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      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>CO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>101</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>CO</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>101</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>102</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>102</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DG" seq_id="1">
         <PDBx:auth_mon_id>G</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DC" seq_id="2">
         <PDBx:auth_mon_id>C</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DC</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DA" seq_id="3">
         <PDBx:auth_mon_id>A</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DT" seq_id="4">
         <PDBx:auth_mon_id>T</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DT</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DG" seq_id="5">
         <PDBx:auth_mon_id>G</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>5</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DC" seq_id="6">
         <PDBx:auth_mon_id>C</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DC</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>6</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="DT" seq_id="7">
         <PDBx:auth_mon_id>T</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DT</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>7</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>X</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_defined_assembly</PDBx:details>
         <PDBx:oligomeric_count>4</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>tetrameric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C" oper_expression="1,2,3,4"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_conn_angleCategory>
      <PDBx:pdbx_struct_conn_angle id="1">
         <PDBx:ptnr1_auth_asym_id>X</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>DG</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>1</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>A</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>N7</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>DG</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id>1</PDBx:ptnr1_label_seq_id>
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>X</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>CO</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>101</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>B</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>CO</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>CO</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id xsi:nil="true" />
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
         <PDBx:ptnr3_auth_asym_id>X</PDBx:ptnr3_auth_asym_id>
         <PDBx:ptnr3_auth_comp_id>DG</PDBx:ptnr3_auth_comp_id>
         <PDBx:ptnr3_auth_seq_id>5</PDBx:ptnr3_auth_seq_id>
         <PDBx:ptnr3_label_asym_id>A</PDBx:ptnr3_label_asym_id>
         <PDBx:ptnr3_label_atom_id>N7</PDBx:ptnr3_label_atom_id>
         <PDBx:ptnr3_label_comp_id>DG</PDBx:ptnr3_label_comp_id>
         <PDBx:ptnr3_label_seq_id>5</PDBx:ptnr3_label_seq_id>
         <PDBx:ptnr3_symmetry>12_555</PDBx:ptnr3_symmetry>
         <PDBx:value>176.3</PDBx:value>
      </PDBx:pdbx_struct_conn_angle>
   </PDBx:pdbx_struct_conn_angleCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="2">
         <PDBx:matrix11>-1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>-1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>4_555</PDBx:name>
         <PDBx:symmetry_operation>-x,-y,z</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="3">
         <PDBx:matrix11>-0.5000000000</PDBx:matrix11>
         <PDBx:matrix12>-0.8660254038</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>-0.8660254038</PDBx:matrix21>
         <PDBx:matrix22>0.5000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>9_555</PDBx:name>
         <PDBx:symmetry_operation>-x,-x+y,-z+1/3</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>30.6060000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="4">
         <PDBx:matrix11>0.5000000000</PDBx:matrix11>
         <PDBx:matrix12>0.8660254038</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.8660254038</PDBx:matrix21>
         <PDBx:matrix22>-0.5000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>-1.0000000000</PDBx:matrix33>
         <PDBx:name>12_555</PDBx:name>
         <PDBx:symmetry_operation>x,x-y,-z+1/3</PDBx:symmetry_operation>
         <PDBx:type>crystal symmetry operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>30.6060000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_special_symmetryCategory>
      <PDBx:pdbx_struct_special_symmetry id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>X</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>102</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
      </PDBx:pdbx_struct_special_symmetry>
   </PDBx:pdbx_struct_special_symmetryCategory>
   <PDBx:pdbx_validate_rmsd_angleCategory>
      <PDBx:pdbx_validate_rmsd_angle id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-4.81</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>130.40</PDBx:angle_target_value>
         <PDBx:angle_value>125.59</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>C6</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C5</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>N7</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>1</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>3.72</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>119.90</PDBx:angle_target_value>
         <PDBx:angle_value>123.62</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C6</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>O6</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>1</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-4.19</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>128.60</PDBx:angle_target_value>
         <PDBx:angle_value>124.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>C5</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C6</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>O6</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>1</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.73</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>119.70</PDBx:angle_target_value>
         <PDBx:angle_value>128.43</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>C3&apos;</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O3&apos;</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>P</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DC</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>2</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>Y</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>4.30</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>106.80</PDBx:angle_target_value>
         <PDBx:angle_value>111.10</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>O4&apos;</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C1&apos;</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C2&apos;</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>5</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>4.18</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>119.90</PDBx:angle_target_value>
         <PDBx:angle_value>124.08</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C6</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>O6</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>5</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-4.03</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>128.60</PDBx:angle_target_value>
         <PDBx:angle_value>124.57</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>C5</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C6</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>O6</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>5</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-7.30</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>105.70</PDBx:angle_target_value>
         <PDBx:angle_value>98.40</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>O5&apos;</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>P</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OP1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DC</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DC</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DC</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>6</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>6</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>3.66</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>106.00</PDBx:angle_target_value>
         <PDBx:angle_value>109.66</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>O4&apos;</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C4&apos;</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C3&apos;</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DC</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DC</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DC</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>6</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>6</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>4.44</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.30</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>108.30</PDBx:angle_target_value>
         <PDBx:angle_value>112.74</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>O4&apos;</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C1&apos;</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>N1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DC</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DC</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DC</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>6</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>6</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-3.77</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.60</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.90</PDBx:angle_target_value>
         <PDBx:angle_value>115.13</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C2</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>O2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DC</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DC</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DC</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>6</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>6</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.04</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>119.70</PDBx:angle_target_value>
         <PDBx:angle_value>132.74</PDBx:angle_value>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>X</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>C3&apos;</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O3&apos;</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>P</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>DC</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DC</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>DT</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>6</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>7</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>Y</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
   </PDBx:pdbx_validate_rmsd_angleCategory>
   <PDBx:pdbx_validate_rmsd_bondCategory>
      <PDBx:pdbx_validate_rmsd_bond id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O3&apos;</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C3&apos;</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>-0.039</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.006</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.419</PDBx:bond_target_value>
         <PDBx:bond_value>1.380</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
      <PDBx:pdbx_validate_rmsd_bond id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C5</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N7</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>DG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>-0.060</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.006</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.388</PDBx:bond_target_value>
         <PDBx:bond_value>1.328</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
      <PDBx:pdbx_validate_rmsd_bond id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C6</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>DC</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DC</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>2</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>0.040</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.006</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.367</PDBx:bond_target_value>
         <PDBx:bond_value>1.407</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
      <PDBx:pdbx_validate_rmsd_bond id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>X</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>X</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O3&apos;</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C3&apos;</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>DT</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>DT</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>4</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>-0.046</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.006</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.419</PDBx:bond_target_value>
         <PDBx:bond_value>1.373</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
   </PDBx:pdbx_validate_rmsd_bondCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="1QZL" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_mean>37.898</PDBx:B_iso_mean>
         <PDBx:aniso_B11>1.08</PDBx:aniso_B11>
         <PDBx:aniso_B12>0.54</PDBx:aniso_B12>
         <PDBx:aniso_B13>0.00</PDBx:aniso_B13>
         <PDBx:aniso_B22>1.08</PDBx:aniso_B22>
         <PDBx:aniso_B23>0.00</PDBx:aniso_B23>
         <PDBx:aniso_B33>-1.62</PDBx:aniso_B33>
         <PDBx:correlation_coeff_Fo_to_Fc>0.886</PDBx:correlation_coeff_Fo_to_Fc>
         <PDBx:correlation_coeff_Fo_to_Fc_free>0.819</PDBx:correlation_coeff_Fo_to_Fc_free>
         <PDBx:details>HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS</PDBx:details>
         <PDBx:ls_R_factor_R_free>0.33473</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.23978</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_all>0.24375</PDBx:ls_R_factor_all>
         <PDBx:ls_R_factor_obs>0.24375</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>2.85</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>30.57</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>23</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_all>522</PDBx:ls_number_reflns_all>
         <PDBx:ls_number_reflns_obs>489</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>4.5</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>98.46</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_B>7.852</PDBx:overall_SU_B>
         <PDBx:overall_SU_ML>0.165</PDBx:overall_SU_ML>
         <PDBx:pdbx_R_Free_selection_details>RANDOM</PDBx:pdbx_R_Free_selection_details>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>THROUGHOUT</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>0</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>MOLECULAR REPLACEMENT</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_ESU_R>1.047</PDBx:pdbx_overall_ESU_R>
         <PDBx:pdbx_overall_ESU_R_Free>0.525</PDBx:pdbx_overall_ESU_R_Free>
         <PDBx:pdbx_solvent_ion_probe_radii>0.80</PDBx:pdbx_solvent_ion_probe_radii>
         <PDBx:pdbx_solvent_shrinkage_radii>0.80</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.40</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_stereochemistry_target_values>MAXIMUM LIKELIHOOD</PDBx:pdbx_stereochemistry_target_values>
         <PDBx:solvent_model_details>BABINET MODEL WITH MASK</PDBx:solvent_model_details>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="LAST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>2.85</PDBx:d_res_high>
         <PDBx:d_res_low>30.57</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>1</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>142</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>1</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>140</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>0</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_refined_d">
         <PDBx:dev_ideal>0.021</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.021</PDBx:dev_ideal_target>
         <PDBx:number>156</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_other_d">
         <PDBx:dev_ideal>0.002</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>69</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_refined_deg">
         <PDBx:dev_ideal>2.909</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>3.000</PDBx:dev_ideal_target>
         <PDBx:number>239</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_other_deg">
         <PDBx:dev_ideal>1.421</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>3.000</PDBx:dev_ideal_target>
         <PDBx:number>173</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_chiral_restr">
         <PDBx:dev_ideal>0.141</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>21</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_refined">
         <PDBx:dev_ideal>0.010</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>73</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_other">
         <PDBx:dev_ideal>0.001</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.020</PDBx:dev_ideal_target>
         <PDBx:number>2</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbd_refined">
         <PDBx:dev_ideal>0.124</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>11</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbd_other">
         <PDBx:dev_ideal>0.227</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>59</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbtor_other">
         <PDBx:dev_ideal>0.115</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>33</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_xyhbond_nbd_refined">
         <PDBx:dev_ideal>0.210</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>2</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_vdw_refined">
         <PDBx:dev_ideal>0.112</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>7</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_vdw_other">
         <PDBx:dev_ideal>0.298</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>14</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_hbond_refined">
         <PDBx:dev_ideal>0.125</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>7</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="2.85" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.239</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_work>0.202</PDBx:R_factor_R_work>
         <PDBx:d_res_low>2.924</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>2</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>27</PDBx:number_reflns_R_work>
         <PDBx:pdbx_total_number_of_bins_used>20</PDBx:pdbx_total_number_of_bins_used>
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:B_iso_Wilson_estimate>41.857</PDBx:B_iso_Wilson_estimate>
         <PDBx:d_resolution_high>2.85</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>30.606</PDBx:d_resolution_low>
         <PDBx:entry_id>1QZL</PDBx:entry_id>
         <PDBx:number_obs>522</PDBx:number_obs>
         <PDBx:observed_criterion_sigma_F>0</PDBx:observed_criterion_sigma_F>
         <PDBx:observed_criterion_sigma_I>0</PDBx:observed_criterion_sigma_I>
         <PDBx:pdbx_Rmerge_I_obs>0.1573</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_Rsym_value>0.1507</PDBx:pdbx_Rsym_value>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_sigmaI>4.1</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_redundancy>6.6</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>96.7</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.288</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.85</PDBx:d_res_high>
         <PDBx:d_res_low>3.00</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>2.1</PDBx:meanI_over_sigI_obs>
         <PDBx:number_unique_all>69</PDBx:number_unique_all>
         <PDBx:pdbx_Rsym_value>0.288</PDBx:pdbx_Rsym_value>
         <PDBx:pdbx_redundancy>6.8</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>99.5</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>REFMAC</PDBx:name>
         <PDBx:version>5.1.24</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>data reduction</PDBx:classification>
         <PDBx:name>MOSFLM</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:name>CCP4</PDBx:name>
         <PDBx:version>(SCALA)</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>XTALVIEW</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="1QZL">
         <PDBx:pdbx_descriptor>5&apos;-D(*GP*CP*AP*TP*GP*CP*T)-3&apos;</PDBx:pdbx_descriptor>
         <PDBx:title>GCATGCT + Cobalt</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1">
      </PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_connCategory>
      <PDBx:struct_conn id="metalc1">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.512</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>X</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>101</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>B</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>X</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>DG</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>1</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>N7</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>DG</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>1</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>1_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
      <PDBx:struct_conn id="metalc2">
         <PDBx:conn_type_id>metalc</PDBx:conn_type_id>
         <PDBx:pdbx_dist_value>2.327</PDBx:pdbx_dist_value>
         <PDBx:ptnr1_auth_asym_id>X</PDBx:ptnr1_auth_asym_id>
         <PDBx:ptnr1_auth_comp_id>CO</PDBx:ptnr1_auth_comp_id>
         <PDBx:ptnr1_auth_seq_id>101</PDBx:ptnr1_auth_seq_id>
         <PDBx:ptnr1_label_asym_id>B</PDBx:ptnr1_label_asym_id>
         <PDBx:ptnr1_label_atom_id>CO</PDBx:ptnr1_label_atom_id>
         <PDBx:ptnr1_label_comp_id>CO</PDBx:ptnr1_label_comp_id>
         <PDBx:ptnr1_label_seq_id xsi:nil="true" />
         <PDBx:ptnr1_symmetry>1_555</PDBx:ptnr1_symmetry>
         <PDBx:ptnr2_auth_asym_id>X</PDBx:ptnr2_auth_asym_id>
         <PDBx:ptnr2_auth_comp_id>DG</PDBx:ptnr2_auth_comp_id>
         <PDBx:ptnr2_auth_seq_id>5</PDBx:ptnr2_auth_seq_id>
         <PDBx:ptnr2_label_asym_id>A</PDBx:ptnr2_label_asym_id>
         <PDBx:ptnr2_label_atom_id>N7</PDBx:ptnr2_label_atom_id>
         <PDBx:ptnr2_label_comp_id>DG</PDBx:ptnr2_label_comp_id>
         <PDBx:ptnr2_label_seq_id>5</PDBx:ptnr2_label_seq_id>
         <PDBx:ptnr2_symmetry>12_555</PDBx:ptnr2_symmetry>
      </PDBx:struct_conn>
   </PDBx:struct_connCategory>
   <PDBx:struct_conn_typeCategory>
      <PDBx:struct_conn_type id="metalc">
      </PDBx:struct_conn_type>
   </PDBx:struct_conn_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="1QZL">
         <PDBx:pdbx_keywords>DNA</PDBx:pdbx_keywords>
         <PDBx:text>DNA quadruplex, DNA</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>1QZL</PDBx:db_code>
         <PDBx:db_name>PDB</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_db_accession>1QZL</PDBx:pdbx_db_accession>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>1</PDBx:db_align_beg>
         <PDBx:db_align_end>7</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>1QZL</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>1</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>7</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>1QZL</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>X</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>7</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>BINDING SITE FOR RESIDUE CO X 101</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>2</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>X</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>DG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>DG</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>2</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>X</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>DG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>5</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>DG</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>2</PDBx:pdbx_num_res>
         <PDBx:symmetry>12_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="1QZL">
         <PDBx:Int_Tables_number>180</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 62 2 2</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
