 R-DDI-9727567 https://reactome.org/PathwayBrowser/#/R-DDI-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Dictyostelium discoideum 7858 R-DME-9727567 https://reactome.org/PathwayBrowser/#/R-DME-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Drosophila melanogaster 7858 R-DME-9727607 https://reactome.org/PathwayBrowser/#/R-DME-9727607 MME:Zn2+ binds sacubitrilat IEA Drosophila melanogaster 7858 R-DRE-9727567 https://reactome.org/PathwayBrowser/#/R-DRE-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Danio rerio 7858 R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus 7858 R-GGA-9727607 https://reactome.org/PathwayBrowser/#/R-GGA-9727607 MME:Zn2+ binds sacubitrilat IEA Gallus gallus 7858 R-HSA-9727567 https://reactome.org/PathwayBrowser/#/R-HSA-9727567 CES1 hydrolyses sacubitril to sacubitrilat TAS Homo sapiens 7858 R-HSA-9727607 https://reactome.org/PathwayBrowser/#/R-HSA-9727607 MME:Zn2+ binds sacubitrilat TAS Homo sapiens 7858 R-MMU-9727567 https://reactome.org/PathwayBrowser/#/R-MMU-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Mus musculus 7858 R-MMU-9727607 https://reactome.org/PathwayBrowser/#/R-MMU-9727607 MME:Zn2+ binds sacubitrilat IEA Mus musculus 7858 R-RNO-9727567 https://reactome.org/PathwayBrowser/#/R-RNO-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Rattus norvegicus 7858 R-RNO-9727607 https://reactome.org/PathwayBrowser/#/R-RNO-9727607 MME:Zn2+ binds sacubitrilat IEA Rattus norvegicus 7858 R-SSC-9727567 https://reactome.org/PathwayBrowser/#/R-SSC-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Sus scrofa 7858 R-SSC-9727607 https://reactome.org/PathwayBrowser/#/R-SSC-9727607 MME:Zn2+ binds sacubitrilat IEA Sus scrofa 7858 R-XTR-9727567 https://reactome.org/PathwayBrowser/#/R-XTR-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Xenopus tropicalis 7858 R-XTR-9727607 https://reactome.org/PathwayBrowser/#/R-XTR-9727607 MME:Zn2+ binds sacubitrilat IEA Xenopus tropicalis 7862 R-HSA-9685655 https://reactome.org/PathwayBrowser/#/R-HSA-9685655 CTSL bind CTSL inhibitors TAS Homo sapiens 7862 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 7862 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 7871 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 7871 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 7871 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 7871 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 7871 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 7871 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 7871 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 7871 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 7872 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 7872 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 7872 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 7872 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 7872 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 7872 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 7872 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 7872 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 7872 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 7872 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 7872 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 7872 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 7872 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 7872 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 7872 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 7872 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 7872 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 7872 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 7876 R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 7876 R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 7876 R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 7876 R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 7876 R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 7876 R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 7876 R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 7876 R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 7877 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 7877 R-HSA-2029992 https://reactome.org/PathwayBrowser/#/R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants TAS Homo sapiens 7877 R-HSA-2077420 https://reactome.org/PathwayBrowser/#/R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 7877 R-HSA-2077424 https://reactome.org/PathwayBrowser/#/R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors TAS Homo sapiens 7878 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 7882 R-BTA-389083 https://reactome.org/PathwayBrowser/#/R-BTA-389083 Autophosphorylation of PDGF alpha receptors IEA Bos taurus 7882 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 7882 R-BTA-9674093 https://reactome.org/PathwayBrowser/#/R-BTA-9674093 PDGFRs bind type I TKI IEA Bos taurus 7882 R-CEL-389083 https://reactome.org/PathwayBrowser/#/R-CEL-389083 Autophosphorylation of PDGF alpha receptors IEA Caenorhabditis elegans 7882 R-CEL-9674093 https://reactome.org/PathwayBrowser/#/R-CEL-9674093 PDGFRs bind type I TKI IEA Caenorhabditis elegans 7882 R-CFA-389083 https://reactome.org/PathwayBrowser/#/R-CFA-389083 Autophosphorylation of PDGF alpha receptors IEA Canis familiaris 7882 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 7882 R-CFA-9674093 https://reactome.org/PathwayBrowser/#/R-CFA-9674093 PDGFRs bind type I TKI IEA Canis familiaris 7882 R-DME-389083 https://reactome.org/PathwayBrowser/#/R-DME-389083 Autophosphorylation of PDGF alpha receptors IEA Drosophila melanogaster 7882 R-DME-9674093 https://reactome.org/PathwayBrowser/#/R-DME-9674093 PDGFRs bind type I TKI IEA Drosophila melanogaster 7882 R-DRE-389083 https://reactome.org/PathwayBrowser/#/R-DRE-389083 Autophosphorylation of PDGF alpha receptors IEA Danio rerio 7882 R-DRE-9674093 https://reactome.org/PathwayBrowser/#/R-DRE-9674093 PDGFRs bind type I TKI IEA Danio rerio 7882 R-GGA-389083 https://reactome.org/PathwayBrowser/#/R-GGA-389083 Autophosphorylation of PDGF alpha receptors IEA Gallus gallus 7882 R-GGA-9674093 https://reactome.org/PathwayBrowser/#/R-GGA-9674093 PDGFRs bind type I TKI IEA Gallus gallus 7882 R-HSA-389083 https://reactome.org/PathwayBrowser/#/R-HSA-389083 Autophosphorylation of PDGF alpha receptors TAS Homo sapiens 7882 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 7882 R-HSA-9674093 https://reactome.org/PathwayBrowser/#/R-HSA-9674093 PDGFRs bind type I TKI TAS Homo sapiens 7882 R-HSA-9674427 https://reactome.org/PathwayBrowser/#/R-HSA-9674427 PDGFR mutants bind type I TKIs TAS Homo sapiens 7882 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 7882 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 7882 R-HSA-9702583 https://reactome.org/PathwayBrowser/#/R-HSA-9702583 crenolanib-resistant FLT3 mutants don't bind crenolanib TAS Homo sapiens 7882 R-MMU-389083 https://reactome.org/PathwayBrowser/#/R-MMU-389083 Autophosphorylation of PDGF alpha receptors IEA Mus musculus 7882 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 7882 R-MMU-9674093 https://reactome.org/PathwayBrowser/#/R-MMU-9674093 PDGFRs bind type I TKI IEA Mus musculus 7882 R-RNO-389083 https://reactome.org/PathwayBrowser/#/R-RNO-389083 Autophosphorylation of PDGF alpha receptors IEA Rattus norvegicus 7882 R-RNO-9674093 https://reactome.org/PathwayBrowser/#/R-RNO-9674093 PDGFRs bind type I TKI IEA Rattus norvegicus 7882 R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa 7882 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 7882 R-SSC-9674093 https://reactome.org/PathwayBrowser/#/R-SSC-9674093 PDGFRs bind type I TKI IEA Sus scrofa 7883 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 7883 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 7883 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 7883 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 7883 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 7883 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 7883 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 7883 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 7883 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 7883 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 7883 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 7883 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 7883 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 7883 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 7883 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 7883 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 7883 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 7883 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 7883 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 7883 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 7883 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 7883 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 7883 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 7901 R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 7901 R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 7901 R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 7901 R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 7901 R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 7901 R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 7901 R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 7901 R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 7901 R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 7901 R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 7901 R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 7901 R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 7904 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 7904 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 7904 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 7904 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 7904 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 7904 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 7904 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 7904 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 7904 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 7904 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 7904 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 7904 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 7904 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 7904 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 7904 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 7904 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 7904 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 7904 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 7908 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 7921 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 7921 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 7921 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 7921 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 7921 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 7921 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 7921 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 7921 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 7921 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 7921 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 7921 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 7921 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 7921 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 7921 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 7921 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 7921 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 7921 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 7921 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 7932 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 7932 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 7932 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 7932 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 7932 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 7932 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 7932 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 7932 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 7932 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 7932 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 7932 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 7932 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 7932 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 7932 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 7932 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 7932 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 7932 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 7932 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 7934 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 7934 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 7934 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 7934 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 7934 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 7934 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 7934 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 7934 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 7934 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 7934 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 7934 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 7934 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 7934 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 7934 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 7934 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 7934 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 7934 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 7934 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 7934 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 7934 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 7934 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 7934 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 7934 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 7934 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 7934 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 7934 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 7934 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 7934 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 7934 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 7935 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 7935 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 7935 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 7935 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 7935 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 7935 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 7935 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 7935 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 7935 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 7935 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 7935 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 7935 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 7935 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 7935 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 7935 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 7935 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 7935 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 7935 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 7938 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 7938 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 7938 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 7938 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 7938 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 7938 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 7938 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 7938 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 7938 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 7938 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 7938 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 7938 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 7938 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 7938 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 7938 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 7938 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 7938 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 7938 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 7941 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 7942 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 7942 R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 7942 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 7942 R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 7942 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 7942 R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 7942 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 7942 R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 7942 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 7942 R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 7942 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 7942 R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 7942 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 7942 R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 7942 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 7942 R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 7942 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 7942 R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 7944 R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 7944 R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 7944 R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 7944 R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 7944 R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 7944 R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 7944 R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 7944 R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 7944 R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 7944 R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 7944 R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 7944 R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 7944 R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 7944 R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 7944 R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 7944 R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 7944 R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 7944 R-HSA-9665315 https://reactome.org/PathwayBrowser/#/R-HSA-9665315 ERBB2 T733I does not bind tesevatinib TAS Homo sapiens 7944 R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 7944 R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 7944 R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 7944 R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 7944 R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 7944 R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 7945 R-HSA-2400010 https://reactome.org/PathwayBrowser/#/R-HSA-2400010 AKT inhibitors block AKT membrane recruitment TAS Homo sapiens 7948 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 7948 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 7948 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 7948 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 7948 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 7948 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 7948 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 7948 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 7948 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 7948 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 7948 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 7948 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 7948 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 7948 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 7948 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 7948 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 7948 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 7948 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 7950 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 7951 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 7953 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 7953 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 7953 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 7953 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 7953 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 7953 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 7953 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 7953 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 7953 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 7953 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 7953 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 7953 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 7953 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 7953 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 7953 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 7953 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 7953 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 7953 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 7956 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 7956 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 7956 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 7956 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 7956 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 7956 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 7956 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 7956 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 7956 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 7956 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 7956 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 7956 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 7956 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 7956 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 7956 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 7956 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 7956 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 7956 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 7958 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 7958 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 7958 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 7962 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 7962 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 7962 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 7962 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 7962 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 7962 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 7962 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 7962 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 7962 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 7962 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 7962 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 7962 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 7962 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 7962 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 7962 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 7962 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 7962 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 7962 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 7963 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 7964 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 7999 R-BTA-1067667 https://reactome.org/PathwayBrowser/#/R-BTA-1067667 IL6 binds IL6R IEA Bos taurus 7999 R-BTA-9681294 https://reactome.org/PathwayBrowser/#/R-BTA-9681294 IL6R binds IL6R inhibitors IEA Bos taurus 7999 R-CEL-9681294 https://reactome.org/PathwayBrowser/#/R-CEL-9681294 IL6R binds IL6R inhibitors IEA Caenorhabditis elegans 7999 R-CFA-1067667 https://reactome.org/PathwayBrowser/#/R-CFA-1067667 IL6 binds IL6R IEA Canis familiaris 7999 R-CFA-9681294 https://reactome.org/PathwayBrowser/#/R-CFA-9681294 IL6R binds IL6R inhibitors IEA Canis familiaris 7999 R-DRE-1067667 https://reactome.org/PathwayBrowser/#/R-DRE-1067667 IL6 binds IL6R IEA Danio rerio 7999 R-DRE-9681294 https://reactome.org/PathwayBrowser/#/R-DRE-9681294 IL6R binds IL6R inhibitors IEA Danio rerio 7999 R-GGA-1067667 https://reactome.org/PathwayBrowser/#/R-GGA-1067667 IL6 binds IL6R IEA Gallus gallus 7999 R-GGA-9681294 https://reactome.org/PathwayBrowser/#/R-GGA-9681294 IL6R binds IL6R inhibitors IEA Gallus gallus 7999 R-HSA-1067667 https://reactome.org/PathwayBrowser/#/R-HSA-1067667 IL6 binds IL6R TAS Homo sapiens 7999 R-HSA-9681294 https://reactome.org/PathwayBrowser/#/R-HSA-9681294 IL6R binds IL6R inhibitors TAS Homo sapiens 7999 R-MMU-1067667 https://reactome.org/PathwayBrowser/#/R-MMU-1067667 IL6 binds IL6R IEA Mus musculus 7999 R-MMU-9681294 https://reactome.org/PathwayBrowser/#/R-MMU-9681294 IL6R binds IL6R inhibitors IEA Mus musculus 7999 R-RNO-1067667 https://reactome.org/PathwayBrowser/#/R-RNO-1067667 IL6 binds IL6R IEA Rattus norvegicus 7999 R-RNO-9681294 https://reactome.org/PathwayBrowser/#/R-RNO-9681294 IL6R binds IL6R inhibitors IEA Rattus norvegicus 8014 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 8014 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 8014 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 8015 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 8015 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 8015 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 8016 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 8016 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 8016 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 8017 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 8017 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 8017 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 8018 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 8018 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 8018 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 8019 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 8019 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 8019 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 8024 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 8024 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 8024 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 8024 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 8024 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 8024 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 8024 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 8024 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 8024 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 8024 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 8024 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 8024 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 8024 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 8024 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 8024 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 8024 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 8024 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 8024 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 8024 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 8024 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 8024 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 8025 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 8025 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 8025 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 8025 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 8025 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 8025 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 8025 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 8025 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 8025 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 8025 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 8025 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 8025 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 8025 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 8025 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 8025 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 8025 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 8025 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 8025 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 8025 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 8025 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 8025 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 8026 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 8026 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 8026 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 8026 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 8026 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 8026 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 8026 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 8026 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 8026 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 8026 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 8026 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 8026 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 8026 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 8026 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 8026 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 8026 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 8026 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 8026 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 8026 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 8026 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 8026 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 8028 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 8028 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 8028 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 8028 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 8028 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 8028 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 8028 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 8028 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 8028 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 8028 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 8028 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 8028 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 8028 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 8028 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 8028 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 8028 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 8028 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 8028 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 8028 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 8028 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 8028 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 8030 R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 8030 R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 8030 R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 8030 R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 8030 R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 8030 R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 8030 R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 8030 R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 8030 R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 8030 R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 8030 R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 8030 R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 8030 R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 8030 R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 8030 R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 8030 R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 8030 R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 8030 R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 8030 R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 8030 R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 8030 R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 8035 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 8035 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 8035 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 8035 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 8035 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 8035 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 8035 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 8035 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 8035 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 8035 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 8035 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 8035 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 8035 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 8035 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 8035 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 8035 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 8035 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 8035 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 8035 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 8035 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 8035 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 8035 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 8035 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 8035 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 8035 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 8035 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 8035 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 8035 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 8035 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 8035 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 8035 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 8035 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 8035 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 8035 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 8035 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 8035 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 8035 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 8056 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 8056 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 8056 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 8056 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 8056 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 8056 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 8056 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 8056 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 8056 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 8056 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 8056 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 8056 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 8056 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 8056 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 8056 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 8056 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 8056 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 8056 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 8097 R-HSA-2023462 https://reactome.org/PathwayBrowser/#/R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers TAS Homo sapiens 8182 R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 8182 R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 8182 R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 8182 R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 8182 R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 8182 R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 8182 R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 8182 R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 8182 R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 8182 R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 8203 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 8203 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 8203 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 8203 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 8203 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 8203 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 8203 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 8203 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 8203 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 8203 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 8203 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 8203 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 8203 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 8203 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 8203 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 8203 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 8203 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 8203 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 8290 R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 8290 R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 8290 R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 8290 R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 8290 R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 8290 R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 8290 R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 8290 R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 8290 R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 8290 R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 8290 R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 8290 R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 8290 R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 8290 R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 8290 R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 8290 R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 8290 R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 8291 R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus 8291 R-CFA-9677929 https://reactome.org/PathwayBrowser/#/R-CFA-9677929 MAOB inhibitors bind MAOB:FAD IEA Canis familiaris 8291 R-DDI-9677929 https://reactome.org/PathwayBrowser/#/R-DDI-9677929 MAOB inhibitors bind MAOB:FAD IEA Dictyostelium discoideum 8291 R-DRE-9677929 https://reactome.org/PathwayBrowser/#/R-DRE-9677929 MAOB inhibitors bind MAOB:FAD IEA Danio rerio 8291 R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus 8291 R-HSA-9677929 https://reactome.org/PathwayBrowser/#/R-HSA-9677929 MAOB inhibitors bind MAOB:FAD TAS Homo sapiens 8291 R-MMU-9677929 https://reactome.org/PathwayBrowser/#/R-MMU-9677929 MAOB inhibitors bind MAOB:FAD IEA Mus musculus 8291 R-RNO-9677929 https://reactome.org/PathwayBrowser/#/R-RNO-9677929 MAOB inhibitors bind MAOB:FAD IEA Rattus norvegicus 8291 R-SSC-9677929 https://reactome.org/PathwayBrowser/#/R-SSC-9677929 MAOB inhibitors bind MAOB:FAD IEA Sus scrofa 8291 R-XTR-9677929 https://reactome.org/PathwayBrowser/#/R-XTR-9677929 MAOB inhibitors bind MAOB:FAD IEA Xenopus tropicalis 8293 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 8293 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 8293 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 8293 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 8293 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 8293 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 8293 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 8293 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 8293 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 8293 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 8293 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 8293 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 8293 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 8293 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 8293 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 8293 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 8293 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 8293 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 83 R-BTA-8866277 https://reactome.org/PathwayBrowser/#/R-BTA-8866277 AP-2 directly binds some endocytic cargo IEA Bos taurus 83 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 83 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 83 R-BTA-9681616 https://reactome.org/PathwayBrowser/#/R-BTA-9681616 AP2 binds chlorpromazine IEA Bos taurus 83 R-CEL-8866277 https://reactome.org/PathwayBrowser/#/R-CEL-8866277 AP-2 directly binds some endocytic cargo IEA Caenorhabditis elegans 83 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 83 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 83 R-CEL-9681616 https://reactome.org/PathwayBrowser/#/R-CEL-9681616 AP2 binds chlorpromazine IEA Caenorhabditis elegans 83 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 83 R-CFA-8866277 https://reactome.org/PathwayBrowser/#/R-CFA-8866277 AP-2 directly binds some endocytic cargo IEA Canis familiaris 83 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 83 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 83 R-CFA-9681616 https://reactome.org/PathwayBrowser/#/R-CFA-9681616 AP2 binds chlorpromazine IEA Canis familiaris 83 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 83 R-DDI-8866277 https://reactome.org/PathwayBrowser/#/R-DDI-8866277 AP-2 directly binds some endocytic cargo IEA Dictyostelium discoideum 83 R-DDI-9681616 https://reactome.org/PathwayBrowser/#/R-DDI-9681616 AP2 binds chlorpromazine IEA Dictyostelium discoideum 83 R-DME-8866277 https://reactome.org/PathwayBrowser/#/R-DME-8866277 AP-2 directly binds some endocytic cargo IEA Drosophila melanogaster 83 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 83 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 83 R-DME-9681616 https://reactome.org/PathwayBrowser/#/R-DME-9681616 AP2 binds chlorpromazine IEA Drosophila melanogaster 83 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 83 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 83 R-DRE-9681616 https://reactome.org/PathwayBrowser/#/R-DRE-9681616 AP2 binds chlorpromazine IEA Danio rerio 83 R-GGA-8866277 https://reactome.org/PathwayBrowser/#/R-GGA-8866277 AP-2 directly binds some endocytic cargo IEA Gallus gallus 83 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 83 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 83 R-GGA-9681616 https://reactome.org/PathwayBrowser/#/R-GGA-9681616 AP2 binds chlorpromazine IEA Gallus gallus 83 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 83 R-HSA-8866277 https://reactome.org/PathwayBrowser/#/R-HSA-8866277 AP-2 directly binds some endocytic cargo TAS Homo sapiens 83 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 83 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 83 R-HSA-9681616 https://reactome.org/PathwayBrowser/#/R-HSA-9681616 AP2 binds chlorpromazine TAS Homo sapiens 83 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 83 R-MMU-8866277 https://reactome.org/PathwayBrowser/#/R-MMU-8866277 AP-2 directly binds some endocytic cargo IEA Mus musculus 83 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 83 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 83 R-MMU-9681616 https://reactome.org/PathwayBrowser/#/R-MMU-9681616 AP2 binds chlorpromazine IEA Mus musculus 83 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 83 R-PFA-8866277 https://reactome.org/PathwayBrowser/#/R-PFA-8866277 AP-2 directly binds some endocytic cargo IEA Plasmodium falciparum 83 R-PFA-9681616 https://reactome.org/PathwayBrowser/#/R-PFA-9681616 AP2 binds chlorpromazine IEA Plasmodium falciparum 83 R-RNO-8866277 https://reactome.org/PathwayBrowser/#/R-RNO-8866277 AP-2 directly binds some endocytic cargo IEA Rattus norvegicus 83 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 83 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 83 R-RNO-9681616 https://reactome.org/PathwayBrowser/#/R-RNO-9681616 AP2 binds chlorpromazine IEA Rattus norvegicus 83 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 83 R-SCE-8866277 https://reactome.org/PathwayBrowser/#/R-SCE-8866277 AP-2 directly binds some endocytic cargo IEA Saccharomyces cerevisiae 83 R-SCE-9681616 https://reactome.org/PathwayBrowser/#/R-SCE-9681616 AP2 binds chlorpromazine IEA Saccharomyces cerevisiae 83 R-SPO-8866277 https://reactome.org/PathwayBrowser/#/R-SPO-8866277 AP-2 directly binds some endocytic cargo IEA Schizosaccharomyces pombe 83 R-SPO-9681616 https://reactome.org/PathwayBrowser/#/R-SPO-9681616 AP2 binds chlorpromazine IEA Schizosaccharomyces pombe 83 R-SSC-8866277 https://reactome.org/PathwayBrowser/#/R-SSC-8866277 AP-2 directly binds some endocytic cargo IEA Sus scrofa 83 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 83 R-SSC-9681616 https://reactome.org/PathwayBrowser/#/R-SSC-9681616 AP2 binds chlorpromazine IEA Sus scrofa 83 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 83 R-XTR-8866277 https://reactome.org/PathwayBrowser/#/R-XTR-8866277 AP-2 directly binds some endocytic cargo IEA Xenopus tropicalis 83 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 83 R-XTR-9681616 https://reactome.org/PathwayBrowser/#/R-XTR-9681616 AP2 binds chlorpromazine IEA Xenopus tropicalis 83 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 8311 R-BTA-9707353 https://reactome.org/PathwayBrowser/#/R-BTA-9707353 CYP19A1 binds Aromatase inhibitors IEA Bos taurus 8311 R-CEL-9707353 https://reactome.org/PathwayBrowser/#/R-CEL-9707353 CYP19A1 binds Aromatase inhibitors IEA Caenorhabditis elegans 8311 R-CFA-9707353 https://reactome.org/PathwayBrowser/#/R-CFA-9707353 CYP19A1 binds Aromatase inhibitors IEA Canis familiaris 8311 R-DME-9707353 https://reactome.org/PathwayBrowser/#/R-DME-9707353 CYP19A1 binds Aromatase inhibitors IEA Drosophila melanogaster 8311 R-DRE-9707353 https://reactome.org/PathwayBrowser/#/R-DRE-9707353 CYP19A1 binds Aromatase inhibitors IEA Danio rerio 8311 R-GGA-9707353 https://reactome.org/PathwayBrowser/#/R-GGA-9707353 CYP19A1 binds Aromatase inhibitors IEA Gallus gallus 8311 R-HSA-9707353 https://reactome.org/PathwayBrowser/#/R-HSA-9707353 CYP19A1 binds Aromatase inhibitors TAS Homo sapiens 8311 R-MMU-9707353 https://reactome.org/PathwayBrowser/#/R-MMU-9707353 CYP19A1 binds Aromatase inhibitors IEA Mus musculus 8311 R-RNO-9707353 https://reactome.org/PathwayBrowser/#/R-RNO-9707353 CYP19A1 binds Aromatase inhibitors IEA Rattus norvegicus 8311 R-SSC-9707353 https://reactome.org/PathwayBrowser/#/R-SSC-9707353 CYP19A1 binds Aromatase inhibitors IEA Sus scrofa 8311 R-XTR-9707353 https://reactome.org/PathwayBrowser/#/R-XTR-9707353 CYP19A1 binds Aromatase inhibitors IEA Xenopus tropicalis 8312 R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 8312 R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 8312 R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 8312 R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 8312 R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 8312 R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 8312 R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 8312 R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 8318 R-BTA-9692376 https://reactome.org/PathwayBrowser/#/R-BTA-9692376 BCL2 binds BCL2 antagonists IEA Bos taurus 8318 R-CEL-9692376 https://reactome.org/PathwayBrowser/#/R-CEL-9692376 BCL2 binds BCL2 antagonists IEA Caenorhabditis elegans 8318 R-CFA-9692376 https://reactome.org/PathwayBrowser/#/R-CFA-9692376 BCL2 binds BCL2 antagonists IEA Canis familiaris 8318 R-DRE-9692376 https://reactome.org/PathwayBrowser/#/R-DRE-9692376 BCL2 binds BCL2 antagonists IEA Danio rerio 8318 R-GGA-9692376 https://reactome.org/PathwayBrowser/#/R-GGA-9692376 BCL2 binds BCL2 antagonists IEA Gallus gallus 8318 R-HSA-9692376 https://reactome.org/PathwayBrowser/#/R-HSA-9692376 BCL2 binds BCL2 antagonists TAS Homo sapiens 8318 R-MMU-9692376 https://reactome.org/PathwayBrowser/#/R-MMU-9692376 BCL2 binds BCL2 antagonists IEA Mus musculus 8318 R-SSC-9692376 https://reactome.org/PathwayBrowser/#/R-SSC-9692376 BCL2 binds BCL2 antagonists IEA Sus scrofa 8318 R-XTR-9692376 https://reactome.org/PathwayBrowser/#/R-XTR-9692376 BCL2 binds BCL2 antagonists IEA Xenopus tropicalis 8319 R-BTA-9692376 https://reactome.org/PathwayBrowser/#/R-BTA-9692376 BCL2 binds BCL2 antagonists IEA Bos taurus 8319 R-CEL-9692376 https://reactome.org/PathwayBrowser/#/R-CEL-9692376 BCL2 binds BCL2 antagonists IEA Caenorhabditis elegans 8319 R-CFA-9692376 https://reactome.org/PathwayBrowser/#/R-CFA-9692376 BCL2 binds BCL2 antagonists IEA Canis familiaris 8319 R-DRE-9692376 https://reactome.org/PathwayBrowser/#/R-DRE-9692376 BCL2 binds BCL2 antagonists IEA Danio rerio 8319 R-GGA-9692376 https://reactome.org/PathwayBrowser/#/R-GGA-9692376 BCL2 binds BCL2 antagonists IEA Gallus gallus 8319 R-HSA-9692376 https://reactome.org/PathwayBrowser/#/R-HSA-9692376 BCL2 binds BCL2 antagonists TAS Homo sapiens 8319 R-MMU-9692376 https://reactome.org/PathwayBrowser/#/R-MMU-9692376 BCL2 binds BCL2 antagonists IEA Mus musculus 8319 R-SSC-9692376 https://reactome.org/PathwayBrowser/#/R-SSC-9692376 BCL2 binds BCL2 antagonists IEA Sus scrofa 8319 R-XTR-9692376 https://reactome.org/PathwayBrowser/#/R-XTR-9692376 BCL2 binds BCL2 antagonists IEA Xenopus tropicalis 8320 R-BTA-9692376 https://reactome.org/PathwayBrowser/#/R-BTA-9692376 BCL2 binds BCL2 antagonists IEA Bos taurus 8320 R-CEL-9692376 https://reactome.org/PathwayBrowser/#/R-CEL-9692376 BCL2 binds BCL2 antagonists IEA Caenorhabditis elegans 8320 R-CFA-9692376 https://reactome.org/PathwayBrowser/#/R-CFA-9692376 BCL2 binds BCL2 antagonists IEA Canis familiaris 8320 R-DRE-9692376 https://reactome.org/PathwayBrowser/#/R-DRE-9692376 BCL2 binds BCL2 antagonists IEA Danio rerio 8320 R-GGA-9692376 https://reactome.org/PathwayBrowser/#/R-GGA-9692376 BCL2 binds BCL2 antagonists IEA Gallus gallus 8320 R-HSA-9692376 https://reactome.org/PathwayBrowser/#/R-HSA-9692376 BCL2 binds BCL2 antagonists TAS Homo sapiens 8320 R-MMU-9692376 https://reactome.org/PathwayBrowser/#/R-MMU-9692376 BCL2 binds BCL2 antagonists IEA Mus musculus 8320 R-SSC-9692376 https://reactome.org/PathwayBrowser/#/R-SSC-9692376 BCL2 binds BCL2 antagonists IEA Sus scrofa 8320 R-XTR-9692376 https://reactome.org/PathwayBrowser/#/R-XTR-9692376 BCL2 binds BCL2 antagonists IEA Xenopus tropicalis 8321 R-BTA-9734535 https://reactome.org/PathwayBrowser/#/R-BTA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Bos taurus 8321 R-BTA-9734540 https://reactome.org/PathwayBrowser/#/R-BTA-9734540 ACLY tetramer binds ETC-1002-CoA IEA Bos taurus 8321 R-CEL-9734535 https://reactome.org/PathwayBrowser/#/R-CEL-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Caenorhabditis elegans 8321 R-CEL-9734540 https://reactome.org/PathwayBrowser/#/R-CEL-9734540 ACLY tetramer binds ETC-1002-CoA IEA Caenorhabditis elegans 8321 R-CFA-9734535 https://reactome.org/PathwayBrowser/#/R-CFA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Canis familiaris 8321 R-CFA-9734540 https://reactome.org/PathwayBrowser/#/R-CFA-9734540 ACLY tetramer binds ETC-1002-CoA IEA Canis familiaris 8321 R-DDI-9734540 https://reactome.org/PathwayBrowser/#/R-DDI-9734540 ACLY tetramer binds ETC-1002-CoA IEA Dictyostelium discoideum 8321 R-DME-9734535 https://reactome.org/PathwayBrowser/#/R-DME-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Drosophila melanogaster 8321 R-DME-9734540 https://reactome.org/PathwayBrowser/#/R-DME-9734540 ACLY tetramer binds ETC-1002-CoA IEA Drosophila melanogaster 8321 R-DRE-9734540 https://reactome.org/PathwayBrowser/#/R-DRE-9734540 ACLY tetramer binds ETC-1002-CoA IEA Danio rerio 8321 R-GGA-9734535 https://reactome.org/PathwayBrowser/#/R-GGA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Gallus gallus 8321 R-GGA-9734540 https://reactome.org/PathwayBrowser/#/R-GGA-9734540 ACLY tetramer binds ETC-1002-CoA IEA Gallus gallus 8321 R-HSA-9734535 https://reactome.org/PathwayBrowser/#/R-HSA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA TAS Homo sapiens 8321 R-HSA-9734540 https://reactome.org/PathwayBrowser/#/R-HSA-9734540 ACLY tetramer binds ETC-1002-CoA TAS Homo sapiens 8321 R-MMU-9734535 https://reactome.org/PathwayBrowser/#/R-MMU-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Mus musculus 8321 R-MMU-9734540 https://reactome.org/PathwayBrowser/#/R-MMU-9734540 ACLY tetramer binds ETC-1002-CoA IEA Mus musculus 8321 R-RNO-9734535 https://reactome.org/PathwayBrowser/#/R-RNO-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Rattus norvegicus 8321 R-RNO-9734540 https://reactome.org/PathwayBrowser/#/R-RNO-9734540 ACLY tetramer binds ETC-1002-CoA IEA Rattus norvegicus 8321 R-SCE-9734535 https://reactome.org/PathwayBrowser/#/R-SCE-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Saccharomyces cerevisiae 8321 R-SPO-9734540 https://reactome.org/PathwayBrowser/#/R-SPO-9734540 ACLY tetramer binds ETC-1002-CoA IEA Schizosaccharomyces pombe 8321 R-SSC-9734535 https://reactome.org/PathwayBrowser/#/R-SSC-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Sus scrofa 8321 R-SSC-9734540 https://reactome.org/PathwayBrowser/#/R-SSC-9734540 ACLY tetramer binds ETC-1002-CoA IEA Sus scrofa 8321 R-XTR-9734535 https://reactome.org/PathwayBrowser/#/R-XTR-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Xenopus tropicalis 8321 R-XTR-9734540 https://reactome.org/PathwayBrowser/#/R-XTR-9734540 ACLY tetramer binds ETC-1002-CoA IEA Xenopus tropicalis 8338 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 8338 R-BTA-9696179 https://reactome.org/PathwayBrowser/#/R-BTA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Bos taurus 8338 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 8338 R-CFA-9696179 https://reactome.org/PathwayBrowser/#/R-CFA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Canis familiaris 8338 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 8338 R-GGA-9696179 https://reactome.org/PathwayBrowser/#/R-GGA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Gallus gallus 8338 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 8338 R-HSA-9696179 https://reactome.org/PathwayBrowser/#/R-HSA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs TAS Homo sapiens 8338 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 8338 R-MMU-9696179 https://reactome.org/PathwayBrowser/#/R-MMU-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Mus musculus 8338 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 8338 R-RNO-9696179 https://reactome.org/PathwayBrowser/#/R-RNO-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Rattus norvegicus 8338 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 8338 R-SSC-9696179 https://reactome.org/PathwayBrowser/#/R-SSC-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Sus scrofa 8338 R-XTR-9696179 https://reactome.org/PathwayBrowser/#/R-XTR-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Xenopus tropicalis 8339 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 8339 R-BTA-9696179 https://reactome.org/PathwayBrowser/#/R-BTA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Bos taurus 8339 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 8339 R-CFA-9696179 https://reactome.org/PathwayBrowser/#/R-CFA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Canis familiaris 8339 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 8339 R-GGA-9696179 https://reactome.org/PathwayBrowser/#/R-GGA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Gallus gallus 8339 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 8339 R-HSA-9696179 https://reactome.org/PathwayBrowser/#/R-HSA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs TAS Homo sapiens 8339 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 8339 R-MMU-9696179 https://reactome.org/PathwayBrowser/#/R-MMU-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Mus musculus 8339 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 8339 R-RNO-9696179 https://reactome.org/PathwayBrowser/#/R-RNO-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Rattus norvegicus 8339 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 8339 R-SSC-9696179 https://reactome.org/PathwayBrowser/#/R-SSC-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Sus scrofa 8339 R-XTR-9696179 https://reactome.org/PathwayBrowser/#/R-XTR-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Xenopus tropicalis 8340 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 8340 R-BTA-9696179 https://reactome.org/PathwayBrowser/#/R-BTA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Bos taurus 8340 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 8340 R-CFA-9696179 https://reactome.org/PathwayBrowser/#/R-CFA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Canis familiaris 8340 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 8340 R-GGA-9696179 https://reactome.org/PathwayBrowser/#/R-GGA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Gallus gallus 8340 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 8340 R-HSA-9696179 https://reactome.org/PathwayBrowser/#/R-HSA-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs TAS Homo sapiens 8340 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 8340 R-MMU-9696179 https://reactome.org/PathwayBrowser/#/R-MMU-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Mus musculus 8340 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 8340 R-RNO-9696179 https://reactome.org/PathwayBrowser/#/R-RNO-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Rattus norvegicus 8340 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 8340 R-SSC-9696179 https://reactome.org/PathwayBrowser/#/R-SSC-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Sus scrofa 8340 R-XTR-9696179 https://reactome.org/PathwayBrowser/#/R-XTR-9696179 IFNAR2:JAK1:STAT2 binds type 1 interferon analogs IEA Xenopus tropicalis 8362 R-BTA-9718379 https://reactome.org/PathwayBrowser/#/R-BTA-9718379 GNRHR binds chemical antagonists IEA Bos taurus 8362 R-CEL-9718379 https://reactome.org/PathwayBrowser/#/R-CEL-9718379 GNRHR binds chemical antagonists IEA Caenorhabditis elegans 8362 R-CFA-9718379 https://reactome.org/PathwayBrowser/#/R-CFA-9718379 GNRHR binds chemical antagonists IEA Canis familiaris 8362 R-DME-9718379 https://reactome.org/PathwayBrowser/#/R-DME-9718379 GNRHR binds chemical antagonists IEA Drosophila melanogaster 8362 R-DRE-9718379 https://reactome.org/PathwayBrowser/#/R-DRE-9718379 GNRHR binds chemical antagonists IEA Danio rerio 8362 R-GGA-9718379 https://reactome.org/PathwayBrowser/#/R-GGA-9718379 GNRHR binds chemical antagonists IEA Gallus gallus 8362 R-HSA-9718379 https://reactome.org/PathwayBrowser/#/R-HSA-9718379 GNRHR binds chemical antagonists TAS Homo sapiens 8362 R-MMU-9718379 https://reactome.org/PathwayBrowser/#/R-MMU-9718379 GNRHR binds chemical antagonists IEA Mus musculus 8362 R-RNO-9718379 https://reactome.org/PathwayBrowser/#/R-RNO-9718379 GNRHR binds chemical antagonists IEA Rattus norvegicus 8362 R-SSC-9718379 https://reactome.org/PathwayBrowser/#/R-SSC-9718379 GNRHR binds chemical antagonists IEA Sus scrofa 8362 R-XTR-9718379 https://reactome.org/PathwayBrowser/#/R-XTR-9718379 GNRHR binds chemical antagonists IEA Xenopus tropicalis 8371 R-BTA-9679477 https://reactome.org/PathwayBrowser/#/R-BTA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Bos taurus 8371 R-BTA-9691215 https://reactome.org/PathwayBrowser/#/R-BTA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Bos taurus 8371 R-CFA-9679477 https://reactome.org/PathwayBrowser/#/R-CFA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Canis familiaris 8371 R-CFA-9691215 https://reactome.org/PathwayBrowser/#/R-CFA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Canis familiaris 8371 R-DRE-9679477 https://reactome.org/PathwayBrowser/#/R-DRE-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Danio rerio 8371 R-DRE-9691215 https://reactome.org/PathwayBrowser/#/R-DRE-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Danio rerio 8371 R-GGA-9679477 https://reactome.org/PathwayBrowser/#/R-GGA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Gallus gallus 8371 R-GGA-9691215 https://reactome.org/PathwayBrowser/#/R-GGA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Gallus gallus 8371 R-HSA-9679477 https://reactome.org/PathwayBrowser/#/R-HSA-9679477 VEGFA-165 dimer binds VEGFA inhibitors TAS Homo sapiens 8371 R-HSA-9691215 https://reactome.org/PathwayBrowser/#/R-HSA-9691215 VEGFA-165 dimer binds VEGFR2 dimer TAS Homo sapiens 8371 R-MMU-9679477 https://reactome.org/PathwayBrowser/#/R-MMU-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Mus musculus 8371 R-MMU-9691215 https://reactome.org/PathwayBrowser/#/R-MMU-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Mus musculus 8371 R-RNO-9679477 https://reactome.org/PathwayBrowser/#/R-RNO-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Rattus norvegicus 8371 R-RNO-9691215 https://reactome.org/PathwayBrowser/#/R-RNO-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Rattus norvegicus 8371 R-SSC-9679477 https://reactome.org/PathwayBrowser/#/R-SSC-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Sus scrofa 8371 R-SSC-9691215 https://reactome.org/PathwayBrowser/#/R-SSC-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Sus scrofa 8371 R-XTR-9679477 https://reactome.org/PathwayBrowser/#/R-XTR-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Xenopus tropicalis 8371 R-XTR-9691215 https://reactome.org/PathwayBrowser/#/R-XTR-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Xenopus tropicalis 8375 R-BTA-9703895 https://reactome.org/PathwayBrowser/#/R-BTA-9703895 CASR binds CASR agonists IEA Bos taurus 8375 R-CFA-9703895 https://reactome.org/PathwayBrowser/#/R-CFA-9703895 CASR binds CASR agonists IEA Canis familiaris 8375 R-GGA-9703895 https://reactome.org/PathwayBrowser/#/R-GGA-9703895 CASR binds CASR agonists IEA Gallus gallus 8375 R-HSA-9703895 https://reactome.org/PathwayBrowser/#/R-HSA-9703895 CASR binds CASR agonists TAS Homo sapiens 8375 R-MMU-9703895 https://reactome.org/PathwayBrowser/#/R-MMU-9703895 CASR binds CASR agonists IEA Mus musculus 8375 R-RNO-9703895 https://reactome.org/PathwayBrowser/#/R-RNO-9703895 CASR binds CASR agonists IEA Rattus norvegicus 8375 R-SSC-9703895 https://reactome.org/PathwayBrowser/#/R-SSC-9703895 CASR binds CASR agonists IEA Sus scrofa 8375 R-XTR-9703895 https://reactome.org/PathwayBrowser/#/R-XTR-9703895 CASR binds CASR agonists IEA Xenopus tropicalis 8376 R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 8376 R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 8376 R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 8376 R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 8376 R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 8376 R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 8376 R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 8376 R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 8402 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 8402 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 8402 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 8402 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 8402 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 8402 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 8402 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 8402 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 8402 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 8402 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 8402 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 8402 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 8478 R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 8478 R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 8478 R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 85 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 85 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 85 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 85 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 85 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 85 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 85 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 85 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 85 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 85 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 85 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 85 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 85 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 85 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 85 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 85 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 85 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 85 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 86 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 86 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 86 R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 86 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 86 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 86 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 86 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 86 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 86 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 86 R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 86 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 86 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 86 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 86 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 86 R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 86 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 86 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 86 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 86 R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 86 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 86 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 86 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 86 R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 86 R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 86 R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 86 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 86 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 86 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 86 R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 86 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 86 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 86 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 86 R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 86 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 86 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 86 R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 86 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 86 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 8601 R-HSA-5210912 https://reactome.org/PathwayBrowser/#/R-HSA-5210912 Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) TAS Homo sapiens 8601 R-HSA-5210935 https://reactome.org/PathwayBrowser/#/R-HSA-5210935 Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) TAS Homo sapiens 8601 R-HSA-9683546 https://reactome.org/PathwayBrowser/#/R-HSA-9683546 FURIN binds furin inhibitors TAS Homo sapiens 87 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 87 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 87 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 87 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 87 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 87 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 87 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 87 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 87 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 87 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 8708 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 8708 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 8708 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 8708 R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 8708 R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 8708 R-HSA-9702589 https://reactome.org/PathwayBrowser/#/R-HSA-9702589 gilteritinib-resistant FLT3 mutants don't bind gilteritinib TAS Homo sapiens 8708 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 8708 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 8709 R-BTA-9678854 https://reactome.org/PathwayBrowser/#/R-BTA-9678854 S1PR1 binds S1PR1 agonists IEA Bos taurus 8709 R-BTA-9690449 https://reactome.org/PathwayBrowser/#/R-BTA-9690449 S1PR1 bind S1P IEA Bos taurus 8709 R-CFA-9678854 https://reactome.org/PathwayBrowser/#/R-CFA-9678854 S1PR1 binds S1PR1 agonists IEA Canis familiaris 8709 R-CFA-9690449 https://reactome.org/PathwayBrowser/#/R-CFA-9690449 S1PR1 bind S1P IEA Canis familiaris 8709 R-DRE-9678854 https://reactome.org/PathwayBrowser/#/R-DRE-9678854 S1PR1 binds S1PR1 agonists IEA Danio rerio 8709 R-DRE-9690449 https://reactome.org/PathwayBrowser/#/R-DRE-9690449 S1PR1 bind S1P IEA Danio rerio 8709 R-GGA-9678854 https://reactome.org/PathwayBrowser/#/R-GGA-9678854 S1PR1 binds S1PR1 agonists IEA Gallus gallus 8709 R-GGA-9690449 https://reactome.org/PathwayBrowser/#/R-GGA-9690449 S1PR1 bind S1P IEA Gallus gallus 8709 R-HSA-9678854 https://reactome.org/PathwayBrowser/#/R-HSA-9678854 S1PR1 binds S1PR1 agonists TAS Homo sapiens 8709 R-HSA-9690449 https://reactome.org/PathwayBrowser/#/R-HSA-9690449 S1PR1 bind S1P TAS Homo sapiens 8709 R-MMU-9678854 https://reactome.org/PathwayBrowser/#/R-MMU-9678854 S1PR1 binds S1PR1 agonists IEA Mus musculus 8709 R-MMU-9690449 https://reactome.org/PathwayBrowser/#/R-MMU-9690449 S1PR1 bind S1P IEA Mus musculus 8709 R-RNO-9678854 https://reactome.org/PathwayBrowser/#/R-RNO-9678854 S1PR1 binds S1PR1 agonists IEA Rattus norvegicus 8709 R-RNO-9690449 https://reactome.org/PathwayBrowser/#/R-RNO-9690449 S1PR1 bind S1P IEA Rattus norvegicus 8709 R-SSC-9678854 https://reactome.org/PathwayBrowser/#/R-SSC-9678854 S1PR1 binds S1PR1 agonists IEA Sus scrofa 8709 R-SSC-9690449 https://reactome.org/PathwayBrowser/#/R-SSC-9690449 S1PR1 bind S1P IEA Sus scrofa 8709 R-XTR-9678854 https://reactome.org/PathwayBrowser/#/R-XTR-9678854 S1PR1 binds S1PR1 agonists IEA Xenopus tropicalis 8709 R-XTR-9690449 https://reactome.org/PathwayBrowser/#/R-XTR-9690449 S1PR1 bind S1P IEA Xenopus tropicalis 8710 R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 8710 R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 8710 R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 8710 R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 8710 R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 8710 R-HSA-9702607 https://reactome.org/PathwayBrowser/#/R-HSA-9702607 pexidartinib-resistant FLT3 mutants don't bind pexidartinib TAS Homo sapiens 8710 R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 8710 R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 8711 R-BTA-9691621 https://reactome.org/PathwayBrowser/#/R-BTA-9691621 C5 binds C5 inhibitors IEA Bos taurus 8711 R-CFA-9691621 https://reactome.org/PathwayBrowser/#/R-CFA-9691621 C5 binds C5 inhibitors IEA Canis familiaris 8711 R-GGA-9691621 https://reactome.org/PathwayBrowser/#/R-GGA-9691621 C5 binds C5 inhibitors IEA Gallus gallus 8711 R-HSA-9691621 https://reactome.org/PathwayBrowser/#/R-HSA-9691621 C5 binds C5 inhibitors TAS Homo sapiens 8711 R-MMU-9691621 https://reactome.org/PathwayBrowser/#/R-MMU-9691621 C5 binds C5 inhibitors IEA Mus musculus 8711 R-RNO-9691621 https://reactome.org/PathwayBrowser/#/R-RNO-9691621 C5 binds C5 inhibitors IEA Rattus norvegicus 8711 R-SSC-9691621 https://reactome.org/PathwayBrowser/#/R-SSC-9691621 C5 binds C5 inhibitors IEA Sus scrofa 8713 R-BTA-9679477 https://reactome.org/PathwayBrowser/#/R-BTA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Bos taurus 8713 R-BTA-9691215 https://reactome.org/PathwayBrowser/#/R-BTA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Bos taurus 8713 R-CFA-9679477 https://reactome.org/PathwayBrowser/#/R-CFA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Canis familiaris 8713 R-CFA-9691215 https://reactome.org/PathwayBrowser/#/R-CFA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Canis familiaris 8713 R-DRE-9679477 https://reactome.org/PathwayBrowser/#/R-DRE-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Danio rerio 8713 R-DRE-9691215 https://reactome.org/PathwayBrowser/#/R-DRE-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Danio rerio 8713 R-GGA-9679477 https://reactome.org/PathwayBrowser/#/R-GGA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Gallus gallus 8713 R-GGA-9691215 https://reactome.org/PathwayBrowser/#/R-GGA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Gallus gallus 8713 R-HSA-9679477 https://reactome.org/PathwayBrowser/#/R-HSA-9679477 VEGFA-165 dimer binds VEGFA inhibitors TAS Homo sapiens 8713 R-HSA-9691215 https://reactome.org/PathwayBrowser/#/R-HSA-9691215 VEGFA-165 dimer binds VEGFR2 dimer TAS Homo sapiens 8713 R-MMU-9679477 https://reactome.org/PathwayBrowser/#/R-MMU-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Mus musculus 8713 R-MMU-9691215 https://reactome.org/PathwayBrowser/#/R-MMU-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Mus musculus 8713 R-RNO-9679477 https://reactome.org/PathwayBrowser/#/R-RNO-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Rattus norvegicus 8713 R-RNO-9691215 https://reactome.org/PathwayBrowser/#/R-RNO-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Rattus norvegicus 8713 R-SSC-9679477 https://reactome.org/PathwayBrowser/#/R-SSC-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Sus scrofa 8713 R-SSC-9691215 https://reactome.org/PathwayBrowser/#/R-SSC-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Sus scrofa 8713 R-XTR-9679477 https://reactome.org/PathwayBrowser/#/R-XTR-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Xenopus tropicalis 8713 R-XTR-9691215 https://reactome.org/PathwayBrowser/#/R-XTR-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Xenopus tropicalis 8741 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 8760 R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 8760 R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 8760 R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 8760 R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 8760 R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 8760 R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 8760 R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 8760 R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 8760 R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 8760 R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 8760 R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 8760 R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 8760 R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 8760 R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 8760 R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 8760 R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 8760 R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 8760 R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 8760 R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 8760 R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 8760 R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 8760 R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 8760 R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 8760 R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 8760 R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 8760 R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 8760 R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 8760 R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 8760 R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 8760 R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 8760 R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 8760 R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 8798 R-HSA-9911461 https://reactome.org/PathwayBrowser/#/R-HSA-9911461 β-lactam antibiotics bind MrcB TAS Homo sapiens 8798 R-HSA-9911463 https://reactome.org/PathwayBrowser/#/R-HSA-9911463 MrcB elongates peptidoglycan TAS Homo sapiens 8798 R-HSA-9911512 https://reactome.org/PathwayBrowser/#/R-HSA-9911512 AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm TAS Homo sapiens 8798 R-HSA-9911515 https://reactome.org/PathwayBrowser/#/R-HSA-9911515 KPC-2 hydrolyzes cephalothin TAS Homo sapiens 8798 R-HSA-9911516 https://reactome.org/PathwayBrowser/#/R-HSA-9911516 AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region TAS Homo sapiens 8798 R-HSA-9911519 https://reactome.org/PathwayBrowser/#/R-HSA-9911519 BlaSHV-12 hydrolyzes cephalothin TAS Homo sapiens 8798 R-HSA-9914083 https://reactome.org/PathwayBrowser/#/R-HSA-9914083 MdtE:MdtF:TolC exports beta-lactams to extracellular space TAS Homo sapiens 8798 R-HSA-9914089 https://reactome.org/PathwayBrowser/#/R-HSA-9914089 MdtE:MdtF:TolC exports beta-lactams to the periplasm TAS Homo sapiens 88 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 88 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 88 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 88 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 88 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 88 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 88 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 88 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 88 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 88 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 8804 R-BTA-9678766 https://reactome.org/PathwayBrowser/#/R-BTA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Bos taurus 8804 R-BTA-9680865 https://reactome.org/PathwayBrowser/#/R-BTA-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Bos taurus 8804 R-CEL-9680865 https://reactome.org/PathwayBrowser/#/R-CEL-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Caenorhabditis elegans 8804 R-CFA-9678766 https://reactome.org/PathwayBrowser/#/R-CFA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Canis familiaris 8804 R-CFA-9680865 https://reactome.org/PathwayBrowser/#/R-CFA-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Canis familiaris 8804 R-DDI-9680865 https://reactome.org/PathwayBrowser/#/R-DDI-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Dictyostelium discoideum 8804 R-DME-9680865 https://reactome.org/PathwayBrowser/#/R-DME-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Drosophila melanogaster 8804 R-DRE-9678766 https://reactome.org/PathwayBrowser/#/R-DRE-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Danio rerio 8804 R-DRE-9680865 https://reactome.org/PathwayBrowser/#/R-DRE-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Danio rerio 8804 R-GGA-9678766 https://reactome.org/PathwayBrowser/#/R-GGA-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Gallus gallus 8804 R-GGA-9680865 https://reactome.org/PathwayBrowser/#/R-GGA-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Gallus gallus 8804 R-HSA-9678766 https://reactome.org/PathwayBrowser/#/R-HSA-9678766 CYP3A4 binds CYP3A4 inhibitors TAS Homo sapiens 8804 R-HSA-9680865 https://reactome.org/PathwayBrowser/#/R-HSA-9680865 CYP3A4, CYP2B6 bind ritonavir TAS Homo sapiens 8804 R-MMU-9678766 https://reactome.org/PathwayBrowser/#/R-MMU-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Mus musculus 8804 R-MMU-9680865 https://reactome.org/PathwayBrowser/#/R-MMU-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Mus musculus 8804 R-RNO-9678766 https://reactome.org/PathwayBrowser/#/R-RNO-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Rattus norvegicus 8804 R-RNO-9680865 https://reactome.org/PathwayBrowser/#/R-RNO-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Rattus norvegicus 8804 R-SSC-9678766 https://reactome.org/PathwayBrowser/#/R-SSC-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Sus scrofa 8804 R-SSC-9680865 https://reactome.org/PathwayBrowser/#/R-SSC-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Sus scrofa 8804 R-XTR-9678766 https://reactome.org/PathwayBrowser/#/R-XTR-9678766 CYP3A4 binds CYP3A4 inhibitors IEA Xenopus tropicalis 8804 R-XTR-9680865 https://reactome.org/PathwayBrowser/#/R-XTR-9680865 CYP3A4, CYP2B6 bind ritonavir IEA Xenopus tropicalis 8912 R-BTA-451895 https://reactome.org/PathwayBrowser/#/R-BTA-451895 IL2RG binds JAK3 IEA Bos taurus 8912 R-BTA-9679028 https://reactome.org/PathwayBrowser/#/R-BTA-9679028 JAK3 binds JAK3 inhibitors IEA Bos taurus 8912 R-BTA-9691421 https://reactome.org/PathwayBrowser/#/R-BTA-9691421 BTK binds BTK inhibitors IEA Bos taurus 8912 R-CFA-9679028 https://reactome.org/PathwayBrowser/#/R-CFA-9679028 JAK3 binds JAK3 inhibitors IEA Canis familiaris 8912 R-CFA-9691421 https://reactome.org/PathwayBrowser/#/R-CFA-9691421 BTK binds BTK inhibitors IEA Canis familiaris 8912 R-DME-9679028 https://reactome.org/PathwayBrowser/#/R-DME-9679028 JAK3 binds JAK3 inhibitors IEA Drosophila melanogaster 8912 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus 8912 R-HSA-451895 https://reactome.org/PathwayBrowser/#/R-HSA-451895 IL2RG binds JAK3 TAS Homo sapiens 8912 R-HSA-9679028 https://reactome.org/PathwayBrowser/#/R-HSA-9679028 JAK3 binds JAK3 inhibitors TAS Homo sapiens 8912 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens 8912 R-MMU-451895 https://reactome.org/PathwayBrowser/#/R-MMU-451895 IL2RG binds JAK3 IEA Mus musculus 8912 R-MMU-9679028 https://reactome.org/PathwayBrowser/#/R-MMU-9679028 JAK3 binds JAK3 inhibitors IEA Mus musculus 8912 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus 8912 R-RNO-9679028 https://reactome.org/PathwayBrowser/#/R-RNO-9679028 JAK3 binds JAK3 inhibitors IEA Rattus norvegicus 8912 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus 8912 R-SSC-451895 https://reactome.org/PathwayBrowser/#/R-SSC-451895 IL2RG binds JAK3 IEA Sus scrofa 8912 R-SSC-9679028 https://reactome.org/PathwayBrowser/#/R-SSC-9679028 JAK3 binds JAK3 inhibitors IEA Sus scrofa 8912 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa 8912 R-XTR-9679028 https://reactome.org/PathwayBrowser/#/R-XTR-9679028 JAK3 binds JAK3 inhibitors IEA Xenopus tropicalis 8913 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 8913 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 8913 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 8913 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 8913 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 8913 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 8913 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 8913 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 8913 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 8913 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 8913 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 8913 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 8913 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 8913 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 8913 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 8913 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 8913 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 8913 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 8924 R-BTA-9692867 https://reactome.org/PathwayBrowser/#/R-BTA-9692867 HRH3 binds pitosilant IEA Bos taurus 8924 R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 8924 R-CEL-9692867 https://reactome.org/PathwayBrowser/#/R-CEL-9692867 HRH3 binds pitosilant IEA Caenorhabditis elegans 8924 R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 8924 R-CFA-9692867 https://reactome.org/PathwayBrowser/#/R-CFA-9692867 HRH3 binds pitosilant IEA Canis familiaris 8924 R-DME-9692867 https://reactome.org/PathwayBrowser/#/R-DME-9692867 HRH3 binds pitosilant IEA Drosophila melanogaster 8924 R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 8924 R-GGA-9692867 https://reactome.org/PathwayBrowser/#/R-GGA-9692867 HRH3 binds pitosilant IEA Gallus gallus 8924 R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 8924 R-HSA-9692867 https://reactome.org/PathwayBrowser/#/R-HSA-9692867 HRH3 binds pitosilant TAS Homo sapiens 8924 R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 8924 R-MMU-9692867 https://reactome.org/PathwayBrowser/#/R-MMU-9692867 HRH3 binds pitosilant IEA Mus musculus 8924 R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 8924 R-RNO-9692867 https://reactome.org/PathwayBrowser/#/R-RNO-9692867 HRH3 binds pitosilant IEA Rattus norvegicus 8924 R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 8924 R-SSC-9692867 https://reactome.org/PathwayBrowser/#/R-SSC-9692867 HRH3 binds pitosilant IEA Sus scrofa 8924 R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 8943 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 8943 R-BTA-9653108 https://reactome.org/PathwayBrowser/#/R-BTA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Bos taurus 8943 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 8943 R-CEL-9653108 https://reactome.org/PathwayBrowser/#/R-CEL-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Caenorhabditis elegans 8943 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 8943 R-CFA-9653108 https://reactome.org/PathwayBrowser/#/R-CFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Canis familiaris 8943 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 8943 R-DME-9653108 https://reactome.org/PathwayBrowser/#/R-DME-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Drosophila melanogaster 8943 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 8943 R-GGA-9653108 https://reactome.org/PathwayBrowser/#/R-GGA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Gallus gallus 8943 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 8943 R-HSA-9653108 https://reactome.org/PathwayBrowser/#/R-HSA-9653108 Raf dimer inhibitors bind RAF heterodimers TAS Homo sapiens 8943 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 8943 R-MMU-9653108 https://reactome.org/PathwayBrowser/#/R-MMU-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Mus musculus 8943 R-PFA-9653108 https://reactome.org/PathwayBrowser/#/R-PFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Plasmodium falciparum 8943 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 8943 R-RNO-9653108 https://reactome.org/PathwayBrowser/#/R-RNO-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Rattus norvegicus 8943 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 8943 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa 8955 R-HSA-9729283 https://reactome.org/PathwayBrowser/#/R-HSA-9729283 Nucleoprotein is methylated by PRMT1 TAS Homo sapiens 8955 R-HSA-9766608 https://reactome.org/PathwayBrowser/#/R-HSA-9766608 PRMT1 binds type I PRMT inhibitors TAS Homo sapiens 8958 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 8966 R-BTA-6800298 https://reactome.org/PathwayBrowser/#/R-BTA-6800298 HGF dimer binds MET IEA Bos taurus 8966 R-BTA-9734070 https://reactome.org/PathwayBrowser/#/R-BTA-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Bos taurus 8966 R-CEL-6800298 https://reactome.org/PathwayBrowser/#/R-CEL-6800298 HGF dimer binds MET IEA Caenorhabditis elegans 8966 R-CEL-9734070 https://reactome.org/PathwayBrowser/#/R-CEL-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Caenorhabditis elegans 8966 R-CFA-6800298 https://reactome.org/PathwayBrowser/#/R-CFA-6800298 HGF dimer binds MET IEA Canis familiaris 8966 R-CFA-9734070 https://reactome.org/PathwayBrowser/#/R-CFA-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Canis familiaris 8966 R-DRE-9734070 https://reactome.org/PathwayBrowser/#/R-DRE-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Danio rerio 8966 R-GGA-6800298 https://reactome.org/PathwayBrowser/#/R-GGA-6800298 HGF dimer binds MET IEA Gallus gallus 8966 R-GGA-9734070 https://reactome.org/PathwayBrowser/#/R-GGA-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Gallus gallus 8966 R-HSA-6800298 https://reactome.org/PathwayBrowser/#/R-HSA-6800298 HGF dimer binds MET TAS Homo sapiens 8966 R-HSA-9734070 https://reactome.org/PathwayBrowser/#/R-HSA-9734070 Anti-MET recombinant therapeutic antibodies bind MET TAS Homo sapiens 8966 R-MMU-6800298 https://reactome.org/PathwayBrowser/#/R-MMU-6800298 HGF dimer binds MET IEA Mus musculus 8966 R-MMU-9734070 https://reactome.org/PathwayBrowser/#/R-MMU-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Mus musculus 8966 R-RNO-6800298 https://reactome.org/PathwayBrowser/#/R-RNO-6800298 HGF dimer binds MET IEA Rattus norvegicus 8966 R-RNO-9734070 https://reactome.org/PathwayBrowser/#/R-RNO-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Rattus norvegicus 8966 R-SSC-6800298 https://reactome.org/PathwayBrowser/#/R-SSC-6800298 HGF dimer binds MET IEA Sus scrofa 8966 R-SSC-9734070 https://reactome.org/PathwayBrowser/#/R-SSC-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Sus scrofa 8966 R-XTR-6800298 https://reactome.org/PathwayBrowser/#/R-XTR-6800298 HGF dimer binds MET IEA Xenopus tropicalis 8966 R-XTR-9734070 https://reactome.org/PathwayBrowser/#/R-XTR-9734070 Anti-MET recombinant therapeutic antibodies bind MET IEA Xenopus tropicalis 8967 R-BTA-9702354 https://reactome.org/PathwayBrowser/#/R-BTA-9702354 CALCA(83-119) binds CALCA antibodies IEA Bos taurus 8967 R-CFA-9702354 https://reactome.org/PathwayBrowser/#/R-CFA-9702354 CALCA(83-119) binds CALCA antibodies IEA Canis familiaris 8967 R-DRE-9702354 https://reactome.org/PathwayBrowser/#/R-DRE-9702354 CALCA(83-119) binds CALCA antibodies IEA Danio rerio 8967 R-GGA-9702354 https://reactome.org/PathwayBrowser/#/R-GGA-9702354 CALCA(83-119) binds CALCA antibodies IEA Gallus gallus 8967 R-HSA-9702354 https://reactome.org/PathwayBrowser/#/R-HSA-9702354 CALCA(83-119) binds CALCA antibodies TAS Homo sapiens 8967 R-MMU-9702354 https://reactome.org/PathwayBrowser/#/R-MMU-9702354 CALCA(83-119) binds CALCA antibodies IEA Mus musculus 8967 R-RNO-9702354 https://reactome.org/PathwayBrowser/#/R-RNO-9702354 CALCA(83-119) binds CALCA antibodies IEA Rattus norvegicus 8967 R-SSC-9702354 https://reactome.org/PathwayBrowser/#/R-SSC-9702354 CALCA(83-119) binds CALCA antibodies IEA Sus scrofa 8967 R-XTR-9702354 https://reactome.org/PathwayBrowser/#/R-XTR-9702354 CALCA(83-119) binds CALCA antibodies IEA Xenopus tropicalis 8988 R-BTA-379387 https://reactome.org/PathwayBrowser/#/R-BTA-379387 COMT transfers Met to DA to form 3MT IEA Bos taurus 8988 R-BTA-9679775 https://reactome.org/PathwayBrowser/#/R-BTA-9679775 COMT binds COMT Inhibitors IEA Bos taurus 8988 R-CFA-379387 https://reactome.org/PathwayBrowser/#/R-CFA-379387 COMT transfers Met to DA to form 3MT IEA Canis familiaris 8988 R-CFA-9679775 https://reactome.org/PathwayBrowser/#/R-CFA-9679775 COMT binds COMT Inhibitors IEA Canis familiaris 8988 R-DRE-379387 https://reactome.org/PathwayBrowser/#/R-DRE-379387 COMT transfers Met to DA to form 3MT IEA Danio rerio 8988 R-DRE-9679775 https://reactome.org/PathwayBrowser/#/R-DRE-9679775 COMT binds COMT Inhibitors IEA Danio rerio 8988 R-GGA-379387 https://reactome.org/PathwayBrowser/#/R-GGA-379387 COMT transfers Met to DA to form 3MT IEA Gallus gallus 8988 R-GGA-9679775 https://reactome.org/PathwayBrowser/#/R-GGA-9679775 COMT binds COMT Inhibitors IEA Gallus gallus 8988 R-HSA-379387 https://reactome.org/PathwayBrowser/#/R-HSA-379387 COMT transfers Met to DA to form 3MT TAS Homo sapiens 8988 R-HSA-9679775 https://reactome.org/PathwayBrowser/#/R-HSA-9679775 COMT binds COMT Inhibitors TAS Homo sapiens 8988 R-MMU-379387 https://reactome.org/PathwayBrowser/#/R-MMU-379387 COMT transfers Met to DA to form 3MT IEA Mus musculus 8988 R-MMU-9679775 https://reactome.org/PathwayBrowser/#/R-MMU-9679775 COMT binds COMT Inhibitors IEA Mus musculus 8988 R-RNO-379387 https://reactome.org/PathwayBrowser/#/R-RNO-379387 COMT transfers Met to DA to form 3MT IEA Rattus norvegicus 8988 R-RNO-9679775 https://reactome.org/PathwayBrowser/#/R-RNO-9679775 COMT binds COMT Inhibitors IEA Rattus norvegicus 8988 R-SPO-379387 https://reactome.org/PathwayBrowser/#/R-SPO-379387 COMT transfers Met to DA to form 3MT IEA Schizosaccharomyces pombe 8988 R-SPO-9679775 https://reactome.org/PathwayBrowser/#/R-SPO-9679775 COMT binds COMT Inhibitors IEA Schizosaccharomyces pombe 8988 R-SSC-379387 https://reactome.org/PathwayBrowser/#/R-SSC-379387 COMT transfers Met to DA to form 3MT IEA Sus scrofa 8988 R-SSC-9679775 https://reactome.org/PathwayBrowser/#/R-SSC-9679775 COMT binds COMT Inhibitors IEA Sus scrofa 8988 R-XTR-379387 https://reactome.org/PathwayBrowser/#/R-XTR-379387 COMT transfers Met to DA to form 3MT IEA Xenopus tropicalis 8988 R-XTR-9679775 https://reactome.org/PathwayBrowser/#/R-XTR-9679775 COMT binds COMT Inhibitors IEA Xenopus tropicalis 8993 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 8993 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 8993 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 8993 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 8993 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 8993 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 8993 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 8993 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 8993 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 8993 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 8993 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 8993 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 8993 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 8993 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 8993 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 8994 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 8994 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 8994 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 8994 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 8994 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 8994 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 8994 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 8994 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 8994 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 8994 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 8994 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 8994 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 8994 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 8994 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 8994 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 90 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 90 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 90 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 90 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 90 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 90 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 90 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 90 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 90 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 90 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 90 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 90 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 90 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 90 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 90 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 90 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 90 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 90 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 90 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 90 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 9015 R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 9015 R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 9015 R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 9015 R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 9015 R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 9015 R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 9015 R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 9015 R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 9015 R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 9015 R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 9015 R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 9015 R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 9015 R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 9015 R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 9015 R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 9015 R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 9029 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 9029 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 9029 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 9029 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 9029 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 9029 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 9029 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 9029 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 9029 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 9029 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 9029 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 9029 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 9029 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 9029 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 9029 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 9029 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 9029 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 9029 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 9029 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 9029 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 9029 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 9029 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 9042 R-BTA-9703895 https://reactome.org/PathwayBrowser/#/R-BTA-9703895 CASR binds CASR agonists IEA Bos taurus 9042 R-CFA-9703895 https://reactome.org/PathwayBrowser/#/R-CFA-9703895 CASR binds CASR agonists IEA Canis familiaris 9042 R-GGA-9703895 https://reactome.org/PathwayBrowser/#/R-GGA-9703895 CASR binds CASR agonists IEA Gallus gallus 9042 R-HSA-9703895 https://reactome.org/PathwayBrowser/#/R-HSA-9703895 CASR binds CASR agonists TAS Homo sapiens 9042 R-MMU-9703895 https://reactome.org/PathwayBrowser/#/R-MMU-9703895 CASR binds CASR agonists IEA Mus musculus 9042 R-RNO-9703895 https://reactome.org/PathwayBrowser/#/R-RNO-9703895 CASR binds CASR agonists IEA Rattus norvegicus 9042 R-SSC-9703895 https://reactome.org/PathwayBrowser/#/R-SSC-9703895 CASR binds CASR agonists IEA Sus scrofa 9042 R-XTR-9703895 https://reactome.org/PathwayBrowser/#/R-XTR-9703895 CASR binds CASR agonists IEA Xenopus tropicalis 9043 R-BTA-9706837 https://reactome.org/PathwayBrowser/#/R-BTA-9706837 AR binds AR antagonists IEA Bos taurus 9043 R-CFA-9706837 https://reactome.org/PathwayBrowser/#/R-CFA-9706837 AR binds AR antagonists IEA Canis familiaris 9043 R-DME-9706837 https://reactome.org/PathwayBrowser/#/R-DME-9706837 AR binds AR antagonists IEA Drosophila melanogaster 9043 R-DRE-9706837 https://reactome.org/PathwayBrowser/#/R-DRE-9706837 AR binds AR antagonists IEA Danio rerio 9043 R-GGA-9706837 https://reactome.org/PathwayBrowser/#/R-GGA-9706837 AR binds AR antagonists IEA Gallus gallus 9043 R-HSA-9706837 https://reactome.org/PathwayBrowser/#/R-HSA-9706837 AR binds AR antagonists TAS Homo sapiens 9043 R-MMU-9706837 https://reactome.org/PathwayBrowser/#/R-MMU-9706837 AR binds AR antagonists IEA Mus musculus 9043 R-PFA-9706837 https://reactome.org/PathwayBrowser/#/R-PFA-9706837 AR binds AR antagonists IEA Plasmodium falciparum 9043 R-RNO-9706837 https://reactome.org/PathwayBrowser/#/R-RNO-9706837 AR binds AR antagonists IEA Rattus norvegicus 9043 R-SSC-9706837 https://reactome.org/PathwayBrowser/#/R-SSC-9706837 AR binds AR antagonists IEA Sus scrofa 9043 R-XTR-9706837 https://reactome.org/PathwayBrowser/#/R-XTR-9706837 AR binds AR antagonists IEA Xenopus tropicalis 9052 R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 9052 R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 9052 R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 9052 R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 9052 R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 9052 R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 9052 R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 9052 R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 9052 R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 9052 R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 9052 R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 9052 R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 9063 R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 9063 R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 9063 R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 9063 R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 9063 R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 9063 R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 9063 R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 9063 R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 9063 R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 9063 R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 9071 R-BTA-9696323 https://reactome.org/PathwayBrowser/#/R-BTA-9696323 CNRs bind CNR agonists IEA Bos taurus 9071 R-CFA-9696323 https://reactome.org/PathwayBrowser/#/R-CFA-9696323 CNRs bind CNR agonists IEA Canis familiaris 9071 R-DRE-9696323 https://reactome.org/PathwayBrowser/#/R-DRE-9696323 CNRs bind CNR agonists IEA Danio rerio 9071 R-GGA-9696323 https://reactome.org/PathwayBrowser/#/R-GGA-9696323 CNRs bind CNR agonists IEA Gallus gallus 9071 R-HSA-9696323 https://reactome.org/PathwayBrowser/#/R-HSA-9696323 CNRs bind CNR agonists TAS Homo sapiens 9071 R-MMU-9696323 https://reactome.org/PathwayBrowser/#/R-MMU-9696323 CNRs bind CNR agonists IEA Mus musculus 9071 R-RNO-9696323 https://reactome.org/PathwayBrowser/#/R-RNO-9696323 CNRs bind CNR agonists IEA Rattus norvegicus 9071 R-SSC-9696323 https://reactome.org/PathwayBrowser/#/R-SSC-9696323 CNRs bind CNR agonists IEA Sus scrofa 9071 R-XTR-9696323 https://reactome.org/PathwayBrowser/#/R-XTR-9696323 CNRs bind CNR agonists IEA Xenopus tropicalis 9072 R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 9072 R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 9072 R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 9072 R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 9072 R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 9073 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 9073 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 9073 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 9073 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 9073 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 9073 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 9073 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 9073 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 9073 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 9073 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 9073 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 9073 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 9073 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 9073 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 9073 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 9074 R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 9074 R-CEL-9634834 https://reactome.org/PathwayBrowser/#/R-CEL-9634834 ACHEIs bind ACHE IEA Caenorhabditis elegans 9074 R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 9074 R-DDI-9634834 https://reactome.org/PathwayBrowser/#/R-DDI-9634834 ACHEIs bind ACHE IEA Dictyostelium discoideum 9074 R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 9074 R-DME-9634834 https://reactome.org/PathwayBrowser/#/R-DME-9634834 ACHEIs bind ACHE IEA Drosophila melanogaster 9074 R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 9074 R-DRE-9634834 https://reactome.org/PathwayBrowser/#/R-DRE-9634834 ACHEIs bind ACHE IEA Danio rerio 9074 R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 9074 R-GGA-9634834 https://reactome.org/PathwayBrowser/#/R-GGA-9634834 ACHEIs bind ACHE IEA Gallus gallus 9074 R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 9074 R-HSA-9634834 https://reactome.org/PathwayBrowser/#/R-HSA-9634834 ACHEIs bind ACHE TAS Homo sapiens 9074 R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 9074 R-SSC-9634834 https://reactome.org/PathwayBrowser/#/R-SSC-9634834 ACHEIs bind ACHE IEA Sus scrofa 9074 R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 9075 R-HSA-9730736 https://reactome.org/PathwayBrowser/#/R-HSA-9730736 Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA IEA Homo sapiens 9075 R-HSA-9730767 https://reactome.org/PathwayBrowser/#/R-HSA-9730767 Monofunctional chemotherapeutic alkylating drugs produce 7-methylguanine in dsDNA IEA Homo sapiens 9075 R-HSA-9732692 https://reactome.org/PathwayBrowser/#/R-HSA-9732692 Triazenes produce DNA damage in the form of O6-methylguanine IEA Homo sapiens 9093 R-BTA-1067667 https://reactome.org/PathwayBrowser/#/R-BTA-1067667 IL6 binds IL6R IEA Bos taurus 9093 R-BTA-9681294 https://reactome.org/PathwayBrowser/#/R-BTA-9681294 IL6R binds IL6R inhibitors IEA Bos taurus 9093 R-CEL-9681294 https://reactome.org/PathwayBrowser/#/R-CEL-9681294 IL6R binds IL6R inhibitors IEA Caenorhabditis elegans 9093 R-CFA-1067667 https://reactome.org/PathwayBrowser/#/R-CFA-1067667 IL6 binds IL6R IEA Canis familiaris 9093 R-CFA-9681294 https://reactome.org/PathwayBrowser/#/R-CFA-9681294 IL6R binds IL6R inhibitors IEA Canis familiaris 9093 R-DRE-1067667 https://reactome.org/PathwayBrowser/#/R-DRE-1067667 IL6 binds IL6R IEA Danio rerio 9093 R-DRE-9681294 https://reactome.org/PathwayBrowser/#/R-DRE-9681294 IL6R binds IL6R inhibitors IEA Danio rerio 9093 R-GGA-1067667 https://reactome.org/PathwayBrowser/#/R-GGA-1067667 IL6 binds IL6R IEA Gallus gallus 9093 R-GGA-9681294 https://reactome.org/PathwayBrowser/#/R-GGA-9681294 IL6R binds IL6R inhibitors IEA Gallus gallus 9093 R-HSA-1067667 https://reactome.org/PathwayBrowser/#/R-HSA-1067667 IL6 binds IL6R TAS Homo sapiens 9093 R-HSA-9681294 https://reactome.org/PathwayBrowser/#/R-HSA-9681294 IL6R binds IL6R inhibitors TAS Homo sapiens 9093 R-MMU-1067667 https://reactome.org/PathwayBrowser/#/R-MMU-1067667 IL6 binds IL6R IEA Mus musculus 9093 R-MMU-9681294 https://reactome.org/PathwayBrowser/#/R-MMU-9681294 IL6R binds IL6R inhibitors IEA Mus musculus 9093 R-RNO-1067667 https://reactome.org/PathwayBrowser/#/R-RNO-1067667 IL6 binds IL6R IEA Rattus norvegicus 9093 R-RNO-9681294 https://reactome.org/PathwayBrowser/#/R-RNO-9681294 IL6R binds IL6R inhibitors IEA Rattus norvegicus 91 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 91 R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 91 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 91 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 91 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 91 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 91 R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 91 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 91 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 91 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 91 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 91 R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 91 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 91 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 91 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 91 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 91 R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 91 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 91 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 91 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 91 R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 91 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 91 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 91 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 91 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 91 R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 91 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 91 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 91 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 91 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 91 R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 91 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 91 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 91 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 91 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 91 R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 91 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 91 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 91 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 91 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 91 R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 91 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 91 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 91 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 91 R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 91 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 91 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 9123 R-BTA-9823065 https://reactome.org/PathwayBrowser/#/R-BTA-9823065 GPIb:IX:V binds to VWF multimer:collagen IEA Bos taurus 9123 R-DRE-9823065 https://reactome.org/PathwayBrowser/#/R-DRE-9823065 GPIb:IX:V binds to VWF multimer:collagen IEA Danio rerio 9123 R-GGA-9823065 https://reactome.org/PathwayBrowser/#/R-GGA-9823065 GPIb:IX:V binds to VWF multimer:collagen IEA Gallus gallus 9123 R-HSA-9822734 https://reactome.org/PathwayBrowser/#/R-HSA-9822734 Caplacizumab binds VWF TAS Homo sapiens 9123 R-HSA-9823065 https://reactome.org/PathwayBrowser/#/R-HSA-9823065 GPIb:IX:V binds to VWF multimer:collagen TAS Homo sapiens 9123 R-HSA-9844251 https://reactome.org/PathwayBrowser/#/R-HSA-9844251 GP1BA variant binds to VWF multimer:collagen TAS Homo sapiens 9123 R-MMU-9823065 https://reactome.org/PathwayBrowser/#/R-MMU-9823065 GPIb:IX:V binds to VWF multimer:collagen IEA Mus musculus 9123 R-SSC-9823065 https://reactome.org/PathwayBrowser/#/R-SSC-9823065 GPIb:IX:V binds to VWF multimer:collagen IEA Sus scrofa 9123 R-XTR-9823065 https://reactome.org/PathwayBrowser/#/R-XTR-9823065 GPIb:IX:V binds to VWF multimer:collagen IEA Xenopus tropicalis 9132 R-BTA-9679477 https://reactome.org/PathwayBrowser/#/R-BTA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Bos taurus 9132 R-BTA-9691215 https://reactome.org/PathwayBrowser/#/R-BTA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Bos taurus 9132 R-CFA-9679477 https://reactome.org/PathwayBrowser/#/R-CFA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Canis familiaris 9132 R-CFA-9691215 https://reactome.org/PathwayBrowser/#/R-CFA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Canis familiaris 9132 R-DRE-9679477 https://reactome.org/PathwayBrowser/#/R-DRE-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Danio rerio 9132 R-DRE-9691215 https://reactome.org/PathwayBrowser/#/R-DRE-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Danio rerio 9132 R-GGA-9679477 https://reactome.org/PathwayBrowser/#/R-GGA-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Gallus gallus 9132 R-GGA-9691215 https://reactome.org/PathwayBrowser/#/R-GGA-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Gallus gallus 9132 R-HSA-9679477 https://reactome.org/PathwayBrowser/#/R-HSA-9679477 VEGFA-165 dimer binds VEGFA inhibitors TAS Homo sapiens 9132 R-HSA-9691215 https://reactome.org/PathwayBrowser/#/R-HSA-9691215 VEGFA-165 dimer binds VEGFR2 dimer TAS Homo sapiens 9132 R-MMU-9679477 https://reactome.org/PathwayBrowser/#/R-MMU-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Mus musculus 9132 R-MMU-9691215 https://reactome.org/PathwayBrowser/#/R-MMU-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Mus musculus 9132 R-RNO-9679477 https://reactome.org/PathwayBrowser/#/R-RNO-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Rattus norvegicus 9132 R-RNO-9691215 https://reactome.org/PathwayBrowser/#/R-RNO-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Rattus norvegicus 9132 R-SSC-9679477 https://reactome.org/PathwayBrowser/#/R-SSC-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Sus scrofa 9132 R-SSC-9691215 https://reactome.org/PathwayBrowser/#/R-SSC-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Sus scrofa 9132 R-XTR-9679477 https://reactome.org/PathwayBrowser/#/R-XTR-9679477 VEGFA-165 dimer binds VEGFA inhibitors IEA Xenopus tropicalis 9132 R-XTR-9691215 https://reactome.org/PathwayBrowser/#/R-XTR-9691215 VEGFA-165 dimer binds VEGFR2 dimer IEA Xenopus tropicalis 9133 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 9133 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 9133 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 9133 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 9133 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 9133 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 9133 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 9133 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 9133 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 9133 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 9133 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 9133 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 9133 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 9133 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 9133 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 9133 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 9133 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 9133 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 9151 R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 9151 R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 9151 R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 9151 R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 9151 R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 9151 R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 9151 R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 9151 R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 9151 R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 9151 R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 9151 R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 9172 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 9172 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 9172 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 9172 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 9172 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 9172 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 9172 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 9172 R-HSA-9674015 https://reactome.org/PathwayBrowser/#/R-HSA-9674015 Olaratumab binds PDGFRA TAS Homo sapiens 9172 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 9172 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 9172 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 9172 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 9175 R-BTA-186773 https://reactome.org/PathwayBrowser/#/R-BTA-186773 PDGF dimer binds two receptors simultaneously IEA Bos taurus 9175 R-BTA-205289 https://reactome.org/PathwayBrowser/#/R-BTA-205289 Autophosphorylation of KIT IEA Bos taurus 9175 R-BTA-9674095 https://reactome.org/PathwayBrowser/#/R-BTA-9674095 PDGFRs bind type II TKI IEA Bos taurus 9175 R-BTA-9681375 https://reactome.org/PathwayBrowser/#/R-BTA-9681375 KIT binds ripretinib IEA Bos taurus 9175 R-CEL-186773 https://reactome.org/PathwayBrowser/#/R-CEL-186773 PDGF dimer binds two receptors simultaneously IEA Caenorhabditis elegans 9175 R-CEL-9674095 https://reactome.org/PathwayBrowser/#/R-CEL-9674095 PDGFRs bind type II TKI IEA Caenorhabditis elegans 9175 R-CEL-9681375 https://reactome.org/PathwayBrowser/#/R-CEL-9681375 KIT binds ripretinib IEA Caenorhabditis elegans 9175 R-CFA-186773 https://reactome.org/PathwayBrowser/#/R-CFA-186773 PDGF dimer binds two receptors simultaneously IEA Canis familiaris 9175 R-CFA-205289 https://reactome.org/PathwayBrowser/#/R-CFA-205289 Autophosphorylation of KIT IEA Canis familiaris 9175 R-CFA-9674095 https://reactome.org/PathwayBrowser/#/R-CFA-9674095 PDGFRs bind type II TKI IEA Canis familiaris 9175 R-CFA-9681375 https://reactome.org/PathwayBrowser/#/R-CFA-9681375 KIT binds ripretinib IEA Canis familiaris 9175 R-DME-186773 https://reactome.org/PathwayBrowser/#/R-DME-186773 PDGF dimer binds two receptors simultaneously IEA Drosophila melanogaster 9175 R-DME-9674095 https://reactome.org/PathwayBrowser/#/R-DME-9674095 PDGFRs bind type II TKI IEA Drosophila melanogaster 9175 R-DME-9681375 https://reactome.org/PathwayBrowser/#/R-DME-9681375 KIT binds ripretinib IEA Drosophila melanogaster 9175 R-DRE-186773 https://reactome.org/PathwayBrowser/#/R-DRE-186773 PDGF dimer binds two receptors simultaneously IEA Danio rerio 9175 R-DRE-205289 https://reactome.org/PathwayBrowser/#/R-DRE-205289 Autophosphorylation of KIT IEA Danio rerio 9175 R-DRE-9674095 https://reactome.org/PathwayBrowser/#/R-DRE-9674095 PDGFRs bind type II TKI IEA Danio rerio 9175 R-DRE-9681375 https://reactome.org/PathwayBrowser/#/R-DRE-9681375 KIT binds ripretinib IEA Danio rerio 9175 R-GGA-186773 https://reactome.org/PathwayBrowser/#/R-GGA-186773 PDGF dimer binds two receptors simultaneously IEA Gallus gallus 9175 R-GGA-205289 https://reactome.org/PathwayBrowser/#/R-GGA-205289 Autophosphorylation of KIT IEA Gallus gallus 9175 R-GGA-9674095 https://reactome.org/PathwayBrowser/#/R-GGA-9674095 PDGFRs bind type II TKI IEA Gallus gallus 9175 R-GGA-9681375 https://reactome.org/PathwayBrowser/#/R-GGA-9681375 KIT binds ripretinib IEA Gallus gallus 9175 R-HSA-186773 https://reactome.org/PathwayBrowser/#/R-HSA-186773 PDGF dimer binds two receptors simultaneously TAS Homo sapiens 9175 R-HSA-205289 https://reactome.org/PathwayBrowser/#/R-HSA-205289 Autophosphorylation of KIT TAS Homo sapiens 9175 R-HSA-9674095 https://reactome.org/PathwayBrowser/#/R-HSA-9674095 PDGFRs bind type II TKI TAS Homo sapiens 9175 R-HSA-9674430 https://reactome.org/PathwayBrowser/#/R-HSA-9674430 PDGFR mutants bind type II TKIs TAS Homo sapiens 9175 R-HSA-9681375 https://reactome.org/PathwayBrowser/#/R-HSA-9681375 KIT binds ripretinib TAS Homo sapiens 9175 R-HSA-9681382 https://reactome.org/PathwayBrowser/#/R-HSA-9681382 KIT mutants bind ripretinib TAS Homo sapiens 9175 R-MMU-186773 https://reactome.org/PathwayBrowser/#/R-MMU-186773 PDGF dimer binds two receptors simultaneously IEA Mus musculus 9175 R-MMU-205289 https://reactome.org/PathwayBrowser/#/R-MMU-205289 Autophosphorylation of KIT IEA Mus musculus 9175 R-MMU-9674095 https://reactome.org/PathwayBrowser/#/R-MMU-9674095 PDGFRs bind type II TKI IEA Mus musculus 9175 R-MMU-9681375 https://reactome.org/PathwayBrowser/#/R-MMU-9681375 KIT binds ripretinib IEA Mus musculus 9175 R-RNO-186773 https://reactome.org/PathwayBrowser/#/R-RNO-186773 PDGF dimer binds two receptors simultaneously IEA Rattus norvegicus 9175 R-RNO-205289 https://reactome.org/PathwayBrowser/#/R-RNO-205289 Autophosphorylation of KIT IEA Rattus norvegicus 9175 R-RNO-9674095 https://reactome.org/PathwayBrowser/#/R-RNO-9674095 PDGFRs bind type II TKI IEA Rattus norvegicus 9175 R-RNO-9681375 https://reactome.org/PathwayBrowser/#/R-RNO-9681375 KIT binds ripretinib IEA Rattus norvegicus 9175 R-SSC-186773 https://reactome.org/PathwayBrowser/#/R-SSC-186773 PDGF dimer binds two receptors simultaneously IEA Sus scrofa 9175 R-SSC-205289 https://reactome.org/PathwayBrowser/#/R-SSC-205289 Autophosphorylation of KIT IEA Sus scrofa 9175 R-SSC-9674095 https://reactome.org/PathwayBrowser/#/R-SSC-9674095 PDGFRs bind type II TKI IEA Sus scrofa 9175 R-SSC-9681375 https://reactome.org/PathwayBrowser/#/R-SSC-9681375 KIT binds ripretinib IEA Sus scrofa 9175 R-XTR-186773 https://reactome.org/PathwayBrowser/#/R-XTR-186773 PDGF dimer binds two receptors simultaneously IEA Xenopus tropicalis 9175 R-XTR-205289 https://reactome.org/PathwayBrowser/#/R-XTR-205289 Autophosphorylation of KIT IEA Xenopus tropicalis 9175 R-XTR-9674095 https://reactome.org/PathwayBrowser/#/R-XTR-9674095 PDGFRs bind type II TKI IEA Xenopus tropicalis 9175 R-XTR-9681375 https://reactome.org/PathwayBrowser/#/R-XTR-9681375 KIT binds ripretinib IEA Xenopus tropicalis 9176 R-HSA-1220611 https://reactome.org/PathwayBrowser/#/R-HSA-1220611 Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors TAS Homo sapiens 9176 R-HSA-1225978 https://reactome.org/PathwayBrowser/#/R-HSA-1225978 Covalent tyrosine kinase inhibitors bind and inhibit wild-type EGF:EGFR dimers TAS Homo sapiens 9184 R-HSA-9685655 https://reactome.org/PathwayBrowser/#/R-HSA-9685655 CTSL bind CTSL inhibitors TAS Homo sapiens 9184 R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 9184 R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 9208 R-BTA-9702354 https://reactome.org/PathwayBrowser/#/R-BTA-9702354 CALCA(83-119) binds CALCA antibodies IEA Bos taurus 9208 R-CFA-9702354 https://reactome.org/PathwayBrowser/#/R-CFA-9702354 CALCA(83-119) binds CALCA antibodies IEA Canis familiaris 9208 R-DRE-9702354 https://reactome.org/PathwayBrowser/#/R-DRE-9702354 CALCA(83-119) binds CALCA antibodies IEA Danio rerio 9208 R-GGA-9702354 https://reactome.org/PathwayBrowser/#/R-GGA-9702354 CALCA(83-119) binds CALCA antibodies IEA Gallus gallus 9208 R-HSA-9702354 https://reactome.org/PathwayBrowser/#/R-HSA-9702354 CALCA(83-119) binds CALCA antibodies TAS Homo sapiens 9208 R-MMU-9702354 https://reactome.org/PathwayBrowser/#/R-MMU-9702354 CALCA(83-119) binds CALCA antibodies IEA Mus musculus 9208 R-RNO-9702354 https://reactome.org/PathwayBrowser/#/R-RNO-9702354 CALCA(83-119) binds CALCA antibodies IEA Rattus norvegicus 9208 R-SSC-9702354 https://reactome.org/PathwayBrowser/#/R-SSC-9702354 CALCA(83-119) binds CALCA antibodies IEA Sus scrofa 9208 R-XTR-9702354 https://reactome.org/PathwayBrowser/#/R-XTR-9702354 CALCA(83-119) binds CALCA antibodies IEA Xenopus tropicalis 9210 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 9210 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 9210 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 9210 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 9210 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 9210 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 9210 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 9210 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 9210 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 9214 R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 9215 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 9215 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 9215 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 9215 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 9215 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 9215 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 9215 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 9215 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 9215 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 9215 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 9218 R-BTA-9957021 https://reactome.org/PathwayBrowser/#/R-BTA-9957021 C3 binds C3 inhibitors IEA Bos taurus 9218 R-CFA-9957021 https://reactome.org/PathwayBrowser/#/R-CFA-9957021 C3 binds C3 inhibitors IEA Canis familiaris 9218 R-DRE-9957021 https://reactome.org/PathwayBrowser/#/R-DRE-9957021 C3 binds C3 inhibitors IEA Danio rerio 9218 R-GGA-9957021 https://reactome.org/PathwayBrowser/#/R-GGA-9957021 C3 binds C3 inhibitors IEA Gallus gallus 9218 R-HSA-9957021 https://reactome.org/PathwayBrowser/#/R-HSA-9957021 C3 binds C3 inhibitors TAS Homo sapiens 9218 R-MMU-9957021 https://reactome.org/PathwayBrowser/#/R-MMU-9957021 C3 binds C3 inhibitors IEA Mus musculus 9218 R-RNO-9957021 https://reactome.org/PathwayBrowser/#/R-RNO-9957021 C3 binds C3 inhibitors IEA Rattus norvegicus 9218 R-SSC-9957021 https://reactome.org/PathwayBrowser/#/R-SSC-9957021 C3 binds C3 inhibitors IEA Sus scrofa 9218 R-XTR-9957021 https://reactome.org/PathwayBrowser/#/R-XTR-9957021 C3 binds C3 inhibitors IEA Xenopus tropicalis 9229 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 9229 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 9229 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 9229 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 9229 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 9229 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 9229 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 9229 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 9229 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 9250 R-BTA-9702818 https://reactome.org/PathwayBrowser/#/R-BTA-9702818 CALCR binds erenumab IEA Bos taurus 9250 R-CEL-9702818 https://reactome.org/PathwayBrowser/#/R-CEL-9702818 CALCR binds erenumab IEA Caenorhabditis elegans 9250 R-CFA-9702818 https://reactome.org/PathwayBrowser/#/R-CFA-9702818 CALCR binds erenumab IEA Canis familiaris 9250 R-DME-9702818 https://reactome.org/PathwayBrowser/#/R-DME-9702818 CALCR binds erenumab IEA Drosophila melanogaster 9250 R-GGA-9702818 https://reactome.org/PathwayBrowser/#/R-GGA-9702818 CALCR binds erenumab IEA Gallus gallus 9250 R-HSA-9702818 https://reactome.org/PathwayBrowser/#/R-HSA-9702818 CALCR binds erenumab TAS Homo sapiens 9250 R-MMU-9702818 https://reactome.org/PathwayBrowser/#/R-MMU-9702818 CALCR binds erenumab IEA Mus musculus 9250 R-RNO-9702818 https://reactome.org/PathwayBrowser/#/R-RNO-9702818 CALCR binds erenumab IEA Rattus norvegicus 9250 R-SSC-9702818 https://reactome.org/PathwayBrowser/#/R-SSC-9702818 CALCR binds erenumab IEA Sus scrofa 9250 R-XTR-9702818 https://reactome.org/PathwayBrowser/#/R-XTR-9702818 CALCR binds erenumab IEA Xenopus tropicalis 9265 R-BTA-9691421 https://reactome.org/PathwayBrowser/#/R-BTA-9691421 BTK binds BTK inhibitors IEA Bos taurus 9265 R-CFA-9691421 https://reactome.org/PathwayBrowser/#/R-CFA-9691421 BTK binds BTK inhibitors IEA Canis familiaris 9265 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus 9265 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens 9265 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus 9265 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus 9265 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa 9289 R-BTA-9678854 https://reactome.org/PathwayBrowser/#/R-BTA-9678854 S1PR1 binds S1PR1 agonists IEA Bos taurus 9289 R-BTA-9690449 https://reactome.org/PathwayBrowser/#/R-BTA-9690449 S1PR1 bind S1P IEA Bos taurus 9289 R-CFA-9678854 https://reactome.org/PathwayBrowser/#/R-CFA-9678854 S1PR1 binds S1PR1 agonists IEA Canis familiaris 9289 R-CFA-9690449 https://reactome.org/PathwayBrowser/#/R-CFA-9690449 S1PR1 bind S1P IEA Canis familiaris 9289 R-DRE-9678854 https://reactome.org/PathwayBrowser/#/R-DRE-9678854 S1PR1 binds S1PR1 agonists IEA Danio rerio 9289 R-DRE-9690449 https://reactome.org/PathwayBrowser/#/R-DRE-9690449 S1PR1 bind S1P IEA Danio rerio 9289 R-GGA-9678854 https://reactome.org/PathwayBrowser/#/R-GGA-9678854 S1PR1 binds S1PR1 agonists IEA Gallus gallus 9289 R-GGA-9690449 https://reactome.org/PathwayBrowser/#/R-GGA-9690449 S1PR1 bind S1P IEA Gallus gallus 9289 R-HSA-9678854 https://reactome.org/PathwayBrowser/#/R-HSA-9678854 S1PR1 binds S1PR1 agonists TAS Homo sapiens 9289 R-HSA-9690449 https://reactome.org/PathwayBrowser/#/R-HSA-9690449 S1PR1 bind S1P TAS Homo sapiens 9289 R-MMU-9678854 https://reactome.org/PathwayBrowser/#/R-MMU-9678854 S1PR1 binds S1PR1 agonists IEA Mus musculus 9289 R-MMU-9690449 https://reactome.org/PathwayBrowser/#/R-MMU-9690449 S1PR1 bind S1P IEA Mus musculus 9289 R-RNO-9678854 https://reactome.org/PathwayBrowser/#/R-RNO-9678854 S1PR1 binds S1PR1 agonists IEA Rattus norvegicus 9289 R-RNO-9690449 https://reactome.org/PathwayBrowser/#/R-RNO-9690449 S1PR1 bind S1P IEA Rattus norvegicus 9289 R-SSC-9678854 https://reactome.org/PathwayBrowser/#/R-SSC-9678854 S1PR1 binds S1PR1 agonists IEA Sus scrofa 9289 R-SSC-9690449 https://reactome.org/PathwayBrowser/#/R-SSC-9690449 S1PR1 bind S1P IEA Sus scrofa 9289 R-XTR-9678854 https://reactome.org/PathwayBrowser/#/R-XTR-9678854 S1PR1 binds S1PR1 agonists IEA Xenopus tropicalis 9289 R-XTR-9690449 https://reactome.org/PathwayBrowser/#/R-XTR-9690449 S1PR1 bind S1P IEA Xenopus tropicalis 9295 R-BTA-9689680 https://reactome.org/PathwayBrowser/#/R-BTA-9689680 IFNG dimer binds IFNG inhibitors IEA Bos taurus 9295 R-CFA-9689680 https://reactome.org/PathwayBrowser/#/R-CFA-9689680 IFNG dimer binds IFNG inhibitors IEA Canis familiaris 9295 R-DRE-9689680 https://reactome.org/PathwayBrowser/#/R-DRE-9689680 IFNG dimer binds IFNG inhibitors IEA Danio rerio 9295 R-GGA-9689680 https://reactome.org/PathwayBrowser/#/R-GGA-9689680 IFNG dimer binds IFNG inhibitors IEA Gallus gallus 9295 R-HSA-9689680 https://reactome.org/PathwayBrowser/#/R-HSA-9689680 IFNG dimer binds IFNG inhibitors TAS Homo sapiens 9295 R-MMU-9689680 https://reactome.org/PathwayBrowser/#/R-MMU-9689680 IFNG dimer binds IFNG inhibitors IEA Mus musculus 9295 R-RNO-9689680 https://reactome.org/PathwayBrowser/#/R-RNO-9689680 IFNG dimer binds IFNG inhibitors IEA Rattus norvegicus 9295 R-SSC-9689680 https://reactome.org/PathwayBrowser/#/R-SSC-9689680 IFNG dimer binds IFNG inhibitors IEA Sus scrofa 93 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 93 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 93 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 93 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 93 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 93 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 93 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 93 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 93 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 93 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 9322 R-BTA-419049 https://reactome.org/PathwayBrowser/#/R-BTA-419049 ROCK activation by RHO IEA Bos taurus 9322 R-BTA-9680443 https://reactome.org/PathwayBrowser/#/R-BTA-9680443 ROCK1,2 bind ROCKi IEA Bos taurus 9322 R-CEL-419049 https://reactome.org/PathwayBrowser/#/R-CEL-419049 ROCK activation by RHO IEA Caenorhabditis elegans 9322 R-CEL-9680443 https://reactome.org/PathwayBrowser/#/R-CEL-9680443 ROCK1,2 bind ROCKi IEA Caenorhabditis elegans 9322 R-CFA-419049 https://reactome.org/PathwayBrowser/#/R-CFA-419049 ROCK activation by RHO IEA Canis familiaris 9322 R-CFA-9680443 https://reactome.org/PathwayBrowser/#/R-CFA-9680443 ROCK1,2 bind ROCKi IEA Canis familiaris 9322 R-DME-419049 https://reactome.org/PathwayBrowser/#/R-DME-419049 ROCK activation by RHO IEA Drosophila melanogaster 9322 R-DME-9680443 https://reactome.org/PathwayBrowser/#/R-DME-9680443 ROCK1,2 bind ROCKi IEA Drosophila melanogaster 9322 R-DRE-419049 https://reactome.org/PathwayBrowser/#/R-DRE-419049 ROCK activation by RHO IEA Danio rerio 9322 R-DRE-9680443 https://reactome.org/PathwayBrowser/#/R-DRE-9680443 ROCK1,2 bind ROCKi IEA Danio rerio 9322 R-GGA-419049 https://reactome.org/PathwayBrowser/#/R-GGA-419049 ROCK activation by RHO IEA Gallus gallus 9322 R-GGA-9680443 https://reactome.org/PathwayBrowser/#/R-GGA-9680443 ROCK1,2 bind ROCKi IEA Gallus gallus 9322 R-HSA-419049 https://reactome.org/PathwayBrowser/#/R-HSA-419049 ROCK activation by RHO TAS Homo sapiens 9322 R-HSA-9680443 https://reactome.org/PathwayBrowser/#/R-HSA-9680443 ROCK1,2 bind ROCKi TAS Homo sapiens 9322 R-MMU-419049 https://reactome.org/PathwayBrowser/#/R-MMU-419049 ROCK activation by RHO IEA Mus musculus 9322 R-MMU-9680443 https://reactome.org/PathwayBrowser/#/R-MMU-9680443 ROCK1,2 bind ROCKi IEA Mus musculus 9322 R-RNO-419049 https://reactome.org/PathwayBrowser/#/R-RNO-419049 ROCK activation by RHO IEA Rattus norvegicus 9322 R-RNO-9680443 https://reactome.org/PathwayBrowser/#/R-RNO-9680443 ROCK1,2 bind ROCKi IEA Rattus norvegicus 9322 R-SSC-419049 https://reactome.org/PathwayBrowser/#/R-SSC-419049 ROCK activation by RHO IEA Sus scrofa 9322 R-SSC-9680443 https://reactome.org/PathwayBrowser/#/R-SSC-9680443 ROCK1,2 bind ROCKi IEA Sus scrofa 9322 R-XTR-419049 https://reactome.org/PathwayBrowser/#/R-XTR-419049 ROCK activation by RHO IEA Xenopus tropicalis 9322 R-XTR-9680443 https://reactome.org/PathwayBrowser/#/R-XTR-9680443 ROCK1,2 bind ROCKi IEA Xenopus tropicalis 9326 R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 9326 R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 9326 R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 9326 R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 9326 R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 9326 R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 9326 R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 9326 R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 9326 R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 9326 R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 9326 R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 9326 R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 9326 R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 9326 R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 9326 R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 9326 R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 9326 R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 9326 R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 9326 R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 9326 R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 9326 R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 9326 R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 9326 R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 9326 R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 9326 R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 9326 R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 9326 R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 9326 R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 9326 R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 9375 R-BTA-9657608 https://reactome.org/PathwayBrowser/#/R-BTA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Bos taurus 9375 R-CEL-9657608 https://reactome.org/PathwayBrowser/#/R-CEL-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Caenorhabditis elegans 9375 R-CFA-9657608 https://reactome.org/PathwayBrowser/#/R-CFA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Canis familiaris 9375 R-DME-9657608 https://reactome.org/PathwayBrowser/#/R-DME-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Drosophila melanogaster 9375 R-GGA-9657608 https://reactome.org/PathwayBrowser/#/R-GGA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Gallus gallus 9375 R-HSA-9657608 https://reactome.org/PathwayBrowser/#/R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK TAS Homo sapiens 9375 R-MMU-9657608 https://reactome.org/PathwayBrowser/#/R-MMU-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Mus musculus 9375 R-RNO-9657608 https://reactome.org/PathwayBrowser/#/R-RNO-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Rattus norvegicus 9375 R-SSC-9657608 https://reactome.org/PathwayBrowser/#/R-SSC-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK IEA Sus scrofa 9389 R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 9394 R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 9394 R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 9394 R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 9394 R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 9394 R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 9394 R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 9394 R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 9394 R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 9395 R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 9395 R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 9395 R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 9395 R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 9395 R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 9395 R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 9395 R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 9395 R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 9477 R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 9477 R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 9477 R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 9477 R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 9477 R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 9477 R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 9477 R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 9477 R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 9477 R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 9477 R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 9477 R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 9477 R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 9477 R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 9477 R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 9477 R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 9477 R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 9477 R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 9477 R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 9477 R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 9477 R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 9477 R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 9477 R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 948 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 948 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 948 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 948 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 948 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 948 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 948 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 948 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 948 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 948 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 9502 R-HSA-3139027 https://reactome.org/PathwayBrowser/#/R-HSA-3139027 Maturation of HIV Virion TAS Homo sapiens 9502 R-HSA-9697043 https://reactome.org/PathwayBrowser/#/R-HSA-9697043 Protease binds protease inhibitors TAS Homo sapiens 9512 R-BTA-9611839 https://reactome.org/PathwayBrowser/#/R-BTA-9611839 β3-agonists bind ADRB3 IEA Bos taurus 9512 R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 9512 R-CFA-9611839 https://reactome.org/PathwayBrowser/#/R-CFA-9611839 β3-agonists bind ADRB3 IEA Canis familiaris 9512 R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 9512 R-DME-9611839 https://reactome.org/PathwayBrowser/#/R-DME-9611839 β3-agonists bind ADRB3 IEA Drosophila melanogaster 9512 R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 9512 R-GGA-9611839 https://reactome.org/PathwayBrowser/#/R-GGA-9611839 β3-agonists bind ADRB3 IEA Gallus gallus 9512 R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 9512 R-HSA-9611839 https://reactome.org/PathwayBrowser/#/R-HSA-9611839 β3-agonists bind ADRB3 TAS Homo sapiens 9512 R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 9512 R-MMU-9611839 https://reactome.org/PathwayBrowser/#/R-MMU-9611839 β3-agonists bind ADRB3 IEA Mus musculus 9512 R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 9512 R-RNO-9611839 https://reactome.org/PathwayBrowser/#/R-RNO-9611839 β3-agonists bind ADRB3 IEA Rattus norvegicus 9512 R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 9512 R-SSC-9611839 https://reactome.org/PathwayBrowser/#/R-SSC-9611839 β3-agonists bind ADRB3 IEA Sus scrofa 9512 R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 9531 R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 9531 R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 9531 R-BTA-8953398 https://reactome.org/PathwayBrowser/#/R-BTA-8953398 PIR oxygenates quercetin IEA Bos taurus 9531 R-BTA-9707504 https://reactome.org/PathwayBrowser/#/R-BTA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Bos taurus 9531 R-BTA-9709317 https://reactome.org/PathwayBrowser/#/R-BTA-9709317 CO binds to free ferrohemoglobin IEA Bos taurus 9531 R-BTA-9709406 https://reactome.org/PathwayBrowser/#/R-BTA-9709406 CO binds to Cytochrome c oxidase IEA Bos taurus 9531 R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 9531 R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 9531 R-CFA-8953398 https://reactome.org/PathwayBrowser/#/R-CFA-8953398 PIR oxygenates quercetin IEA Canis familiaris 9531 R-CFA-9707504 https://reactome.org/PathwayBrowser/#/R-CFA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Canis familiaris 9531 R-CFA-9709317 https://reactome.org/PathwayBrowser/#/R-CFA-9709317 CO binds to free ferrohemoglobin IEA Canis familiaris 9531 R-CFA-9709406 https://reactome.org/PathwayBrowser/#/R-CFA-9709406 CO binds to Cytochrome c oxidase IEA Canis familiaris 9531 R-DDI-8953398 https://reactome.org/PathwayBrowser/#/R-DDI-8953398 PIR oxygenates quercetin IEA Dictyostelium discoideum 9531 R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 9531 R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 9531 R-DME-9709406 https://reactome.org/PathwayBrowser/#/R-DME-9709406 CO binds to Cytochrome c oxidase IEA Drosophila melanogaster 9531 R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 9531 R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 9531 R-DRE-9707504 https://reactome.org/PathwayBrowser/#/R-DRE-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Danio rerio 9531 R-DRE-9709317 https://reactome.org/PathwayBrowser/#/R-DRE-9709317 CO binds to free ferrohemoglobin IEA Danio rerio 9531 R-DRE-9709406 https://reactome.org/PathwayBrowser/#/R-DRE-9709406 CO binds to Cytochrome c oxidase IEA Danio rerio 9531 R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 9531 R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 9531 R-GGA-9707504 https://reactome.org/PathwayBrowser/#/R-GGA-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Gallus gallus 9531 R-GGA-9709317 https://reactome.org/PathwayBrowser/#/R-GGA-9709317 CO binds to free ferrohemoglobin IEA Gallus gallus 9531 R-GGA-9709406 https://reactome.org/PathwayBrowser/#/R-GGA-9709406 CO binds to Cytochrome c oxidase IEA Gallus gallus 9531 R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 9531 R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 9531 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 9531 R-HSA-8953398 https://reactome.org/PathwayBrowser/#/R-HSA-8953398 PIR oxygenates quercetin TAS Homo sapiens 9531 R-HSA-9707504 https://reactome.org/PathwayBrowser/#/R-HSA-9707504 H2O2 oxidises ferrohemoglobin to MetHb TAS Homo sapiens 9531 R-HSA-9709317 https://reactome.org/PathwayBrowser/#/R-HSA-9709317 CO binds to free ferrohemoglobin TAS Homo sapiens 9531 R-HSA-9709366 https://reactome.org/PathwayBrowser/#/R-HSA-9709366 CO translocates from cytosol to mitochondrial inner membrane TAS Homo sapiens 9531 R-HSA-9709396 https://reactome.org/PathwayBrowser/#/R-HSA-9709396 CO translocates from cytosol to extracellular region TAS Homo sapiens 9531 R-HSA-9709406 https://reactome.org/PathwayBrowser/#/R-HSA-9709406 CO binds to Cytochrome c oxidase TAS Homo sapiens 9531 R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 9531 R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 9531 R-MMU-8953398 https://reactome.org/PathwayBrowser/#/R-MMU-8953398 PIR oxygenates quercetin IEA Mus musculus 9531 R-MMU-9707504 https://reactome.org/PathwayBrowser/#/R-MMU-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Mus musculus 9531 R-MMU-9709317 https://reactome.org/PathwayBrowser/#/R-MMU-9709317 CO binds to free ferrohemoglobin IEA Mus musculus 9531 R-MMU-9709406 https://reactome.org/PathwayBrowser/#/R-MMU-9709406 CO binds to Cytochrome c oxidase IEA Mus musculus 9531 R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 9531 R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 9531 R-RNO-8953398 https://reactome.org/PathwayBrowser/#/R-RNO-8953398 PIR oxygenates quercetin IEA Rattus norvegicus 9531 R-RNO-9707504 https://reactome.org/PathwayBrowser/#/R-RNO-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Rattus norvegicus 9531 R-RNO-9709317 https://reactome.org/PathwayBrowser/#/R-RNO-9709317 CO binds to free ferrohemoglobin IEA Rattus norvegicus 9531 R-RNO-9709406 https://reactome.org/PathwayBrowser/#/R-RNO-9709406 CO binds to Cytochrome c oxidase IEA Rattus norvegicus 9531 R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 9531 R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 9531 R-SSC-8953398 https://reactome.org/PathwayBrowser/#/R-SSC-8953398 PIR oxygenates quercetin IEA Sus scrofa 9531 R-SSC-9707504 https://reactome.org/PathwayBrowser/#/R-SSC-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Sus scrofa 9531 R-SSC-9709317 https://reactome.org/PathwayBrowser/#/R-SSC-9709317 CO binds to free ferrohemoglobin IEA Sus scrofa 9531 R-SSC-9709406 https://reactome.org/PathwayBrowser/#/R-SSC-9709406 CO binds to Cytochrome c oxidase IEA Sus scrofa 9531 R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 9531 R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 9531 R-XTR-8953398 https://reactome.org/PathwayBrowser/#/R-XTR-8953398 PIR oxygenates quercetin IEA Xenopus tropicalis 9531 R-XTR-9707504 https://reactome.org/PathwayBrowser/#/R-XTR-9707504 H2O2 oxidises ferrohemoglobin to MetHb IEA Xenopus tropicalis 9531 R-XTR-9709317 https://reactome.org/PathwayBrowser/#/R-XTR-9709317 CO binds to free ferrohemoglobin IEA Xenopus tropicalis 9531 R-XTR-9709406 https://reactome.org/PathwayBrowser/#/R-XTR-9709406 CO binds to Cytochrome c oxidase IEA Xenopus tropicalis 96 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 96 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 96 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 96 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 96 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 96 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 96 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 96 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 96 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 96 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 96 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 96 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 96 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 96 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 96 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 96 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 96 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 96 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 96 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 96 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 9602 R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 9602 R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 9602 R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 9602 R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 9602 R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 9602 R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 9602 R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 9602 R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 9602 R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 9602 R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 9602 R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 9602 R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 9602 R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 9602 R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 9602 R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 9602 R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 9602 R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 9602 R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 9602 R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 9602 R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 9602 R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 9602 R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 9602 R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 9602 R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 9602 R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 9602 R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 9602 R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 9602 R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 9602 R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 9602 R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 9618 R-HSA-9681169 https://reactome.org/PathwayBrowser/#/R-HSA-9681169 CRBN binds IMiDs TAS Homo sapiens 9619 R-BTA-909720 https://reactome.org/PathwayBrowser/#/R-BTA-909720 IFN alpha/beta binds to IFNAR2 IEA Bos taurus 9619 R-BTA-9678561 https://reactome.org/PathwayBrowser/#/R-BTA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Bos taurus 9619 R-BTA-9678935 https://reactome.org/PathwayBrowser/#/R-BTA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Bos taurus 9619 R-CFA-909720 https://reactome.org/PathwayBrowser/#/R-CFA-909720 IFN alpha/beta binds to IFNAR2 IEA Canis familiaris 9619 R-CFA-9678561 https://reactome.org/PathwayBrowser/#/R-CFA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Canis familiaris 9619 R-CFA-9678935 https://reactome.org/PathwayBrowser/#/R-CFA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Canis familiaris 9619 R-DRE-9678561 https://reactome.org/PathwayBrowser/#/R-DRE-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Danio rerio 9619 R-GGA-909720 https://reactome.org/PathwayBrowser/#/R-GGA-909720 IFN alpha/beta binds to IFNAR2 IEA Gallus gallus 9619 R-GGA-9678561 https://reactome.org/PathwayBrowser/#/R-GGA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Gallus gallus 9619 R-GGA-9678935 https://reactome.org/PathwayBrowser/#/R-GGA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Gallus gallus 9619 R-HSA-909720 https://reactome.org/PathwayBrowser/#/R-HSA-909720 IFN alpha/beta binds to IFNAR2 TAS Homo sapiens 9619 R-HSA-9678561 https://reactome.org/PathwayBrowser/#/R-HSA-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors TAS Homo sapiens 9619 R-HSA-9678935 https://reactome.org/PathwayBrowser/#/R-HSA-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors TAS Homo sapiens 9619 R-MMU-909720 https://reactome.org/PathwayBrowser/#/R-MMU-909720 IFN alpha/beta binds to IFNAR2 IEA Mus musculus 9619 R-MMU-9678561 https://reactome.org/PathwayBrowser/#/R-MMU-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Mus musculus 9619 R-MMU-9678935 https://reactome.org/PathwayBrowser/#/R-MMU-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Mus musculus 9619 R-RNO-909720 https://reactome.org/PathwayBrowser/#/R-RNO-909720 IFN alpha/beta binds to IFNAR2 IEA Rattus norvegicus 9619 R-RNO-9678561 https://reactome.org/PathwayBrowser/#/R-RNO-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Rattus norvegicus 9619 R-RNO-9678935 https://reactome.org/PathwayBrowser/#/R-RNO-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Rattus norvegicus 9619 R-SSC-909720 https://reactome.org/PathwayBrowser/#/R-SSC-909720 IFN alpha/beta binds to IFNAR2 IEA Sus scrofa 9619 R-SSC-9678561 https://reactome.org/PathwayBrowser/#/R-SSC-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Sus scrofa 9619 R-SSC-9678935 https://reactome.org/PathwayBrowser/#/R-SSC-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Sus scrofa 9619 R-XTR-9678561 https://reactome.org/PathwayBrowser/#/R-XTR-9678561 IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 9619 R-XTR-9678935 https://reactome.org/PathwayBrowser/#/R-XTR-9678935 IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors IEA Xenopus tropicalis 9626 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 9626 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 9626 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 9626 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 9626 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 9626 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 9626 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 9626 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 9626 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 9626 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 9626 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 9626 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 9626 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 9626 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 9626 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 9626 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 9626 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 9626 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 9626 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 9626 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 9626 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 9626 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 9626 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 9626 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 9626 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 9626 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 9626 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 9626 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 9626 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 963 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 963 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 963 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 963 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 963 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 963 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 963 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 963 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 963 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 963 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 9635 R-BTA-9718020 https://reactome.org/PathwayBrowser/#/R-BTA-9718020 PTGFR binds PTGFR agonists IEA Bos taurus 9635 R-CFA-9718020 https://reactome.org/PathwayBrowser/#/R-CFA-9718020 PTGFR binds PTGFR agonists IEA Canis familiaris 9635 R-DME-9718020 https://reactome.org/PathwayBrowser/#/R-DME-9718020 PTGFR binds PTGFR agonists IEA Drosophila melanogaster 9635 R-DRE-9718020 https://reactome.org/PathwayBrowser/#/R-DRE-9718020 PTGFR binds PTGFR agonists IEA Danio rerio 9635 R-GGA-9718020 https://reactome.org/PathwayBrowser/#/R-GGA-9718020 PTGFR binds PTGFR agonists IEA Gallus gallus 9635 R-HSA-9718020 https://reactome.org/PathwayBrowser/#/R-HSA-9718020 PTGFR binds PTGFR agonists TAS Homo sapiens 9635 R-MMU-9718020 https://reactome.org/PathwayBrowser/#/R-MMU-9718020 PTGFR binds PTGFR agonists IEA Mus musculus 9635 R-RNO-9718020 https://reactome.org/PathwayBrowser/#/R-RNO-9718020 PTGFR binds PTGFR agonists IEA Rattus norvegicus 9635 R-SSC-9718020 https://reactome.org/PathwayBrowser/#/R-SSC-9718020 PTGFR binds PTGFR agonists IEA Sus scrofa 9635 R-XTR-9718020 https://reactome.org/PathwayBrowser/#/R-XTR-9718020 PTGFR binds PTGFR agonists IEA Xenopus tropicalis 9642 R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 9642 R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 9642 R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 9642 R-BTA-8936849 https://reactome.org/PathwayBrowser/#/R-BTA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Bos taurus 9642 R-BTA-8937169 https://reactome.org/PathwayBrowser/#/R-BTA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Bos taurus 9642 R-BTA-8937177 https://reactome.org/PathwayBrowser/#/R-BTA-8937177 AHR:TCDD binds ARNT IEA Bos taurus 9642 R-BTA-8937191 https://reactome.org/PathwayBrowser/#/R-BTA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Bos taurus 9642 R-CEL-8936849 https://reactome.org/PathwayBrowser/#/R-CEL-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Caenorhabditis elegans 9642 R-CEL-8937169 https://reactome.org/PathwayBrowser/#/R-CEL-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Caenorhabditis elegans 9642 R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 9642 R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 9642 R-CFA-8936849 https://reactome.org/PathwayBrowser/#/R-CFA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Canis familiaris 9642 R-CFA-8937169 https://reactome.org/PathwayBrowser/#/R-CFA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Canis familiaris 9642 R-CFA-8937177 https://reactome.org/PathwayBrowser/#/R-CFA-8937177 AHR:TCDD binds ARNT IEA Canis familiaris 9642 R-DDI-8936849 https://reactome.org/PathwayBrowser/#/R-DDI-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Dictyostelium discoideum 9642 R-DDI-8937169 https://reactome.org/PathwayBrowser/#/R-DDI-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Dictyostelium discoideum 9642 R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 9642 R-DME-8936849 https://reactome.org/PathwayBrowser/#/R-DME-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Drosophila melanogaster 9642 R-DME-8937169 https://reactome.org/PathwayBrowser/#/R-DME-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Drosophila melanogaster 9642 R-DME-8937177 https://reactome.org/PathwayBrowser/#/R-DME-8937177 AHR:TCDD binds ARNT IEA Drosophila melanogaster 9642 R-DME-8937191 https://reactome.org/PathwayBrowser/#/R-DME-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Drosophila melanogaster 9642 R-DRE-8936849 https://reactome.org/PathwayBrowser/#/R-DRE-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Danio rerio 9642 R-DRE-8937169 https://reactome.org/PathwayBrowser/#/R-DRE-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Danio rerio 9642 R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 9642 R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 9642 R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 9642 R-GGA-8936849 https://reactome.org/PathwayBrowser/#/R-GGA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Gallus gallus 9642 R-GGA-8937169 https://reactome.org/PathwayBrowser/#/R-GGA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Gallus gallus 9642 R-GGA-8937177 https://reactome.org/PathwayBrowser/#/R-GGA-8937177 AHR:TCDD binds ARNT IEA Gallus gallus 9642 R-GGA-8937191 https://reactome.org/PathwayBrowser/#/R-GGA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Gallus gallus 9642 R-HSA-1989764 https://reactome.org/PathwayBrowser/#/R-HSA-1989764 Expression of CYP1A1 TAS Homo sapiens 9642 R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 9642 R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 9642 R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 9642 R-HSA-8936849 https://reactome.org/PathwayBrowser/#/R-HSA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD TAS Homo sapiens 9642 R-HSA-8937169 https://reactome.org/PathwayBrowser/#/R-HSA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm TAS Homo sapiens 9642 R-HSA-8937177 https://reactome.org/PathwayBrowser/#/R-HSA-8937177 AHR:TCDD binds ARNT TAS Homo sapiens 9642 R-HSA-8937191 https://reactome.org/PathwayBrowser/#/R-HSA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates TAS Homo sapiens 9642 R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 9642 R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 9642 R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 9642 R-MMU-8936849 https://reactome.org/PathwayBrowser/#/R-MMU-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Mus musculus 9642 R-MMU-8937169 https://reactome.org/PathwayBrowser/#/R-MMU-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Mus musculus 9642 R-MMU-8937177 https://reactome.org/PathwayBrowser/#/R-MMU-8937177 AHR:TCDD binds ARNT IEA Mus musculus 9642 R-MMU-8937191 https://reactome.org/PathwayBrowser/#/R-MMU-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Mus musculus 9642 R-PFA-8936849 https://reactome.org/PathwayBrowser/#/R-PFA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Plasmodium falciparum 9642 R-PFA-8937169 https://reactome.org/PathwayBrowser/#/R-PFA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Plasmodium falciparum 9642 R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 9642 R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 9642 R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 9642 R-RNO-8936849 https://reactome.org/PathwayBrowser/#/R-RNO-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Rattus norvegicus 9642 R-RNO-8937169 https://reactome.org/PathwayBrowser/#/R-RNO-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Rattus norvegicus 9642 R-RNO-8937177 https://reactome.org/PathwayBrowser/#/R-RNO-8937177 AHR:TCDD binds ARNT IEA Rattus norvegicus 9642 R-RNO-8937191 https://reactome.org/PathwayBrowser/#/R-RNO-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Rattus norvegicus 9642 R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 9642 R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 9642 R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 9642 R-SSC-8936849 https://reactome.org/PathwayBrowser/#/R-SSC-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Sus scrofa 9642 R-SSC-8937169 https://reactome.org/PathwayBrowser/#/R-SSC-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Sus scrofa 9642 R-SSC-8937177 https://reactome.org/PathwayBrowser/#/R-SSC-8937177 AHR:TCDD binds ARNT IEA Sus scrofa 9642 R-SSC-8937191 https://reactome.org/PathwayBrowser/#/R-SSC-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Sus scrofa 9642 R-XTR-8936849 https://reactome.org/PathwayBrowser/#/R-XTR-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD IEA Xenopus tropicalis 9642 R-XTR-8937169 https://reactome.org/PathwayBrowser/#/R-XTR-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm IEA Xenopus tropicalis 9642 R-XTR-8937177 https://reactome.org/PathwayBrowser/#/R-XTR-8937177 AHR:TCDD binds ARNT IEA Xenopus tropicalis 9642 R-XTR-8937191 https://reactome.org/PathwayBrowser/#/R-XTR-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates IEA Xenopus tropicalis 965 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 965 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 965 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 965 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 965 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 965 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 965 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 965 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 965 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 965 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 9704 R-BTA-445753 https://reactome.org/PathwayBrowser/#/R-BTA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Bos taurus 9704 R-BTA-9681763 https://reactome.org/PathwayBrowser/#/R-BTA-9681763 IL1R1 binds IL1R1 inhibitors IEA Bos taurus 9704 R-CFA-445753 https://reactome.org/PathwayBrowser/#/R-CFA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Canis familiaris 9704 R-CFA-9681763 https://reactome.org/PathwayBrowser/#/R-CFA-9681763 IL1R1 binds IL1R1 inhibitors IEA Canis familiaris 9704 R-GGA-445753 https://reactome.org/PathwayBrowser/#/R-GGA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Gallus gallus 9704 R-GGA-9681763 https://reactome.org/PathwayBrowser/#/R-GGA-9681763 IL1R1 binds IL1R1 inhibitors IEA Gallus gallus 9704 R-HSA-445753 https://reactome.org/PathwayBrowser/#/R-HSA-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 TAS Homo sapiens 9704 R-HSA-9681763 https://reactome.org/PathwayBrowser/#/R-HSA-9681763 IL1R1 binds IL1R1 inhibitors TAS Homo sapiens 9704 R-MMU-445753 https://reactome.org/PathwayBrowser/#/R-MMU-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Mus musculus 9704 R-MMU-9681763 https://reactome.org/PathwayBrowser/#/R-MMU-9681763 IL1R1 binds IL1R1 inhibitors IEA Mus musculus 9704 R-RNO-445753 https://reactome.org/PathwayBrowser/#/R-RNO-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Rattus norvegicus 9704 R-RNO-9681763 https://reactome.org/PathwayBrowser/#/R-RNO-9681763 IL1R1 binds IL1R1 inhibitors IEA Rattus norvegicus 9704 R-SSC-445753 https://reactome.org/PathwayBrowser/#/R-SSC-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Sus scrofa 9704 R-SSC-9681763 https://reactome.org/PathwayBrowser/#/R-SSC-9681763 IL1R1 binds IL1R1 inhibitors IEA Sus scrofa 9704 R-XTR-445753 https://reactome.org/PathwayBrowser/#/R-XTR-445753 IL1B,Myr82K-Myr83K-IL1A:IL1R1 IEA Xenopus tropicalis 9704 R-XTR-9681763 https://reactome.org/PathwayBrowser/#/R-XTR-9681763 IL1R1 binds IL1R1 inhibitors IEA Xenopus tropicalis 9711 R-BTA-9716947 https://reactome.org/PathwayBrowser/#/R-BTA-9716947 ESR1 binds ESR1 agonists IEA Bos taurus 9711 R-DME-9716947 https://reactome.org/PathwayBrowser/#/R-DME-9716947 ESR1 binds ESR1 agonists IEA Drosophila melanogaster 9711 R-DRE-9716947 https://reactome.org/PathwayBrowser/#/R-DRE-9716947 ESR1 binds ESR1 agonists IEA Danio rerio 9711 R-GGA-9716947 https://reactome.org/PathwayBrowser/#/R-GGA-9716947 ESR1 binds ESR1 agonists IEA Gallus gallus 9711 R-HSA-9716947 https://reactome.org/PathwayBrowser/#/R-HSA-9716947 ESR1 binds ESR1 agonists TAS Homo sapiens 9711 R-MMU-9716947 https://reactome.org/PathwayBrowser/#/R-MMU-9716947 ESR1 binds ESR1 agonists IEA Mus musculus 9711 R-RNO-9716947 https://reactome.org/PathwayBrowser/#/R-RNO-9716947 ESR1 binds ESR1 agonists IEA Rattus norvegicus 9711 R-SSC-9716947 https://reactome.org/PathwayBrowser/#/R-SSC-9716947 ESR1 binds ESR1 agonists IEA Sus scrofa 9711 R-XTR-9716947 https://reactome.org/PathwayBrowser/#/R-XTR-9716947 ESR1 binds ESR1 agonists IEA Xenopus tropicalis 9724 R-BTA-9728664 https://reactome.org/PathwayBrowser/#/R-BTA-9728664 GLP1R binds GLP1R agonists IEA Bos taurus 9724 R-CFA-9728664 https://reactome.org/PathwayBrowser/#/R-CFA-9728664 GLP1R binds GLP1R agonists IEA Canis familiaris 9724 R-DRE-9728664 https://reactome.org/PathwayBrowser/#/R-DRE-9728664 GLP1R binds GLP1R agonists IEA Danio rerio 9724 R-HSA-9728664 https://reactome.org/PathwayBrowser/#/R-HSA-9728664 GLP1R binds GLP1R agonists TAS Homo sapiens 9724 R-MMU-9728664 https://reactome.org/PathwayBrowser/#/R-MMU-9728664 GLP1R binds GLP1R agonists IEA Mus musculus 9724 R-RNO-9728664 https://reactome.org/PathwayBrowser/#/R-RNO-9728664 GLP1R binds GLP1R agonists IEA Rattus norvegicus 9724 R-SSC-9728664 https://reactome.org/PathwayBrowser/#/R-SSC-9728664 GLP1R binds GLP1R agonists IEA Sus scrofa 9730 R-BTA-9702849 https://reactome.org/PathwayBrowser/#/R-BTA-9702849 CALCR binds gepants IEA Bos taurus 9730 R-CEL-9702849 https://reactome.org/PathwayBrowser/#/R-CEL-9702849 CALCR binds gepants IEA Caenorhabditis elegans 9730 R-CFA-9702849 https://reactome.org/PathwayBrowser/#/R-CFA-9702849 CALCR binds gepants IEA Canis familiaris 9730 R-DME-9702849 https://reactome.org/PathwayBrowser/#/R-DME-9702849 CALCR binds gepants IEA Drosophila melanogaster 9730 R-GGA-9702849 https://reactome.org/PathwayBrowser/#/R-GGA-9702849 CALCR binds gepants IEA Gallus gallus 9730 R-HSA-9702849 https://reactome.org/PathwayBrowser/#/R-HSA-9702849 CALCR binds gepants TAS Homo sapiens 9730 R-MMU-9702849 https://reactome.org/PathwayBrowser/#/R-MMU-9702849 CALCR binds gepants IEA Mus musculus 9730 R-RNO-9702849 https://reactome.org/PathwayBrowser/#/R-RNO-9702849 CALCR binds gepants IEA Rattus norvegicus 9730 R-SSC-9702849 https://reactome.org/PathwayBrowser/#/R-SSC-9702849 CALCR binds gepants IEA Sus scrofa 9730 R-XTR-9702849 https://reactome.org/PathwayBrowser/#/R-XTR-9702849 CALCR binds gepants IEA Xenopus tropicalis 9758 R-BTA-388828 https://reactome.org/PathwayBrowser/#/R-BTA-388828 PD-1 binds B7DC and B7H1 IEA Bos taurus 9758 R-BTA-9679421 https://reactome.org/PathwayBrowser/#/R-BTA-9679421 PDCD1 binds PDCD1 inhibitors IEA Bos taurus 9758 R-BTA-9936162 https://reactome.org/PathwayBrowser/#/R-BTA-9936162 PD-1 binds PD-L1,PD-L2 IEA Bos taurus 9758 R-CFA-388828 https://reactome.org/PathwayBrowser/#/R-CFA-388828 PD-1 binds B7DC and B7H1 IEA Canis familiaris 9758 R-CFA-9679421 https://reactome.org/PathwayBrowser/#/R-CFA-9679421 PDCD1 binds PDCD1 inhibitors IEA Canis familiaris 9758 R-CFA-9936162 https://reactome.org/PathwayBrowser/#/R-CFA-9936162 PD-1 binds PD-L1,PD-L2 IEA Canis familiaris 9758 R-GGA-388828 https://reactome.org/PathwayBrowser/#/R-GGA-388828 PD-1 binds B7DC and B7H1 IEA Gallus gallus 9758 R-GGA-9679421 https://reactome.org/PathwayBrowser/#/R-GGA-9679421 PDCD1 binds PDCD1 inhibitors IEA Gallus gallus 9758 R-GGA-9936162 https://reactome.org/PathwayBrowser/#/R-GGA-9936162 PD-1 binds PD-L1,PD-L2 IEA Gallus gallus 9758 R-HSA-388828 https://reactome.org/PathwayBrowser/#/R-HSA-388828 PD-1 binds B7DC and B7H1 TAS Homo sapiens 9758 R-HSA-9679421 https://reactome.org/PathwayBrowser/#/R-HSA-9679421 PDCD1 binds PDCD1 inhibitors TAS Homo sapiens 9758 R-HSA-9936162 https://reactome.org/PathwayBrowser/#/R-HSA-9936162 PD-1 binds PD-L1,PD-L2 TAS Homo sapiens 9758 R-MMU-388828 https://reactome.org/PathwayBrowser/#/R-MMU-388828 PD-1 binds B7DC and B7H1 IEA Mus musculus 9758 R-MMU-9679421 https://reactome.org/PathwayBrowser/#/R-MMU-9679421 PDCD1 binds PDCD1 inhibitors IEA Mus musculus 9758 R-MMU-9936162 https://reactome.org/PathwayBrowser/#/R-MMU-9936162 PD-1 binds PD-L1,PD-L2 IEA Mus musculus 9758 R-RNO-388828 https://reactome.org/PathwayBrowser/#/R-RNO-388828 PD-1 binds B7DC and B7H1 IEA Rattus norvegicus 9758 R-RNO-9679421 https://reactome.org/PathwayBrowser/#/R-RNO-9679421 PDCD1 binds PDCD1 inhibitors IEA Rattus norvegicus 9758 R-RNO-9936162 https://reactome.org/PathwayBrowser/#/R-RNO-9936162 PD-1 binds PD-L1,PD-L2 IEA Rattus norvegicus 9758 R-SSC-388828 https://reactome.org/PathwayBrowser/#/R-SSC-388828 PD-1 binds B7DC and B7H1 IEA Sus scrofa 9758 R-SSC-9679421 https://reactome.org/PathwayBrowser/#/R-SSC-9679421 PDCD1 binds PDCD1 inhibitors IEA Sus scrofa 9758 R-SSC-9936162 https://reactome.org/PathwayBrowser/#/R-SSC-9936162 PD-1 binds PD-L1,PD-L2 IEA Sus scrofa 98 R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 98 R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 98 R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 98 R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 98 R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 98 R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 98 R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 98 R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 98 R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 98 R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 98 R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 98 R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 98 R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 98 R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 98 R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 98 R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 98 R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 98 R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 98 R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 98 R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 9826 R-HSA-2400009 https://reactome.org/PathwayBrowser/#/R-HSA-2400009 PI3K inhibitors block PI3K catalytic activity TAS Homo sapiens 9827 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 9828 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 9829 R-HSA-1218824 https://reactome.org/PathwayBrowser/#/R-HSA-1218824 HSP90 is inactivated by binding to benzaquinoid ansamycins TAS Homo sapiens 9830 R-BTA-9013533 https://reactome.org/PathwayBrowser/#/R-BTA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Bos taurus 9830 R-CEL-9013533 https://reactome.org/PathwayBrowser/#/R-CEL-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Caenorhabditis elegans 9830 R-CFA-9013533 https://reactome.org/PathwayBrowser/#/R-CFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Canis familiaris 9830 R-DDI-9013533 https://reactome.org/PathwayBrowser/#/R-DDI-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Dictyostelium discoideum 9830 R-DRE-9013533 https://reactome.org/PathwayBrowser/#/R-DRE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Danio rerio 9830 R-GGA-9013533 https://reactome.org/PathwayBrowser/#/R-GGA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Gallus gallus 9830 R-HSA-9013533 https://reactome.org/PathwayBrowser/#/R-HSA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN TAS Homo sapiens 9830 R-MMU-9013533 https://reactome.org/PathwayBrowser/#/R-MMU-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Mus musculus 9830 R-PFA-9013533 https://reactome.org/PathwayBrowser/#/R-PFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Plasmodium falciparum 9830 R-RNO-9013533 https://reactome.org/PathwayBrowser/#/R-RNO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Rattus norvegicus 9830 R-SCE-9013533 https://reactome.org/PathwayBrowser/#/R-SCE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Saccharomyces cerevisiae 9830 R-SPO-9013533 https://reactome.org/PathwayBrowser/#/R-SPO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Schizosaccharomyces pombe 9830 R-SSC-9013533 https://reactome.org/PathwayBrowser/#/R-SSC-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Sus scrofa 9830 R-XTR-9013533 https://reactome.org/PathwayBrowser/#/R-XTR-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Xenopus tropicalis 9847 R-BTA-9689680 https://reactome.org/PathwayBrowser/#/R-BTA-9689680 IFNG dimer binds IFNG inhibitors IEA Bos taurus 9847 R-CFA-9689680 https://reactome.org/PathwayBrowser/#/R-CFA-9689680 IFNG dimer binds IFNG inhibitors IEA Canis familiaris 9847 R-DRE-9689680 https://reactome.org/PathwayBrowser/#/R-DRE-9689680 IFNG dimer binds IFNG inhibitors IEA Danio rerio 9847 R-GGA-9689680 https://reactome.org/PathwayBrowser/#/R-GGA-9689680 IFNG dimer binds IFNG inhibitors IEA Gallus gallus 9847 R-HSA-9689680 https://reactome.org/PathwayBrowser/#/R-HSA-9689680 IFNG dimer binds IFNG inhibitors TAS Homo sapiens 9847 R-MMU-9689680 https://reactome.org/PathwayBrowser/#/R-MMU-9689680 IFNG dimer binds IFNG inhibitors IEA Mus musculus 9847 R-RNO-9689680 https://reactome.org/PathwayBrowser/#/R-RNO-9689680 IFNG dimer binds IFNG inhibitors IEA Rattus norvegicus 9847 R-SSC-9689680 https://reactome.org/PathwayBrowser/#/R-SSC-9689680 IFNG dimer binds IFNG inhibitors IEA Sus scrofa 9860 R-BTA-9708759 https://reactome.org/PathwayBrowser/#/R-BTA-9708759 DHODH:FMN binds DHODH inhibitors IEA Bos taurus 9860 R-CEL-9708759 https://reactome.org/PathwayBrowser/#/R-CEL-9708759 DHODH:FMN binds DHODH inhibitors IEA Caenorhabditis elegans 9860 R-CFA-9708759 https://reactome.org/PathwayBrowser/#/R-CFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Canis familiaris 9860 R-DME-9708759 https://reactome.org/PathwayBrowser/#/R-DME-9708759 DHODH:FMN binds DHODH inhibitors IEA Drosophila melanogaster 9860 R-DRE-9708759 https://reactome.org/PathwayBrowser/#/R-DRE-9708759 DHODH:FMN binds DHODH inhibitors IEA Danio rerio 9860 R-GGA-9708759 https://reactome.org/PathwayBrowser/#/R-GGA-9708759 DHODH:FMN binds DHODH inhibitors IEA Gallus gallus 9860 R-HSA-9708759 https://reactome.org/PathwayBrowser/#/R-HSA-9708759 DHODH:FMN binds DHODH inhibitors TAS Homo sapiens 9860 R-MMU-9708759 https://reactome.org/PathwayBrowser/#/R-MMU-9708759 DHODH:FMN binds DHODH inhibitors IEA Mus musculus 9860 R-PFA-9708759 https://reactome.org/PathwayBrowser/#/R-PFA-9708759 DHODH:FMN binds DHODH inhibitors IEA Plasmodium falciparum 9860 R-RNO-9708759 https://reactome.org/PathwayBrowser/#/R-RNO-9708759 DHODH:FMN binds DHODH inhibitors IEA Rattus norvegicus 9860 R-SPO-9708759 https://reactome.org/PathwayBrowser/#/R-SPO-9708759 DHODH:FMN binds DHODH inhibitors IEA Schizosaccharomyces pombe 9860 R-SSC-9708759 https://reactome.org/PathwayBrowser/#/R-SSC-9708759 DHODH:FMN binds DHODH inhibitors IEA Sus scrofa 9860 R-XTR-9708759 https://reactome.org/PathwayBrowser/#/R-XTR-9708759 DHODH:FMN binds DHODH inhibitors IEA Xenopus tropicalis 9861 R-BTA-9691421 https://reactome.org/PathwayBrowser/#/R-BTA-9691421 BTK binds BTK inhibitors IEA Bos taurus 9861 R-CFA-9691421 https://reactome.org/PathwayBrowser/#/R-CFA-9691421 BTK binds BTK inhibitors IEA Canis familiaris 9861 R-GGA-9691421 https://reactome.org/PathwayBrowser/#/R-GGA-9691421 BTK binds BTK inhibitors IEA Gallus gallus 9861 R-HSA-9691421 https://reactome.org/PathwayBrowser/#/R-HSA-9691421 BTK binds BTK inhibitors TAS Homo sapiens 9861 R-MMU-9691421 https://reactome.org/PathwayBrowser/#/R-MMU-9691421 BTK binds BTK inhibitors IEA Mus musculus 9861 R-RNO-9691421 https://reactome.org/PathwayBrowser/#/R-RNO-9691421 BTK binds BTK inhibitors IEA Rattus norvegicus 9861 R-SSC-9691421 https://reactome.org/PathwayBrowser/#/R-SSC-9691421 BTK binds BTK inhibitors IEA Sus scrofa 9900 R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 9900 R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 9900 R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 9900 R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 9900 R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 9900 R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 9900 R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 9900 R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 9900 R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 9900 R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 9906 R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 9906 R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 9906 R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 9906 R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 9906 R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 9906 R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 9906 R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 9906 R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 9906 R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 9906 R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 9906 R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 9906 R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 9909 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 9909 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 9909 R-BTA-9657599 https://reactome.org/PathwayBrowser/#/R-BTA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Bos taurus 9909 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 9909 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 9909 R-CEL-9657599 https://reactome.org/PathwayBrowser/#/R-CEL-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Caenorhabditis elegans 9909 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 9909 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 9909 R-CFA-9657599 https://reactome.org/PathwayBrowser/#/R-CFA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Canis familiaris 9909 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 9909 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 9909 R-DME-9657599 https://reactome.org/PathwayBrowser/#/R-DME-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Drosophila melanogaster 9909 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 9909 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 9909 R-GGA-9657599 https://reactome.org/PathwayBrowser/#/R-GGA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Gallus gallus 9909 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 9909 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 9909 R-HSA-9657599 https://reactome.org/PathwayBrowser/#/R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks TAS Homo sapiens 9909 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 9909 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 9909 R-MMU-9657599 https://reactome.org/PathwayBrowser/#/R-MMU-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Mus musculus 9909 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 9909 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 9909 R-RNO-9657599 https://reactome.org/PathwayBrowser/#/R-RNO-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Rattus norvegicus 9909 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 9909 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 9909 R-SSC-9657599 https://reactome.org/PathwayBrowser/#/R-SSC-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks IEA Sus scrofa 9918 R-BTA-6806974 https://reactome.org/PathwayBrowser/#/R-BTA-6806974 MET dimers autophosphorylate IEA Bos taurus 9918 R-BTA-9735946 https://reactome.org/PathwayBrowser/#/R-BTA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Bos taurus 9918 R-CEL-6806974 https://reactome.org/PathwayBrowser/#/R-CEL-6806974 MET dimers autophosphorylate IEA Caenorhabditis elegans 9918 R-CEL-9735946 https://reactome.org/PathwayBrowser/#/R-CEL-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Caenorhabditis elegans 9918 R-CFA-6806974 https://reactome.org/PathwayBrowser/#/R-CFA-6806974 MET dimers autophosphorylate IEA Canis familiaris 9918 R-CFA-9735946 https://reactome.org/PathwayBrowser/#/R-CFA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Canis familiaris 9918 R-GGA-6806974 https://reactome.org/PathwayBrowser/#/R-GGA-6806974 MET dimers autophosphorylate IEA Gallus gallus 9918 R-GGA-9735946 https://reactome.org/PathwayBrowser/#/R-GGA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Gallus gallus 9918 R-HSA-6806974 https://reactome.org/PathwayBrowser/#/R-HSA-6806974 MET dimers autophosphorylate TAS Homo sapiens 9918 R-HSA-9735946 https://reactome.org/PathwayBrowser/#/R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET TAS Homo sapiens 9918 R-MMU-6806974 https://reactome.org/PathwayBrowser/#/R-MMU-6806974 MET dimers autophosphorylate IEA Mus musculus 9918 R-MMU-9735946 https://reactome.org/PathwayBrowser/#/R-MMU-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Mus musculus 9918 R-RNO-6806974 https://reactome.org/PathwayBrowser/#/R-RNO-6806974 MET dimers autophosphorylate IEA Rattus norvegicus 9918 R-RNO-9735946 https://reactome.org/PathwayBrowser/#/R-RNO-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Rattus norvegicus 9918 R-SSC-6806974 https://reactome.org/PathwayBrowser/#/R-SSC-6806974 MET dimers autophosphorylate IEA Sus scrofa 9918 R-SSC-9735946 https://reactome.org/PathwayBrowser/#/R-SSC-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Sus scrofa 9918 R-XTR-6806974 https://reactome.org/PathwayBrowser/#/R-XTR-6806974 MET dimers autophosphorylate IEA Xenopus tropicalis 9918 R-XTR-9735946 https://reactome.org/PathwayBrowser/#/R-XTR-9735946 Anti-MET small tyrosine kinase inhibitors bind MET IEA Xenopus tropicalis 9923 R-BTA-69227 https://reactome.org/PathwayBrowser/#/R-BTA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Bos taurus 9923 R-BTA-9754129 https://reactome.org/PathwayBrowser/#/R-BTA-9754129 CDK6 inhibitors bind CDK6 IEA Bos taurus 9923 R-BTA-9754130 https://reactome.org/PathwayBrowser/#/R-BTA-9754130 CDK4 inhibitors bind CDK4 IEA Bos taurus 9923 R-CFA-69227 https://reactome.org/PathwayBrowser/#/R-CFA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Canis familiaris 9923 R-CFA-9754129 https://reactome.org/PathwayBrowser/#/R-CFA-9754129 CDK6 inhibitors bind CDK6 IEA Canis familiaris 9923 R-CFA-9754130 https://reactome.org/PathwayBrowser/#/R-CFA-9754130 CDK4 inhibitors bind CDK4 IEA Canis familiaris 9923 R-DME-9754129 https://reactome.org/PathwayBrowser/#/R-DME-9754129 CDK6 inhibitors bind CDK6 IEA Drosophila melanogaster 9923 R-DME-9754130 https://reactome.org/PathwayBrowser/#/R-DME-9754130 CDK4 inhibitors bind CDK4 IEA Drosophila melanogaster 9923 R-DRE-69227 https://reactome.org/PathwayBrowser/#/R-DRE-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Danio rerio 9923 R-DRE-9754130 https://reactome.org/PathwayBrowser/#/R-DRE-9754130 CDK4 inhibitors bind CDK4 IEA Danio rerio 9923 R-GGA-69227 https://reactome.org/PathwayBrowser/#/R-GGA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Gallus gallus 9923 R-GGA-9754129 https://reactome.org/PathwayBrowser/#/R-GGA-9754129 CDK6 inhibitors bind CDK6 IEA Gallus gallus 9923 R-HSA-69227 https://reactome.org/PathwayBrowser/#/R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes TAS Homo sapiens 9923 R-HSA-9754129 https://reactome.org/PathwayBrowser/#/R-HSA-9754129 CDK6 inhibitors bind CDK6 TAS Homo sapiens 9923 R-HSA-9754130 https://reactome.org/PathwayBrowser/#/R-HSA-9754130 CDK4 inhibitors bind CDK4 TAS Homo sapiens 9923 R-MMU-69227 https://reactome.org/PathwayBrowser/#/R-MMU-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Mus musculus 9923 R-MMU-9754129 https://reactome.org/PathwayBrowser/#/R-MMU-9754129 CDK6 inhibitors bind CDK6 IEA Mus musculus 9923 R-MMU-9754130 https://reactome.org/PathwayBrowser/#/R-MMU-9754130 CDK4 inhibitors bind CDK4 IEA Mus musculus 9923 R-RNO-69227 https://reactome.org/PathwayBrowser/#/R-RNO-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Rattus norvegicus 9923 R-RNO-9754129 https://reactome.org/PathwayBrowser/#/R-RNO-9754129 CDK6 inhibitors bind CDK6 IEA Rattus norvegicus 9923 R-RNO-9754130 https://reactome.org/PathwayBrowser/#/R-RNO-9754130 CDK4 inhibitors bind CDK4 IEA Rattus norvegicus 9923 R-SPO-9754129 https://reactome.org/PathwayBrowser/#/R-SPO-9754129 CDK6 inhibitors bind CDK6 IEA Schizosaccharomyces pombe 9923 R-SPO-9754130 https://reactome.org/PathwayBrowser/#/R-SPO-9754130 CDK4 inhibitors bind CDK4 IEA Schizosaccharomyces pombe 9923 R-SSC-69227 https://reactome.org/PathwayBrowser/#/R-SSC-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Sus scrofa 9923 R-SSC-9754129 https://reactome.org/PathwayBrowser/#/R-SSC-9754129 CDK6 inhibitors bind CDK6 IEA Sus scrofa 9923 R-SSC-9754130 https://reactome.org/PathwayBrowser/#/R-SSC-9754130 CDK4 inhibitors bind CDK4 IEA Sus scrofa 9923 R-XTR-69227 https://reactome.org/PathwayBrowser/#/R-XTR-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes IEA Xenopus tropicalis 9923 R-XTR-9754129 https://reactome.org/PathwayBrowser/#/R-XTR-9754129 CDK6 inhibitors bind CDK6 IEA Xenopus tropicalis 9923 R-XTR-9754130 https://reactome.org/PathwayBrowser/#/R-XTR-9754130 CDK4 inhibitors bind CDK4 IEA Xenopus tropicalis 9974 R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 9974 R-BTA-9657603 https://reactome.org/PathwayBrowser/#/R-BTA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Bos taurus 9974 R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 9974 R-CEL-9657603 https://reactome.org/PathwayBrowser/#/R-CEL-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Caenorhabditis elegans 9974 R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 9974 R-CFA-9657603 https://reactome.org/PathwayBrowser/#/R-CFA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Canis familiaris 9974 R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 9974 R-DME-9657603 https://reactome.org/PathwayBrowser/#/R-DME-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Drosophila melanogaster 9974 R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 9974 R-GGA-9657603 https://reactome.org/PathwayBrowser/#/R-GGA-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Gallus gallus 9974 R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 9974 R-HSA-9657603 https://reactome.org/PathwayBrowser/#/R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs TAS Homo sapiens 9974 R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 9974 R-MMU-9657603 https://reactome.org/PathwayBrowser/#/R-MMU-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Mus musculus 9974 R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 9974 R-RNO-9657603 https://reactome.org/PathwayBrowser/#/R-RNO-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Rattus norvegicus 9974 R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 9974 R-SSC-9657603 https://reactome.org/PathwayBrowser/#/R-SSC-9657603 Dual mechanism MAPK inhibitors bind MAPKs IEA Sus scrofa 9977 R-BTA-5672978 https://reactome.org/PathwayBrowser/#/R-BTA-5672978 RAF phosphorylates MAP2K dimer IEA Bos taurus 9977 R-BTA-9653108 https://reactome.org/PathwayBrowser/#/R-BTA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Bos taurus 9977 R-CEL-5672978 https://reactome.org/PathwayBrowser/#/R-CEL-5672978 RAF phosphorylates MAP2K dimer IEA Caenorhabditis elegans 9977 R-CEL-9653108 https://reactome.org/PathwayBrowser/#/R-CEL-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Caenorhabditis elegans 9977 R-CFA-5672978 https://reactome.org/PathwayBrowser/#/R-CFA-5672978 RAF phosphorylates MAP2K dimer IEA Canis familiaris 9977 R-CFA-9653108 https://reactome.org/PathwayBrowser/#/R-CFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Canis familiaris 9977 R-DME-5672978 https://reactome.org/PathwayBrowser/#/R-DME-5672978 RAF phosphorylates MAP2K dimer IEA Drosophila melanogaster 9977 R-DME-9653108 https://reactome.org/PathwayBrowser/#/R-DME-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Drosophila melanogaster 9977 R-GGA-5672978 https://reactome.org/PathwayBrowser/#/R-GGA-5672978 RAF phosphorylates MAP2K dimer IEA Gallus gallus 9977 R-GGA-9653108 https://reactome.org/PathwayBrowser/#/R-GGA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Gallus gallus 9977 R-HSA-5672978 https://reactome.org/PathwayBrowser/#/R-HSA-5672978 RAF phosphorylates MAP2K dimer TAS Homo sapiens 9977 R-HSA-9653108 https://reactome.org/PathwayBrowser/#/R-HSA-9653108 Raf dimer inhibitors bind RAF heterodimers TAS Homo sapiens 9977 R-MMU-5672978 https://reactome.org/PathwayBrowser/#/R-MMU-5672978 RAF phosphorylates MAP2K dimer IEA Mus musculus 9977 R-MMU-9653108 https://reactome.org/PathwayBrowser/#/R-MMU-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Mus musculus 9977 R-PFA-9653108 https://reactome.org/PathwayBrowser/#/R-PFA-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Plasmodium falciparum 9977 R-RNO-5672978 https://reactome.org/PathwayBrowser/#/R-RNO-5672978 RAF phosphorylates MAP2K dimer IEA Rattus norvegicus 9977 R-RNO-9653108 https://reactome.org/PathwayBrowser/#/R-RNO-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Rattus norvegicus 9977 R-SSC-5672978 https://reactome.org/PathwayBrowser/#/R-SSC-5672978 RAF phosphorylates MAP2K dimer IEA Sus scrofa 9977 R-SSC-9653108 https://reactome.org/PathwayBrowser/#/R-SSC-9653108 Raf dimer inhibitors bind RAF heterodimers IEA Sus scrofa