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         <PDBx:journal_abbrev>Biochemistry</PDBx:journal_abbrev>
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         <PDBx:title>NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction.</PDBx:title>
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      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="115">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="116">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="117">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="118">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="119">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="120">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="121">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="122">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="123">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="124">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="125">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="126">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="127">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="128">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="129">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="130">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="131">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="132">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="133">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="134">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="135">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="136">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="137">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="138">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="139">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="140">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="141">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="142">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="143">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="144">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="145">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="146">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="147">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="148">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="149">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="150">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="151">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="152">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="153">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="154">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="155">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="156">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="157">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="158">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="159">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="160">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="161">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="162">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="163">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="164">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="165">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="166">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="167">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="168">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="169">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="170">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="171">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="172">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="173">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="174">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="175">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="176">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="177">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="178">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="179">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="180">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="181">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="182">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="183">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="184">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="185">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="186">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="187">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="188">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="189">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="190">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="191">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
         <PDBx:gene_src_genus>Escherichia</PDBx:gene_src_genus>
         <PDBx:gene_src_strain>XL-1 BLUE</PDBx:gene_src_strain>
         <PDBx:host_org_genus>Escherichia</PDBx:host_org_genus>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>562</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Escherichia coli</PDBx:pdbx_gene_src_scientific_name>
         <PDBx:pdbx_host_org_ncbi_taxonomy_id>562</PDBx:pdbx_host_org_ncbi_taxonomy_id>
         <PDBx:pdbx_host_org_scientific_name>Escherichia coli</PDBx:pdbx_host_org_scientific_name>
         <PDBx:plasmid_name>PQE30</PDBx:plasmid_name>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="2BPR"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="2BPR" method="SOLUTION NMR">
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:pdbx_audit_revision_detailsCategory>
      <PDBx:pdbx_audit_revision_details data_content_type="Structure model" ordinal="1" revision_ordinal="1">
         <PDBx:provider>repository</PDBx:provider>
         <PDBx:type>Initial release</PDBx:type>
      </PDBx:pdbx_audit_revision_details>
   </PDBx:pdbx_audit_revision_detailsCategory>
   <PDBx:pdbx_audit_revision_groupCategory>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="1" revision_ordinal="2">
         <PDBx:group>Version format compliance</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="2" revision_ordinal="3">
         <PDBx:group>Version format compliance</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
   </PDBx:pdbx_audit_revision_groupCategory>
   <PDBx:pdbx_audit_revision_historyCategory>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="1">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>0</PDBx:minor_revision>
         <PDBx:revision_date>1999-03-02</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="2">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>1</PDBx:minor_revision>
         <PDBx:revision_date>2008-03-24</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="3">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>2</PDBx:minor_revision>
         <PDBx:revision_date>2011-07-13</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
   </PDBx:pdbx_audit_revision_historyCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="2BPR">
         <PDBx:SG_entry xsi:nil="true" />
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:recvd_initial_deposition_date>1998-08-11</PDBx:recvd_initial_deposition_date>
         <PDBx:status_code>REL</PDBx:status_code>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_nmr_ensembleCategory>
      <PDBx:pdbx_nmr_ensemble entry_id="2BPR">
         <PDBx:conformer_selection_criteria>TOTAL ENERGY</PDBx:conformer_selection_criteria>
         <PDBx:conformers_calculated_total_number>100</PDBx:conformers_calculated_total_number>
         <PDBx:conformers_submitted_total_number>25</PDBx:conformers_submitted_total_number>
      </PDBx:pdbx_nmr_ensemble>
   </PDBx:pdbx_nmr_ensembleCategory>
   <PDBx:pdbx_nmr_exptlCategory>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="1" solution_id="1">
         <PDBx:type>HNCA</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="2" solution_id="1">
         <PDBx:type>HN(CA)HA</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="3" solution_id="1">
         <PDBx:type>HN(CO)CA</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="4" solution_id="1">
         <PDBx:type>HA(CACO)NH</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="5" solution_id="1">
         <PDBx:type>CP H(C)CCH-TOCSY</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="6" solution_id="1">
         <PDBx:type>CP (H)CCH-TOCSY</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="7" solution_id="1">
         <PDBx:type>CP (H)C(CCACO)NH-TOCSY</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="8" solution_id="1">
         <PDBx:type>15N-RESOLVED NOESY-HSQC</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="9" solution_id="1">
         <PDBx:type>13C RESOLVED NOESY-HMQC</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="10" solution_id="1">
         <PDBx:type>4D 13C RESOLVED HMQC-NOESY-HSQC</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
      <PDBx:pdbx_nmr_exptl conditions_id="1" experiment_id="11" solution_id="1">
         <PDBx:type>HNHA-J</PDBx:type>
      </PDBx:pdbx_nmr_exptl>
   </PDBx:pdbx_nmr_exptlCategory>
   <PDBx:pdbx_nmr_exptl_sample_conditionsCategory>
      <PDBx:pdbx_nmr_exptl_sample_conditions conditions_id="1">
         <PDBx:ionic_strength>50 mM INORGANIC PHOSPHATE</PDBx:ionic_strength>
         <PDBx:pH>7.0</PDBx:pH>
         <PDBx:pressure>1</PDBx:pressure>
         <PDBx:pressure_units>atm</PDBx:pressure_units>
         <PDBx:temperature>298</PDBx:temperature>
         <PDBx:temperature_units>K</PDBx:temperature_units>
      </PDBx:pdbx_nmr_exptl_sample_conditions>
   </PDBx:pdbx_nmr_exptl_sample_conditionsCategory>
   <PDBx:pdbx_nmr_refineCategory>
      <PDBx:pdbx_nmr_refine entry_id="2BPR" software_ordinal="1">
         <PDBx:details>REFINEMENT DETAILS CAN BE FOUND IN THE REFERENCE CITED ABOVE</PDBx:details>
         <PDBx:method>DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS WITH SIMULATED ANNEALING</PDBx:method>
      </PDBx:pdbx_nmr_refine>
   </PDBx:pdbx_nmr_refineCategory>
   <PDBx:pdbx_nmr_sample_detailsCategory>
      <PDBx:pdbx_nmr_sample_details solution_id="1">
         <PDBx:contents>H2O AND D2O</PDBx:contents>
      </PDBx:pdbx_nmr_sample_details>
   </PDBx:pdbx_nmr_sample_detailsCategory>
   <PDBx:pdbx_nmr_softwareCategory>
      <PDBx:pdbx_nmr_software ordinal="1">
         <PDBx:authors>MSI</PDBx:authors>
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>DISCOVER</PDBx:name>
      </PDBx:pdbx_nmr_software>
      <PDBx:pdbx_nmr_software ordinal="2">
         <PDBx:classification>structure solution</PDBx:classification>
         <PDBx:name>BIOSYM</PDBx:name>
      </PDBx:pdbx_nmr_software>
   </PDBx:pdbx_nmr_softwareCategory>
   <PDBx:pdbx_nmr_spectrometerCategory>
      <PDBx:pdbx_nmr_spectrometer spectrometer_id="1">
         <PDBx:field_strength>500</PDBx:field_strength>
         <PDBx:manufacturer>Bruker</PDBx:manufacturer>
         <PDBx:model>AMX500</PDBx:model>
      </PDBx:pdbx_nmr_spectrometer>
      <PDBx:pdbx_nmr_spectrometer spectrometer_id="2">
         <PDBx:field_strength>600</PDBx:field_strength>
         <PDBx:manufacturer>Bruker</PDBx:manufacturer>
         <PDBx:model>AMX600</PDBx:model>
      </PDBx:pdbx_nmr_spectrometer>
   </PDBx:pdbx_nmr_spectrometerCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>371</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="2">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>372</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="3">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>373</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="4">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>374</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="5">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>375</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="6">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>376</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="7">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="8">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="9">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="10">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="11">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>381</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="12">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>382</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="13">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>383</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="14">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>384</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="15">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>385</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="16">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>386</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="17">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>387</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="18">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>388</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="19">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>389</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="20">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>390</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="21">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>391</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="22">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>392</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="23">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>393</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="24">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>394</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="25">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>395</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="26">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="27">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="28">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="29">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="30">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="31">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="32">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="33">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="34">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="35">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="36">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="37">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="38">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="39">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="40">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="41">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="42">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="43">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="44">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="45">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="46">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="47">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="48">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="49">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="50">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="51">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="52">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="53">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="54">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="55">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="56">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="57">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="58">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="59">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="60">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="61">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="62">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="63">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="64">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="65">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="66">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="67">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="68">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="69">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="70">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="71">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="72">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="73">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="74">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="75">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="76">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="77">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="78">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>448</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="79">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="80">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="81">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="82">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="83">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="84">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>454</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="85">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>455</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="86">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>456</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>456</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="87">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>457</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>457</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="88">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>458</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>458</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="89">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>459</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>459</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="90">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>460</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>460</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="91">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>461</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>461</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="92">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>462</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>462</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="93">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>463</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>463</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="94">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>464</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>464</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="95">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>465</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>465</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="96">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>466</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>466</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="97">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>467</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>467</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="98">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>468</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>468</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="99">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>469</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>469</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="100">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>470</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>470</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="101">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>471</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>471</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="102">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>472</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>472</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="103">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>473</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>473</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="104">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>474</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>474</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="105">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>475</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>475</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="106">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>476</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>476</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="107">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>477</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>477</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="108">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>478</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>478</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="109">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>479</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>479</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="110">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>480</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>480</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="111">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>481</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>481</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="112">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>482</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>482</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="113">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>483</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>483</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="114">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>484</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>484</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="115">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>485</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>485</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="116">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>486</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>486</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="117">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>487</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>487</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="118">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>488</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>488</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="119">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>489</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>489</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="120">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>490</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>490</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="121">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>491</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>491</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="122">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>492</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>492</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="123">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>493</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>493</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="124">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>494</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>494</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="125">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>495</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>495</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="126">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>496</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>496</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="127">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>497</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>497</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="128">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>498</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>498</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="129">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>499</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>499</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="130">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>500</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>500</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="131">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>501</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="132">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>502</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="133">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>503</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="134">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>504</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>504</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="135">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>505</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>505</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="136">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>506</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>506</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="137">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>507</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>507</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="138">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>508</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>508</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="139">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>509</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>509</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="140">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>510</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>510</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="141">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>511</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>511</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="142">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>512</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>512</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="143">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>513</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>513</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="144">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>514</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>514</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="145">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>515</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>515</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="146">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>516</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>516</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="147">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>517</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>517</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="148">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>518</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>518</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="149">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>519</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>519</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="150">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>520</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>520</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="151">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>521</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>521</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="152">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>522</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>522</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="153">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>523</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>523</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="154">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>524</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>524</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="155">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>525</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>525</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="156">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>526</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>526</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="157">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>527</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>527</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="158">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>528</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>528</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="159">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>529</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>159</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>529</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="160">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>530</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>160</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>530</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="161">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>531</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>161</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>531</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="162">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>532</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>162</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>532</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="163">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>533</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>163</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>533</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="164">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>534</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>164</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>534</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="165">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>535</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>165</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>535</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="166">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>536</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>166</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>536</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="167">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>537</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>167</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>537</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="168">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>538</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>168</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>538</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="169">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>539</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>169</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>539</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="170">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>540</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>170</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>540</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="171">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>541</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>171</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>541</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="172">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>542</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>172</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>542</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="173">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>543</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>173</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>543</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="174">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>544</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>174</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>544</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="175">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>545</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>175</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>545</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="176">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>546</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>176</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>546</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="177">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>547</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>177</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>547</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="178">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>548</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>178</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>548</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="179">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>549</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>179</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>549</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="180">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>550</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>180</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>550</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="181">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>551</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>181</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>551</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="182">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>552</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>182</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>552</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="183">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>553</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>183</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>553</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="184">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>184</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>554</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="185">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>185</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>555</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="186">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>186</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>556</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="187">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>187</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>557</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="188">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>188</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>558</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="189">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>189</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>559</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="190">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>190</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>560</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="191">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>191</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>561</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ILE</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>401</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ILE</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>31</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>THR</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>409</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>THR</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>39</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="B">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>THR</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>420</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>THR</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>50</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ILE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>478</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ILE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>108</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="B">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>GLU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>473</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>GLU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>103</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LYS</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>489</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LYS</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>119</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="3" range_id_2="4" sheet_id="B">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LEU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>484</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LEU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>114</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ILE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>501</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ILE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>131</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="C">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>436</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>66</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>459</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>89</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="D">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>440</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>70</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>454</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>84</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>371</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>3</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>4</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>376</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>7</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>379</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>380</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>554</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>184</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>555</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>185</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>556</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>186</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>557</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>187</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>558</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>188</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="16">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>559</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>189</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="17">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>190</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="18">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>191</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="19">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>371</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="20">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="21">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>3</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="22">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>4</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="23">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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         <PDBx:label_seq_id>189</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="53">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
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         <PDBx:label_seq_id>190</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>191</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>376</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>7</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:label_seq_id>185</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:label_seq_id>186</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>187</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>558</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>188</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="70">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>559</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>189</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>190</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>191</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
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         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>376</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="79">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="80">
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         <PDBx:label_seq_id>191</PDBx:label_seq_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>371</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="110">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="111">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>3</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="112">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>4</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="113">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>376</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="115">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>7</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>379</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>380</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
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         <PDBx:label_seq_id>10</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>555</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="121">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>186</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>557</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>187</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>558</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>188</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>559</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>189</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>190</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>191</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="130">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="149">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="165">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
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         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="195">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>558</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="196">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>559</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>189</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="197">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>190</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="198">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>191</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>371</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>4</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="203">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="204">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>376</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="205">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>7</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="206">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="207">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>379</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="208">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>380</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="209">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>554</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>184</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="210">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>555</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>185</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="211">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>187</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>558</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>188</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="214">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>559</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>189</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="215">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="220">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="221">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="222">
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         <PDBx:auth_seq_id>376</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="224">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:label_seq_id>9</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>555</PDBx:auth_seq_id>
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         <PDBx:label_seq_id>185</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>557</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>187</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>558</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>188</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="232">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>559</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>189</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="233">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>190</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="234">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>191</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>371</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="237">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>3</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="238">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="239">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="240">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>376</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="241">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
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         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
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         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="250">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
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         <PDBx:label_seq_id>9</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="280">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>380</PDBx:auth_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="281">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
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         <PDBx:label_seq_id>184</PDBx:label_seq_id>
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         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
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         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
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         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
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         <PDBx:label_seq_id>190</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>191</PDBx:label_seq_id>
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         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>371</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:auth_seq_id>372</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>3</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>374</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>375</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>376</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>7</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>379</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>380</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
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         <PDBx:label_seq_id>10</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>554</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>184</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="300">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>555</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>185</PDBx:label_seq_id>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:label_seq_id>189</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="305">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>560</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>190</PDBx:label_seq_id>
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      <PDBx:pdbx_unobs_or_zero_occ_residues id="306">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
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         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>191</PDBx:label_seq_id>
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         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="24">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="25">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>513</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>517</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="26">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HB3</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>471</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>491</PDBx:auth_seq_id_2>
         <PDBx:dist>1.06</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="27">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="28">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="29">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>430</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>467</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="30">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="31">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>393</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>394</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="32">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="33">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.05</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="34">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="35">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>512</PDBx:auth_seq_id_2>
         <PDBx:dist>1.31</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="36">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="37">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="38">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>403</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>409</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="39">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>430</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>467</PDBx:auth_seq_id_2>
         <PDBx:dist>1.10</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="40">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="41">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="42">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="43">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="44">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>471</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>491</PDBx:auth_seq_id_2>
         <PDBx:dist>1.14</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="45">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="46">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="47">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="48">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>471</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>491</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="49">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="50">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="51">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.17</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="52">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>528</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="53">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.32</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="54">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HB3</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>528</PDBx:auth_seq_id_2>
         <PDBx:dist>1.35</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="55">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>528</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="56">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HB3</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>0.92</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="57">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:dist>1.19</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="58">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>397</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="59">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>455</PDBx:auth_seq_id_2>
         <PDBx:dist>1.31</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="60">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>513</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>517</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="61">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>392</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>393</PDBx:auth_seq_id_2>
         <PDBx:dist>1.32</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="62">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>393</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>394</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="63">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="64">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="65">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="66">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.04</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="67">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>498</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="68">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="69">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>498</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="70">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>450</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="71">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.21</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="72">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>444</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>509</PDBx:auth_seq_id_2>
         <PDBx:dist>1.29</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="73">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="74">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="75">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>397</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="76">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>528</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="77">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="78">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HB3</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>528</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="79">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="80">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>528</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="81">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>430</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>467</PDBx:auth_seq_id_2>
         <PDBx:dist>1.15</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="82">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.17</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="83">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="84">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="85">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="86">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>392</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>393</PDBx:auth_seq_id_2>
         <PDBx:dist>1.35</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="87">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="88">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.15</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="89">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="90">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HB3</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>471</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>491</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="91">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="92">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>397</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:dist>0.96</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="93">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HH22</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>467</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>546</PDBx:auth_seq_id_2>
         <PDBx:dist>1.08</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="94">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.19</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="95">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HB3</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>430</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>467</PDBx:auth_seq_id_2>
         <PDBx:dist>1.30</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="96">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="97">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>528</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="98">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="99">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>510</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>514</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="100">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>498</PDBx:auth_seq_id_2>
         <PDBx:dist>0.69</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="101">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.07</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="102">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>397</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:dist>1.15</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="103">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>528</PDBx:auth_seq_id_2>
         <PDBx:dist>1.17</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="104">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>512</PDBx:auth_seq_id_2>
         <PDBx:dist>1.29</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="105">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>498</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="106">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>498</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="107">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>498</PDBx:auth_seq_id_2>
         <PDBx:dist>0.68</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="108">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>392</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>393</PDBx:auth_seq_id_2>
         <PDBx:dist>1.16</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="109">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>393</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>394</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="110">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>498</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="111">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>513</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>517</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="112">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>498</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="113">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>442</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="114">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>433</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>434</PDBx:auth_seq_id_2>
         <PDBx:dist>1.00</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="115">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.28</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="116">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>397</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="117">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>397</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:dist>1.17</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="118">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>HA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>HB2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.29</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="119">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>H</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>524</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>525</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="120">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>H</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>450</PDBx:auth_seq_id_2>
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      </PDBx:pdbx_validate_close_contact>
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         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
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         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
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         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
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         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
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         <PDBx:auth_seq_id_2>470</PDBx:auth_seq_id_2>
         <PDBx:omega>59.39</PDBx:omega>
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      <PDBx:pdbx_validate_peptide_omega id="9">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
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         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
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         <PDBx:auth_seq_id_2>466</PDBx:auth_seq_id_2>
         <PDBx:omega>-124.71</PDBx:omega>
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         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
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         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
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         <PDBx:auth_seq_id_2>466</PDBx:auth_seq_id_2>
         <PDBx:omega>-141.07</PDBx:omega>
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      <PDBx:pdbx_validate_peptide_omega id="11">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
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         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>395</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>396</PDBx:auth_seq_id_2>
         <PDBx:omega>-142.75</PDBx:omega>
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      <PDBx:pdbx_validate_peptide_omega id="13">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
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         <PDBx:auth_seq_id_2>396</PDBx:auth_seq_id_2>
         <PDBx:omega>-140.02</PDBx:omega>
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      <PDBx:pdbx_validate_peptide_omega id="14">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
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         <PDBx:omega>-143.75</PDBx:omega>
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         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>395</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>396</PDBx:auth_seq_id_2>
         <PDBx:omega>-149.56</PDBx:omega>
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         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>395</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>396</PDBx:auth_seq_id_2>
         <PDBx:omega>-144.56</PDBx:omega>
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      <PDBx:pdbx_validate_peptide_omega id="17">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
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         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>395</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>396</PDBx:auth_seq_id_2>
         <PDBx:omega>-143.31</PDBx:omega>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.56</PDBx:angle_deviation>
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         <PDBx:angle_value>122.96</PDBx:angle_value>
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         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-17.59</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>93.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ILE</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>438</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>438</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>438</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>118.95</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.09</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>122.29</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.04</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>123.44</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>456</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>456</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>456</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-22.26</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>88.74</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.52</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>122.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>516</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>516</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="13">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>14.36</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>124.76</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="14">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="15">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>15.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.60</PDBx:angle_target_value>
         <PDBx:angle_value>127.51</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ILE</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>438</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>438</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>438</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="16">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-22.03</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>88.97</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ILE</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>438</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>438</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>438</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="17">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="18">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.52</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>120.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="19">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.11</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.21</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="20">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>17.78</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>127.98</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="21">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.14</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>122.54</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>456</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>456</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>456</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="22">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="23">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="24">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.80</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.30</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="25">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>14.07</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>124.47</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="26">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.95</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.45</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="27">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="28">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.48</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>118.58</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="29">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="30">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-23.07</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>87.93</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="31">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>14.66</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>125.26</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="32">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="33">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="34">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.22</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>122.62</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="35">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="36">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-20.21</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.50</PDBx:angle_target_value>
         <PDBx:angle_value>90.29</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>SER</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>434</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>434</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>434</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="37">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="38">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-10.12</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>100.78</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="39">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>10.42</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>120.52</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="40">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>19.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>130.03</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="41">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.97</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.47</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="42">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-23.39</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>87.61</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="43">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="44">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="45">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.13</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.50</PDBx:angle_target_value>
         <PDBx:angle_value>119.63</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>SER</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>398</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>398</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="46">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.78</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>124.18</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="47">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="48">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="49">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.71</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.40</PDBx:angle_target_value>
         <PDBx:angle_value>124.11</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="50">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-16.44</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>94.56</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="51">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="52">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="53">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.96</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.46</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="54">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.80</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>123.20</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="55">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="56">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.77</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.27</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="57">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.57</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.40</PDBx:angle_target_value>
         <PDBx:angle_value>122.97</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="58">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>10.06</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>120.16</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="59">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.67</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>121.87</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="60">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.98</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.48</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="61">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="62">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.01</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.51</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="63">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>15.68</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>126.08</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="64">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="65">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.96</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.46</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="66">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.23</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>123.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="67">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.94</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.44</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="68">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-21.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>89.13</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="69">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.41</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>123.01</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>534</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>534</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="70">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="71">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="72">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-10.61</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>100.29</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>389</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>389</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>389</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="73">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-18.49</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>92.51</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>391</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>391</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>391</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="74">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-16.13</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>117.20</PDBx:angle_target_value>
         <PDBx:angle_value>101.07</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>N</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>392</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>392</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>393</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>Y</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="75">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-16.38</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>94.62</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>393</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>393</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>393</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="76">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="77">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.78</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.28</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="78">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>121.98</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="79">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>122.10</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="80">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="81">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-22.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>88.11</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="82">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>18.18</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>128.78</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="83">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="84">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="85">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>14.48</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>124.88</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="86">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="87">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.82</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.32</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="88">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.96</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.40</PDBx:angle_target_value>
         <PDBx:angle_value>123.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="89">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>14.20</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>124.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="90">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.84</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.34</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="91">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.35</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>123.95</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="92">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.97</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>122.57</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>534</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>534</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="93">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="94">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.96</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.46</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="95">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>15.09</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>125.49</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="96">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="97">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.15</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>120.05</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>425</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>425</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>425</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="98">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="99">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.40</PDBx:angle_target_value>
         <PDBx:angle_value>124.30</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="100">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.20</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.30</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="101">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="102">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-22.57</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>88.43</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="103">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>14.19</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>124.79</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="104">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="105">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="106">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>15.46</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>125.86</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="107">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="108">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="109">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.17</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>121.27</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="110">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.01</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>122.21</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="111">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="112">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-22.58</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>88.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="113">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.68</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>124.28</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="114">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="115">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="116">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>10.93</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.50</PDBx:angle_target_value>
         <PDBx:angle_value>121.43</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>SER</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>398</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>398</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="117">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="118">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-9.04</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.50</PDBx:angle_target_value>
         <PDBx:angle_value>101.46</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>SER</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>423</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>423</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>423</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="119">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.80</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.30</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="120">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.07</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.17</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="121">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.56</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>123.76</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="122">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-14.04</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>97.46</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>474</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>474</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>474</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="123">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-8.56</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>112.40</PDBx:angle_target_value>
         <PDBx:angle_value>103.84</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>THR</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>475</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>475</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>475</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="124">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="125">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-21.79</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>89.21</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="126">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.06</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>121.66</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>534</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>534</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="127">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="128">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="129">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>15.18</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>125.58</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="130">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="131">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>26.02</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>136.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="132">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.80</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.30</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="133">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.55</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.10</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.10</PDBx:angle_target_value>
         <PDBx:angle_value>133.65</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>O</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="134">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-22.58</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>117.20</PDBx:angle_target_value>
         <PDBx:angle_value>94.62</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>N</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>Y</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="135">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-17.73</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>93.77</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="136">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.02</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="137">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.16</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>122.56</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>MET</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>469</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>469</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>469</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="138">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="139">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="140">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.84</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.34</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="141">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-19.93</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>91.07</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>391</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>391</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>391</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="142">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-17.96</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>117.20</PDBx:angle_target_value>
         <PDBx:angle_value>99.24</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>N</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>392</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>392</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>393</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>Y</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="143">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-16.57</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>94.43</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>393</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>393</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>393</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="144">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>14.74</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>125.14</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="145">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="146">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-10.28</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.50</PDBx:angle_target_value>
         <PDBx:angle_value>100.22</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>SER</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>434</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>434</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>434</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="147">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.74</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.24</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="148">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.64</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.74</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="149">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>15.68</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>125.88</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="150">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="151">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-21.99</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>89.01</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="152">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.80</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>124.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="153">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.94</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.44</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="154">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="155">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="156">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.84</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.34</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="157">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.65</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.40</PDBx:angle_target_value>
         <PDBx:angle_value>123.05</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="158">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.58</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>118.68</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="159">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.52</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>123.72</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="160">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="161">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-17.01</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>93.99</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="162">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>15.62</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>127.12</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>516</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>516</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="163">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.40</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>124.30</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>516</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>516</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="164">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.32</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>123.92</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="165">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="166">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="167">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="168">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-17.70</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>93.30</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>433</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>433</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>433</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="169">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.99</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.49</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="170">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:angle_deviation>17.81</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>128.01</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="171">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="172">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:angle_deviation>10.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>121.46</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>534</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>534</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="173">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="174">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="175">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>18.65</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>129.05</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="176">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="177">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="178">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.74</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>118.84</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="179">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.94</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>124.14</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="180">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="181">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-23.02</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>87.98</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="182">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="183">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="184">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.63</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>124.03</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="185">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="186">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="187">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-9.75</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>101.15</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="188">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.76</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.86</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="189">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-16.47</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>94.53</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="190">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>16.34</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>126.54</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="191">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.94</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.44</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="192">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="193">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="194">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-17.78</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>117.20</PDBx:angle_target_value>
         <PDBx:angle_value>99.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>N</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>392</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>392</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>393</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>Y</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="195">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="196">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="197">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.20</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>121.30</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="198">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>16.22</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>126.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="199">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.44</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>120.34</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>474</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>474</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>474</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="200">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.03</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.53</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="201">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-23.60</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>87.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="202">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.76</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>123.66</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>516</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>516</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>516</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="203">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.11</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>122.71</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="204">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="205">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="206">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.39</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.50</PDBx:angle_target_value>
         <PDBx:angle_value>121.89</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>SER</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>398</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>398</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="207">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="208">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-17.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.50</PDBx:angle_target_value>
         <PDBx:angle_value>92.65</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>SER</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>434</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>434</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>434</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="209">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.04</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.54</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="210">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.99</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.09</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="211">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>16.02</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>126.22</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="212">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.94</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.44</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="213">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-23.82</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>87.18</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="214">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="215">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="216">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="217">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.84</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.34</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="218">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.16</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.26</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="219">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="220">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-22.78</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>88.22</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="221">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="222">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="223">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.65</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.15</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>SER</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>398</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>398</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="224">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="225">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.75</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.25</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="226">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.72</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.82</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="227">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.33</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>122.53</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="228">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.42</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="229">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-22.21</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>88.79</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="230">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="231">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="232">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-21.40</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>117.20</PDBx:angle_target_value>
         <PDBx:angle_value>95.80</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>N</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>392</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>392</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>393</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>Y</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="233">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-9.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>100.20</PDBx:angle_target_value>
         <PDBx:angle_value>90.28</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>SD</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CE</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>MET</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>408</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>408</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>408</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="234">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.69</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>123.09</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="235">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.84</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.34</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="236">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.36</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="237">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.52</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.40</PDBx:angle_target_value>
         <PDBx:angle_value>122.92</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="238">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.74</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>118.84</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="239">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.09</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>123.29</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="240">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.78</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.28</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="241">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.82</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.32</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="242">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.84</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.34</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="243">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="244">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.82</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.32</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="245">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.94</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>122.04</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="246">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.36</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>122.56</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="247">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.94</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.44</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="248">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-23.67</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>87.33</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="249">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.34</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>123.94</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>520</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>520</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="250">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.02</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>121.62</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>534</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>534</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>534</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="251">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.35</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="252">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="253">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.25</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.40</PDBx:angle_target_value>
         <PDBx:angle_value>123.65</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>411</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>411</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>411</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="254">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>422</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>422</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="255">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.88</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>439</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="256">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.84</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.40</PDBx:angle_target_value>
         <PDBx:angle_value>124.24</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>440</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>440</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="257">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.44</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.10</PDBx:angle_target_value>
         <PDBx:angle_value>119.54</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ALA</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>449</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>449</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>449</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="258">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.56</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>121.76</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>454</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>454</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>454</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="259">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.87</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.37</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>485</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>485</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>485</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="260">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-23.79</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>87.21</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>511</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>511</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="261">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.90</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>541</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>541</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="262">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.89</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>120.39</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NE2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>HIS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>544</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
   </PDBx:pdbx_validate_rmsd_angleCategory>
   <PDBx:pdbx_validate_rmsd_bondCategory>
      <PDBx:pdbx_validate_rmsd_bond id="1">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>0.064</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.009</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.354</PDBx:bond_target_value>
         <PDBx:bond_value>1.418</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
      <PDBx:pdbx_validate_rmsd_bond id="2">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>439</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>0.059</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.009</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.354</PDBx:bond_target_value>
         <PDBx:bond_value>1.413</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
   </PDBx:pdbx_validate_rmsd_bondCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:phi>-160.06</PDBx:phi>
         <PDBx:psi>-36.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-166.48</PDBx:phi>
         <PDBx:psi>91.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-140.94</PDBx:phi>
         <PDBx:psi>-48.69</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.45</PDBx:phi>
         <PDBx:psi>-8.44</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>88.42</PDBx:phi>
         <PDBx:psi>136.64</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
         <PDBx:phi>-164.69</PDBx:phi>
         <PDBx:psi>111.59</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>82.80</PDBx:phi>
         <PDBx:psi>18.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-160.26</PDBx:phi>
         <PDBx:psi>119.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-163.62</PDBx:phi>
         <PDBx:psi>97.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-153.98</PDBx:phi>
         <PDBx:psi>-29.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-134.12</PDBx:phi>
         <PDBx:psi>-70.98</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-59.01</PDBx:phi>
         <PDBx:psi>176.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-105.96</PDBx:phi>
         <PDBx:psi>58.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-143.81</PDBx:phi>
         <PDBx:psi>-137.85</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:phi>-137.39</PDBx:phi>
         <PDBx:psi>-130.98</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="16">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>462</PDBx:auth_seq_id>
         <PDBx:phi>-108.73</PDBx:phi>
         <PDBx:psi>59.44</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="17">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:phi>66.73</PDBx:phi>
         <PDBx:psi>140.64</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="18">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>28.95</PDBx:phi>
         <PDBx:psi>123.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="19">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-143.53</PDBx:phi>
         <PDBx:psi>-66.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="20">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:phi>-115.00</PDBx:phi>
         <PDBx:psi>69.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="21">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-95.89</PDBx:phi>
         <PDBx:psi>48.41</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="22">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-153.69</PDBx:phi>
         <PDBx:psi>14.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="23">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-161.05</PDBx:phi>
         <PDBx:psi>94.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="24">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>507</PDBx:auth_seq_id>
         <PDBx:phi>66.49</PDBx:phi>
         <PDBx:psi>151.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="25">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-72.24</PDBx:phi>
         <PDBx:psi>-73.81</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="26">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>90.63</PDBx:phi>
         <PDBx:psi>33.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="27">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>25.03</PDBx:phi>
         <PDBx:psi>91.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="28">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-162.15</PDBx:phi>
         <PDBx:psi>-23.15</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="29">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>63.33</PDBx:phi>
         <PDBx:psi>137.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="30">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-148.60</PDBx:phi>
         <PDBx:psi>-83.69</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="31">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>70.95</PDBx:phi>
         <PDBx:psi>-79.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="32">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:phi>57.92</PDBx:phi>
         <PDBx:psi>75.12</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="33">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:phi>60.69</PDBx:phi>
         <PDBx:psi>76.15</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="34">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-154.95</PDBx:phi>
         <PDBx:psi>-31.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="35">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.45</PDBx:phi>
         <PDBx:psi>-7.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="36">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>86.45</PDBx:phi>
         <PDBx:psi>131.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="37">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
         <PDBx:phi>-161.40</PDBx:phi>
         <PDBx:psi>111.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="38">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>-51.18</PDBx:phi>
         <PDBx:psi>102.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="39">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>85.67</PDBx:phi>
         <PDBx:psi>10.69</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="40">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>427</PDBx:auth_seq_id>
         <PDBx:phi>-164.03</PDBx:phi>
         <PDBx:psi>-166.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="41">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-151.91</PDBx:phi>
         <PDBx:psi>-18.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="42">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-163.48</PDBx:phi>
         <PDBx:psi>-63.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="43">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-167.13</PDBx:phi>
         <PDBx:psi>6.59</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="44">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>435</PDBx:auth_seq_id>
         <PDBx:phi>-165.66</PDBx:phi>
         <PDBx:psi>119.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="45">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>439</PDBx:auth_seq_id>
         <PDBx:phi>-168.38</PDBx:phi>
         <PDBx:psi>58.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="46">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-138.86</PDBx:phi>
         <PDBx:psi>-60.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="47">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-117.26</PDBx:phi>
         <PDBx:psi>52.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="48">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-105.77</PDBx:phi>
         <PDBx:psi>52.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="49">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-141.84</PDBx:phi>
         <PDBx:psi>-134.23</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="50">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:phi>-139.83</PDBx:phi>
         <PDBx:psi>-137.37</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="51">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>65.96</PDBx:phi>
         <PDBx:psi>150.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="52">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-121.55</PDBx:phi>
         <PDBx:psi>-64.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="53">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-90.98</PDBx:phi>
         <PDBx:psi>58.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="54">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>492</PDBx:auth_seq_id>
         <PDBx:phi>-131.15</PDBx:phi>
         <PDBx:psi>-43.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="55">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-151.64</PDBx:phi>
         <PDBx:psi>9.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="56">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-160.73</PDBx:phi>
         <PDBx:psi>90.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="57">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>90.66</PDBx:phi>
         <PDBx:psi>56.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="58">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>-37.07</PDBx:phi>
         <PDBx:psi>153.49</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="59">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>57.81</PDBx:phi>
         <PDBx:psi>90.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="60">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>-163.23</PDBx:phi>
         <PDBx:psi>81.49</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="61">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-164.26</PDBx:phi>
         <PDBx:psi>100.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="62">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>547</PDBx:auth_seq_id>
         <PDBx:phi>-151.35</PDBx:phi>
         <PDBx:psi>-73.18</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="63">
         <PDBx:PDB_model_num>2</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:phi>57.35</PDBx:phi>
         <PDBx:psi>92.77</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="64">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-102.33</PDBx:phi>
         <PDBx:psi>-133.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="65">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-83.55</PDBx:phi>
         <PDBx:psi>-76.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="66">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:phi>-124.65</PDBx:phi>
         <PDBx:psi>-168.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="67">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.28</PDBx:phi>
         <PDBx:psi>-11.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="68">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>84.78</PDBx:phi>
         <PDBx:psi>131.39</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="69">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>85.33</PDBx:phi>
         <PDBx:psi>19.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="70">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-161.68</PDBx:phi>
         <PDBx:psi>114.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="71">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>427</PDBx:auth_seq_id>
         <PDBx:phi>-114.92</PDBx:phi>
         <PDBx:psi>-158.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="72">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-162.60</PDBx:phi>
         <PDBx:psi>41.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="73">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>430</PDBx:auth_seq_id>
         <PDBx:phi>-150.56</PDBx:phi>
         <PDBx:psi>23.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="74">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-161.86</PDBx:phi>
         <PDBx:psi>-38.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="75">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>34.18</PDBx:phi>
         <PDBx:psi>62.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="76">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-159.52</PDBx:phi>
         <PDBx:psi>10.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="77">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>435</PDBx:auth_seq_id>
         <PDBx:phi>-164.02</PDBx:phi>
         <PDBx:psi>118.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="78">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>81.50</PDBx:phi>
         <PDBx:psi>-178.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="79">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-103.30</PDBx:phi>
         <PDBx:psi>51.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="80">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>91.30</PDBx:phi>
         <PDBx:psi>95.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="81">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:phi>65.49</PDBx:phi>
         <PDBx:psi>136.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="82">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-159.38</PDBx:phi>
         <PDBx:psi>73.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="83">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>-54.93</PDBx:phi>
         <PDBx:psi>170.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="84">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-96.24</PDBx:phi>
         <PDBx:psi>35.21</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="85">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-160.98</PDBx:phi>
         <PDBx:psi>89.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="86">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>522</PDBx:auth_seq_id>
         <PDBx:phi>-147.98</PDBx:phi>
         <PDBx:psi>15.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="87">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>523</PDBx:auth_seq_id>
         <PDBx:phi>-66.85</PDBx:phi>
         <PDBx:psi>-79.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="88">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>531</PDBx:auth_seq_id>
         <PDBx:phi>-143.26</PDBx:phi>
         <PDBx:psi>-11.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="89">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>92.71</PDBx:phi>
         <PDBx:psi>35.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="90">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>28.94</PDBx:phi>
         <PDBx:psi>93.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="91">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-162.14</PDBx:phi>
         <PDBx:psi>-22.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="92">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>60.14</PDBx:phi>
         <PDBx:psi>172.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="93">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>60.56</PDBx:phi>
         <PDBx:psi>97.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="94">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>542</PDBx:auth_seq_id>
         <PDBx:phi>-155.71</PDBx:phi>
         <PDBx:psi>82.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="95">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-70.70</PDBx:phi>
         <PDBx:psi>-91.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="96">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-162.33</PDBx:phi>
         <PDBx:psi>110.26</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="97">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>547</PDBx:auth_seq_id>
         <PDBx:phi>-155.50</PDBx:phi>
         <PDBx:psi>-53.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="98">
         <PDBx:PDB_model_num>3</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>550</PDBx:auth_seq_id>
         <PDBx:phi>61.19</PDBx:phi>
         <PDBx:psi>98.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="99">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>60.93</PDBx:phi>
         <PDBx:psi>102.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="100">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-165.21</PDBx:phi>
         <PDBx:psi>94.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="101">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-154.44</PDBx:phi>
         <PDBx:psi>-15.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="102">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>391</PDBx:auth_seq_id>
         <PDBx:phi>-144.81</PDBx:phi>
         <PDBx:psi>16.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="103">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-103.11</PDBx:phi>
         <PDBx:psi>71.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="104">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>396</PDBx:auth_seq_id>
         <PDBx:phi>-95.52</PDBx:phi>
         <PDBx:psi>36.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="105">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.78</PDBx:phi>
         <PDBx:psi>-40.99</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="106">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>112.42</PDBx:phi>
         <PDBx:psi>141.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="107">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
         <PDBx:phi>-163.71</PDBx:phi>
         <PDBx:psi>112.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="108">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>99.90</PDBx:phi>
         <PDBx:psi>-9.95</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="109">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-157.39</PDBx:phi>
         <PDBx:psi>-21.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="110">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-155.81</PDBx:phi>
         <PDBx:psi>22.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="111">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-147.26</PDBx:phi>
         <PDBx:psi>-54.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="112">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-110.52</PDBx:phi>
         <PDBx:psi>66.81</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="113">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-118.93</PDBx:phi>
         <PDBx:psi>-108.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="114">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-125.51</PDBx:phi>
         <PDBx:psi>-128.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="115">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-105.10</PDBx:phi>
         <PDBx:psi>51.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="116">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>464</PDBx:auth_seq_id>
         <PDBx:phi>-119.96</PDBx:phi>
         <PDBx:psi>76.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="117">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-159.39</PDBx:phi>
         <PDBx:psi>84.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="118">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>66.53</PDBx:phi>
         <PDBx:psi>122.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="119">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-127.03</PDBx:phi>
         <PDBx:psi>-63.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="120">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:phi>-113.22</PDBx:phi>
         <PDBx:psi>63.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="121">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-91.99</PDBx:phi>
         <PDBx:psi>56.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="122">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>492</PDBx:auth_seq_id>
         <PDBx:phi>-130.98</PDBx:phi>
         <PDBx:psi>-36.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="123">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-154.08</PDBx:phi>
         <PDBx:psi>7.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="124">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:phi>-178.04</PDBx:phi>
         <PDBx:psi>-77.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="125">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>58.84</PDBx:phi>
         <PDBx:psi>95.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="126">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>504</PDBx:auth_seq_id>
         <PDBx:phi>59.30</PDBx:phi>
         <PDBx:psi>171.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="127">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>512</PDBx:auth_seq_id>
         <PDBx:phi>-65.99</PDBx:phi>
         <PDBx:psi>-71.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="128">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-70.17</PDBx:phi>
         <PDBx:psi>-71.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="129">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>523</PDBx:auth_seq_id>
         <PDBx:phi>-64.64</PDBx:phi>
         <PDBx:psi>-74.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="130">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>91.91</PDBx:phi>
         <PDBx:psi>37.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="131">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>27.79</PDBx:phi>
         <PDBx:psi>92.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="132">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-159.39</PDBx:phi>
         <PDBx:psi>-40.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="133">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>56.69</PDBx:phi>
         <PDBx:psi>80.31</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="134">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-86.91</PDBx:phi>
         <PDBx:psi>-90.73</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="135">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>72.25</PDBx:phi>
         <PDBx:psi>-78.27</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="136">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-164.11</PDBx:phi>
         <PDBx:psi>101.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="137">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:phi>59.38</PDBx:phi>
         <PDBx:psi>94.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="138">
         <PDBx:PDB_model_num>4</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>552</PDBx:auth_seq_id>
         <PDBx:phi>-131.69</PDBx:phi>
         <PDBx:psi>-52.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="139">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-144.15</PDBx:phi>
         <PDBx:psi>-134.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="140">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>389</PDBx:auth_seq_id>
         <PDBx:phi>-116.19</PDBx:phi>
         <PDBx:psi>75.59</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="141">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-100.49</PDBx:phi>
         <PDBx:psi>66.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="142">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.99</PDBx:phi>
         <PDBx:psi>-13.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="143">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>140.01</PDBx:phi>
         <PDBx:psi>127.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="144">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
         <PDBx:phi>-167.72</PDBx:phi>
         <PDBx:psi>113.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="145">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>15.78</PDBx:phi>
         <PDBx:psi>53.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="146">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>86.28</PDBx:phi>
         <PDBx:psi>-5.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="147">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>430</PDBx:auth_seq_id>
         <PDBx:phi>-93.19</PDBx:phi>
         <PDBx:psi>-60.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="148">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-157.51</PDBx:phi>
         <PDBx:psi>-29.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="149">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-105.46</PDBx:phi>
         <PDBx:psi>60.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="150">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>62.93</PDBx:phi>
         <PDBx:psi>160.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="151">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>57.22</PDBx:phi>
         <PDBx:psi>85.23</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="152">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-107.06</PDBx:phi>
         <PDBx:psi>55.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="153">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>171.56</PDBx:phi>
         <PDBx:psi>80.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="154">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-158.20</PDBx:phi>
         <PDBx:psi>82.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="155">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>116.93</PDBx:phi>
         <PDBx:psi>115.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="156">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-121.05</PDBx:phi>
         <PDBx:psi>-66.09</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="157">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>70.50</PDBx:phi>
         <PDBx:psi>34.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="158">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>495</PDBx:auth_seq_id>
         <PDBx:phi>67.56</PDBx:phi>
         <PDBx:psi>-158.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="159">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-166.64</PDBx:phi>
         <PDBx:psi>69.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="160">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>89.17</PDBx:phi>
         <PDBx:psi>56.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="161">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>-16.94</PDBx:phi>
         <PDBx:psi>137.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="162">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-164.54</PDBx:phi>
         <PDBx:psi>76.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="163">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>59.14</PDBx:phi>
         <PDBx:psi>95.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="164">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-170.20</PDBx:phi>
         <PDBx:psi>100.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="165">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-164.58</PDBx:phi>
         <PDBx:psi>94.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="166">
         <PDBx:PDB_model_num>5</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>547</PDBx:auth_seq_id>
         <PDBx:phi>-156.92</PDBx:phi>
         <PDBx:psi>-58.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="167">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-165.09</PDBx:phi>
         <PDBx:psi>97.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="168">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-165.75</PDBx:phi>
         <PDBx:psi>115.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="169">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>56.10</PDBx:phi>
         <PDBx:psi>-154.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="170">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>91.14</PDBx:phi>
         <PDBx:psi>-2.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="171">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>427</PDBx:auth_seq_id>
         <PDBx:phi>-155.09</PDBx:phi>
         <PDBx:psi>-134.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="172">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-98.81</PDBx:phi>
         <PDBx:psi>-61.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="173">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-158.04</PDBx:phi>
         <PDBx:psi>-15.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="174">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-103.91</PDBx:phi>
         <PDBx:psi>54.15</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="175">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-138.34</PDBx:phi>
         <PDBx:psi>-81.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="176">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-63.23</PDBx:phi>
         <PDBx:psi>-174.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="177">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-107.64</PDBx:phi>
         <PDBx:psi>48.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="178">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-179.64</PDBx:phi>
         <PDBx:psi>75.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="179">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-161.07</PDBx:phi>
         <PDBx:psi>116.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="180">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>60.05</PDBx:phi>
         <PDBx:psi>121.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="181">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-146.18</PDBx:phi>
         <PDBx:psi>-48.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="182">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-99.06</PDBx:phi>
         <PDBx:psi>42.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="183">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-152.43</PDBx:phi>
         <PDBx:psi>7.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="184">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:phi>-176.26</PDBx:phi>
         <PDBx:psi>-97.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="185">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>57.47</PDBx:phi>
         <PDBx:psi>95.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="186">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>504</PDBx:auth_seq_id>
         <PDBx:phi>-163.95</PDBx:phi>
         <PDBx:psi>118.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="187">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>533</PDBx:auth_seq_id>
         <PDBx:phi>-79.61</PDBx:phi>
         <PDBx:psi>-75.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="188">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>177.45</PDBx:phi>
         <PDBx:psi>-17.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="189">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>52.47</PDBx:phi>
         <PDBx:psi>102.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="190">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-164.24</PDBx:phi>
         <PDBx:psi>-27.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="191">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-80.27</PDBx:phi>
         <PDBx:psi>-74.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="192">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>78.11</PDBx:phi>
         <PDBx:psi>-26.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="193">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-131.03</PDBx:phi>
         <PDBx:psi>-115.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="194">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-165.12</PDBx:phi>
         <PDBx:psi>55.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="195">
         <PDBx:PDB_model_num>6</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:phi>-161.82</PDBx:phi>
         <PDBx:psi>77.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="196">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>386</PDBx:auth_seq_id>
         <PDBx:phi>74.65</PDBx:phi>
         <PDBx:psi>-35.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="197">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>166.77</PDBx:phi>
         <PDBx:psi>116.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="198">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-146.40</PDBx:phi>
         <PDBx:psi>-87.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="199">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>391</PDBx:auth_seq_id>
         <PDBx:phi>-117.95</PDBx:phi>
         <PDBx:psi>-87.41</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="200">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:phi>35.15</PDBx:phi>
         <PDBx:psi>178.26</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="201">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.06</PDBx:phi>
         <PDBx:psi>113.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="202">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>96.07</PDBx:phi>
         <PDBx:psi>9.27</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="203">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>56.89</PDBx:phi>
         <PDBx:psi>90.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="204">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-73.76</PDBx:phi>
         <PDBx:psi>-89.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="205">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-167.60</PDBx:phi>
         <PDBx:psi>-24.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="206">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-134.14</PDBx:phi>
         <PDBx:psi>-91.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="207">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>171.94</PDBx:phi>
         <PDBx:psi>124.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="208">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>66.49</PDBx:phi>
         <PDBx:psi>138.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="209">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>62.67</PDBx:phi>
         <PDBx:psi>94.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="210">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-108.35</PDBx:phi>
         <PDBx:psi>49.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="211">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-106.04</PDBx:phi>
         <PDBx:psi>44.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="212">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>160.74</PDBx:phi>
         <PDBx:psi>81.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="213">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-159.90</PDBx:phi>
         <PDBx:psi>84.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="214">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>58.11</PDBx:phi>
         <PDBx:psi>105.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="215">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-133.61</PDBx:phi>
         <PDBx:psi>-66.28</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="216">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-97.97</PDBx:phi>
         <PDBx:psi>39.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="217">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-159.71</PDBx:phi>
         <PDBx:psi>14.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="218">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-77.33</PDBx:phi>
         <PDBx:psi>-73.77</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="219">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>531</PDBx:auth_seq_id>
         <PDBx:phi>-149.63</PDBx:phi>
         <PDBx:psi>11.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="220">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>92.40</PDBx:phi>
         <PDBx:psi>31.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="221">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>40.68</PDBx:phi>
         <PDBx:psi>80.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="222">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-166.25</PDBx:phi>
         <PDBx:psi>86.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="223">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-135.07</PDBx:phi>
         <PDBx:psi>-87.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="224">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>72.51</PDBx:phi>
         <PDBx:psi>-78.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="225">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:phi>-55.95</PDBx:phi>
         <PDBx:psi>109.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="226">
         <PDBx:PDB_model_num>7</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:phi>-130.62</PDBx:phi>
         <PDBx:psi>-88.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="227">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-157.07</PDBx:phi>
         <PDBx:psi>36.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="228">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>391</PDBx:auth_seq_id>
         <PDBx:phi>115.56</PDBx:phi>
         <PDBx:psi>91.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="229">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-158.41</PDBx:phi>
         <PDBx:psi>21.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="230">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-159.16</PDBx:phi>
         <PDBx:psi>-57.77</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="231">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>154.85</PDBx:phi>
         <PDBx:psi>132.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="232">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>61.01</PDBx:phi>
         <PDBx:psi>-154.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="233">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-150.50</PDBx:phi>
         <PDBx:psi>-22.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="234">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-105.56</PDBx:phi>
         <PDBx:psi>-76.31</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="235">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>163.32</PDBx:phi>
         <PDBx:psi>125.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="236">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>64.56</PDBx:phi>
         <PDBx:psi>143.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="237">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>60.77</PDBx:phi>
         <PDBx:psi>87.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="238">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-106.66</PDBx:phi>
         <PDBx:psi>43.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="239">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-106.81</PDBx:phi>
         <PDBx:psi>49.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="240">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-171.81</PDBx:phi>
         <PDBx:psi>85.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="241">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>462</PDBx:auth_seq_id>
         <PDBx:phi>-104.60</PDBx:phi>
         <PDBx:psi>70.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="242">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:phi>119.72</PDBx:phi>
         <PDBx:psi>-66.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="243">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>29.02</PDBx:phi>
         <PDBx:psi>123.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="244">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-140.51</PDBx:phi>
         <PDBx:psi>-66.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="245">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:phi>-111.11</PDBx:phi>
         <PDBx:psi>75.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="246">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-100.98</PDBx:phi>
         <PDBx:psi>43.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="247">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-156.87</PDBx:phi>
         <PDBx:psi>12.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="248">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>504</PDBx:auth_seq_id>
         <PDBx:phi>72.45</PDBx:phi>
         <PDBx:psi>-77.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="249">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>64.77</PDBx:phi>
         <PDBx:psi>158.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="250">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>512</PDBx:auth_seq_id>
         <PDBx:phi>-69.97</PDBx:phi>
         <PDBx:psi>-70.31</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="251">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-69.04</PDBx:phi>
         <PDBx:psi>-72.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="252">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>533</PDBx:auth_seq_id>
         <PDBx:phi>-71.36</PDBx:phi>
         <PDBx:psi>-75.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="253">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>171.04</PDBx:phi>
         <PDBx:psi>-7.81</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="254">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>54.97</PDBx:phi>
         <PDBx:psi>101.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="255">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>61.14</PDBx:phi>
         <PDBx:psi>93.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="256">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>-129.63</PDBx:phi>
         <PDBx:psi>-53.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="257">
         <PDBx:PDB_model_num>8</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>76.07</PDBx:phi>
         <PDBx:psi>-66.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="258">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-163.14</PDBx:phi>
         <PDBx:psi>92.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="259">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>389</PDBx:auth_seq_id>
         <PDBx:phi>-104.07</PDBx:phi>
         <PDBx:psi>44.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="260">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-100.23</PDBx:phi>
         <PDBx:psi>71.17</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="261">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-160.43</PDBx:phi>
         <PDBx:psi>-31.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="262">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>158.64</PDBx:phi>
         <PDBx:psi>132.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="263">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
         <PDBx:phi>-165.65</PDBx:phi>
         <PDBx:psi>106.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="264">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>97.06</PDBx:phi>
         <PDBx:psi>-10.27</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="265">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-160.35</PDBx:phi>
         <PDBx:psi>119.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="266">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>427</PDBx:auth_seq_id>
         <PDBx:phi>-157.93</PDBx:phi>
         <PDBx:psi>-158.18</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="267">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>57.23</PDBx:phi>
         <PDBx:psi>87.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="268">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-79.40</PDBx:phi>
         <PDBx:psi>-92.23</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="269">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-160.70</PDBx:phi>
         <PDBx:psi>-33.45</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="270">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-104.75</PDBx:phi>
         <PDBx:psi>57.31</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="271">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-136.27</PDBx:phi>
         <PDBx:psi>-69.05</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="272">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-55.79</PDBx:phi>
         <PDBx:psi>171.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="273">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-107.20</PDBx:phi>
         <PDBx:psi>47.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="274">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-107.95</PDBx:phi>
         <PDBx:psi>49.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="275">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>178.18</PDBx:phi>
         <PDBx:psi>79.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="276">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-159.52</PDBx:phi>
         <PDBx:psi>80.96</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="277">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>58.84</PDBx:phi>
         <PDBx:psi>107.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="278">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-131.85</PDBx:phi>
         <PDBx:psi>-65.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="279">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-94.28</PDBx:phi>
         <PDBx:psi>49.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="280">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-156.30</PDBx:phi>
         <PDBx:psi>8.07</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="281">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-165.37</PDBx:phi>
         <PDBx:psi>71.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="282">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>-157.40</PDBx:phi>
         <PDBx:psi>-52.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="283">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-69.65</PDBx:phi>
         <PDBx:psi>-73.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="284">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>116.49</PDBx:phi>
         <PDBx:psi>21.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="285">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>52.43</PDBx:phi>
         <PDBx:psi>82.77</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="286">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>55.51</PDBx:phi>
         <PDBx:psi>74.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="287">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>-81.58</PDBx:phi>
         <PDBx:psi>-126.27</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="288">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>73.82</PDBx:phi>
         <PDBx:psi>-74.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="289">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>547</PDBx:auth_seq_id>
         <PDBx:phi>-83.00</PDBx:phi>
         <PDBx:psi>-141.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="290">
         <PDBx:PDB_model_num>9</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:phi>-160.10</PDBx:phi>
         <PDBx:psi>116.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="291">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-164.98</PDBx:phi>
         <PDBx:psi>95.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="292">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:phi>-129.25</PDBx:phi>
         <PDBx:psi>-166.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="293">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.24</PDBx:phi>
         <PDBx:psi>-52.98</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="294">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>157.16</PDBx:phi>
         <PDBx:psi>139.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="295">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
         <PDBx:phi>-165.09</PDBx:phi>
         <PDBx:psi>107.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="296">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>32.82</PDBx:phi>
         <PDBx:psi>36.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="297">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>83.95</PDBx:phi>
         <PDBx:psi>24.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="298">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>424</PDBx:auth_seq_id>
         <PDBx:phi>160.36</PDBx:phi>
         <PDBx:psi>157.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="299">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>425</PDBx:auth_seq_id>
         <PDBx:phi>-162.28</PDBx:phi>
         <PDBx:psi>-30.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="300">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>426</PDBx:auth_seq_id>
         <PDBx:phi>71.91</PDBx:phi>
         <PDBx:psi>-79.99</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="301">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>61.52</PDBx:phi>
         <PDBx:psi>84.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="302">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-176.61</PDBx:phi>
         <PDBx:psi>-16.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="303">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-101.34</PDBx:phi>
         <PDBx:psi>60.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="304">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>61.75</PDBx:phi>
         <PDBx:psi>160.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="305">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>58.09</PDBx:phi>
         <PDBx:psi>82.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="306">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-108.57</PDBx:phi>
         <PDBx:psi>42.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="307">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-106.12</PDBx:phi>
         <PDBx:psi>49.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="308">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>178.06</PDBx:phi>
         <PDBx:psi>83.26</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="309">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:phi>64.98</PDBx:phi>
         <PDBx:psi>125.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="310">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>57.60</PDBx:phi>
         <PDBx:psi>123.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="311">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-158.61</PDBx:phi>
         <PDBx:psi>-27.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="312">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>476</PDBx:auth_seq_id>
         <PDBx:phi>-164.01</PDBx:phi>
         <PDBx:psi>-132.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="313">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>495</PDBx:auth_seq_id>
         <PDBx:phi>61.87</PDBx:phi>
         <PDBx:psi>-155.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="314">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>504</PDBx:auth_seq_id>
         <PDBx:phi>60.63</PDBx:phi>
         <PDBx:psi>105.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="315">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>507</PDBx:auth_seq_id>
         <PDBx:phi>-160.65</PDBx:phi>
         <PDBx:psi>114.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="316">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>512</PDBx:auth_seq_id>
         <PDBx:phi>-73.04</PDBx:phi>
         <PDBx:psi>-70.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="317">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-73.34</PDBx:phi>
         <PDBx:psi>-70.09</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="318">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>-177.34</PDBx:phi>
         <PDBx:psi>-10.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="319">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>62.67</PDBx:phi>
         <PDBx:psi>-91.95</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="320">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-160.08</PDBx:phi>
         <PDBx:psi>-70.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="321">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>540</PDBx:auth_seq_id>
         <PDBx:phi>-74.76</PDBx:phi>
         <PDBx:psi>-134.12</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="322">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-94.57</PDBx:phi>
         <PDBx:psi>-115.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="323">
         <PDBx:PDB_model_num>10</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-161.04</PDBx:phi>
         <PDBx:psi>92.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="324">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>58.95</PDBx:phi>
         <PDBx:psi>90.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="325">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-162.51</PDBx:phi>
         <PDBx:psi>69.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="326">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-155.08</PDBx:phi>
         <PDBx:psi>-37.46</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="327">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-100.72</PDBx:phi>
         <PDBx:psi>70.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="328">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.23</PDBx:phi>
         <PDBx:psi>-41.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="329">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>153.39</PDBx:phi>
         <PDBx:psi>124.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="330">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>57.52</PDBx:phi>
         <PDBx:psi>-149.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="331">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>83.86</PDBx:phi>
         <PDBx:psi>9.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="332">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-161.95</PDBx:phi>
         <PDBx:psi>109.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="333">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>427</PDBx:auth_seq_id>
         <PDBx:phi>-151.64</PDBx:phi>
         <PDBx:psi>-148.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="334">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>428</PDBx:auth_seq_id>
         <PDBx:phi>-121.31</PDBx:phi>
         <PDBx:psi>-166.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="335">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>430</PDBx:auth_seq_id>
         <PDBx:phi>-149.49</PDBx:phi>
         <PDBx:psi>-37.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="336">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-72.88</PDBx:phi>
         <PDBx:psi>-85.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="337">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-158.61</PDBx:phi>
         <PDBx:psi>-23.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="338">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>62.64</PDBx:phi>
         <PDBx:psi>164.37</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="339">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>57.27</PDBx:phi>
         <PDBx:psi>87.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="340">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-99.18</PDBx:phi>
         <PDBx:psi>35.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="341">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-103.41</PDBx:phi>
         <PDBx:psi>63.28</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="342">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:phi>86.24</PDBx:phi>
         <PDBx:psi>160.85</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="343">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:phi>-152.81</PDBx:phi>
         <PDBx:psi>-120.95</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="344">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>462</PDBx:auth_seq_id>
         <PDBx:phi>-110.94</PDBx:phi>
         <PDBx:psi>50.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="345">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:phi>64.07</PDBx:phi>
         <PDBx:psi>156.86</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="346">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-158.50</PDBx:phi>
         <PDBx:psi>82.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="347">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>59.42</PDBx:phi>
         <PDBx:psi>127.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="348">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-132.40</PDBx:phi>
         <PDBx:psi>-63.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="349">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-102.67</PDBx:phi>
         <PDBx:psi>49.12</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="350">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-158.02</PDBx:phi>
         <PDBx:psi>11.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="351">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>500</PDBx:auth_seq_id>
         <PDBx:phi>-153.27</PDBx:phi>
         <PDBx:psi>79.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="352">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-71.66</PDBx:phi>
         <PDBx:psi>-71.28</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="353">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>533</PDBx:auth_seq_id>
         <PDBx:phi>-70.60</PDBx:phi>
         <PDBx:psi>-76.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="354">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>163.40</PDBx:phi>
         <PDBx:psi>-10.49</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="355">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>52.55</PDBx:phi>
         <PDBx:psi>91.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="356">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>60.86</PDBx:phi>
         <PDBx:psi>67.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="357">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:phi>64.16</PDBx:phi>
         <PDBx:psi>126.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="358">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-161.84</PDBx:phi>
         <PDBx:psi>96.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="359">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:phi>-161.61</PDBx:phi>
         <PDBx:psi>100.39</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="360">
         <PDBx:PDB_model_num>11</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>552</PDBx:auth_seq_id>
         <PDBx:phi>-158.16</PDBx:phi>
         <PDBx:psi>-55.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="361">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:phi>-160.03</PDBx:phi>
         <PDBx:psi>-50.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="362">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-163.51</PDBx:phi>
         <PDBx:psi>84.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="363">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-155.61</PDBx:phi>
         <PDBx:psi>-30.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="364">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-102.66</PDBx:phi>
         <PDBx:psi>71.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="365">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.49</PDBx:phi>
         <PDBx:psi>-32.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="366">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>112.77</PDBx:phi>
         <PDBx:psi>141.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="367">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>-52.82</PDBx:phi>
         <PDBx:psi>104.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="368">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>93.08</PDBx:phi>
         <PDBx:psi>-13.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="369">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>424</PDBx:auth_seq_id>
         <PDBx:phi>175.19</PDBx:phi>
         <PDBx:psi>156.18</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="370">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>425</PDBx:auth_seq_id>
         <PDBx:phi>-150.24</PDBx:phi>
         <PDBx:psi>-40.85</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="371">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>426</PDBx:auth_seq_id>
         <PDBx:phi>117.10</PDBx:phi>
         <PDBx:psi>-98.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="372">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-102.96</PDBx:phi>
         <PDBx:psi>-82.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="373">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>58.03</PDBx:phi>
         <PDBx:psi>120.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="374">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-160.42</PDBx:phi>
         <PDBx:psi>-87.17</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="375">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-162.11</PDBx:phi>
         <PDBx:psi>-11.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="376">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>84.32</PDBx:phi>
         <PDBx:psi>84.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="377">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-111.05</PDBx:phi>
         <PDBx:psi>-121.12</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="378">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>63.69</PDBx:phi>
         <PDBx:psi>155.45</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="379">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>62.22</PDBx:phi>
         <PDBx:psi>106.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="380">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-171.92</PDBx:phi>
         <PDBx:psi>71.49</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="381">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>460</PDBx:auth_seq_id>
         <PDBx:phi>-147.16</PDBx:phi>
         <PDBx:psi>58.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="382">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-127.14</PDBx:phi>
         <PDBx:psi>-63.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="383">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-86.54</PDBx:phi>
         <PDBx:psi>37.86</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="384">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>495</PDBx:auth_seq_id>
         <PDBx:phi>73.88</PDBx:phi>
         <PDBx:psi>-153.26</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="385">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:phi>-63.86</PDBx:phi>
         <PDBx:psi>-177.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="386">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-155.87</PDBx:phi>
         <PDBx:psi>88.46</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="387">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>-84.04</PDBx:phi>
         <PDBx:psi>-146.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="388">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-70.49</PDBx:phi>
         <PDBx:psi>-73.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="389">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>523</PDBx:auth_seq_id>
         <PDBx:phi>-64.40</PDBx:phi>
         <PDBx:psi>-73.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="390">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>531</PDBx:auth_seq_id>
         <PDBx:phi>-153.16</PDBx:phi>
         <PDBx:psi>4.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="391">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>98.06</PDBx:phi>
         <PDBx:psi>28.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="392">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>40.91</PDBx:phi>
         <PDBx:psi>93.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="393">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-158.20</PDBx:phi>
         <PDBx:psi>-51.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="394">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>55.73</PDBx:phi>
         <PDBx:psi>97.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="395">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-99.03</PDBx:phi>
         <PDBx:psi>-91.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="396">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>78.58</PDBx:phi>
         <PDBx:psi>-36.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="397">
         <PDBx:PDB_model_num>12</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-163.77</PDBx:phi>
         <PDBx:psi>102.44</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="398">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:phi>-160.17</PDBx:phi>
         <PDBx:psi>67.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="399">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-164.29</PDBx:phi>
         <PDBx:psi>69.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="400">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-142.49</PDBx:phi>
         <PDBx:psi>-39.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="401">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:phi>-125.00</PDBx:phi>
         <PDBx:psi>-168.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="402">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.49</PDBx:phi>
         <PDBx:psi>-5.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="403">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>79.63</PDBx:phi>
         <PDBx:psi>129.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="404">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>58.57</PDBx:phi>
         <PDBx:psi>-152.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="405">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-114.28</PDBx:phi>
         <PDBx:psi>-80.45</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="406">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>424</PDBx:auth_seq_id>
         <PDBx:phi>-172.55</PDBx:phi>
         <PDBx:psi>142.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="407">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>425</PDBx:auth_seq_id>
         <PDBx:phi>-164.03</PDBx:phi>
         <PDBx:psi>-29.46</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="408">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>426</PDBx:auth_seq_id>
         <PDBx:phi>80.38</PDBx:phi>
         <PDBx:psi>-90.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="409">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-93.64</PDBx:phi>
         <PDBx:psi>-63.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="410">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-157.45</PDBx:phi>
         <PDBx:psi>-20.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="411">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>439</PDBx:auth_seq_id>
         <PDBx:phi>79.01</PDBx:phi>
         <PDBx:psi>101.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="412">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-116.25</PDBx:phi>
         <PDBx:psi>-77.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="413">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-107.15</PDBx:phi>
         <PDBx:psi>55.86</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="414">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-161.90</PDBx:phi>
         <PDBx:psi>114.86</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="415">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>26.95</PDBx:phi>
         <PDBx:psi>111.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="416">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:phi>-147.41</PDBx:phi>
         <PDBx:psi>-138.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="417">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>471</PDBx:auth_seq_id>
         <PDBx:phi>-107.72</PDBx:phi>
         <PDBx:psi>69.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="418">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-103.52</PDBx:phi>
         <PDBx:psi>42.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="419">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-157.12</PDBx:phi>
         <PDBx:psi>9.17</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="420">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:phi>-57.27</PDBx:phi>
         <PDBx:psi>177.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="421">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-158.63</PDBx:phi>
         <PDBx:psi>89.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="422">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>533</PDBx:auth_seq_id>
         <PDBx:phi>-79.59</PDBx:phi>
         <PDBx:psi>-75.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="423">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>177.03</PDBx:phi>
         <PDBx:psi>-24.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="424">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>81.32</PDBx:phi>
         <PDBx:psi>107.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="425">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>40.48</PDBx:phi>
         <PDBx:psi>93.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="426">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>69.32</PDBx:phi>
         <PDBx:psi>-88.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="427">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-149.47</PDBx:phi>
         <PDBx:psi>-80.46</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="428">
         <PDBx:PDB_model_num>13</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:phi>59.39</PDBx:phi>
         <PDBx:psi>93.39</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="429">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-160.02</PDBx:phi>
         <PDBx:psi>94.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="430">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>391</PDBx:auth_seq_id>
         <PDBx:phi>173.53</PDBx:phi>
         <PDBx:psi>84.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="431">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-162.23</PDBx:phi>
         <PDBx:psi>19.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="432">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.34</PDBx:phi>
         <PDBx:psi>-60.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="433">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>166.24</PDBx:phi>
         <PDBx:psi>146.59</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="434">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>38.31</PDBx:phi>
         <PDBx:psi>31.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="435">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>86.93</PDBx:phi>
         <PDBx:psi>1.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="436">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>426</PDBx:auth_seq_id>
         <PDBx:phi>-136.20</PDBx:phi>
         <PDBx:psi>-157.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="437">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>427</PDBx:auth_seq_id>
         <PDBx:phi>-161.34</PDBx:phi>
         <PDBx:psi>-168.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="438">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-157.66</PDBx:phi>
         <PDBx:psi>-66.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="439">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-161.72</PDBx:phi>
         <PDBx:psi>13.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="440">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-101.04</PDBx:phi>
         <PDBx:psi>60.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="441">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-134.05</PDBx:phi>
         <PDBx:psi>-88.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="442">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-153.60</PDBx:phi>
         <PDBx:psi>-122.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="443">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>59.47</PDBx:phi>
         <PDBx:psi>88.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="444">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-107.12</PDBx:phi>
         <PDBx:psi>42.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="445">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-106.22</PDBx:phi>
         <PDBx:psi>43.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="446">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-168.43</PDBx:phi>
         <PDBx:psi>87.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="447">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:phi>64.01</PDBx:phi>
         <PDBx:psi>125.41</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="448">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>464</PDBx:auth_seq_id>
         <PDBx:phi>-57.39</PDBx:phi>
         <PDBx:psi>109.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="449">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-153.25</PDBx:phi>
         <PDBx:psi>65.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="450">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>52.35</PDBx:phi>
         <PDBx:psi>92.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="451">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-138.48</PDBx:phi>
         <PDBx:psi>-65.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="452">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>495</PDBx:auth_seq_id>
         <PDBx:phi>64.53</PDBx:phi>
         <PDBx:psi>-156.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="453">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:phi>-64.45</PDBx:phi>
         <PDBx:psi>-179.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="454">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-167.55</PDBx:phi>
         <PDBx:psi>66.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="455">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>-84.93</PDBx:phi>
         <PDBx:psi>-149.15</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="456">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>507</PDBx:auth_seq_id>
         <PDBx:phi>-161.83</PDBx:phi>
         <PDBx:psi>113.41</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="457">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>508</PDBx:auth_seq_id>
         <PDBx:phi>-140.48</PDBx:phi>
         <PDBx:psi>-151.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="458">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>512</PDBx:auth_seq_id>
         <PDBx:phi>-72.68</PDBx:phi>
         <PDBx:psi>-73.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="459">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>91.93</PDBx:phi>
         <PDBx:psi>55.28</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="460">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>-12.98</PDBx:phi>
         <PDBx:psi>134.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="461">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>59.17</PDBx:phi>
         <PDBx:psi>-107.09</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="462">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>540</PDBx:auth_seq_id>
         <PDBx:phi>-150.87</PDBx:phi>
         <PDBx:psi>-110.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="463">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>-145.21</PDBx:phi>
         <PDBx:psi>49.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="464">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-96.09</PDBx:phi>
         <PDBx:psi>-114.31</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="465">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-163.79</PDBx:phi>
         <PDBx:psi>59.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="466">
         <PDBx:PDB_model_num>14</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:phi>-160.96</PDBx:phi>
         <PDBx:psi>82.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="467">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-167.35</PDBx:phi>
         <PDBx:psi>99.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="468">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-100.70</PDBx:phi>
         <PDBx:psi>71.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="469">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:phi>-124.73</PDBx:phi>
         <PDBx:psi>-168.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="470">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.99</PDBx:phi>
         <PDBx:psi>-42.23</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="471">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>158.22</PDBx:phi>
         <PDBx:psi>140.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="472">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>55.58</PDBx:phi>
         <PDBx:psi>-154.14</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="473">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>102.61</PDBx:phi>
         <PDBx:psi>-12.14</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="474">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-163.35</PDBx:phi>
         <PDBx:psi>113.59</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="475">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>427</PDBx:auth_seq_id>
         <PDBx:phi>-151.14</PDBx:phi>
         <PDBx:psi>-149.96</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="476">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-162.99</PDBx:phi>
         <PDBx:psi>11.28</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="477">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-169.48</PDBx:phi>
         <PDBx:psi>119.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="478">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-105.91</PDBx:phi>
         <PDBx:psi>-95.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="479">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-172.76</PDBx:phi>
         <PDBx:psi>129.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="480">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>53.50</PDBx:phi>
         <PDBx:psi>152.34</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="481">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>59.93</PDBx:phi>
         <PDBx:psi>89.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="482">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-103.62</PDBx:phi>
         <PDBx:psi>43.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="483">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-107.48</PDBx:phi>
         <PDBx:psi>53.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="484">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>177.23</PDBx:phi>
         <PDBx:psi>105.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="485">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-165.31</PDBx:phi>
         <PDBx:psi>-43.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="486">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>466</PDBx:auth_seq_id>
         <PDBx:phi>-81.81</PDBx:phi>
         <PDBx:psi>45.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="487">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-128.50</PDBx:phi>
         <PDBx:psi>-63.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="488">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>504</PDBx:auth_seq_id>
         <PDBx:phi>56.35</PDBx:phi>
         <PDBx:psi>-153.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="489">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-70.71</PDBx:phi>
         <PDBx:psi>-72.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="490">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>173.12</PDBx:phi>
         <PDBx:psi>-9.14</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="491">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>57.26</PDBx:phi>
         <PDBx:psi>89.46</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="492">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>54.89</PDBx:phi>
         <PDBx:psi>88.73</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="493">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>-151.01</PDBx:phi>
         <PDBx:psi>70.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="494">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>-151.87</PDBx:phi>
         <PDBx:psi>-45.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="495">
         <PDBx:PDB_model_num>15</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:phi>62.04</PDBx:phi>
         <PDBx:psi>150.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="496">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:phi>-131.20</PDBx:phi>
         <PDBx:psi>-62.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="497">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>387</PDBx:auth_seq_id>
         <PDBx:phi>-141.16</PDBx:phi>
         <PDBx:psi>-159.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="498">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-165.72</PDBx:phi>
         <PDBx:psi>99.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="499">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-98.14</PDBx:phi>
         <PDBx:psi>-106.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="500">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>-157.62</PDBx:phi>
         <PDBx:psi>5.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="501">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
         <PDBx:phi>70.93</PDBx:phi>
         <PDBx:psi>108.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="502">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>59.98</PDBx:phi>
         <PDBx:psi>-151.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="503">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-135.72</PDBx:phi>
         <PDBx:psi>-73.17</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="504">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>413</PDBx:auth_seq_id>
         <PDBx:phi>171.11</PDBx:phi>
         <PDBx:psi>-134.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="505">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-163.63</PDBx:phi>
         <PDBx:psi>112.81</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="506">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>428</PDBx:auth_seq_id>
         <PDBx:phi>-89.01</PDBx:phi>
         <PDBx:psi>-133.96</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="507">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-162.48</PDBx:phi>
         <PDBx:psi>-47.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="508">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>60.98</PDBx:phi>
         <PDBx:psi>172.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="509">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-127.53</PDBx:phi>
         <PDBx:psi>-63.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="510">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>58.41</PDBx:phi>
         <PDBx:psi>77.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="511">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-97.83</PDBx:phi>
         <PDBx:psi>57.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="512">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>439</PDBx:auth_seq_id>
         <PDBx:phi>-102.26</PDBx:phi>
         <PDBx:psi>52.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="513">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-105.33</PDBx:phi>
         <PDBx:psi>-149.49</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="514">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>64.52</PDBx:phi>
         <PDBx:psi>135.27</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="515">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>75.38</PDBx:phi>
         <PDBx:psi>85.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="516">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-107.70</PDBx:phi>
         <PDBx:psi>44.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="517">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-102.63</PDBx:phi>
         <PDBx:psi>57.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="518">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-172.07</PDBx:phi>
         <PDBx:psi>72.39</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="519">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:phi>-129.99</PDBx:phi>
         <PDBx:psi>-167.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="520">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-159.44</PDBx:phi>
         <PDBx:psi>79.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="521">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>58.99</PDBx:phi>
         <PDBx:psi>-174.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="522">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-134.35</PDBx:phi>
         <PDBx:psi>-64.31</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="523">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-92.12</PDBx:phi>
         <PDBx:psi>57.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="524">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>492</PDBx:auth_seq_id>
         <PDBx:phi>-131.58</PDBx:phi>
         <PDBx:psi>-49.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="525">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-145.52</PDBx:phi>
         <PDBx:psi>10.37</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="526">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-164.76</PDBx:phi>
         <PDBx:psi>93.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="527">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>97.62</PDBx:phi>
         <PDBx:psi>57.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="528">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>-39.39</PDBx:phi>
         <PDBx:psi>153.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="529">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-156.29</PDBx:phi>
         <PDBx:psi>-23.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="530">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>63.39</PDBx:phi>
         <PDBx:psi>133.27</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="531">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>60.20</PDBx:phi>
         <PDBx:psi>97.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="532">
         <PDBx:PDB_model_num>16</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>552</PDBx:auth_seq_id>
         <PDBx:phi>-158.19</PDBx:phi>
         <PDBx:psi>84.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="533">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:phi>-129.72</PDBx:phi>
         <PDBx:psi>-55.05</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="534">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-163.52</PDBx:phi>
         <PDBx:psi>81.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="535">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-155.34</PDBx:phi>
         <PDBx:psi>-32.26</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="536">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-100.94</PDBx:phi>
         <PDBx:psi>69.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="537">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.82</PDBx:phi>
         <PDBx:psi>5.09</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="538">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>78.13</PDBx:phi>
         <PDBx:psi>129.44</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="539">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-104.09</PDBx:phi>
         <PDBx:psi>-66.45</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="540">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>84.21</PDBx:phi>
         <PDBx:psi>17.59</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="541">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-96.08</PDBx:phi>
         <PDBx:psi>-72.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="542">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>430</PDBx:auth_seq_id>
         <PDBx:phi>-149.15</PDBx:phi>
         <PDBx:psi>-49.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="543">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>-173.36</PDBx:phi>
         <PDBx:psi>117.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="544">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-154.32</PDBx:phi>
         <PDBx:psi>-86.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="545">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-168.03</PDBx:phi>
         <PDBx:psi>-24.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="546">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>94.65</PDBx:phi>
         <PDBx:psi>95.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="547">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>435</PDBx:auth_seq_id>
         <PDBx:phi>-164.22</PDBx:phi>
         <PDBx:psi>119.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="548">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>64.25</PDBx:phi>
         <PDBx:psi>-171.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="549">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>-78.15</PDBx:phi>
         <PDBx:psi>-169.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="550">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>63.50</PDBx:phi>
         <PDBx:psi>103.18</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="551">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-100.08</PDBx:phi>
         <PDBx:psi>42.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="552">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-105.09</PDBx:phi>
         <PDBx:psi>45.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="553">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-178.78</PDBx:phi>
         <PDBx:psi>45.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="554">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:phi>-152.26</PDBx:phi>
         <PDBx:psi>-117.39</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="555">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-157.02</PDBx:phi>
         <PDBx:psi>-38.37</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="556">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>72.33</PDBx:phi>
         <PDBx:psi>32.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="557">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>495</PDBx:auth_seq_id>
         <PDBx:phi>68.21</PDBx:phi>
         <PDBx:psi>-156.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="558">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>504</PDBx:auth_seq_id>
         <PDBx:phi>63.08</PDBx:phi>
         <PDBx:psi>136.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="559">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>-82.52</PDBx:phi>
         <PDBx:psi>-146.23</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="560">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-72.42</PDBx:phi>
         <PDBx:psi>-71.86</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="561">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>523</PDBx:auth_seq_id>
         <PDBx:phi>-62.58</PDBx:phi>
         <PDBx:psi>-70.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="562">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>91.07</PDBx:phi>
         <PDBx:psi>35.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="563">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>30.57</PDBx:phi>
         <PDBx:psi>98.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="564">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-160.23</PDBx:phi>
         <PDBx:psi>-32.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="565">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>58.11</PDBx:phi>
         <PDBx:psi>107.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="566">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-131.29</PDBx:phi>
         <PDBx:psi>-90.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="567">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>70.56</PDBx:phi>
         <PDBx:psi>-81.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="568">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-154.46</PDBx:phi>
         <PDBx:psi>89.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="569">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-155.70</PDBx:phi>
         <PDBx:psi>65.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="570">
         <PDBx:PDB_model_num>17</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:phi>-161.68</PDBx:phi>
         <PDBx:psi>79.27</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="571">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:phi>-77.20</PDBx:phi>
         <PDBx:psi>-122.23</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="572">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>389</PDBx:auth_seq_id>
         <PDBx:phi>-106.02</PDBx:phi>
         <PDBx:psi>74.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="573">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-148.46</PDBx:phi>
         <PDBx:psi>-20.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="574">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-105.85</PDBx:phi>
         <PDBx:psi>70.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="575">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>396</PDBx:auth_seq_id>
         <PDBx:phi>-101.35</PDBx:phi>
         <PDBx:psi>48.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="576">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-164.18</PDBx:phi>
         <PDBx:psi>-41.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="577">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>110.06</PDBx:phi>
         <PDBx:psi>130.96</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="578">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>-33.37</PDBx:phi>
         <PDBx:psi>93.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="579">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>94.17</PDBx:phi>
         <PDBx:psi>-5.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="580">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>427</PDBx:auth_seq_id>
         <PDBx:phi>-158.88</PDBx:phi>
         <PDBx:psi>-157.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="581">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>57.60</PDBx:phi>
         <PDBx:psi>87.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="582">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-160.05</PDBx:phi>
         <PDBx:psi>-40.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="583">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-112.09</PDBx:phi>
         <PDBx:psi>56.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="584">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>62.07</PDBx:phi>
         <PDBx:psi>161.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="585">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>57.49</PDBx:phi>
         <PDBx:psi>77.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="586">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-103.85</PDBx:phi>
         <PDBx:psi>55.15</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="587">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-159.19</PDBx:phi>
         <PDBx:psi>85.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="588">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>58.56</PDBx:phi>
         <PDBx:psi>110.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="589">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-134.05</PDBx:phi>
         <PDBx:psi>-72.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="590">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-94.48</PDBx:phi>
         <PDBx:psi>47.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="591">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-151.86</PDBx:phi>
         <PDBx:psi>12.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="592">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>533</PDBx:auth_seq_id>
         <PDBx:phi>-69.82</PDBx:phi>
         <PDBx:psi>-76.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="593">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>-175.12</PDBx:phi>
         <PDBx:psi>-27.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="594">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>46.32</PDBx:phi>
         <PDBx:psi>93.73</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="595">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-162.98</PDBx:phi>
         <PDBx:psi>-27.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="596">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>55.63</PDBx:phi>
         <PDBx:psi>73.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="597">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-91.35</PDBx:phi>
         <PDBx:psi>-75.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="598">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>71.68</PDBx:phi>
         <PDBx:psi>-80.86</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="599">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-90.14</PDBx:phi>
         <PDBx:psi>-109.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="600">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-164.13</PDBx:phi>
         <PDBx:psi>111.91</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="601">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:phi>-155.46</PDBx:phi>
         <PDBx:psi>71.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="602">
         <PDBx:PDB_model_num>18</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:phi>-161.84</PDBx:phi>
         <PDBx:psi>94.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="603">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:phi>-160.06</PDBx:phi>
         <PDBx:psi>-57.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="604">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-166.41</PDBx:phi>
         <PDBx:psi>94.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="605">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>391</PDBx:auth_seq_id>
         <PDBx:phi>-114.75</PDBx:phi>
         <PDBx:psi>54.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="606">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-142.87</PDBx:phi>
         <PDBx:psi>29.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="607">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-156.77</PDBx:phi>
         <PDBx:psi>-54.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="608">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>146.72</PDBx:phi>
         <PDBx:psi>128.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="609">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>30.00</PDBx:phi>
         <PDBx:psi>43.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="610">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-106.70</PDBx:phi>
         <PDBx:psi>-74.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="611">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>92.01</PDBx:phi>
         <PDBx:psi>-4.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="612">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>424</PDBx:auth_seq_id>
         <PDBx:phi>-173.70</PDBx:phi>
         <PDBx:psi>126.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="613">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>425</PDBx:auth_seq_id>
         <PDBx:phi>-164.46</PDBx:phi>
         <PDBx:psi>-33.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="614">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>426</PDBx:auth_seq_id>
         <PDBx:phi>86.05</PDBx:phi>
         <PDBx:psi>-87.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="615">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-153.64</PDBx:phi>
         <PDBx:psi>87.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="616">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-152.43</PDBx:phi>
         <PDBx:psi>-21.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="617">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>435</PDBx:auth_seq_id>
         <PDBx:phi>-166.41</PDBx:phi>
         <PDBx:psi>118.46</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="618">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>102.20</PDBx:phi>
         <PDBx:psi>155.95</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="619">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>-67.65</PDBx:phi>
         <PDBx:psi>-178.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="620">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>62.19</PDBx:phi>
         <PDBx:psi>88.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="621">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>448</PDBx:auth_seq_id>
         <PDBx:phi>-69.98</PDBx:phi>
         <PDBx:psi>94.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="622">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-108.09</PDBx:phi>
         <PDBx:psi>47.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="623">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-169.73</PDBx:phi>
         <PDBx:psi>92.21</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="624">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>43.08</PDBx:phi>
         <PDBx:psi>113.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="625">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-99.20</PDBx:phi>
         <PDBx:psi>-67.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="626">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:phi>-116.73</PDBx:phi>
         <PDBx:psi>65.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="627">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>476</PDBx:auth_seq_id>
         <PDBx:phi>-163.93</PDBx:phi>
         <PDBx:psi>-130.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="628">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-89.23</PDBx:phi>
         <PDBx:psi>48.14</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="629">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-159.06</PDBx:phi>
         <PDBx:psi>77.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="630">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>504</PDBx:auth_seq_id>
         <PDBx:phi>-164.48</PDBx:phi>
         <PDBx:psi>110.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="631">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>-162.66</PDBx:phi>
         <PDBx:psi>-56.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="632">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-71.18</PDBx:phi>
         <PDBx:psi>-73.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="633">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>533</PDBx:auth_seq_id>
         <PDBx:phi>-69.20</PDBx:phi>
         <PDBx:psi>-79.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="634">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>167.36</PDBx:phi>
         <PDBx:psi>-25.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="635">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>68.44</PDBx:phi>
         <PDBx:psi>120.98</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="636">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-158.78</PDBx:phi>
         <PDBx:psi>-53.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="637">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>55.90</PDBx:phi>
         <PDBx:psi>90.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="638">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-130.92</PDBx:phi>
         <PDBx:psi>-86.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="639">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-149.12</PDBx:phi>
         <PDBx:psi>-105.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="640">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-167.37</PDBx:phi>
         <PDBx:psi>111.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="641">
         <PDBx:PDB_model_num>19</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>547</PDBx:auth_seq_id>
         <PDBx:phi>-155.02</PDBx:phi>
         <PDBx:psi>48.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="642">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-165.93</PDBx:phi>
         <PDBx:psi>97.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="643">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-138.98</PDBx:phi>
         <PDBx:psi>-48.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="644">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-101.89</PDBx:phi>
         <PDBx:psi>69.85</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="645">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.30</PDBx:phi>
         <PDBx:psi>-47.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="646">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>127.15</PDBx:phi>
         <PDBx:psi>122.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="647">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>87.38</PDBx:phi>
         <PDBx:psi>12.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="648">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-161.52</PDBx:phi>
         <PDBx:psi>113.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="649">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>426</PDBx:auth_seq_id>
         <PDBx:phi>-130.42</PDBx:phi>
         <PDBx:psi>-158.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="650">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-142.13</PDBx:phi>
         <PDBx:psi>-4.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="651">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>430</PDBx:auth_seq_id>
         <PDBx:phi>-148.42</PDBx:phi>
         <PDBx:psi>-15.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="652">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>-162.44</PDBx:phi>
         <PDBx:psi>117.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="653">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-151.01</PDBx:phi>
         <PDBx:psi>-45.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="654">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-113.48</PDBx:phi>
         <PDBx:psi>-89.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="655">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-159.63</PDBx:phi>
         <PDBx:psi>-117.17</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="656">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>60.84</PDBx:phi>
         <PDBx:psi>99.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="657">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-107.53</PDBx:phi>
         <PDBx:psi>43.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="658">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-102.23</PDBx:phi>
         <PDBx:psi>66.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="659">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-173.24</PDBx:phi>
         <PDBx:psi>55.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="660">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:phi>-125.94</PDBx:phi>
         <PDBx:psi>-159.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="661">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-159.69</PDBx:phi>
         <PDBx:psi>88.28</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="662">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>63.49</PDBx:phi>
         <PDBx:psi>150.59</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="663">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-93.13</PDBx:phi>
         <PDBx:psi>55.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="664">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>492</PDBx:auth_seq_id>
         <PDBx:phi>-131.25</PDBx:phi>
         <PDBx:psi>-42.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="665">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-159.02</PDBx:phi>
         <PDBx:psi>61.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="666">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-71.62</PDBx:phi>
         <PDBx:psi>-71.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="667">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>523</PDBx:auth_seq_id>
         <PDBx:phi>-64.56</PDBx:phi>
         <PDBx:psi>-75.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="668">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>85.60</PDBx:phi>
         <PDBx:psi>40.05</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="669">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>21.89</PDBx:phi>
         <PDBx:psi>114.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="670">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>71.71</PDBx:phi>
         <PDBx:psi>97.18</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="671">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>59.17</PDBx:phi>
         <PDBx:psi>135.14</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="672">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-150.61</PDBx:phi>
         <PDBx:psi>-37.63</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="673">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-88.24</PDBx:phi>
         <PDBx:psi>-108.64</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="674">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:phi>-161.40</PDBx:phi>
         <PDBx:psi>85.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="675">
         <PDBx:PDB_model_num>20</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:phi>59.09</PDBx:phi>
         <PDBx:psi>93.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="676">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:phi>58.94</PDBx:phi>
         <PDBx:psi>71.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="677">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>386</PDBx:auth_seq_id>
         <PDBx:phi>-124.57</PDBx:phi>
         <PDBx:psi>-59.96</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="678">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-151.40</PDBx:phi>
         <PDBx:psi>-38.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="679">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.97</PDBx:phi>
         <PDBx:psi>-11.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="680">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>95.09</PDBx:phi>
         <PDBx:psi>121.26</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="681">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>-47.31</PDBx:phi>
         <PDBx:psi>103.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="682">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-97.42</PDBx:phi>
         <PDBx:psi>-63.41</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="683">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>87.35</PDBx:phi>
         <PDBx:psi>2.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="684">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-161.31</PDBx:phi>
         <PDBx:psi>-6.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="685">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>430</PDBx:auth_seq_id>
         <PDBx:phi>-93.38</PDBx:phi>
         <PDBx:psi>-95.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="686">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>431</PDBx:auth_seq_id>
         <PDBx:phi>162.08</PDBx:phi>
         <PDBx:psi>74.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="687">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-162.22</PDBx:phi>
         <PDBx:psi>-65.78</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="688">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-103.96</PDBx:phi>
         <PDBx:psi>-92.73</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="689">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>171.55</PDBx:phi>
         <PDBx:psi>134.60</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="690">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>84.56</PDBx:phi>
         <PDBx:psi>-85.99</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="691">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-101.76</PDBx:phi>
         <PDBx:psi>50.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="692">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>167.83</PDBx:phi>
         <PDBx:psi>78.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="693">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-162.96</PDBx:phi>
         <PDBx:psi>87.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="694">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>-70.54</PDBx:phi>
         <PDBx:psi>-169.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="695">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:phi>-90.86</PDBx:phi>
         <PDBx:psi>53.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="696">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-156.59</PDBx:phi>
         <PDBx:psi>73.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="697">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>-82.72</PDBx:phi>
         <PDBx:psi>-137.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="698">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>512</PDBx:auth_seq_id>
         <PDBx:phi>-68.42</PDBx:phi>
         <PDBx:psi>-71.72</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="699">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-71.33</PDBx:phi>
         <PDBx:psi>-72.44</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="700">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>523</PDBx:auth_seq_id>
         <PDBx:phi>-64.05</PDBx:phi>
         <PDBx:psi>-76.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="701">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>95.20</PDBx:phi>
         <PDBx:psi>34.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="702">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>47.14</PDBx:phi>
         <PDBx:psi>98.09</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="703">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>59.18</PDBx:phi>
         <PDBx:psi>90.18</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="704">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>76.26</PDBx:phi>
         <PDBx:psi>-70.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="705">
         <PDBx:PDB_model_num>21</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:phi>-157.35</PDBx:phi>
         <PDBx:psi>76.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="706">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:phi>-160.06</PDBx:phi>
         <PDBx:psi>-58.69</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="707">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-164.85</PDBx:phi>
         <PDBx:psi>77.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="708">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-145.06</PDBx:phi>
         <PDBx:psi>-42.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="709">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-100.14</PDBx:phi>
         <PDBx:psi>68.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="710">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.02</PDBx:phi>
         <PDBx:psi>-17.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="711">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>106.95</PDBx:phi>
         <PDBx:psi>148.44</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="712">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>85.71</PDBx:phi>
         <PDBx:psi>15.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="713">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-165.79</PDBx:phi>
         <PDBx:psi>112.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="714">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-165.13</PDBx:phi>
         <PDBx:psi>-19.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="715">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-103.87</PDBx:phi>
         <PDBx:psi>-91.43</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="716">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-169.41</PDBx:phi>
         <PDBx:psi>116.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="717">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>446</PDBx:auth_seq_id>
         <PDBx:phi>64.00</PDBx:phi>
         <PDBx:psi>152.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="718">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>63.75</PDBx:phi>
         <PDBx:psi>110.52</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="719">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-105.96</PDBx:phi>
         <PDBx:psi>45.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="720">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-106.92</PDBx:phi>
         <PDBx:psi>47.25</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="721">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>454</PDBx:auth_seq_id>
         <PDBx:phi>-141.83</PDBx:phi>
         <PDBx:psi>35.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="722">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-177.21</PDBx:phi>
         <PDBx:psi>78.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="723">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>43.78</PDBx:phi>
         <PDBx:psi>112.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="724">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-140.03</PDBx:phi>
         <PDBx:psi>-64.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="725">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:phi>-116.19</PDBx:phi>
         <PDBx:psi>67.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="726">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>72.10</PDBx:phi>
         <PDBx:psi>31.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="727">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>495</PDBx:auth_seq_id>
         <PDBx:phi>60.07</PDBx:phi>
         <PDBx:psi>-159.76</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="728">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>502</PDBx:auth_seq_id>
         <PDBx:phi>-66.92</PDBx:phi>
         <PDBx:psi>-175.03</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="729">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-164.31</PDBx:phi>
         <PDBx:psi>92.08</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="730">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-73.02</PDBx:phi>
         <PDBx:psi>-72.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="731">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>523</PDBx:auth_seq_id>
         <PDBx:phi>-65.41</PDBx:phi>
         <PDBx:psi>-79.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="732">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>91.88</PDBx:phi>
         <PDBx:psi>36.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="733">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>25.14</PDBx:phi>
         <PDBx:psi>103.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="734">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-153.15</PDBx:phi>
         <PDBx:psi>-92.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="735">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>78.46</PDBx:phi>
         <PDBx:psi>-47.46</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="736">
         <PDBx:PDB_model_num>22</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-89.65</PDBx:phi>
         <PDBx:psi>-106.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="737">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>391</PDBx:auth_seq_id>
         <PDBx:phi>-109.39</PDBx:phi>
         <PDBx:psi>49.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="738">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-165.62</PDBx:phi>
         <PDBx:psi>20.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="739">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-157.07</PDBx:phi>
         <PDBx:psi>-50.20</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="740">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>123.90</PDBx:phi>
         <PDBx:psi>143.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="741">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>399</PDBx:auth_seq_id>
         <PDBx:phi>-161.96</PDBx:phi>
         <PDBx:psi>116.53</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="742">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>-33.82</PDBx:phi>
         <PDBx:psi>91.74</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="743">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>411</PDBx:auth_seq_id>
         <PDBx:phi>-101.42</PDBx:phi>
         <PDBx:psi>-72.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="744">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>71.83</PDBx:phi>
         <PDBx:psi>30.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="745">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-162.58</PDBx:phi>
         <PDBx:psi>118.30</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="746">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>428</PDBx:auth_seq_id>
         <PDBx:phi>-109.70</PDBx:phi>
         <PDBx:psi>-161.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="747">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>430</PDBx:auth_seq_id>
         <PDBx:phi>-149.31</PDBx:phi>
         <PDBx:psi>-22.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="748">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-92.47</PDBx:phi>
         <PDBx:psi>59.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="749">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-158.56</PDBx:phi>
         <PDBx:psi>-35.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="750">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-107.65</PDBx:phi>
         <PDBx:psi>55.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="751">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>81.84</PDBx:phi>
         <PDBx:psi>169.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="752">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-104.86</PDBx:phi>
         <PDBx:psi>49.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="753">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>-178.13</PDBx:phi>
         <PDBx:psi>77.01</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="754">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-157.81</PDBx:phi>
         <PDBx:psi>83.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="755">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>57.64</PDBx:phi>
         <PDBx:psi>98.59</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="756">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>-133.63</PDBx:phi>
         <PDBx:psi>-67.12</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="757">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-154.70</PDBx:phi>
         <PDBx:psi>13.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="758">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-165.97</PDBx:phi>
         <PDBx:psi>95.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="759">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>533</PDBx:auth_seq_id>
         <PDBx:phi>-70.01</PDBx:phi>
         <PDBx:psi>-75.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="760">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>-175.34</PDBx:phi>
         <PDBx:psi>-21.95</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="761">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-162.39</PDBx:phi>
         <PDBx:psi>86.86</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="762">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-88.25</PDBx:phi>
         <PDBx:psi>-71.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="763">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>69.27</PDBx:phi>
         <PDBx:psi>-83.95</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="764">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-88.73</PDBx:phi>
         <PDBx:psi>-109.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="765">
         <PDBx:PDB_model_num>23</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:phi>-166.10</PDBx:phi>
         <PDBx:psi>110.16</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="766">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-173.77</PDBx:phi>
         <PDBx:psi>97.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="767">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-83.78</PDBx:phi>
         <PDBx:psi>-84.51</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="768">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>392</PDBx:auth_seq_id>
         <PDBx:phi>-161.48</PDBx:phi>
         <PDBx:psi>109.57</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="769">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-118.28</PDBx:phi>
         <PDBx:psi>61.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="770">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:phi>-129.45</PDBx:phi>
         <PDBx:psi>-168.58</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="771">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-163.06</PDBx:phi>
         <PDBx:psi>-29.11</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="772">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>148.22</PDBx:phi>
         <PDBx:psi>128.99</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="773">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>-49.34</PDBx:phi>
         <PDBx:psi>97.90</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="774">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>80.48</PDBx:phi>
         <PDBx:psi>1.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="775">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:phi>-162.67</PDBx:phi>
         <PDBx:psi>114.19</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="776">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>428</PDBx:auth_seq_id>
         <PDBx:phi>-84.93</PDBx:phi>
         <PDBx:psi>-146.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="777">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>429</PDBx:auth_seq_id>
         <PDBx:phi>-164.25</PDBx:phi>
         <PDBx:psi>-41.28</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="778">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>432</PDBx:auth_seq_id>
         <PDBx:phi>-146.60</PDBx:phi>
         <PDBx:psi>-97.80</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="779">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-172.98</PDBx:phi>
         <PDBx:psi>3.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="780">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>66.00</PDBx:phi>
         <PDBx:psi>79.95</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="781">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-104.33</PDBx:phi>
         <PDBx:psi>-78.61</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="782">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>445</PDBx:auth_seq_id>
         <PDBx:phi>-148.55</PDBx:phi>
         <PDBx:psi>-134.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="783">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>447</PDBx:auth_seq_id>
         <PDBx:phi>60.56</PDBx:phi>
         <PDBx:psi>88.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="784">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-112.79</PDBx:phi>
         <PDBx:psi>50.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="785">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>457</PDBx:auth_seq_id>
         <PDBx:phi>90.19</PDBx:phi>
         <PDBx:psi>164.55</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="786">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>458</PDBx:auth_seq_id>
         <PDBx:phi>-150.76</PDBx:phi>
         <PDBx:psi>-108.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="787">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:phi>66.20</PDBx:phi>
         <PDBx:psi>124.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="788">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>71.24</PDBx:phi>
         <PDBx:psi>128.04</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="789">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-96.72</PDBx:phi>
         <PDBx:psi>55.84</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="790">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>492</PDBx:auth_seq_id>
         <PDBx:phi>-130.32</PDBx:phi>
         <PDBx:psi>-35.05</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="791">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-150.75</PDBx:phi>
         <PDBx:psi>3.93</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="792">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-152.68</PDBx:phi>
         <PDBx:psi>-115.10</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="793">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>504</PDBx:auth_seq_id>
         <PDBx:phi>57.54</PDBx:phi>
         <PDBx:psi>99.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="794">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>-152.80</PDBx:phi>
         <PDBx:psi>-151.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="795">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>512</PDBx:auth_seq_id>
         <PDBx:phi>-66.37</PDBx:phi>
         <PDBx:psi>-71.69</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="796">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>113.14</PDBx:phi>
         <PDBx:psi>13.14</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="797">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>51.00</PDBx:phi>
         <PDBx:psi>116.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="798">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>60.84</PDBx:phi>
         <PDBx:psi>94.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="799">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>541</PDBx:auth_seq_id>
         <PDBx:phi>78.44</PDBx:phi>
         <PDBx:psi>-52.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="800">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>543</PDBx:auth_seq_id>
         <PDBx:phi>-163.45</PDBx:phi>
         <PDBx:psi>101.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="801">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>550</PDBx:auth_seq_id>
         <PDBx:phi>60.27</PDBx:phi>
         <PDBx:psi>94.28</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="802">
         <PDBx:PDB_model_num>24</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>552</PDBx:auth_seq_id>
         <PDBx:phi>-81.66</PDBx:phi>
         <PDBx:psi>-95.70</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="803">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:phi>-163.31</PDBx:phi>
         <PDBx:psi>81.33</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="804">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:phi>-154.98</PDBx:phi>
         <PDBx:psi>-33.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="805">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:phi>-100.78</PDBx:phi>
         <PDBx:psi>69.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="806">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:phi>-162.60</PDBx:phi>
         <PDBx:psi>-1.14</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="807">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>398</PDBx:auth_seq_id>
         <PDBx:phi>89.67</PDBx:phi>
         <PDBx:psi>136.83</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="808">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:phi>50.19</PDBx:phi>
         <PDBx:psi>-160.41</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="809">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>415</PDBx:auth_seq_id>
         <PDBx:phi>85.88</PDBx:phi>
         <PDBx:psi>12.77</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="810">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>433</PDBx:auth_seq_id>
         <PDBx:phi>-171.59</PDBx:phi>
         <PDBx:psi>81.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="811">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>434</PDBx:auth_seq_id>
         <PDBx:phi>-145.75</PDBx:phi>
         <PDBx:psi>-20.44</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="812">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>438</PDBx:auth_seq_id>
         <PDBx:phi>-103.91</PDBx:phi>
         <PDBx:psi>59.97</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="813">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>444</PDBx:auth_seq_id>
         <PDBx:phi>-110.83</PDBx:phi>
         <PDBx:psi>-79.94</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="814">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>450</PDBx:auth_seq_id>
         <PDBx:phi>-108.85</PDBx:phi>
         <PDBx:psi>48.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="815">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>451</PDBx:auth_seq_id>
         <PDBx:phi>-108.31</PDBx:phi>
         <PDBx:psi>47.48</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="816">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>456</PDBx:auth_seq_id>
         <PDBx:phi>177.72</PDBx:phi>
         <PDBx:psi>75.99</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="817">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:phi>-160.84</PDBx:phi>
         <PDBx:psi>117.23</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="818">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>467</PDBx:auth_seq_id>
         <PDBx:phi>30.58</PDBx:phi>
         <PDBx:psi>120.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="819">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:phi>-99.03</PDBx:phi>
         <PDBx:psi>42.45</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="820">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:phi>-159.18</PDBx:phi>
         <PDBx:psi>14.38</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="821">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>503</PDBx:auth_seq_id>
         <PDBx:phi>-150.15</PDBx:phi>
         <PDBx:psi>87.75</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="822">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>505</PDBx:auth_seq_id>
         <PDBx:phi>-89.73</PDBx:phi>
         <PDBx:psi>-143.68</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="823">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>517</PDBx:auth_seq_id>
         <PDBx:phi>-71.54</PDBx:phi>
         <PDBx:psi>-71.62</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="824">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>522</PDBx:auth_seq_id>
         <PDBx:phi>-147.22</PDBx:phi>
         <PDBx:psi>17.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="825">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>523</PDBx:auth_seq_id>
         <PDBx:phi>-61.30</PDBx:phi>
         <PDBx:psi>-81.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="826">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>534</PDBx:auth_seq_id>
         <PDBx:phi>75.64</PDBx:phi>
         <PDBx:psi>57.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="827">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>535</PDBx:auth_seq_id>
         <PDBx:phi>-15.35</PDBx:phi>
         <PDBx:psi>147.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="828">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>71.98</PDBx:phi>
         <PDBx:psi>79.02</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="829">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:phi>59.30</PDBx:phi>
         <PDBx:psi>95.79</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="830">
         <PDBx:PDB_model_num>25</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:phi>-77.40</PDBx:phi>
         <PDBx:psi>-72.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="2BPR">
         <PDBx:pdbx_descriptor>DNAK</PDBx:pdbx_descriptor>
         <PDBx:title>NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>Y</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1">
      </PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>509</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>139</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>532</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>162</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>24</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="2BPR">
         <PDBx:pdbx_keywords>MOLECULAR CHAPERONE</PDBx:pdbx_keywords>
         <PDBx:text>MOLECULAR CHAPERONE, HSP70, PEPTIDE BINDING, PROTEIN FOLDING</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_mon_prot_cisCategory>
      <PDBx:struct_mon_prot_cis pdbx_id="1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.70</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>3.57</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>2</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.04</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="4">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>95</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>2</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>466</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>96</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-7.60</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="5">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>2</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>13.73</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="6">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>3</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>6.65</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="7">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>4</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>4.34</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="8">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>4</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>7.03</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="9">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>4</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>1.39</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="10">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>5</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>7.11</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="11">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>5</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>0.52</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="12">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>6</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>4.98</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="13">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>6</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>9.73</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="14">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>6</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.85</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="15">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>7</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.71</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="16">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>7</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.61</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="17">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>7</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-0.95</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="18">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>8</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>5.14</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="19">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>8</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>1.18</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="20">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>8</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-0.84</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="21">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>9</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>5.93</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="22">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>9</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>9.01</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="23">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>9</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-0.99</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="24">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>10</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>5.31</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="25">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>11</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.58</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="26">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>11</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-3.68</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="27">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>12</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>9.09</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="28">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>12</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-19.92</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="29">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>95</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>12</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>466</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>96</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-16.03</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="30">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>12</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>3.60</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="31">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>13</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>9.10</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="32">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>13</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>4.48</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="33">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>14</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>0.05</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="34">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>14</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>6.83</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="35">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>15</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>5.82</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="36">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>15</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>3.72</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="37">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>15</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>0.32</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="38">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>16</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-0.76</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="39">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>16</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-0.27</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="40">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>16</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>11.43</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="41">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>17</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>7.83</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="42">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>17</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-21.78</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="43">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>95</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>17</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>466</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>96</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-8.95</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="44">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>18</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>7.40</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="45">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>18</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>0.87</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="46">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>18</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>1.42</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="47">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>19</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-0.67</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="48">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>19</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>10.33</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="49">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>19</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>5.74</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="50">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>20</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>5.83</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="51">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>20</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>10.20</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="52">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>20</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>13.30</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="53">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>21</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>10.12</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="54">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>21</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-4.16</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="55">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>22</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.83</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="56">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>22</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.49</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="57">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>22</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>3.11</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="58">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>23</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>5.40</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="59">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>23</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>3.33</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="60">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>24</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>8.84</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="61">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>465</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>95</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>24</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>466</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>96</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-9.74</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="62">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>24</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>470</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>100</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>6.28</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="63">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>48</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>25</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>419</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>49</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>9.61</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="64">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>463</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>25</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>464</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>94</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>11.49</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
   </PDBx:struct_mon_prot_cisCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>DNAK_ECOLI</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>1</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P0A6Y8</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>GKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEE
VQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIA
GLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLV
EEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLK
VALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGI
ETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDAD
GILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADD
KTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDDDVVDAEFEEVKDKK</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>379</PDBx:db_align_beg>
         <PDBx:db_align_end>560</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>2BPR</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>380</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>561</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P0A6Y8</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>10</PDBx:seq_align_beg>
         <PDBx:seq_align_end>191</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>VAL</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>SER</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>381</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>2BPR</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P0A6Y8</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>380</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>11</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="2">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>LEU</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>ILE</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>382</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>2BPR</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P0A6Y8</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>381</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>12</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="3">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>THR</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>GLU</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>383</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>2BPR</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P0A6Y8</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>382</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>13</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="4">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>ASP</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>ARG</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>385</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>2BPR</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P0A6Y8</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>384</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>15</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="A">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="B">
         <PDBx:number_strands>4</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="C">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="D">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="3" range_id_2="4" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="C">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="D">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>401</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>31</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>THR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>403</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>THR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>33</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>407</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>37</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>THR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>409</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>THR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>39</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="B">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>420</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>50</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>PHE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>426</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>PHE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>56</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="B">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>472</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>102</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>478</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>108</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="B">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>483</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>113</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>490</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>120</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="4" sheet_id="B">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>496</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>126</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>502</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>132</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="C">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ALA</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>435</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ALA</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>65</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>438</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>68</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="C">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PHE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>457</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PHE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>87</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>460</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>90</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="D">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>440</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>70</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>442</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>72</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="D">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>452</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>82</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>454</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>84</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="2BPR">
         <PDBx:Int_Tables_number>1</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 1</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
