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         <PDBx:country>UK</PDBx:country>
         <PDBx:journal_abbrev>Nature</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>NATUAS</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0006</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>1476-4687</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>530</PDBx:journal_volume>
         <PDBx:page_first>447</PDBx:page_first>
         <PDBx:page_last>452</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1038/nature16952</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>26886794</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>Structural basis for activity regulation of MLL family methyltransferases.</PDBx:title>
         <PDBx:year>2016</PDBx:year>
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      <PDBx:citation_author citation_id="primary" name="Li, Y." ordinal="1"></PDBx:citation_author>
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      <PDBx:citation_author citation_id="primary" name="Cao, F." ordinal="4"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Liu, Z." ordinal="5"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Li, S." ordinal="6"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Wu, J." ordinal="7"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Hu, C." ordinal="8"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Wang, Y." ordinal="9"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Shuai, J." ordinal="10"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Chen, J." ordinal="11"></PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Cao, L." ordinal="12"></PDBx:citation_author>
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         <PDBx:pdbx_fragment>MLL1 SET domain (UNP RESIDUES 3813-3969)</PDBx:pdbx_fragment>
         <PDBx:pdbx_mutation>N3861I, Q3867L</PDBx:pdbx_mutation>
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      <PDBx:entity_name_com entity_id="1">
         <PDBx:name>Lysine N-methyltransferase 2A,ALL-1,CXXC-type zinc finger protein 7,Myeloid/lymphoid or mixed-lineage leukemia,Myeloid/lymphoid or mixed-lineage leukemia protein 1,Trithorax-like protein,Zinc finger protein HRX</PDBx:name>
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VVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN</PDBx:pdbx_seq_one_letter_code>
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VVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN</PDBx:pdbx_seq_one_letter_code_can>
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         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="10">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="11">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="12">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="13">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="14">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="15">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="16">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="17">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="18">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="19">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="20">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="21">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="22">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="23">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="24">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="25">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="26">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="27">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="28">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="29">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="30">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="31">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="32">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="33">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="34">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="35">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="36">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="37">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="38">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="115">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="116">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="117">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="118">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="119">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="120">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="121">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="122">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="123">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="124">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="125">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="126">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="127">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="128">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="129">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="130">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="131">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="132">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="133">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="134">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="135">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="136">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="137">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="138">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="139">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="140">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="141">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="142">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="143">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="144">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="145">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="146">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="147">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="148">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="149">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="150">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="151">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="152">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="153">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="154">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="155">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="156">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="157">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="158">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
         <PDBx:gene_src_common_name>Human</PDBx:gene_src_common_name>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_beg_seq_num>1</PDBx:pdbx_beg_seq_num>
         <PDBx:pdbx_end_seq_num>158</PDBx:pdbx_end_seq_num>
         <PDBx:pdbx_gene_src_gene>KMT2A, ALL1, CXXC7, HRX, HTRX, MLL, MLL1, TRX1</PDBx:pdbx_gene_src_gene>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>9606</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Homo sapiens</PDBx:pdbx_gene_src_scientific_name>
         <PDBx:pdbx_host_org_ncbi_taxonomy_id>562</PDBx:pdbx_host_org_ncbi_taxonomy_id>
         <PDBx:pdbx_host_org_scientific_name>Escherichia coli</PDBx:pdbx_host_org_scientific_name>
         <PDBx:pdbx_host_org_strain>Rosetta</PDBx:pdbx_host_org_strain>
         <PDBx:pdbx_host_org_vector_type>plasmid</PDBx:pdbx_host_org_vector_type>
         <PDBx:pdbx_seq_type>Biological sequence</PDBx:pdbx_seq_type>
         <PDBx:plasmid_name>pET28b-sumo</PDBx:plasmid_name>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="5F5E"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="5F5E" method="X-RAY DIFFRACTION">
         <PDBx:crystals_number>1</PDBx:crystals_number>
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>2.53</PDBx:density_Matthews>
         <PDBx:density_percent_sol>51.36</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:exptl_crystal_growCategory>
      <PDBx:exptl_crystal_grow crystal_id="1">
         <PDBx:method>VAPOR DIFFUSION, HANGING DROP</PDBx:method>
         <PDBx:pH>7.0</PDBx:pH>
         <PDBx:pdbx_details>35&#37; Tacsimate, pH 7.0</PDBx:pdbx_details>
         <PDBx:temp>277</PDBx:temp>
      </PDBx:exptl_crystal_grow>
   </PDBx:exptl_crystal_growCategory>
   <PDBx:pdbx_audit_revision_detailsCategory>
      <PDBx:pdbx_audit_revision_details data_content_type="Structure model" ordinal="1" revision_ordinal="1">
         <PDBx:provider>repository</PDBx:provider>
         <PDBx:type>Initial release</PDBx:type>
      </PDBx:pdbx_audit_revision_details>
   </PDBx:pdbx_audit_revision_detailsCategory>
   <PDBx:pdbx_audit_revision_groupCategory>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="1" revision_ordinal="2">
         <PDBx:group>Database references</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
   </PDBx:pdbx_audit_revision_groupCategory>
   <PDBx:pdbx_audit_revision_historyCategory>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="1">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>0</PDBx:minor_revision>
         <PDBx:revision_date>2016-02-24</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="2">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>1</PDBx:minor_revision>
         <PDBx:revision_date>2016-04-20</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
   </PDBx:pdbx_audit_revision_historyCategory>
   <PDBx:pdbx_audit_supportCategory>
      <PDBx:pdbx_audit_support ordinal="1">
         <PDBx:country>China</PDBx:country>
         <PDBx:funding_organization>Chinese Academy of Sciences</PDBx:funding_organization>
         <PDBx:grant_number>XDB08010201</PDBx:grant_number>
      </PDBx:pdbx_audit_support>
   </PDBx:pdbx_audit_supportCategory>
   <PDBx:pdbx_database_relatedCategory>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="5F59" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="5F6L" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="5F6K" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
   </PDBx:pdbx_database_relatedCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="5F5E">
         <PDBx:SG_entry>N</PDBx:SG_entry>
         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>PDBJ</PDBx:process_site>
         <PDBx:recvd_initial_deposition_date>2015-12-04</PDBx:recvd_initial_deposition_date>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>ZN</PDBx:comp_id>
         <PDBx:name>ZINC ION</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>SAH</PDBx:comp_id>
         <PDBx:name>S-ADENOSYL-L-HOMOCYSTEINE</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="4">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>ZN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4970</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>ZN</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ZN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4001</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>SAH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4971</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>SAH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SAH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4002</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>94</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4101</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>133</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4102</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>128</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4103</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>111</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4104</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>136</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4105</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>53</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4106</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>90</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4107</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>75</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4108</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>109</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4109</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>118</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4110</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>112</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4111</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>88</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4112</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4113</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>115</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4114</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>63</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4115</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>51</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4116</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4117</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>66</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4118</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>103</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4119</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>13</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4120</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>16</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4121</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>14</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4122</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>69</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4123</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>104</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4124</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>77</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4125</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>34</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4126</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>70</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4127</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>30</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4128</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>89</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4129</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>87</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4130</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4131</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>59</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4132</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4133</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>85</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4134</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>49</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4135</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>44</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4136</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>72</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4137</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4138</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>60</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4139</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>45</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4140</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>41</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4141</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4142</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>50</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4143</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>23</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4144</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>43</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4145</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>20</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4146</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>54</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4147</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>102</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4148</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>138</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4149</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>25</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4150</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>22</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4151</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>24</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4152</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4153</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>116</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4154</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>76</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4155</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>26</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4156</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>110</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4157</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>108</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4158</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4159</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>19</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4160</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4161</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>56</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4162</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>140</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4163</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4164</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>28</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4165</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>117</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4166</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>47</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4167</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>84</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4168</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4169</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>52</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4170</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>18</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4171</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>62</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4172</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>21</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4173</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>73</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4174</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>74</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4175</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>92</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4176</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="77">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>78</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4177</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="78">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>29</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4178</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="79">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>113</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4179</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="80">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>100</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4180</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="81">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>126</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4181</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="82">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>130</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4182</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="83">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>105</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4183</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="84">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4184</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="85">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>80</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4185</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="86">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>27</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4186</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="87">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>135</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4187</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="88">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>12</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4188</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="89">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>39</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4189</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="90">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>91</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4190</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="91">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>32</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4191</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="92">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>35</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4192</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="93">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>42</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4193</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="94">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>58</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4194</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="95">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>99</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4195</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="96">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>17</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4196</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="97">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>79</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4197</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="98">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>107</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4198</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="99">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>81</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4199</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="100">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>46</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4200</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="101">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>48</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4201</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="102">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>114</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4202</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="103">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>141</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4203</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="104">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>132</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4204</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="105">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>86</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4205</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="106">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>71</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4206</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="107">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>64</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4207</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="108">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>38</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4208</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="109">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>97</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4209</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="110">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>33</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4210</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="111">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>127</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4211</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="112">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>83</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4212</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="113">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>121</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4213</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="114">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>124</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4214</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="115">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>67</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4215</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="116">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>40</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4216</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="117">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>106</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4217</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="118">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>15</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4218</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="119">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>31</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4219</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="120">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>123</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4220</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="121">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>82</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4221</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="122">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>57</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4222</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="123">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>55</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4223</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="124">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>101</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4224</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="125">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>61</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4225</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="126">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>65</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4226</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="127">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>134</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4227</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="128">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>142</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4228</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="129">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>125</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4229</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="130">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>137</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4230</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="131">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>68</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4231</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="132">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>131</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4232</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="133">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>37</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4233</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="134">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>98</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4234</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="135">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>129</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4235</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="136">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>95</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4236</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="137">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>122</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4237</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="138">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>93</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4238</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="139">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>96</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4239</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="140">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>120</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4240</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="141">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>139</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4241</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="142">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>119</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4242</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3812</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="2">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3813</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="3">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3814</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3814</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="4">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3815</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3815</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="5">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3816</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3816</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="6">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3817</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3817</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="7">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3818</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3818</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="8">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3819</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3819</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="9">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3820</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3820</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="10">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3821</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3821</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="11">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3822</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3822</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="12">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3823</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3823</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="13">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3824</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3824</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="14">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3825</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3825</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="15">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3826</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3826</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="16">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3827</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3827</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="17">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3828</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3828</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="18">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3829</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3829</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="19">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3830</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3830</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="20">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3831</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3831</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="21">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3832</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3832</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="22">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3833</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3833</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="23">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3834</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3834</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="24">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3835</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3835</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="25">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3836</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3836</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="26">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3837</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3837</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="27">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3838</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3838</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="28">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3839</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3839</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="29">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3840</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3840</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="30">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3841</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3841</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="31">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3842</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3842</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="32">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3843</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3843</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="33">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3844</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3844</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="34">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3845</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3845</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="35">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3846</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3846</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="36">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3847</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3847</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="37">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3848</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3848</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="38">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3849</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3849</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="39">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3850</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3850</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="40">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3851</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3851</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="41">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3852</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3852</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="42">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3853</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3853</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="43">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3854</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3854</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="44">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3855</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3855</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="45">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3856</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3856</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="46">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3857</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3857</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="47">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3858</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3858</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="48">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3859</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3859</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="49">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3860</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3860</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="50">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3861</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3861</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="51">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3862</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3862</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="52">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3863</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3863</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="53">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3864</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3864</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="54">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3865</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3865</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="55">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3866</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3866</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="56">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3867</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3867</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="57">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3868</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3868</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="58">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3869</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3869</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="59">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3870</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3870</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="60">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3871</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3871</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="61">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3872</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3872</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="62">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3873</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3873</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="63">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3874</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3874</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="64">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3875</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3875</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="65">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3876</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3876</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="66">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3877</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3877</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="67">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3878</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3878</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="68">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3879</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3879</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="69">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3880</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3880</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="70">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3881</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3881</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="71">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3882</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3882</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="72">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3883</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3883</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="73">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3884</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3884</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="74">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3885</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3885</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="75">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3886</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3886</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="76">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3887</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3887</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="77">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3888</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3888</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="78">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3889</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3889</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="79">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3890</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3890</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="80">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3891</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3891</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="81">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3892</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3892</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="82">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3893</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3893</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="83">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3894</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3894</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="84">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3895</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3895</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="85">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3896</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3896</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="86">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3897</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3897</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="87">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3898</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3898</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="88">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3899</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3899</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="89">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3900</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3900</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="90">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3901</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3901</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="91">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3902</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3902</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="92">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3903</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3903</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="93">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3904</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3904</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="94">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3905</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3905</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="95">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3906</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3906</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="96">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3907</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3907</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="97">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3908</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3908</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="98">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3909</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3909</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="99">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3910</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3910</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="100">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3911</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3911</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="101">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3912</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3912</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="102">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3913</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3913</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="103">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3914</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3914</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="104">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3915</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3915</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="105">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3916</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3916</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="106">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3917</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3917</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="107">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3918</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3918</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="108">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3919</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3919</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="109">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3920</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3920</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="110">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3921</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3921</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="111">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3922</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3922</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="112">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3923</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3923</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="113">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3924</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3924</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="114">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3925</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3925</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="115">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3926</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3926</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="116">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3927</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3927</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="117">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3928</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3928</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="118">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3929</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3929</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="119">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3930</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3930</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="120">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3931</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3931</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="121">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3932</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3932</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="122">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3933</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3933</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="123">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3934</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3934</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="124">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3935</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3935</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="125">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3936</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3936</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="126">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3937</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3937</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="127">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3938</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3938</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="128">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3939</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3939</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="129">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3940</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3940</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="130">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3941</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3941</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="131">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3942</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3942</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="132">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3943</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3943</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="133">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3944</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3944</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="134">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3945</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3945</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="135">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3946</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="136">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3947</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="137">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3948</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="138">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3949</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="139">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3950</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="140">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3951</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="141">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3952</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="142">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>3953</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="143">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3954</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3954</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="144">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3955</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3955</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="145">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3956</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3956</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="146">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3957</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3957</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="147">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3958</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3958</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="148">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3959</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3959</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="149">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3960</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3960</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="150">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3961</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3961</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="151">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3962</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3962</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="152">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3963</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3963</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="153">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3964</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3964</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="154">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3965</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3965</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="155">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3966</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3966</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="156">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3967</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3967</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="157">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3968</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3968</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="158">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3969</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3969</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_refine_tlsCategory>
      <PDBx:pdbx_refine_tls id="1">
         <PDBx:L11>1.6434</PDBx:L11>
         <PDBx:L12>-1.3597</PDBx:L12>
         <PDBx:L13>1.5188</PDBx:L13>
         <PDBx:L22>1.3364</PDBx:L22>
         <PDBx:L23>-2.2907</PDBx:L23>
         <PDBx:L33>6.4793</PDBx:L33>
         <PDBx:S11>-0.3180</PDBx:S11>
         <PDBx:S12>0.6715</PDBx:S12>
         <PDBx:S13>0.3783</PDBx:S13>
         <PDBx:S21>-1.8989</PDBx:S21>
         <PDBx:S22>0.2644</PDBx:S22>
         <PDBx:S23>2.2333</PDBx:S23>
         <PDBx:S31>-0.8614</PDBx:S31>
         <PDBx:S32>-0.7614</PDBx:S32>
         <PDBx:S33>-0.0993</PDBx:S33>
         <PDBx:T11>1.2840</PDBx:T11>
         <PDBx:T12>0.0080</PDBx:T12>
         <PDBx:T13>-0.5869</PDBx:T13>
         <PDBx:T22>0.5649</PDBx:T22>
         <PDBx:T23>0.0885</PDBx:T23>
         <PDBx:T33>1.1565</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>-15.3151</PDBx:origin_x>
         <PDBx:origin_y>328.7671</PDBx:origin_y>
         <PDBx:origin_z>212.2872</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="2">
         <PDBx:L11>2.8684</PDBx:L11>
         <PDBx:L12>-3.5307</PDBx:L12>
         <PDBx:L13>1.4197</PDBx:L13>
         <PDBx:L22>8.8325</PDBx:L22>
         <PDBx:L23>-0.4670</PDBx:L23>
         <PDBx:L33>4.5199</PDBx:L33>
         <PDBx:S11>-0.2329</PDBx:S11>
         <PDBx:S12>-0.2525</PDBx:S12>
         <PDBx:S13>0.1360</PDBx:S13>
         <PDBx:S21>0.2900</PDBx:S21>
         <PDBx:S22>0.0752</PDBx:S22>
         <PDBx:S23>0.3980</PDBx:S23>
         <PDBx:S31>-0.2499</PDBx:S31>
         <PDBx:S32>-0.3760</PDBx:S32>
         <PDBx:S33>0.1493</PDBx:S33>
         <PDBx:T11>0.3347</PDBx:T11>
         <PDBx:T12>-0.0845</PDBx:T12>
         <PDBx:T13>0.0078</PDBx:T13>
         <PDBx:T22>0.3442</PDBx:T22>
         <PDBx:T23>0.0103</PDBx:T23>
         <PDBx:T33>0.3200</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>-17.8005</PDBx:origin_x>
         <PDBx:origin_y>313.2893</PDBx:origin_y>
         <PDBx:origin_z>219.1648</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="3">
         <PDBx:L11>1.9695</PDBx:L11>
         <PDBx:L12>1.5698</PDBx:L12>
         <PDBx:L13>0.3650</PDBx:L13>
         <PDBx:L22>1.2829</PDBx:L22>
         <PDBx:L23>0.2424</PDBx:L23>
         <PDBx:L33>2.9928</PDBx:L33>
         <PDBx:S11>-0.5514</PDBx:S11>
         <PDBx:S12>0.3715</PDBx:S12>
         <PDBx:S13>-0.1375</PDBx:S13>
         <PDBx:S21>-0.6242</PDBx:S21>
         <PDBx:S22>0.6017</PDBx:S22>
         <PDBx:S23>-0.0558</PDBx:S23>
         <PDBx:S31>-0.1638</PDBx:S31>
         <PDBx:S32>-0.0845</PDBx:S32>
         <PDBx:S33>0.0063</PDBx:S33>
         <PDBx:T11>0.4077</PDBx:T11>
         <PDBx:T12>-0.1365</PDBx:T12>
         <PDBx:T13>-0.0118</PDBx:T13>
         <PDBx:T22>0.2729</PDBx:T22>
         <PDBx:T23>0.0056</PDBx:T23>
         <PDBx:T33>0.2132</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>-11.9610</PDBx:origin_x>
         <PDBx:origin_y>311.9052</PDBx:origin_y>
         <PDBx:origin_z>215.1910</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="4">
         <PDBx:L11>6.7322</PDBx:L11>
         <PDBx:L12>-2.4319</PDBx:L12>
         <PDBx:L13>0.9306</PDBx:L13>
         <PDBx:L22>8.0034</PDBx:L22>
         <PDBx:L23>-4.4220</PDBx:L23>
         <PDBx:L33>8.7927</PDBx:L33>
         <PDBx:S11>-0.3596</PDBx:S11>
         <PDBx:S12>-0.2560</PDBx:S12>
         <PDBx:S13>0.0234</PDBx:S13>
         <PDBx:S21>0.3775</PDBx:S21>
         <PDBx:S22>0.1002</PDBx:S22>
         <PDBx:S23>-0.4897</PDBx:S23>
         <PDBx:S31>-0.0297</PDBx:S31>
         <PDBx:S32>0.6427</PDBx:S32>
         <PDBx:S33>0.2138</PDBx:S33>
         <PDBx:T11>0.3556</PDBx:T11>
         <PDBx:T12>0.0296</PDBx:T12>
         <PDBx:T13>-0.0619</PDBx:T13>
         <PDBx:T22>0.2545</PDBx:T22>
         <PDBx:T23>-0.0749</PDBx:T23>
         <PDBx:T33>0.2328</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>4.9034</PDBx:origin_x>
         <PDBx:origin_y>317.5244</PDBx:origin_y>
         <PDBx:origin_z>232.8142</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="5">
         <PDBx:L11>3.6786</PDBx:L11>
         <PDBx:L12>0.2741</PDBx:L12>
         <PDBx:L13>1.3352</PDBx:L13>
         <PDBx:L22>3.2142</PDBx:L22>
         <PDBx:L23>0.2282</PDBx:L23>
         <PDBx:L33>4.2884</PDBx:L33>
         <PDBx:S11>-0.3923</PDBx:S11>
         <PDBx:S12>0.3829</PDBx:S12>
         <PDBx:S13>-0.2541</PDBx:S13>
         <PDBx:S21>-0.2417</PDBx:S21>
         <PDBx:S22>0.3238</PDBx:S22>
         <PDBx:S23>-0.4369</PDBx:S23>
         <PDBx:S31>0.0428</PDBx:S31>
         <PDBx:S32>0.2201</PDBx:S32>
         <PDBx:S33>0.0551</PDBx:S33>
         <PDBx:T11>0.2697</PDBx:T11>
         <PDBx:T12>-0.0541</PDBx:T12>
         <PDBx:T13>0.0619</PDBx:T13>
         <PDBx:T22>0.1903</PDBx:T22>
         <PDBx:T23>-0.0214</PDBx:T23>
         <PDBx:T33>0.2284</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>-1.9263</PDBx:origin_x>
         <PDBx:origin_y>314.9281</PDBx:origin_y>
         <PDBx:origin_z>222.4577</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="6">
         <PDBx:L11>2.5899</PDBx:L11>
         <PDBx:L12>1.1229</PDBx:L12>
         <PDBx:L13>0.5683</PDBx:L13>
         <PDBx:L22>2.6944</PDBx:L22>
         <PDBx:L23>0.5165</PDBx:L23>
         <PDBx:L33>3.0401</PDBx:L33>
         <PDBx:S11>-0.6958</PDBx:S11>
         <PDBx:S12>0.4861</PDBx:S12>
         <PDBx:S13>-0.2308</PDBx:S13>
         <PDBx:S21>-0.8020</PDBx:S21>
         <PDBx:S22>0.7023</PDBx:S22>
         <PDBx:S23>-0.3564</PDBx:S23>
         <PDBx:S31>-0.2649</PDBx:S31>
         <PDBx:S32>0.4023</PDBx:S32>
         <PDBx:S33>-0.0757</PDBx:S33>
         <PDBx:T11>0.5693</PDBx:T11>
         <PDBx:T12>-0.2745</PDBx:T12>
         <PDBx:T13>0.0496</PDBx:T13>
         <PDBx:T22>0.3602</PDBx:T22>
         <PDBx:T23>-0.0552</PDBx:T23>
         <PDBx:T33>0.2561</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>-6.1576</PDBx:origin_x>
         <PDBx:origin_y>315.9488</PDBx:origin_y>
         <PDBx:origin_z>212.7101</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="7">
         <PDBx:L11>4.8110</PDBx:L11>
         <PDBx:L12>-0.8717</PDBx:L12>
         <PDBx:L13>-2.9611</PDBx:L13>
         <PDBx:L22>2.6291</PDBx:L22>
         <PDBx:L23>-1.1750</PDBx:L23>
         <PDBx:L33>3.5349</PDBx:L33>
         <PDBx:S11>0.5201</PDBx:S11>
         <PDBx:S12>0.0358</PDBx:S12>
         <PDBx:S13>0.1106</PDBx:S13>
         <PDBx:S21>-0.3971</PDBx:S21>
         <PDBx:S22>-0.0753</PDBx:S22>
         <PDBx:S23>-0.3122</PDBx:S23>
         <PDBx:S31>-0.6828</PDBx:S31>
         <PDBx:S32>0.6073</PDBx:S32>
         <PDBx:S33>-2.1253</PDBx:S33>
         <PDBx:T11>0.6366</PDBx:T11>
         <PDBx:T12>-0.1199</PDBx:T12>
         <PDBx:T13>0.3087</PDBx:T13>
         <PDBx:T22>0.7787</PDBx:T22>
         <PDBx:T23>-0.5085</PDBx:T23>
         <PDBx:T33>0.8337</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>4.8827</PDBx:origin_x>
         <PDBx:origin_y>302.7535</PDBx:origin_y>
         <PDBx:origin_z>210.2720</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
   </PDBx:pdbx_refine_tlsCategory>
   <PDBx:pdbx_refine_tls_groupCategory>
      <PDBx:pdbx_refine_tls_group id="1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>0</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>0</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>1</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 3814 through 3822 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>0</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>0</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>2</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 3823 through 3835 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>0</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>0</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>3</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 3836 through 3860 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="4">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>0</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>0</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>4</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 3861 through 3878 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="5">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>0</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>0</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>5</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 3879 through 3912 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="6">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>0</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>0</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>6</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 3913 through 3958 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="7">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>0</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>0</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>7</PDBx:refine_tls_id>
         <PDBx:selection_details>chain &apos;A&apos; and (resid 3959 through 3969 )</PDBx:selection_details>
      </PDBx:pdbx_refine_tls_group>
   </PDBx:pdbx_refine_tls_groupCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_defined_assembly</PDBx:details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C,D" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_conn_angleCategory>
      <PDBx:pdbx_struct_conn_angle id="1">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3909</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>98</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>CYS</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>3957</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>SG</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>CYS</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>146</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>99.4</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="2">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3909</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>98</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>CYS</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>3959</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>SG</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>CYS</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>148</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>82.7</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="3">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3957</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>146</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>CYS</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>3959</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>SG</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>CYS</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>148</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>97.6</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="4">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3909</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>98</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>CYS</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>3964</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>SG</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>CYS</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>153</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>82.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="5">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3957</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>146</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>CYS</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>3964</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>SG</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>CYS</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>153</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>174.2</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="6">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3959</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>148</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>CYS</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>3964</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>SG</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>CYS</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>153</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>87.9</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="7">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3909</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>98</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>4109</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>D</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>126.7</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="8">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3957</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>146</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>4109</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>D</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>119.8</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="9">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3959</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>148</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>4109</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>D</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>121.9</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
      <PDBx:pdbx_struct_conn_angle id="10">
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3964</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>153</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>A</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>HOH</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>4109</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>D</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>O</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>HOH</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id xsi:nil="true" />
         <PDBx:ptnr3_symmetry>1_555</PDBx:ptnr3_symmetry>
         <PDBx:value>55.3</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
   </PDBx:pdbx_struct_conn_angleCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>GLY</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>3832</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>GLY</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>21</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>PHE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>3844</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>PHE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>33</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LEU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>3843</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LEU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>32</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>3940</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>129</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="3" range_id_2="4" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>TYR</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>3942</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>TYR</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>131</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ASN</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>3906</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ASN</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>95</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA2">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>3855</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>44</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ILE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>3928</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ILE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>117</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="AA2">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>HIS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>3925</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>HIS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>114</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ILE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>3918</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ILE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>107</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA3">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ILE</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>3863</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ILE</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>52</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>VAL</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>3892</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>VAL</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>81</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="AA3">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>3893</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>82</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>PHE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>3885</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>PHE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>74</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_unobs_or_zero_occ_atomsCategory>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>SD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3818</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>SD</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>7</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3818</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>7</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3821</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3821</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3821</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3821</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3821</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3821</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3828</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3828</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3828</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3828</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3889</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>78</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3889</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>78</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3889</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>78</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="16">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3910</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="17">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3910</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="18">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3910</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="19">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3910</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="20">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3921</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>110</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="21">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3921</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>110</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="22">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3921</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>110</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="23">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3945</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="24">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3945</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="25">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3945</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="26">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3945</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>134</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="27">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3954</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>143</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="28">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3954</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>143</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="29">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3954</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>143</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="30">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3954</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>143</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="31">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3955</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>144</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="32">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3955</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>144</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="33">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3955</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3963</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3963</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3963</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3963</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>152</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3966</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>155</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3966</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>155</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3966</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>155</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3966</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>155</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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   </PDBx:pdbx_unobs_or_zero_occ_atomsCategory>
   <PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3812</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
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         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3813</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3946</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_seq_id>135</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3947</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>136</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3948</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>137</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3949</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>138</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3950</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>139</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3951</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>140</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3952</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>141</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3953</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>142</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
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      <PDBx:pdbx_validate_close_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
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         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4199</PDBx:auth_seq_id_1>
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         <PDBx:dist>1.89</PDBx:dist>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4102</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>4108</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
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      <PDBx:pdbx_validate_close_contact id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3869</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>4101</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>4221</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
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      <PDBx:pdbx_validate_close_contact id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3871</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>4102</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
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      <PDBx:pdbx_validate_close_contact id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4174</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>4218</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
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      <PDBx:pdbx_validate_close_contact id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3838</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>4103</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
   </PDBx:pdbx_validate_close_contactCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3888</PDBx:auth_seq_id>
         <PDBx:phi>-160.73</PDBx:phi>
         <PDBx:psi>-156.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3966</PDBx:auth_seq_id>
         <PDBx:phi>67.30</PDBx:phi>
         <PDBx:psi>-16.85</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:phasingCategory>
      <PDBx:phasing method="MR"></PDBx:phasing>
   </PDBx:phasingCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="5F5E" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_max>120.810</PDBx:B_iso_max>
         <PDBx:B_iso_mean>45.1431</PDBx:B_iso_mean>
         <PDBx:B_iso_min>19.900</PDBx:B_iso_min>
         <PDBx:ls_R_factor_R_free>0.2363</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.2017</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.2035</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.8020</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>28.0680</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>875</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_R_work>16409</PDBx:ls_number_reflns_R_work>
         <PDBx:ls_number_reflns_obs>17284</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>5.0600</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>99.9700</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_ML>0.1900</PDBx:overall_SU_ML>
         <PDBx:pdbx_R_Free_selection_details>Random selection</PDBx:pdbx_R_Free_selection_details>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>FREE R-VALUE</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>1.360</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>MOLECULAR REPLACEMENT</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_phase_error>24.3300</PDBx:pdbx_overall_phase_error>
         <PDBx:pdbx_solvent_shrinkage_radii>0.9000</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.1100</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_starting_model>2W5Y</PDBx:pdbx_starting_model>
         <PDBx:pdbx_stereochemistry_target_values>ML</PDBx:pdbx_stereochemistry_target_values>
         <PDBx:solvent_model_details>FLAT BULK SOLVENT MODEL</PDBx:solvent_model_details>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="final" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.8020</PDBx:d_res_high>
         <PDBx:d_res_low>28.0680</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>142</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>1325</PDBx:number_atoms_total>
         <PDBx:pdbx_B_iso_mean_ligand>33.19</PDBx:pdbx_B_iso_mean_ligand>
         <PDBx:pdbx_B_iso_mean_solvent>45.77</PDBx:pdbx_B_iso_mean_solvent>
         <PDBx:pdbx_number_atoms_ligand>27</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>1156</PDBx:pdbx_number_atoms_protein>
         <PDBx:pdbx_number_residues_total>148</PDBx:pdbx_number_residues_total>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_bond_d">
         <PDBx:dev_ideal>0.011</PDBx:dev_ideal>
         <PDBx:number>1211</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_angle_d">
         <PDBx:dev_ideal>1.105</PDBx:dev_ideal>
         <PDBx:number>1624</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_chiral_restr">
         <PDBx:dev_ideal>0.051</PDBx:dev_ideal>
         <PDBx:number>174</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_plane_restr">
         <PDBx:dev_ideal>0.004</PDBx:dev_ideal>
         <PDBx:number>206</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_dihedral_angle_d">
         <PDBx:dev_ideal>15.228</PDBx:dev_ideal>
         <PDBx:number>452</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.8018" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2781</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2539</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>1.9147</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>151</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2659</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>2810</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>6</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="1.9147" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2649</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2275</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.0625</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>141</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2698</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>2839</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>6</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.0625" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2543</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2209</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.2699</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>142</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2703</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>2845</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>6</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.2699" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2748</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2259</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.5982</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>163</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2700</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>2863</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>6</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.5982" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2272</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2180</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>3.2726</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>127</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2768</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>2895</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>6</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="3.2726" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2154</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1750</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>28.0709</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>151</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2881</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3032</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>6</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>100.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:d_resolution_high>1.800</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>50.000</PDBx:d_resolution_low>
         <PDBx:entry_id>5F5E</PDBx:entry_id>
         <PDBx:number_obs>17325</PDBx:number_obs>
         <PDBx:pdbx_Rmerge_I_obs>0.090</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_Rpim_I_all>0.031</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.096</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.331</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_av_sigmaI>36.519</PDBx:pdbx_netI_over_av_sigmaI>
         <PDBx:pdbx_netI_over_sigmaI>6.500</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_number_measured_all>166463</PDBx:pdbx_number_measured_all>
         <PDBx:pdbx_redundancy>9.600</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>100.000</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.421</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.800</PDBx:d_res_high>
         <PDBx:d_res_low>1.830</PDBx:d_res_low>
         <PDBx:number_unique_all>854</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.946</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.139</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.444</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.546</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="2">
         <PDBx:Rmerge_I_obs>0.378</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.830</PDBx:d_res_high>
         <PDBx:d_res_low>1.860</PDBx:d_res_low>
         <PDBx:number_unique_all>835</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.945</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.124</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.398</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.574</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>10.100</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="3">
         <PDBx:Rmerge_I_obs>0.343</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.860</PDBx:d_res_high>
         <PDBx:d_res_low>1.900</PDBx:d_res_low>
         <PDBx:number_unique_all>853</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.952</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.113</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.361</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.604</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="4">
         <PDBx:Rmerge_I_obs>0.293</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.900</PDBx:d_res_high>
         <PDBx:d_res_low>1.940</PDBx:d_res_low>
         <PDBx:number_unique_all>857</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.970</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.097</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.309</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.669</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="5">
         <PDBx:Rmerge_I_obs>0.247</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.940</PDBx:d_res_high>
         <PDBx:d_res_low>1.980</PDBx:d_res_low>
         <PDBx:number_unique_all>844</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.970</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.083</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.261</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.742</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.700</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="6">
         <PDBx:Rmerge_I_obs>0.206</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.980</PDBx:d_res_high>
         <PDBx:d_res_low>2.030</PDBx:d_res_low>
         <PDBx:number_unique_all>851</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.981</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.070</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.218</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.815</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.500</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="7">
         <PDBx:Rmerge_I_obs>0.188</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.030</PDBx:d_res_high>
         <PDBx:d_res_low>2.080</PDBx:d_res_low>
         <PDBx:number_unique_all>840</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.980</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.067</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.200</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.914</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>8.800</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="8">
         <PDBx:Rmerge_I_obs>0.177</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.080</PDBx:d_res_high>
         <PDBx:d_res_low>2.130</PDBx:d_res_low>
         <PDBx:number_unique_all>850</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.986</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.058</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.187</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>0.922</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>10.000</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="9">
         <PDBx:Rmerge_I_obs>0.159</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.130</PDBx:d_res_high>
         <PDBx:d_res_low>2.200</PDBx:d_res_low>
         <PDBx:number_unique_all>866</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.986</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.052</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.168</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.056</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>10.100</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="10">
         <PDBx:Rmerge_I_obs>0.150</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.200</PDBx:d_res_high>
         <PDBx:d_res_low>2.270</PDBx:d_res_low>
         <PDBx:number_unique_all>863</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.988</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.050</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.159</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.091</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="11">
         <PDBx:Rmerge_I_obs>0.140</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.270</PDBx:d_res_high>
         <PDBx:d_res_low>2.350</PDBx:d_res_low>
         <PDBx:number_unique_all>848</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.987</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.046</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.147</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.182</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.800</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="12">
         <PDBx:Rmerge_I_obs>0.128</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.350</PDBx:d_res_high>
         <PDBx:d_res_low>2.440</PDBx:d_res_low>
         <PDBx:number_unique_all>858</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.991</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.043</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.135</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.258</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.500</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.900</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="13">
         <PDBx:Rmerge_I_obs>0.121</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.440</PDBx:d_res_high>
         <PDBx:d_res_low>2.550</PDBx:d_res_low>
         <PDBx:number_unique_all>865</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.990</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.042</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.128</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.397</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.000</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.900</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="14">
         <PDBx:Rmerge_I_obs>0.117</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.550</PDBx:d_res_high>
         <PDBx:d_res_low>2.690</PDBx:d_res_low>
         <PDBx:number_unique_all>856</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.991</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.039</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.123</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.512</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>10.000</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="15">
         <PDBx:Rmerge_I_obs>0.107</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.690</PDBx:d_res_high>
         <PDBx:d_res_low>2.860</PDBx:d_res_low>
         <PDBx:number_unique_all>877</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.994</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.035</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.112</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.638</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="16">
         <PDBx:Rmerge_I_obs>0.094</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.860</PDBx:d_res_high>
         <PDBx:d_res_low>3.080</PDBx:d_res_low>
         <PDBx:number_unique_all>868</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.996</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.032</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.099</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>1.780</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.700</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="17">
         <PDBx:Rmerge_I_obs>0.089</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.080</PDBx:d_res_high>
         <PDBx:d_res_low>3.390</PDBx:d_res_low>
         <PDBx:number_unique_all>880</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.995</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.031</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.094</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>2.233</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.000</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.800</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="18">
         <PDBx:Rmerge_I_obs>0.081</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.390</PDBx:d_res_high>
         <PDBx:d_res_low>3.880</PDBx:d_res_low>
         <PDBx:number_unique_all>890</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.996</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.027</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.086</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>2.545</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>9.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="19">
         <PDBx:Rmerge_I_obs>0.074</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.880</PDBx:d_res_high>
         <PDBx:d_res_low>4.880</PDBx:d_res_low>
         <PDBx:number_unique_all>898</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.996</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.026</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.079</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>2.679</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>8.800</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>100.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="20">
         <PDBx:Rmerge_I_obs>0.072</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>4.880</PDBx:d_res_high>
         <PDBx:d_res_low>50.000</PDBx:d_res_low>
         <PDBx:number_unique_all>972</PDBx:number_unique_all>
         <PDBx:pdbx_CC_half>0.996</PDBx:pdbx_CC_half>
         <PDBx:pdbx_Rpim_I_all>0.025</PDBx:pdbx_Rpim_I_all>
         <PDBx:pdbx_Rrim_I_all>0.076</PDBx:pdbx_Rrim_I_all>
         <PDBx:pdbx_chi_squared>2.490</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>8.800</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:name>HKL-2000</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>phasing</PDBx:classification>
         <PDBx:name>PHASER</PDBx:name>
         <PDBx:version>2.5.1</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>PHENIX</PDBx:name>
         <PDBx:version>1.9_1692</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>data extraction</PDBx:classification>
         <PDBx:name>PDB_EXTRACT</PDBx:name>
         <PDBx:version>3.15</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="5">
         <PDBx:classification>data reduction</PDBx:classification>
         <PDBx:name>HKL-2000</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="5F5E">
         <PDBx:pdbx_descriptor>Histone-lysine N-methyltransferase 2A (E.C.2.1.1.43)</PDBx:pdbx_descriptor>
         <PDBx:pdbx_model_details>histone methylation, histone methyltransferase</PDBx:pdbx_model_details>
         <PDBx:title>The Crystal Structure of MLL1 SET domain with N3816I/Q3867L mutation</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="D">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3815</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>4</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3821</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>10</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>7</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3822</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>11</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3830</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>19</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>9</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3867</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>56</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3878</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>67</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>12</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P4">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3900</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>89</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3905</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>94</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_connCategory>
      <PDBx:struct_conn id="metalc1">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.393</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3909</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>98</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc2">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.115</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3957</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>146</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc3">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.502</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3959</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>148</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc4">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.257</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CYS</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>3964</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>SG</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CYS</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>153</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>ZN</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4001</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>ZN</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>ZN</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc5">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.684</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>A</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>ZN</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>4001</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>B</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>ZN</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>ZN</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>A</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>HOH</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>4109</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>D</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>O</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>HOH</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
   </PDBx:struct_connCategory>
   <PDBx:struct_conn_typeCategory>
      <PDBx:struct_conn_type id="metalc">
      </PDBx:struct_conn_type>
   </PDBx:struct_conn_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="5F5E">
         <PDBx:pdbx_keywords>TRANSFERASE</PDBx:pdbx_keywords>
         <PDBx:text>histone methyltransferase, histone methylation, SET domain, TRANSFERASE</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>KMT2A_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>3813</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>Q03164</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>DLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEV
VDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>3813</PDBx:db_align_beg>
         <PDBx:db_align_end>3969</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>5F5E</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>3813</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>3969</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>Q03164</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>2</PDBx:seq_align_beg>
         <PDBx:seq_align_end>158</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>expression tag</PDBx:details>
         <PDBx:mon_id>SER</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>3812</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>5F5E</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q03164</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>1</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="2">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>ASN</PDBx:db_mon_id>
         <PDBx:details>engineered mutation</PDBx:details>
         <PDBx:mon_id>ILE</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>3861</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>5F5E</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q03164</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>3861</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>50</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="3">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>GLN</PDBx:db_mon_id>
         <PDBx:details>engineered mutation</PDBx:details>
         <PDBx:mon_id>LEU</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>3867</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>5F5E</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q03164</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>3867</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>56</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="AA1">
         <PDBx:number_strands>4</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA2">
         <PDBx:number_strands>3</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA3">
         <PDBx:number_strands>3</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="3" range_id_2="4" sheet_id="AA1">
         <PDBx:sense>parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA2">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="AA2">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA3">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="AA3">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3831</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>20</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3835</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>24</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ARG</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3841</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ARG</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>30</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>CYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3845</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>CYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>34</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3939</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>128</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TYR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3942</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TYR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>131</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="4" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3906</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>95</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>HIS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3907</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>HIS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>96</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>MET</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3854</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>MET</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>43</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3857</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>46</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3923</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>112</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3930</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>119</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>CYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3913</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>CYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>102</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3920</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>109</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3861</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>50</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3864</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>53</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3891</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>80</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3894</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>83</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="AA3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>MET</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>3884</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>MET</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>73</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>3886</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>75</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>binding site for residue ZN A 4001</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>ZN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>4001</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>5</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC2">
         <PDBx:details>binding site for residue SAH A 4002</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>SAH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>4002</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>18</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3909</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>98</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3957</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>146</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3959</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>148</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3964</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>153</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>4109</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3838</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>27</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3839</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>28</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3840</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>29</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3841</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>30</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3883</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>72</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3903</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>92</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3904</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3906</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>95</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="14" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3907</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>96</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="15" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3944</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>133</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="16" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3956</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>145</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="17" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3957</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>146</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="18" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>3958</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>147</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="19" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>4122</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="20" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>4135</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="21" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>4149</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="22" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>4169</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="23" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>4187</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>18</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="5F5E">
         <PDBx:Int_Tables_number>154</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 32 2 1</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
